Name : S4050 (S4050)
Accession : NP_839218.2
PAI name : SHI-2
PAI accession : NC_004741_P2
Strain : Shigella flexneri 2002017
Virulence or Resistance: Not determined
Product : insertion element IS2 transposase InsD
Function : -
Note : IS2 OrfB; forms an overlapping reading frame with orfA; may form a fusion protein OrfAB due to ribosomal frameshifting; in some cases OrfB is itself expressed; both OrfA and OrfAB bind terminal inverted repeats
Homologs in the searched genomes : 604 hits ( 590 protein-level, 14 DNA-level )
Publication :
-Wei,J., Goldberg,M.B., Burland,V., Venkatesan,M.M., Deng,W., Fournier,G., Mayhew,G.F., Plunkett,G. III, Rose,D.J., Darling,A., Mau,B., Perna,N.T., Payne,S.M., Runyen-Janecky,L.J., Zhou,S., Schwartz,D.C. and Blattner,F.R., "Complete genome sequence and comparative genomics of Shigella flexneri serotype 2a strain 2457T", Infect. Immun. 71 (5), 2775-2786 (2003) PUBMED 12704152 REMARK Erratum:[Infect Immun. 2003 Jul;71(7):4223].
-Wei,J., Goldberg,M.B., Burland,V., Venkatesan,M.M., Deng,W., Fournier,G., Mayhew,G.F., Plunkett,G. III, Rose,D.J., Darling,A., Mau,B., Perna,N.T., Payne,S.M., Runyen-Janecky,L.J., Zhou,S., Schwartz,D.C. and Blattner,F.R., "Direct Submission", Submitted (23-APR-2003) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA.
-Wei,J., Goldberg,M.B., Burland,V., Venkatesan,M.M., Deng,W., Fournier,G., Mayhew,G.F., Plunkett,G. III, Rose,D.J., Darling,A., Mau,B., Perna,N.T., Payne,S.M., Runyen-Janecky,L.J., Zhou,S., Schwartz,D.C. and Blattner,F.R., "Direct Submission", Submitted (13-JUN-2002) Genetics Laboratory, University of Wisconsin - Madison, 445 Henry Mall, Madison, WI 53706, USA.
| DNA sequence : |  |
GTGGATAGCGCACGCGCCCTTATTGCCCGGGGATGGGGAGTAAGCTTAGTCAGCCGTTGTCTCCGGGTGTCGCGTGCGCA
GTTGCACGTCATTCTCAGACGAACCGATGACTGGATGGATGGCCGCCGCAGTCGTCACACTGATGATACGGATGTGCTTC
TCCGTATACACCATGTTATCGGAGAGCTGCCCACGTATGGTTATCGTCGGGTATGGGCGCTGCTTCGCAGACAGGCAGAA
CTTGATGGTATGCCTGCGATCAATGCCAAACGTGTTTACCGGCTCATGCGCCAGAATGCGCTGTTGCTTGAGCGAAAACC
TGCTGTACCGCCATCGAAACGGGCACATACAGGCAGAGTGGCCGTGAAAGAAAGCAATCAGCGATGGTGCTCTGACGGGT
TCGAGTTCTGCTGTGATAACGGAGAGAGACTGCGTGTCACGTTCGCGCTGGACTGCTGTGATCGTGAGGCACTGCACTGG
GCGGTGACTACCGGCGGCTTCAACAGTGAAACAGTACAGGACGTCATGCTGGGAGCGGTGGAACGCCGCTTCGGCAACGA
TCTTCCGTCGTCTCCAGTGGAGTGGCTGACGGATAATGGTTCATGCTACCGGGCTAATGAAACACGCCAGTTCGCCCGGA
TGTTGGGACTTGAACCGAAGAACACGGCGGTGCGGAGTCCGGAGAGTAACGGAATAGCAGAGAGCTTCGTGAAAACGATA
AAGCGTGACTACATCAGTATCATGCCCAAACCAGACGGGTTAACGGCAGCAAAGAACCTTGCAGAGGCGTTCGAGCATTA
TAACGAATGGCATCCGCATAGTGCGCTGGGTTATCGCTCGCCACGGGAATATCTGCGGCAGCGGGCTTGTAATGGGTTAA
GTGATAACAGATGTCTGGAAATATAG
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| Protein sequence : | |
MDSARALIARGWGVSLVSRCLRVSRAQLHVILRRTDDWMDGRRSRHTDDTDVLLRIHHVIGELPTYGYRRVWALLRRQAE
LDGMPAINAKRVYRLMRQNALLLERKPAVPPSKRAHTGRVAVKESNQRWCSDGFEFCCDNGERLRVTFALDCCDREALHW
AVTTGGFNSETVQDVMLGAVERRFGNDLPSSPVEWLTDNGSCYRANETRQFARMLGLEPKNTAVRSPESNGIAESFVKTI
KRDYISIMPKPDGLTAAKNLAEAFEHYNEWHPHSALGYRSPREYLRQRACNGLSDNRCLEI
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