PAI Gene Information


Name : S3169 (S3169)
Accession : NP_838460.1
PAI name : SHI-1
PAI accession : NC_004741_P1
Strain : Shigella flexneri 2002017
Virulence or Resistance: Not determined
Product : superfamily I DNA helicase
Function : -
Note : residues 1 to 1171 of 1171 are 92.99 pct identical to residues 1 to 1171 of 1171 from GenPept : >gb|AAL23307.1| (AE008910) superfamily I DNA helicases [Salmonella typhimurium LT2]
Homologs in the searched genomes :   42 hits    ( 41 protein-level,   1 DNA-level )  
Publication :
    -Wei,J., Goldberg,M.B., Burland,V., Venkatesan,M.M., Deng,W., Fournier,G., Mayhew,G.F., Plunkett,G. III, Rose,D.J., Darling,A., Mau,B., Perna,N.T., Payne,S.M., Runyen-Janecky,L.J., Zhou,S., Schwartz,D.C. and Blattner,F.R., "Complete genome sequence and comparative genomics of Shigella flexneri serotype 2a strain 2457T", Infect. Immun. 71 (5), 2775-2786 (2003) PUBMED 12704152 REMARK Erratum:[Infect Immun. 2003 Jul;71(7):4223].

    -Wei,J., Goldberg,M.B., Burland,V., Venkatesan,M.M., Deng,W., Fournier,G., Mayhew,G.F., Plunkett,G. III, Rose,D.J., Darling,A., Mau,B., Perna,N.T., Payne,S.M., Runyen-Janecky,L.J., Zhou,S., Schwartz,D.C. and Blattner,F.R., "Direct Submission", Submitted (23-APR-2003) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA.

    -Wei,J., Goldberg,M.B., Burland,V., Venkatesan,M.M., Deng,W., Fournier,G., Mayhew,G.F., Plunkett,G. III, Rose,D.J., Darling,A., Mau,B., Perna,N.T., Payne,S.M., Runyen-Janecky,L.J., Zhou,S., Schwartz,D.C. and Blattner,F.R., "Direct Submission", Submitted (13-JUN-2002) Genetics Laboratory, University of Wisconsin - Madison, 445 Henry Mall, Madison, WI 53706, USA.


