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PAthogenisity Island DataBase (PAI DB)

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Homologs of VPI2_0013c gene of EU272902

protein-level

Hit (GenBank Accn)

Product

Source Genome

Eval.

Ident.(%)

1) PAGR_g3657
( YP_005994366.1 )

type III restriction enzyme, res subunit

NC_017554
(Pantoea ananatis PA13)

0.0

2) Sputw3181_1090
( YP_962494.1 )

type III restriction enzyme, res subunit

NC_008750
(Shewanella sp. W3-18-1)

0.0

3) Shewmr7_1787
( YP_737837.1 )

type III restriction enzyme, res subunit

NC_008322
(Shewanella sp. MR-7)

0.0

4) HDN1F_11660
( YP_003810403.1 )

type I restriction-modification system restriction subunit

NC_014366
(gamma proteobacterium HdN1)

0.0

5) HP15_1582
( YP_005885274.1 )

type III restriction enzyme, res subunit

NC_017506
(Marinobacter adhaerens HP15)

0.0

6) amad1_05840
( YP_006976041.1 )

type III restriction enzyme, res subunit

NC_019393
(Alteromonas macleodii AltDE1)

0.0

7) I636_05855
( YP_008183151.1 )

type III restriction enzyme, res subunit

NC_021714
(Alteromonas macleodii Ionian Sea UM4b)

0.0

8) I635_05820
( YP_008179097.1 )

type III restriction enzyme, res subunit

NC_021713
(Alteromonas macleodii Ionian Sea UM7)

0.0

9) CYCME_2461
( YP_008375125.1 )

Type I site-specific restriction-modification system, R (restriction) subunit-related helicase

NC_021917
(Cycloclasticus zancles 7-ME)

0.0

10) hsdR
( YP_001909233.1 )

type I restriction-modification system, restriction subunit

NC_010694
(Erwinia tasmaniensis Et1/99)

0.0

11) Tola_2270
( YP_002893454.1 )

type III restriction protein res subunit

NC_012691
(Tolumonas auensis DSM 9187)

0.0

12) NT01EI_2502
( YP_002933907.1 )

Type III restriction enzyme, res subunit

NC_012779
(Edwardsiella ictaluri 93-146)

0.0

13) hsdR
( YP_005804547.1 )

type I restriction-modification system restriction subunit

NC_017390
(Erwinia pyrifoliae DSM 12163)

0.0

14) EpC_35290
( YP_002650510.1 )

type I restriction-modification system restriction subunit

NC_012214
(Erwinia pyrifoliae Ep1/96)

0.0

15) MEALZ_3679
( YP_004918918.1 )

type III restriction enzyme, res subunit

NC_016112
(Methylomicrobium alcaliphilum 20Z)

0.0

16) Nhal_0754
( YP_003526321.1 )

hypothetical protein

NC_013960
(Nitrosococcus halophilus Nc 4)

0.0

17) CGSHiGG_03090
( YP_001292001.1 )

putative type I site-specific restriction-modification system, R subunit

NC_009567
(Haemophilus influenzae PittGG)

0.0

18) PSPPH_0104
( YP_272415.1 )

type I restriction-modification system restriction subunit

NC_005773
(Pseudomonas syringae 1448A)

0.0

19) hsdR2
( YP_005829019.1 )

type I restriction modification system, restriction enzyme component HsdR2

NC_017452
(Haemophilus influenzae R2846)

0.0

20) CGSHiEE_02750
( YP_001290371.1 )

putative type I site-specific restriction-modification system, R subunit

NC_009566
(Haemophilus influenzae PittEE)

0.0

21) HICON_03820
( YP_004137536.1 )

restriction endonuclease, type I, R subunit

NC_014922
(Haemophilus influenzae F3047)

0.0

22) hsdR2
( YP_005827190.1 )

Probable type I restriction modification system, restriction enzyme component HsdR2

NC_017451
(Haemophilus influenzae R2866)

0.0

23) Runsl_4460
( YP_004657917.1 )

Restriction endonuclease, type I, EcoRI, R subunit/type III

NC_015703
(Runella slithyformis DSM 19594)

0.0

24) FBFL15_1794
( YP_004844088.1 )

putative type I restriction endonuclease

NC_016001
(Flavobacterium branchiophilum FL-15)

0.0

25) hsdR1
( YP_004134742.1 )

type i site-specific restriction-modification system, r subunit

NC_014920
(Haemophilus influenzae F3031)

0.0

26) hsdR1
( YP_247831.1 )

type I site-specific restriction-modification system, R subunit

NC_007146
(Haemophilus influenzae 86-028NP)

0.0

27) Slin_6264
( YP_003391022.1 )

type III restriction protein res subunit

NC_013730
(Spirosoma linguale DSM 74)

0.0

28) Halhy_4891
( YP_004449593.1 )

Restriction endonuclease, type I, EcoRI, R subunit/Type III

NC_015510
(Haliscomenobacter hydrossis DSM 1100)

0.0

29) DDD_0824
( YP_007375972.1 )

type III restriction enzyme, res subunit

NC_020156
(Nonlabens dokdonensis DSW-6)

0.0

30) hsdR
( YP_679520.1 )

restriction enzyme type I helicase subunit; type I restriction enzyme HsdR

NC_008255
(Cytophaga hutchinsonii ATCC 33406)

0.0

31) SGRA_4128
( YP_005324427.1 )

restriction enzyme type I helicase subunit; type I restriction enzyme HsdR

NC_016940
(Saprospira grandis Lewin)

0.0

32) ZPR_4127
( YP_003586627.1 )

type I restriction enzyme HsdR

NC_014041
(Zunongwangia profunda SMA-87)

0.0

33) Fleli_0174
( YP_006432466.1 )

helicase, type I site-specific restriction-modification system restriction subunit

NC_018018
(Flexibacter litoralis DSM 6794)

0.0

34) APA01_43180
( YP_003189484.1 )

type I/III endonuclease restriction R subunit

NC_013211
(Acetobacter pasteurianus IFO 3283)

0.0

35) APA42C_43180
( YP_005479731.1 )

type I/III endonuclease restriction R subunit

NC_017105
(Acetobacter pasteurianus IFO 3283)

0.0

36) APA12_43180
( YP_005485227.1 )

type I/III endonuclease restriction R subunit

NC_017113
(Acetobacter pasteurianus IFO 3283)

0.0

37) APA03_43180
( YP_005485646.1 )

type I/III endonuclease restriction R subunit

NC_017118
(Acetobacter pasteurianus IFO 3283)

0.0

38) APA07_43180
( YP_005488511.1 )

type I/III endonuclease restriction R subunit

NC_017122
(Acetobacter pasteurianus IFO 3283)

0.0

39) APA22_43180
( YP_005491317.1 )

type I/III endonuclease restriction R subunit

NC_017126
(Acetobacter pasteurianus IFO 3283)

0.0

40) APA26_43180
( YP_005491735.1 )

type I/III endonuclease restriction R subunit

NC_017131
(Acetobacter pasteurianus IFO 3283)

0.0

41) APA32_43180
( YP_005500484.1 )

type I/III endonuclease restriction R subunit

NC_017149
(Acetobacter pasteurianus IFO 3283)

0.0

42) CtCNB1_1528
( YP_003277570.1 )

type III restriction enzyme, res subunit

NC_013446
(Comamonas testosteroni CNB-1)

0.0

43) Oscil6304_1849
( YP_007085442.1 )

helicase, type I site-specific restriction-modification system restriction subunit

NC_019693
(Oscillatoria acuminata PCC 6304)

0.0

44) WQG_21420
( YP_007549210.1 )

Type I restriction-modification system restriction subunit

NC_020515
(Bibersteinia trehalosi USDA-ARS-USMARC-192)

0.0

45) BVU_3410
( YP_001300658.1 )

type I restriction enzyme HsdR

NC_009614
(Bacteroides vulgatus ATCC 8482)

0.0

46) Bacsa_0517
( YP_004257587.1 )

Restriction endonuclease, type I, R subunit/Type III

NC_015164
(Bacteroides salanitronis DSM 18170)

0.0

47) LLO_2867
( YP_003456335.1 )

type-1 restriction system, restriction subunit

NC_013861
(Legionella longbeachae NSW150)

0.0

48) GM18_2921
( YP_004199641.1 )

hypothetical protein

NC_014973
(Geobacter sp. M18)

2e-180

49) Dde_1859
( YP_388351.1 )

Restriction endonuclease, type I, EcoRI, R subunit/Type III

NC_007519
(Desulfovibrio alaskensis G20)

2e-178

50) DGo_CA2781
( YP_006262166.1 )

Type I site-specific deoxyribonuclease chain R

NC_017790
(Deinococcus gobiensis I-0)

3e-178

51) MM_2976
( NP_635000.1 )

type I restriction-modification system restriction subunit

NC_003901
(Methanosarcina mazei Go1)

3e-177

52) Nwat_0200
( YP_003759493.1 )

hypothetical protein

NC_014315
(Nitrosococcus watsonii C-113)

8e-177

53) Mhar_1856
( YP_005920836.1 )

Type I site-specific deoxyribonuclease chain R

NC_017527
(Methanosaeta harundinacea 6Ac)

6e-176

54) DESAM_20023
( YP_007324420.1 )

putative type-1 restriction system, restriction subunit

NC_020055
(Desulfovibrio hydrothermalis DSM 14728)

1e-174

55) join
( NP_942394.1 )

type I site-specific deoxyribonuclease chain R

NC_005231
(Synechocystis sp. PCC 6803)

5e-169

56) join
( YP_007453044.1 )

type I site-specific deoxyribonuclease chain R

NC_020288
(Synechocystis sp. PCC 6803)

5e-169

57) Glov_2197
( YP_001952433.1 )

hypothetical protein

NC_010814
(Geobacter lovleyi SZ)

1e-168

58) Tery_4471
( YP_723931.1 )

hypothetical protein

NC_008312
(Trichodesmium erythraeum IMS101)

1e-168

59) Ilyop_1053
( YP_003967182.1 )

hypothetical protein

NC_014632
(Ilyobacter polytropus DSM 2926)

5e-167

60) Ethha_1806
( YP_004092062.1 )

hypothetical protein

NC_014828
(Ethanoligenens harbinense YUAN-3)

1e-166

61) MCA0274
( YP_112808.1 )

type I restriction-modification system, R subunit

NC_002977
(Methylococcus capsulatus Bath)

2e-166

62) MELS_1617
( YP_004766663.1 )

hypothetical protein

NC_015873
(Megasphaera elsdenii DSM 20460)

3e-166

63) BAST_1688
( YP_006865821.1 )

type-1 restriction system, restriction subunit

NC_018720
(Bifidobacterium asteroides PRL2011)

6e-165

64) Thet_1691
( YP_003904563.1 )

hypothetical protein

NC_014538
(Thermoanaerobacter sp. X513)

9e-163

65) Teth514_1218
( YP_001662848.1 )

hypothetical protein

NC_010320
(Thermoanaerobacter sp. X514)

9e-163

66) Belba_0345
( YP_006405763.1 )

helicase, type I site-specific restriction-modification system restriction subunit

NC_018010
(Belliella baltica DSM 15883)

5e-162

67) BN865_13620c
( YP_008473997.1 )

Type I restriction-modification system, restriction subunit R

NC_022132
(Campylobacter coli 76339)

1e-154

68) CJJ81176_0780
( YP_001000448.1 )

type I site-specific deoxyribonuclease chain R

NC_008787
(Campylobacter jejuni 81-176)

2e-153

69) Msil_3575
( YP_002363825.1 )

hypothetical protein

NC_011666
(Methylocella silvestris BL2)

1e-144

70) ICDCCJ07001_731
( YP_004066287.1 )

Type I restriction enzyme R protein N terminal protein (HSDR_N)

NC_014802
(Campylobacter jejuni ICDCCJ07001)

1e-141

71) Clocl_0191
( YP_005044860.1 )

helicase, type I site-specific restriction-modification system restriction subunit

NC_016627
(Clostridium clariflavum DSM 19732)

1e-135

72) BN341_p1050
( YP_007043513.1 )

Type I restriction-modification system,restriction subunit R

NC_019674
(Helicobacter heilmannii ASB1.4)

8e-133

• Sequence Alignments

1) VCM66_1703 in NC_012578


> EU272902|14|G13|167832520|ACA01830.1|Vibrio_cholerae_Amazonia_3509|-|13968..17036|-|VPI2_0013c|type 
I restriction enzyme 
HsdR
Length=1022

 Score = 1587 bits (6027),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 1018/1022 (99%), Positives = 1020/1022 (99%), Gaps = 0/1022 (0%)

Query  1     MVFMVSKTNEQALEAAIEKGLAGICKEELALGEAPLNYNNDLYLIGSPSDFDKQYALDTR  60
             MVFMVSKTNEQALEAAIEKGLAGICKEELALGEAPLNYNNDLYLIGSPSDFDKQYALDTR
Sbjct  1     MVFMVSKTNEQALEAAIEKGLAGICKEELALGEAPLNYNNDLYLIGSPSDFDKQYALDTR  60

Query  61    LFWQFLEDTQASELEKLKRTSPHDWQRKILERFDRMIKRHGVLRLLKKGLDVDDAFLSLM  120
             LFWQFLEDTQASELEKLKRTSPHDWQRKILERFDRMI RHGVLRLLKKGLDVDDAFLSLM
Sbjct  61    LFWQFLEDTQASELEKLKRTSPHDWQRKILERFDRMIMRHGVLRLLKKGLDVDDAFLSLM  120

Query  121   YPAPLASSSEKVKKDFSANLFSVTRQVCYSNANPLEEIDMVLFINGIPLITLELKNPWTG  180
             YPAPLASSSEKVKKDFSANLFSVTRQVCYSNANPLEEIDMVLFINGIPLITLELKNPWTG
Sbjct  121   YPAPLASSSEKVKKDFSANLFSVTRQVCYSNANPLEEIDMVLFINGIPLITLELKNPWTG  180

Query  181   QNAVYHGQKQYRDDRDANQPLLNFARCLVHMAVDTDEVYMTTKLAGKNTFFLPFNKGFNF  240
             QNAVYHGQKQYRDDRDANQPLLNFARCLVHMAVDTDEVYMTTKLAGKNTFFLPFNKGFNF
Sbjct  181   QNAVYHGQKQYRDDRDANQPLLNFARCLVHMAVDTDEVYMTTKLAGKNTFFLPFNKGFNF  240

Query  241   GKGNPINPHGHKTAYLWQEVFRKESIANIIQHFIRLDGSSKKQLDKRTLFFPRYHQMDVV  300
             GKGNPINPHGHKTAYLWQEVFRKESIANIIQHFIRLDGSSKKQLDKRTLFFPRYHQMDVV
Sbjct  241   GKGNPINPHGHKTAYLWQEVFRKESIANIIQHFIRLDGSSKKQLDKRTLFFPRYHQMDVV  300

Query  301   RRLVDHCSVNGVGQTYLIQHSAGSGKSNSITWAAYQLIETYPISDDLPGSRGKEMPLFDS  360
             RRLVDHCSVNGVGQTYLIQHSAGSGKSNSITWAAYQLIETYPISDDLPGSRGKE+PLFDS
Sbjct  301   RRLVDHCSVNGVGQTYLIQHSAGSGKSNSITWAAYQLIETYPISDDLPGSRGKEVPLFDS  360

Query  361   VIVVTDRRLLDKQLRDNIKEFSEVKNIVAPAFKSSELKSALENGKKIIITTIQKFPYIVD  420
             VIVVTDRRLLDKQLRDNIKEFSEVKNIVAPAFKSSELKSALENGKKIIITTIQKFPYIVD
Sbjct  361   VIVVTDRRLLDKQLRDNIKEFSEVKNIVAPAFKSSELKSALENGKKIIITTIQKFPYIVD  420

Query  421   GIADLSDRRFAVIIDEAHSSQDGHNQDKLNEAMGFVSEDVLDKALQSAKNRKMRSNASYF  480
             GIADLSDRRFAVIIDEAHSSQDGHNQDKLNEAMGFVSEDVLDKALQSAKNRKMRSNASYF
Sbjct  421   GIADLSDRRFAVIIDEAHSSQDGHNQDKLNEAMGFVSEDVLDKALQSAKNRKMRSNASYF  480

Query  481   AFTATPKNTTLEKFGQRQADGTYVPFHLYSMKQAIEEGFILDVIANYTTYKSYYEIEKSI  540
             AFTATPKNTTLEKFGQRQADGTYVPFHLYSMKQAIEEGFILDVIANYTTYKSYYEIEKSI
Sbjct  481   AFTATPKNTTLEKFGQRQADGTYVPFHLYSMKQAIEEGFILDVIANYTTYKSYYEIEKSI  540

Query  541   QDNPEFDSKKAQKRLRAYVEASQETIDTKAEIMLEHFIkhvvngkklkgkgkgmvvTQNI  600
             QDNPEFDSKKAQKRLRAYVEASQETIDTKAEIMLEHFIKHVVNGKKLKGKGKGMVVTQNI
Sbjct  541   QDNPEFDSKKAQKRLRAYVEASQETIDTKAEIMLEHFIKHVVNGKKLKGKGKGMVVTQNI  600

Query  601   ESAIRYYRALTRQLNKMGNPFKVAIAFSGSKEVDGIEYTEADINGFPEGDTKDYFDVNYK  660
             ESAIRYYRALT QLNKMGNPFKVAIAFSGSKEVDGIEYTEADINGFPEGDTKDYFDVNYK
Sbjct  601   ESAIRYYRALTIQLNKMGNPFKVAIAFSGSKEVDGIEYTEADINGFPEGDTKDYFDVNYK  660

Query  661   RKEPDSPIPKHVDQDAYRLLVVANKYLTGFDQPKLCAMYVDKKLASVLCVQALSRLNRSA  720
             RKEPDSPIPKHVDQDAYRLLVVANKYLTGFDQPKLCAMYVDKKLASVLCVQALSRLNRSA
Sbjct  661   RKEPDSPIPKHVDQDAYRLLVVANKYLTGFDQPKLCAMYVDKKLASVLCVQALSRLNRSA  720

Query  721   PKYGKKTEDLFVLDFFNSVDDIKTAFDPFYTSTTLSEATDVNVLHELKDDMDDTDVYEWF  780
             PKYGKKTEDLFVLDFFNSVDDIKTAFDPFYTSTTLSEATDVNVLHELKDDMDDT+VYEWF
Sbjct  721   PKYGKKTEDLFVLDFFNSVDDIKTAFDPFYTSTTLSEATDVNVLHELKDDMDDTGVYEWF  780

Query  781   EVEEFNKRFFEGREAQDLSPIIDIAAARFNHELELENEFKVDFKVKAKQFVKIYGQIASI  840
             EVEEFNKRFFEGREAQDLSPIIDIAAARFNHELELENEFKVDFKVKAKQFVKIYGQIASI
Sbjct  781   EVEEFNKRFFEGREAQDLSPIIDIAAARFNHELELENEFKVDFKVKAKQFVKIYGQIASI  840

Query  841   MPYEVVQWEKLFWFLKFLIPKLSVEDPDKEAldslldsvdlssYGLQRVKLNHSIELDDS  900
             MPYEVVQWEKLFWFLKFLIPKLSVEDPDKEALDSLLDSVDLSSYGLQRVKLNHSIELDDS
Sbjct  841   MPYEVVQWEKLFWFLKFLIPKLSVEDPDKEALDSLLDSVDLSSYGLQRVKLNHSIELDDS  900

Query  901   ETELDPQNPNPRGAYGPEAEKDPLDEIIKIFNERWFQGWSATPEEQRVKFVNIAESIRNH  960
             ETELDPQNPNPRGAYGPEAEKDPLDEIIKIFNERWFQGWSATPEEQRVKFVNIAESIRNH
Sbjct  901   ETELDPQNPNPRGAYGPEAEKDPLDEIIKIFNERWFQGWSATPEEQRVKFVNIAESIRNH  960

Query  961   PDFEAKYQNNADPHTRELAFEKMLKEIMLQRRKDELELYKLFAQDPAFKASWTQSMQRMV  1020
             PDFEAKYQNNADPHTRELAFEKMLKEIMLQRRKDELELYKLFAQDPAFKASWTQSMQRMV
Sbjct  961   PDFEAKYQNNADPHTRELAFEKMLKEIMLQRRKDELELYKLFAQDPAFKASWTQSMQRMV  1020

Query  1021  GM  1022
             GM
Sbjct  1021  GM  1022

2) VCD_002605 in NC_012668


> EU272902|14|G13|167832520|ACA01830.1|Vibrio_cholerae_Amazonia_3509|-|13968..17036|-|VPI2_0013c|type 
I restriction enzyme 
HsdR
Length=1022

 Score = 1587 bits (6027),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 1018/1022 (99%), Positives = 1020/1022 (99%), Gaps = 0/1022 (0%)

Query  1     MVFMVSKTNEQALEAAIEKGLAGICKEELALGEAPLNYNNDLYLIGSPSDFDKQYALDTR  60
             MVFMVSKTNEQALEAAIEKGLAGICKEELALGEAPLNYNNDLYLIGSPSDFDKQYALDTR
Sbjct  1     MVFMVSKTNEQALEAAIEKGLAGICKEELALGEAPLNYNNDLYLIGSPSDFDKQYALDTR  60

Query  61    LFWQFLEDTQASELEKLKRTSPHDWQRKILERFDRMIKRHGVLRLLKKGLDVDDAFLSLM  120
             LFWQFLEDTQASELEKLKRTSPHDWQRKILERFDRMI RHGVLRLLKKGLDVDDAFLSLM
Sbjct  61    LFWQFLEDTQASELEKLKRTSPHDWQRKILERFDRMIMRHGVLRLLKKGLDVDDAFLSLM  120

Query  121   YPAPLASSSEKVKKDFSANLFSVTRQVCYSNANPLEEIDMVLFINGIPLITLELKNPWTG  180
             YPAPLASSSEKVKKDFSANLFSVTRQVCYSNANPLEEIDMVLFINGIPLITLELKNPWTG
Sbjct  121   YPAPLASSSEKVKKDFSANLFSVTRQVCYSNANPLEEIDMVLFINGIPLITLELKNPWTG  180

Query  181   QNAVYHGQKQYRDDRDANQPLLNFARCLVHMAVDTDEVYMTTKLAGKNTFFLPFNKGFNF  240
             QNAVYHGQKQYRDDRDANQPLLNFARCLVHMAVDTDEVYMTTKLAGKNTFFLPFNKGFNF
Sbjct  181   QNAVYHGQKQYRDDRDANQPLLNFARCLVHMAVDTDEVYMTTKLAGKNTFFLPFNKGFNF  240

Query  241   GKGNPINPHGHKTAYLWQEVFRKESIANIIQHFIRLDGSSKKQLDKRTLFFPRYHQMDVV  300
             GKGNPINPHGHKTAYLWQEVFRKESIANIIQHFIRLDGSSKKQLDKRTLFFPRYHQMDVV
Sbjct  241   GKGNPINPHGHKTAYLWQEVFRKESIANIIQHFIRLDGSSKKQLDKRTLFFPRYHQMDVV  300

Query  301   RRLVDHCSVNGVGQTYLIQHSAGSGKSNSITWAAYQLIETYPISDDLPGSRGKEMPLFDS  360
             RRLVDHCSVNGVGQTYLIQHSAGSGKSNSITWAAYQLIETYPISDDLPGSRGKE+PLFDS
Sbjct  301   RRLVDHCSVNGVGQTYLIQHSAGSGKSNSITWAAYQLIETYPISDDLPGSRGKEVPLFDS  360

Query  361   VIVVTDRRLLDKQLRDNIKEFSEVKNIVAPAFKSSELKSALENGKKIIITTIQKFPYIVD  420
             VIVVTDRRLLDKQLRDNIKEFSEVKNIVAPAFKSSELKSALENGKKIIITTIQKFPYIVD
Sbjct  361   VIVVTDRRLLDKQLRDNIKEFSEVKNIVAPAFKSSELKSALENGKKIIITTIQKFPYIVD  420

Query  421   GIADLSDRRFAVIIDEAHSSQDGHNQDKLNEAMGFVSEDVLDKALQSAKNRKMRSNASYF  480
             GIADLSDRRFAVIIDEAHSSQDGHNQDKLNEAMGFVSEDVLDKALQSAKNRKMRSNASYF
Sbjct  421   GIADLSDRRFAVIIDEAHSSQDGHNQDKLNEAMGFVSEDVLDKALQSAKNRKMRSNASYF  480

Query  481   AFTATPKNTTLEKFGQRQADGTYVPFHLYSMKQAIEEGFILDVIANYTTYKSYYEIEKSI  540
             AFTATPKNTTLEKFGQRQADGTYVPFHLYSMKQAIEEGFILDVIANYTTYKSYYEIEKSI
Sbjct  481   AFTATPKNTTLEKFGQRQADGTYVPFHLYSMKQAIEEGFILDVIANYTTYKSYYEIEKSI  540

Query  541   QDNPEFDSKKAQKRLRAYVEASQETIDTKAEIMLEHFIkhvvngkklkgkgkgmvvTQNI  600
             QDNPEFDSKKAQKRLRAYVEASQETIDTKAEIMLEHFIKHVVNGKKLKGKGKGMVVTQNI
Sbjct  541   QDNPEFDSKKAQKRLRAYVEASQETIDTKAEIMLEHFIKHVVNGKKLKGKGKGMVVTQNI  600

Query  601   ESAIRYYRALTRQLNKMGNPFKVAIAFSGSKEVDGIEYTEADINGFPEGDTKDYFDVNYK  660
             ESAIRYYRALT QLNKMGNPFKVAIAFSGSKEVDGIEYTEADINGFPEGDTKDYFDVNYK
Sbjct  601   ESAIRYYRALTIQLNKMGNPFKVAIAFSGSKEVDGIEYTEADINGFPEGDTKDYFDVNYK  660

Query  661   RKEPDSPIPKHVDQDAYRLLVVANKYLTGFDQPKLCAMYVDKKLASVLCVQALSRLNRSA  720
             RKEPDSPIPKHVDQDAYRLLVVANKYLTGFDQPKLCAMYVDKKLASVLCVQALSRLNRSA
Sbjct  661   RKEPDSPIPKHVDQDAYRLLVVANKYLTGFDQPKLCAMYVDKKLASVLCVQALSRLNRSA  720

Query  721   PKYGKKTEDLFVLDFFNSVDDIKTAFDPFYTSTTLSEATDVNVLHELKDDMDDTDVYEWF  780
             PKYGKKTEDLFVLDFFNSVDDIKTAFDPFYTSTTLSEATDVNVLHELKDDMDDT+VYEWF
Sbjct  721   PKYGKKTEDLFVLDFFNSVDDIKTAFDPFYTSTTLSEATDVNVLHELKDDMDDTGVYEWF  780

Query  781   EVEEFNKRFFEGREAQDLSPIIDIAAARFNHELELENEFKVDFKVKAKQFVKIYGQIASI  840
             EVEEFNKRFFEGREAQDLSPIIDIAAARFNHELELENEFKVDFKVKAKQFVKIYGQIASI
Sbjct  781   EVEEFNKRFFEGREAQDLSPIIDIAAARFNHELELENEFKVDFKVKAKQFVKIYGQIASI  840

Query  841   MPYEVVQWEKLFWFLKFLIPKLSVEDPDKEAldslldsvdlssYGLQRVKLNHSIELDDS  900
             MPYEVVQWEKLFWFLKFLIPKLSVEDPDKEALDSLLDSVDLSSYGLQRVKLNHSIELDDS
Sbjct  841   MPYEVVQWEKLFWFLKFLIPKLSVEDPDKEALDSLLDSVDLSSYGLQRVKLNHSIELDDS  900

Query  901   ETELDPQNPNPRGAYGPEAEKDPLDEIIKIFNERWFQGWSATPEEQRVKFVNIAESIRNH  960
             ETELDPQNPNPRGAYGPEAEKDPLDEIIKIFNERWFQGWSATPEEQRVKFVNIAESIRNH
Sbjct  901   ETELDPQNPNPRGAYGPEAEKDPLDEIIKIFNERWFQGWSATPEEQRVKFVNIAESIRNH  960

Query  961   PDFEAKYQNNADPHTRELAFEKMLKEIMLQRRKDELELYKLFAQDPAFKASWTQSMQRMV  1020
             PDFEAKYQNNADPHTRELAFEKMLKEIMLQRRKDELELYKLFAQDPAFKASWTQSMQRMV
Sbjct  961   PDFEAKYQNNADPHTRELAFEKMLKEIMLQRRKDELELYKLFAQDPAFKASWTQSMQRMV  1020

Query  1021  GM  1022
             GM
Sbjct  1021  GM  1022

3) VC1765 in NC_002505


> EU272902|14|G13|167832520|ACA01830.1|Vibrio_cholerae_Amazonia_3509|-|13968..17036|-|VPI2_0013c|type 
I restriction enzyme 
HsdR
Length=1022

 Score = 1587 bits (6027),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 1018/1022 (99%), Positives = 1020/1022 (99%), Gaps = 0/1022 (0%)

Query  1     MVFMVSKTNEQALEAAIEKGLAGICKEELALGEAPLNYNNDLYLIGSPSDFDKQYALDTR  60
             MVFMVSKTNEQALEAAIEKGLAGICKEELALGEAPLNYNNDLYLIGSPSDFDKQYALDTR
Sbjct  1     MVFMVSKTNEQALEAAIEKGLAGICKEELALGEAPLNYNNDLYLIGSPSDFDKQYALDTR  60

Query  61    LFWQFLEDTQASELEKLKRTSPHDWQRKILERFDRMIKRHGVLRLLKKGLDVDDAFLSLM  120
             LFWQFLEDTQASELEKLKRTSPHDWQRKILERFDRMI RHGVLRLLKKGLDVDDAFLSLM
Sbjct  61    LFWQFLEDTQASELEKLKRTSPHDWQRKILERFDRMIMRHGVLRLLKKGLDVDDAFLSLM  120

Query  121   YPAPLASSSEKVKKDFSANLFSVTRQVCYSNANPLEEIDMVLFINGIPLITLELKNPWTG  180
             YPAPLASSSEKVKKDFSANLFSVTRQVCYSNANPLEEIDMVLFINGIPLITLELKNPWTG
Sbjct  121   YPAPLASSSEKVKKDFSANLFSVTRQVCYSNANPLEEIDMVLFINGIPLITLELKNPWTG  180

Query  181   QNAVYHGQKQYRDDRDANQPLLNFARCLVHMAVDTDEVYMTTKLAGKNTFFLPFNKGFNF  240
             QNAVYHGQKQYRDDRDANQPLLNFARCLVHMAVDTDEVYMTTKLAGKNTFFLPFNKGFNF
Sbjct  181   QNAVYHGQKQYRDDRDANQPLLNFARCLVHMAVDTDEVYMTTKLAGKNTFFLPFNKGFNF  240

Query  241   GKGNPINPHGHKTAYLWQEVFRKESIANIIQHFIRLDGSSKKQLDKRTLFFPRYHQMDVV  300
             GKGNPINPHGHKTAYLWQEVFRKESIANIIQHFIRLDGSSKKQLDKRTLFFPRYHQMDVV
Sbjct  241   GKGNPINPHGHKTAYLWQEVFRKESIANIIQHFIRLDGSSKKQLDKRTLFFPRYHQMDVV  300

Query  301   RRLVDHCSVNGVGQTYLIQHSAGSGKSNSITWAAYQLIETYPISDDLPGSRGKEMPLFDS  360
             RRLVDHCSVNGVGQTYLIQHSAGSGKSNSITWAAYQLIETYPISDDLPGSRGKE+PLFDS
Sbjct  301   RRLVDHCSVNGVGQTYLIQHSAGSGKSNSITWAAYQLIETYPISDDLPGSRGKEVPLFDS  360

Query  361   VIVVTDRRLLDKQLRDNIKEFSEVKNIVAPAFKSSELKSALENGKKIIITTIQKFPYIVD  420
             VIVVTDRRLLDKQLRDNIKEFSEVKNIVAPAFKSSELKSALENGKKIIITTIQKFPYIVD
Sbjct  361   VIVVTDRRLLDKQLRDNIKEFSEVKNIVAPAFKSSELKSALENGKKIIITTIQKFPYIVD  420

Query  421   GIADLSDRRFAVIIDEAHSSQDGHNQDKLNEAMGFVSEDVLDKALQSAKNRKMRSNASYF  480
             GIADLSDRRFAVIIDEAHSSQDGHNQDKLNEAMGFVSEDVLDKALQSAKNRKMRSNASYF
Sbjct  421   GIADLSDRRFAVIIDEAHSSQDGHNQDKLNEAMGFVSEDVLDKALQSAKNRKMRSNASYF  480

Query  481   AFTATPKNTTLEKFGQRQADGTYVPFHLYSMKQAIEEGFILDVIANYTTYKSYYEIEKSI  540
             AFTATPKNTTLEKFGQRQADGTYVPFHLYSMKQAIEEGFILDVIANYTTYKSYYEIEKSI
Sbjct  481   AFTATPKNTTLEKFGQRQADGTYVPFHLYSMKQAIEEGFILDVIANYTTYKSYYEIEKSI  540

Query  541   QDNPEFDSKKAQKRLRAYVEASQETIDTKAEIMLEHFIkhvvngkklkgkgkgmvvTQNI  600
             QDNPEFDSKKAQKRLRAYVEASQETIDTKAEIMLEHFIKHVVNGKKLKGKGKGMVVTQNI
Sbjct  541   QDNPEFDSKKAQKRLRAYVEASQETIDTKAEIMLEHFIKHVVNGKKLKGKGKGMVVTQNI  600

Query  601   ESAIRYYRALTRQLNKMGNPFKVAIAFSGSKEVDGIEYTEADINGFPEGDTKDYFDVNYK  660
             ESAIRYYRALT QLNKMGNPFKVAIAFSGSKEVDGIEYTEADINGFPEGDTKDYFDVNYK
Sbjct  601   ESAIRYYRALTIQLNKMGNPFKVAIAFSGSKEVDGIEYTEADINGFPEGDTKDYFDVNYK  660

Query  661   RKEPDSPIPKHVDQDAYRLLVVANKYLTGFDQPKLCAMYVDKKLASVLCVQALSRLNRSA  720
             RKEPDSPIPKHVDQDAYRLLVVANKYLTGFDQPKLCAMYVDKKLASVLCVQALSRLNRSA
Sbjct  661   RKEPDSPIPKHVDQDAYRLLVVANKYLTGFDQPKLCAMYVDKKLASVLCVQALSRLNRSA  720

Query  721   PKYGKKTEDLFVLDFFNSVDDIKTAFDPFYTSTTLSEATDVNVLHELKDDMDDTDVYEWF  780
             PKYGKKTEDLFVLDFFNSVDDIKTAFDPFYTSTTLSEATDVNVLHELKDDMDDT+VYEWF
Sbjct  721   PKYGKKTEDLFVLDFFNSVDDIKTAFDPFYTSTTLSEATDVNVLHELKDDMDDTGVYEWF  780

Query  781   EVEEFNKRFFEGREAQDLSPIIDIAAARFNHELELENEFKVDFKVKAKQFVKIYGQIASI  840
             EVEEFNKRFFEGREAQDLSPIIDIAAARFNHELELENEFKVDFKVKAKQFVKIYGQIASI
Sbjct  781   EVEEFNKRFFEGREAQDLSPIIDIAAARFNHELELENEFKVDFKVKAKQFVKIYGQIASI  840

Query  841   MPYEVVQWEKLFWFLKFLIPKLSVEDPDKEAldslldsvdlssYGLQRVKLNHSIELDDS  900
             MPYEVVQWEKLFWFLKFLIPKLSVEDPDKEALDSLLDSVDLSSYGLQRVKLNHSIELDDS
Sbjct  841   MPYEVVQWEKLFWFLKFLIPKLSVEDPDKEALDSLLDSVDLSSYGLQRVKLNHSIELDDS  900

Query  901   ETELDPQNPNPRGAYGPEAEKDPLDEIIKIFNERWFQGWSATPEEQRVKFVNIAESIRNH  960
             ETELDPQNPNPRGAYGPEAEKDPLDEIIKIFNERWFQGWSATPEEQRVKFVNIAESIRNH
Sbjct  901   ETELDPQNPNPRGAYGPEAEKDPLDEIIKIFNERWFQGWSATPEEQRVKFVNIAESIRNH  960

Query  961   PDFEAKYQNNADPHTRELAFEKMLKEIMLQRRKDELELYKLFAQDPAFKASWTQSMQRMV  1020
             PDFEAKYQNNADPHTRELAFEKMLKEIMLQRRKDELELYKLFAQDPAFKASWTQSMQRMV
Sbjct  961   PDFEAKYQNNADPHTRELAFEKMLKEIMLQRRKDELELYKLFAQDPAFKASWTQSMQRMV  1020

Query  1021  GM  1022
             GM
Sbjct  1021  GM  1022

4) VC395_1879 in NC_012582


> EU272902|14|G13|167832520|ACA01830.1|Vibrio_cholerae_Amazonia_3509|-|13968..17036|-|VPI2_0013c|type 
I restriction enzyme 
HsdR
Length=1022

 Score = 1587 bits (6027),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 1018/1022 (99%), Positives = 1020/1022 (99%), Gaps = 0/1022 (0%)

Query  1     MVFMVSKTNEQALEAAIEKGLAGICKEELALGEAPLNYNNDLYLIGSPSDFDKQYALDTR  60
             MVFMVSKTNEQALEAAIEKGLAGICKEELALGEAPLNYNNDLYLIGSPSDFDKQYALDTR
Sbjct  1     MVFMVSKTNEQALEAAIEKGLAGICKEELALGEAPLNYNNDLYLIGSPSDFDKQYALDTR  60

Query  61    LFWQFLEDTQASELEKLKRTSPHDWQRKILERFDRMIKRHGVLRLLKKGLDVDDAFLSLM  120
             LFWQFLEDTQASELEKLKRTSPHDWQRKILERFDRMI RHGVLRLLKKGLDVDDAFLSLM
Sbjct  61    LFWQFLEDTQASELEKLKRTSPHDWQRKILERFDRMIMRHGVLRLLKKGLDVDDAFLSLM  120

Query  121   YPAPLASSSEKVKKDFSANLFSVTRQVCYSNANPLEEIDMVLFINGIPLITLELKNPWTG  180
             YPAPLASSSEKVKKDFSANLFSVTRQVCYSNANPLEEIDMVLFINGIPLITLELKNPWTG
Sbjct  121   YPAPLASSSEKVKKDFSANLFSVTRQVCYSNANPLEEIDMVLFINGIPLITLELKNPWTG  180

Query  181   QNAVYHGQKQYRDDRDANQPLLNFARCLVHMAVDTDEVYMTTKLAGKNTFFLPFNKGFNF  240
             QNAVYHGQKQYRDDRDANQPLLNFARCLVHMAVDTDEVYMTTKLAGKNTFFLPFNKGFNF
Sbjct  181   QNAVYHGQKQYRDDRDANQPLLNFARCLVHMAVDTDEVYMTTKLAGKNTFFLPFNKGFNF  240

Query  241   GKGNPINPHGHKTAYLWQEVFRKESIANIIQHFIRLDGSSKKQLDKRTLFFPRYHQMDVV  300
             GKGNPINPHGHKTAYLWQEVFRKESIANIIQHFIRLDGSSKKQLDKRTLFFPRYHQMDVV
Sbjct  241   GKGNPINPHGHKTAYLWQEVFRKESIANIIQHFIRLDGSSKKQLDKRTLFFPRYHQMDVV  300

Query  301   RRLVDHCSVNGVGQTYLIQHSAGSGKSNSITWAAYQLIETYPISDDLPGSRGKEMPLFDS  360
             RRLVDHCSVNGVGQTYLIQHSAGSGKSNSITWAAYQLIETYPISDDLPGSRGKE+PLFDS
Sbjct  301   RRLVDHCSVNGVGQTYLIQHSAGSGKSNSITWAAYQLIETYPISDDLPGSRGKEVPLFDS  360

Query  361   VIVVTDRRLLDKQLRDNIKEFSEVKNIVAPAFKSSELKSALENGKKIIITTIQKFPYIVD  420
             VIVVTDRRLLDKQLRDNIKEFSEVKNIVAPAFKSSELKSALENGKKIIITTIQKFPYIVD
Sbjct  361   VIVVTDRRLLDKQLRDNIKEFSEVKNIVAPAFKSSELKSALENGKKIIITTIQKFPYIVD  420

Query  421   GIADLSDRRFAVIIDEAHSSQDGHNQDKLNEAMGFVSEDVLDKALQSAKNRKMRSNASYF  480
             GIADLSDRRFAVIIDEAHSSQDGHNQDKLNEAMGFVSEDVLDKALQSAKNRKMRSNASYF
Sbjct  421   GIADLSDRRFAVIIDEAHSSQDGHNQDKLNEAMGFVSEDVLDKALQSAKNRKMRSNASYF  480

Query  481   AFTATPKNTTLEKFGQRQADGTYVPFHLYSMKQAIEEGFILDVIANYTTYKSYYEIEKSI  540
             AFTATPKNTTLEKFGQRQADGTYVPFHLYSMKQAIEEGFILDVIANYTTYKSYYEIEKSI
Sbjct  481   AFTATPKNTTLEKFGQRQADGTYVPFHLYSMKQAIEEGFILDVIANYTTYKSYYEIEKSI  540

