PAI Gene Information


Name : VC0395_A1367 (VC0395_A1367)
Accession : YP_001217310.1
PAI name : VPI-2
PAI accession : NC_009457_P3
Strain : Vibrio cholerae IEC224
Virulence or Resistance: Not determined
Product : DNA methylase HsdM
Function : -
Note : identified by match to protein family HMM PF02384
Homologs in the searched genomes :   71 hits    ( 71 protein-level )  
Publication :
    -Feng,L., Reeves,P.R., Lan,R., Ren,Y., Gao,C., Zhou,Z., Ren,Y., Cheng,J., Wang,W., Wang,J., Qian,W., Li,D. and Wang,L., "A recalibrated molecular clock and independent origins for the cholera pandemic clones", PLoS ONE 3 (12), E4053 (2008) PUBMED 19115014.

    -Feng,L., Reeves,P.R., Lan,R., Ren,Y., Gao,C., Zhou,Z., Ren,Y., Cheng,J., Wang,W., Wang,J., Qian,W., Li,D. and Wang,L., "Direct Submission", Submitted (18-MAY-2007) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA.

    -Heidelberg,J., "Direct Submission", Submitted (16-MAR-2007) The Institute for Genomic Research, 9712 Medical Center Drive, Rockville, MD 20850, USA.


DNA sequence :
ATGGACCACTCAGTACATAACAAACTCGTTTCATTTATTTGGTCGATTGCCGACGACTGTCTTCGTGATGTCTATGTTCG
TGGTAAATACCGCGACGTTATCTTGCCTATGGTGGTGCTACGCCGTCTGGATACGCTTTTGGAGCCATCAAAAGAAGCAG
TACTGGAAGAAGTCAGATTCCAAAAAGAAGAGATGAATGAAATTGAGCTTGATGACGCACCATTATGCGCTACATCAGGT
TATGTGTTCTACAACACGTCCAAGTGGACTCTGCAAACGCTATTCAGTACAGCGACTAACAACCAACAGATTCTGCTGGC
TAACTTCGAAGATTACCTCAACGGTTTTAGCGAAAACGTAAAAGAGATTGTTGAGTGTTTTAACCTGAAAGCCCAAATCC
GTCACATGGCAGGGAAAGACGTTCTGCTAGATGTGGTTGAGAAATTCGTCTCGCCGTACATCAACTTAACGCCAGCGGTT
AAAGAAGATCCTGAGGGTAACAAACTACCAGCACTCAGCAACCTTGGTATGGGCTATGTATTTGAAGAATTGATTCGTAA
GTTCAACGAAGAGAACAACGAAGAGGCGGGGGAGCACTTTACTCCGCGTGAAGTGATCGAGCTGATGACGCACCTTGTTT
TCGATCCAATCAAAGATAACTTGCCACTTTCTATCACAGTGTATGACCCAGCATGTGGTAGTGGCGGTATGCTGACAGAA
ACGCAAAACTTTGTTGAAGAGAAATACCCAGCATCAAACCGTGATATCTACCTTTACGGTAAAGAGATCAACGATGAGAC
TTACGCTATCTGTAAGTCAGATATGATGATCAAAGGTAACAACCCAGAAAACATCCGTGTAGGTTCAACCCTTTCCACTG
ACGAATTCTCATCTAATCGCTTCGATTTCATGCTCTCTAACCCGCCTTATGGTAAGAGCTGGGCGAGTGAGCAAAAGCAC
ATCAAAGAAGGCAAAGAAGTCGTTGATGGTCGCTTTAAAGTGAAGTTAAAAGATTACTGGGGTGTAGAGAGCGAGCAAGA
AGCGATACCACGCTCAAGTGATGGCCAGTTACTGTTCCTGATGGAAATGGTCACCAAAATGAAGTCGCCGCAAGACAGCC
CATTGGGTTCACGCATTGCGTCCGTTCACAATGGTTCAAGCTTGTTTACCGGTGATGCGGGTAGTGGTGAAAGTAATATT
CGTCGTTTCATCATAGAAAATGACATGCTGGATGCGATTGTTCAGTTGCCAAACAACCTGTTCTACAACACGGGTATTAC
CACGTACATCTGGCTGCTCAATAACAACAAACCTGAAAATCGCCAAGGCAAAGTGCAGCTGATTGATGCTAGCTTACTGT
TCCGTAAGTTGCGTAAGAACTTGGGTAATAAAAACTGCGAATTTTCGCCAGAGCACATTGCGGAAATTGTCTCGACCTAT
CTTGAGAATCAATCTGTTGAACGTGCTATTGATGAGAAAGGCGATCCGGTCGGTATTGCCGCGCAAGTATTCAAGAACCA
AGATTTTGGTTACTACAAAGTCAATATTGAGCGCCCAGATCGCCGAAATGCCCAATTCCGCGCTGACTTAATTGAGCCGT
TACGTTTTGAAAACTCACAGCGTGAAGTCATGGAGTACTTGTACGCCGAATATGGCGAGCAAGTCTATGACGCAGGTTTT
GTTAAAGGGATTGAAAAAGAGATCACCAAGTGGTGTGAAGAAAATGATATCAGCCTAAACAAAGCGGCAAAAACCAAGTT
GCTGGATACGAAAAACTGGATTAAACAACGCACACTGGTGAATGTAGCGAGTCAATTACACAAAAAGATCGGTGACGAAG
TTTACAACGACTTTAACCAGTTCAAACAATTAGTAGATGCAGAACTTACATCACTCGGCCTTAAGCTTTCAGCACCAGAA
AAGAAAGCCATCTTGGATGCGGTAAGCTGGTATGACGAAAATGCAGAAAAAGTCATCAAGAAAGTCGCCAAGCTAAAGCA
AGATAAGTTAGACGAACTGCTAGAAAACTACGAATGTGAACTGCAAGATTTGCCAGATTTCGGGTACTACCCAACGGGCA
ACCACAACGAGTTCGTGACTTATGAATCAAGTTCAGACTTGCGTGATAGCGAATCCGTTCCACTTGAGCAAAGCATTTAC
CAATACTTCCTTGATGAAGTAAAGCCGCATGTAGATGAAGCTTGGATAAATCTTGAATCAGTCAAGATTGGTTATGAGAT
CAGCTTTAACAAGTACTTCTATCGCCATAAGCCACTGCGCTCAATGGATGAGGTCGCTGGTGACATTATTGCGCTTGAAC
AAAAAGCGGAAGGCTTAATTGCTGACATTTTGGGCATCTCTGTGGCTAAGGTTCAGGGGTAA

