PAI Gene Information


Name : SAS1735 (SAS1735)
Accession : YP_043851.1
PAI name : vSa_beta
PAI accession : NC_002953_P2
Strain : Staphylococcus aureus 04-02981
Virulence or Resistance: Virulence
Product : serine protease
Function : -
Note : C-terminus is similar to the C-terminal regions of Staphylococcus aureus exfoliative toxin A precursor Eta SWALL:ETA_STAAU (SWALL:P09331) (280 aa) fasta scores: E(): 2.3e-11, 32.7% id in 211 aa, and to Staphylococcus hyicus exfoliative toxin B SWALL:Q9KWH
Homologs in the searched genomes :   182 hits    ( 182 protein-level )  
Publication :
    -Holden,M.T.G., "Direct Submission", Submitted (23-JUN-2004) Submitted on behalf of the Pathogen Sequencing Unit, Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, E-mail: mh3@sanger.ac.uk.

    -Holden,M.T.G., Feil,E.J., Lindsay,J.A., Peacock,S.J., Day,N.P.J., Enright,M.C., Foster,T.J., Moore,C.E., Hurst,L., Atkin,R., Barron,A., Bason,N., Bentley,S.D., Chillingworth,C., Chillingworth,T., Churcher,C., Clark,L., Corton,C., Cronin,A., Doggett,J., Do, "Complete genomes of two clinical Staphylococcus aureus strains: Evidence for the rapid evolution of virulence and drug resistance", Proc. Natl. Acad. Sci. U.S.A. 101 (26), 9786-9791 (2004) PUBMED 15213324.

    -Holden,M.T.G., Feil,E.J., Lindsay,J.A., Peacock,S.J., Day,N.P.J., Enright,M.C., Foster,T.J., Moore,C.E., Hurst,L., Atkin,R., Barron,A., Bason,N., Bentley,S.D., Chillingworth,C., Chillingworth,T., Churcher,C., Clark,L., Corton,C., Cronin,A., Doggett,J., Do, "Direct Submission", Submitted (11-SEP-2004) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA.


DNA sequence :
ATGAACAAAAACGTAGTCATCAAGAGTTTAGCAGCATTAACAATTTTAACATCTGTAACAGGTATTGGAATAACATTGGT
TGAGGAAGTACAACAAACTGCCAAAGCAGAAAATAATGTCACAAAAGTTAAAGATACAAATATTTTTCCATATACTGGTG
TAGTTGCTTTTAAAAGTGCAACTGGATTTGTAGTTGGAAAGAATACTATTTTAACAAATAAACATGTGTCGAAAAATTAC
AAAGTGGGCGATAGAATTACTGCACATCCAAATAGTGATAAAGGTAATGGTGGTATTTATTCGATTAAAAAGATTATTAA
TTATCCAGGTAAAGAAGATGTATCAGTCATTCAAGTTGAAGAGCGTGCAATAGAACGTGGACCAAAAGGCTTTAATTTTA
ATGATAATGTAACGCCATTCAAATATGCGGCAGGGGCTAAAGCTGGTGAGCGAATTAAAGTGATTGGTTATCCACACCCA
TACAAAAATAAATATGTTTTATATGAGTCAACTGGCCCTGTGATGTCAGTAGAAGGTAGCAGTATTGTATATTCAGCGCA
TACTGAAAGCGGAAACTCTGGATCACCTGTATTAAACAGCAACAACGAATTAGTTGGTATTCATTTTGCTTCTGATGTAA
AAAATGATGATAACAGAAATGCATATGGCGTCTACTTTACACCAGAAATTAAAAAATTCATTGCAGAAAACATAGATAAA
TAA

Protein sequence :
MNKNVVIKSLAALTILTSVTGIGITLVEEVQQTAKAENNVTKVKDTNIFPYTGVVAFKSATGFVVGKNTILTNKHVSKNY
KVGDRITAHPNSDKGNGGIYSIKKIINYPGKEDVSVIQVEERAIERGPKGFNFNDNVTPFKYAAGAKAGERIKVIGYPHP
YKNKYVLYESTGPVMSVEGSSIVYSAHTESGNSGSPVLNSNNELVGIHFASDVKNDDNRNAYGVYFTPEIKKFIAENIDK