Query  541   QDNPEFDSKKAQKRLRAYVEASQETIDTKAEIMLEHFIkhvvngkklkgkgkgmvvTQNI  600
             QDNPEFDSKKAQKRLRAYVEASQETIDTKAEIMLEHFIKHVVNGKKLKGKGKGMVVTQNI
Sbjct  541   QDNPEFDSKKAQKRLRAYVEASQETIDTKAEIMLEHFIKHVVNGKKLKGKGKGMVVTQNI  600

Query  601   ESAIRYYRALTRQLNKMGNPFKVAIAFSGSKEVDGIEYTEADINGFPEGDTKDYFDVNYK  660
             ESAIRYYRALT QLNKMGNPFKVAIAFSGSKEVDGIEYTEADINGFPEGDTKDYFDVNYK
Sbjct  601   ESAIRYYRALTIQLNKMGNPFKVAIAFSGSKEVDGIEYTEADINGFPEGDTKDYFDVNYK  660

Query  661   RKEPDSPIPKHVDQDAYRLLVVANKYLTGFDQPKLCAMYVDKKLASVLCVQALSRLNRSA  720
             RKEPDSPIPKHVDQDAYRLLVVANKYLTGFDQPKLCAMYVDKKLASVLCVQALSRLNRSA
Sbjct  661   RKEPDSPIPKHVDQDAYRLLVVANKYLTGFDQPKLCAMYVDKKLASVLCVQALSRLNRSA  720

Query  721   PKYGKKTEDLFVLDFFNSVDDIKTAFDPFYTSTTLSEATDVNVLHELKDDMDDTDVYEWF  780
             PKYGKKTEDLFVLDFFNSVDDIKTAFDPFYTSTTLSEATDVNVLHELKDDMDDT+VYEWF
Sbjct  721   PKYGKKTEDLFVLDFFNSVDDIKTAFDPFYTSTTLSEATDVNVLHELKDDMDDTGVYEWF  780

Query  781   EVEEFNKRFFEGREAQDLSPIIDIAAARFNHELELENEFKVDFKVKAKQFVKIYGQIASI  840
             EVEEFNKRFFEGREAQDLSPIIDIAAARFNHELELENEFKVDFKVKAKQFVKIYGQIASI
Sbjct  781   EVEEFNKRFFEGREAQDLSPIIDIAAARFNHELELENEFKVDFKVKAKQFVKIYGQIASI  840

Query  841   MPYEVVQWEKLFWFLKFLIPKLSVEDPDKEAldslldsvdlssYGLQRVKLNHSIELDDS  900
             MPYEVVQWEKLFWFLKFLIPKLSVEDPDKEALDSLLDSVDLSSYGLQRVKLNHSIELDDS
Sbjct  841   MPYEVVQWEKLFWFLKFLIPKLSVEDPDKEALDSLLDSVDLSSYGLQRVKLNHSIELDDS  900

Query  901   ETELDPQNPNPRGAYGPEAEKDPLDEIIKIFNERWFQGWSATPEEQRVKFVNIAESIRNH  960
             ETELDPQNPNPRGAYGPEAEKDPLDEIIKIFNERWFQGWSATPEEQRVKFVNIAESIRNH
Sbjct  901   ETELDPQNPNPRGAYGPEAEKDPLDEIIKIFNERWFQGWSATPEEQRVKFVNIAESIRNH  960

Query  961   PDFEAKYQNNADPHTRELAFEKMLKEIMLQRRKDELELYKLFAQDPAFKASWTQSMQRMV  1020
             PDFEAKYQNNADPHTRELAFEKMLKEIMLQRRKDELELYKLFAQDPAFKASWTQSMQRMV
Sbjct  961   PDFEAKYQNNADPHTRELAFEKMLKEIMLQRRKDELELYKLFAQDPAFKASWTQSMQRMV  1020

Query  1021  GM  1022
             GM
Sbjct  1021  GM  1022

5) VC0395_A1363 in NC_009457


> EU272902|14|G13|167832520|ACA01830.1|Vibrio_cholerae_Amazonia_3509|-|13968..17036|-|VPI2_0013c|type 
I restriction enzyme 
HsdR
Length=1022

 Score = 1587 bits (6027),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 1018/1022 (99%), Positives = 1020/1022 (99%), Gaps = 0/1022 (0%)

Query  1     MVFMVSKTNEQALEAAIEKGLAGICKEELALGEAPLNYNNDLYLIGSPSDFDKQYALDTR  60
             MVFMVSKTNEQALEAAIEKGLAGICKEELALGEAPLNYNNDLYLIGSPSDFDKQYALDTR
Sbjct  1     MVFMVSKTNEQALEAAIEKGLAGICKEELALGEAPLNYNNDLYLIGSPSDFDKQYALDTR  60

Query  61    LFWQFLEDTQASELEKLKRTSPHDWQRKILERFDRMIKRHGVLRLLKKGLDVDDAFLSLM  120
             LFWQFLEDTQASELEKLKRTSPHDWQRKILERFDRMI RHGVLRLLKKGLDVDDAFLSLM
Sbjct  61    LFWQFLEDTQASELEKLKRTSPHDWQRKILERFDRMIMRHGVLRLLKKGLDVDDAFLSLM  120

Query  121   YPAPLASSSEKVKKDFSANLFSVTRQVCYSNANPLEEIDMVLFINGIPLITLELKNPWTG  180
             YPAPLASSSEKVKKDFSANLFSVTRQVCYSNANPLEEIDMVLFINGIPLITLELKNPWTG
Sbjct  121   YPAPLASSSEKVKKDFSANLFSVTRQVCYSNANPLEEIDMVLFINGIPLITLELKNPWTG  180

Query  181   QNAVYHGQKQYRDDRDANQPLLNFARCLVHMAVDTDEVYMTTKLAGKNTFFLPFNKGFNF  240
             QNAVYHGQKQYRDDRDANQPLLNFARCLVHMAVDTDEVYMTTKLAGKNTFFLPFNKGFNF
Sbjct  181   QNAVYHGQKQYRDDRDANQPLLNFARCLVHMAVDTDEVYMTTKLAGKNTFFLPFNKGFNF  240

Query  241   GKGNPINPHGHKTAYLWQEVFRKESIANIIQHFIRLDGSSKKQLDKRTLFFPRYHQMDVV  300
             GKGNPINPHGHKTAYLWQEVFRKESIANIIQHFIRLDGSSKKQLDKRTLFFPRYHQMDVV
Sbjct  241   GKGNPINPHGHKTAYLWQEVFRKESIANIIQHFIRLDGSSKKQLDKRTLFFPRYHQMDVV  300

Query  301   RRLVDHCSVNGVGQTYLIQHSAGSGKSNSITWAAYQLIETYPISDDLPGSRGKEMPLFDS  360
             RRLVDHCSVNGVGQTYLIQHSAGSGKSNSITWAAYQLIETYPISDDLPGSRGKE+PLFDS
Sbjct  301   RRLVDHCSVNGVGQTYLIQHSAGSGKSNSITWAAYQLIETYPISDDLPGSRGKEVPLFDS  360

Query  361   VIVVTDRRLLDKQLRDNIKEFSEVKNIVAPAFKSSELKSALENGKKIIITTIQKFPYIVD  420
             VIVVTDRRLLDKQLRDNIKEFSEVKNIVAPAFKSSELKSALENGKKIIITTIQKFPYIVD
Sbjct  361   VIVVTDRRLLDKQLRDNIKEFSEVKNIVAPAFKSSELKSALENGKKIIITTIQKFPYIVD  420

Query  421   GIADLSDRRFAVIIDEAHSSQDGHNQDKLNEAMGFVSEDVLDKALQSAKNRKMRSNASYF  480
             GIADLSDRRFAVIIDEAHSSQDGHNQDKLNEAMGFVSEDVLDKALQSAKNRKMRSNASYF
Sbjct  421   GIADLSDRRFAVIIDEAHSSQDGHNQDKLNEAMGFVSEDVLDKALQSAKNRKMRSNASYF  480

Query  481   AFTATPKNTTLEKFGQRQADGTYVPFHLYSMKQAIEEGFILDVIANYTTYKSYYEIEKSI  540
             AFTATPKNTTLEKFGQRQADGTYVPFHLYSMKQAIEEGFILDVIANYTTYKSYYEIEKSI
Sbjct  481   AFTATPKNTTLEKFGQRQADGTYVPFHLYSMKQAIEEGFILDVIANYTTYKSYYEIEKSI  540

Query  541   QDNPEFDSKKAQKRLRAYVEASQETIDTKAEIMLEHFIkhvvngkklkgkgkgmvvTQNI  600
             QDNPEFDSKKAQKRLRAYVEASQETIDTKAEIMLEHFIKHVVNGKKLKGKGKGMVVTQNI
Sbjct  541   QDNPEFDSKKAQKRLRAYVEASQETIDTKAEIMLEHFIKHVVNGKKLKGKGKGMVVTQNI  600

Query  601   ESAIRYYRALTRQLNKMGNPFKVAIAFSGSKEVDGIEYTEADINGFPEGDTKDYFDVNYK  660
             ESAIRYYRALT QLNKMGNPFKVAIAFSGSKEVDGIEYTEADINGFPEGDTKDYFDVNYK
Sbjct  601   ESAIRYYRALTIQLNKMGNPFKVAIAFSGSKEVDGIEYTEADINGFPEGDTKDYFDVNYK  660

Query  661   RKEPDSPIPKHVDQDAYRLLVVANKYLTGFDQPKLCAMYVDKKLASVLCVQALSRLNRSA  720
             RKEPDSPIPKHVDQDAYRLLVVANKYLTGFDQPKLCAMYVDKKLASVLCVQALSRLNRSA
Sbjct  661   RKEPDSPIPKHVDQDAYRLLVVANKYLTGFDQPKLCAMYVDKKLASVLCVQALSRLNRSA  720

Query  721   PKYGKKTEDLFVLDFFNSVDDIKTAFDPFYTSTTLSEATDVNVLHELKDDMDDTDVYEWF  780
             PKYGKKTEDLFVLDFFNSVDDIKTAFDPFYTSTTLSEATDVNVLHELKDDMDDT+VYEWF
Sbjct  721   PKYGKKTEDLFVLDFFNSVDDIKTAFDPFYTSTTLSEATDVNVLHELKDDMDDTGVYEWF  780

Query  781   EVEEFNKRFFEGREAQDLSPIIDIAAARFNHELELENEFKVDFKVKAKQFVKIYGQIASI  840
             EVEEFNKRFFEGREAQDLSPIIDIAAARFNHELELENEFKVDFKVKAKQFVKIYGQIASI
Sbjct  781   EVEEFNKRFFEGREAQDLSPIIDIAAARFNHELELENEFKVDFKVKAKQFVKIYGQIASI  840

Query  841   MPYEVVQWEKLFWFLKFLIPKLSVEDPDKEAldslldsvdlssYGLQRVKLNHSIELDDS  900
             MPYEVVQWEKLFWFLKFLIPKLSVEDPDKEALDSLLDSVDLSSYGLQRVKLNHSIELDDS
Sbjct  841   MPYEVVQWEKLFWFLKFLIPKLSVEDPDKEALDSLLDSVDLSSYGLQRVKLNHSIELDDS  900

Query  901   ETELDPQNPNPRGAYGPEAEKDPLDEIIKIFNERWFQGWSATPEEQRVKFVNIAESIRNH  960
             ETELDPQNPNPRGAYGPEAEKDPLDEIIKIFNERWFQGWSATPEEQRVKFVNIAESIRNH
Sbjct  901   ETELDPQNPNPRGAYGPEAEKDPLDEIIKIFNERWFQGWSATPEEQRVKFVNIAESIRNH  960

Query  961   PDFEAKYQNNADPHTRELAFEKMLKEIMLQRRKDELELYKLFAQDPAFKASWTQSMQRMV  1020
             PDFEAKYQNNADPHTRELAFEKMLKEIMLQRRKDELELYKLFAQDPAFKASWTQSMQRMV
Sbjct  961   PDFEAKYQNNADPHTRELAFEKMLKEIMLQRRKDELELYKLFAQDPAFKASWTQSMQRMV  1020

Query  1021  GM  1022
             GM
Sbjct  1021  GM  1022

6) O3Y_08545 in NC_016944


> EU272902|14|G13|167832520|ACA01830.1|Vibrio_cholerae_Amazonia_3509|-|13968..17036|-|VPI2_0013c|type 
I restriction enzyme 
HsdR
Length=1022

 Score = 1581 bits (6003),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 1015/1019 (99%), Positives = 1017/1019 (99%), Gaps = 0/1019 (0%)

Query  1     MVSKTNEQALEAAIEKGLAGICKEELALGEAPLNYNNDLYLIGSPSDFDKQYALDTRLFW  60
             MVSKTNEQALEAAIEKGLAGICKEELALGEAPLNYNNDLYLIGSPSDFDKQYALDTRLFW
Sbjct  4     MVSKTNEQALEAAIEKGLAGICKEELALGEAPLNYNNDLYLIGSPSDFDKQYALDTRLFW  63

Query  61    QFLEDTQASELEKLKRTSPHDWQRKILERFDRMIKRHGVLRLLKKGLDVDDAFLSLMYPA  120
             QFLEDTQASELEKLKRTSPHDWQRKILERFDRMI RHGVLRLLKKGLDVDDAFLSLMYPA
Sbjct  64    QFLEDTQASELEKLKRTSPHDWQRKILERFDRMIMRHGVLRLLKKGLDVDDAFLSLMYPA  123

Query  121   PLASSSEKVKKDFSANLFSVTRQVCYSNANPLEEIDMVLFINGIPLITLELKNPWTGQNA  180
             PLASSSEKVKKDFSANLFSVTRQVCYSNANPLEEIDMVLFINGIPLITLELKNPWTGQNA
Sbjct  124   PLASSSEKVKKDFSANLFSVTRQVCYSNANPLEEIDMVLFINGIPLITLELKNPWTGQNA  183

Query  181   VYHGQKQYRDDRDANQPLLNFARCLVHMAVDTDEVYMTTKLAGKNTFFLPFNKGFNFGKG  240
             VYHGQKQYRDDRDANQPLLNFARCLVHMAVDTDEVYMTTKLAGKNTFFLPFNKGFNFGKG
Sbjct  184   VYHGQKQYRDDRDANQPLLNFARCLVHMAVDTDEVYMTTKLAGKNTFFLPFNKGFNFGKG  243

Query  241   NPINPHGHKTAYLWQEVFRKESIANIIQHFIRLDGSSKKQLDKRTLFFPRYHQMDVVRRL  300
             NPINPHGHKTAYLWQEVFRKESIANIIQHFIRLDGSSKKQLDKRTLFFPRYHQMDVVRRL
Sbjct  244   NPINPHGHKTAYLWQEVFRKESIANIIQHFIRLDGSSKKQLDKRTLFFPRYHQMDVVRRL  303

Query  301   VDHCSVNGVGQTYLIQHSAGSGKSNSITWAAYQLIETYPISDDLPGSRGKEMPLFDSVIV  360
             VDHCSVNGVGQTYLIQHSAGSGKSNSITWAAYQLIETYPISDDLPGSRGKE+PLFDSVIV
Sbjct  304   VDHCSVNGVGQTYLIQHSAGSGKSNSITWAAYQLIETYPISDDLPGSRGKEVPLFDSVIV  363

Query  361   VTDRRLLDKQLRDNIKEFSEVKNIVAPAFKSSELKSALENGKKIIITTIQKFPYIVDGIA  420
             VTDRRLLDKQLRDNIKEFSEVKNIVAPAFKSSELKSALENGKKIIITTIQKFPYIVDGIA
Sbjct  364   VTDRRLLDKQLRDNIKEFSEVKNIVAPAFKSSELKSALENGKKIIITTIQKFPYIVDGIA  423

Query  421   DLSDRRFAVIIDEAHSSQDGHNQDKLNEAMGFVSEDVLDKALQSAKNRKMRSNASYFAFT  480
             DLSDRRFAVIIDEAHSSQDGHNQDKLNEAMGFVSEDVLDKALQSAKNRKMRSNASYFAFT
Sbjct  424   DLSDRRFAVIIDEAHSSQDGHNQDKLNEAMGFVSEDVLDKALQSAKNRKMRSNASYFAFT  483

Query  481   ATPKNTTLEKFGQRQADGTYVPFHLYSMKQAIEEGFILDVIANYTTYKSYYEIEKSIQDN  540
             ATPKNTTLEKFGQRQADGTYVPFHLYSMKQAIEEGFILDVIANYTTYKSYYEIEKSIQDN
Sbjct  484   ATPKNTTLEKFGQRQADGTYVPFHLYSMKQAIEEGFILDVIANYTTYKSYYEIEKSIQDN  543

Query  541   PEFDSKKAQKRLRAYVEASQETIDTKAEIMLEHFIkhvvngkklkgkgkgmvvTQNIESA  600
             PEFDSKKAQKRLRAYVEASQETIDTKAEIMLEHFIKHVVNGKKLKGKGKGMVVTQNIESA
Sbjct  544   PEFDSKKAQKRLRAYVEASQETIDTKAEIMLEHFIKHVVNGKKLKGKGKGMVVTQNIESA  603

Query  601   IRYYRALTRQLNKMGNPFKVAIAFSGSKEVDGIEYTEADINGFPEGDTKDYFDVNYKRKE  660
             IRYYRALT QLNKMGNPFKVAIAFSGSKEVDGIEYTEADINGFPEGDTKDYFDVNYKRKE
Sbjct  604   IRYYRALTIQLNKMGNPFKVAIAFSGSKEVDGIEYTEADINGFPEGDTKDYFDVNYKRKE  663

Query  661   PDSPIPKHVDQDAYRLLVVANKYLTGFDQPKLCAMYVDKKLASVLCVQALSRLNRSAPKY  720
             PDSPIPKHVDQDAYRLLVVANKYLTGFDQPKLCAMYVDKKLASVLCVQALSRLNRSAPKY
Sbjct  664   PDSPIPKHVDQDAYRLLVVANKYLTGFDQPKLCAMYVDKKLASVLCVQALSRLNRSAPKY  723

Query  721   GKKTEDLFVLDFFNSVDDIKTAFDPFYTSTTLSEATDVNVLHELKDDMDDTDVYEWFEVE  780
             GKKTEDLFVLDFFNSVDDIKTAFDPFYTSTTLSEATDVNVLHELKDDMDDT+VYEWFEVE
Sbjct  724   GKKTEDLFVLDFFNSVDDIKTAFDPFYTSTTLSEATDVNVLHELKDDMDDTGVYEWFEVE  783

Query  781   EFNKRFFEGREAQDLSPIIDIAAARFNHELELENEFKVDFKVKAKQFVKIYGQIASIMPY  840
             EFNKRFFEGREAQDLSPIIDIAAARFNHELELENEFKVDFKVKAKQFVKIYGQIASIMPY
Sbjct  784   EFNKRFFEGREAQDLSPIIDIAAARFNHELELENEFKVDFKVKAKQFVKIYGQIASIMPY  843

Query  841   EVVQWEKLFWFLKFLIPKLSVEDPDKEAldslldsvdlssYGLQRVKLNHSIELDDSETE  900
             EVVQWEKLFWFLKFLIPKLSVEDPDKEALDSLLDSVDLSSYGLQRVKLNHSIELDDSETE
Sbjct  844   EVVQWEKLFWFLKFLIPKLSVEDPDKEALDSLLDSVDLSSYGLQRVKLNHSIELDDSETE  903

Query  901   LDPQNPNPRGAYGPEAEKDPLDEIIKIFNERWFQGWSATPEEQRVKFVNIAESIRNHPDF  960
             LDPQNPNPRGAYGPEAEKDPLDEIIKIFNERWFQGWSATPEEQRVKFVNIAESIRNHPDF
Sbjct  904   LDPQNPNPRGAYGPEAEKDPLDEIIKIFNERWFQGWSATPEEQRVKFVNIAESIRNHPDF  963

Query  961   EAKYQNNADPHTRELAFEKMLKEIMLQRRKDELELYKLFAQDPAFKASWTQSMQRMVGM  1019
             EAKYQNNADPHTRELAFEKMLKEIMLQRRKDELELYKLFAQDPAFKASWTQSMQRMVGM
Sbjct  964   EAKYQNNADPHTRELAFEKMLKEIMLQRRKDELELYKLFAQDPAFKASWTQSMQRMVGM  1022

7) Vch1786_I1259 in NC_016445


> EU272902|14|G13|167832520|ACA01830.1|Vibrio_cholerae_Amazonia_3509|-|13968..17036|-|VPI2_0013c|type 
I restriction enzyme 
HsdR
Length=1022

 Score = 1581 bits (6003),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 1015/1019 (99%), Positives = 1017/1019 (99%), Gaps = 0/1019 (0%)

Query  1     MVSKTNEQALEAAIEKGLAGICKEELALGEAPLNYNNDLYLIGSPSDFDKQYALDTRLFW  60
             MVSKTNEQALEAAIEKGLAGICKEELALGEAPLNYNNDLYLIGSPSDFDKQYALDTRLFW
Sbjct  4     MVSKTNEQALEAAIEKGLAGICKEELALGEAPLNYNNDLYLIGSPSDFDKQYALDTRLFW  63

Query  61    QFLEDTQASELEKLKRTSPHDWQRKILERFDRMIKRHGVLRLLKKGLDVDDAFLSLMYPA  120
             QFLEDTQASELEKLKRTSPHDWQRKILERFDRMI RHGVLRLLKKGLDVDDAFLSLMYPA
Sbjct  64    QFLEDTQASELEKLKRTSPHDWQRKILERFDRMIMRHGVLRLLKKGLDVDDAFLSLMYPA  123

Query  121   PLASSSEKVKKDFSANLFSVTRQVCYSNANPLEEIDMVLFINGIPLITLELKNPWTGQNA  180
             PLASSSEKVKKDFSANLFSVTRQVCYSNANPLEEIDMVLFINGIPLITLELKNPWTGQNA
Sbjct  124   PLASSSEKVKKDFSANLFSVTRQVCYSNANPLEEIDMVLFINGIPLITLELKNPWTGQNA  183

Query  181   VYHGQKQYRDDRDANQPLLNFARCLVHMAVDTDEVYMTTKLAGKNTFFLPFNKGFNFGKG  240
             VYHGQKQYRDDRDANQPLLNFARCLVHMAVDTDEVYMTTKLAGKNTFFLPFNKGFNFGKG
Sbjct  184   VYHGQKQYRDDRDANQPLLNFARCLVHMAVDTDEVYMTTKLAGKNTFFLPFNKGFNFGKG  243

Query  241   NPINPHGHKTAYLWQEVFRKESIANIIQHFIRLDGSSKKQLDKRTLFFPRYHQMDVVRRL  300
             NPINPHGHKTAYLWQEVFRKESIANIIQHFIRLDGSSKKQLDKRTLFFPRYHQMDVVRRL
Sbjct  244   NPINPHGHKTAYLWQEVFRKESIANIIQHFIRLDGSSKKQLDKRTLFFPRYHQMDVVRRL  303

Query  301   VDHCSVNGVGQTYLIQHSAGSGKSNSITWAAYQLIETYPISDDLPGSRGKEMPLFDSVIV  360
             VDHCSVNGVGQTYLIQHSAGSGKSNSITWAAYQLIETYPISDDLPGSRGKE+PLFDSVIV
Sbjct  304   VDHCSVNGVGQTYLIQHSAGSGKSNSITWAAYQLIETYPISDDLPGSRGKEVPLFDSVIV  363

Query  361   VTDRRLLDKQLRDNIKEFSEVKNIVAPAFKSSELKSALENGKKIIITTIQKFPYIVDGIA  420
             VTDRRLLDKQLRDNIKEFSEVKNIVAPAFKSSELKSALENGKKIIITTIQKFPYIVDGIA
Sbjct  364   VTDRRLLDKQLRDNIKEFSEVKNIVAPAFKSSELKSALENGKKIIITTIQKFPYIVDGIA  423

Query  421   DLSDRRFAVIIDEAHSSQDGHNQDKLNEAMGFVSEDVLDKALQSAKNRKMRSNASYFAFT  480
             DLSDRRFAVIIDEAHSSQDGHNQDKLNEAMGFVSEDVLDKALQSAKNRKMRSNASYFAFT
Sbjct  424   DLSDRRFAVIIDEAHSSQDGHNQDKLNEAMGFVSEDVLDKALQSAKNRKMRSNASYFAFT  483

Query  481   ATPKNTTLEKFGQRQADGTYVPFHLYSMKQAIEEGFILDVIANYTTYKSYYEIEKSIQDN  540
             ATPKNTTLEKFGQRQADGTYVPFHLYSMKQAIEEGFILDVIANYTTYKSYYEIEKSIQDN
Sbjct  484   ATPKNTTLEKFGQRQADGTYVPFHLYSMKQAIEEGFILDVIANYTTYKSYYEIEKSIQDN  543

Query  541   PEFDSKKAQKRLRAYVEASQETIDTKAEIMLEHFIkhvvngkklkgkgkgmvvTQNIESA  600
             PEFDSKKAQKRLRAYVEASQETIDTKAEIMLEHFIKHVVNGKKLKGKGKGMVVTQNIESA
Sbjct  544   PEFDSKKAQKRLRAYVEASQETIDTKAEIMLEHFIKHVVNGKKLKGKGKGMVVTQNIESA  603

Query  601   IRYYRALTRQLNKMGNPFKVAIAFSGSKEVDGIEYTEADINGFPEGDTKDYFDVNYKRKE  660
             IRYYRALT QLNKMGNPFKVAIAFSGSKEVDGIEYTEADINGFPEGDTKDYFDVNYKRKE
Sbjct  604   IRYYRALTIQLNKMGNPFKVAIAFSGSKEVDGIEYTEADINGFPEGDTKDYFDVNYKRKE  663

Query  661   PDSPIPKHVDQDAYRLLVVANKYLTGFDQPKLCAMYVDKKLASVLCVQALSRLNRSAPKY  720
             PDSPIPKHVDQDAYRLLVVANKYLTGFDQPKLCAMYVDKKLASVLCVQALSRLNRSAPKY
Sbjct  664   PDSPIPKHVDQDAYRLLVVANKYLTGFDQPKLCAMYVDKKLASVLCVQALSRLNRSAPKY  723

Query  721   GKKTEDLFVLDFFNSVDDIKTAFDPFYTSTTLSEATDVNVLHELKDDMDDTDVYEWFEVE  780
             GKKTEDLFVLDFFNSVDDIKTAFDPFYTSTTLSEATDVNVLHELKDDMDDT+VYEWFEVE
Sbjct  724   GKKTEDLFVLDFFNSVDDIKTAFDPFYTSTTLSEATDVNVLHELKDDMDDTGVYEWFEVE  783

Query  781   EFNKRFFEGREAQDLSPIIDIAAARFNHELELENEFKVDFKVKAKQFVKIYGQIASIMPY  840
             EFNKRFFEGREAQDLSPIIDIAAARFNHELELENEFKVDFKVKAKQFVKIYGQIASIMPY
Sbjct  784   EFNKRFFEGREAQDLSPIIDIAAARFNHELELENEFKVDFKVKAKQFVKIYGQIASIMPY  843

Query  841   EVVQWEKLFWFLKFLIPKLSVEDPDKEAldslldsvdlssYGLQRVKLNHSIELDDSETE  900
             EVVQWEKLFWFLKFLIPKLSVEDPDKEALDSLLDSVDLSSYGLQRVKLNHSIELDDSETE
Sbjct  844   EVVQWEKLFWFLKFLIPKLSVEDPDKEALDSLLDSVDLSSYGLQRVKLNHSIELDDSETE  903

Query  901   LDPQNPNPRGAYGPEAEKDPLDEIIKIFNERWFQGWSATPEEQRVKFVNIAESIRNHPDF  960
             LDPQNPNPRGAYGPEAEKDPLDEIIKIFNERWFQGWSATPEEQRVKFVNIAESIRNHPDF
Sbjct  904   LDPQNPNPRGAYGPEAEKDPLDEIIKIFNERWFQGWSATPEEQRVKFVNIAESIRNHPDF  963

Query  961   EAKYQNNADPHTRELAFEKMLKEIMLQRRKDELELYKLFAQDPAFKASWTQSMQRMVGM  1019
             EAKYQNNADPHTRELAFEKMLKEIMLQRRKDELELYKLFAQDPAFKASWTQSMQRMVGM
Sbjct  964   EAKYQNNADPHTRELAFEKMLKEIMLQRRKDELELYKLFAQDPAFKASWTQSMQRMVGM  1022

8) VEA_003238 in NC_013456


> EU272902|14|G13|167832520|ACA01830.1|Vibrio_cholerae_Amazonia_3509|-|13968..17036|-|VPI2_0013c|type 
I restriction enzyme 
HsdR
Length=1022

 Score = 1530 bits (5808),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 957/1023 (94%), Positives = 996/1023 (98%), Gaps = 4/1023 (0%)

Query  1     MVSKTNEQALEAAIEKGLAGICREELALGDAPLNYNNELYLVGFPSDFDKQYALDTRFFW  60
             MVSKTNEQALEAAIEKGLAGIC+EELALG+APLNYNN+LYL+G PSDFDKQYALDTR+FW
Sbjct  4     MVSKTNEQALEAAIEKGLAGICKEELALGEAPLNYNNDLYLIGSPSDFDKQYALDTRLFW  63

Query  61    QFLEETQASELDKLKRTSPHDWQRKILERFDRMIKRKGVLSLLKKGLEVDDAFLTLMYPA  120
             QFLE+TQASEL+KLKRTSPHDWQRKILERFDRMI R GVL LLKKGL+VDDAFL+LMYPA
Sbjct  64    QFLEDTQASELEKLKRTSPHDWQRKILERFDRMIMRHGVLRLLKKGLDVDDAFLSLMYPA  123

Query  121   PLVSSSENVKKNFSANIFSVTRQVCYSNANPLEEIDMVLFINGIPLITLELKNKWTGQNA  180
             PL SSSE+VKK+FSAN+FSVTRQVCYSNANPLEEIDMVLFINGIPLITLELKN WTGQNA
Sbjct  124   PLASSSEKVKKDFSANLFSVTRQVCYSNANPLEEIDMVLFINGIPLITLELKNPWTGQNA  183

Query  181   AYHGQNQYRNDRDANQPLLNFARCLVHMTVDTDEVYMTTKLAGKKTFFLPFNKGFNLGKG  240
              YHGQ+QYR+DRDANQPLLNFARCLVHM+VDTDEVYMTTKLAGK+TFFLPFNKGFN+GKG
Sbjct  184   VYHGQKQYRDDRDANQPLLNFARCLVHMAVDTDEVYMTTKLAGKNTFFLPFNKGFNFGKG  243

Query  241   NPTNPHGHKTAYLWQEVFRKESIANIIQHFVRLDGSSKKQLDKRTLFFPRYHQMDVVRRL  300
             NP NPHGHKTAYLWQEVFRKESIANIIQHF+RLDGSSKKQLDKRTLFFPRYHQMDVVRRL
Sbjct  244   NPINPHGHKTAYLWQEVFRKESIANIIQHFIRLDGSSKKQLDKRTLFFPRYHQMDVVRRL  303

Query  301   VDHCSVNGVGQTYLIQHSAGSGKSNSITWAAYQLIETYPISDDLPGSRGKEVPLFDSVIV  360
             VDHCSVNGVGQTYLIQHSAGSGKSNSITWAAYQLIETYPISDDLPGSRGKEVPLFDSVIV
Sbjct  304   VDHCSVNGVGQTYLIQHSAGSGKSNSITWAAYQLIETYPISDDLPGSRGKEVPLFDSVIV  363

Query  361   VTDRRLLDKQLRDNIKEFSEVKNIVAPAFKSSELKSALESGKKIIITTIQKFPFIIDGIA  420
             VTDRRLLDKQLRDNIKEFSEVKNIVAPAFKSSELKSALE+GKKIIITTIQKFP+I+DGIA
Sbjct  364   VTDRRLLDKQLRDNIKEFSEVKNIVAPAFKSSELKSALENGKKIIITTIQKFPYIVDGIA  423

Query  421   DLSDKRFAVIIDEAHSSQSGSAHDNMNRAMGKKEVEELEDAQDKILQAMRSRKMRGNASY  480
             DLSD+RFAVIIDEAHSSQ G  +D++N AMG       ED  DK LQ+ ++RKMR+NASY
Sbjct  424   DLSDRRFAVIIDEAHSSQDGHNQDKLNEAMGFVS----EDVLDKALQSAKNRKMRSNASY  479

Query  481   FAFTATPKNTTLEKFGQRQADGTYAPFHLYSMKQAIEEGFILDVIANYTTYKSYYEIEKS  540
             FAFTATPKNTTLEKFGQRQADGTY PFHLYSMKQAIEEGFILDVIANYTTYKSYYEIEKS
Sbjct  480   FAFTATPKNTTLEKFGQRQADGTYVPFHLYSMKQAIEEGFILDVIANYTTYKSYYEIEKS  539

Query  541   IQDNPEFDSKKAQKRLRAYVEASQETIDTKAEIMLEHFIKHVINgkklkgkgkgMVVTQN  600
             IQDNPEFDSKKAQKRLRAYVEASQETIDTKAEIMLEHFIKHV+NGKKLKGKGKGMVVTQN
Sbjct  540   IQDNPEFDSKKAQKRLRAYVEASQETIDTKAEIMLEHFIKHVVNGKKLKGKGKGMVVTQN  599

Query  601   IESAIRYYRALTRQLDKMGNPFKVAIAFSGTKEVDGIEYTEADLNGFPEGDTKDYFDVNY  660
             IESAIRYYRALT QL+KMGNPFKVAIAFSG+KEVDGIEYTEAD+NGFPEGDTKDYFDVNY
Sbjct  600   IESAIRYYRALTIQLNKMGNPFKVAIAFSGSKEVDGIEYTEADINGFPEGDTKDYFDVNY  659

Query  661   KRKESDSPIPKHVDQDAFRLLVVANKYLTGFDQPKLCAMYVDKKLASVLCVQALSRLNRS  720
             KRKE+DSPIPKHVDQDA+RLLVVANKYLTGFDQPKLCAMYVDKKLASVLCVQALSRLNRS
Sbjct  660   KRKEPDSPIPKHVDQDAYRLLVVANKYLTGFDQPKLCAMYVDKKLASVLCVQALSRLNRS  719

Query  721   APKYGKKTEDLFVLDFFNSVDDIKTAFDPFYTSTTLSEATDVNVLHELKDDMDDTGVYEW  780
             APKYGKKTEDLFVLDFFNSVDDIKTAFDPFYTSTTLSEATDVNVLHELKDDMDDTGVYEW
Sbjct  720   APKYGKKTEDLFVLDFFNSVDDIKTAFDPFYTSTTLSEATDVNVLHELKDDMDDTGVYEW  779

Query  781   FEVEEFNKRFFEGRDAQDLSPIIDIAAARFNHELELENEFKVDFKVKAKQFVKIYGQMAS  840
             FEVEEFNKRFFEGR+AQDLSPIIDIAAARFNHELELENEFKVDFKVKAKQFVKIYGQ+AS
Sbjct  780   FEVEEFNKRFFEGREAQDLSPIIDIAAARFNHELELENEFKVDFKVKAKQFVKIYGQIAS  839

Query  841   IMPYEVVQWEKLFWFLKFLIPKLSVEDPDKEAldslldsvdlssYGLQRVKLNYSIELDD  900
             IMPYEVVQWEKLFWFLKFLIPKLSVEDPDKEALDSLLDSVDLSSYGLQRVKLN SIELDD
Sbjct  840   IMPYEVVQWEKLFWFLKFLIPKLSVEDPDKEALDSLLDSVDLSSYGLQRVKLNHSIELDD  899

Query  901   SETELDPQNPNPRGAHGPESEKDPLDEIIQIFNERWFQGWSATPEEQRVKFVNIAESIRN  960
             SETELDPQNPNPRGA GPE+EKDPLDEII+IFNERWFQGWSATPEEQRVKFVNIAESIRN
Sbjct  900   SETELDPQNPNPRGAYGPEAEKDPLDEIIKIFNERWFQGWSATPEEQRVKFVNIAESIRN  959

Query  961   HPDFEAKYQNNADPHTRELAFEKMLKEIMLQRRKDELELYKLFAQDPAFKASWTQSMQRM  1020
             HPDFEAKYQNNADPHTRELAFEKMLKEIMLQRRKDELELYKLFAQDPAFKASWTQSMQRM
Sbjct  960   HPDFEAKYQNNADPHTRELAFEKMLKEIMLQRRKDELELYKLFAQDPAFKASWTQSMQRM  1019

Query  1021  VGM  1023
             VGM
Sbjct  1020  VGM  1022

9) PAGR_g3657 in NC_017554


> EU272902|14|G13|167832520|ACA01830.1|Vibrio_cholerae_Amazonia_3509|-|13968..17036|-|VPI2_0013c|type 
I restriction enzyme 
HsdR
Length=1022

 Score = 1309 bits (4967),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 793/1022 (78%), Positives = 906/1022 (89%), Gaps = 22/1022 (2%)

Query  1     MVSQTNEQALESTIEKCLVGISAEELKGGLSP-QFSGTGYVIGASSDFNMQYAIDERFFW  59
             MVS+TNEQALE++IEK L GI  EEL  G +P +++   Y+IG++SDF+ QYA+D R+FW
Sbjct  4     MVSKTNEQALEAAIEKGLAGICKEELALGEAPLNYNNDLYLIGSPSDFDKQYALDTRLFW  63

Query  60    KFLEKTQEAELTKLQKNNPADWQRKLLERFDRLIKKHGILHVLKKGLSVDDAHFILLYPA  119
             +FLE TQ +EL KL++ +P DWQRK+LERFDR+I +HG+L++LKKGL VDDA + L+YPA
Sbjct  64    QFLEDTQASELEKLKRTSPHDWQRKILERFDRMIMRHGVLRLLKKGLDVDDAFLSLMYPA  123

Query  120   PLASSSEKVKQNFADNVFSCTRQVRYSVANPLQEIDMVLFINGIPLITLELKNAWTGQTA  179
             PLASSSEKVK++F+ N+FS TRQV YS ANPL+EIDMVLFINGIPLITLELKN+WTGQ A
Sbjct  124   PLASSSEKVKKDFSANLFSVTRQVCYSNANPLEEIDMVLFINGIPLITLELKNPWTGQNA  183

Query  180   RYHGQKQYRDDRDATQPLLTFGRCLVHMAVDTDEVYMTTKLAGKNTFFLPFNKGHNLGQG  239
              YHGQKQYRDDRDA QPLL F+RCLVHMAVDTDEVYMTTKLAGKNTFFLPFNKG N+G+G
Sbjct  184   VYHGQKQYRDDRDANQPLLNFARCLVHMAVDTDEVYMTTKLAGKNTFFLPFNKGFNFGKG  243

Query  240   NPPNPAGHKTAYLWQEIFTKESLANIIQHFVRLDGTSKEPLPKRTLFFPRYHQLDVVRKL  299
             NP NP GHKTAYLWQE+F KES+ANIIQHF+RLDG+SK  L KRTLFFPRYHQ+DVVR+L
Sbjct  244   NPINPHGHKTAYLWQEVFRKESIANIIQHFIRLDGSSKKQLDKRTLFFPRYHQMDVVRRL  303

Query  300   VDHAATHGVGQTYLIQHSAGSGKSNSITWAAYQLIETYPATESEAGGKSLEQPLFDSVIV  359
             VDH + +GVGQTYLIQHSAGSGKSNSITWAAYQLIETYP ++  +G+++ E PLFDSVIV
Sbjct  304   VDHCSVNGVGQTYLIQHSAGSGKSNSITWAAYQLIETYPISDDLPGSRGKEVPLFDSVIV  363

Query  360   VTDRRLLDKQLRDNIKEFSEVKNIIAPAHKSSELKQALENGKKIIITTIQKFPFIIDGIA  419
             VTDRRLLDKQLRDNIKEFSEVKNI+APA KSSELK ALENGKKIIITTIQKFP+I+DGIA
Sbjct  364   VTDRRLLDKQLRDNIKEFSEVKNIVAPAFKSSELKSALENGKKIIITTIQKFPYIVDGIA  423

Query  420   DLSDKRFAVIIDEAHSSQSGSAHDNMNRVMGKAGVEEAEDAQDKILQAMKSRKMRGNASY  479
             DLSD+RFAVIIDEAHSSQ G  +D++N  MG  +    ED  DK LQ+ K+RKMR+NASY
Sbjct  424   DLSDRRFAVIIDEAHSSQDGHNQDKLNEAMGFVS----EDVLDKALQSAKNRKMRSNASY  479

Query  480   LAFTATPKNSTLEKFGERQEDGAFKPLHLYSMKQAIEEGFILDVLANYTTYKSYYEIEKS  539
             +AFTATPKN+TLEKFG+RQ DG++ P+HLYSMKQAIEEGFILDV+ANYTTYKSYYEIEKS
Sbjct  480   FAFTATPKNTTLEKFGQRQADGTYVPFHLYSMKQAIEEGFILDVIANYTTYKSYYEIEKS  539

Query  540   IADNPEFDTKKAQKKLRAYVERSQQTIDTKAEIMLEHFVPHVVNAkklkgkgkgMVVTQN  599
             I DNPEFD+KKAQK+LRAYVE SQ+TIDTKAEIMLEHF+ HVVN+KKLKGKGKGMVVTQN
Sbjct  540   IQDNPEFDSKKAQKRLRAYVEASQETIDTKAEIMLEHFIKHVVNGKKLKGKGKGMVVTQN  599