Protein sequence :
MDHSVHNKLVSFIWSIADDCLRDVYVRGKYRDVILPMVVLRRLDTLLEPSKEAVLEEVRFQKEEMNEIELDDAPLCATSG
YVFYNTSKWTLQTLFSTATNNQQILLANFEDYLNGFSENVKEIVECFNLKAQIRHMAGKDVLLDVVEKFVSPYINLTPAV
KEDPEGNKLPALSNLGMGYVFEELIRKFNEENNEEAGEHFTPREVIELMTHLVFDPIKDNLPLSITVYDPACGSGGMLTE
TQNFVEEKYPASNRDIYLYGKEINDETYAICKSDMMIKGNNPENIRVGSTLSTDEFSSNRFDFMLSNPPYGKSWASEQKH
IKEGKEVVDGRFKVKLKDYWGVESEQEAIPRSSDGQLLFLMEMVTKMKSPQDSPLGSRIASVHNGSSLFTGDAGSGESNI
RRFIIENDMLDAIVQLPNNLFYNTGITTYIWLLNNNKPENRQGKVQLIDASLLFRKLRKNLGNKNCEFSPEHIAEIVSTY
LENQSVERAIDEKGDPVGIAAQVFKNQDFGYYKVNIERPDRRNAQFRADLIEPLRFENSQREVMEYLYAEYGEQVYDAGF
VKGIEKEITKWCEENDISLNKAAKTKLLDTKNWIKQRTLVNVASQLHKKIGDEVYNDFNQFKQLVDAELTSLGLKLSAPE
KKAILDAVSWYDENAEKVIKKVAKLKQDKLDELLENYECELQDLPDFGYYPTGNHNEFVTYESSSDLRDSESVPLEQSIY
QYFLDEVKPHVDEAWINLESVKIGYEISFNKYFYRHKPLRSMDEVAGDIIALEQKAEGLIADILGISVAKVQG