PAI Gene Information


Name : escR
Accession : CAI43889.1
PAI name : LEE
PAI accession : AJ303141
Strain : Escherichia coli 042
Virulence or Resistance: Virulence
Product : EscR protein
Function : -
Note : -
Homologs in the searched genomes :   662 hits    ( 662 protein-level )  
Publication :
    -Jores,J., "Direct Submission", Submitted (02-JAN-2001) Jores J., Institut fuer Mikrobiologie und Tierseuchen, Freie Universitaet Berlin, Philippstrasse 13, 10115 Berlin, Berlin, 10115, GERMANY REMARK revised by [3].

    -Jores,J., "Direct Submission", Submitted (09-SEP-2004) Jores J., Institut fuer Mikrobiologie und Tierseuchen, Freie Universitaet Berlin, Philippstrasse 13, 10115 Berlin, Berlin, 10115, GERMANY.

    -Jores,J., Rumer,L., Kiessling,S., Kaper,J.B. and Wieler,L.H., "A novel locus of enterocyte effacement (LEE) pathogenicity island inserted at pheV in bovine Shiga toxin-producing Escherichia coli strain O103:H2", FEMS Microbiol. Lett. 204 (1), 75-79 (2001) PUBMED 11682182.

    -Jores,J., Wagner,S., Rumer,L., Eichberg,J., Laturnus,C., Kirsch,P., Schierack,P., Tschape,H. and Wieler,L.H., "Description of a 111-kb pathogenicity island (PAI) encoding various virulence features in the enterohemorrhagic E. coli (EHEC) strain RW1374 (O103:H2) and detection of a similar PAI in other EHEC strains of serotype 0103:H2", Int. J. Med. Microbiol. 294 (7), 417-425 (2005) PUBMED 15715170.

    -Rumer,L., Jores,J., Kirsch,P., Cavignac,Y., Zehmke,K. and Wieler,L.H., "Dissemination of pheU- and pheV-located genomic islands among enteropathogenic (EPEC) and enterohemorrhagic (EHEC) E. coli and their possible role in the horizontal transfer of the locus of enterocyte effacement (LEE)", Int. J. Med. Microbiol. 292 (7-8), 463-475 (2003) PUBMED 12635929.


DNA sequence :
ATGTCTCAATTAATGACCATTGGCTCACAGCCAATATTTTTAATTATTGTATTTTTTCTTTTATCATTACTGCCTATATT
TGTTGTTATTGGTACTTCATTCCTGAAAATTTCGATTGTATTGGGGATTCTGAAGAACGCATTAGGTATTCAACAGGTAC
CACCAAATATGGCGCTAACATCAGTATCTTTGATACTGACAATGTTTATTATGTCTCCGATAATATTACAGATAAATGAT
AATATTTCTCAGGAACCAATCAATTACACCGACTCTGATTTTTTTCAAAAAGTTGATGAAAAAATATTATCACCATACCG
CGGTTTTTTAGAAAAAAATACAGAGAAAGAAAATGTTGAGTTTTTTGAACGTGCAGCTCAAAAAAAATTGGGTAATGAAA
CTATCTTAAAAAAAGACTCTCTATTTATACTGTTACCAGCTTTCACGATGGGGCAGCTTGAAGCTGCATTCAAGATAGGT
TTTTTGCTCTATTTACCTTTTATTGCGATAGATTTGATCATTTCCAATATCTTATTGGCCTTGGGTATGATGATGGTATC
GCCAGTAACAATTTCGATTCCTTTTAAGATCTTGTTATTCATTCTTGTTGGAGGCTGGCAAAAATTATTCGAATTTCTGT
TGGTGGTGAATTGA

Protein sequence :
MSQLMTIGSQPIFLIIVFFLLSLLPIFVVIGTSFLKISIVLGILKNALGIQQVPPNMALTSVSLILTMFIMSPIILQIND
NISQEPINYTDSDFFQKVDEKILSPYRGFLEKNTEKENVEFFERAAQKKLGNETILKKDSLFILLPAFTMGQLEAAFKIG
FLLYLPFIAIDLIISNILLALGMMMVSPVTISIPFKILLFILVGGWQKLFEFLLVVN