Query  600   IETAIRYYKAIKRILEEQSNPFKILIAFSGTKEVDGIEYTEADINGFAETDTKDMFDT--  657
             IE+AIRYY+A+   L+  +NPFK+ IAFSG+KEVDGIEYTEADINGF+E DTKD FD   
Sbjct  600   IESAIRYYRALTIQLNKMGNPFKVAIAFSGSKEVDGIEYTEADINGFPEGDTKDYFDVNY  659

Query  658   ---------------DEYRLLVVANKYLTGFDQPKLCAMYVDKKLASVLCVQALSRLNRS  702
                            D YRLLVVANKYLTGFDQPKLCAMYVDKKLASVLCVQALSRLNRS
Sbjct  660   KRKEPDSPIPKHVDQDAYRLLVVANKYLTGFDQPKLCAMYVDKKLASVLCVQALSRLNRS  719

Query  703   APKLGKKTEDLFILDFFNSVEDIQLAFDPFYTATSLSQATDINVLHELKDEMDDVGVYEW  762
             APK GKKTEDLF+LDFFNSV+DI+ AFDPFYT+T+LS+ATD+NVLHELKD+MDD GVYEW
Sbjct  720   APKYGKKTEDLFVLDFFNSVDDIKTAFDPFYTSTTLSEATDVNVLHELKDDMDDTGVYEW  779

Query  763   LEIEEFVIRYFNNEDAQTLSPIIDVAAARFDYELELEPEAKVDFKIKAKQFVKIYGQMAS  822
             +E+EEF  R+F+  +AQ LSPIID+AAARF+ ELELE E KVDFK+KAKQFVKIYGQ+AS
Sbjct  780   FEVEEFNKRFFEGREAQDLSPIIDIAAARFNHELELENEFKVDFKVKAKQFVKIYGQIAS  839

Query  823   IMPYEMVTWEKLFWFLKFLIPKLKVEDPDADAIDELLDSVDLSSYGLQRVKLNHTIKLSD  882
             IMPYE+V WEKLFWFLKFLIPKL VEDPD +A+D LLDSVDLSSYGLQRVKLNH+I L D
Sbjct  840   IMPYEVVQWEKLFWFLKFLIPKLSVEDPDKEALDSLLDSVDLSSYGLQRVKLNHSIELDD  899

Query  883   EEAELDPQNPNPRGAHSSEKEKDPLDEIIRTFNERWFQGWSATPEEQKVKFINIAESIRN  942
              E+ELDPQNPNPRGA ++E EKDPLDEII+ FNERWFQGWSATPEEQ+VKF+NIAESIRN
Sbjct  900   SETELDPQNPNPRGAYGPEAEKDPLDEIIKIFNERWFQGWSATPEEQRVKFVNIAESIRN  959

Query  943   HPDFETKYRNNPDPHNRNLAFEKMLKEIMLQRRKDELELYKLFAGDSAFKASWTQSMQRM  1002
             HPDFE+KY+NN+DPH R+LAFEKMLKEIMLQRRKDELELYKLFA D+AFKASWTQSMQRM
Sbjct  960   HPDFEAKYQNNADPHTRELAFEKMLKEIMLQRRKDELELYKLFAQDPAFKASWTQSMQRM  1019

Query  1003  IG  1004
             +G
Sbjct  1020  VG  1021

10) Sputw3181_1090 in NC_008750


> EU272902|14|G13|167832520|ACA01830.1|Vibrio_cholerae_Amazonia_3509|-|13968..17036|-|VPI2_0013c|type 
I restriction enzyme 
HsdR
Length=1022

 Score = 1293 bits (4905),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 807/1025 (79%), Positives = 909/1025 (89%), Gaps = 26/1025 (2%)

Query  1     MVSQTNEQALESAIEKCLAGISTEELKEGLSQQSLGAG---YFIGAASDFNMQYAIDERF  57
             MVS+TNEQALE+AIEK LAGI  EEL  +L++ +L      Y+IG++SDF+ QYA+D R+
Sbjct  4     MVSKTNEQALEAAIEKGLAGICKEEL--ALGEAPLNYNNDLYLIGSPSDFDKQYALDTRL  61

Query  58    FWQFLQKTQEEELAKLQKNNPSDWQRKLLERFDRlikkhgilhllkkglSVDDAHFNLLY  117
             FWQFL+ TQ  EL KL++ +P DWQRK+LERFDR+I +HG+L+LLKKGL VDDA ++L+Y
Sbjct  62    FWQFLEDTQASELEKLKRTSPHDWQRKILERFDRMIMRHGVLRLLKKGLDVDDAFLSLMY  121

Query  118   PAPLASSSEKVKQNFADNVFSCTRQVRYSMANPLQEIDMVLFINGIPLITLELKNAWTGQ  177
             PAPLASSSEKVK++F+ N+FS TRQV YS ANPL+EIDMVLFINGIPLITLELKN+WTGQ
Sbjct  122   PAPLASSSEKVKKDFSANLFSVTRQVCYSNANPLEEIDMVLFINGIPLITLELKNPWTGQ  181

Query  178   TARYHGQKQYRDDRDATQALLTFGRCLVHMAVDTDEVYMTTKLSGGSTFFLPFNKGHNLG  237
              A YHGQKQYRDDRDA Q+LL F+RCLVHMAVDTDEVYMTTKL+G +TFFLPFNKG N+G
Sbjct  182   NAVYHGQKQYRDDRDANQPLLNFARCLVHMAVDTDEVYMTTKLAGKNTFFLPFNKGFNFG  241

Query  238   QGNPPNPTGHKTAYLWQEVFTKESLANIIQHFVRLDGSSKDPLPKRTLFFPRYHQLDVVR  297
             +GNP NP GHKTAYLWQEVF KES+ANIIQHF+RLDGSSK  L KRTLFFPRYHQ+DVVR
Sbjct  242   KGNPINPHGHKTAYLWQEVFRKESIANIIQHFIRLDGSSKKQLDKRTLFFPRYHQMDVVR  301

Query  298   KLVDHAAQHGVGQTYLIQHSAGSGKSNSITWAAYQLIETYPASSDVAGGKSLEQPLFDSV  357
             +LVDH + +GVGQTYLIQHSAGSGKSNSITWAAYQLIETYP S D++G+++ E PLFDSV
Sbjct  302   RLVDHCSVNGVGQTYLIQHSAGSGKSNSITWAAYQLIETYPISDDLPGSRGKEVPLFDSV  361

Query  358   IVVTDRRLLDKQLRDNIKEFSEVKNIIAPANKSSELKQALENGKKIIITTIQKFPFIIDG  417
             IVVTDRRLLDKQLRDNIKEFSEVKNI+APA KSSELK ALENGKKIIITTIQKFP+I+DG
Sbjct  362   IVVTDRRLLDKQLRDNIKEFSEVKNIVAPAFKSSELKSALENGKKIIITTIQKFPYIVDG  421

Query  418   IADLSDKRFAVIIDEAHSSQSGSAHDNMNRAMGKSEIEEAEDAQDKILQAMKSRKMRGNA  477
             IADLSD+RFAVIIDEAHSSQ G  +D++N AMG      +ED  DK LQ+ K+RKMR+NA
Sbjct  422   IADLSDRRFAVIIDEAHSSQDGHNQDKLNEAMGFV----SEDVLDKALQSAKNRKMRSNA  477

Query  478   SYLAFTATPKNSTLEKFGQRQEDGSFKPFHLYSMKQAIEEGFILDVLANYTTYKSYYEIE  537
             SY+AFTATPKN+TLEKFGQRQ DG++ PFHLYSMKQAIEEGFILDV+ANYTTYKSYYEIE
Sbjct  478   SYFAFTATPKNTTLEKFGQRQADGTYVPFHLYSMKQAIEEGFILDVIANYTTYKSYYEIE  537

Query  538   KSIADNPEFDTKKAQKKLRAYVERSQQTIDTKAEIMLEHFVPHVVNAkklkgkgkgMVVT  597
             KSI DNPEFD+KKAQK+LRAYVE SQ+TIDTKAEIMLEHF+ HVVN+KKLKGKGKGMVVT
Sbjct  538   KSIQDNPEFDSKKAQKRLRAYVEASQETIDTKAEIMLEHFIKHVVNGKKLKGKGKGMVVT  597

Query  598   QNIETAIRYYKAIRRILEEQGNPFKVAIAFSGIKEVDGIEYTEADINGFAESDTKDMFDT  657
             QNIE+AIRYY+A+   L+  GNPFKVAIAFSG KEVDGIEYTEADINGF+E+DTKD FD 
Sbjct  598   QNIESAIRYYRALTIQLNKMGNPFKVAIAFSGSKEVDGIEYTEADINGFPEGDTKDYFDV  657

Query  658   -----------------DEYRLLVVANKYLTGFDQPKLCAMYVDKKLASVLCVQTLSRLN  700
                              D YRLLVVANKYLTGFDQPKLCAMYVDKKLASVLCVQ+LSRLN
Sbjct  658   NYKRKEPDSPIPKHVDQDAYRLLVVANKYLTGFDQPKLCAMYVDKKLASVLCVQALSRLN  717

Query  701   RSAPKWGKKTEDLFVLDFFNSVEDIQSAFDPFYTATSLSQATDINVLHELKDEMDDVGVY  760
             RSAPK GKKTEDLFVLDFFNSV+DI++AFDPFYT+T+LS+ATD+NVLHELKD+MDD GVY
Sbjct  718   RSAPKYGKKTEDLFVLDFFNSVDDIKTAFDPFYTSTTLSEATDVNVLHELKDDMDDTGVY  777

Query  761   EWYEVEDFVTRYFKNEDAQTLSPIIDVAAARFDHELELEAEAKVDFKIKAKQFVKIYGQM  820
             EW+EVE+F  R+F   +AQ LSPIID+AAARF+HELELE E KVDFK+KAKQFVKIYGQ+
Sbjct  778   EWFEVEEFNKRFFEGREAQDLSPIIDIAAARFNHELELENEFKVDFKVKAKQFVKIYGQI  837

Query  821   ASIMPYEMVSWEKLFWFLKFLIPKLKVEDPDADAIDELLDSVDLSSYGLQRVKLNHSIKL  880
             ASIMPYE+V WEKLFWFLKFLIPKL VEDPD +A+D LLDSVDLSSYGLQRVKLNHSI L
Sbjct  838   ASIMPYEVVQWEKLFWFLKFLIPKLSVEDPDKEALDSLLDSVDLSSYGLQRVKLNHSIEL  897

Query  881   SDQEAELDPQNPNPRGAHGGEKETDPLDEIIRTFNERWFQGWSATPEEQKVKFVNIAESI  940
              D E+ELDPQNPNPRGA G E E DPLDEII+ FNERWFQGWSATPEEQ+VKFVNIAESI
Sbjct  898   DDSETELDPQNPNPRGAYGPEAEKDPLDEIIKIFNERWFQGWSATPEEQRVKFVNIAESI  957

Query  941   RNHPDFESKYKNNPDPHNRDLAFEKMLKEIMLQRRKDELELYKLFAGDSAFKASWTQSMQ  1000
             RNHPDFE+KY+NN+DPH R+LAFEKMLKEIMLQRRKDELELYKLFA D+AFKASWTQSMQ
Sbjct  958   RNHPDFEAKYQNNADPHTRELAFEKMLKEIMLQRRKDELELYKLFAQDPAFKASWTQSMQ  1017

Query  1001  RMVGM  1005
             RMVGM
Sbjct  1018  RMVGM  1022

11) Shewmr7_1787 in NC_008322


> EU272902|14|G13|167832520|ACA01830.1|Vibrio_cholerae_Amazonia_3509|-|13968..17036|-|VPI2_0013c|type 
I restriction enzyme 
HsdR
Length=1022

 Score = 1286 bits (4879),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 802/1028 (79%), Positives = 904/1028 (88%), Gaps = 26/1028 (2%)

Query  1     MVSSTNEQALEASIERALTGHCLEDQKAGISDGIVTPYGVNHCGYSSGYSSDFNMQYAID  60
             MVS TNEQALEA+IE++L+G C E+   G      +P   N+  Y  G +SDF+ QYA+D
Sbjct  4     MVSKTNEQALEAAIEKGLAGICKEELALG-----EAPLNYNNDLYLIGSPSDFDKQYALD  58

Query  61    ERFFWQFLQKTQEVELAKLQKNNPSDWQRKLLERFDRlikkhgilhllkkglSVDDAHFN  120
              R+FWQFL+ TQ  EL KL++ +P DWQRK+LERFDR+I +HG+L+LLKKGL VDDA ++
Sbjct  59    TRLFWQFLEDTQASELEKLKRTSPHDWQRKILERFDRMIMRHGVLRLLKKGLDVDDAFLS  118

Query  121   LLYPAPLASSSEKVKQNFADNVFSCTRQVRYSMANPLQEIDMVLFINGIPLITLELKNAW  180
             L+YPAPLASSSEKVK++F+ N+FS TRQV YS ANPL+EIDMVLFINGIPLITLELKN+W
Sbjct  119   LMYPAPLASSSEKVKKDFSANLFSVTRQVCYSNANPLEEIDMVLFINGIPLITLELKNPW  178

Query  181   TGQTARYHGQKQYRDDRDATQPLLTFGRCLVHMAVDTDEVYMTTKLSGGSTFFLPFNKGH  240
             TGQ A YHGQKQYRDDRDA QPLL F+RCLVHMAVDTDEVYMTTKL+G +TFFLPFNKG 
Sbjct  179   TGQNAVYHGQKQYRDDRDANQPLLNFARCLVHMAVDTDEVYMTTKLAGKNTFFLPFNKGF  238

Query  241   NLGQGNPPNPTGHKTAYLWQEVFTKESLANIIQHFVRLDGSSKDPLPKRTLFFPRYHQLD  300
             N+G+GNP NP GHKTAYLWQEVF KES+ANIIQHF+RLDGSSK  L KRTLFFPRYHQ+D
Sbjct  239   NFGKGNPINPHGHKTAYLWQEVFRKESIANIIQHFIRLDGSSKKQLDKRTLFFPRYHQMD  298

Query  301   VVRKLVDHAAQHGVGQTYLIQHSAGSGKSNSITWAAYQLIETYPASSDVAGGKSLEQPLF  360
             VVR+LVDH + +GVGQTYLIQHSAGSGKSNSITWAAYQLIETYP S D++G+++ E PLF
Sbjct  299   VVRRLVDHCSVNGVGQTYLIQHSAGSGKSNSITWAAYQLIETYPISDDLPGSRGKEVPLF  358

Query  361   DSVIVVTDRRLLDKQLRDNIKEFSEVKNIIAPANKSSELKQALENGKKIIITTIQKFPFI  420
             DSVIVVTDRRLLDKQLRDNIKEFSEVKNI+APA KSSELK ALENGKKIIITTIQKFP+I
Sbjct  359   DSVIVVTDRRLLDKQLRDNIKEFSEVKNIVAPAFKSSELKSALENGKKIIITTIQKFPYI  418

Query  421   IDGIADLSDKRFAVIIDEAHSSQSGSAHDNMNRAMGKSEVEEAEDAQDKILQAMKSRKMR  480
             +DGIADLSD+RFAVIIDEAHSSQ G  +D++N AMG      +ED  DK LQ+ K+RKMR
Sbjct  419   VDGIADLSDRRFAVIIDEAHSSQDGHNQDKLNEAMGFV----SEDVLDKALQSAKNRKMR  474

Query  481   GNASYLAFTATPKNSTLEKFGQRQEDGPFKPFHLYSMKQAIEEGFILDVLANYTTYKSYY  540
             +NASY+AFTATPKN+TLEKFGQRQ DG + PFHLYSMKQAIEEGFILDV+ANYTTYKSYY
Sbjct  475   SNASYFAFTATPKNTTLEKFGQRQADGTYVPFHLYSMKQAIEEGFILDVIANYTTYKSYY  534

Query  541   EIEKSIADNPEFDTKKAQKKLRAYVERSQQTIDTKAEIMLEHFVPHVVNAKKLKGKGKAM  600
             EIEKSI DNPEFD+KKAQK+LRAYVE SQ+TIDTKAEIMLEHF+ HVVN+KKLKGKGK+M
Sbjct  535   EIEKSIQDNPEFDSKKAQKRLRAYVEASQETIDTKAEIMLEHFIKHVVNGKKLKGKGKGM  594

Query  601   VVTQNIETAIRYYKAIKRILEEQGNPFKVAIAFSGTKEVDGIEYTEADINGFAESDTKDM  660
             VVTQNIE+AIRYY+A+   L+  GNPFKVAIAFSG+KEVDGIEYTEADINGF+E+DTKD 
Sbjct  595   VVTQNIESAIRYYRALTIQLNKMGNPFKVAIAFSGSKEVDGIEYTEADINGFPEGDTKDY  654

Query  661   FDT-----------------DEYRLLVVANKYLTGFDQPKLCAMYVDKKLASVLCVQTLS  703
             FD                  D YRLLVVANKYLTGFDQPKLCAMYVDKKLASVLCVQ+LS
Sbjct  655   FDVNYKRKEPDSPIPKHVDQDAYRLLVVANKYLTGFDQPKLCAMYVDKKLASVLCVQALS  714

Query  704   RLNRSAPKWGKKTEDLFVLDFFNSVEDIQSAFDPFYTATSLSQATDINVLHELKDEMDDV  763
             RLNRSAPK GKKTEDLFVLDFFNSV+DI++AFDPFYT+T+LS+ATD+NVLHELKD+MDD 
Sbjct  715   RLNRSAPKYGKKTEDLFVLDFFNSVDDIKTAFDPFYTSTTLSEATDVNVLHELKDDMDDT  774

Query  764   GVYEWYEVEDFVTRYFKNEDAQTLSPIIDVAAARFDHELELEAEAKVDFKIKAKQFVKIY  823
             GVYEW+EVE+F  R+F   +AQ LSPIID+AAARF+HELELE E KVDFK+KAKQFVKIY
Sbjct  775   GVYEWFEVEEFNKRFFEGREAQDLSPIIDIAAARFNHELELENEFKVDFKVKAKQFVKIY  834

Query  824   GQMASIMPYEMVSWEKLFWFMKFLIPKLKVEDPDADAIDELLDSVDLSSYGLQRVKLNHS  883
             GQ+ASIMPYE+V WEKLFWF+KFLIPKL VEDPD +A+D LLDSVDLSSYGLQRVKLNHS
Sbjct  835   GQIASIMPYEVVQWEKLFWFLKFLIPKLSVEDPDKEALDSLLDSVDLSSYGLQRVKLNHS  894

Query  884   IKLSDQEAELDPQNPNPRGAHGGEKETDPLDEIIRTFNERWFQGWSATPEEQKVKFVNIA  943
             I L D E+ELDPQNPNPRGA G E E DPLDEII+ FNERWFQGWSATPEEQ+VKFVNIA
Sbjct  895   IELDDSETELDPQNPNPRGAYGPEAEKDPLDEIIKIFNERWFQGWSATPEEQRVKFVNIA  954

Query  944   ESIRNHPDFESKYKNNPDPHNRDLAFEKMLKEIMLQRRKDELELYKLFAGDSAFKASWTQ  1003
             ESIRNHPDFE+KY+NN+DPH R+LAFEKMLKEIMLQRRKDELELYKLFA D+AFKASWTQ
Sbjct  955   ESIRNHPDFEAKYQNNADPHTRELAFEKMLKEIMLQRRKDELELYKLFAQDPAFKASWTQ  1014

Query  1004  SMQRMVGM  1011
             SMQRMVGM
Sbjct  1015  SMQRMVGM  1022

12) HDN1F_11660 in NC_014366


> EU272902|14|G13|167832520|ACA01830.1|Vibrio_cholerae_Amazonia_3509|-|13968..17036|-|VPI2_0013c|type 
I restriction enzyme 
HsdR
Length=1022

 Score = 1263 bits (4793),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 768/1007 (77%), Positives = 892/1007 (89%), Gaps = 21/1007 (2%)

Query  27    KAAGGVADGSDAQVKETPADYLVGNQRFKLGLPTDFNAQYALDEKLFWRFLEHTQKPELT  86
             K+ +G+    +  + E+P +Y   N+ + +G P+DF+ QYALD +LFW+FLE+TQ +EL 
Sbjct  19    KGLAGICKE-ELALGEAPLNY--NNDLYLIGSPSDFDKQYALDTRLFWQFLEDTQASELE  75

Query  87    KLQKHNPSDWQRKLLERYDRLMkkhgilhllkkglPVDDAHFHLMYPAPLASSSEKVKQN  146
             KL++ +P DWQRK+LER+DR++ +HG+L+LLKKGL VDDA + LMYPAPLASSSEKVK++
Sbjct  76    KLKRTSPHDWQRKILERFDRMIMRHGVLRLLKKGLDVDDAFLSLMYPAPLASSSEKVKKD  135

Query  147   FAANIFSCTRQVRYSLANPLQEIDMVLFLNGIPLVTMELKNAWTGQTARYHGQKQYREDR  206
             F+AN+FS TRQV YS ANPL+EIDMVLF+NGIPL+T+ELKN+WTGQ A YHGQKQYR+DR
Sbjct  136   FSANLFSVTRQVCYSNANPLEEIDMVLFINGIPLITLELKNPWTGQNAVYHGQKQYRDDR  195

Query  207   DVNQPLLNFARCLVHMAVDTDEVYMTTKLAGQATYFLPFNKGHNHGKGNPPNPHGHKTAY  266
             D NQPLLNFARCLVHMAVDTDEVYMTTKLAG+ T+FLPFNKG N GKGNP NPHGHKTAY
Sbjct  196   DANQPLLNFARCLVHMAVDTDEVYMTTKLAGKNTFFLPFNKGFNFGKGNPINPHGHKTAY  255

Query  267   LWEEVFTKESIANIIQHFVRLDGSTKDPLPKRTLFFPRYHQLDVVRKLVDHASNQGVGHT  326
             LW+EVF KESIANIIQHF+RLDGS+K  L KRTLFFPRYHQ+DVVR+LVDH S +GVG+T
Sbjct  256   LWQEVFRKESIANIIQHFIRLDGSSKKQLDKRTLFFPRYHQMDVVRRLVDHCSVNGVGQT  315

Query  327   YLIQHSAGSGKSNSITWAAYQLIETYPASQQVANGRSIEQPLFDSVIVVTDRRLLDKQLR  386
             YLIQHSAGSGKSNSITWAAYQLIETYP S++++ +R+ E PLFDSVIVVTDRRLLDKQLR
Sbjct  316   YLIQHSAGSGKSNSITWAAYQLIETYPISDDLPGSRGKEVPLFDSVIVVTDRRLLDKQLR  375

Query  387   DNIKEFSEVKNIVAPAHKSSELKSALENGKKIIITTIQKFPFIVDGIEDLSDKRFAVIID  446
             DNIKEFSEVKNIVAPA KSSELKSALENGKKIIITTIQKFP+IVDGI DLSD+RFAVIID
Sbjct  376   DNIKEFSEVKNIVAPAFKSSELKSALENGKKIIITTIQKFPYIVDGIADLSDRRFAVIID  435

Query  447   EAHSSQSGTAHDNMNRVMGQDEEEDDQDKILKAMKSRKMRGNASYLAFTATPKNTTLEKF  506
             EAHSSQ G  +D++N  MG    ED  DK L++ K+RKMR+NASY+AFTATPKNTTLEKF
Sbjct  436   EAHSSQDGHNQDKLNEAMGF-VSEDVLDKALQSAKNRKMRSNASYFAFTATPKNTTLEKF  494

Query  507   GEKQEDGTFTPFHLYSMKQAIEEGFILDVLANYTTYKSYYEIEKSIAENPEFDTKKAQKK  566
             G++Q DGT+ PFHLYSMKQAIEEGFILDV+ANYTTYKSYYEIEKSI +NPEFD+KKAQK+
Sbjct  495   GQRQADGTYVPFHLYSMKQAIEEGFILDVIANYTTYKSYYEIEKSIQDNPEFDSKKAQKR  554

Query  567   LRTYVERSQQTIDTKAEIMLEHFIPQVVNAKKLKGKAKGMVVTQNIETAIRYHKAITRLL  626
             LR+YVE SQ+TIDTKAEIMLEHFI +VVN+KKLKGK+KGMVVTQNIE+AIRY +A+T  L
Sbjct  555   LRAYVEASQETIDTKAEIMLEHFIKHVVNGKKLKGKGKGMVVTQNIESAIRYYRALTIQL  614

Query  627   EAKGNPFKALVAFSGTKEVDGIEYTEAEINGFSESDTKDKFDT-----------------  669
             +  GNPFK  +AFSG+KEVDGIEYTEA+INGF+E+DTKD FD                  
Sbjct  615   NKMGNPFKVAIAFSGSKEVDGIEYTEADINGFPEGDTKDYFDVNYKRKEPDSPIPKHVDQ  674

Query  670   DEYRLLVVANKYLTGFDQPKLCAMYVDKKLASVLCVQTLSRLNRSAPKLGKKTEDLFILD  729
             D YRLLVVANKYLTGFDQPKLCAMYVDKKLASVLCVQ+LSRLNRSAPK GKKTEDLF+LD
Sbjct  675   DAYRLLVVANKYLTGFDQPKLCAMYVDKKLASVLCVQALSRLNRSAPKYGKKTEDLFVLD  734

Query  730   FFNSVDDVKTAFDPFYTATSLSRATDINVLHELKDAMDDVGVYEWYEVEDFVKRYFNNED  789
             FFNSVDD+KTAFDPFYT+T+LS ATD+NVLHELKD MDD GVYEW+EVE+F KR+F+  +
Sbjct  735   FFNSVDDIKTAFDPFYTSTTLSEATDVNVLHELKDDMDDTGVYEWFEVEEFNKRFFEGRE  794

Query  790   AQTLSPIIDVAAARFEHELELEDDEKVDFKIKAKQYVKIYGQMASIMPYEIVAWEKLFWF  849
             AQ LSPIID+AAARF+HELELE++ KVDFK+KAKQ+VKIYGQ+ASIMPYE+V WEKLFWF
Sbjct  795   AQDLSPIIDIAAARFNHELELENEFKVDFKVKAKQFVKIYGQIASIMPYEVVQWEKLFWF  854

Query  850   LKFLIPKLKVADPDADTIDELLESVDLSSYGLQRVKLNHTIKLDEADTELDPQNPNPRGA  909
             LKFLIPKL V DPD +++D LL+SVDLSSYGLQRVKLNH+I LD+++TELDPQNPNPRGA
Sbjct  855   LKFLIPKLSVEDPDKEALDSLLDSVDLSSYGLQRVKLNHSIELDDSETELDPQNPNPRGA  914

Query  910   HGVDKQTDPLDDIIRTFNERWFQGWSATPEEQKVKFINIAESIKQHPDFEAKYQNNPDPH  969
              G + + DPLD+II+ FNERWFQGWSATPEEQ+VKF+NIAESI++HPDFEAKYQNN+DPH
Sbjct  915   YGPEAEKDPLDEIIKIFNERWFQGWSATPEEQRVKFVNIAESIRNHPDFEAKYQNNADPH  974

Query  970   NRELAFEKMLKEVMLRRRKDELELYKLFAGDAAFKAAWMQSMQRMIG  1016
              RELAFEKMLKE+ML+RRKDELELYKLFA D+AFKA+W QSMQRM+G
Sbjct  975   TRELAFEKMLKEIMLQRRKDELELYKLFAQDPAFKASWTQSMQRMVG  1021

13) HP15_1582 in NC_017506


> EU272902|14|G13|167832520|ACA01830.1|Vibrio_cholerae_Amazonia_3509|-|13968..17036|-|VPI2_0013c|type 
I restriction enzyme 
HsdR
Length=1022

 Score = 1259 bits (4777),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 763/1025 (75%), Positives = 902/1025 (88%), Gaps = 24/1025 (2%)

Query  1     MVSQTNEQALEAAIERALTGLTTEAVKQAGKVKETPADDLVANNGFQLGLPYDFNAQYAI  60
             MVS+TNEQALEAAIE++L+G+  E +     + E+P +    N+ + +G P DF+ QYA+
Sbjct  4     MVSKTNEQALEAAIEKGLAGICKEELA----LGEAPLN--YNNDLYLIGSPSDFDKQYAL  57

Query  61    DEKLFWRFLEQTQGKELAKLKKHNSTDWDRKLLERYDRlikkhgilhllkkglAVDDAHF  120
             D +LFW+FLE+TQ+ EL KLK+ ++ DW+RK+LER+DR+I +HG+L+LLKKGL VDDA +
Sbjct  58    DTRLFWQFLEDTQASELEKLKRTSPHDWQRKILERFDRMIMRHGVLRLLKKGLDVDDAFL  117

Query  121   HLMYPAPLASSSEKVKQNYAANIFSCTRQVRYSLANPLQEIDMVLFLNGIPLVTMELKNA  180
              LMYPAPLASSSEKVK++++AN+FS TRQV YS ANPL+EIDMVLF+NGIPL+T+ELKN+
Sbjct  118   SLMYPAPLASSSEKVKKDFSANLFSVTRQVCYSNANPLEEIDMVLFINGIPLITLELKNP  177

Query  181   WTGQTARYHGQKQYRENRDTNQPLLNFARCLVHMAVDTDEVYMTTKLNGKSTFFLPFNKG  240
             WTGQ A YHGQKQYR++RD+NQPLLNFARCLVHMAVDTDEVYMTTKL GK+TFFLPFNKG
Sbjct  178   WTGQNAVYHGQKQYRDDRDANQPLLNFARCLVHMAVDTDEVYMTTKLAGKNTFFLPFNKG  237

Query  241   HNHGKGNPPNPHGHKSSYLWEEVFTKDSLVNIIQHFVRLDGSSKDPLRKRTLFFPRYHQM  300
              N GKGNP NPHGHK++YLW+EVF K+S+ NIIQHF+RLDGSSK  L KRTLFFPRYHQM
Sbjct  238   FNFGKGNPINPHGHKTAYLWQEVFRKESIANIIQHFIRLDGSSKKQLDKRTLFFPRYHQM  297

Query  301   DVVRKLVAHAEDHGVGHTYLIQHSAGSGKSNSITWAAYQLIETYPKNDAAAGGKDQDQPL  360
             DVVR+LV H   +GVG+TYLIQHSAGSGKSNSITWAAYQLIETYP +D  +G+++++ PL
Sbjct  298   DVVRRLVDHCSVNGVGQTYLIQHSAGSGKSNSITWAAYQLIETYPISDDLPGSRGKEVPL  357

Query  361   FDSVIVVTDRRLLDKQIRENIKEFSEVKNIVAPAFKSSELKSALESGKKIIITTIQKFPF  420
             FDSVIVVTDRRLLDKQ+R+NIKEFSEVKNIVAPAFKSSELKSALE+GKKIIITTIQKFP+
Sbjct  358   FDSVIVVTDRRLLDKQLRDNIKEFSEVKNIVAPAFKSSELKSALENGKKIIITTIQKFPY  417

Query  421   IVEGIEDLGDKRFAVIIDEAHSSQSGSAHDNMNRAMGQEDDEDEQDKILKAMRSRKMRGN  480
             IV+GI DL+D+RFAVIIDEAHSSQ G  +D++N AMG    ED  DK L++ ++RKMR+N
Sbjct  418   IVDGIADLSDRRFAVIIDEAHSSQDGHNQDKLNEAMGFV-SEDVLDKALQSAKNRKMRSN  476

Query  481   ASYMAFTATPKNTTFEKFGEKQDDGTFREFHLYSMKQAIEEGFILDVLANYTTYKSYYEI  540
             ASY AFTATPKNTT+EKFG++Q DGT+  FHLYSMKQAIEEGFILDV+ANYTTYKSYYEI
Sbjct  477   ASYFAFTATPKNTTLEKFGQRQADGTYVPFHLYSMKQAIEEGFILDVIANYTTYKSYYEI  536

Query  541   EKSIAENPQFDTKKAQKKLRAYVESSQQTINTKAEIMLEHFIPQVVNTKKLKGKAKGMVV  600
             EKSI +NP+FD+KKAQK+LRAYVE+SQ+TI+TKAEIMLEHFI +VVN KKLKGK+KGMVV
Sbjct  537   EKSIQDNPEFDSKKAQKRLRAYVEASQETIDTKAEIMLEHFIKHVVNGKKLKGKGKGMVV  596

Query  601   TQNIETAIRYHRAISRILEKNGNPFKALVAFSGTKEVDGIEYTEADINGFSENDTKDKFD  660
             TQNIE+AIRY RA++  L+K GNPFK  +AFSG+KEVDGIEYTEADINGF+E DTKD FD
Sbjct  597   TQNIESAIRYYRALTIQLNKMGNPFKVAIAFSGSKEVDGIEYTEADINGFPEGDTKDYFD  656

Query  661   T-----------------DEYRLLVVANKYLTGFDQPKLCAMYVDKKLASVMCVQTLSRL  703
                               D YRLLVVANKYLTGFDQPKLCAMYVDKKLASV+CVQ+LSRL
Sbjct  657   VNYKRKEPDSPIPKHVDQDAYRLLVVANKYLTGFDQPKLCAMYVDKKLASVLCVQALSRL  716

Query  704   NRAAPKLGKKTEDLFILDFFNTTDDIKTAFDPFYTATSLSGATDVNVLHELKDAMDEVGV  763
             NR+APK GKKTEDLF+LDFFN+ DDIKTAFDPFYT+T+LS ATDVNVLHELKD MD+ GV
Sbjct  717   NRSAPKYGKKTEDLFVLDFFNSVDDIKTAFDPFYTSTTLSEATDVNVLHELKDDMDDTGV  776

Query  764   YEWHEVEDFVARYFDGEDAQNLSPIIDVAASRFEHELELEDDDKVDFKIKAKQYVKIYGQ  823
             YEW EVE+F  R+F+G +AQ+LSPIID+AA+RF+HELELE++ KVDFK+KAKQ+VKIYGQ
Sbjct  777   YEWFEVEEFNKRFFEGREAQDLSPIIDIAAARFNHELELENEFKVDFKVKAKQFVKIYGQ  836

Query  824   MAAIMPYEIVAWEKLFWFLKFLIPKLKVKDPDTDAIDELLESVDLSSYGLQRVKLNHSIS  883
             +A+IMPYE+V WEKLFWFLKFLIPKL V DPD +A+D LL+SVDLSSYGLQRVKLNHSI 
Sbjct  837   IASIMPYEVVQWEKLFWFLKFLIPKLSVEDPDKEALDSLLDSVDLSSYGLQRVKLNHSIE  896

Query  884   LDEEESGVDPQNPNPRGALGDGPQEDPLDEIVRTFNERWFQGWTATPEEQKVKFVNIAES  943
             LD+ E+ +DPQNPNPRGA G  ++ DPLDEI++ FNERWFQGW+ATPEEQ+VKFVNIAES
Sbjct  897   LDDSETELDPQNPNPRGAYGPEAEKDPLDEIIKIFNERWFQGWSATPEEQRVKFVNIAES  956

Query  944   IRQHPDFEAKYQNNPDPHNRELAFEKMLKEVMLRRRKDELELYKMFAGDAAFKTAWMQSM  1003
             IR+HPDFEAKYQNN+DPH RELAFEKMLKE+ML+RRKDELELYK+FA D+AFK++W QSM
Sbjct  957   IRNHPDFEAKYQNNADPHTRELAFEKMLKEIMLQRRKDELELYKLFAQDPAFKASWTQSM  1016

Query  1004  QRMVD  1008
             QRMV+
Sbjct  1017  QRMVG  1021

14) amad1_05840 in NC_019393


> EU272902|14|G13|167832520|ACA01830.1|Vibrio_cholerae_Amazonia_3509|-|13968..17036|-|VPI2_0013c|type 
I restriction enzyme 
HsdR
Length=1022

 Score = 1251 bits (4747),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 775/983 (79%), Positives = 874/983 (89%), Gaps = 21/983 (2%)

Query  1     MVSQTNEQALESAIDERFFWQFLQKTQEEELAKLQKNNSSDWQRKLLERFDRlikkhgil  60
             +++  ++   + A+D R+FWQFL+ TQ  EL KL++ ++ DWQRK+LERFDR+I +HG+L
Sbjct  44    LIGSPSDFDKQYALDTRLFWQFLEDTQASELEKLKRTSPHDWQRKILERFDRMIMRHGVL  103

Query  61    hllkkglSVDDAHFNLLYPAPLASSSEKVKQNFADNVFSCTRQVRYSMANPLQEIDMVLF  120
             +LLKKGL VDDA ++L+YPAPLASSSEKVK++F+ N+FS TRQV YS ANPL+EIDMVLF
Sbjct  104   RLLKKGLDVDDAFLSLMYPAPLASSSEKVKKDFSANLFSVTRQVCYSNANPLEEIDMVLF  163

Query  121   INGIPLITLELKNAWTGQTARYHGQKQYRDDRDAAQALLTFGRCLVHMAVDTDEVYMTTK  180
             INGIPLITLELKN+WTGQ A YHGQKQYRDDRDA Q+LL F+RCLVHMAVDTDEVYMTTK
Sbjct  164   INGIPLITLELKNPWTGQNAVYHGQKQYRDDRDANQPLLNFARCLVHMAVDTDEVYMTTK  223

Query  181   LSGGSTFFLPFNKGHNLGQGNPPNPTGHKTAYLWQEVFTKESLANIIQHFVRLDGSSKDP  240
             L+G +TFFLPFNKG N+G+GNP NP GHKTAYLWQEVF KES+ANIIQHF+RLDGSSK  
Sbjct  224   LAGKNTFFLPFNKGFNFGKGNPINPHGHKTAYLWQEVFRKESIANIIQHFIRLDGSSKKQ  283

Query  241   LPKRTLFFPRYHQLDVVRKLVDHAAQYGVGQTYLIQHSAGSGKSNSITWAAYQLIETYPA  300
             L KRTLFFPRYHQ+DVVR+LVDH +  GVGQTYLIQHSAGSGKSNSITWAAYQLIETYP 
Sbjct  284   LDKRTLFFPRYHQMDVVRRLVDHCSVNGVGQTYLIQHSAGSGKSNSITWAAYQLIETYPI  343

Query  301   SSDVAGGKSLEQPLFDSVIVVTDRRLLDKQLRDNIKEFSEVKNIIAPANKSSELKQALEN  360
             S D++G+++ E PLFDSVIVVTDRRLLDKQLRDNIKEFSEVKNI+APA KSSELK ALEN
Sbjct  344   SDDLPGSRGKEVPLFDSVIVVTDRRLLDKQLRDNIKEFSEVKNIVAPAFKSSELKSALEN  403

Query  361   GKKIIITTIQKFPFIIDGIADLSDKRFAVIIDEAHSSQSGSAHDNMNRAMGKSEIEEAED  420
             GKKIIITTIQKFP+I+DGIADLSD+RFAVIIDEAHSSQ G  +D++N AMG      +ED
Sbjct  404   GKKIIITTIQKFPYIVDGIADLSDRRFAVIIDEAHSSQDGHNQDKLNEAMGFV----SED  459

Query  421   AQDKILQAMKSRKMRGNASYLAFTATPKNSTLEKFGQRQEDGSFKPFHLYSMKQAIEEGF  480
               DK LQ+ K+RKMR+NASY+AFTATPKN+TLEKFGQRQ DG++ PFHLYSMKQAIEEGF
Sbjct  460   VLDKALQSAKNRKMRSNASYFAFTATPKNTTLEKFGQRQADGTYVPFHLYSMKQAIEEGF  519

Query  481   ILDVLANYTTYKSYYEIEKSIADNPEFDTKKAQKKLRAYVERSQQTIDTKAEIMLEHFVP  540
             ILDV+ANYTTYKSYYEIEKSI DNPEFD+KKAQK+LRAYVE SQ+TIDTKAEIMLEHF+ 
Sbjct  520   ILDVIANYTTYKSYYEIEKSIQDNPEFDSKKAQKRLRAYVEASQETIDTKAEIMLEHFIK  579

Query  541   HVVNAkklkgkgkgMVVTQNIETAIRYYKAIRRILEEQGNPFKVAIAFSGTKEVDGIEYT  600
             HVVN+KKLKGKGKGMVVTQNIE+AIRYY+A+   L+  GNPFKVAIAFSG+KEVDGIEYT
Sbjct  580   HVVNGKKLKGKGKGMVVTQNIESAIRYYRALTIQLNKMGNPFKVAIAFSGSKEVDGIEYT  639

Query  601   EADINGFAESDTKDMFDT-----------------DEYRLLVVANKYLTGFDQPKLCAMY  643
             EADINGF+E+DTKD FD                  D YRLLVVANKYLTGFDQPKLCAMY
Sbjct  640   EADINGFPEGDTKDYFDVNYKRKEPDSPIPKHVDQDAYRLLVVANKYLTGFDQPKLCAMY  699

Query  644   VDKKLASVLCVQTLSRLNRSAPKWGKKTEDLFVLDFFNSVEDIQSAFDPFYTATSLSQAT  703
             VDKKLASVLCVQ+LSRLNRSAPK GKKTEDLFVLDFFNSV+DI++AFDPFYT+T+LS+AT
Sbjct  700   VDKKLASVLCVQALSRLNRSAPKYGKKTEDLFVLDFFNSVDDIKTAFDPFYTSTTLSEAT  759

Query  704   DINVLHELKDEMDDVGVYEWYEVEDFVTRYFKNEDAQTLSPIIDVAAARFDHELELEAEA  763
             D+NVLHELKD+MDD GVYEW+EVE+F  R+F   +AQ LSPIID+AAARF+HELELE E 
Sbjct  760   DVNVLHELKDDMDDTGVYEWFEVEEFNKRFFEGREAQDLSPIIDIAAARFNHELELENEF  819