DNA sequence :
ATGGATGAAAATGCTTTAGGGTTTGCCTCATACTGGCGCAACTCGCTTGCGGATGCTGAGTCAGGAAAGGGCAGTTTTAA
ACGGAAAGACGCCCAAAATTTCACTCACTGGCATGGGATAGCGGCGGGACGTCTTGACGAAGCGATTGTCAGTAAATTTT
TTGAGGGAGAAAAAGACGATGTCGAAACGGTCGATGTCATCTTGCGCCCAAAAGTTTATTTCCGGTTACTGCAGCATGGT
AAGGACCGTTCCGCAGGCGCGCCTGATATTGTTACCCCGATAGTGACGCCAGCCTTGCTAAGCCGTGAGGGTTTTTTATA
TCCGACGCCAGCGACCTCCATTCCCAGAGACCTGCTTGAACCTTTGCCAAAAGGAGCATTTTCGATTGGTGAGATTGGGC
AGTATGACAAATACAAGACGACCCATACCACGTTCTCTATCAACTTTGATGACAGCGTTGATAAGACTGCCGAAACGGAT
GAAGAACGGGAAGCACGATATGCCGCCTTGCAGCAGGAGTGGCGTCAATATCTGTATGACTCAGAGAGGCTACTGAAGAG
CGTTGCCGGCGACTGGATTGAAAAACCTGAGCAATATGAACTCGCTGAGCACGGTTATATTGTTAAAACGGCTCAATCTG
GCGGTGCCAGTTCCCATATCCTTTCTCTTTATGATCACCTGCTTGTTTGCAATAAGGATGTGCCGCTCTTCAATCGCTTC
GCCTCGCGAGAGGTTCATGCTGCAGAGTCTTTGCTGGCCCCAGGAGCAAAATTCAGCGACAGGCTTGGACACTCCGGAGA
TAAGTTTCCGCTGGCAAAGGCTCAGCGCGATGCCTTAAGCCATTTTCTGGATGCAAGACATGGCGATATCCTTGCTGTTA
ATGGCCCTCCGGGAACCGGAAAAACCACGCTGGTGCTTTCTATCATCGCCACGCAGTGGGCCAGAGCGGCTCTCGAAAAA
TCTGAGCCTCCGGTTATTATCGCGACTTCAACGAATAACCAGGCTGTAACGAACATTATTGAGGCATTCGGGAAAGACTT
TTCGCAAGGTTCAGGTGCGATGGCCGGGCGATGGTTGCCAGAGCTGAAAAGCTTCGGTGCTTATTTTCCCTCAAGCAGTC
GTAAAGCTGAGGCAGCCAAAAAATATCAAACTGAAGATTTCTTCAACCAGGTTGAGTCAAAAGAGTATGTAGAGGATGCA
CTGCTGTTTTATCTGGAAAAGGCTAAGGCAGCCTTTCCTGGAAAAGAGTGTTCATCCCCTGAAAAGGTCATTGAACTCTT
GCATGGTCAGTTGGCAGCAAAATCTGAGCAACTGATAAGACTGAACGCAACATGGCAAACGTTAAGCCAGATTCGGGCTG
CGCGTGAGCTTATTGCTAATGATATTGAGCAATATCTCGATAATTTAAATAAATTACTTTCCGGACAAGAACAAAAAGTC
ACTCTACTGAAGAGTGCTAAAACGGAATGGAAAAAATATCGCGCCGGTGAATCACTGATCTATTCATTATTTTCCTGGCT
CCCGGCGGTTCGCAATAAGCGACAGTACCAAATACAGCTGTTTCTCGAAGATAAATTAGGCGCGCTGATTGCAGGAAATC
AGTGGTCTGATCCTGAAACTATCGAACGTAATATTGATGGGCTGCTCAATTCCGCTGAGCGCGAGCAAACAACATACCGG
CAGCAGATTGACTCCGCCCATGAAATCGTTCTTAAAGAACAGCAGGCGGTTCAGGAGTGGCAGAGGCTGGCATTTGATTT
AGGGTATGAGGGCGACGAGGAACTGAGCTTCTCACAGGCCGATGAACTGGCTGATACGCAGATTCGCTTCCCTGCATTTT
TACTGACGACTCACTACTGGGAAGGTCGTTGGCTGATGGATATGGCCAGCATTGATGATCTGCAGGACGAGAAGAAGAAA
AAAGGTGCTAAAGGGGTAACCGCCCGTTGGCAACGTCGAATGAAACTCACGCCATGTGTGGTGATGACATGCTATATGCT
GCCCGGTAATATGCAGATAAGTGAGCACAAAGGACAACGTAAATTCGAGAAAAGTTATTTGTATGATTTTGCCGATTTAC
TCATTGTCGATGAAGCCGGGCAGGTGCTTCCTGAAGTGGCTGCTGCCTCGTTTGCATTAGCTAAGAAGGCATTAGTGATT
GGCGATACGGAGCAGATCCCGCCAATATGGAGTATTGCTCCTGCGATTGATGTCGGTAACATGCTGGCGGAAAAAATTCT
GTCTGGCAGTACGCAAGAAGAGATTACCGAGAAATATACGGCAATCGCAGACCTTGGTAAAAGTGCCGCATCTGGCAGCG
TTATGAAAATAGCGCAGTTTGCTTCGCGCTATCAATATGATCCCGAACTGGCTCGTGGTATGTACCTATATGAACACCGC
CGGTGCTACGACAATATTATTGGATACTGTAATACGCTCTGCTATCACGGTAAGTTGTTGCCTAAAAGAGGGCGTGAAGA
GAGCAATTTAATGCCCGCAATGGGGTATCTCCATATTGATGGTAAAGGAGAGCTGGCAAGTAGTGGAAGTCGATATAATT
TGCTTGAGGCTGAAACGATAGCGGTCTGGTTGGCAGAGAACCAGCAAAATATTGAAGCGCATTACGGTAAATCGCTTCAT
GAAGTTGTCGGTATTGTGACGCCTTTTAGCGCTCAGGTATCCACTATCAAACAGGTGCTGGGCAAACAAGATATCAGTAC
AGGCACGAATGAAAAGTCGCTCACAGTGGGCACCGTGCACTCTCTTCAGGGAGCGGAAAGAGCGATTGTGATATTCTCGC
CAGTCTATTCAAAACATGAAGACGGCGGGTTTATTGATAGCGATAACAGCATGCTGAATGTTGCAGTCTCCCGTGCGAAG
GACAGTTTTCTGGTCTTCGGCGATATGGACCTGTTTGAGGTCCAGCCAGCCTCATCGCCACGGGGATTACTGGCAAAATA
CCTCTTTGAGTCAGAGAAGAATGCGCTCTCTTTTGATTATAAAGAGCGTAAGGATTTAAAAACCGCCGGGACCAAAATCT
ACACACTTCATGGTGTGGAGCAACATGATAATTTCCTGAATCAGACATTTGAAAATACCAGTAAACACATCACGATAATT
TCTCCATGGCTGACCTGGCAAAGGCTGGAGCAAACCGGTTTTCTTGATTCCATGATTGCGGCGTGTTCACGTGGAATTAA
CGTCACGATAGTCACTGACAGAAGCTACAACACTGAACATAATGATTTTGAGAAGCGAAAAGAGAAGCAGCAGAACTTTA
AAGCGGCGCTGGAGAAACTGAATGCGCTGGGTATTGCTACAAAGCTGGTAAACCGTGTTCATAGCAAAATTGTTATTGGT
GATGATGGTTTGCTGTGTGTGGGATCGTTCAACTGGTTTAGTGCGACACGGGAAGCGCGATATGAACGATACGATACATC
AATGGTTTATTGCGGTGATAACCTGAAGGGTGAGATTGAGGCTATTTATAATAGTCTTGAGAGGCGTCAGGTTTAG

