PAI Gene Information


Name : HP0524
Accession : BAD13940.1
PAI name : cag PAI
PAI accession : AB120422
Strain : Helicobacter pylori 2017
Virulence or Resistance: Virulence
Product : cag pathogenicity island protein
Function : -
Note : similar to virD4, H.pylori 26695 gene HP0524:cag5, J99 gene JHP0473, NCTC11638 gene ORF10:cag-beta
Homologs in the searched genomes :   45 hits    ( 43 protein-level,   2 DNA-level )  
Publication :
    -Azuma,T., Yamakawa,A. and Yamazaki,S., "Direct Submission", Submitted (12-SEP-2003) Takeshi Azuma, University of Fukui Faculty of Medical Sciences, General Medicine Second Department of Internal Medicine; Shimoaizuki 23-3, Matsuoka-cho, Yoshida-gun, Fukui 910-1193, Japan (E-mail:azuma@fmsrsa.fukui-med.ac.jp, Tel:8.

    -Azuma,T., Yamakawa,A., Yamazaki,S., Ohtani,M., Ito,Y., Muramatsu,A., Suto,H., Yamazaki,Y., Keida,Y., Higashi,H. and Hatakeyama,M., "Distinct diversity of the cag pathogenicity island among Helicobacter pylori strains in Japan", J. Clin. Microbiol. 42 (6), 2508-2517 (2004) PUBMED 15184428.


DNA sequence :
ATGGAAGACTTGTTGTATAACACCTTATATTTCATAGAGGATTATAAGTTGGTTGTTATTTTTAGTTTCATAGGGTTAAT
AGCGTTATTTTTTCTCTACAAATTCATAAAAGCTCAAAAAAAAGCTTTTAAAGATAAAGCTAACCAACCTCAAAAGAAAA
AAAACTTTAAAGAAATCGTTATAGAGGGGCTGAAAGAAAGAGTTAAAACCTTTGGCTTTTGGTTACAAGCGACACTATTA
CTATCCTATTCTTTTATCACATCAGGGTTATTTTTCTTGATCCTATTAGGTAATTTTTATGATGATAATAAATTGCCTGA
GAGTGATGATGATCTTTTTGATATATGGATCTATGCGATACAAGATTTTCCTGCATACTATTTTAAGGCGCTTTGTTTTA
GTTCACTCAAGATTTATGGGTTCAATATATCCTTAGTCGTATATAGTTCTATTTTATGCTCTTATATATTCATTACCTTT
TTTGTGTGGTTCTTAAAATACTTAACTCGGACTAGAGACATAGGAGCGAATAAAAAAGTTGATGATCTCTTTGGTAGCGC
GAGTTGGGAGAGCGAAGAAAAAATGATCAAAGCTAAACTTATCACACCCAATAATAAAAAACGCGCCTTTGACAAACGAG
AGGTTATTGTGGGCAGGCGTGGTTTGGGGGATTTTATCGCTTATGCAGGACAGGCGTTCATTGGCTTGATTGCTCCTACC
AGAAGCGGTAAGGGGGTGGGTTTTATCATGCCTAATATGATCAATTATCCTCAAAATATCGTTGTGTTTGACCCTAAGGC
TGACACTATGGAAACTTGCGGAAAAATCAGAGAAAAACGCTTCAACCAAAAAGTGTTCATCTATGAACCTTTCTCCTTAA
AAACACACCGATTTAATCCTTTCGCTTATGTGGATTTTGGTAATGATGTGGTTTTGACTGAAGACATACTCTCTCAAATT
GACACACGCCTAAAAGGTCATGGGATGGTGGCTAGTGGGGGGGATTTTTCCACTCAAATCTTTGGATTGGCAAAGCTCGT
GTTCCCTGAAAGACCTAATGAAAAAGATCCTTTTTTTAGCAATCAAGCGCGAAATCTTTTTGTCATCAATTGCAATATTT
ATAGGGATCTCATGTGGACTAAAAAGGGGCTTGAGTTTGTCAAAAGAAAAAAAATCATCATGCCTGAAACCCCCACGATG
TTTTTCATAGGTTCTATGGCAAGCGGTATCAACTTGATTGATGAAGACACAAACATGGAAAAAGTCGTGTCTCTGATGGA
ATTTTTTGGAGGTGAAGAAGATAAGAGTGGCGATAATATAAGAGTGCTTAGTCCTGCCACTAGAAACATGTGGAATAATT
TCAAGACAATGGGCGGCGCTAAAGAAACTTACAGCTCTGTTCAAGGGGTCTATACTTCAGCGTTTGCCCCCTACAATAAC
GCCATGATCAGAAATTTCACGAGCGCTAATGATTTTGATTTCAGGCGTTTAAGGATTGATGCAGTGAGTATTGGCGTGAT
CGCTAATCCTAAAGAAAGCACTATTGTTGGGCCGATATTAGAGCTGTTTTTCAATGTGATGATTTATAGCAACCTTATTC
TGCCAATCCATGATCCACAATGCAAAAGAAGTTGTTTAATGCTCATGGACGAATTTACGCTTTGTGGCTATTTAGAGACC
TTTGTTAAAGCGGTAGGGATCATGGCAGAATACAACATGCGCCCTGCGTTTGTGTTTCAAAGTAAGGCGCAACTAGAGAA
TGACCCCCCACTTGGTTATGGTAGGAATGGCGCTAAGACTATTTTAGACAACCTTTCTTTGAATATGTATTATGGGATTA
ACAACGATAACTACTATGAACATTTTGAAAAACTTTCTAAGGTGTTAGGGAAATACACCAGGCAAGATGTGAGCCGAAGC
ATTGATGATAATACCGGTAAGACCAATACTTCTATCAGCAACAAGGAGCGCTTTTTGATGACCCCTGATGAATTGATGAC
TATGGGCGATGAGCTTATCATTCTAGAAAACACGCTCAAACCCATCAAGTGCCACAAGGCACTTTACTATGATGATCCAT
TCTTCACTGATGAGCTTATTAAGGTAAGTCCAAGCTTGAGCAAGAAATGCAAATTAGGAAAAGTGCCTAATCAAGCAACA
TTCTATGATGATTTGCAAGCCGCTAAAACTAGAGGCGAATTGAGCTATGATAAATCTTTAGTGCCTGTGGGTTCAAGCGA
ACTGTGA