Query  764   KVDFKIKAKQFVKIYGQMASIMPYEMVSWEKLFWFLKFLIPKLKVEDPDADAIDELLDSV  823
             KVDFK+KAKQFVKIYGQ+ASIMPYE+V WEKLFWFLKFLIPKL VEDPD +A+D LLDSV
Sbjct  820   KVDFKVKAKQFVKIYGQIASIMPYEVVQWEKLFWFLKFLIPKLSVEDPDKEALDSLLDSV  879

Query  824   DLSSYGLQRVKLNHSIKLSDQEAELDPQNPNPRGAHGGEKETDPLDEIIRTFNERWFQGW  883
             DLSSYGLQRVKLNHSI L D E+ELDPQNPNPRGA G E E DPLDEII+ FNERWFQGW
Sbjct  880   DLSSYGLQRVKLNHSIELDDSETELDPQNPNPRGAYGPEAEKDPLDEIIKIFNERWFQGW  939

Query  884   SATPEEQKVKFVNIAESIRNHPDFESKYKNNPDPHNRDLAFEKMLKEIMLQRRKDELELY  943
             SATPEEQ+VKFVNIAESIRNHPDFE+KY+NN+DPH R+LAFEKMLKEIMLQRRKDELELY
Sbjct  940   SATPEEQRVKFVNIAESIRNHPDFEAKYQNNADPHTRELAFEKMLKEIMLQRRKDELELY  999

Query  944   KLFAGDSAFKASWTQSMQRMVGM  966
             KLFA D+AFKASWTQSMQRMVGM
Sbjct  1000  KLFAQDPAFKASWTQSMQRMVGM  1022

15) I636_05855 in NC_021714


> EU272902|14|G13|167832520|ACA01830.1|Vibrio_cholerae_Amazonia_3509|-|13968..17036|-|VPI2_0013c|type 
I restriction enzyme 
HsdR
Length=1022

 Score = 1251 bits (4747),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 775/983 (79%), Positives = 874/983 (89%), Gaps = 21/983 (2%)

Query  1     MVSQTNEQALESAIDERFFWQFLQKTQEEELAKLQKNNSSDWQRKLLERFDRlikkhgil  60
             +++  ++   + A+D R+FWQFL+ TQ  EL KL++ ++ DWQRK+LERFDR+I +HG+L
Sbjct  44    LIGSPSDFDKQYALDTRLFWQFLEDTQASELEKLKRTSPHDWQRKILERFDRMIMRHGVL  103

Query  61    hllkkglSVDDAHFNLLYPAPLASSSEKVKQNFADNVFSCTRQVRYSMANPLQEIDMVLF  120
             +LLKKGL VDDA ++L+YPAPLASSSEKVK++F+ N+FS TRQV YS ANPL+EIDMVLF
Sbjct  104   RLLKKGLDVDDAFLSLMYPAPLASSSEKVKKDFSANLFSVTRQVCYSNANPLEEIDMVLF  163

Query  121   INGIPLITLELKNAWTGQTARYHGQKQYRDDRDAAQALLTFGRCLVHMAVDTDEVYMTTK  180
             INGIPLITLELKN+WTGQ A YHGQKQYRDDRDA Q+LL F+RCLVHMAVDTDEVYMTTK
Sbjct  164   INGIPLITLELKNPWTGQNAVYHGQKQYRDDRDANQPLLNFARCLVHMAVDTDEVYMTTK  223

Query  181   LSGGSTFFLPFNKGHNLGQGNPPNPTGHKTAYLWQEVFTKESLANIIQHFVRLDGSSKDP  240
             L+G +TFFLPFNKG N+G+GNP NP GHKTAYLWQEVF KES+ANIIQHF+RLDGSSK  
Sbjct  224   LAGKNTFFLPFNKGFNFGKGNPINPHGHKTAYLWQEVFRKESIANIIQHFIRLDGSSKKQ  283

Query  241   LPKRTLFFPRYHQLDVVRKLVDHAAQYGVGQTYLIQHSAGSGKSNSITWAAYQLIETYPA  300
             L KRTLFFPRYHQ+DVVR+LVDH +  GVGQTYLIQHSAGSGKSNSITWAAYQLIETYP 
Sbjct  284   LDKRTLFFPRYHQMDVVRRLVDHCSVNGVGQTYLIQHSAGSGKSNSITWAAYQLIETYPI  343

Query  301   SSDVAGGKSLEQPLFDSVIVVTDRRLLDKQLRDNIKEFSEVKNIIAPANKSSELKQALEN  360
             S D++G+++ E PLFDSVIVVTDRRLLDKQLRDNIKEFSEVKNI+APA KSSELK ALEN
Sbjct  344   SDDLPGSRGKEVPLFDSVIVVTDRRLLDKQLRDNIKEFSEVKNIVAPAFKSSELKSALEN  403

Query  361   GKKIIITTIQKFPFIIDGIADLSDKRFAVIIDEAHSSQSGSAHDNMNRAMGKSEIEEAED  420
             GKKIIITTIQKFP+I+DGIADLSD+RFAVIIDEAHSSQ G  +D++N AMG      +ED
Sbjct  404   GKKIIITTIQKFPYIVDGIADLSDRRFAVIIDEAHSSQDGHNQDKLNEAMGFV----SED  459

Query  421   AQDKILQAMKSRKMRGNASYLAFTATPKNSTLEKFGQRQEDGSFKPFHLYSMKQAIEEGF  480
               DK LQ+ K+RKMR+NASY+AFTATPKN+TLEKFGQRQ DG++ PFHLYSMKQAIEEGF
Sbjct  460   VLDKALQSAKNRKMRSNASYFAFTATPKNTTLEKFGQRQADGTYVPFHLYSMKQAIEEGF  519

Query  481   ILDVLANYTTYKSYYEIEKSIADNPEFDTKKAQKKLRAYVERSQQTIDTKAEIMLEHFVP  540
             ILDV+ANYTTYKSYYEIEKSI DNPEFD+KKAQK+LRAYVE SQ+TIDTKAEIMLEHF+ 
Sbjct  520   ILDVIANYTTYKSYYEIEKSIQDNPEFDSKKAQKRLRAYVEASQETIDTKAEIMLEHFIK  579

Query  541   HVVNAkklkgkgkgMVVTQNIETAIRYYKAIRRILEEQGNPFKVAIAFSGTKEVDGIEYT  600
             HVVN+KKLKGKGKGMVVTQNIE+AIRYY+A+   L+  GNPFKVAIAFSG+KEVDGIEYT
Sbjct  580   HVVNGKKLKGKGKGMVVTQNIESAIRYYRALTIQLNKMGNPFKVAIAFSGSKEVDGIEYT  639

Query  601   EADINGFAESDTKDMFDT-----------------DEYRLLVVANKYLTGFDQPKLCAMY  643
             EADINGF+E+DTKD FD                  D YRLLVVANKYLTGFDQPKLCAMY
Sbjct  640   EADINGFPEGDTKDYFDVNYKRKEPDSPIPKHVDQDAYRLLVVANKYLTGFDQPKLCAMY  699

Query  644   VDKKLASVLCVQTLSRLNRSAPKWGKKTEDLFVLDFFNSVEDIQSAFDPFYTATSLSQAT  703
             VDKKLASVLCVQ+LSRLNRSAPK GKKTEDLFVLDFFNSV+DI++AFDPFYT+T+LS+AT
Sbjct  700   VDKKLASVLCVQALSRLNRSAPKYGKKTEDLFVLDFFNSVDDIKTAFDPFYTSTTLSEAT  759

Query  704   DINVLHELKDEMDDVGVYEWYEVEDFVTRYFKNEDAQTLSPIIDVAAARFDHELELEAEA  763
             D+NVLHELKD+MDD GVYEW+EVE+F  R+F   +AQ LSPIID+AAARF+HELELE E 
Sbjct  760   DVNVLHELKDDMDDTGVYEWFEVEEFNKRFFEGREAQDLSPIIDIAAARFNHELELENEF  819

Query  764   KVDFKIKAKQFVKIYGQMASIMPYEMVSWEKLFWFLKFLIPKLKVEDPDADAIDELLDSV  823
             KVDFK+KAKQFVKIYGQ+ASIMPYE+V WEKLFWFLKFLIPKL VEDPD +A+D LLDSV
Sbjct  820   KVDFKVKAKQFVKIYGQIASIMPYEVVQWEKLFWFLKFLIPKLSVEDPDKEALDSLLDSV  879

Query  824   DLSSYGLQRVKLNHSIKLSDQEAELDPQNPNPRGAHGGEKETDPLDEIIRTFNERWFQGW  883
             DLSSYGLQRVKLNHSI L D E+ELDPQNPNPRGA G E E DPLDEII+ FNERWFQGW
Sbjct  880   DLSSYGLQRVKLNHSIELDDSETELDPQNPNPRGAYGPEAEKDPLDEIIKIFNERWFQGW  939

Query  884   SATPEEQKVKFVNIAESIRNHPDFESKYKNNPDPHNRDLAFEKMLKEIMLQRRKDELELY  943
             SATPEEQ+VKFVNIAESIRNHPDFE+KY+NN+DPH R+LAFEKMLKEIMLQRRKDELELY
Sbjct  940   SATPEEQRVKFVNIAESIRNHPDFEAKYQNNADPHTRELAFEKMLKEIMLQRRKDELELY  999

Query  944   KLFAGDSAFKASWTQSMQRMVGM  966
             KLFA D+AFKASWTQSMQRMVGM
Sbjct  1000  KLFAQDPAFKASWTQSMQRMVGM  1022

16) I635_05820 in NC_021713


> EU272902|14|G13|167832520|ACA01830.1|Vibrio_cholerae_Amazonia_3509|-|13968..17036|-|VPI2_0013c|type 
I restriction enzyme 
HsdR
Length=1022

 Score = 1251 bits (4747),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 775/983 (79%), Positives = 874/983 (89%), Gaps = 21/983 (2%)

Query  1     MVSQTNEQALESAIDERFFWQFLQKTQEEELAKLQKNNSSDWQRKLLERFDRlikkhgil  60
             +++  ++   + A+D R+FWQFL+ TQ  EL KL++ ++ DWQRK+LERFDR+I +HG+L
Sbjct  44    LIGSPSDFDKQYALDTRLFWQFLEDTQASELEKLKRTSPHDWQRKILERFDRMIMRHGVL  103

Query  61    hllkkglSVDDAHFNLLYPAPLASSSEKVKQNFADNVFSCTRQVRYSMANPLQEIDMVLF  120
             +LLKKGL VDDA ++L+YPAPLASSSEKVK++F+ N+FS TRQV YS ANPL+EIDMVLF
Sbjct  104   RLLKKGLDVDDAFLSLMYPAPLASSSEKVKKDFSANLFSVTRQVCYSNANPLEEIDMVLF  163

Query  121   INGIPLITLELKNAWTGQTARYHGQKQYRDDRDAAQALLTFGRCLVHMAVDTDEVYMTTK  180
             INGIPLITLELKN+WTGQ A YHGQKQYRDDRDA Q+LL F+RCLVHMAVDTDEVYMTTK
Sbjct  164   INGIPLITLELKNPWTGQNAVYHGQKQYRDDRDANQPLLNFARCLVHMAVDTDEVYMTTK  223

Query  181   LSGGSTFFLPFNKGHNLGQGNPPNPTGHKTAYLWQEVFTKESLANIIQHFVRLDGSSKDP  240
             L+G +TFFLPFNKG N+G+GNP NP GHKTAYLWQEVF KES+ANIIQHF+RLDGSSK  
Sbjct  224   LAGKNTFFLPFNKGFNFGKGNPINPHGHKTAYLWQEVFRKESIANIIQHFIRLDGSSKKQ  283

Query  241   LPKRTLFFPRYHQLDVVRKLVDHAAQYGVGQTYLIQHSAGSGKSNSITWAAYQLIETYPA  300
             L KRTLFFPRYHQ+DVVR+LVDH +  GVGQTYLIQHSAGSGKSNSITWAAYQLIETYP 
Sbjct  284   LDKRTLFFPRYHQMDVVRRLVDHCSVNGVGQTYLIQHSAGSGKSNSITWAAYQLIETYPI  343

Query  301   SSDVAGGKSLEQPLFDSVIVVTDRRLLDKQLRDNIKEFSEVKNIIAPANKSSELKQALEN  360
             S D++G+++ E PLFDSVIVVTDRRLLDKQLRDNIKEFSEVKNI+APA KSSELK ALEN
Sbjct  344   SDDLPGSRGKEVPLFDSVIVVTDRRLLDKQLRDNIKEFSEVKNIVAPAFKSSELKSALEN  403

Query  361   GKKIIITTIQKFPFIIDGIADLSDKRFAVIIDEAHSSQSGSAHDNMNRAMGKSEIEEAED  420
             GKKIIITTIQKFP+I+DGIADLSD+RFAVIIDEAHSSQ G  +D++N AMG      +ED
Sbjct  404   GKKIIITTIQKFPYIVDGIADLSDRRFAVIIDEAHSSQDGHNQDKLNEAMGFV----SED  459

Query  421   AQDKILQAMKSRKMRGNASYLAFTATPKNSTLEKFGQRQEDGSFKPFHLYSMKQAIEEGF  480
               DK LQ+ K+RKMR+NASY+AFTATPKN+TLEKFGQRQ DG++ PFHLYSMKQAIEEGF
Sbjct  460   VLDKALQSAKNRKMRSNASYFAFTATPKNTTLEKFGQRQADGTYVPFHLYSMKQAIEEGF  519

Query  481   ILDVLANYTTYKSYYEIEKSIADNPEFDTKKAQKKLRAYVERSQQTIDTKAEIMLEHFVP  540
             ILDV+ANYTTYKSYYEIEKSI DNPEFD+KKAQK+LRAYVE SQ+TIDTKAEIMLEHF+ 
Sbjct  520   ILDVIANYTTYKSYYEIEKSIQDNPEFDSKKAQKRLRAYVEASQETIDTKAEIMLEHFIK  579

Query  541   HVVNAkklkgkgkgMVVTQNIETAIRYYKAIRRILEEQGNPFKVAIAFSGTKEVDGIEYT  600
             HVVN+KKLKGKGKGMVVTQNIE+AIRYY+A+   L+  GNPFKVAIAFSG+KEVDGIEYT
Sbjct  580   HVVNGKKLKGKGKGMVVTQNIESAIRYYRALTIQLNKMGNPFKVAIAFSGSKEVDGIEYT  639

Query  601   EADINGFAESDTKDMFDT-----------------DEYRLLVVANKYLTGFDQPKLCAMY  643
             EADINGF+E+DTKD FD                  D YRLLVVANKYLTGFDQPKLCAMY
Sbjct  640   EADINGFPEGDTKDYFDVNYKRKEPDSPIPKHVDQDAYRLLVVANKYLTGFDQPKLCAMY  699

Query  644   VDKKLASVLCVQTLSRLNRSAPKWGKKTEDLFVLDFFNSVEDIQSAFDPFYTATSLSQAT  703
             VDKKLASVLCVQ+LSRLNRSAPK GKKTEDLFVLDFFNSV+DI++AFDPFYT+T+LS+AT
Sbjct  700   VDKKLASVLCVQALSRLNRSAPKYGKKTEDLFVLDFFNSVDDIKTAFDPFYTSTTLSEAT  759

Query  704   DINVLHELKDEMDDVGVYEWYEVEDFVTRYFKNEDAQTLSPIIDVAAARFDHELELEAEA  763
             D+NVLHELKD+MDD GVYEW+EVE+F  R+F   +AQ LSPIID+AAARF+HELELE E 
Sbjct  760   DVNVLHELKDDMDDTGVYEWFEVEEFNKRFFEGREAQDLSPIIDIAAARFNHELELENEF  819

Query  764   KVDFKIKAKQFVKIYGQMASIMPYEMVSWEKLFWFLKFLIPKLKVEDPDADAIDELLDSV  823
             KVDFK+KAKQFVKIYGQ+ASIMPYE+V WEKLFWFLKFLIPKL VEDPD +A+D LLDSV
Sbjct  820   KVDFKVKAKQFVKIYGQIASIMPYEVVQWEKLFWFLKFLIPKLSVEDPDKEALDSLLDSV  879

Query  824   DLSSYGLQRVKLNHSIKLSDQEAELDPQNPNPRGAHGGEKETDPLDEIIRTFNERWFQGW  883
             DLSSYGLQRVKLNHSI L D E+ELDPQNPNPRGA G E E DPLDEII+ FNERWFQGW
Sbjct  880   DLSSYGLQRVKLNHSIELDDSETELDPQNPNPRGAYGPEAEKDPLDEIIKIFNERWFQGW  939

Query  884   SATPEEQKVKFVNIAESIRNHPDFESKYKNNPDPHNRDLAFEKMLKEIMLQRRKDELELY  943
             SATPEEQ+VKFVNIAESIRNHPDFE+KY+NN+DPH R+LAFEKMLKEIMLQRRKDELELY
Sbjct  940   SATPEEQRVKFVNIAESIRNHPDFEAKYQNNADPHTRELAFEKMLKEIMLQRRKDELELY  999

Query  944   KLFAGDSAFKASWTQSMQRMVGM  966
             KLFA D+AFKASWTQSMQRMVGM
Sbjct  1000  KLFAQDPAFKASWTQSMQRMVGM  1022

17) CYCME_2461 in NC_021917


> EU272902|14|G13|167832520|ACA01830.1|Vibrio_cholerae_Amazonia_3509|-|13968..17036|-|VPI2_0013c|type 
I restriction enzyme 
HsdR
Length=1022

 Score = 1247 bits (4730),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 800/1025 (79%), Positives = 903/1025 (89%), Gaps = 23/1025 (2%)

Query  1     MVSQTNEQALEAAIETALVGSCLEERKNQVKEVIPDYGNKYYQPGSPIDFNKQYALDERF  60
             MVS+TNEQALEAAIE +L G C EE    + E   +Y N  Y  GSP DF+KQYALD R+
Sbjct  4     MVSKTNEQALEAAIEKGLAGICKEE--LALGEAPLNYNNDLYLIGSPSDFDKQYALDTRL  61

Query  61    FWAFLEKTQEDELEKIKRNNPNDWQRKIYERFDRlikkhgilhllkkglSVDDAHFNLMY  120
             FW FLE TQ  ELEK+KR +P+DWQRKI ERFDR+I +HG+L+LLKKGL VDDA ++LMY
Sbjct  62    FWQFLEDTQASELEKLKRTSPHDWQRKILERFDRMIMRHGVLRLLKKGLDVDDAFLSLMY  121

Query  121   PAPLASSSEKVKQNFSENLFSCTRQLRYSQANPLQEIDMVLFINGIPLITLELKNAWTNQ  180
             PAPLASSSEKVK++FS NLFS TRQ+ YS+ANPL+EIDMVLFINGIPLITLELKN+WT Q
Sbjct  122   PAPLASSSEKVKKDFSANLFSVTRQVCYSNANPLEEIDMVLFINGIPLITLELKNPWTGQ  181

Query  181   TARYHGQKQYREDRDTNQPLLNFGRCLVHMAVDTDEVYMTTKLAGKATFFLPFNKGHNLG  240
              A YHGQKQYR+DRD+NQPLLNF+RCLVHMAVDTDEVYMTTKLAGK TFFLPFNKG N+G
Sbjct  182   NAVYHGQKQYRDDRDANQPLLNFARCLVHMAVDTDEVYMTTKLAGKNTFFLPFNKGFNFG  241

Query  241   QGNPPNQTGHKTAYLWEEVFTKESLANIIQHFVRLDGSSKDPLNKRTLFFPRYHQMDVVR  300
             +GNP N  GHKTAYLW+EVF KES+ANIIQHF+RLDGSSK  L+KRTLFFPRYHQMDVVR
Sbjct  242   KGNPINPHGHKTAYLWQEVFRKESIANIIQHFIRLDGSSKKQLDKRTLFFPRYHQMDVVR  301

Query  301   KLVNDASENGVGQTYLIQHSAGSGKSNSITWAAYQLIETYPANEGVQGSRGLDQPLFDSV  360
             +LV++ S NGVGQTYLIQHSAGSGKSNSITWAAYQLIETYP ++++ GSRG + PLFDSV
Sbjct  302   RLVDHCSVNGVGQTYLIQHSAGSGKSNSITWAAYQLIETYPISDDLPGSRGKEVPLFDSV  361

Query  361   IVVTDRRLLDKQLRDNIKDFSEVKNIVAPAHKSSELKSALENGKKIIITTIQKFPFIIDG  420
             IVVTDRRLLDKQLRDNIK+FSEVKNIVAPA KSSELKSALENGKKIIITTIQKFP+I+DG
Sbjct  362   IVVTDRRLLDKQLRDNIKEFSEVKNIVAPAFKSSELKSALENGKKIIITTIQKFPYIVDG  421

Query  421   IADLSDKRFAVIIDEAHSSQSGSAHDNMNRAMGKSEVEGAEDAQDKILQAMKSRKMRGNA  480
             IADLSD+RFAVIIDEAHSSQ G  +D++N AMG      +ED  DK LQ+ K+RKMR+NA
Sbjct  422   IADLSDRRFAVIIDEAHSSQDGHNQDKLNEAMGFV----SEDVLDKALQSAKNRKMRSNA  477

Query  481   SYLAFTATPKNTTLEKFGQQQPDGSFEPFHLYTMKQAIEEGFILDVLANYTTYKSYYEIE  540
             SY+AFTATPKNTTLEKFGQ+Q+DG++ PFHLY+MKQAIEEGFILDV+ANYTTYKSYYEIE
Sbjct  478   SYFAFTATPKNTTLEKFGQRQADGTYVPFHLYSMKQAIEEGFILDVIANYTTYKSYYEIE  537

Query  541   KSIQDNPEFDTKKAQKKLRAYVESSQHTIDTKAEIMLEHFVPHVVNAkklkgkgkgMVVT  600
             KSIQDNPEFD+KKAQK+LRAYVE+SQ+TIDTKAEIMLEHF+ HVVN+KKLKGKGKGMVVT
Sbjct  538   KSIQDNPEFDSKKAQKRLRAYVEASQETIDTKAEIMLEHFIKHVVNGKKLKGKGKGMVVT  597

Query  601   QNIETAIRYYKAITRFLEEQGNPFKAVIAFSGEKEVDGIKYTEAEMNGFAENETKDKF--  658
             QNIE+AIRYY+A+T  L+  GNPFK  IAFSG KEVDGI YTEA++NGF+E +TKD F  
Sbjct  598   QNIESAIRYYRALTIQLNKMGNPFKVAIAFSGSKEVDGIEYTEADINGFPEGDTKDYFDV  657

Query  659   ---------------DKDEYRLLVVANKYLTGFDQPKLCAMYVDKKLASVLCVQALSRLN  703
                            D+D YRLLVVANKYLTGFDQPKLCAMYVDKKLASVLCVQALSRLN
Sbjct  658   NYKRKEPDSPIPKHVDQDAYRLLVVANKYLTGFDQPKLCAMYVDKKLASVLCVQALSRLN  717

Query  704   RSAPKLGKKTEDLFVLDFFNSIEEIKTAFDPFYTATSLSEATDVNVLHELKDEMDDVGVY  763
             RSAPK GKKTEDLFVLDFFNS+++IKTAFDPFYT+T+LSEATDVNVLHELKD+MDD GVY
Sbjct  718   RSAPKYGKKTEDLFVLDFFNSVDDIKTAFDPFYTSTTLSEATDVNVLHELKDDMDDTGVY  777

Query  764   EWTEVEEFVKRYFDNEDAQRLSPIIDIAAARFNIELELENEAKIDFKIKAKQFVKIYGQM  823
             EW EVEEF KR+F+  +AQ LSPIIDIAAARFN ELELENE K+DFK+KAKQFVKIYGQ+
Sbjct  778   EWFEVEEFNKRFFEGREAQDLSPIIDIAAARFNHELELENEFKVDFKVKAKQFVKIYGQI  837

Query  824   ASIMSYEIAVWEKLFWFLKFLIPKLKVQdpdaelldelldsvdlssYGLQRVKLSHTIGL  883
             ASIM+YE+  WEKLFWFLKFLIPKL V+DPD E LD LLDSVDLSSYGLQRVKL+H+I L
Sbjct  838   ASIMPYEVVQWEKLFWFLKFLIPKLSVEDPDKEALDSLLDSVDLSSYGLQRVKLNHSIEL  897

Query  884   DGEETELDPQNPNPRGAHGGDKETNPLDDIIYTFNERWFQGWSATPEEQRIKFVNIADSV  943
             D+ ETELDPQNPNPRGA G + E +PLD+II  FNERWFQGWSATPEEQR+KFVNIA+S+
Sbjct  898   DDSETELDPQNPNPRGAYGPEAEKDPLDEIIKIFNERWFQGWSATPEEQRVKFVNIAESI  957

Query  944   KAHPDYEDKYKNNADPHNRELAFEKILKEIMLQRRKDELELYKLFAGDDAFKSSWKQSIQ  1003
             + HPD+E KY+NNADPH RELAFEK+LKEIMLQRRKDELELYKLFA D AFK+SW QS+Q
Sbjct  958   RNHPDFEAKYQNNADPHTRELAFEKMLKEIMLQRRKDELELYKLFAQDPAFKASWTQSMQ  1017

Query  1004  RIVDM  1008
             R+V+M
Sbjct  1018  RMVGM  1022

18) hsdR in NC_010694


> EU272902|14|G13|167832520|ACA01830.1|Vibrio_cholerae_Amazonia_3509|-|13968..17036|-|VPI2_0013c|type 
I restriction enzyme 
HsdR
Length=1022

 Score = 1230 bits (4665),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 758/1022 (75%), Positives = 895/1022 (88%), Gaps = 22/1022 (2%)

Query  1     MVSQTNEQALESAIEKSLVGVSAEERKaglaaqhaaagy-lagsaVDFNKQYALDERLFW  59
             MVS+TNEQALE+AIEK+L G+  EE   G A+ +   +  L GS+ DF+KQYALD RLFW
Sbjct  4     MVSKTNEQALEAAIEKGLAGICKEELALGEAPLNYNNDLYLIGSPSDFDKQYALDTRLFW  63

Query  60    QYLNRTHAPELAKLQKNHPADWQRKLLERYDRlikkhgilhllkkglSVDDAHFNLMFPA  119
             Q+L+ T+A+EL KL++  P DWQRK+LER+DR+I +HG+L+LLKKGL VDDA ++LM+PA
Sbjct  64    QFLEDTQASELEKLKRTSPHDWQRKILERFDRMIMRHGVLRLLKKGLDVDDAFLSLMYPA  123

Query  120   PLASSSEKIKQNFAENIFSCTRQVRYSLGNPLQEIDMVLFINGIPFATLELKNAWTGQTA  179
             PLASSSEK+K++F+ N+FS TRQV YS +NPL+EIDMVLFINGIP+ TLELKN+WTGQ A
Sbjct  124   PLASSSEKVKKDFSANLFSVTRQVCYSNANPLEEIDMVLFINGIPLITLELKNPWTGQNA  183

Query  180   RYHGQKQYCEDRDSTQPLLTFGRCLVHMAVDTDEVYMTTKLAGKSTFFLPFNKGHHHGQG  239
              YHGQKQY +DRD+ QPLL F+RCLVHMAVDTDEVYMTTKLAGK+TFFLPFNKG + G+G
Sbjct  184   VYHGQKQYRDDRDANQPLLNFARCLVHMAVDTDEVYMTTKLAGKNTFFLPFNKGFNFGKG  243

Query  240   NPPNPNGHRTAYLWQAIFTRDSVANIIQHFVRLDGSSKDALAKRTLFFPRYHQLDVVRQL  299
             NP NP+GH+TAYLWQ +F ++S+ANIIQHF+RLDGSSK  L KRTLFFPRYHQ+DVVR+L
Sbjct  244   NPINPHGHKTAYLWQEVFRKESIANIIQHFIRLDGSSKKQLDKRTLFFPRYHQMDVVRRL  303

Query  300   VAHAATYGVGQTYLIQHSAGSGKSNSITWAAYQLIETYPFSAAAAAGKSLEQPLFDSVIV  359
             V H +  GVGQTYLIQHSAGSGKSNSITWAAYQLIETYP+S   +++++ E PLFDSVIV
Sbjct  304   VDHCSVNGVGQTYLIQHSAGSGKSNSITWAAYQLIETYPISDDLPGSRGKEVPLFDSVIV  363

Query  360   VTDRRLLDKQLRDNIKEFSEVKNIIAPAYKSSELKQALESGKKIIITTIQKFPFIIDGIA  419
             VTDRRLLDKQLRDNIKEFSEVKNI+APA+KSSELK ALE+GKKIIITTIQKFP+I+DGIA
Sbjct  364   VTDRRLLDKQLRDNIKEFSEVKNIVAPAFKSSELKSALENGKKIIITTIQKFPYIVDGIA  423

Query  420   DLSDKRFAVIIDEAHSSQSGSAHDNMNRAMGKAQVEEAEDAQDKILQAMNTRKMRGNATY  479
             DLSD+RFAVIIDEAHSSQ G  +D++N AMG      +ED  DK LQ+ + RKMR+NA+Y
Sbjct  424   DLSDRRFAVIIDEAHSSQDGHNQDKLNEAMGFV----SEDVLDKALQSAKNRKMRSNASY  479

Query  480   LAFTATPKNSTLEKFGQCQQDGSFKPFHLYSMKQAIEEGFILDVLANYTTFRSYYEIEKS  539
             +AFTATPKN+TLEKFGQ Q DG++ PFHLYSMKQAIEEGFILDV+ANYTT++SYYEIEKS
Sbjct  480   FAFTATPKNTTLEKFGQRQADGTYVPFHLYSMKQAIEEGFILDVIANYTTYKSYYEIEKS  539

Query  540   IADNPEFDSQKAQKKLRAYVERSQQTIDTKAEIMLEHFVPHIVNAKKLKGKAKGMVITQN  599
             I DNPEFDS+KAQK+LRAYVE SQ+TIDTKAEIMLEHF+ H+VN+KKLKGK+KGMV+TQN
Sbjct  540   IQDNPEFDSKKAQKRLRAYVEASQETIDTKAEIMLEHFIKHVVNGKKLKGKGKGMVVTQN  599

Query  600   IEVAIRYYKAIQRILQQQGNPFKVLIAFSGSKEVDGIEYTEADINGFAENDTKEAF----  655
             IE AIRYY+A+   L++ GNPFKV IAFSGSKEVDGIEYTEADINGF+E DTK+ F    
Sbjct  600   IESAIRYYRALTIQLNKMGNPFKVAIAFSGSKEVDGIEYTEADINGFPEGDTKDYFDVNY  659

Query  656   -------------DSDEFRLLVVANKYLTGFDQPKLCAMYVDKKLTGVLCVQALSRLNRS  702
                          D D +RLLVVANKYLTGFDQPKLCAMYVDKKL++VLCVQALSRLNRS
Sbjct  660   KRKEPDSPIPKHVDQDAYRLLVVANKYLTGFDQPKLCAMYVDKKLASVLCVQALSRLNRS  719

Query  703   APRLGKKTEDLFVLDFFNSVEDVQTAFNPFYTATSLSQATDVNVLHELKDEMDEVGVYEW  762
             AP+ GKKTEDLFVLDFFNSV+D++TAF+PFYT+T+LS+ATDVNVLHELKD+MD+ GVYEW
Sbjct  720   APKYGKKTEDLFVLDFFNSVDDIKTAFDPFYTSTTLSEATDVNVLHELKDDMDDTGVYEW  779

Query  763   YEVEDFVVRYFNNEDAQTLSPIIDRATARFESELELEPEQKIDFKIKAKQFVKIYGQMAS  822
             +EVE+F  R+F+  +AQ LSPIID A+ARF+ ELELE E K+DFK+KAKQFVKIYGQ+AS
Sbjct  780   FEVEEFNKRFFEGREAQDLSPIIDIAAARFNHELELENEFKVDFKVKAKQFVKIYGQIAS  839

Query  823   IMPYEIVAWEKLFWFLKFLIPKLIVEDPDADAFDKLLESVDLSSYGLQRVRLGHGIRLDA  882
             IMPYE+V WEKLFWFLKFLIPKL VEDPD +A+D LL+SVDLSSYGLQRV+L H+I LD 
Sbjct  840   IMPYEVVQWEKLFWFLKFLIPKLSVEDPDKEALDSLLDSVDLSSYGLQRVKLNHSIELDD  899

Query  883   AETEVDPQNPNPRGAYGTEREADPLDDIIRNFNERWFQGWSATPEEQKVKFVNMVNSVRS  942
             +ETE+DPQNPNPRGAYG E E DPLD+II+ FNERWFQGWSATPEEQ+VKFVN+ +S+R+
Sbjct  900   SETELDPQNPNPRGAYGPEAEKDPLDEIIKIFNERWFQGWSATPEEQRVKFVNIAESIRN  959

Query  943   HPDFAAKYQNNPDPHNRQLAFDKMLREIMLLRRKDELELYKLYANDPAFKASLTQSMQHM  1002
             HPDF AKYQNN+DPH R+LAF+KML+EIML RRKDELELYKL+A+DPAFKAS TQSMQ+M
Sbjct  960   HPDFEAKYQNNADPHTRELAFEKMLKEIMLQRRKDELELYKLFAQDPAFKASWTQSMQRM  1019

Query  1003  LD  1004
             ++
Sbjct  1020  VG  1021

19) Tola_2270 in NC_012691


> EU272902|14|G13|167832520|ACA01830.1|Vibrio_cholerae_Amazonia_3509|-|13968..17036|-|VPI2_0013c|type 
I restriction enzyme 
HsdR
Length=1022

 Score = 1227 bits (4655),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 777/1026 (76%), Positives = 907/1026 (89%), Gaps = 24/1026 (2%)

Query  1     MVSHTNEQALEAAIEKALTGLCMEEVKAGINEPAGAYITQHNGFQQGFPADIDKQYALDL  60
             MVS TNEQALEAAIEK+L+G+C EE+  ++ E++  Y  +++ +  G P+D+DKQYALD 
Sbjct  4     MVSKTNEQALEAAIEKGLAGICKEEL--ALGEAPLNY--NNDLYLIGSPSDFDKQYALDT  59

Query  61    RLFWQFLENTQAEELAKLKVHHANDWQRKVLERFDRLIkkhgvlhllkkglSVDDAYLTL  120
             RLFWQFLE+TQA EL KLK   ++DWQRK+LERFDR+I +HGVL+LLKKGL VDDA+L+L
Sbjct  60    RLFWQFLEDTQASELEKLKRTSPHDWQRKILERFDRMIMRHGVLRLLKKGLDVDDAFLSL  119

Query  121   MYPAPLASSSQAVKQNFTANIFSCTRQVCYSQLNPLQEIDMVLFINGIPLVTLELKNAWT  180
             MYPAPLASSS+ VK++F+AN+FS TRQVCYS+ NPL+EIDMVLFINGIPL+TLELKN+WT
Sbjct  120   MYPAPLASSSEKVKKDFSANLFSVTRQVCYSNANPLEEIDMVLFINGIPLITLELKNPWT  179

Query  181   GQTARYHGQKQYREDRDINQPLLNFGRCLVHMAVDTDEVYMTTKLAGKETFFLPFNKGNN  240
             GQ A YHGQKQYR+DRD NQPLLNF+RCLVHMAVDTDEVYMTTKLAGK+TFFLPFNKG N
Sbjct  180   GQNAVYHGQKQYRDDRDANQPLLNFARCLVHMAVDTDEVYMTTKLAGKNTFFLPFNKGFN  239

Query  241   HGQGNPPNLFGHKTAYLWEEVFTKVSLANIIQHFVRLDGSSKDLLNKRTLFFPRYHQLDV  300
              G+GNP N  GHKTAYLW+EVF K S+ANIIQHF+RLDGSSK  L+KRTLFFPRYHQ+DV
Sbjct  240   FGKGNPINPHGHKTAYLWQEVFRKESIANIIQHFIRLDGSSKKQLDKRTLFFPRYHQMDV  299

Query  301   VRRLVDHAAHYGVGHTYLIQHSAGSGKSNSITWAAYQLIEAYPATNDVHGSHGIDQPLFD  360
             VRRLVDH +  GVG+TYLIQHSAGSGKSNSITWAAYQLIE+YP ++D+ GS+G + PLFD
Sbjct  300   VRRLVDHCSVNGVGQTYLIQHSAGSGKSNSITWAAYQLIETYPISDDLPGSRGKEVPLFD  359

Query  361   SVIVVTDRRLLDKQLRENIKEFSEVKNIIAPANKSSELKSALENGKKIIITTIQKFPFIV  420
             SVIVVTDRRLLDKQLR+NIKEFSEVKNI+APA KSSELKSALENGKKIIITTIQKFP+IV
Sbjct  360   SVIVVTDRRLLDKQLRDNIKEFSEVKNIVAPAFKSSELKSALENGKKIIITTIQKFPYIV  419

Query  421   DGISDLSDKRFAVIIDEAHSSQSGTAHSKMNEAMGKTEEEAEDIQDLILQSMLSRKMRGN  480
             DGI+DLSD+RFAVIIDEAHSSQ G  + K+NEAMG     +ED+ D  LQS  +RKMR+N
Sbjct  420   DGIADLSDRRFAVIIDEAHSSQDGHNQDKLNEAMGFV---SEDVLDKALQSAKNRKMRSN  476

Query  481   ASYLAFTATPKNTTLEKFGQRQEDGSYRPFHLYSMKQAIEEGFILDVVANYTTYRSYYEI  540
             ASY+AFTATPKNTTLEKFGQRQ DG+Y PFHLYSMKQAIEEGFILDV+ANYTTY+SYYEI
Sbjct  477   ASYFAFTATPKNTTLEKFGQRQADGTYVPFHLYSMKQAIEEGFILDVIANYTTYKSYYEI  536

Query  541   SKSVEDNPQFDSKKAQKKLRAYVEGSQETINVKAEIMLEHFIPHVVNAkklkgkgkgMVV  600
              KS++DNP+FDSKKAQK+LRAYVE+SQETI+ KAEIMLEHFI HVVN+KKLKGKGKGMVV
Sbjct  537   EKSIQDNPEFDSKKAQKRLRAYVEASQETIDTKAEIMLEHFIKHVVNGKKLKGKGKGMVV  596

Query  601   TQNIVSAIRYFKAITKQLDAIGNPFKVLIAFSGTKEVDGIEYTEADLNGFAENDTRDKFD  660
             TQNI SAIRY++A+T QL+ +GNPFKV IAFSG+KEVDGIEYTEAD+NGF+E DT+D FD
Sbjct  597   TQNIESAIRYYRALTIQLNKMGNPFKVAIAFSGSKEVDGIEYTEADINGFPEGDTKDYFD  656

Query  661   T-----------------DEYRLLIVANKYLTGFDQPKLCAMYVDKKLAGVLCVQALSRL  703
                               D YRLL+VANKYLTGFDQPKLCAMYVDKKLA+VLCVQALSRL
Sbjct  657   VNYKRKEPDSPIPKHVDQDAYRLLVVANKYLTGFDQPKLCAMYVDKKLASVLCVQALSRL  716

Query  704   NRAAPKWGKKTEDLFILDFFNAVDDIKAAFDPFYTATSLSQATDINVLHELKDALDDVGV  763
             NR+APK GKKTEDLF+LDFFN+VDDIK+AFDPFYT+T+LS+ATD+NVLHELKD +DD GV
Sbjct  717   NRSAPKYGKKTEDLFVLDFFNSVDDIKTAFDPFYTSTTLSEATDVNVLHELKDDMDDTGV  776

Query  764   YEWYEVEEFVQRYFKGDDAQLLSGIIDVAAERFNQELELTNAEQVDFKIKAKQFVKIYGQ  823
             YEW+EVEEF +R+F G +AQ LS IID+AA RFN+ELEL N  +VDFK+KAKQFVKIYGQ
Sbjct  777   YEWFEVEEFNKRFFEGREAQDLSPIIDIAAARFNHELELENEFKVDFKVKAKQFVKIYGQ  836

Query  824   MASIIPYDMllweklfwflkflIPKLKVQDPESDLLDELLNSVDLASYGLQRVKLNYTID  883
             +ASI+PY+++ WEKLFWFLKFLIPKL V+DP+ + LD LL+SVDL+SYGLQRVKLN +I+
Sbjct  837   IASIMPYEVVQWEKLFWFLKFLIPKLSVEDPDKEALDSLLDSVDLSSYGLQRVKLNHSIE  896

Query  884   LDAQETTVDPQNPNPRGGHGGDVETDPLDAIINNFNEKWFQGWSSTPEEQKVKFVNIADS  943
             LD  ET +DPQNPNPRG+ G + E DPLD II+ FNE+WFQGWS+TPEEQ+VKFVNIA+S
Sbjct  897   LDDSETELDPQNPNPRGAYGPEAEKDPLDEIIKIFNERWFQGWSATPEEQRVKFVNIAES  956

Query  944   VKKHPDFEAKYQNNPDPINRELAFEKILKEVMLLRRKDELELYKLFANDAAFKTSWMQSV  1003
             +++HPDFEAKYQNN+DP  RELAFEK+LKE+ML RRKDELELYKLFA+D+AFK+SW QS+
Sbjct  957   IRNHPDFEAKYQNNADPHTRELAFEKMLKEIMLQRRKDELELYKLFAQDPAFKASWTQSM  1016

