PAI Gene Information


Name : SACOL1166 (SACOL1166)
Accession : YP_186029.1
PAI name : vSa_gamma
PAI accession : NC_002951_P3
Strain : Staphylococcus aureus 04-02981
Virulence or Resistance: Not determined
Product : formyl peptide receptor-like 1 inhibitory protein
Function : -
Note : FLIPr; secreted protein that blocks the formyl peptide receptor-like 1 (FPRL1) found in neutrophils, monocytes, B cells, and NK cells; inhibits the binding of chemoattractants (such as formylated peptides) to FPRL1, which initiates the phagocyte mobilizat
Homologs in the searched genomes :   38 hits    ( 37 protein-level,   1 DNA-level )  
Publication :
    -Gill,S.R., Fouts,D.E., Archer,G.L., Mongodin,E.F., Deboy,R.T., Ravel,J., Paulsen,I.T., Kolonay,J.F., Brinkac,L., Beanan,M., Dodson,R.J., Daugherty,S.C., Madupu,R., Angiuoli,S.V., Durkin,A.S., Haft,D.H., Vamathevan,J., Khouri,H., Utterback,T., Lee,C., Dimi, "Insights on evolution of virulence and resistance from the complete genome analysis of an early methicillin-resistant Staphylococcus aureus strain and a biofilm-producing methicillin-resistant Staphylococcus epidermidis strain", J. Bacteriol. 187 (7), 2426-2438 (2005) PUBMED 15774886.

    -Gill,S.R., Fouts,D.E., Archer,G.L., Mongodin,E.F., DeBoy,R.T., Ravel,J., Paulsen,I.T., Kolonay,J.F., Dodson,R.J., Durkin,A.S., Brinkac,L., Beanan,M., Daugherty,S.C., Madupu,R., Angiuoli,S.V., Haft,D.H., Vamathevan,J., Khouri,H., Utterback,T., Lee,C., Dimi, "Direct Submission", Submitted (12-NOV-2004) The Institute for Genomic Research, 9712 Medical Center Dr, Rockville, MD 20850, USA.

    -Gill,S.R., Fouts,D.E., Archer,G.L., Mongodin,E.F., DeBoy,R.T., Ravel,J., Paulsen,I.T., Kolonay,J.F., Dodson,R.J., Durkin,A.S., Brinkac,L., Beanan,M., Daugherty,S.C., Madupu,R., Angiuoli,S.V., Haft,D.H., Vamathevan,J., Khouri,H., Utterback,T., Lee,C., Dimi, "Direct Submission", Submitted (08-APR-2002) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA.


DNA sequence :
ATGAAAAAAAATATCACAAAAACTATTATCGCATCTACAGTAATCGCTGCAGGTCTTTTAACTCAAACTAATGATGCTAA
AGCTTTCTTTAGTTATGAATGGAAAGGTTTAGAAATCGCAAAAAATTTAGCAGATCAAGCTAAAAAGGACGATGAACGTA
TTGATAAGTTAATGAAAGAGTCTGATAAAAATCTAACTCCTTACAAAGCTGAAACTGTTAATGATCTGTACCTTATTGTT
AAAAAATTAAGCCAAGGTGATGTGAAGAAAGCAGTTGTCAGAATTAAAGATGGTGGTCCTAGAGATTACTATACTTTTGA
CTTAACTCGTCCTTTAGAAGAGAACAGAAAAAATATTAAAGTTGTTAAAAACGGTGAAATCGACTCGATTACTTGGTATT
AA

Protein sequence :
MKKNITKTIIASTVIAAGLLTQTNDAKAFFSYEWKGLEIAKNLADQAKKDDERIDKLMKESDKNLTPYKAETVNDLYLIV
KKLSQGDVKKAVVRIKDGGPRDYYTFDLTRPLEENRKNIKVVKNGEIDSITWY