PAI Gene Information


Name : siaC (NMB0068)
Accession : NP_273132.1
PAI name : IHT-A
PAI accession : NC_003112_P1
Strain : Neisseria meningitidis 053442
Virulence or Resistance: Not determined
Product : polysialic acid capsule biosynthesis protein SiaC
Function : -
Note : identified by similarity to EGAD:19609; match to protein family HMM PF01354; match to protein family HMM PF03102
Homologs in the searched genomes :   54 hits    ( 54 protein-level )  
Publication :
    -Tettelin,H., Saunders,N.J., Heidelberg,J., Jeffries,A.C., Nelson,K.E., Eisen,J.A., Ketchum,K.A., Hood,D.W., Ciecko,A., Peden,J.F., Dodson,R.J., Nelson,W.C., Gwinn,M.L., Peterson,J.D., Hickey,E.K., Haft,D.H., Salzberg,S.L., White,O., Fleischmann,R.D., Doug, "Direct Submission", Submitted (18-MAY-2005) The Institute for Genomic Research, 9712 Medical Center Dr, Rockville, MD 20850, USA REMARK Sequence update by submitter.

    -Tettelin,H., Saunders,N.J., Heidelberg,J., Jeffries,A.C., Nelson,K.E., Eisen,J.A., Ketchum,K.A., Hood,D.W., Ciecko,A., Peden,J.F., Dodson,R.J., Nelson,W.C., Gwinn,M.L., Peterson,J.D., Hickey,E.K., Haft,D.H., Salzberg,S.L., White,O., Fleischmann,R.D., Doug, "Direct Submission", Submitted (19-SEP-2001) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA.

    -Tettelin,H., Saunders,N.J., Heidelberg,J., Jeffries,A.C., Nelson,K.E., Eisen,J.A., Ketchum,K.A., Hood,D.W., Ciecko,A., Peden,J.F., Dodson,R.J., Nelson,W.C., Gwinn,M.L., Peterson,J.D., Hickey,E.K., Haft,D.H., Salzberg,S.L., White,O., Fleischmann,R.D., Doug, "Direct Submission", Submitted (17-MAR-2000) The Institute for Genomic Research, 9712 Medical Center Dr, Rockville, MD 20850, USA.

    -Tettelin,H., Saunders,N.J., Heidelberg,J., Jeffries,A.C., Nelson,K.E., Eisen,J.A., Ketchum,K.A., Hood,D.W., Peden,J.F., Dodson,R.J., Nelson,W.C., Gwinn,M.L., DeBoy,R., Peterson,J.D., Hickey,E.K., Haft,D.H., Salzberg,S.L., White,O., Fleischmann,R.D., Dough, "Complete genome sequence of Neisseria meningitidis serogroup B strain MC58", Science 287 (5459), 1809-1815 (2000) PUBMED 10710307.


DNA sequence : 
ATGCAAAACAACAACGAATTTAAAATTGGTAATCGTTCAGTAGGTTACAACCACGAACCATTGATTATCTGTGAAATCGG
CATCAATCATGAAGGCTCTTTAAAAACAGCTTTTGAAATGGTTGATGCTGCCTATAATGCAGGCGCTGAAGTTGTTAAAC
ATCAAACACACATCGTTGAAGACGAAATGTCTGATGAGGCCAAACAAGTCATTCCAGGCAATGCAGATGTCTCTATTTAT
GAAATTATGGAACGTTGCGCCCTGAATGAAGAAGATGAGATTAAATTAAAAGAATACGTAGAGAGTAAGGGTATGATTTT
TATCAGTACTCCTTTCTCTCGTGCAGCTGCTTTACGATTACAACGTATGGATATTCCAGCATATAAAATCGGCTCTGGCG
AATGTAATAACTACCCATTAATTAAACTGGTGGCCTCTTTTGGTAAGCCTATTATTCTCTCTACCGGCATGAATTCTATT
GAAAGCATCAAAAAGTCGGTAGAAATTATTCGAGAAGCAGGGGTACCTTATGCTTTGCTTCACTGTACCAACATCTACCC
AACCCCTTACGAAGATGTTCGATTGGGTGGTATGAACGATTTATCTGAAGCCTTTCCAGACGCAATCATTGGCCTGTCTG
ACCATACCTTAGATAACTATGCTTGCTTAGGAGCAGTAGCTTTAGGCGGTTCGATTTTAGAGCGTCACTTTACTGACCGC
ATGGATCGCCCAGGTCCGGATATTGTATGCTCTATGAATCCGGATACTTTTAAAGAGCTCAAGCAAGGCGCTCATGCTTT
AAAATTGGCACGCGGCGGCAAAAAAGACACGATTATCGCGGGAGAAAAGCCAACTAAAGATTTCGCCTTTGCATCTGTCG
TAGCAGATAAAGACATTAAAAAAGGAGAACTGTTGTCCGGAGATAACCTATGGGTTAAACGCCCAGGCAATGGAGACTTC
AGCGTCAACGAATATGAAACATTATTTGGTAAGGTCGCTGCTTGCAATATTCGCAAAGGTGCTCAAATCAAAAAAACTGA
TATTGAATAA

Protein sequence : 
MQNNNEFKIGNRSVGYNHEPLIICEIGINHEGSLKTAFEMVDAAYNAGAEVVKHQTHIVEDEMSDEAKQVIPGNADVSIY
EIMERCALNEEDEIKLKEYVESKGMIFISTPFSRAAALRLQRMDIPAYKIGSGECNNYPLIKLVASFGKPIILSTGMNSI
ESIKKSVEIIREAGVPYALLHCTNIYPTPYEDVRLGGMNDLSEAFPDAIIGLSDHTLDNYACLGAVALGGSILERHFTDR
MDRPGPDIVCSMNPDTFKELKQGAHALKLARGGKKDTIIAGEKPTKDFAFASVVADKDIKKGELLSGDNLWVKRPGNGDF
SVNEYETLFGKVAACNIRKGAQIKKTDIE