Query  1004  QRMVGV  1009
             QRMVG+
Sbjct  1017  QRMVGM  1022

20) NT01EI_2502 in NC_012779


> EU272902|14|G13|167832520|ACA01830.1|Vibrio_cholerae_Amazonia_3509|-|13968..17036|-|VPI2_0013c|type 
I restriction enzyme 
HsdR
Length=1022

 Score = 1221 bits (4632),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 760/1027 (75%), Positives = 893/1027 (87%), Gaps = 25/1027 (2%)

Query  1     MVSNTKeqaleaaieqalTGQCLETLGNGIGEGAAVYTIPHHGFVLGQACDFDKQYAIDK  60
             MVS+T+EQALEAAIE++L+G C E L+  +GE++  Y   ++ +++G + DFDKQYA+D 
Sbjct  4     MVSKTNEQALEAAIEKGLAGICKEELA--LGEAPLNYN--NDLYLIGSPSDFDKQYALDT  59

Query  61    RLFWQFLETTQAMELAKLQQHHPQDWQRKVLERFDRIIKKQGVLHLLKKGLSVDDAHLTL  120
             RLFWQFLE TQA EL KL++  P+DWQRK+LERFDR+I ++GVL+LLKKGL VDDA L+L
Sbjct  60    RLFWQFLEDTQASELEKLKRTSPHDWQRKILERFDRMIMRHGVLRLLKKGLDVDDAFLSL  119

Query  121   MYPAPLASSSATVSQNFAANLFSCTRQVAYSAQNPKQEIDIVLFINGIPLITLELKNHWT  180
             MYPAPLASSS  V ++F+ANLFS TRQV YS  NP +EID+VLFINGIPLITLELKN WT
Sbjct  120   MYPAPLASSSEKVKKDFSANLFSVTRQVCYSNANPLEEIDMVLFINGIPLITLELKNPWT  179

Query  181   GQNASYHGQKQYREDRDISQPLLHFGRALVHMAVDTDEVYMTTKLAGKATFFLPFNQGHR  240
             GQNA YHGQKQYR+DRD +QPLL+F+R LVHMAVDTDEVYMTTKLAGK TFFLPFN+G  
Sbjct  180   GQNAVYHGQKQYRDDRDANQPLLNFARCLVHMAVDTDEVYMTTKLAGKNTFFLPFNKGFN  239

Query  241   HGKGNPPNPYGHKSAYLWQEVFSKESLANIIQHFVRLDGSTKELLNKRTLFFPRYHQLDV  300
              GKGNP NP GHK+AYLWQEVF KES+ANIIQHF+RLDGS+K  L+KRTLFFPRYHQ+DV
Sbjct  240   FGKGNPINPHGHKTAYLWQEVFRKESIANIIQHFIRLDGSSKKQLDKRTLFFPRYHQMDV  299

Query  301   VRKLVDHAAQHGVGQTYLIQHSAGSGKSNSITWAAYQLIEVYPHSADVQGAKAVDQPLFD  360
             VR+LVDH + +GVGQTYLIQHSAGSGKSNSITWAAYQLIE YP S D+ G+++ + PLFD
Sbjct  300   VRRLVDHCSVNGVGQTYLIQHSAGSGKSNSITWAAYQLIETYPISDDLPGSRGKEVPLFD  359

Query  361   SIIVVTDRRLLDKQLRENIKEFSEVKNIIAPANKSSELKSALENGKKIIITTIQKFPFIV  420
             S+IVVTDRRLLDKQLR+NIKEFSEVKNI+APA KSSELKSALENGKKIIITTIQKFP+IV
Sbjct  360   SVIVVTDRRLLDKQLRDNIKEFSEVKNIVAPAFKSSELKSALENGKKIIITTIQKFPYIV  419

Query  421   DGISDLSDKRFAVIIDEAHSSQSGDAHGKMNAAMGKKQEEEMEDTQDLILQAMRSRKMCG  480
             DGI+DLSD+RFAVIIDEAHSSQ G+ ++K+N AMG   E+ ++ +    LQ+ ++RKM +
Sbjct  420   DGIADLSDRRFAVIIDEAHSSQDGHNQDKLNEAMGFVSEDVLDKA----LQSAKNRKMRS  475

Query  481   NASYFAFTATPKNTTLEKFGQLQPDGTFQPFHLYSMKQAIEEGFILDVLANYTTYCSYYE  540
             NASYFAFTATPKNTTLEKFGQ Q+DGT+ PFHLYSMKQAIEEGFILDV+ANYTTY SYYE
Sbjct  476   NASYFAFTATPKNTTLEKFGQRQADGTYVPFHLYSMKQAIEEGFILDVIANYTTYKSYYE  535

Query  541   IRKSIDENPLFDSKKAQKKLRAYVEGSQETIDVKAEIMLEHFIPHVVNAkklkgkgkgMV  600
             I KSI++NP FDSKKAQK+LRAYVE+SQETID KAEIMLEHFI HVVN+KKLKGKGKGMV
Sbjct  536   IEKSIQDNPEFDSKKAQKRLRAYVEASQETIDTKAEIMLEHFIKHVVNGKKLKGKGKGMV  595

Query  601   VTQSIVSAIRYYRAITRQLEAVGNPFKVLIAFSGSKEVDGVEYTEAELNGFAEGDTRDKF  660
             VTQ+I SAIRYYRA+T QL+ +GNPFKV IAFSGSKEVDG+EYTEA++NGF+EGDT+D F
Sbjct  596   VTQNIESAIRYYRALTIQLNKMGNPFKVAIAFSGSKEVDGIEYTEADINGFPEGDTKDYF  655

Query  661   DT-----------------DEYRLLIVANKYLTGFDQPKLCTMYVDKKMSGVLCVQALSR  703
             D                  D YRLL+VANKYLTGFDQPKLC+MYVDKK+++VLCVQALSR
Sbjct  656   DVNYKRKEPDSPIPKHVDQDAYRLLVVANKYLTGFDQPKLCAMYVDKKLASVLCVQALSR  715

Query  704   LNRAAPKWGKKTEDLFILDFFNPVEAIKASFDPFYTATSLSGATDINVLHELKDALDDTG  763
             LNR+APK GKKTEDLF+LDFFN+V+ IK++FDPFYT+T+LS ATD+NVLHELKD +DDTG
Sbjct  716   LNRSAPKYGKKTEDLFVLDFFNSVDDIKTAFDPFYTSTTLSEATDVNVLHELKDDMDDTG  775

Query  764   VYEWLEVEKFVARYFNNEDAQLLSAIIDVAADRFNHELELSNEEKADIKIKAKQFVKIYG  823
             VYEW+EVE F  R+F+  +AQ LS+IID+AA RFNHELEL NE K D+K+KAKQFVKIYG
Sbjct  776   VYEWFEVEEFNKRFFEGREAQDLSPIIDIAAARFNHELELENEFKVDFKVKAKQFVKIYG  835

Query  824   QMAAIMPYDMLTWEKLFWFLKFLIPKLKVQdpdtdlldellesvdlssYGLQRVKLNHAI  883
             Q+A+IMPY+++ WEKLFWFLKFLIPKL V+DPD + LD LL+SVDLSSYGLQRVKLNH+I
Sbjct  836   QIASIMPYEVVQWEKLFWFLKFLIPKLSVEDPDKEALDSLLDSVDLSSYGLQRVKLNHSI  895

Query  884   TLDADESVLDPQNSNPRGVHGSGEETDPLDEIIKSFNEKWFQGWSSTPEEQRVKFVNILD  943
              LD  E+ LDPQN+NPRG  G+  E DPLDEIIK FNE+WFQGWS+TPEEQRVKFVNI +
Sbjct  896   ELDDSETELDPQNPNPRGAYGPEAEKDPLDEIIKIFNERWFQGWSATPEEQRVKFVNIAE  955

Query  944   NVKKHPDFESKYQNNSDPINRELAFEKIMREVMLARRKDELALYKLFANDPAFKESWMQS  1003
             ++++HPDFE+KYQNN+DP  RELAFEK+++E+ML RRKDEL LYKLFA+DPAFK SW QS
Sbjct  956   SIRNHPDFEAKYQNNADPHTRELAFEKMLKEIMLQRRKDELELYKLFAQDPAFKASWTQS  1015

Query  1004  AQRMVGM  1010
              QRMVGM
Sbjct  1016  MQRMVGM  1022

21) hsdR in NC_017390


> EU272902|14|G13|167832520|ACA01830.1|Vibrio_cholerae_Amazonia_3509|-|13968..17036|-|VPI2_0013c|type 
I restriction enzyme 
HsdR
Length=1022

 Score = 1199 bits (4547),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 755/1022 (74%), Positives = 894/1022 (88%), Gaps = 22/1022 (2%)

Query  1     MVSQTNEQALESAIEKSLVGISAEERKAGVVaqhaaagy-lagaaaDFNRQYALDERFFW  59
             MVS+TNEQALE+AIEK+L GI  EE   G  + +   +  L G+++DF++QYALD R+FW
Sbjct  4     MVSKTNEQALEAAIEKGLAGICKEELALGEAPLNYNNDLYLIGSPSDFDKQYALDTRLFW  63

Query  60    QYLQQTHAPELAKLQKHHPADWQRKLLERYDRLIkkhgvlhllkkglSVDDAHFNLMFPA  119
             Q+L++T+A+EL KL++  P DWQRK+LER+DR+I +HGVL+LLKKGL VDDA ++LM+PA
Sbjct  64    QFLEDTQASELEKLKRTSPHDWQRKILERFDRMIMRHGVLRLLKKGLDVDDAFLSLMYPA  123

Query  120   PLASSGEKIKQNFAENRFSCTRQVRYSLGNPLQEIDMVLFINGIPFATLELKNAWTGQTA  179
             PLASS+EK+K++F+ N FS TRQV YS +NPL+EIDMVLFINGIP+ TLELKN+WTGQ A
Sbjct  124   PLASSSEKVKKDFSANLFSVTRQVCYSNANPLEEIDMVLFINGIPLITLELKNPWTGQNA  183

Query  180   RYHGQKQYCEDRDSSQALLTFGRCLVHMAVDTDEVYMTTKLAGKSTFFLPFNKGHHHGQG  239
              YHGQKQY +DRD++Q+LL F+RCLVHMAVDTDEVYMTTKLAGK+TFFLPFNKG + G+G
Sbjct  184   VYHGQKQYRDDRDANQPLLNFARCLVHMAVDTDEVYMTTKLAGKNTFFLPFNKGFNFGKG  243

Query  240   NPPNPNGHRTAYLWQEIFTRDSVANIIQHFVRLDGSSKDSLAKRTLFFPRYHQLDVVRQL  299
             NP NP+GH+TAYLWQE+F ++S+ANIIQHF+RLDGSSK  L KRTLFFPRYHQ+DVVR+L
Sbjct  244   NPINPHGHKTAYLWQEVFRKESIANIIQHFIRLDGSSKKQLDKRTLFFPRYHQMDVVRRL  303

Query  300   VAHAATYGVGQTYLIQHSAGSGKSNSITWAAYQLIETCPLSAAAAAGKSLEQPLFDSVIV  359
             V H +  GVGQTYLIQHSAGSGKSNSITWAAYQLIET P+S   +++++ E PLFDSVIV
Sbjct  304   VDHCSVNGVGQTYLIQHSAGSGKSNSITWAAYQLIETYPISDDLPGSRGKEVPLFDSVIV  363

Query  360   VTDRRLLDKQLRDNIKEFSEVKNIIAPAYKSSELKQALESGKKIIITTIQKFPFIIDGIA  419
             VTDRRLLDKQLRDNIKEFSEVKNI+APA+KSSELK ALE+GKKIIITTIQKFP+I+DGIA
Sbjct  364   VTDRRLLDKQLRDNIKEFSEVKNIVAPAFKSSELKSALENGKKIIITTIQKFPYIVDGIA  423

Query  420   DLSDKRFAVIIDEAHSSQSGSAHDNMNRAMGKAQVEEAEDAQDKILQAMNSRKMRGNATY  479
             DLSD+RFAVIIDEAHSSQ G  +D++N AMG      +ED  DK LQ+ ++RKMR+NA+Y
Sbjct  424   DLSDRRFAVIIDEAHSSQDGHNQDKLNEAMGFV----SEDVLDKALQSAKNRKMRSNASY  479

Query  480   LAFTATPKNSTLEKFGQCQQDGTFKPFHLYSMKQAIEEGFILDVLANYTTFRSYYEIEKS  539
             +AFTATPKN+TLEKFGQ Q DGT+ PFHLYSMKQAIEEGFILDV+ANYTT++SYYEIEKS
Sbjct  480   FAFTATPKNTTLEKFGQRQADGTYVPFHLYSMKQAIEEGFILDVIANYTTYKSYYEIEKS  539

Query  540   IADNPEFDSQKAQKKLRAYVERSQQTIDTKAGIMLEHFVPHIVNAKKLKGKAKGMVVTQN  599
             I DNPEFDS+KAQK+LRAYVE SQ+TIDTKA IMLEHF+ H+VN+KKLKGK+KGMVVTQN
Sbjct  540   IQDNPEFDSKKAQKRLRAYVEASQETIDTKAEIMLEHFIKHVVNGKKLKGKGKGMVVTQN  599

Query  600   IEVAIRYYKAIQRILQQQGNPFKVLIAFSGSKEVDGIEYTEADINGFAENDTKEAF----  655
             IE AIRYY+A+   L++ GNPFKV IAFSGSKEVDGIEYTEADINGF+E DTK+ F    
Sbjct  600   IESAIRYYRALTIQLNKMGNPFKVAIAFSGSKEVDGIEYTEADINGFPEGDTKDYFDVNY  659

Query  656   -------------DSDEYRLLVVANKYLTGFDQPKLCAMYVDKKLTGVLCVQALSRLNRS  702
                          D D YRLLVVANKYLTGFDQPKLCAMYVDKKL++VLCVQALSRLNRS
Sbjct  660   KRKEPDSPIPKHVDQDAYRLLVVANKYLTGFDQPKLCAMYVDKKLASVLCVQALSRLNRS  719

Query  703   APRLGKKTEDLFVLDFFNSVEDVQAAFNPFYTATSLSRATDVNVLHELKDEMDDAGVYEW  762
             AP+ GKKTEDLFVLDFFNSV+D+++AF+PFYT+T+LS ATDVNVLHELKD+MDD+GVYEW
Sbjct  720   APKYGKKTEDLFVLDFFNSVDDIKTAFDPFYTSTTLSEATDVNVLHELKDDMDDTGVYEW  779

Query  763   YEVEDFVARYFNNEDAQTLSPVIDRAAARFASELELEPEQKIDFKVKAKQFVKIYGQMAS  822
             +EVE+F  R+F+  +AQ LSP+ID AAARF  ELELE E K+DFKVKAKQFVKIYGQ+AS
Sbjct  780   FEVEEFNKRFFEGREAQDLSPIIDIAAARFNHELELENEFKVDFKVKAKQFVKIYGQIAS  839

Query  823   IMPYEMVAWEKLFWFLKFLIPKLIVEDPDADAFDKLLESVNLSSYGLQRVKLGHGIKLDA  882
             IMPYE+V WEKLFWFLKFLIPKL VEDPD +A+D LL+SV+LSSYGLQRVKL H+I LD 
Sbjct  840   IMPYEVVQWEKLFWFLKFLIPKLSVEDPDKEALDSLLDSVDLSSYGLQRVKLNHSIELDD  899

Query  883   AETEVDPQNPNPRGAYGTERETDPLDEIIRNFNERWFHGWRATPEEQKIKFVNMVNSVRN  942
             +ETE+DPQNPNPRGAYG E E DPLDEII+ FNERWF+GW ATPEEQ++KFVN+ +S+RN
Sbjct  900   SETELDPQNPNPRGAYGPEAEKDPLDEIIKIFNERWFQGWSATPEEQRVKFVNIAESIRN  959

Query  943   HPDFAAKYQNNPDPHNRQLAFDKMLKEVMllrrkeelelyklyANDPAFKASLTQSMQHM  1002
             HPDF AKYQNN+DPH R+LAF+KMLKE+ML RRK+ELELYKL+A+DPAFKAS TQSMQ+M
Sbjct  960   HPDFEAKYQNNADPHTRELAFEKMLKEIMLQRRKDELELYKLFAQDPAFKASWTQSMQRM  1019

Query  1003  LD  1004
             ++
Sbjct  1020  VG  1021

22) EpC_35290 in NC_012214


> EU272902|14|G13|167832520|ACA01830.1|Vibrio_cholerae_Amazonia_3509|-|13968..17036|-|VPI2_0013c|type 
I restriction enzyme 
HsdR
Length=1022

 Score = 1199 bits (4547),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 755/1022 (74%), Positives = 894/1022 (88%), Gaps = 22/1022 (2%)

Query  1     MVSQTNEQALESAIEKSLVGISAEERKAGVVaqhaaagy-lagaaaDFNRQYALDERFFW  59
             MVS+TNEQALE+AIEK+L GI  EE   G  + +   +  L G+++DF++QYALD R+FW
Sbjct  4     MVSKTNEQALEAAIEKGLAGICKEELALGEAPLNYNNDLYLIGSPSDFDKQYALDTRLFW  63

Query  60    QYLQQTHAPELAKLQKHHPADWQRKLLERYDRLIkkhgvlhllkkglSVDDAHFNLMFPA  119
             Q+L++T+A+EL KL++  P DWQRK+LER+DR+I +HGVL+LLKKGL VDDA ++LM+PA
Sbjct  64    QFLEDTQASELEKLKRTSPHDWQRKILERFDRMIMRHGVLRLLKKGLDVDDAFLSLMYPA  123

Query  120   PLASSGEKIKQNFAENRFSCTRQVRYSLGNPLQEIDMVLFINGIPFATLELKNAWTGQTA  179
             PLASS+EK+K++F+ N FS TRQV YS +NPL+EIDMVLFINGIP+ TLELKN+WTGQ A
Sbjct  124   PLASSSEKVKKDFSANLFSVTRQVCYSNANPLEEIDMVLFINGIPLITLELKNPWTGQNA  183

Query  180   RYHGQKQYCEDRDSSQALLTFGRCLVHMAVDTDEVYMTTKLAGKSTFFLPFNKGHHHGQG  239
              YHGQKQY +DRD++Q+LL F+RCLVHMAVDTDEVYMTTKLAGK+TFFLPFNKG + G+G
Sbjct  184   VYHGQKQYRDDRDANQPLLNFARCLVHMAVDTDEVYMTTKLAGKNTFFLPFNKGFNFGKG  243

Query  240   NPPNPNGHRTAYLWQEIFTRDSVANIIQHFVRLDGSSKDSLAKRTLFFPRYHQLDVVRQL  299
             NP NP+GH+TAYLWQE+F ++S+ANIIQHF+RLDGSSK  L KRTLFFPRYHQ+DVVR+L
Sbjct  244   NPINPHGHKTAYLWQEVFRKESIANIIQHFIRLDGSSKKQLDKRTLFFPRYHQMDVVRRL  303

Query  300   VAHAATYGVGQTYLIQHSAGSGKSNSITWAAYQLIETCPLSAAAAAGKSLEQPLFDSVIV  359
             V H +  GVGQTYLIQHSAGSGKSNSITWAAYQLIET P+S   +++++ E PLFDSVIV
Sbjct  304   VDHCSVNGVGQTYLIQHSAGSGKSNSITWAAYQLIETYPISDDLPGSRGKEVPLFDSVIV  363

Query  360   VTDRRLLDKQLRDNIKEFSEVKNIIAPAYKSSELKQALESGKKIIITTIQKFPFIIDGIA  419
             VTDRRLLDKQLRDNIKEFSEVKNI+APA+KSSELK ALE+GKKIIITTIQKFP+I+DGIA
Sbjct  364   VTDRRLLDKQLRDNIKEFSEVKNIVAPAFKSSELKSALENGKKIIITTIQKFPYIVDGIA  423

Query  420   DLSDKRFAVIIDEAHSSQSGSAHDNMNRAMGKAQVEEAEDAQDKILQAMNSRKMRGNATY  479
             DLSD+RFAVIIDEAHSSQ G  +D++N AMG      +ED  DK LQ+ ++RKMR+NA+Y
Sbjct  424   DLSDRRFAVIIDEAHSSQDGHNQDKLNEAMGFV----SEDVLDKALQSAKNRKMRSNASY  479

Query  480   LAFTATPKNSTLEKFGQCQQDGTFKPFHLYSMKQAIEEGFILDVLANYTTFRSYYEIEKS  539
             +AFTATPKN+TLEKFGQ Q DGT+ PFHLYSMKQAIEEGFILDV+ANYTT++SYYEIEKS
Sbjct  480   FAFTATPKNTTLEKFGQRQADGTYVPFHLYSMKQAIEEGFILDVIANYTTYKSYYEIEKS  539

Query  540   IADNPEFDSQKAQKKLRAYVERSQQTIDTKAGIMLEHFVPHIVNAKKLKGKAKGMVVTQN  599
             I DNPEFDS+KAQK+LRAYVE SQ+TIDTKA IMLEHF+ H+VN+KKLKGK+KGMVVTQN
Sbjct  540   IQDNPEFDSKKAQKRLRAYVEASQETIDTKAEIMLEHFIKHVVNGKKLKGKGKGMVVTQN  599

Query  600   IEVAIRYYKAIQRILQQQGNPFKVLIAFSGSKEVDGIEYTEADINGFAENDTKEAF----  655
             IE AIRYY+A+   L++ GNPFKV IAFSGSKEVDGIEYTEADINGF+E DTK+ F    
Sbjct  600   IESAIRYYRALTIQLNKMGNPFKVAIAFSGSKEVDGIEYTEADINGFPEGDTKDYFDVNY  659

Query  656   -------------DSDEYRLLVVANKYLTGFDQPKLCAMYVDKKLTGVLCVQALSRLNRS  702
                          D D YRLLVVANKYLTGFDQPKLCAMYVDKKL++VLCVQALSRLNRS
Sbjct  660   KRKEPDSPIPKHVDQDAYRLLVVANKYLTGFDQPKLCAMYVDKKLASVLCVQALSRLNRS  719

Query  703   APRLGKKTEDLFVLDFFNSVEDVQAAFNPFYTATSLSRATDVNVLHELKDEMDDAGVYEW  762
             AP+ GKKTEDLFVLDFFNSV+D+++AF+PFYT+T+LS ATDVNVLHELKD+MDD+GVYEW
Sbjct  720   APKYGKKTEDLFVLDFFNSVDDIKTAFDPFYTSTTLSEATDVNVLHELKDDMDDTGVYEW  779

Query  763   YEVEDFVARYFNNEDAQTLSPVIDRAAARFASELELEPEQKIDFKVKAKQFVKIYGQMAS  822
             +EVE+F  R+F+  +AQ LSP+ID AAARF  ELELE E K+DFKVKAKQFVKIYGQ+AS
Sbjct  780   FEVEEFNKRFFEGREAQDLSPIIDIAAARFNHELELENEFKVDFKVKAKQFVKIYGQIAS  839

Query  823   IMPYEMVAWEKLFWFLKFLIPKLIVEDPDADAFDKLLESVNLSSYGLQRVKLGHGIKLDA  882
             IMPYE+V WEKLFWFLKFLIPKL VEDPD +A+D LL+SV+LSSYGLQRVKL H+I LD 
Sbjct  840   IMPYEVVQWEKLFWFLKFLIPKLSVEDPDKEALDSLLDSVDLSSYGLQRVKLNHSIELDD  899

Query  883   AETEVDPQNPNPRGAYGTERETDPLDEIIRNFNERWFHGWRATPEEQKIKFVNMVNSVRN  942
             +ETE+DPQNPNPRGAYG E E DPLDEII+ FNERWF+GW ATPEEQ++KFVN+ +S+RN
Sbjct  900   SETELDPQNPNPRGAYGPEAEKDPLDEIIKIFNERWFQGWSATPEEQRVKFVNIAESIRN  959

Query  943   HPDFAAKYQNNPDPHNRQLAFDKMLKEVMllrrkeelelyklyANDPAFKASLTQSMQHM  1002
             HPDF AKYQNN+DPH R+LAF+KMLKE+ML RRK+ELELYKL+A+DPAFKAS TQSMQ+M
Sbjct  960   HPDFEAKYQNNADPHTRELAFEKMLKEIMLQRRKDELELYKLFAQDPAFKASWTQSMQRM  1019

Query  1003  LD  1004
             ++
Sbjct  1020  VG  1021

23) MEALZ_3679 in NC_016112


> EU272902|14|G13|167832520|ACA01830.1|Vibrio_cholerae_Amazonia_3509|-|13968..17036|-|VPI2_0013c|type 
I restriction enzyme 
HsdR
Length=1022

 Score = 1197 bits (4540),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 736/983 (75%), Positives = 858/983 (88%), Gaps = 21/983 (2%)

Query  45    YVAGIPADFNMQYAIDERFFWQFLEKTQEQELAKLQKNNPGDWQRKLLERYDRlikkhgi  104
             Y+ G P+DF+ QYA+D R+FWQFLE TQ  EL KL++ +P DWQRK+LER+DR+I +HG+
Sbjct  43    YLIGSPSDFDKQYALDTRLFWQFLEDTQASELEKLKRTSPHDWQRKILERFDRMIMRHGV  102

Query  105   lhllkkglSVDDAHFNLLYPAPLASSSEKVTQNFANNIFSCTRQVRYSLANPLQEIDMVL  164
             L+LLKKGL VDDA ++L+YPAPLASSSEKV ++F+ N+FS TRQV YS ANPL+EIDMVL
Sbjct  103   LRLLKKGLDVDDAFLSLMYPAPLASSSEKVKKDFSANLFSVTRQVCYSNANPLEEIDMVL  162

Query  165   FINGIPLVTLELKNAWTGQTARYHGLKQYREDRDTTQPLLTFGRCLVHMAVDTDEVYMTT  224
             FINGIPL+TLELKN+WTGQ A YHG KQYR+DRD+ QPLL F+RCLVHMAVDTDEVYMTT
Sbjct  163   FINGIPLITLELKNPWTGQNAVYHGQKQYRDDRDANQPLLNFARCLVHMAVDTDEVYMTT  222

Query  225   KLAGESTFFLPFNKGHNLGQGNPPNPQGHKTAYLWEEIFTKDSIVNIIQHFVRLDGGSKD  284
             KLAG +TFFLPFNKG N+G+GNP NP+GHKTAYLW+E+F K+SI NIIQHF+RLDG+SK 
Sbjct  223   KLAGKNTFFLPFNKGFNFGKGNPINPHGHKTAYLWQEVFRKESIANIIQHFIRLDGSSKK  282

Query  285   PLPKRTLFFPRYHQLDVVRKLVDHASNNGVGQTYLIQHSAGSGKSNSITWAAYQLIETYP  344
              L KRTLFFPRYHQ+DVVR+LVDH S NGVGQTYLIQHSAGSGKSNSITWAAYQLIETYP
Sbjct  283   QLDKRTLFFPRYHQMDVVRRLVDHCSVNGVGQTYLIQHSAGSGKSNSITWAAYQLIETYP  342

Query  345   ASEAVSGGKGLEQPLFDSVIVVTDRRLLDKQLRDNIKEFSEVKNIIAPAHKSSELKQALE  404
              S+ ++G++G E PLFDSVIVVTDRRLLDKQLRDNIKEFSEVKNI+APA KSSELK ALE
Sbjct  343   ISDDLPGSRGKEVPLFDSVIVVTDRRLLDKQLRDNIKEFSEVKNIVAPAFKSSELKSALE  402

Query  405   NGKKIIITTIQKFPFIIDGISDLSDKRFAVIIDEAHSSQSGSAHDSMNRAMGRTDVEEAE  464
             NGKKIIITTIQKFP+I+DGI+DLSD+RFAVIIDEAHSSQ G  +D +N AMG      +E
Sbjct  403   NGKKIIITTIQKFPYIVDGIADLSDRRFAVIIDEAHSSQDGHNQDKLNEAMGFV----SE  458

Query  465   DAQDKILQAMNSRKMRGNASYLAFTATPKNSTLEKFGQKQADGTFKPFHLYSMKQAIEEG  524
             D  DK LQ+ ++RKMR+NASY+AFTATPKN+TLEKFGQ+QADGT+ PFHLYSMKQAIEEG
Sbjct  459   DVLDKALQSAKNRKMRSNASYFAFTATPKNTTLEKFGQRQADGTYVPFHLYSMKQAIEEG  518

Query  525   FILDVLANYTTYKSYYEIEKSIAENPEFDTKKAQKKLRAYVERSQHTIDTKAEIMLEHFI  584
             FILDV+ANYTTYKSYYEIEKSI +NPEFD+KKAQK+LRAYVE SQ+TIDTKAEIMLEHFI
Sbjct  519   FILDVIANYTTYKSYYEIEKSIQDNPEFDSKKAQKRLRAYVEASQETIDTKAEIMLEHFI  578

Query  585   PQVVNAkklkgkgkgMVVTQNIEAAIRYYKAIRRILEAQGNSFKVLIAFSGTKEVDGIEY  644
              +VVN+KKLKGKGKGMVVTQNIE+AIRYY+A+   L+  GN+FKV IAFSG+KEVDGIEY
Sbjct  579   KHVVNGKKLKGKGKGMVVTQNIESAIRYYRALTIQLNKMGNPFKVAIAFSGSKEVDGIEY  638

Query  645   TEADINGFAE-----------------tdtkdkfdtdEYRLLVVANKYLTGFDQPKLCAM  687
             TEADINGF+E                 +      D D YRLLVVANKYLTGFDQPKLCAM
Sbjct  639   TEADINGFPEGDTKDYFDVNYKRKEPDSPIPKHVDQDAYRLLVVANKYLTGFDQPKLCAM  698

Query  688   YVDKKLASVLCVQALSRLNRSAPKWGKKTEDLFVLDFFNSAEDIQAAFDPFYTATSLSQA  747
             YVDKKLASVLCVQALSRLNRSAPK GKKTEDLFVLDFFNS +DI++AFDPFYT+T+LS+A
Sbjct  699   YVDKKLASVLCVQALSRLNRSAPKYGKKTEDLFVLDFFNSVDDIKTAFDPFYTSTTLSEA  758

Query  748   TDINVLHELKDALDEVGVYEWYEVENFVARFFNNEDAQTLSPIIDTAAARFESELELAPE  807
             TD+NVLHELKD +D+ GVYEW+EVE+F  RFF+  +AQ LSPIID AAARF+ ELEL  E
Sbjct  759   TDVNVLHELKDDMDDTGVYEWFEVEEFNKRFFEGREAQDLSPIIDIAAARFNHELELENE  818

Query  808   AKIDFKIKAKQFVKIYGQMASIMPYEMVAWEKLFWFLKFLIPKLKVADPDADAIDELLES  867
              K+DFK+KAKQFVKIYGQ+ASIMPYE+V WEKLFWFLKFLIPKL V DPD +A+D LL+S
Sbjct  819   FKVDFKVKAKQFVKIYGQIASIMPYEVVQWEKLFWFLKFLIPKLSVEDPDKEALDSLLDS  878

Query  868   VDLSSYGLQRVKLNHVIKLNDQETELDPQNPNPRGAHGGEKEADPLDEIIRTFNERWFQG  927
             VDLSSYGLQRVKLNH I L+D ETELDPQNPNPRGA G E E DPLDEII+ FNERWFQG
Sbjct  879   VDLSSYGLQRVKLNHSIELDDSETELDPQNPNPRGAYGPEAEKDPLDEIIKIFNERWFQG  938

Query  928   WSVTPEEQRIRLLSMRDALTKHPDFKSKYLESADPHNQHLAFEKMVKEIMLQKRKDDLDF  987
             WS TPEEQR++++++ +++ +HPDF +KY ++ADPH ++LAFEKM+KEIMLQ+RKD+L++
Sbjct  939   WSATPEEQRVKFVNIAESIRNHPDFEAKYQNNADPHTRELAFEKMLKEIMLQRRKDELEL  998

Query  988   YKLWANDAAFKASLMNSIQRMVD  1010
             YKL A+D+AFKAS  +S+QRMV+
Sbjct  999   YKLFAQDPAFKASWTQSMQRMVG  1021

24) Nhal_0754 in NC_013960


> EU272902|14|G13|167832520|ACA01830.1|Vibrio_cholerae_Amazonia_3509|-|13968..17036|-|VPI2_0013c|type 
I restriction enzyme 
HsdR
Length=1022

 Score = 1168 bits (4428),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 718/1028 (70%), Positives = 876/1028 (86%), Gaps = 30/1028 (2%)

Query  1     MVSQTNEQALEATIEKYLTGTCLEEQKAIREGIREVPFS-PNQGYKLGQAADFNAHYAVD  59
             MVS+TNEQALEA+IEK L+G C EE      ++ E P++  N+ Y +G ++DF+ +YA+D
Sbjct  4     MVSKTNEQALEAAIEKGLAGICKEEL-----ALGEAPLNYNNDLYLIGSPSDFDKQYALD  58

Query  60    TRLFWQFLESAQAEELDKLKKHHP-DWRSKILERFDrlvkkhgllhllkrglSIDDAHFH  118
             TRLFWQFLE +QA EL+KLK+  P DW+ KILERFDR++ +HG+L+LLK+GL +DDA + 
Sbjct  59    TRLFWQFLEDTQASELEKLKRTSPHDWQRKILERFDRMIMRHGVLRLLKKGLDVDDAFLS  118

Query  119   LMFPPPLASSSDKVKENFSANLFSSTRQVRYSLTRTLEEIDLVLFINGLPFATLELKNPW  178
             LM+P+PLASSS+KVK +FSANLFS TRQV YS +  LEEID+VLFING+P+ TLELKNPW
Sbjct  119   LMYPAPLASSSEKVKKDFSANLFSVTRQVCYSNANPLEEIDMVLFINGIPLITLELKNPW  178

Query  179   TGQTARYHGQRQYRLERDITQPLLQFGRCLVHMAVDTDEVYMTTKLAGKSTFFLPFNKGH  238
             TGQ A YHGQ+QYR +RD  QPLL+F+RCLVHMAVDTDEVYMTTKLAGK+TFFLPFNKG 
Sbjct  179   TGQNAVYHGQKQYRDDRDANQPLLNFARCLVHMAVDTDEVYMTTKLAGKNTFFLPFNKGF  238

Query  239   HFGAGNPPNPGGHKSAYLWREVFSKESIANIIQHFVRLDGGSKTSLAKRTLFFPRYHQLD  298
             +FG GNP NP GHK+AYLW+EVF KESIANIIQHF+RLDG+SK  L KRTLFFPRYHQ+D
Sbjct  239   NFGKGNPINPHGHKTAYLWQEVFRKESIANIIQHFIRLDGSSKKQLDKRTLFFPRYHQMD  298

Query  299   VVRKLVAHASERGVGQTYLIQHSAGSGKSHSITWAAYQLIETYPVSAHVRGAKGLDAPLF  358
             VVR+LV H S  GVGQTYLIQHSAGSGKS+SITWAAYQLIETYP+S ++ G++G + PLF
Sbjct  299   VVRRLVDHCSVNGVGQTYLIQHSAGSGKSNSITWAAYQLIETYPISDDLPGSRGKEVPLF  358

Query  359   DSVIVVTDRRLLDKQLRENIREFSEVKNIIAPALRSSDLKQALEQGKKIIITTLQKFPFI  418
             DSVIVVTDRRLLDKQLR+NI+EFSEVKNI+APA++SS+LK ALE+GKKIIITT+QKFP+I
Sbjct  359   DSVIVVTDRRLLDKQLRDNIKEFSEVKNIVAPAFKSSELKSALENGKKIIITTIQKFPYI  418

Query  419   IDGIEDMSDKCFAVIIDEAHGSQDGSAHGKMNQAMGRdaddeddqsdpqdKVLNAMRSRK  478
             +DGI D+SD+ FAVIIDEAH+SQDG  ++K+N+AMG          D  DK L++ ++RK
Sbjct  419   VDGIADLSDRRFAVIIDEAHSSQDGHNQDKLNEAMG------FVSEDVLDKALQSAKNRK  472

Query  479   MRGNASYFAFTATPKNSTLEKFGQQQPDGSFKPFHLYSMKQAIEEGFILDVLANYTTYKS  538
             MR+NASYFAFTATPKN+TLEKFGQ+Q+DG++ PFHLYSMKQAIEEGFILDV+ANYTTYKS
Sbjct  473   MRSNASYFAFTATPKNTTLEKFGQRQADGTYVPFHLYSMKQAIEEGFILDVIANYTTYKS  532

Query  539   YYEIQKSIEDNPLFDTAKAQKKLRAYVERNPQTINAKAEIILEHFIPQVVNAKKLRGRAK  598
             YYEI+KSI+DNP FD+ KAQK+LRAYVE + +TI++KAEI+LEHFI +VVN+KKL+G++K
Sbjct  533   YYEIEKSIQDNPEFDSKKAQKRLRAYVEASQETIDTKAEIMLEHFIKHVVNGKKLKGKGK  592

Query  599   GMVITQNIETAIRYHQAIGCILRDRGNPFKALVAFSGAKEVDGIEYTEAEMNGFPEADTR  658
             GMV+TQNIE+AIRY +A+   L   GNPFK  +AFSG+KEVDGIEYTEA++NGFPE+DT+
Sbjct  593   GMVVTQNIESAIRYYRALTIQLNKMGNPFKVAIAFSGSKEVDGIEYTEADINGFPEGDTK  652

Query  659   DKF-----------------DKDEYRLLVVANKYLTGFDQPKLTAMYVDKKLQGVLAVQA  701
             D F                 D+D YRLLVVANKYLTGFDQPKL AMYVDKKL +VL VQA
Sbjct  653   DYFDVNYKRKEPDSPIPKHVDQDAYRLLVVANKYLTGFDQPKLCAMYVDKKLASVLCVQA  712

Query  702   LSRLNRAAPQWGKKTEDLFVLDFFNTVEDIKAAFDPFYTATSLSQATDVNVLHELKDALG  761
             LSRLNR+AP+ GKKTEDLFVLDFFN+V+DIK+AFDPFYT+T+LS+ATDVNVLHELKD ++
Sbjct  713   LSRLNRSAPKYGKKTEDLFVLDFFNSVDDIKTAFDPFYTSTTLSEATDVNVLHELKDDMD  772

Query  762   DVGVYEWREVEAFVGLYFDNADAQQLSPLMDTAAARFNQELGLEDEEKADFKIKAKQFVK  821
             D GVYEW EVE F   +F+  +AQ+LSP++D AAARFN+EL LE+E K DFK+KAKQFVK
Sbjct  773   DTGVYEWFEVEEFNKRFFEGREAQDLSPIIDIAAARFNHELELENEFKVDFKVKAKQFVK  832

Query  822   IYGQMASIMPYEVVAWEKLFWFLKFLIPKLVVKSKDADEIDALLDSVDLSSYGLERVKLN  881
             IYGQ+ASIMPYEVV WEKLFWFLKFLIPKL V   D + +D+LLDSVDLSSYGL+RVKLN
Sbjct  833   IYGQIASIMPYEVVQWEKLFWFLKFLIPKLSVEDPDKEALDSLLDSVDLSSYGLQRVKLN  892

Query  882   QAIGLDESETEVDPTNPNPRGVHGGGEEQDPLDEIIQSFNERWFQGWEATPEEQRVKFLS  941
             ++I LD+SETE+DP NPNPRG  G   E+DPLDEII+ FNERWFQGW ATPEEQRVKF++
Sbjct  893   HSIELDDSETELDPQNPNPRGAYGPEAEKDPLDEIIKIFNERWFQGWSATPEEQRVKFVN  952

Query  942   IIKSIQAHPDFEAKYKHNQDADNRTLAFEKIFEEVMLERRKMDLDLYRLLASDPAFKSSL  1001
             I  SI+ HPDFEAKY++N D++ R LAFEK++ E+ML+RRK +L+LY+L+A DPAFK+S 
Sbjct  953   IAESIRNHPDFEAKYQNNADPHTRELAFEKMLKEIMLQRRKDELELYKLFAQDPAFKASW  1012

Query  1002  QQSLRHLL  1009
              QS+++++
Sbjct  1013  TQSMQRMV  1020

25) CGSHiGG_03090 in NC_009567


> EU272902|14|G13|167832520|ACA01830.1|Vibrio_cholerae_Amazonia_3509|-|13968..17036|-|VPI2_0013c|type 
I restriction enzyme 
HsdR
Length=1022

 Score = 1147 bits (4348),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 692/1026 (68%), Positives = 870/1026 (85%), Gaps = 29/1026 (2%)

Query  1     MVSGTKEKDLEIAIEKALTGTWRENMENKLGEPKAEYLPRHHGFKLAFSQDFDAKFAIDL  60
             MVS T+E+ LE AIEK+L+G  +E++   LGE+  +Y   ++ + ++ + DFD ++A+D 
Sbjct  4     MVSKTNEQALEAAIEKGLAGICKEELA--LGEAPLNY--NNDLYLIGSPSDFDKQYALDT  59

Query  61    RLFWQFLQTGQKAELVRFQQLNPNDWQRKILERLDRQIKKYGVLQLLKKGLDIDSAHFDL  120
             RLFWQFL+  Q +EL ++++ +P+DWQRKILER+DR I + GVL+LLKKGLD+D A + L
Sbjct  60    RLFWQFLEDTQASELEKLKRTSPHDWQRKILERFDRMIMRHGVLRLLKKGLDVDDAFLSL  119