Protein sequence :
MEDLLYNTLYFIEDYKLVVIFSFIGLIALFFLYKFIKAQKKAFKDKANQPQKKKNFKEIVIEGLKERVKTFGFWLQATLL
LSYSFITSGLFFLILLGNFYDDNKLPESDDDLFDIWIYAIQDFPAYYFKALCFSSLKIYGFNISLVVYSSILCSYIFITF
FVWFLKYLTRTRDIGANKKVDDLFGSASWESEEKMIKAKLITPNNKKRAFDKREVIVGRRGLGDFIAYAGQAFIGLIAPT
RSGKGVGFIMPNMINYPQNIVVFDPKADTMETCGKIREKRFNQKVFIYEPFSLKTHRFNPFAYVDFGNDVVLTEDILSQI
DTRLKGHGMVASGGDFSTQIFGLAKLVFPERPNEKDPFFSNQARNLFVINCNIYRDLMWTKKGLEFVKRKKIIMPETPTM
FFIGSMASGINLIDEDTNMEKVVSLMEFFGGEEDKSGDNIRVLSPATRNMWNNFKTMGGAKETYSSVQGVYTSAFAPYNN
AMIRNFTSANDFDFRRLRIDAVSIGVIANPKESTIVGPILELFFNVMIYSNLILPIHDPQCKRSCLMLMDEFTLCGYLET
FVKAVGIMAEYNMRPAFVFQSKAQLENDPPLGYGRNGAKTILDNLSLNMYYGINNDNYYEHFEKLSKVLGKYTRQDVSRS
IDDNTGKTNTSISNKERFLMTPDELMTMGDELIILENTLKPIKCHKALYYDDPFFTDELIKVSPSLSKKCKLGKVPNQAT
FYDDLQAAKTRGELSYDKSLVPVGSSEL