Name : stpA
Accession : NP_457272.1
PAI name : SPI-1
PAI accession : NC_003198_P5
Strain : Salmonella enterica RSK2980
Virulence or Resistance: Virulence
Product : tyrosine phosphatase (associated with virulence)
Function : -
Note : Previously characterised Salmonella typhi StpA a protein related to both Yersinia YopE cytotoxin and YopH tyrosine phosphatase TR:P74851 (EMBL:X92546) (543 aa) fasta scores: E(): 0, 100.0% id in 543 aa. Also higly similar to Salmonella typhimurium protein
Homologs in the searched genomes : 37 hits ( 33 protein-level, 4 DNA-level )
Publication :
-Parkhill,J., "Direct Submission", Submitted (25-OCT-2001) Submitted on behalf of the Salmonalla sequencing team, Sanger Centre, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, UK.
-Parkhill,J., Dougan,G., James,K.D., Thomson,N.R., Pickard,D., Wain,J., Churcher,C., Mungall,K.L., Bentley,S.D., Holden,M.T., Sebaihia,M., Baker,S., Basham,D., Brooks,K., Chillingworth,T., Connerton,P., Cronin,A., Davis,P., Davies,R.M., Dowd,L., White,N., , "Complete genome sequence of a multiple drug resistant Salmonella enterica serovar Typhi CT18", Nature 413 (6858), 848-852 (2001) PUBMED 11677608.
-Parkhill,J., Dougan,G., James,K.D., Thomson,N.R., Pickard,D., Wain,J., Churcher,C., Mungall,K.L., Bentley,S.D., Holden,M.T., Sebaihia,M., Baker,S., Basham,D., Brooks,K., Chillingworth,T., Connerton,P., Cronin,A., Davis,P., Davies,R.M., Dowd,L., White,N., , "Direct Submission", Submitted (10-SEP-2013) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA.
| DNA sequence : |  |
ATGCTAAGGTATGATGAGAGGAAGTTGAATAATTTAACATTGTCTTCATTTTCAAAATCTGGCGTGTCGAGTGATACCCG
GCTATATATTGCTAAGGAAAATACTGATAAGGCATATGTTGCGCCTGAAAAATTTTCGTCAAAAGTATTAACCTGGCTTG
GAAAAATGCCCTTATTTAAAAACACTGAAGTGGTGCAAAAACACACGGAAAATATCAGAGTACAGAACCAAAAGATTTTA
CAGACATTTCTCCAGGCATTAACGGAAAAATATGGGGAAAAAGCGGTCAATAATGCTTTGTACATGTCCAGTATAAATAT
GAACAAACCCCTTACCCAACGTTTAGTAGTGCAGATCACGGAGTGTGTAAAAGGTGCTGACGGAGGGTTTATAAATCTTA
TTAAGAACAAGGATAATGTTGGTGTCATGAATGCCGCTTTAGTCATAAAAGGCGGCGATACAAAAGTGACAGAACAAAAT
AACGATGTTGGTGCAGAAAGTAAGCAACCTTTACTCGATATCGCGCTAAAGGGACTTAAGAGAACAATACCGCAACTGGA
ACAAATGGATGGAAATAGCCTGCGAGAAAACTTCCAGGAGATGGCTTCAGGTAACGGCCCGCTGCGTTCATTAATGACGA
ATTTACAGAGTTTAAATAAAATTCCAGAGGCTAAACAACTTAATGATTATGTTACAACGTTAAAAAATATTCAGATAGGA
GCAGACAGGTTCTCACAATGGGGAACCTGTGGGGGAGAGGTTGAGAGGTGGATTGATAAAGCCTCTACTCATGAATTAAC
CCAAGCGGTAAAAAAAATTCACGTTATTGCTAAAGAACTGAAAAACGTTACAGCTGAACTTGAGAAAATAAAAGCCGGTG
CGTCAATGCCACAGACGATGAGCGGACCGACACTGGGCCTGGCACGGTTTGCGGTCAGCAGCATTCCCATTAATCAGCAA
ACCCAGGTGAAACTGAGCGATGGAATGCCTGTGCCAGTGAATACGTTAACTTTTGACGGTAAGCCTGTGGCATTAGCCGG
TTCGTGCCCAAAAAATACGCCGGATGCGCTGGAAGCGCATATGAAAATGCTTCTTGAAAAAGAATGTTCGTGCCTGGTGG
TGTTAACGTCGGAAGATCAGATGCAGGCAAAACAATTACCAGCCTATTTCAGAGGGAGCTACACCTTTGGCGAGGTGCAT
ACCAACAGCCAAAAAGTGAGCTCAGCCAGTCAGGGAGGAGCGATAGACCAATACAATATGCAACTGTCCTGCGGGGAAAA
GCGGTATACAATCCCGGTATTGCATGTGAAAAATTGGCCAGATCACCAGCCGTTACCGTCTACTGATCAGTTAGAATACC
TGGCGGATAGGGTGAAAAATAGTAACCAAAATGGCGCGCCGGGGCGTAGTTCATCAGATAAGCATTTACCGATGATTCAT
TGTCTGGGCGGAGTGGGAAGAACCGGAACGATGGCGGCGGCTCTTGTACTTAAGGATAATCCTCATAGTAATCTGGAGCA
GGTACGTGCAGATTTCCGGAATTCACGGAACAATAGAATGCTGGAAGACGCCTCACAGTTTGTACAACTAAAAGCAATGC
AAGCCCAGTTGCTTATGACGACGGCAAGCTGA
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| Protein sequence : | |
MLRYDERKLNNLTLSSFSKSGVSSDTRLYIAKENTDKAYVAPEKFSSKVLTWLGKMPLFKNTEVVQKHTENIRVQNQKIL
QTFLQALTEKYGEKAVNNALYMSSINMNKPLTQRLVVQITECVKGADGGFINLIKNKDNVGVMNAALVIKGGDTKVTEQN
NDVGAESKQPLLDIALKGLKRTIPQLEQMDGNSLRENFQEMASGNGPLRSLMTNLQSLNKIPEAKQLNDYVTTLKNIQIG
ADRFSQWGTCGGEVERWIDKASTHELTQAVKKIHVIAKELKNVTAELEKIKAGASMPQTMSGPTLGLARFAVSSIPINQQ
TQVKLSDGMPVPVNTLTFDGKPVALAGSCPKNTPDALEAHMKMLLEKECSCLVVLTSEDQMQAKQLPAYFRGSYTFGEVH
TNSQKVSSASQGGAIDQYNMQLSCGEKRYTIPVLHVKNWPDHQPLPSTDQLEYLADRVKNSNQNGAPGRSSSDKHLPMIH
CLGGVGRTGTMAAALVLKDNPHSNLEQVRADFRNSRNNRMLEDASQFVQLKAMQAQLLMTTAS
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