Query  121   LYPVPLASSGEKVKQRFEQNLFSCMRQVPYSASSN-ETVDMVLFVNGLPIITLELKNHWT  179
             +YP PLASS+EKVK+ F  NLFS  RQV YS ++  E +DMVLF+NG+P+ITLELKN WT
Sbjct  120   MYPAPLASSSEKVKKDFSANLFSVTRQVCYSNANPLEEIDMVLFINGIPLITLELKNPWT  179

Query  180   GQTAI-DAQKQYRN-RDLSQTLFHFGRCLAHFALDTEEAYMTTKLAGSDTFFLPFNLGNN  237
             GQ A+ ++QKQYR+ RD +Q L++F+RCL H A+DT+E YMTTKLAG +TFFLPFN G N
Sbjct  180   GQNAVYHGQKQYRDDRDANQPLLNFARCLVHMAVDTDEVYMTTKLAGKNTFFLPFNKGFN  239

Query  238   YGKGNLANPNGHRTAYLWQEVFSKASLANIIQHFMRLDGSTKDPLEKRSLFFPRYHQLEV  297
             +GKGN  NP+GH+TAYLWQEVF K S+ANIIQHF+RLDGS+K  L+KR+LFFPRYHQ++V
Sbjct  240   FGKGNPINPHGHKTAYLWQEVFRKESIANIIQHFIRLDGSSKKQLDKRTLFFPRYHQMDV  299

Query  298   VRRLIADVSEQGVGKRYLIQHSAGSGKSNSITWLAYQLIEAYPRNEKAANGREADRPIFD  357
             VRRL+ + S +GVG+ YLIQHSAGSGKSNSITW AYQLIE+YP ++  + +R  + P+FD
Sbjct  300   VRRLVDHCSVNGVGQTYLIQHSAGSGKSNSITWAAYQLIETYPISDDLPGSRGKEVPLFD  359

Query  358   SVIVVTDRRLLDKQLRDNIKDFSEVKNIVAPALSSAELRQSLEQGkkiiittiQKFPFIV  417
             SVIVVTDRRLLDKQLRDNIK+FSEVKNIVAPA+ S+EL+ +LE+GKKIIITTIQKFP+IV
Sbjct  360   SVIVVTDRRLLDKQLRDNIKEFSEVKNIVAPAFKSSELKSALENGKKIIITTIQKFPYIV  419

Query  418   DGIADLGDKQFAVIIDEAHSSQSGSAHDNMNRAIGKTEDLDAEDVQDLILQTMQSRKMRG  477
             DGIADL+D++FAVIIDEAHSSQ G  +D++N A+G    + +EDV D  LQ+ ++RKMR+
Sbjct  420   DGIADLSDRRFAVIIDEAHSSQDGHNQDKLNEAMG----FVSEDVLDKALQSAKNRKMRS  475

Query  478   NASYFAFTATPKNSTLEKFGEKQADGKFKPFHLYSMKQAIEEGFILDVIANYTTYKSFYE  537
             NASYFAFTATPKN+TLEKFG++QADG + PFHLYSMKQAIEEGFILDVIANYTTYKS+YE
Sbjct  476   NASYFAFTATPKNTTLEKFGQRQADGTYVPFHLYSMKQAIEEGFILDVIANYTTYKSYYE  535

Query  538   ITKSIEDNPEFDSKKAQGRLKAYVECSQQTIDTKAEIMLDHFIQQILNRKKLKGKAKGMV  597
             I KSI+DNPEFDSKKAQ RL+AYVE SQ+TIDTKAEIML+HFI++++N KKLKGK+KGMV
Sbjct  536   IEKSIQDNPEFDSKKAQKRLRAYVEASQETIDTKAEIMLEHFIKHVVNGKKLKGKGKGMV  595

Query  598   VTQNIETAIRYFQALNRLLAERGNPFKIAIAFSGSKVVDGVEYTEAEMNGFAESETKEYF  657
             VTQNIE+AIRY++AL   L   GNPFK+AIAFSGSK VDG+EYTEA++NGF+E++TK+YF
Sbjct  596   VTQNIESAIRYYRALTIQLNKMGNPFKVAIAFSGSKEVDGIEYTEADINGFPEGDTKDYF  655

Query  658   -----------------DQDEYRLLVVANKYLTGFDQPKLCAMYVDKKLSGVLCVQALSR  700
                              DQD YRLLVVANKYLTGFDQPKLCAMYVDKKL++VLCVQALSR
Sbjct  656   DVNYKRKEPDSPIPKHVDQDAYRLLVVANKYLTGFDQPKLCAMYVDKKLASVLCVQALSR  715

Query  701   LNRSANKLGKRTEDLFVLDFFNSVEDIQQAFEPFYTSTSLSQATDVNVLHDLKDQLDETG  760
             LNRSA K GK+TEDLFVLDFFNSV+DI+ AF+PFYTST+LS+ATDVNVLH+LKD++D+TG
Sbjct  716   LNRSAPKYGKKTEDLFVLDFFNSVDDIKTAFDPFYTSTTLSEATDVNVLHELKDDMDDTG  775

Query  761   VYEQAEVNDFTEGYFANKDAQQLSSIIDVAVQRFDHELALEPTQKVDFKIKAKQFLKIYG  820
             VYE  EV++F   +F  ++AQ+LS+IID+A  RF+HEL LE   KVDFK+KAKQF+KIYG
Sbjct  776   VYEWFEVEEFNKRFFEGREAQDLSPIIDIAAARFNHELELENEFKVDFKVKAKQFVKIYG  835

Query  821   QMASIINFENIAWEKLYWFLKFLVPKLKVQDP-MDEFDEILDAVDLSSYGLARTKLNYSI  879
             Q+ASI+ +E + WEKL+WFLKFL+PKL V+DP  + +D +LD+VDLSSYGL R KLN SI
Sbjct  836   QIASIMPYEVVQWEKLFWFLKFLIPKLSVEDPDKEALDSLLDSVDLSSYGLQRVKLNHSI  895

Query  880   KLDDEETELDPQNPNPRGTHGEDKEKDPIDEIIRVFNERWFQDWSATPDEQRVKFINITE  939
              LDD ETELDPQNPNPRG+ G + EKDP+DEII++FNERWFQ+WSATP+EQRVKF+NI+E
Sbjct  896   ELDDSETELDPQNPNPRGAYGPEAEKDPLDEIIKIFNERWFQGWSATPEEQRVKFVNIAE  955

Query  940   RIRSHKDFEQKYQNNPDIHTRELAFQAILRDVMSERHRDELELYKLFAKDAAFRTAWTQS  999
              IR+H DFE KYQNN+D HTRELAF+ +L+++M +R++DELELYKLFA+D+AF+++WTQS
Sbjct  956   SIRNHPDFEAKYQNNADPHTRELAFEKMLKEIMLQRRKDELELYKLFAQDPAFKASWTQS  1015

Query  1000  LQRALA  1005
             +QR ++
Sbjct  1016  MQRMVG  1021

26) PSPPH_0104 in NC_005773


> EU272902|14|G13|167832520|ACA01830.1|Vibrio_cholerae_Amazonia_3509|-|13968..17036|-|VPI2_0013c|type 
I restriction enzyme 
HsdR
Length=1022

 Score = 1138 bits (4315),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 705/1023 (69%), Positives = 862/1023 (85%), Gaps = 23/1023 (2%)

Query  1     MVSKTNEQALEASIEKYLTGNCLEEQATIRDGVKELPFDPNHGYQLGRVQDFNARYAVDT  60
             MVSKTNEQALEA+IEK L+G C EE A    G   L ++ +  Y +G   DF+ +YA+DT
Sbjct  4     MVSKTNEQALEAAIEKGLAGICKEELAL---GEAPLNYNNDL-YLIGSPSDFDKQYALDT  59

Query  61    RCLWRFLHDSQGDELERLKQRY-DDWDLRILERFDRLAKKYGVLHLFKRGLAIDDVHLNL  119
             R +W+FL+D+Q+ ELE+LK+   +DW+ +ILERFDR+  + GVL+L+K+GL +DD  L+L
Sbjct  60    RLFWQFLEDTQASELEKLKRTSPHDWQRKILERFDRMIMRHGVLRLLKKGLDVDDAFLSL  119

Query  120   MYPAPLASSSGRVKRQFAANIFSSTRQVRYSLSNPLEEIDLVLFVNGLPVATLELKNPWT  179
             MYPAPLASSS +VK++F+AN+FS TRQV YS +NPLEEID+VLF+NG+P+ TLELKNPWT
Sbjct  120   MYPAPLASSSEKVKKDFSANLFSVTRQVCYSNANPLEEIDMVLFINGIPLITLELKNPWT  179

Query  180   GQTARYHGQKQYRQGRDSSQPLLQFGRCLVHMTVDTDEVYMTTKLAGTATFFLPFNKGHN  239
             GQ A YHGQKQYR++RD++QPLL+F+RCLVHM+VDTDEVYMTTKLAG  TFFLPFNKG N
Sbjct  180   GQNAVYHGQKQYRDDRDANQPLLNFARCLVHMAVDTDEVYMTTKLAGKNTFFLPFNKGFN  239

Query  240   YGAGNPPNLAGHKSAYLWREIFSRESVANIIQHFVRLDGSSKTPLAKRTLFFPRYHQLDV  299
             +G GNP N  GHK+AYLW+E+F +ES+ANIIQHF+RLDGSSK  L KRTLFFPRYHQ+DV
Sbjct  240   FGKGNPINPHGHKTAYLWQEVFRKESIANIIQHFIRLDGSSKKQLDKRTLFFPRYHQMDV  299

Query  300   VRRLVAHASQQGVGQRYLIQHSAGSGKSNSITWAAYQLIETYPASLNVAGARGLDVPLFD  359
             VRRLV H S +GVGQ YLIQHSAGSGKSNSITWAAYQLIETYP S +++G+RG +VPLFD
Sbjct  300   VRRLVDHCSVNGVGQTYLIQHSAGSGKSNSITWAAYQLIETYPISDDLPGSRGKEVPLFD  359

Query  360   SVIVVTDRRLLDKQLRENLREFSEVKNIIAPALKSSDLKQALEQGkkiiittiQKFPWIV  419
             SVIVVTDRRLLDKQLR+N++EFSEVKNI+APA+KSS+LK ALE+GKKIIITTIQKFP IV
Sbjct  360   SVIVVTDRRLLDKQLRDNIKEFSEVKNIVAPAFKSSELKSALENGKKIIITTIQKFPYIV  419

Query  420   DGIDDMAGKRFAVIIDEAHSSQDGSSHGTMNSVMGGDDQDDTQEKILSAIKNSKMRGNAS  479
             DGI D++++RFAVIIDEAHSSQDG +++ +N  MG    +D  +K L + KN KMR+NAS
Sbjct  420   DGIADLSDRRFAVIIDEAHSSQDGHNQDKLNEAMGFVS-EDVLDKALQSAKNRKMRSNAS  478

Query  480   YFAFTATPKNSTLEKFGEQQADGRFEPFHLYSMKQAIEEGFILDVLANYTTYRSYYEIQK  539
             YFAFTATPKN+TLEKFG++QADG + PFHLYSMKQAIEEGFILDV+ANYTTY+SYYEI+K
Sbjct  479   YFAFTATPKNTTLEKFGQRQADGTYVPFHLYSMKQAIEEGFILDVIANYTTYKSYYEIEK  538

Query  540   SIEDDPLFDKLKAQKKLRAYVERDQQTIDVKAEVMLDHFIDQVVTPKKLKGQGKGMVITQ  599
             SI+D+P FD  KAQK+LRAYVE  Q+TID KAE+ML+HFI +VV  KKLKG+GKGMV+TQ
Sbjct  539   SIQDNPEFDSKKAQKRLRAYVEASQETIDTKAEIMLEHFIKHVVNGKKLKGKGKGMVVTQ  598

Query  600   NIESAIRYHKAISRLLAARGNPFKALIAFSGDKLVDGIEYSEAGINGSAEADTRDKFDT-  658
             NIESAIRY +A++  L   GNPFK  IAFSG K VDGIEY+EA+ING +E+DT+D FD  
Sbjct  599   NIESAIRYYRALTIQLNKMGNPFKVAIAFSGSKEVDGIEYTEADINGFPEGDTKDYFDVN  658

Query  659   ----------------DEYRLLVVANKYLTGFDQPKLCAMYVDKKLQYVLAVQALSRLNR  702
                             D YRLLVVANKYLTGFDQPKLCAMYVDKKL  VL VQALSRLNR
Sbjct  659   YKRKEPDSPIPKHVDQDAYRLLVVANKYLTGFDQPKLCAMYVDKKLASVLCVQALSRLNR  718

Query  703   AAPKWGKKTEDLFVLDFFNLVEDIKASFDPFYTATSLSRATDINVLHELKDQLDELGVYE  762
             +APK GKKTEDLFVLDFFN V+DIK++FDPFYT+T+LS ATD+NVLHELKD++D+ GVYE
Sbjct  719   SAPKYGKKTEDLFVLDFFNSVDDIKTAFDPFYTSTTLSEATDVNVLHELKDDMDDTGVYE  778

Query  763   WPEVEAFAAQYFDNVDAEQLAVLIDIAverfeveleledeAKVDFKIKAKQFVKIYGQMA  822
             W EVE F  ++F+  +A++L+ +IDIA  RF+ ELELE+E KVDFK+KAKQFVKIYGQ+A
Sbjct  779   WFEVEEFNKRFFEGREAQDLSPIIDIAAARFNHELELENEFKVDFKVKAKQFVKIYGQIA  838

Query  823   SIMPYEIVAWEKLFWFLKFLIPKLKVQDKDADEIDALLNSVDLSSYGLERVKLNHSIALD  882
             SIMPYE+V WEKLFWFLKFLIPKL V+D D + +D+LL+SVDLSSYGL+RVKLNHSI LD
Sbjct  839   SIMPYEVVQWEKLFWFLKFLIPKLSVEDPDKEALDSLLDSVDLSSYGLQRVKLNHSIELD  898

Query  883   DADTELDPANPNPRGVHGGEQEKDPLDQIIQSFNERWFQGWGVTTEEKRVKFLSILQGIQ  942
             D++TELDP NPNPRG  G E EKDPLD+II+ FNERWFQGW+ T EE+RVKF++I ++I+
Sbjct  899   DSETELDPQNPNPRGAYGPEAEKDPLDEIIKIFNERWFQGWSATPEEQRVKFVNIAESIR  958

Query  943   EHPDFEPKYQKSQDEDHRALAFEKMFEEVMLMRRRQDLELYRLVASDAVLKSSLQQSMRG  1002
             +HPDFE+KYQ++ D + R LAFEKM+ E+ML RR+++LELY+L A D+ +K+S  QSM+ 
Sbjct  959   NHPDFEAKYQNNADPHTRELAFEKMLKEIMLQRRKDELELYKLFAQDPAFKASWTQSMQR  1018

Query  1003  MLD  1005
             M++
Sbjct  1019  MVG  1021

27) hsdR2 in NC_017452


> EU272902|14|G13|167832520|ACA01830.1|Vibrio_cholerae_Amazonia_3509|-|13968..17036|-|VPI2_0013c|type 
I restriction enzyme 
HsdR
Length=1022

 Score = 1138 bits (4317),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 686/1027 (67%), Positives = 871/1027 (85%), Gaps = 30/1027 (2%)

Query  1     MVSGTKEKDLEIAIEKALTGTWRENMENKLGEPKAEYHLPRHHGFELAFSQDFDAQFAID  60
             MVS T+E+ LE AIEK+L+G  +E++   LGE+  +Y+   ++ + ++ + DFD Q+A+D
Sbjct  4     MVSKTNEQALEAAIEKGLAGICKEELA--LGEAPLNYN---NDLYLIGSPSDFDKQYALD  58

Query  61    TRLFWQFLQTSQKAELARFQQLNPNDWQRKILERLDRQIKKNGVLHLLKKGLDIDSAHFD  120
             TRLFWQFL+ +Q +EL ++++ +P+DWQRKILER+DR I ++GVL+LLKKGLD+D A + 
Sbjct  59    TRLFWQFLEDTQASELEKLKRTSPHDWQRKILERFDRMIMRHGVLRLLKKGLDVDDAFLS  118

Query  121   LLYPVPLASSGEKVKQRFEQNLFSCMRQVPYSASSN-ETVDMVLFVNGLPIITLELKNHW  179
             L+YP PLASS+EKVK+ F  NLFS  RQV YS ++  E +DMVLF+NG+P+ITLELKN W
Sbjct  119   LMYPAPLASSSEKVKKDFSANLFSVTRQVCYSNANPLEEIDMVLFINGIPLITLELKNPW  178

Query  180   TGQTAI-DAQKQYRN-RDLSQTLFHFGRCLAYFALDTEEAYMTTKLAGPATFFLPFNLGN  237
             TGQ A+ ++QKQYR+ RD +Q L++F+RCL   A+DT+E YMTTKLAG  TFFLPFN G 
Sbjct  179   TGQNAVYHGQKQYRDDRDANQPLLNFARCLVHMAVDTDEVYMTTKLAGKNTFFLPFNKGF  238

Query  238   NCGKGNPLNPNGHRTSYLWQEVFSKASLANIIQHFMRLDGSTKDPLEKRSLFFPRYHQLE  297
             N GKGNP+NP+GH+T+YLWQEVF K S+ANIIQHF+RLDGS+K  L+KR+LFFPRYHQ++
Sbjct  239   NFGKGNPINPHGHKTAYLWQEVFRKESIANIIQHFIRLDGSSKKQLDKRTLFFPRYHQMD  298

Query  298   VVRRLIADVSEQGVGKRYLIQHSAGSGKSNSITWLAYQLIEAYPCNEKAANGREADRPIF  357
             VVRRL+ + S +GVG+ YLIQHSAGSGKSNSITW AYQLIE+YP ++  + +R  + P+F
Sbjct  299   VVRRLVDHCSVNGVGQTYLIQHSAGSGKSNSITWAAYQLIETYPISDDLPGSRGKEVPLF  358

Query  358   DSVIVVTDRRLLDKQLRDNIKDFSEVKNIVAPALSSAELRQSLEQGkkiiittiQKFPFI  417
             DSVIVVTDRRLLDKQLRDNIK+FSEVKNIVAPA+ S+EL+ +LE+GKKIIITTIQKFP+I
Sbjct  359   DSVIVVTDRRLLDKQLRDNIKEFSEVKNIVAPAFKSSELKSALENGKKIIITTIQKFPYI  418

Query  418   VDGIADLGDKQFAVIIDEAHSSQSGSAHDNMNRAIGKTEDLDAEDVQDLILQAMQSRKMR  477
             VDGIADL+D++FAVIIDEAHSSQ G  +D++N A+G    + +EDV D  LQ+ ++RKMR
Sbjct  419   VDGIADLSDRRFAVIIDEAHSSQDGHNQDKLNEAMG----FVSEDVLDKALQSAKNRKMR  474

Query  478   GNASYFAFTATPKNSTLEKFGEKQADGKFKPFHLYSMKQAIEEGFILDVIANYTTYKSFY  537
             +NASYFAFTATPKN+TLEKFG++QADG + PFHLYSMKQAIEEGFILDVIANYTTYKS+Y
Sbjct  475   SNASYFAFTATPKNTTLEKFGQRQADGTYVPFHLYSMKQAIEEGFILDVIANYTTYKSYY  534

Query  538   EITKSIEDNPEFDSKKAQGRLKAYVERSQQTIDTKAEIMLDHFIRQIFSRKKLKGKAKGM  597
             EI KSI+DNPEFDSKKAQ RL+AYVE SQ+TIDTKAEIML+HFI+++ + KKLKGK+KGM
Sbjct  535   EIEKSIQDNPEFDSKKAQKRLRAYVEASQETIDTKAEIMLEHFIKHVVNGKKLKGKGKGM  594

Query  598   VVTQNIETAIRYFQALKHLLAGRGNPFKIAIAFSGSKVVDGVEYTEAEMNGFAESETKEY  657
             VVTQNIE+AIRY++AL   L   GNPFK+AIAFSGSK VDG+EYTEA++NGF+E++TK+Y
Sbjct  595   VVTQNIESAIRYYRALTIQLNKMGNPFKVAIAFSGSKEVDGIEYTEADINGFPEGDTKDY  654

Query  658   F-----------------DQDEYRLLVVANKYLTGFDQPKLCAMYVDKKLSGVLCVQALS  700
             F                 DQD YRLLVVANKYLTGFDQPKLCAMYVDKKL++VLCVQALS
Sbjct  655   FDVNYKRKEPDSPIPKHVDQDAYRLLVVANKYLTGFDQPKLCAMYVDKKLASVLCVQALS  714

Query  701   RLNRSANKLSKRTEDLFVLDFFNSVEDIQQAFEPFYTSTSLSQATDVNVLHDLKDRLDET  760
             RLNRSA K +K+TEDLFVLDFFNSV+DI+ AF+PFYTST+LS+ATDVNVLH+LKD +D+T
Sbjct  715   RLNRSAPKYGKKTEDLFVLDFFNSVDDIKTAFDPFYTSTTLSEATDVNVLHELKDDMDDT  774

Query  761   GVYEQAEVNDFTEGYFANKDAQQLSSMIDVAVQRFDDELDLDRNEKVDFKIKAKQFLKIY  820
             GVYE  EV++F   +F  ++AQ+LS++ID+A  RF++EL+L+ + KVDFK+KAKQF+KIY
Sbjct  775   GVYEWFEVEEFNKRFFEGREAQDLSPIIDIAAARFNHELELENEFKVDFKVKAKQFVKIY  834

Query  821   GQTASIINFENIAWEKLYWFLKFLVPKLKVQDP-MDEFDEILDAVDLSSYGLARTKLNYS  879
             GQ ASI+ +E + WEKL+WFLKFL+PKL V+DP  + +D +LD+VDLSSYGL R KLN S
Sbjct  835   GQIASIMPYEVVQWEKLFWFLKFLIPKLSVEDPDKEALDSLLDSVDLSSYGLQRVKLNHS  894

Query  880   IKLDDEETGLDPQNPNPRGTHSEDKEKDPIDEIIRVFNERWFQDWSATPDEQRVKFINIT  939
             I LDD ET LDPQNPNPRG+ + + EKDP+DEII++FNERWFQ+WSATP+EQRVKF+NI+
Sbjct  895   IELDDSETELDPQNPNPRGAYGPEAEKDPLDEIIKIFNERWFQGWSATPEEQRVKFVNIA  954

Query  940   ERIRSHKDFEQKYQNNPDIHTRELAFQAILRDVMSERHRDELELYKLFAKDAAFRTAWTQ  999
             E IR+H DFE KYQNN+D HTRELAF+ +L+++M +R++DELELYKLFA+D+AF+++WTQ
Sbjct  955   ESIRNHPDFEAKYQNNADPHTRELAFEKMLKEIMLQRRKDELELYKLFAQDPAFKASWTQ  1014

Query  1000  SLQRALA  1006
             S+QR ++
Sbjct  1015  SMQRMVG  1021

28) CGSHiEE_02750 in NC_009566


> EU272902|14|G13|167832520|ACA01830.1|Vibrio_cholerae_Amazonia_3509|-|13968..17036|-|VPI2_0013c|type 
I restriction enzyme 
HsdR
Length=1022

 Score = 1131 bits (4287),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 680/1018 (67%), Positives = 864/1018 (85%), Gaps = 30/1018 (2%)

Query  1     MEIAIEKALTGTWRENMENKLGEPKAEYHLPRHHGFELAFSQDFDAQFAIDTRLFWQFLQ  60
             +E AIEK+L+G  +E++   LGE+  +Y+   ++ + ++ + DFD Q+A+DTRLFWQFL+
Sbjct  13    LEAAIEKGLAGICKEELA--LGEAPLNYN---NDLYLIGSPSDFDKQYALDTRLFWQFLE  67

Query  61    TSQKAELARFQQLNPNDWQRKILERLDRQIKKNGVLHLLKKGLDIDSAHFDLLYPVPLAS  120
              +Q +EL ++++ +P+DWQRKILER+DR I ++GVL+LLKKGLD+D A + L+YP PLAS
Sbjct  68    DTQASELEKLKRTSPHDWQRKILERFDRMIMRHGVLRLLKKGLDVDDAFLSLMYPAPLAS  127

Query  121   SGEKVKQRFEQNLFSCMRQVPYSASSN-ETVDMVLFVNGLPIITLELKNHWTGQTAI-DA  178
             S+EKVK+ F  NLFS  RQV YS ++  E +DMVLF+NG+P+ITLELKN WTGQ A+ ++
Sbjct  128   SSEKVKKDFSANLFSVTRQVCYSNANPLEEIDMVLFINGIPLITLELKNPWTGQNAVYHG  187

Query  179   QKQYRN-RDLSQTLFHFGRCLAYFALDTEEAYMTTKLAGPATFFLPFNLGNNCGKGNPLN  237
             QKQYR+ RD +Q L++F+RCL   A+DT+E YMTTKLAG  TFFLPFN G N GKGNP+N
Sbjct  188   QKQYRDDRDANQPLLNFARCLVHMAVDTDEVYMTTKLAGKNTFFLPFNKGFNFGKGNPIN  247

Query  238   PNGHRTSYLWQEVFSKASLANIIQHFMRLDGSTKDPLEKRSLFFPRYHQLEVVRRLIADV  297
             P+GH+T+YLWQEVF K S+ANIIQHF+RLDGS+K  L+KR+LFFPRYHQ++VVRRL+ + 
Sbjct  248   PHGHKTAYLWQEVFRKESIANIIQHFIRLDGSSKKQLDKRTLFFPRYHQMDVVRRLVDHC  307

Query  298   SEQGVGKRYLIQHSAGSGKSNSITWLAYQLIEAYPCNEKAANGREADRPIFDSVIVVTDR  357
             S +GVG+ YLIQHSAGSGKSNSITW AYQLIE+YP ++  + +R  + P+FDSVIVVTDR
Sbjct  308   SVNGVGQTYLIQHSAGSGKSNSITWAAYQLIETYPISDDLPGSRGKEVPLFDSVIVVTDR  367

Query  358   RLLDKQLRDNIKDFSEVKNIVAPALSSAELRQSLEQGkkiiittiQKFPFIVDGIADLGD  417
             RLLDKQLRDNIK+FSEVKNIVAPA+ S+EL+ +LE+GKKIIITTIQKFP+IVDGIADL+D
Sbjct  368   RLLDKQLRDNIKEFSEVKNIVAPAFKSSELKSALENGKKIIITTIQKFPYIVDGIADLSD  427

Query  418   KQFAVIIDEAHSSQSGSAHDNMNRAIGKTEDLDAEDVQDLILQAMQSRKMRGNASYFAFT  477
             ++FAVIIDEAHSSQ G  +D++N A+G    + +EDV D  LQ+ ++RKMR+NASYFAFT
Sbjct  428   RRFAVIIDEAHSSQDGHNQDKLNEAMG----FVSEDVLDKALQSAKNRKMRSNASYFAFT  483

Query  478   ATPKNSTLEKFGEKQADGKFKPFHLYSMKQAIEEGFILDVIANYTTYKSFYEITKSIEDN  537
             ATPKN+TLEKFG++QADG + PFHLYSMKQAIEEGFILDVIANYTTYKS+YEI KSI+DN
Sbjct  484   ATPKNTTLEKFGQRQADGTYVPFHLYSMKQAIEEGFILDVIANYTTYKSYYEIEKSIQDN  543

Query  538   PEFDSKKAQGRLKAYVERSQQTIDTKAEIMLDHFIRQIFSRKKLKGKAKGMVVTQNIETA  597
             PEFDSKKAQ RL+AYVE SQ+TIDTKAEIML+HFI+++ + KKLKGK+KGMVVTQNIE+A
Sbjct  544   PEFDSKKAQKRLRAYVEASQETIDTKAEIMLEHFIKHVVNGKKLKGKGKGMVVTQNIESA  603

Query  598   IRYFQALKHLLAGRGNPFKIAIAFSGSKVVDGVEYTEAEMNGFAESETKEYF--------  649
             IRY++AL   L   GNPFK+AIAFSGSK VDG+EYTEA++NGF+E++TK+YF        
Sbjct  604   IRYYRALTIQLNKMGNPFKVAIAFSGSKEVDGIEYTEADINGFPEGDTKDYFDVNYKRKE  663

Query  650   ---------DQDEYRLLVVANKYLTGFDQPKLCAMYVDKKLSGVLCVQALSRLNRSANKL  700
                      DQD YRLLVVANKYLTGFDQPKLCAMYVDKKL++VLCVQALSRLNRSA K 
Sbjct  664   PDSPIPKHVDQDAYRLLVVANKYLTGFDQPKLCAMYVDKKLASVLCVQALSRLNRSAPKY  723

Query  701   SKRTEDLFVLDFFNSVEDIQQAFEPFYTSTSLSQATDVNVLHDLKDRLDETGVYEQAEVN  760
             +K+TEDLFVLDFFNSV+DI+ AF+PFYTST+LS+ATDVNVLH+LKD +D+TGVYE  EV+
Sbjct  724   GKKTEDLFVLDFFNSVDDIKTAFDPFYTSTTLSEATDVNVLHELKDDMDDTGVYEWFEVE  783

Query  761   DFTEGYFANKDAQQLSSMIDVAVQRFDDELDLDRNEKVDFKIKAKQFLKIYGQTASIINF  820
             +F   +F  ++AQ+LS++ID+A  RF++EL+L+ + KVDFK+KAKQF+KIYGQ ASI+ +
Sbjct  784   EFNKRFFEGREAQDLSPIIDIAAARFNHELELENEFKVDFKVKAKQFVKIYGQIASIMPY  843

Query  821   ENIAWEKLYWFLKFLVPKLKVQDP-MDEFDEILDAVDLSSYGLARTKLNYSIKLDDEETG  879
             E + WEKL+WFLKFL+PKL V+DP  + +D +LD+VDLSSYGL R KLN SI LDD ET 
Sbjct  844   EVVQWEKLFWFLKFLIPKLSVEDPDKEALDSLLDSVDLSSYGLQRVKLNHSIELDDSETE  903

Query  880   LDPQNPNPRGTHSEDKEKDPIDEIIRVFNERWFQDWSATPDEQRVKFINITERIRSHKDF  939
             LDPQNPNPRG+ + + EKDP+DEII++FNERWFQ+WSATP+EQRVKF+NI+E IR+H DF
Sbjct  904   LDPQNPNPRGAYGPEAEKDPLDEIIKIFNERWFQGWSATPEEQRVKFVNIAESIRNHPDF  963

Query  940   EQKYQNNPDIHTRELAFQAILRDVMSERHRDELELYKLFAKDAAFRTAWTQSLQRALA  997
             E KYQNN+D HTRELAF+ +L+++M +R++DELELYKLFA+D+AF+++WTQS+QR ++
Sbjct  964   EAKYQNNADPHTRELAFEKMLKEIMLQRRKDELELYKLFAQDPAFKASWTQSMQRMVG  1021

29) PBPRA0886 in NC_006370


> EU272902|14|G13|167832520|ACA01830.1|Vibrio_cholerae_Amazonia_3509|-|13968..17036|-|VPI2_0013c|type 
I restriction enzyme 
HsdR
Length=1022

 Score = 1129 bits (4281),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 730/1023 (72%), Positives = 883/1023 (87%), Gaps = 22/1023 (2%)

Query  10    MVSQTNEMALEAAIEKALVGITTEERKQGIAEPFAVYSKDHAYSIGFPSDFDAKYAIDKT  69
             MVS+TNE ALEAAIEK+L GI  EE   +++E+   Y++D  Y IG PSDFD +YA+D  
Sbjct  4     MVSKTNEQALEAAIEKGLAGICKEE--LALGEAPLNYNND-LYLIGSPSDFDKQYALDTR  60

Query  70    YFWQFLEDTQPTELEKLQSNSPNDWQQKVLERFDRLIRkhgvlhllkkglAVDDAHLMLM  129
              FWQFLEDTQ++ELEKL+  SP+DWQ+K+LERFDR+I +HGVL+LLKKGL VDDA L LM
Sbjct  61    LFWQFLEDTQASELEKLKRTSPHDWQRKILERFDRMIMRHGVLRLLKKGLDVDDAFLSLM  120

Query  130   YPAPLASSSESVTKNFNANIFSVTRQVRYSQANPLQEIDMVIFINGIALVTLELKNHWTG  189
             YPAPLASSSE V K+F+AN+FSVTRQV YS+ANPL+EIDMV+FINGI+L+TLELKN WTG
Sbjct  121   YPAPLASSSEKVKKDFSANLFSVTRQVCYSNANPLEEIDMVLFINGIPLITLELKNPWTG  180

Query  190   QTARYHGQKQYCNDRDQTQPLLNFARCLVHMAVDTEEVYMTTKLAGKKTFFLPFnkgnnl  249
             Q A YHGQKQY +DRD  QPLLNFARCLVHMAVDT+EVYMTTKLAGK+TFFLPFNKG N+
Sbjct  181   QNAVYHGQKQYRDDRDANQPLLNFARCLVHMAVDTDEVYMTTKLAGKNTFFLPFNKGFNF  240

Query  250   gkgnppnangHKTAYLWQEVFSRESLANIIQHFVRLDGTSKDRLEKRTLFFPRYQQMDVV  309
             GKGNP N++GHKTAYLWQEVF +ES+ANIIQHF+RLDG+SK +L+KRTLFFPRY+QMDVV
Sbjct  241   GKGNPINPHGHKTAYLWQEVFRKESIANIIQHFIRLDGSSKKQLDKRTLFFPRYHQMDVV  300

Query  310   RKLIADAEKNGVGQTYLIQHSAGSGKSNSITWAAYQLIEAYPGNETAAGGKSLEQPLFDS  369
             R+L+ +   NGVGQTYLIQHSAGSGKSNSITWAAYQLIE+YP ++  +G+++ E PLFDS
Sbjct  301   RRLVDHCSVNGVGQTYLIQHSAGSGKSNSITWAAYQLIETYPISDDLPGSRGKEVPLFDS  360

Query  370   VIVVTDRRILDKQLRENIQQFSEVKNIIVPANKSSELKSALEQGkkiiittiqkfpfiiD  429
             VIVVTDRR+LDKQLR+NI++FSEVKNI+ PA KSSELKSALE+GKKIIITTIQKFP+I+D
Sbjct  361   VIVVTDRRLLDKQLRDNIKEFSEVKNIVAPAFKSSELKSALENGKKIIITTIQKFPYIVD  420

Query  430   GISDLSDKRFAVIIDEAHSSQSGSAHDNMNRAMGNVEEEADAQDKILEAMKSRKMRGNAS  489
             GI+DLSD+RFAVIIDEAHSSQ G  +D++N AMG V E  D  DK L++ K+RKMR+NAS
Sbjct  421   GIADLSDRRFAVIIDEAHSSQDGHNQDKLNEAMGFVSE--DVLDKALQSAKNRKMRSNAS  478

Query  490   YLAFTATPKNTTLEKFGQKQPDGSYKPFHLYSMKQAIEEDFILDVLASYNTYKSYYEIEK  549
             Y+AFTATPKNTTLEKFGQ+Q+DG+Y PFHLYSMKQAIEE+FILDV+A+Y TYKSYYEIEK
Sbjct  479   YFAFTATPKNTTLEKFGQRQADGTYVPFHLYSMKQAIEEGFILDVIANYTTYKSYYEIEK  538

Query  550   SISENPLFNSKKAQKKLKGFVERQQQTINIKAEIMLDHFIPHVVNPKLLKGKAKGMVVTQ  609
             SI +NP F+SKKAQK+L+++VE  Q+TI+ KAEIML+HFI HVVN K LKGK+KGMVVTQ
Sbjct  539   SIQDNPEFDSKKAQKRLRAYVEASQETIDTKAEIMLEHFIKHVVNGKKLKGKGKGMVVTQ  598

Query  610   NIETAIRYYKAICRQLKERGNPFKVILAFSGEKTVDGIEYTESEVNGFAd----------  659
             NIE+AIRYY+A+  QL+  GNPFKV +AFSG K VDGIEYTE+++NGF++          
Sbjct  599   NIESAIRYYRALTIQLNKMGNPFKVAIAFSGSKEVDGIEYTEADINGFPEGDTKDYFDVN  658

Query  660   -------tetkdkfdtdeYRLLIVANKYLTGFDQPKLSAMYVDKKLQGVLAVQALSRLNR  712
                    +      D D YRLL+VANKYLTGFDQPKL AMYVDKKL +VL VQALSRLNR
Sbjct  659   YKRKEPDSPIPKHVDQDAYRLLVVANKYLTGFDQPKLCAMYVDKKLASVLCVQALSRLNR  718

Query  713   SAQKLDKRTEDLFILDFFNSTDDIKKSFDDFYTSTSLSEATDVNVLHEIKDGLDDVGVYE  772
             SA K +K+TEDLF+LDFFNS DDIK +FD FYTST+LSEATDVNVLHE+KD++DD GVYE
Sbjct  719   SAPKYGKKTEDLFVLDFFNSVDDIKTAFDPFYTSTTLSEATDVNVLHELKDDMDDTGVYE  778

Query  773   WSEVEEFTKRYFDGDDAQELSILLDVAVNRFEHELQLEQDDQADFKIKAKQFVKIYGQMA  832
             W EVEEF KR+F+G +AQ+LS ++D+A  RF+HEL+LE++ + DFK+KAKQFVKIYGQ+A
Sbjct  779   WFEVEEFNKRFFEGREAQDLSPIIDIAAARFNHELELENEFKVDFKVKAKQFVKIYGQIA  838

Query  833   SIMPYEVVVWEKLYWFLKFLIPKLKIEDTDADQIDELLESVDLSSYGLQRVKLNHTIELD  892
             SIMPYEVV WEKL+WFLKFLIPKL +ED D + +D LL+SVDLSSYGLQRVKLNH+IELD
Sbjct  839   SIMPYEVVQWEKLFWFLKFLIPKLSVEDPDKEALDSLLDSVDLSSYGLQRVKLNHSIELD  898

Query  893   DSETEVDPQNPNVRGSHGGDEEFDPLDDIIRNFNERFFDGWSATPEEQKVKFVNIQANIQ  952
             DSETE+DPQNPN RG+ G + E DPLD+II+ FNER F+GWSATPEEQ+VKFVNI  +I+
Sbjct  899   DSETELDPQNPNPRGAYGPEAEKDPLDEIIKIFNERWFQGWSATPEEQRVKFVNIAESIR  958

Query  953   DHPDFEEKYKNNPDPHTRELAFEKIFNEVMLKRRREDMELYKLLAKDASMKSSVIHSMQS  1012
             +HPDFE KY+NN+DPHTRELAFEK+++E+ML+RR++++ELYKL+A+D++ K+S  +SMQ 
Sbjct  959   NHPDFEAKYQNNADPHTRELAFEKMLKEIMLQRRKDELELYKLFAQDPAFKASWTQSMQR  1018

Query  1013  RIG  1015
              +G
Sbjct  1019  MVG  1021

30) HICON_03820 in NC_014922


> EU272902|14|G13|167832520|ACA01830.1|Vibrio_cholerae_Amazonia_3509|-|13968..17036|-|VPI2_0013c|type 
I restriction enzyme 
HsdR
Length=1022

 Score = 1118 bits (4239),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 690/1026 (68%), Positives = 867/1026 (85%), Gaps = 29/1026 (2%)

Query  1     MVSGTKEKDLEIAIEKALTGTWRENMENKLGEPKAEYLPRHHGFELAFSQDFDAQFAIDT  60
             MVS T+E+ LE AIEK+L+G  +E++   LGE+  +Y   ++ + ++ + DFD Q+A+DT
Sbjct  4     MVSKTNEQALEAAIEKGLAGICKEELA--LGEAPLNY--NNDLYLIGSPSDFDKQYALDT  59

Query  61    RLSWQFLQTSQEAELGRFQQLNPNDWQRKILERLDRQIKKNGVLHLLKKGLDIDSAHFDL  120
             RL WQFL+ +Q +EL ++++ +P+DWQRKILER+DR I ++GVL+LLKKGLD+D A + L
Sbjct  60    RLFWQFLEDTQASELEKLKRTSPHDWQRKILERFDRMIMRHGVLRLLKKGLDVDDAFLSL  119

Query  121   LYPVPLASSGEKVKQRFEQNLFSCMRQVPYSASSN-ETVDMVLFVNGLPIITLELKNHWT  179
             +YP PLASS+EKVK+ F  NLFS  RQV YS ++  E +DMVLF+NG+P+ITLELKN WT
Sbjct  120   MYPAPLASSSEKVKKDFSANLFSVTRQVCYSNANPLEEIDMVLFINGIPLITLELKNPWT  179

Query  180   GQTAI-DAQKQYRN-RDLSQTLFHFGRCLAHFALDTEEAYMTTKLAGPATFFLPFnlgnn  237
             GQ A+ ++QKQYR+ RD +Q L++F+RCL H A+DT+E YMTTKLAG  TFFLPFN G N
Sbjct  180   GQNAVYHGQKQYRDDRDANQPLLNFARCLVHMAVDTDEVYMTTKLAGKNTFFLPFNKGFN  239

Query  238   cgkgnppnpngHRTAYLWQEVFGKASLANIIQHFMRLDGSTKDPLDKRTLFFPRYHQLEV  297
              GKGNP NP+GH+TAYLWQEVF K S+ANIIQHF+RLDGS+K  LDKRTLFFPRYHQ++V
Sbjct  240   FGKGNPINPHGHKTAYLWQEVFRKESIANIIQHFIRLDGSSKKQLDKRTLFFPRYHQMDV  299