Protein sequence :
MDENALGFASYWRNSLADAESGKGSFKRKDAQNFTHWHGIAAGRLDEAIVSKFFEGEKDDVETVDVILRPKVYFRLLQHG
KDRSAGAPDIVTPIVTPALLSREGFLYPTPATSIPRDLLEPLPKGAFSIGEIGQYDKYKTTHTTFSINFDDSVDKTAETD
EEREARYAALQQEWRQYLYDSERLLKSVAGDWIEKPEQYELAEHGYIVKTAQSGGASSHILSLYDHLLVCNKDVPLFNRF
ASREVHAAESLLAPGAKFSDRLGHSGDKFPLAKAQRDALSHFLDARHGDILAVNGPPGTGKTTLVLSIIATQWARAALEK
SEPPVIIATSTNNQAVTNIIEAFGKDFSQGSGAMAGRWLPELKSFGAYFPSSSRKAEAAKKYQTEDFFNQVESKEYVEDA
LLFYLEKAKAAFPGKECSSPEKVIELLHGQLAAKSEQLIRLNATWQTLSQIRAARELIANDIEQYLDNLNKLLSGQEQKV
TLLKSAKTEWKKYRAGESLIYSLFSWLPAVRNKRQYQIQLFLEDKLGALIAGNQWSDPETIERNIDGLLNSAEREQTTYR
QQIDSAHEIVLKEQQAVQEWQRLAFDLGYEGDEELSFSQADELADTQIRFPAFLLTTHYWEGRWLMDMASIDDLQDEKKK
KGAKGVTARWQRRMKLTPCVVMTCYMLPGNMQISEHKGQRKFEKSYLYDFADLLIVDEAGQVLPEVAAASFALAKKALVI
GDTEQIPPIWSIAPAIDVGNMLAEKILSGSTQEEITEKYTAIADLGKSAASGSVMKIAQFASRYQYDPELARGMYLYEHR
RCYDNIIGYCNTLCYHGKLLPKRGREESNLMPAMGYLHIDGKGELASSGSRYNLLEAETIAVWLAENQQNIEAHYGKSLH
EVVGIVTPFSAQVSTIKQVLGKQDISTGTNEKSLTVGTVHSLQGAERAIVIFSPVYSKHEDGGFIDSDNSMLNVAVSRAK
DSFLVFGDMDLFEVQPASSPRGLLAKYLFESEKNALSFDYKERKDLKTAGTKIYTLHGVEQHDNFLNQTFENTSKHITII
SPWLTWQRLEQTGFLDSMIAACSRGINVTIVTDRSYNTEHNDFEKRKEKQQNFKAALEKLNALGIATKLVNRVHSKIVIG
DDGLLCVGSFNWFSATREARYERYDTSMVYCGDNLKGEIEAIYNSLERRQV