PAI Gene Information


Name : prfA
Accession : CAA05714.1
PAI name : LIPI-1
PAI accession : AJ002742
Strain : Listeria monocytogenes 07PF0776
Virulence or Resistance: Virulence
Product : PrfA
Function : -
Note : -
Homologs in the searched genomes :   39 hits    ( 39 protein-level )  
Publication :
    -Ripio,M.T., Dominguez-Bernal,G., Lara,M., Suarez,M. and Vazquez-Boland,J.A., "A Gly145Ser substitution in the transcriptional activator PrfA causes constitutive overexpression of virulence factors in Listeria monocytogenes", J. Bacteriol. 179 (5), 1533-1540 (1997) PUBMED 9045810.

    -Vazquez-Boland,J.A., "Direct Submission", Submitted (10-NOV-1997) Vazquez-Boland J.A., Microbiology and Immunology, Complutense University, Veterinary Faculty, Complutense University, 28040 Madrid, SPAIN.


DNA sequence :
ATGAACGCTCAAGCAGAAGAATTCAAAAAATATTTAGAAACTAACGGGATAAAACCAAAACAATTTCATAAAAAAGAACT
TATTTTTAACCAATGGGATCCACAAGAATATTGTATTTTCCTATATGATGGTATTACAAAGCTTACAAGTATTAGCGAGA
ACGGGACCATCATGAATTTACAATACTATAAAGGTGCTTTCGTTATAATGTCTGGCTTTATCGATACAGAAACATCGGTT
GGCTATTATAATTTAGAAGTCATTAGCGAACAGGCTACCGCATACGTTATCAAAATAAACGAACTAAAAGAACTACTGAG
CAAGAATCTTACGCACTTTTTCTATGTTTTCCAAACCCTACAAAAACAAGTTTCATACAGCCTAGCCAAATTTAATGATT
TTTCGATTAACGGGAAGCTCGGCTCTATTTGCGGTCAACTTTTAATCCTGACCTATGTGTATGGTAAAGAAACTCCTGAT
GGCATCAAGATTACACTGGATAATTTAACAATGCAGGAGTTAGGCTATTCAAGCGGTATCGCACATAGCTCAGCTGTTAG
CAGAATTATTTCTAAATTAAAGCAAGAGAAAGTTATCGTGTATAAAAATTCATGCTTTTATGTACAAAATCTTGATTATC
TCAAAAGATATGCTCCTAAATTAGATGAATGGTTTTATTTAGCATGTCCTGCTACTTGGGGAAAATTAAATTAA

Protein sequence :
MNAQAEEFKKYLETNGIKPKQFHKKELIFNQWDPQEYCIFLYDGITKLTSISENGTIMNLQYYKGAFVIMSGFIDTETSV
GYYNLEVISEQATAYVIKINELKELLSKNLTHFFYVFQTLQKQVSYSLAKFNDFSINGKLGSICGQLLILTYVYGKETPD
GIKITLDNLTMQELGYSSGIAHSSAVSRIISKLKQEKVIVYKNSCFYVQNLDYLKRYAPKLDEWFYLACPATWGKLN