Query  298   VRHLIADVSEQGVGKRYLIQHSAGSGKSNSITWLAYQLIEAYPRNKQAANGREADRPIFD  357
             VR+L+ + S +GVG+ YLIQHSAGSGKSNSITW AYQLIE+YP + + + +R  + P+FD
Sbjct  300   VRRLVDHCSVNGVGQTYLIQHSAGSGKSNSITWAAYQLIETYPISDDLPGSRGKEVPLFD  359

Query  358   SVIVVTDRRLLDKQLRDNIKDFSEVKNIVAPALSSAELRQSLEQGkkiiittiQKFPFIV  417
             SVIVVTDRRLLDKQLRDNIK+FSEVKNIVAPA+ S+EL+ +LE+GKKIIITTIQKFP+IV
Sbjct  360   SVIVVTDRRLLDKQLRDNIKEFSEVKNIVAPAFKSSELKSALENGKKIIITTIQKFPYIV  419

Query  418   DGIADLGDKQFAVIIDEAHSSQSGSAHDNMNRAIGKTEDLDAEDVQDLILQTIQSRKMHG  477
             DGIADL+D++FAVIIDEAHSSQ G  +D++N A+G    + +EDV D  LQ+ ++RKM++
Sbjct  420   DGIADLSDRRFAVIIDEAHSSQDGHNQDKLNEAMG----FVSEDVLDKALQSAKNRKMRS  475

Query  478   NASYFAFTATPKNSTLEKFGEKQADGKFKPFHLYSMKQAIEEGFILDVIANYTTYKSFYE  537
             NASYFAFTATPKN+TLEKFG++QADG + PFHLYSMKQAIEEGFILDVIANYTTYKS+YE
Sbjct  476   NASYFAFTATPKNTTLEKFGQRQADGTYVPFHLYSMKQAIEEGFILDVIANYTTYKSYYE  535

Query  538   ITKSIEDNPEFDSKKAQSRLKAYVERSQQTIDTKAEIMLDHFIRQIFNRKKLKGKAKGMV  597
             I KSI+DNPEFDSKKAQ RL+AYVE SQ+TIDTKAEIML+HFI+++ N KKLKGK+KGMV
Sbjct  536   IEKSIQDNPEFDSKKAQKRLRAYVEASQETIDTKAEIMLEHFIKHVVNGKKLKGKGKGMV  595

Query  598   VTQNIETAIRYFQALKHLLAGRGNPFKIAIAFSGSKVVDGVEYTEAEMNGFAESETKEYF  657
             VTQNIE+AIRY++AL   L   GNPFK+AIAFSGSK VDG+EYTEA++NGF+E++TK+YF
Sbjct  596   VTQNIESAIRYYRALTIQLNKMGNPFKVAIAFSGSKEVDGIEYTEADINGFPEGDTKDYF  655

Query  658   -----------------DQDEYRLLVVANKYLTGFDQPKLCAMYVDKKLSGVLCVQALSR  700
                              DQD YRLLVVANKYLTGFDQPKLCAMYVDKKL++VLCVQALSR
Sbjct  656   DVNYKRKEPDSPIPKHVDQDAYRLLVVANKYLTGFDQPKLCAMYVDKKLASVLCVQALSR  715

Query  701   LNRSANKLSKRTEDLFVLDFFNSVEDIQQAFKPFYTSTSLSQATDVNVLHDLKDRLDETG  760
             LNRSA K +K+TEDLFVLDFFNSV+DI+ AF PFYTST+LS+ATDVNVLH+LKD +D+TG
Sbjct  716   LNRSAPKYGKKTEDLFVLDFFNSVDDIKTAFDPFYTSTTLSEATDVNVLHELKDDMDDTG  775

Query  761   VYEQAEVNDFTEGYFANKDAQQLSSMIDVAVQRFDDELDLDRNEKVDFKIKAKQFLKIYG  820
             VYE  EV++F   +F  ++AQ+LS++ID+A  RF++EL+L+ + KVDFK+KAKQF+KIYG
Sbjct  776   VYEWFEVEEFNKRFFEGREAQDLSPIIDIAAARFNHELELENEFKVDFKVKAKQFVKIYG  835

Query  821   QTASIINFENIAWEKLYWFLKFLVPKLKVQDP-MDEFDEILDAVDLSSYGLARTKLNYSI  879
             Q ASI+ +E + WEKL+WFLKFL+PKL V+DP  + +D +LD+VDLSSYGL R KLN SI
Sbjct  836   QIASIMPYEVVQWEKLFWFLKFLIPKLSVEDPDKEALDSLLDSVDLSSYGLQRVKLNHSI  895

Query  880   KLDDEETGLDPQNPNPRGTHGEDKEKDPIDEIIRVFNERWFQGWSAMPDEQRVKFINITE  939
              LDD ET LDPQNPNPRG+ G + EKDP+DEII++FNERWFQGWSA P+EQRVKF+NI+E
Sbjct  896   ELDDSETELDPQNPNPRGAYGPEAEKDPLDEIIKIFNERWFQGWSATPEEQRVKFVNIAE  955

Query  940   RIRNHKDFEQKYQNNPDIHTRELAFQAILRDVMSERHRDELELYKLFAKDAAFRTAWTQS  999
              IRNH DFE KYQNN+D HTRELAF+ +L+++M +R++DELELYKLFA+D+AF+++WTQS
Sbjct  956   SIRNHPDFEAKYQNNADPHTRELAFEKMLKEIMLQRRKDELELYKLFAQDPAFKASWTQS  1015

Query  1000  LQRALA  1005
             +QR ++
Sbjct  1016  MQRMVG  1021

31) hsdR2 in NC_017451


> EU272902|14|G13|167832520|ACA01830.1|Vibrio_cholerae_Amazonia_3509|-|13968..17036|-|VPI2_0013c|type 
I restriction enzyme 
HsdR
Length=1022

 Score = 1118 bits (4239),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 687/1026 (67%), Positives = 869/1026 (85%), Gaps = 29/1026 (2%)

Query  1     MVSGTKEKDLEIAIEKALTGTWRENMENNLGEPKAEYLPRHHGFELAFSQDFDALFAIDT  60
             MVS T+E+ LE AIEK+L+G  +E++   LGE+  +Y   ++ + ++ + DFD  +A+DT
Sbjct  4     MVSKTNEQALEAAIEKGLAGICKEEL--ALGEAPLNY--NNDLYLIGSPSDFDKQYALDT  59

Query  61    RLFWQFLQTSQKAELARFQQLNPNDWQRKILERLDRQIKKNSVLHLLKKGVDIDSAHFDL  120
             RLFWQFL+ +Q +EL ++++ +P+DWQRKILER+DR I +++VL+LLKKG+D+D A + L
Sbjct  60    RLFWQFLEDTQASELEKLKRTSPHDWQRKILERFDRMIMRHGVLRLLKKGLDVDDAFLSL  119

Query  121   LYPVPLASSGEKIKQRFEQNLFSCMRQVPYSASSN-ETVDMVLFVNGLPIITLELKNHWT  179
             +YP PLASS+EK+K+ F  NLFS  RQV YS ++  E +DMVLF+NG+P+ITLELKN WT
Sbjct  120   MYPAPLASSSEKVKKDFSANLFSVTRQVCYSNANPLEEIDMVLFINGIPLITLELKNPWT  179

Query  180   GQTAI-DAQKQYRN-RDLSQTLFHFGRCLAYFALDTEEAYMTTKLAGPATFFLPFnlgnn  237
             GQ A+ ++QKQYR+ RD +Q L++F+RCL   A+DT+E YMTTKLAG  TFFLPFN G N
Sbjct  180   GQNAVYHGQKQYRDDRDANQPLLNFARCLVHMAVDTDEVYMTTKLAGKNTFFLPFNKGFN  239

Query  238   cgkgnppnpngHRTAYLWQEVFGKASLANIIQHFMRLDGSTKDPLEKRSLFFPRYHQLEV  297
              GKGNP NP+GH+TAYLWQEVF K S+ANIIQHF+RLDGS+K  L+KR+LFFPRYHQ++V
Sbjct  240   FGKGNPINPHGHKTAYLWQEVFRKESIANIIQHFIRLDGSSKKQLDKRTLFFPRYHQMDV  299

Query  298   VRRLIADVSEQGVGKRYLIQHSAGSGKSNSITWLAYQLIEAYPCNEKAANGREADRPIFD  357
             VRRL+ + S +GVG+ YLIQHSAGSGKSNSITW AYQLIE+YP ++  + +R  + P+FD
Sbjct  300   VRRLVDHCSVNGVGQTYLIQHSAGSGKSNSITWAAYQLIETYPISDDLPGSRGKEVPLFD  359

Query  358   SVIVVTDRRLLDKQLRDNIKDFSEVKNIVAPALSSAELRQSLEQGkkiiittiQKFPFIV  417
             SVIVVTDRRLLDKQLRDNIK+FSEVKNIVAPA+ S+EL+ +LE+GKKIIITTIQKFP+IV
Sbjct  360   SVIVVTDRRLLDKQLRDNIKEFSEVKNIVAPAFKSSELKSALENGKKIIITTIQKFPYIV  419

Query  418   DGIADLGDKQFAVIIDEAHSSQSGSAHDNMNRAIGKTEDLDAEDVQDLILQAMQSRKMRG  477
             DGIADL+D++FAVIIDEAHSSQ G  +D++N A+G    + +EDV D  LQ+ ++RKMR+
Sbjct  420   DGIADLSDRRFAVIIDEAHSSQDGHNQDKLNEAMG----FVSEDVLDKALQSAKNRKMRS  475

Query  478   NASYFAFTATPKNSTLEKFGEKQADGKFKPFHLYSMKQAIEEGFILDVIANYTTYKSFYE  537
             NASYFAFTATPKN+TLEKFG++QADG + PFHLYSMKQAIEEGFILDVIANYTTYKS+YE
Sbjct  476   NASYFAFTATPKNTTLEKFGQRQADGTYVPFHLYSMKQAIEEGFILDVIANYTTYKSYYE  535

Query  538   ITKSIEDNPEFDSKKAQSRLKAYVERSQQTIDTKAEIMLDHFIRQIFNRKKLKGKAKGMV  597
             I KSI+DNPEFDSKKAQ RL+AYVE SQ+TIDTKAEIML+HFI+++ N KKLKGK+KGMV
Sbjct  536   IEKSIQDNPEFDSKKAQKRLRAYVEASQETIDTKAEIMLEHFIKHVVNGKKLKGKGKGMV  595

Query  598   VTQNIETAIRYFQALKRLLAGRGNPFKIAIAFSGSKVVDGVEYTEAEMNGFAESETKEYF  657
             VTQNIE+AIRY++AL   L   GNPFK+AIAFSGSK VDG+EYTEA++NGF+E++TK+YF
Sbjct  596   VTQNIESAIRYYRALTIQLNKMGNPFKVAIAFSGSKEVDGIEYTEADINGFPEGDTKDYF  655

Query  658   -----------------DQDEYRLLVVANKYLTGFDQPKLCAMYVDKKLSGVLCVQALSR  700
                              DQD YRLLVVANKYLTGFDQPKLCAMYVDKKL++VLCVQALSR
Sbjct  656   DVNYKRKEPDSPIPKHVDQDAYRLLVVANKYLTGFDQPKLCAMYVDKKLASVLCVQALSR  715

Query  701   LNRSANKLGKRTEDLFVLDFFNSVEDIQQAFEPFYTSTSLSQATDVNVLHDLKDRLDETG  760
             LNRSA K GK+TEDLFVLDFFNSV+DI+ AF+PFYTST+LS+ATDVNVLH+LKD +D+TG
Sbjct  716   LNRSAPKYGKKTEDLFVLDFFNSVDDIKTAFDPFYTSTTLSEATDVNVLHELKDDMDDTG  775

Query  761   VYEQAEVDDFTEGYFANKDAQQLSSMIDVAVRRFDDELDLDRNEKVDFKIKAKQFLKIYG  820
             VYE  EV++F   +F  ++AQ+LS++ID+A  RF++EL+L+ + KVDFK+KAKQF+KIYG
Sbjct  776   VYEWFEVEEFNKRFFEGREAQDLSPIIDIAAARFNHELELENEFKVDFKVKAKQFVKIYG  835

Query  821   QMASIINFENIAWEKLYWFLKFLVPKLKVQDP-MDEFDEILDAVDLSSYGLARTKLNYSI  879
             Q+ASI+ +E + WEKL+WFLKFL+PKL V+DP  + +D +LD+VDLSSYGL R KLN SI
Sbjct  836   QIASIMPYEVVQWEKLFWFLKFLIPKLSVEDPDKEALDSLLDSVDLSSYGLQRVKLNHSI  895

Query  880   KLDDEETGLDPQNPNPRGTHGEDKEKDPIDEIIRVFNERWFQGWSATPDEQRVKFINITE  939
              LDD ET LDPQNPNPRG+ G + EKDP+DEII++FNERWFQGWSATP+EQRVKF+NI+E
Sbjct  896   ELDDSETELDPQNPNPRGAYGPEAEKDPLDEIIKIFNERWFQGWSATPEEQRVKFVNIAE  955

Query  940   RIRSHKDFEQKYQNNPDIHTRELAFQAILRDVMSERHRDELELYKLFAKDAAFRTAWTQS  999
              IR+H DFE KYQNN+D HTRELAF+ +L+++M +R++DELELYKLFA+D+AF+++WTQS
Sbjct  956   SIRNHPDFEAKYQNNADPHTRELAFEKMLKEIMLQRRKDELELYKLFAQDPAFKASWTQS  1015

Query  1000  LQRALA  1005
             +QR ++
Sbjct  1016  MQRMVG  1021

32) Runsl_4460 in NC_015703


> EU272902|14|G13|167832520|ACA01830.1|Vibrio_cholerae_Amazonia_3509|-|13968..17036|-|VPI2_0013c|type 
I restriction enzyme 
HsdR
Length=1022

 Score = 1112 bits (4215),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 684/1030 (67%), Positives = 839/1030 (82%), Gaps = 33/1030 (3%)

Query  1     MPSQTNEQALESAIEKRLTGTCLEDLNTNGAVGNVAERAELYRAGNGYYLGTPQDFNAQY  60
             M S+TNEQALE+AIEK L+G C E+L    A+G+ +    L    + Y +G+P DF+ QY
Sbjct  4     MVSKTNEQALEAAIEKGLAGICKEEL----ALGEAP----LNYNNDLYLIGSPSDFDKQY  55

Query  61    AVDERRLWHFLETTQKEELAKLQKNA--DWKLKILERIDRMVKKYGILRLLRKGLEVEDA  118
             A+D R +W+FLE TQ  EL KL++ +  DW+ KILER+DRM+ + G+LRLL+KGL+V+DA
Sbjct  56    ALDTRLFWQFLEDTQASELEKLKRTSPHDWQRKILERFDRMIMRHGVLRLLKKGLDVDDA  115

Query  119   HFTMLYSLPLASSSQAVKDNFESNEFSVTRQIRYSLTNPREEIDMVLFVNGLPLVTMELK  178
              ++++Y+ PLASSS+ VK +F +N FSVTRQ+ YS +NP EEIDMVLF+NG+PL+T+ELK
Sbjct  116   FLSLMYPAPLASSSEKVKKDFSANLFSVTRQVCYSNANPLEEIDMVLFINGIPLITLELK  175

Query  179   NQWTGQNAKVHGQNQYRNDRDTTQPLLHFGRCIVHFAVDPDEAYMTTKLNGKDTFFLPFN  238
             N WTGQNA  HGQ+QYR+DRD+ QPLL+F+RC+VH AVD DE YMTTKL GK+TFFLPFN
Sbjct  176   NPWTGQNAVYHGQKQYRDDRDANQPLLNFARCLVHMAVDTDEVYMTTKLAGKNTFFLPFN  235

Query  239   LGHNYGKGNPPNPFGHKTAYLW-EVFTRQSLTNIIQHFVRFDGKDTDTLAKRNLFFPRYH  297
              G N+GKGNP NP GHKTAYLW EVF ++S++NIIQHF+R+DG     L KR LFFPRYH
Sbjct  236   KGFNFGKGNPINPHGHKTAYLWQEVFRKESIANIIQHFIRLDGSSKKQLDKRTLFFPRYH  295

Query  298   QLDVVRKLIQDASKKGVGQTYLIQHSAGSGKSNSITWAAYQLIETYPENDTVPGSRGITH  357
             Q+DVVR+L+++ S +GVGQTYLIQHSAGSGKSNSITWAAYQLIETYP +D +PGSRG   
Sbjct  296   QMDVVRRLVDHCSVNGVGQTYLIQHSAGSGKSNSITWAAYQLIETYPISDDLPGSRGKEV  355

Query  358   PLFDSVIVVTDRRLLDKQLRENISDFSEVKNIVAPAHsskelkeslesGKRIIITTIQKF  417
             PLFDSVIVVTDRRLLDKQLR+NI +FSEVKNIVAPA  S ELK +LE+GK+IIITTIQKF
Sbjct  356   PLFDSVIVVTDRRLLDKQLRDNIKEFSEVKNIVAPAFKSSELKSALENGKKIIITTIQKF  415

Query  418   PFIVDGIADMSHKRFAVIIDEAHSSQSGSTADNMNRVMGKKAeeeeeedpedIILKAMKT  477
             P+IVDGIAD+S++RFAVIIDEAHSSQ G   D++N  MG        ED  D  L++ K 
Sbjct  416   PYIVDGIADLSDRRFAVIIDEAHSSQDGHNQDKLNEAMG-----FVSEDVLDKALQSAKN  470

Query  478   RKMRGNASYLAFTATPKNATLEKFGIRQEDGKFKPFHEYTMKQAIEEGFILDVLANYTTY  537
             RKMR+NASY+AFTATPKN+TLEKFG RQ DG + PFH Y+MKQAIEEGFILDV+ANYTTY
Sbjct  471   RKMRSNASYFAFTATPKNTTLEKFGQRQADGTYVPFHLYSMKQAIEEGFILDVIANYTTY  530

Query  538   KSYYEIEKSIEDNPLFDTAKAQKKLKAYVERDARTIATKADILLDHFITKVVNPKKLKGK  597
             KSYYEIEKSI+DNP FD+ KAQK+L+AYVE    TI TKA+I+L+HFI  VVN KKLKGK
Sbjct  531   KSYYEIEKSIQDNPEFDSKKAQKRLRAYVEASQETIDTKAEIMLEHFIKHVVNGKKLKGK  590

Query  598   AKAMVVTQSIESAIRYFFALRQLLNEKGNPFNIVIAFSGKKTVDGIEYTEESINGFAEKD  657
             +K+MVVTQ+IESAIRY+ AL   LN  GNPF++ IAFSG K VDGIEYTE  INGF+E D
Sbjct  591   GKGMVVTQNIESAIRYYRALTIQLNKMGNPFKVAIAFSGSKEVDGIEYTEADINGFPEGD  650

Query  658   TRDKFD-----------------QDDYRMLVVANKYLTGFDQPKLTAMYVDKKLQDVLAV  700
             T+D FD                 QD YR+LVVANKYLTGFDQPKL AMYVDKKL  VL V
Sbjct  651   TKDYFDVNYKRKEPDSPIPKHVDQDAYRLLVVANKYLTGFDQPKLCAMYVDKKLASVLCV  710

Query  701   QALSRLNRSADKLGKKTEDLFVLDFFNSTDDIKVAFDPFYTATTLSKATDVNVLHDLKGH  760
             QALSRLNRSA K GKKTEDLFVLDFFNS DDIK AFDPFYT+TTLS ATDVNVLH+LK++
Sbjct  711   QALSRLNRSAPKYGKKTEDLFVLDFFNSVDDIKTAFDPFYTSTTLSEATDVNVLHELKDD  770

Query  761   LDDVGVYEWAEVEDFVAKYFKGVNAEQLSPIIDLAADRFNQQLELEDAQKADYKIKAKQF  820
             +DD GVYEW EVE+F  ++F G +A++LSPIID+AA RFN++LELE+  K D+K+KAKQF
Sbjct  771   MDDTGVYEWFEVEEFNKRFFEGREAQDLSPIIDIAAARFNHELELENEFKVDFKVKAKQF  830

Query  821   VKIYAQMASILPYEIIKWEKLFWFLKFLIPKLIIVDAGSEALDELLNSVDLSTYGLERVK  880
             VKIY+Q+ASI+PYE+++WEKLFWFLKFLIPKL + D++ EALD LL+SVDLS+YGL+RVK
Sbjct  831   VKIYGQIASIMPYEVVQWEKLFWFLKFLIPKLSVEDPDKEALDSLLDSVDLSSYGLQRVK  890

Query  881   LNTAIGLDASETELEPQNSNVRGVHGDTTQEDPLDLIIRSFNERWFQGWDLTPEEQRVKF  940
             LN +I LD SETEL+PQN+N RG  G  ++ DPLD II+ FNERWFQGW  TPEEQRVKF
Sbjct  891   LNHSIELDDSETELDPQNPNPRGAYGPEAEKDPLDEIIKIFNERWFQGWSATPEEQRVKF  950

Query  941   VTLAQSIQAHPDFKNKYSENQDSQNREIAFRKIFDEVMAKQRKSELDLYRLISKDDAFKT  1000
             V +A+SI+ HPDF  KY +N D++ RE+AF K++ E+M ++RK EL+LY+L+++D AFK+
Sbjct  951   VNIAESIRNHPDFEAKYQNNADPHTRELAFEKMLKEIMLQRRKDELELYKLFAQDPAFKA  1010

Query  1001  AMQDTLKRMI  1010
             +  ++++RM+
Sbjct  1011  SWTQSMQRMV  1020

33) FBFL15_1794 in NC_016001


> EU272902|14|G13|167832520|ACA01830.1|Vibrio_cholerae_Amazonia_3509|-|13968..17036|-|VPI2_0013c|type 
I restriction enzyme 
HsdR
Length=1022

 Score = 1108 bits (4201),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 679/1030 (66%), Positives = 825/1030 (81%), Gaps = 31/1030 (3%)

Query  1     MPTQTNEAALEATIQKKLTGTCLEELKSDSSNTVNERVELYRSGKGYYIGFANDFNAKYA  60
             M ++TNE ALEA+I+K L+G C EEL + +   +N   +LY       IG ++DF+ +YA
Sbjct  4     MVSKTNEQALEAAIEKGLAGICKEEL-ALGEAPLNYNNDLY------LIGSPSDFDKQYA  56

Query  61    IDEVRFWHFLETTQKEELAKIQK--QNDWKLKILDRLDRMIKKYGILRLLRKGLEVDDAH  118
             +D   FW+FLE TQ  EL K+++   +DW+ KIL+R+DRMI + G+LRLL+KGL+VDDA 
Sbjct  57    LDTRLFWQFLEDTQASELEKLKRTSPHDWQRKILERFDRMIMRHGVLRLLKKGLDVDDAF  116

Query  119   FTLMYVLPLASSSAAAKTNFENNEFSVSRQIRYSLLNPREEIDMVVFVNGLPIATMELKN  178
             ++LMY  PLASSS   K +F  N FSV+RQ+ YS  NP EEIDMV+F+NG+P+ T+ELKN
Sbjct  117   LSLMYPAPLASSSEKVKKDFSANLFSVTRQVCYSNANPLEEIDMVLFINGIPLITLELKN  176

Query  179   HWTGQNAKLHGQNQYKTKRDITQPLLNFGRCIVHFAVDTDEVYMTTKLDGANTFFLPFNL  238
              WTGQNA  HGQ+QY+  RD  QPLLNF+RC+VH AVDTDEVYMTTKL G NTFFLPFN 
Sbjct  177   PWTGQNAVYHGQKQYRDDRDANQPLLNFARCLVHMAVDTDEVYMTTKLAGKNTFFLPFNK  236

Query  239   GHNYGKGNPPNPFGHKTAYLWDEVLTRESLANIIQHFVRFDGKETDVLSKKNLFFPRYHQ  298
             G N+GKGNP NP GHKTAYLW+EV+ +ES+ANIIQHF+R+DG     L K+ LFFPRYHQ
Sbjct  237   GFNFGKGNPINPHGHKTAYLWQEVFRKESIANIIQHFIRLDGSSKKQLDKRTLFFPRYHQ  296

Query  299   MNVVRKLIAHASKNGVGQTYLIQHSAGSGKSNSITWAAYQLIETYPESETTPGSRGVNNP  358
             M+VVR+L+ H S NGVGQTYLIQHSAGSGKSNSITWAAYQLIETYP S+  PGSRG + P
Sbjct  297   MDVVRRLVDHCSVNGVGQTYLIQHSAGSGKSNSITWAAYQLIETYPISDDLPGSRGKEVP  356

Query  359   LFDSVIVVTDRRLLDKQLRENIKEFSEVKNIVAPAYSSKELKENLESGKRIIITTIQKFP  418
             LFDSVIVVTDRRLLDKQLR+NIKEFSEVKNIVAPA+ S ELK  LE+GK+IIITTIQKFP
Sbjct  357   LFDSVIVVTDRRLLDKQLRDNIKEFSEVKNIVAPAFKSSELKSALENGKKIIITTIQKFP  416

Query  419   FIVDGIADLSDKRFAVIIDEAHSSQSGSAADNMNRAMGSNSSEEDEEDPQDKILEIMRSR  478
             +IVDGIADLSD+RFAVIIDEAHSSQ G   D++N AMG  S     ED  DK L+  ++R
Sbjct  417   YIVDGIADLSDRRFAVIIDEAHSSQDGHNQDKLNEAMGFVS-----EDVLDKALQSAKNR  471

Query  479   KMSKNASYLAFTATPKSNTLEKFGELQEDGKFKPFHLYSMKQAIEEGFILDVLANYTTYK  538
             KM  NASY+AFTATPK+ TLEKFG+ Q DG + PFHLYSMKQAIEEGFILDV+ANYTTYK
Sbjct  472   KMRSNASYFAFTATPKNTTLEKFGQRQADGTYVPFHLYSMKQAIEEGFILDVIANYTTYK  531

Query  539   SYYEIEKSIEENPLFDTNKAQKKLRAFVEQHKQTIAIKADIVVDHFITKIVNTKKLKGKA  598
             SYYEIEKSI++NP FD++KAQK+LRA+VE  ++TI  KA+I+++HFI  +VN KKLKGK+
Sbjct  532   SYYEIEKSIQDNPEFDSKKAQKRLRAYVEASQETIDTKAEIMLEHFIKHVVNGKKLKGKG  591

Query  599   KAMMVTQSIESAIKYFFAIQKILQEKGTPFKAVIAFSGKKKIDGIEYTEDSINGFAEKDT  658
             K+M+VTQ+IESAI+Y+ A+   L+  G PFK  IAFSG K +DGIEYTE  INGF+E DT
Sbjct  592   KGMVVTQNIESAIRYYRALTIQLNKMGNPFKVAIAFSGSKEVDGIEYTEADINGFPEGDT  651

Query  659   RDKF-----------------DSDDYKILVVANKYLTGFDQPKLTAMYVDKKLQGVLAVQ  701
             +D F                 D D Y++LVVANKYLTGFDQPKL AMYVDKKL +VL VQ
Sbjct  652   KDYFDVNYKRKEPDSPIPKHVDQDAYRLLVVANKYLTGFDQPKLCAMYVDKKLASVLCVQ  711

Query  702   ALSRLNRAANKLGKKTEDLFVLDFFNSTEDMKDAFDPFYTATSLNKATDVNVLHEIKAIL  761
             ALSRLNR+A K GKKTEDLFVLDFFNS +D+K AFDPFYT+T+L+ ATDVNVLHE+K  +
Sbjct  712   ALSRLNRSAPKYGKKTEDLFVLDFFNSVDDIKTAFDPFYTSTTLSEATDVNVLHELKDDM  771

Query  762   DDVGVYEWSEVEDFVDKYFKKVDAQLLSPIIDIAADRFNFQLELEDSEKADFKIKAKQFV  821
             DD GVYEW EVE+F  ++F   +AQ LSPIIDIAA RFN +LELE+  K DFK+KAKQFV
Sbjct  772   DDTGVYEWFEVEEFNKRFFEGREAQDLSPIIDIAAARFNHELELENEFKVDFKVKAKQFV  831

Query  822   KIYGQMASILPYEIVNWEKLFWFLKFLIPKLIIVDGNIDALDELLNSVDLSTYGLERVKL  881
             KIYGQ+ASI+PYE+V+WEKLFWFLKFLIPKL + D + +ALD LL+SVDLS+YGL+RVKL
Sbjct  832   KIYGQIASIMPYEVVQWEKLFWFLKFLIPKLSVEDPDKEALDSLLDSVDLSSYGLQRVKL  891

Query  882   NSSIGLDDSETELDPQNPNPRGAHGTDKEEDPLDLIINSFNERWFQGWEATPEEQRVKFV  941
             N SI LDDSETELDPQNPNPRGA G + E DPLD II+ FNERWFQGW ATPEEQRVKFV
Sbjct  892   NHSIELDDSETELDPQNPNPRGAYGPEAEKDPLDEIIKIFNERWFQGWSATPEEQRVKFV  951

Query  942   TLAKSIKAHPDYLEKYSENTDVQNREIAFRKIFDEVMAQQRKIELDLYKKVTQDDSFRIA  1001
              +A SI+ HPD+  KY +N+D + RE+AF K++ E+M Q+RK EL+LYK  +QD +F+ +
Sbjct  952   NIAESIRNHPDFEAKYQNNADPHTRELAFEKMLKEIMLQRRKDELELYKLFAQDPAFKAS  1011

Query  1002  MQDTLKRILS  1011
               ++++R+++
Sbjct  1012  WTQSMQRMVG  1021

34) hsdR1 in NC_014920


> EU272902|14|G13|167832520|ACA01830.1|Vibrio_cholerae_Amazonia_3509|-|13968..17036|-|VPI2_0013c|type 
I restriction enzyme 
HsdR
Length=1022

 Score = 1103 bits (4182),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 692/1028 (68%), Positives = 868/1028 (85%), Gaps = 31/1028 (3%)

Query  1     MVSGTKEKDLEIAIEKALTGTWRENMENKLGEPKAEYLPRHHGFKLAFSQDFDAQFAIDT  60
             MVS T+E+ LE AIEK+L+G  +E++   LGE+  +Y   ++ + ++ + DFD Q+A+DT
Sbjct  4     MVSKTNEQALEAAIEKGLAGICKEELA--LGEAPLNY--NNDLYLIGSPSDFDKQYALDT  59

Query  61    RLFWQFLQTSQEAELARFQQLNPNDWQRKILERLDRQIKKNGVLHLLKKGLDIDSAHFDL  120
             RLFWQFL+ +Q +EL ++++ +P+DWQRKILER+DR I ++GVL+LLKKGLD+D A + L
Sbjct  60    RLFWQFLEDTQASELEKLKRTSPHDWQRKILERFDRMIMRHGVLRLLKKGLDVDDAFLSL  119

Query  121   LYPVPLASSGEKVKQRFEQNLFSCMRQVPYSASSN-ETVDMVLFVNGLPIITLELKNHWT  179
             +YP PLASS+EKVK+ F  NLFS  RQV YS ++  E +DMVLF+NG+P+ITLELKN WT
Sbjct  120   MYPAPLASSSEKVKKDFSANLFSVTRQVCYSNANPLEEIDMVLFINGIPLITLELKNPWT  179

Query  180   GQTAI-DAQKQYLN-RDLSQTLFHFGRCLAHFALDTEEAYMTTKLAGPATFFLPFnlgnn  237
             GQ A+ ++QKQY + RD +Q L++F+RCL H A+DT+E YMTTKLAG  TFFLPFN G N
Sbjct  180   GQNAVYHGQKQYRDDRDANQPLLNFARCLVHMAVDTDEVYMTTKLAGKNTFFLPFNKGFN  239

Query  238   cgkgnppnpngHRTAYLWQEVFGKASLANIIQHFMRLDGSTKDPLDKRTLFFPRYHQLDV  297
              GKGNP NP+GH+TAYLWQEVF K S+ANIIQHF+RLDGS+K  LDKRTLFFPRYHQ+DV
Sbjct  240   FGKGNPINPHGHKTAYLWQEVFRKESIANIIQHFIRLDGSSKKQLDKRTLFFPRYHQMDV  299

Query  298   VRRLIADVSEHGVGKRYLIQHSAGSGKSNSITWLAYQLIEAYPRNEKAANGREADRPIFD  357
             VRRL+ + S +GVG+ YLIQHSAGSGKSNSITW AYQLIE+YP ++  + +R  + P+FD
Sbjct  300   VRRLVDHCSVNGVGQTYLIQHSAGSGKSNSITWAAYQLIETYPISDDLPGSRGKEVPLFD  359

Query  358   SVIVVTDRRLLDKQLRDNIKDFSEVKNIVAPALSSAELRQSLEQGkkiiittiQKFPFIV  417
             SVIVVTDRRLLDKQLRDNIK+FSEVKNIVAPA+ S+EL+ +LE+GKKIIITTIQKFP+IV
Sbjct  360   SVIVVTDRRLLDKQLRDNIKEFSEVKNIVAPAFKSSELKSALENGKKIIITTIQKFPYIV  419

Query  418   DGIADLGDKQFAVIIDEAHSSQSGSAHDNMNRVIGKTEDLDAEDVQDLILQTMQSRKMHG  477
             DGIADL+D++FAVIIDEAHSSQ G  +D++N  +G    + +EDV D  LQ+ ++RKM++
Sbjct  420   DGIADLSDRRFAVIIDEAHSSQDGHNQDKLNEAMG----FVSEDVLDKALQSAKNRKMRS  475

Query  478   NASYFAFTATPKNSTLEKFGEKQADGKFKPFHLYSMKQAIEEGFILDVIANYTTYKSFYE  537
             NASYFAFTATPKN+TLEKFG++QADG + PFHLYSMKQAIEEGFILDVIANYTTYKS+YE
Sbjct  476   NASYFAFTATPKNTTLEKFGQRQADGTYVPFHLYSMKQAIEEGFILDVIANYTTYKSYYE  535

Query  538   ITKSIEDNPEFDSKKAQSRLKAYVERSQQTIDTKAEIMLDHFIYQVFNRKKLKGKAKGMV  597
             I KSI+DNPEFDSKKAQ RL+AYVE SQ+TIDTKAEIML+HFI +V N KKLKGK+KGMV
Sbjct  536   IEKSIQDNPEFDSKKAQKRLRAYVEASQETIDTKAEIMLEHFIKHVVNGKKLKGKGKGMV  595

Query  598   VTQNIETAIRYFQALKHLLAGRGNPFKIAIAFSGSKVVDGVEYTEAEMNGFAESETKEYF  657
             VTQNIE+AIRY++AL   L   GNPFK+AIAFSGSK VDG+EYTEA++NGF+E++TK+YF
Sbjct  596   VTQNIESAIRYYRALTIQLNKMGNPFKVAIAFSGSKEVDGIEYTEADINGFPEGDTKDYF  655

Query  658   -----------------DQDEYRLLVVANKYLTGFDQPKLCAMYVDKKLSGVLCVQALSR  700
                              DQD YRLLVVANKYLTGFDQPKLCAMYVDKKL++VLCVQALSR
Sbjct  656   DVNYKRKEPDSPIPKHVDQDAYRLLVVANKYLTGFDQPKLCAMYVDKKLASVLCVQALSR  715

Query  701   LNRSANKLSKRTEDLFVLDFFNSVEDIQQAFEPFYTSTSLSQATDVNVLHDLKDRLDETG  760
             LNRSA K +K+TEDLFVLDFFNSV+DI+ AF+PFYTST+LS+ATDVNVLH+LKD +D+TG
Sbjct  716   LNRSAPKYGKKTEDLFVLDFFNSVDDIKTAFDPFYTSTTLSEATDVNVLHELKDDMDDTG  775

Query  761   VYEQAEVNDFTEGYFANKDAQQLSSMIDVAVQRFddeleldldRNEKVDFKIKAKQFLKI  820
             VYE  EV++F   +F  ++AQ+LS++ID+A  RF  + EL+L+ + KVDFK+KAKQF+KI
Sbjct  776   VYEWFEVEEFNKRFFEGREAQDLSPIIDIAAARF--NHELELENEFKVDFKVKAKQFVKI  833

Query  821   YGQMASIINFENIAWEKLYWFLKFLVPKLKVQDP-MDEFDEILDAVDLSSYGLARTKLNY  879
             YGQ+ASI+ +E + WEKL+WFLKFL+PKL V+DP  + +D +LD+VDLSSYGL R KLN 
Sbjct  834   YGQIASIMPYEVVQWEKLFWFLKFLIPKLSVEDPDKEALDSLLDSVDLSSYGLQRVKLNH  893

Query  880   SIKLDDEETELDPQNPNPRGTHGEDKEKDPIDEIIRVFNERWFQDWSATPDEQRVKFINI  939
             SI LDD ETELDPQNPNPRG+ G + EKDP+DEII++FNERWFQ+WSATP+EQRVKF+NI
Sbjct  894   SIELDDSETELDPQNPNPRGAYGPEAEKDPLDEIIKIFNERWFQGWSATPEEQRVKFVNI  953

Query  940   TERIRSHKDFEQKYQNNPDIHTRELAFQAILRDVMSERHRDELELYKLFAKDAAFRTAWT  999
             +E IR+H DFE KYQNN+D HTRELAF+ +L+++M +R++DELELYKLFA+D+AF+++WT
Sbjct  954   AESIRNHPDFEAKYQNNADPHTRELAFEKMLKEIMLQRRKDELELYKLFAQDPAFKASWT  1013

Query  1000  QSLQRALA  1007
             QS+QR ++
Sbjct  1014  QSMQRMVG  1021

35) hsdR1 in NC_007146


> EU272902|14|G13|167832520|ACA01830.1|Vibrio_cholerae_Amazonia_3509|-|13968..17036|-|VPI2_0013c|type 
I restriction enzyme 
HsdR
Length=1022

 Score = 1102 bits (4177),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 692/1028 (68%), Positives = 868/1028 (85%), Gaps = 31/1028 (3%)

Query  1     MVSGTKEKDLEIAIEKALTGTWRENMENKLGEPKAEYLPRHHGFKLAFSQDFDAQFAIDT  60
             MVS T+E+ LE AIEK+L+G  +E++   LGE+  +Y   ++ + ++ + DFD Q+A+DT
Sbjct  4     MVSKTNEQALEAAIEKGLAGICKEELA--LGEAPLNY--NNDLYLIGSPSDFDKQYALDT  59

Query  61    RLFWQFLQTSQEAELARFQQLNPNDWQRKILERLDRQIKKNGVLHLLKKGLDIDSAHFDL  120
             RLFWQFL+ +Q +EL ++++ +P+DWQRKILER+DR I ++GVL+LLKKGLD+D A + L
Sbjct  60    RLFWQFLEDTQASELEKLKRTSPHDWQRKILERFDRMIMRHGVLRLLKKGLDVDDAFLSL  119

Query  121   LYPVPLASSGEKVKQRFEQNLFSCMRQVPYSASSN-ETVDMVLFANGLPIIALELKNHWT  179
             +YP PLASS+EKVK+ F  NLFS  RQV YS ++  E +DMVLF NG+P+I+LELKN WT
Sbjct  120   MYPAPLASSSEKVKKDFSANLFSVTRQVCYSNANPLEEIDMVLFINGIPLITLELKNPWT  179

Query  180   GQTAI-DAQKQYLN-RDLSQTLFHFGRCLAHFALDTEEAYMTTKLAGPATFFLPFnlgnn  237
             GQ A+ ++QKQY + RD +Q L++F+RCL H A+DT+E YMTTKLAG  TFFLPFN G N
Sbjct  180   GQNAVYHGQKQYRDDRDANQPLLNFARCLVHMAVDTDEVYMTTKLAGKNTFFLPFNKGFN  239

Query  238   cgkgnppnpngHRTAYLWQEVFGKASLANIIQHFMRLDGSTKDPLDKRTLFFPRYHQLDV  297
              GKGNP NP+GH+TAYLWQEVF K S+ANIIQHF+RLDGS+K  LDKRTLFFPRYHQ+DV
Sbjct  240   FGKGNPINPHGHKTAYLWQEVFRKESIANIIQHFIRLDGSSKKQLDKRTLFFPRYHQMDV  299

Query  298   VRRLIADVSEHGVGKRYLIQHSAGSGKSNSITWLAYQLIEAYPRNEKAANGREADRPIFD  357
             VRRL+ + S +GVG+ YLIQHSAGSGKSNSITW AYQLIE+YP ++  + +R  + P+FD
Sbjct  300   VRRLVDHCSVNGVGQTYLIQHSAGSGKSNSITWAAYQLIETYPISDDLPGSRGKEVPLFD  359

Query  358   SVIVVTDRRLLDKQLRDNIKDFSEVKNIVAPALSSAELRQSLEQGkkiiittiQKFPFIV  417
             SVIVVTDRRLLDKQLRDNIK+FSEVKNIVAPA+ S+EL+ +LE+GKKIIITTIQKFP+IV
Sbjct  360   SVIVVTDRRLLDKQLRDNIKEFSEVKNIVAPAFKSSELKSALENGKKIIITTIQKFPYIV  419

Query  418   DGIADLGDKQFAVIIDEAHSSQSGSAHDNMNRAIGKTEDLDAEDVQDLILQTMQSRKMHG  477
             DGIADL+D++FAVIIDEAHSSQ G  +D++N A+G    + +EDV D  LQ+ ++RKM++
Sbjct  420   DGIADLSDRRFAVIIDEAHSSQDGHNQDKLNEAMG----FVSEDVLDKALQSAKNRKMRS  475

Query  478   NASYFAFTATPKNSTLEKFGEKQADGKFKPFHLYSMKQAIEEGFILDVIANYTTYKSFYE  537
             NASYFAFTATPKN+TLEKFG++QADG + PFHLYSMKQAIEEGFILDVIANYTTYKS+YE
Sbjct  476   NASYFAFTATPKNTTLEKFGQRQADGTYVPFHLYSMKQAIEEGFILDVIANYTTYKSYYE  535

Query  538   ITKSIEDNPEFDSKKAQSRLKAYVERSQQTIDTKAEIMLDHFIYQVFNRKKLKGKAKGMV  597
             I KSI+DNPEFDSKKAQ RL+AYVE SQ+TIDTKAEIML+HFI +V N KKLKGK+KGMV
Sbjct  536   IEKSIQDNPEFDSKKAQKRLRAYVEASQETIDTKAEIMLEHFIKHVVNGKKLKGKGKGMV  595

Query  598   VTQNIETAIRYFQALKHLLAGRGNPFKIAIAFSGSKVVDGVEYTEAEMNGFAESETKEYF  657
             VTQNIE+AIRY++AL   L   GNPFK+AIAFSGSK VDG+EYTEA++NGF+E++TK+YF
Sbjct  596   VTQNIESAIRYYRALTIQLNKMGNPFKVAIAFSGSKEVDGIEYTEADINGFPEGDTKDYF  655

Query  658   -----------------DQDEYRLLVVANKYLTGFDQPKLCAMYVDKKLSGVLCVQALSR  700
                              DQD YRLLVVANKYLTGFDQPKLCAMYVDKKL++VLCVQALSR
Sbjct  656   DVNYKRKEPDSPIPKHVDQDAYRLLVVANKYLTGFDQPKLCAMYVDKKLASVLCVQALSR  715

Query  701   LNRSANKLSKRTEDLFVLDFFNSVEDIQQAFEPFYTSTSLSQATDVNVLHDLKDRLDETG  760
             LNRSA K +K+TEDLFVLDFFNSV+DI+ AF+PFYTST+LS+ATDVNVLH+LKD +D+TG
Sbjct  716   LNRSAPKYGKKTEDLFVLDFFNSVDDIKTAFDPFYTSTTLSEATDVNVLHELKDDMDDTG  775

Query  761   VYEQAEVNDFTEGYFANKDAQQLSSMIDVAVQRFddeleldldRNEKVDFKIKAKQFLKI  820
             VYE  EV++F   +F  ++AQ+LS++ID+A  RF  + EL+L+ + KVDFK+KAKQF+KI
Sbjct  776   VYEWFEVEEFNKRFFEGREAQDLSPIIDIAAARF--NHELELENEFKVDFKVKAKQFVKI  833

Query  821   YGQMASIINFENIAWEKLYWFLKFLVPKLKVQDP-MDEFDEILDAVDLSSYGLARTKLNY  879
             YGQ+ASI+ +E + WEKL+WFLKFL+PKL V+DP  + +D +LD+VDLSSYGL R KLN 
Sbjct  834   YGQIASIMPYEVVQWEKLFWFLKFLIPKLSVEDPDKEALDSLLDSVDLSSYGLQRVKLNH  893

Query  880   SIKLDDEETELDPQNPNPRGTHGEDKEKDPIDEIIRVFNERWFQDWSATPDEQRVKFINI  939
             SI LDD ETELDPQNPNPRG+ G + EKDP+DEII++FNERWFQ+WSATP+EQRVKF+NI
Sbjct  894   SIELDDSETELDPQNPNPRGAYGPEAEKDPLDEIIKIFNERWFQGWSATPEEQRVKFVNI  953

Query  940   TERIRSHKDFEQKYQNNPDIHTRELAFQAILRDVMSERHRDELELYKLFAKDAAFRTAWT  999
             +E IR+H DFE KYQNN+D HTRELAF+ +L+++M +R++DELELYKLFA+D+AF+++WT
Sbjct  954   AESIRNHPDFEAKYQNNADPHTRELAFEKMLKEIMLQRRKDELELYKLFAQDPAFKASWT  1013

Query  1000  QSLQRALA  1007
             QS+QR ++
Sbjct  1014  QSMQRMVG  1021

36) Slin_6264 in NC_013730


> EU272902|14|G13|167832520|ACA01830.1|Vibrio_cholerae_Amazonia_3509|-|13968..17036|-|VPI2_0013c|type 
I restriction enzyme 
HsdR
Length=1022

 Score = 1089 bits (4129),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 667/1035 (65%), Positives = 842/1035 (82%), Gaps = 35/1035 (3%)

Query  1     MPSHTNEQALEAAIEKKLTGTTREELRTQGITSAWAEAASQYRSGNGYWMGETTDFNAEY  60
             M S TNEQALEAAIEK L+G  +EEL       A +EA+ +Y + + Y +G  +DF+ +Y
Sbjct  4     MVSKTNEQALEAAIEKGLAGICKEEL-------ALGEAPLNY-NNDLYLIGSPSDFDKQY  55

Query  61    AIDTRRFWHFLETTQPLELAKLQ--TQHQWELLILQKVDRLIKKYGVLHLFRKGLDIDDA  118
             A+DTR FW+FLE TQ+ EL KL+  + H+W+  IL++ DR+I + GVL+L++KGLD+DDA
Sbjct  56    ALDTRLFWQFLEDTQASELEKLKRTSPHDWQRKILERFDRMIMRHGVLRLLKKGLDVDDA  115

Query  119   HFTMLYVPPLASSSQSVKDAFERNEFSVTRQLRYSTTNPREEVDMVVFINGLPVATMELK  178
              ++++Y +PLASSS+ VK  F  N FSVTRQ+ YS +NP EE+DMV+FING+P+ T+ELK
Sbjct  116   FLSLMYPAPLASSSEKVKKDFSANLFSVTRQVCYSNANPLEEIDMVLFINGIPLITLELK  175

Query  179   NPWTGQNARVHGIKQYKWDRDATQPLLQFGRCVVHLAVDPDEIFMTTRLSGKDTFFLPFN  238
             NPWTGQNA  HG KQY+ DRDA QPLL+F+RC+VH+AVD DE++MTT+L+GK+TFFLPFN
Sbjct  176   NPWTGQNAVYHGQKQYRDDRDANQPLLNFARCLVHMAVDTDEVYMTTKLAGKNTFFLPFN  235

Query  239   KGDLNHGAGNPPNSFGHKTAYLWEDILTRQSLSTIIQHFVTLDGKSTEPLAKRTLIFPRY  298
             KG +N G GNP N+ GHKTAYLW++++ ++S++ IIQHF+ LDG S   L KRTL+FPRY
Sbjct  236   KG-FNFGKGNPINPHGHKTAYLWQEVFRKESIANIIQHFIRLDGSSKKQLDKRTLFFPRY  294

Query  299   HQLEVVRRLLKNVSQNGVGQTYLIQHSAGSGKSNSITWAAFQLIEAYPESATTPGNRGIT  358
             HQ++VVRRL+ + S NGVGQTYLIQHSAGSGKSNSITWAA+QLIE+YP S   PG+RG  
Sbjct  295   HQMDVVRRLVDHCSVNGVGQTYLIQHSAGSGKSNSITWAAYQLIETYPISDDLPGSRGKE  354

Query  359   LPLFDSVIVVTDRRLLDKQIRENIKEFSQVKNIVAPAFSSQELRQALEggkkiiittiQK  418
             +PLFDSVIVVTDRRLLDKQ+R+NIKEFS+VKNIVAPAF S EL+ ALE GKKIIITTIQK
Sbjct  355   VPLFDSVIVVTDRRLLDKQLRDNIKEFSEVKNIVAPAFKSSELKSALENGKKIIITTIQK  414

Query  419   FPYIIEGISDLSDKKFAVIIDEAHSSQSGTAHDSMNNAMGKTEAKdddqqpdaqdLILAA  478
             FPYI++GI+DLSD++FAVIIDEAHSSQ G  +D +N+AMG       D+        L +
Sbjct  415   FPYIVDGIADLSDRRFAVIIDEAHSSQDGHNQDKLNEAMGFVSEDVLDKA-------LQS  467

Query  479   MQARKMRGNASYFAFTATPKPNTLEKFGTRKDDGTFTPFHLYSMKQAIEEGFILDVLANY  538
              + RKMR+NASYFAFTATPK  TLEKFG R+ DGT+ PFHLYSMKQAIEEGFILDV+ANY
Sbjct  468   AKNRKMRSNASYFAFTATPKNTTLEKFGQRQADGTYVPFHLYSMKQAIEEGFILDVIANY  527

Query  539   TTYRSYYEIEKSIEENPLFDTQKAQKKLKMYVEQHRQTIGTKAEIMVEHFTTQVVNTKKL  598
             TTY+SYYEIEKSI++NP FD++KAQK+L+ YVE  ++TI+TKAEIM+EHF  +VVN KKL
Sbjct  528   TTYKSYYEIEKSIQDNPEFDSKKAQKRLRAYVEASQETIDTKAEIMLEHFIKHVVNGKKL  587

Query  599   KGKAKGMVVTQSIESAIRYFFAIRAILADKNASFKAVIAFSGKKTVDGIEHTEASLNGFA  658
             KGK+KGMVVTQ+IESAIRY+ A+   L     +FK  IAFSG K VDGIE TEA +NGF+
Sbjct  588   KGKGKGMVVTQNIESAIRYYRALTIQLNKMGNPFKVAIAFSGSKEVDGIEYTEADINGFP  647

Query  659   ENETSEKFD-----------------SDEYRILVVANKYLTGFDQPKLSAMYVDKKLQGV  701
             E +T + FD                  D YR+LVVANKYLTGFDQPKL AMYVDKKL +V
Sbjct  648   EGDTKDYFDVNYKRKEPDSPIPKHVDQDAYRLLVVANKYLTGFDQPKLCAMYVDKKLASV  707

Query  702   LAVQALSRLNRSANKLGKKTEDLFILDFFNSVDDIKEAFDPFYTATSLSRATDVNVLHEL  761
             L VQALSRLNRSA K GKKTEDLF+LDFFNSVDDIK AFDPFYT+T+LS ATDVNVLHEL
Sbjct  708   LCVQALSRLNRSAPKYGKKTEDLFVLDFFNSVDDIKTAFDPFYTSTTLSEATDVNVLHEL  767

Query  762   KAQLDDVGVYEWAEVEDFVAKYFSNVDAQLLSPIIDVAAERFSNELDLEDNDKADFKIKA  821
             K ++DD GVYEW EVE+F  ++F   +AQ LSPIID+AA RF++EL+LE++ K DFK+KA
Sbjct  768   KDDMDDTGVYEWFEVEEFNKRFFEGREAQDLSPIIDIAAARFNHELELENEFKVDFKVKA  827

Query  822   KQFVKIYGQMASILPFEVVNWEKLFWFLKFLIPKLIVRDPQGDALDELLQSVDLSTYGLE  881
             KQFVKIYGQ+ASI+P+EVV+WEKLFWFLKFLIPKL V DP+ +ALD LL+SVDLS+YGL+
Sbjct  828   KQFVKIYGQIASIMPYEVVQWEKLFWFLKFLIPKLSVEDPDKEALDSLLDSVDLSSYGLQ  887

Query  882   RTRLGHTITLDDTETEVDPQNPNPRGAHGADEDQDPLEEIIRSFNERNFQGWNATPEEQR  941
             R +L H+I LDD+ETE+DPQNPNPRGA G++ ++DPL+EII+ FNER FQGW+ATPEEQR
Sbjct  888   RVKLNHSIELDDSETELDPQNPNPRGAYGPEAEKDPLDEIIKIFNERWFQGWSATPEEQR  947

Query  942   VKFVSVIKYMQQQPTFETHVLNNPDVQNRELALQKLFNDAVNQQRKLDIEFYKLYTQDPA  1001
             VKFV++   ++++P FE+   NN+D + RELA++K++++ + Q+RK ++E+YKL++QDPA
Sbjct  948   VKFVNIAESIRNHPDFEAKYQNNADPHTRELAFEKMLKEIMLQRRKDELELYKLFAQDPA  1007

Query  1002  FKQAWQDSGRRILGV  1016
             FK +W +S +R++G+
Sbjct  1008  FKASWTQSMQRMVGM  1022

37) Halhy_4891 in NC_015510


> EU272902|14|G13|167832520|ACA01830.1|Vibrio_cholerae_Amazonia_3509|-|13968..17036|-|VPI2_0013c|type 
I restriction enzyme 
HsdR
Length=1022

 Score = 1077 bits (4082),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 693/1035 (67%), Positives = 860/1035 (84%), Gaps = 24/1035 (2%)

Query  1     MPSKTNEQALEAAIEKRLTGSCLEELREQGSSGMEAQEKARRFYRSGNGYYLGFPQDFNA  60
             M SKTNEQALEAAIEK L+G C EEL   G + ++        Y + + Y +G P DF+ 
Sbjct  4     MVSKTNEQALEAAIEKGLAGICKEEL-ALGEAPLN--------Y-NNDLYLIGSPSDFDK  53

Query  61    QWAIDEYRFWDFLENTQAEELAKLQKQA--EWKRKILERLDRMIKKYGILRLFRKGLDVD  118
             Q A+D   FW+FLE+TQA EL KL++ +  +W+RKILER+DRMI + G+LRL++KGLDVD
Sbjct  54    QYALDTRLFWQFLEDTQASELEKLKRTSPHDWQRKILERFDRMIMRHGVLRLLKKGLDVD  113

Query  119   DAHFTLLYPLPLASSSETVKNNFEQNQFSATRQLRYSLANPGEEIDLVLFANGLPFATLE  178
             DA ++L+YP PLASSSE VK++F  N FS TRQ+ YS ANP EEID+VLF NG+P+ TLE
Sbjct  114   DAFLSLMYPAPLASSSEKVKKDFSANLFSVTRQVCYSNANPLEEIDMVLFINGIPLITLE  173

Query  179   LKNHWTGQNAKVHGQNQYRYKRDITQPLLNFGRCIVHFAVDTEEVYMTTKLNGPGTFFLP  238
             LKN WTGQNA  HGQ+QYR  RD  QPLLNF+RC+VH AVDT+EVYMTTKL G  TFFLP
Sbjct  174   LKNPWTGQNAVYHGQKQYRDDRDANQPLLNFARCLVHMAVDTDEVYMTTKLAGKNTFFLP  233

Query  239   LNRGHNFGKGNPPNPQGHKTAYLWEDILTRQSVANIIQHFVRFDGKDNDPLAKKTLYFPR  298
             +N+G NFGKGNP NP+GHKTAYLW++++ ++S+ANIIQHF+R+DG  +  L K+TL+FPR
Sbjct  234   FNKGFNFGKGNPINPHGHKTAYLWQEVFRKESIANIIQHFIRLDGSSKKQLDKRTLFFPR  293

Query  299   YHQLDVVRRLVGHASKHGVGHTYLIQHSAGSGKSNSITWAAYQLIETYPESETLPGSKGQ  358
             YHQ+DVVRRLV+H S +GVG+TYLIQHSAGSGKSNSITWAAYQLIETYP S+ LPGS+G+
Sbjct  294   YHQMDVVRRLVDHCSVNGVGQTYLIQHSAGSGKSNSITWAAYQLIETYPISDDLPGSRGK  353

Query  359   DKPLFDSVIVVTDRRLLDKQLRENIREFSEVKNIVAPAYSSADLKSALEGGkkiiittiq  418
             + PLFDSVIVVTDRRLLDKQLR+NI+EFSEVKNIVAPA+ S++LKSALE GKKIIITTIQ
Sbjct  354   EVPLFDSVIVVTDRRLLDKQLRDNIKEFSEVKNIVAPAFKSSELKSALENGKKIIITTIQ  413

Query  419   kfpfiiDGIADLSYKRFAVIIDEAHSSQSGTAAGKMNQAMGNSASSTEEEDEDPQDKILE  478
             KFP+I+DGIADLS +RFAVIIDEAHSSQ G   +K+N+AMG  +       ED  DK L+
Sbjct  414   KFPYIVDGIADLSDRRFAVIIDEAHSSQDGHNQDKLNEAMGFVS-------EDVLDKALQ  466

Query  479   AMRSRKMRGNASYLAFTATPKNATLERFGTRQPDGKYIPFDLYSMKQAIEEGFILDVLAN  538
             + ++RKMR+NASY+AFTATPKN+TLE+FG RQ+DG Y+PF+LYSMKQAIEEGFILDV+AN
Sbjct  467   SAKNRKMRSNASYFAFTATPKNTTLEKFGQRQADGTYVPFHLYSMKQAIEEGFILDVIAN  526

Query  539   YTTYKSYYEIEKSIEENPLFDTVKAQKKLRNFVEQNQQTIGTKAEIMLDHFITKLVNTKK  598
             YTTYKSYYEIEKSI++NP FD+ KAQK+LR +VE +Q+TI+TKAEIML+HFI  +VN KK
Sbjct  527   YTTYKSYYEIEKSIQDNPEFDSKKAQKRLRAYVEASQETIDTKAEIMLEHFIKHVVNGKK  586

Query  599   LKGKAKAIVATQSIESAINYYFTLQKLLDARGNPFRIAIAFSGAKKIKGIEYTEDSINDF  658
             LKGK+K++V TQ+IESAI YY +L   L+  GNPF++AIAFSG+K + GIEYTE  IN+F
Sbjct  587   LKGKGKGMVVTQNIESAIRYYRALTIQLNKMGNPFKVAIAFSGSKEVDGIEYTEADINGF  646

Query  659   PAALDTAKPTEAGY----ISDKIARYFDLDEYRMLVVANKYLTGFDQPKLSAMYVDKKLQ  714
             P + DT    +  Y        I++  D D YR+LVVANKYLTGFDQPKL AMYVDKKL 
Sbjct  647   PEG-DTKDYFDVNYKRKEPDSPIPKHVDQDAYRLLVVANKYLTGFDQPKLCAMYVDKKLA  705

Query  715   GVLAVQALSRLNRSADKLGKKTEDLFILDFYNSTEDIKKAFDPFYTSTSLSQATDVNVLH  774
             +VL VQALSRLNRSA K GKKTEDLF+LDF+NS +DIK AFDPFYTST+LS+ATDVNVLH
Sbjct  706   SVLCVQALSRLNRSAPKYGKKTEDLFVLDFFNSVDDIKTAFDPFYTSTTLSEATDVNVLH  765

Query  775   ELKAQLDDTGVYEWQEVEAFVAKYFEGVNAQELSPIIDLAADRFNAALELEDQAKADYKI  834
             ELK ++DDTGVYEW EVE F  ++FEG +AQ+LSPIID+AA RFN  LELE++ K D+K+
Sbjct  766   ELKDDMDDTGVYEWFEVEEFNKRFFEGREAQDLSPIIDIAAARFNHELELENEFKVDFKV  825

Query  835   KAKQFVKIYGQMASILPYEILAWEklfwflkflipkliiiDPTQDTLDELLNAVDLSTYG  894
             KAKQFVKIYGQ+ASI+PYE++ WEKLFWFLKFLIPKL + DP +++LD LL++VDLS+YG
Sbjct  826   KAKQFVKIYGQIASIMPYEVVQWEKLFWFLKFLIPKLSVEDPDKEALDSLLDSVDLSSYG  885

Query  895   LERVKLNASIGLDASETELDPQNSNPRAAHSGEADEDPLDLIIKSFNERWFQGWEATPEE  954
             L+RVKLN SI LD SETELDPQN+NPR+A + EA+ DPLD IIK FNERWFQGW ATPEE
Sbjct  886   LQRVKLNHSIELDDSETELDPQNPNPRGAYGPEAEKDPLDEIIKIFNERWFQGWSATPEE  945

Query  955   QRVKFVNLAQRIQEHPDFQEKYADNADPQNREIAFKKIFDDVMGKQRKNELDLYRLLSQD  1014
             QRVKFVN+A+ I++HPDF+ KY +NADP+ RE+AF K++ ++M ++RK+EL+LY+L++QD
Sbjct  946   QRVKFVNIAESIRNHPDFEAKYQNNADPHTRELAFEKMLKEIMLQRRKDELELYKLFAQD  1005

Query  1015  ESFKVAMLDTLKRIL  1029
              +FK +  ++++R++
Sbjct  1006  PAFKASWTQSMQRMV  1020

38) DDD_0824 in NC_020156


> EU272902|14|G13|167832520|ACA01830.1|Vibrio_cholerae_Amazonia_3509|-|13968..17036|-|VPI2_0013c|type 
I restriction enzyme 
HsdR
Length=1022

 Score = 1071 bits (4059),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 678/1036 (66%), Positives = 862/1036 (84%), Gaps = 36/1036 (3%)

Query  1     MHSQTNEQALEAAIEKHLTGTNLEEIKASGESVDGFRESGEIYRTGKGYYIGQASNFNAQ  60
             M S+TNEQALEAAIEK L+G   EE+  +  +++        Y  +  Y IG +S+F+ Q
Sbjct  4     MVSKTNEQALEAAIEKGLAGICKEELALGEAPLN--------YNNDL-YLIGSPSDFDKQ  54

Query  61    FAIDEQFFWDFLESTQKEELEKLQKQG--DWKLKILNRYDRLVkkygilyllkkglQVDD  118
             +A+D ++FW+FLE TQ  ELEKL++ +  DW+ KIL+R+DR++ + G+L LLKKGL+VDD
Sbjct  55    YALDTRLFWQFLEDTQASELEKLKRTSPHDWQRKILERFDRMIMRHGVLRLLKKGLDVDD  114

Query  119   AHFTLFYQLPLASSSQQVKDNFAKNRFSETRQLRYSIDNPREEIDMVLFINGLPVVTMEL  178
             A ++L Y  PLASSS++VK +F+ N FS TRQ+ YS  NP EEIDMVLFING+P++T+EL
Sbjct  115   AFLSLMYPAPLASSSEKVKKDFSANLFSVTRQVCYSNANPLEEIDMVLFINGIPLITLEL  174

Query  179   KNAWTGQNARVHGQHQYKTQRDTKQPLLQFARCVVHFAVDTDEAYMTTKLNGKNTFFLPF  238
             KN+WTGQNA  HGQ QY+ +RD++QPLL+FARC+VH AVDTDE YMTTKL GKNTFFLPF
Sbjct  175   KNPWTGQNAVYHGQKQYRDDRDANQPLLNFARCLVHMAVDTDEVYMTTKLAGKNTFFLPF  234

Query  239   NKGNKHGKGNPELPTGAIGHRTQYLWEEVFTRESLANIIQHFVRLDGKKKDPLQSKTLFF  298
             NKG + GKGNP     + GH+T YLW+EVF +ES+ANIIQHF+RLDG  K  L+ +TLFF
Sbjct  235   NKGFNFGKGNP---INPHGHKTAYLWQEVFRKESIANIIQHFIRLDGSSKKQLDKRTLFF  291

Query  299   PRYHQMDVVRKIIEDASNKGVGQTYLVQHSAGSGKSNSITWAAYQLIETYPVNSNVPGIT  358
             PRYHQMDVVR+++++ S +GVGQTYL+QHSAGSGKSNSITWAAYQLIETYP++ ++PG  
Sbjct  292   PRYHQMDVVRRLVDHCSVNGVGQTYLIQHSAGSGKSNSITWAAYQLIETYPISDDLPGSR  351

Query  359   DVERPLFDSVIVVTDRRLLDKQIRDNIADFSEVKNIIAPAYSSAELRSSLEQGkkiiitt  418
             + E PLFDSVIVVTDRRLLDKQ+RDNI +FSEVKNI+APA+ S+EL+S+LE+GKKIIITT
Sbjct  352   GKEVPLFDSVIVVTDRRLLDKQLRDNIKEFSEVKNIVAPAFKSSELKSALENGKKIIITT  411

Query  419   iqkfpfiiDGIADLSDKRFAVIIDEAHSSQSGSAHDNMNRAMGQQYHEDEAVDAQDKIVQ  478
             IQKFP+I+DGIADLSD+RFAVIIDEAHSSQ G  +D++N AMG  +  ++ +D   K +Q
Sbjct  412   IQKFPYIVDGIADLSDRRFAVIIDEAHSSQDGHNQDKLNEAMG--FVSEDVLD---KALQ  466

Query  479   AMQSRKMRGNASYLAFTATPKPITLEKFGVQQDDGSFKPFHLYSMKQAIEEGFILDVLAN  538
             + ++RKMR+NASY+AFTATPK  TLEKFG +Q DG++ PFHLYSMKQAIEEGFILDV+AN
Sbjct  467   SAKNRKMRSNASYFAFTATPKNTTLEKFGQRQADGTYVPFHLYSMKQAIEEGFILDVIAN  526

Query  539   YTTLKSYYEIEKSIEENPLFDSTKAQKKLRAYVEQHQQTINTKAEIILDHFIPKIVNQKK  598
             YTT KSYYEIEKSI++NP FDS KAQK+LRAYVE  Q+TI+TKAEI+L+HFI  +VN KK
Sbjct  527   YTTYKSYYEIEKSIQDNPEFDSKKAQKRLRAYVEASQETIDTKAEIMLEHFIKHVVNGKK  586

Query  599   LKGKAKAMVVTQSIESAIRYYKALQSILKDKGHPFKIAIAFSGSKEVDGIEYTEAEMNGF  658
             LKGK+K+MVVTQ+IESAIRYY+AL   L+  G+PFK+AIAFSGSKEVDGIEYTEA++NGF
Sbjct  587   LKGKGKGMVVTQNIESAIRYYRALTIQLNKMGNPFKVAIAFSGSKEVDGIEYTEADINGF  646

Query  659   AEKDTR----IKF-------------DEDEYRILVVANKYLTGFDQPKLCAMYVDKKLQG  701
             +E DT+    +++             D+D YR+LVVANKYLTGFDQPKLCAMYVDKKL +
Sbjct  647   PEGDTKDYFDVNYKRKEPDSPIPKHVDQDAYRLLVVANKYLTGFDQPKLCAMYVDKKLAS  706

Query  702   VLAVQALSRLNRAATKLGKKTEDVFVLDFFNSSADIKASFDPFYTATSLSEATDVNVLHE  761
             VL VQALSRLNR+A K GKKTED+FVLDFFNS  DIK++FDPFYT+T+LSEATDVNVLHE
Sbjct  707   VLCVQALSRLNRSAPKYGKKTEDLFVLDFFNSVDDIKTAFDPFYTSTTLSEATDVNVLHE  766

Query  762   LKEVLDDVGVYEWNEVEDFNTKFFNKEDAQVLSPIIERAAERFIHELELEdddkadfkik  821
             LK+ +DD GVYEW EVE+FN +FF+  +AQ LSPII+ AA RF HELELE++ K DFK+K
Sbjct  767   LKDDMDDTGVYEWFEVEEFNKRFFEGREAQDLSPIIDIAAARFNHELELENEFKVDFKVK  826

Query  822   akQFVKIYGQMASIMPFEIVVWEKLYWFLKFLIPKLPVKPGDVDGLDELLESVDLSTYGL  881
             AKQFVKIYGQ+ASIMP+E+V WEKL+WFLKFLIPKL+V   D ++LD LL+SVDLS+YGL
Sbjct  827   AKQFVKIYGQIASIMPYEVVQWEKLFWFLKFLIPKLSVEDPDKEALDSLLDSVDLSSYGL  886

Query  882   ERVRLNEKIGLEDSDSTLDPQNPNPRGAHGSDEDKDPLDLIIQSFNERWFQSWEVTPEDQ  941
             +RV+LN+ I L+DS++ LDPQNPNPRGA G++ +KDPLD II+ FNERWFQ+W  TPE+Q
Sbjct  887   QRVKLNHSIELDDSETELDPQNPNPRGAYGPEAEKDPLDEIIKIFNERWFQGWSATPEEQ  946

Query  942   RVKFISLTKSIKAHPDFESKYLNNSDEQNKSIAFEKIMNDVMSKQRKQELDLYRLYAKDD  1001
             RVKF++++ SI+ HPDFE+KY NN+D + + +AFEK+++++M ++RK+EL+LY+L+A+D 
Sbjct  947   RVKFVNIAESIRNHPDFEAKYQNNADPHTRELAFEKMLKEIMLQRRKDELELYKLFAQDP  1006

Query  1002  AFKIALFDTMRRMASV  1017
             AFK +  ++M+RM ++
Sbjct  1007  AFKASWTQSMQRMVGM  1022

39) hsdR in NC_008255


> EU272902|14|G13|167832520|ACA01830.1|Vibrio_cholerae_Amazonia_3509|-|13968..17036|-|VPI2_0013c|type 
I restriction enzyme 
HsdR
Length=1022

 Score = 1068 bits (4050),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 660/1038 (64%), Positives = 832/1038 (81%), Gaps = 27/1038 (2%)

Query  1     MPSQTNEQALESSIEKCLTGTSLEQLKEQKVSLHIANERRELYRAGNGYYIGSPEDFNAQ  60
             M S+TNEQALE++IEK L+G   E+L     +L+  N+          Y IGSP DF+ Q
Sbjct  4     MVSKTNEQALEAAIEKGLAGICKEELALGEAPLNYNNDL---------YLIGSPSDFDKQ  54

Query  61    FALDEKRFWDFLETTQQEELSKLQKQS--DWKLKIIERLNYTVKKYGILRLFRKGLDIDD  118
             +ALD + FW+FLE TQ  EL KL++ S  DW+ KI+ER++  + + G+LRL++KGLD+DD
Sbjct  55    YALDTRLFWQFLEDTQASELEKLKRTSPHDWQRKILERFDRMIMRHGVLRLLKKGLDVDD  114

Query  119   AHFTLLYPLPLASSSETVRTNFESNQFSVTRQLRYSLINTKEEIDMVLFVNGLPFATMEL  178
             A ++L+YP PLASSSE V+ +F +N FSVTRQ+ YS  N  EEIDMVLF+NG+P+ T+EL
Sbjct  115   AFLSLMYPAPLASSSEKVKKDFSANLFSVTRQVCYSNANPLEEIDMVLFINGIPLITLEL  174

Query  179   KNHWTGQNAKVHGQNQYKTKRDINQPLLNFGRCIVHFAVDTDEAYMTTRLNGNDTFFLPF  238
             KN WTGQNA  HGQ+QY+  RD NQPLLNF+RC+VH AVDTDE YMTT+L G++TFFLPF
Sbjct  175   KNPWTGQNAVYHGQKQYRDDRDANQPLLNFARCLVHMAVDTDEVYMTTKLAGKNTFFLPF  234

Query  239   NLGQREPLFGKGNPVNPFGHKTSYMWEEIFTRKSIANIIQHFVRFDGKETDPLSKKTLYF  298
             N G     FGKGNP+NP GHKT+Y+W+E+F + SIANIIQHF+R+DG     L K+TL+F
Sbjct  235   NKGFN---FGKGNPINPHGHKTAYLWQEVFRKESIANIIQHFIRLDGSSKKQLDKRTLFF  291

Query  299   PRYHQLDVVRKLVDDASKKGVGQTYLIQHSAGSGKSNSITWAAYQLIETYPESDNLPGSK  358
             PRYHQ+DVVR+LVD+ S +GVGQTYLIQHSAGSGKSNSITWAAYQLIETYP SD+LPGS+
Sbjct  292   PRYHQMDVVRRLVDHCSVNGVGQTYLIQHSAGSGKSNSITWAAYQLIETYPISDDLPGSR  351

Query  359   GVSNPLFDSVIVVTDRRLLDKQIRENIKEFSEVKNIVAPAYsskelkeslesgkkIIITT  418
             G   PLFDSVIVVTDRRLLDKQ+R+NIKEFSEVKNIVAPA+ S ELK +LE+GKKIIITT
Sbjct  352   GKEVPLFDSVIVVTDRRLLDKQLRDNIKEFSEVKNIVAPAFKSSELKSALENGKKIIITT  411

Query  419   IQKFPFIVDGIADLSDKRFAVIIDEAHSSQSGTSAGTMNQVMGNAAGDATEDEEIDPQDK  478
             IQKFP+IVDGIADLSD+RFAVIIDEAHSSQ G + + +N+ MG  + D          DK
Sbjct  412   IQKFPYIVDGIADLSDRRFAVIIDEAHSSQDGHNQDKLNEAMGFVSEDVL--------DK  463

Query  479   ILEAMRARKMRGNASYLAFTATPKNNTLERFGVKQEDGKYKPFHLYSMKQAIEEGFILDV  538
              L++ + RKMR+NASY+AFTATPKN TLE+FG +Q DG Y PFHLYSMKQAIEEGFILDV
Sbjct  464   ALQSAKNRKMRSNASYFAFTATPKNTTLEKFGQRQADGTYVPFHLYSMKQAIEEGFILDV  523

Query  539   LANYTTYKSYYEIEKSIEDNPLFETVKAQKKLRTYVEQNKQTIATKADIMLDHFMTKLVN  598
             +ANYTTYKSYYEIEKSI+DNP F++ KAQK+LR+YVE +++TI TKA+IML+HF+  +VN
Sbjct  524   IANYTTYKSYYEIEKSIQDNPEFDSKKAQKRLRAYVEASQETIDTKAEIMLEHFIKHVVN  583

Query  599   TKRLKGKAKAMVATQSIESAINYYFALKKLLDEQGNPFKIAIAFSGVKKIKGIEYTEDSL  658
              K+LKGK+K+MV TQ+IESAI YY AL   L+  GNPFK+AIAFSG K + GIEYTE  +
Sbjct  584   GKKLKGKGKGMVVTQNIESAIRYYRALTIQLNKMGNPFKVAIAFSGSKEVDGIEYTEADI  643

Query  659   NDFPAHLDTAKPSDPGY----ISDKIARFVNMDEYRMLVVANKYLTGYDQPKLTAMYVDK  714
             N+FP   DT    D  Y        I++ V+ D YR+LVVANKYLTG+DQPKL AMYVDK
Sbjct  644   NGFPEG-DTKDYFDVNYKRKEPDSPIPKHVDQDAYRLLVVANKYLTGFDQPKLCAMYVDK  702

Query  715   KLQGVIAVQALSRLNRSADKLGKKTEDLFILDFYNTTEDIKKAFDPFYTATSLSKATDIN  774
             KL +V+ VQALSRLNRSA K GKKTEDLF+LDF+N+ +DIK AFDPFYT+T+LS ATD+N
Sbjct  703   KLASVLCVQALSRLNRSAPKYGKKTEDLFVLDFFNSVDDIKTAFDPFYTSTTLSEATDVN  762

Query  775   VLHELKSNLDDTGVYEWSEVEDFVEKYFKGVNAQELSPIVEVAAERFNVTLELddkakad  834
             VLHELK ++DDTGVYEW EVE+F  ++F G +AQ+LSPI+++AA RFN  LEL++  K D
Sbjct  763   VLHELKDDMDDTGVYEWFEVEEFNKRFFEGREAQDLSPIIDIAAARFNHELELENEFKVD  822

Query  835   ykikakHFVKIYGQMASIMHYEVQAWEKLFWFLKFLIPKLIIVDNASDVLDGLLNSVDLS  894
             +K+KAK+FVKIYGQ+ASIM YEV  WEKLFWFLKFLIPKL + D   + LD+LL+SVDLS
Sbjct  823   FKVKAKQFVKIYGQIASIMPYEVVQWEKLFWFLKFLIPKLSVEDPDKEALDSLLDSVDLS  882

Query  895   TYGLERVKLNTTIVLDAAETEVDPQNPNPRGAHGGDSEEDELDLIIKSFNERWFQGWDAT  954
             +YGL+RVKLN +I LD +ETE+DPQNPNPRGA G ++E D LD IIK FNERWFQGW AT
Sbjct  883   SYGLQRVKLNHSIELDDSETELDPQNPNPRGAYGPEAEKDPLDEIIKIFNERWFQGWSAT  942

Query  955   PDQQRAKFVVIAQRMQAHSDYNEKYAENSDIQNRAIAFAKIIDDVMGKQRKTDMDLYRLY  1014
             P++QR KFV IA+ ++ H+D++ KY +N+D + R +AF K++ ++M ++RK +++LY+L+
Sbjct  943   PEEQRVKFVNIAESIRNHPDFEAKYQNNADPHTRELAFEKMLKEIMLQRRKDELELYKLF  1002

Query  1015  SQDEGFKIAMQDTIKRIL  1032
             +QD +FK +  ++++R++
Sbjct  1003  AQDPAFKASWTQSMQRMV  1020

40) SGRA_4128 in NC_016940


> EU272902|14|G13|167832520|ACA01830.1|Vibrio_cholerae_Amazonia_3509|-|13968..17036|-|VPI2_0013c|type 
I restriction enzyme 
HsdR
Length=1022

 Score = 1056 bits (4004),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 640/1036 (62%), Positives = 835/1036 (81%), Gaps = 32/1036 (3%)

Query  1     MPSKTNEQALEAAIEKALTGSNLEELKAQGYAPQQMAEGEIHYRSGNGFYIGDPNDYDAK  60
             M SKTNEQALEAAIEK+L+G   EEL         ++E+ ++Y + + + IG P+D+D +
Sbjct  4     MVSKTNEQALEAAIEKGLAGICKEEL--------ALGEAPLNY-NNDLYLIGSPSDFDKQ  54

Query  61    WAIDKRRFWHFLESSQAEELAKLRKRSDGEL--KILHRLNVLIKKYGVLELLRKGLDVDD  118
              A+D R FW+FLE +QA EL KL++ S  +   KIL+R++ +I + GVL LL+KGLDVDD
Sbjct  55    YALDTRLFWQFLEDTQASELEKLKRTSPHDWQRKILERFDRMIMRHGVLRLLKKGLDVDD  114

Query  119   AHFELLYPLPLASSGKRVRQQFEQNEFSVSRQLRYSLDKPLQEIDMVIFVNGLPIITMEL  178
             A + L+YP PLASS+ +V+++F  N FSV+RQ+ YS  +PL+EIDMV+F+NG+P+IT+EL
Sbjct  115   AFLSLMYPAPLASSSEKVKKDFSANLFSVTRQVCYSNANPLEEIDMVLFINGIPLITLEL  174

Query  179   KNPWTGQNARYHGQKQYREDRDIRQPLLQFGRCLVHFAVDTDEVYMTTRLAGKGTFFLPF  238
             KNPWTGQNA YHGQKQYR+DRD  QPLL+F+RCLVH AVDTDEVYMTT+LAGK TFFLPF
Sbjct  175   KNPWTGQNAVYHGQKQYRDDRDANQPLLNFARCLVHMAVDTDEVYMTTKLAGKNTFFLPF  234

Query  239   NKGNGQSKGNPVNEFGHKTAYLWEQIFKRESLANLIQHFVRFDGKRTTALNKRTLYFPRF  298
             NKG   +KGNP+N  GHKTAYLW+++F++ES+AN+IQHF+R+DG     L+KRTL+FPR+
Sbjct  235   NKGFNFGKGNPINPHGHKTAYLWQEVFRKESIANIIQHFIRLDGSSKKQLDKRTLFFPRY  294

Query  299   HQLDVVRKIVADIEAEGLGKTYLIQHSAGSGKSNSITWAAYQLIETYPKHENVRGFRGME  358
             HQ+DVVR++V +   +G+G+TYLIQHSAGSGKSNSITWAAYQLIETYP  +++ G RG E
Sbjct  295   HQMDVVRRLVDHCSVNGVGQTYLIQHSAGSGKSNSITWAAYQLIETYPISDDLPGSRGKE  354

Query  359   RPLFDSVIVVTDRRLLDKQIRENIKSFSQVKNIVAPAYRSADLKAALELGKKIIITTIQK  418
              PLFDSVIVVTDRRLLDKQ+R+NIK FS+VKNIVAPA++S++LK+ALE GKKIIITTIQK
Sbjct  355   VPLFDSVIVVTDRRLLDKQLRDNIKEFSEVKNIVAPAFKSSELKSALENGKKIIITTIQK  414

Query  419   FPFVLEGISQMNEKQFAVIIDEAHSSQTGTTADKMN--MTFAKTDDSLGDAQDKLFDLMS  476
             FP++++GI+++++++FAVIIDEAHSSQ G   DK+N  M F  ++D L    DK ++   
Sbjct  415   FPYIVDGIADLSDRRFAVIIDEAHSSQDGHNQDKLNEAMGFV-SEDVL----DKALQSAK  469

Query  477   SRKMRQNVSYLAFTATPKNSTLEKFGVRQADGSFKPFHLYSMKQAIEEGFILDVLANYTT  536
             +RKMR N SY+AFTATPKN+TLEKFG RQADG++ PFHLYSMKQAIEEGFILDV+ANYTT
Sbjct  470   NRKMRSNASYFAFTATPKNTTLEKFGQRQADGTYVPFHLYSMKQAIEEGFILDVIANYTT  529

Query  537   YKSYYELQKSIAENPLFDTKKAQKKLRKYVERQERTIATKAEIMLNHFMEQVQAKRKLKG  596
             YKSYYE++KSI +NP FD+KKAQK+LR YVE  + TI TKAEIML+HF+ +V   +KLKG
Sbjct  530   YKSYYEIEKSIQDNPEFDSKKAQKRLRAYVEASQETIDTKAEIMLEHFIKHVVNGKKLKG  589

Query  597   KGKAMVLTQSIEAAILYYQAMQRLLEQKGNPFRILVAFSGKKMLKGIEYTEEQINYLPAE  656
             KGK+MV+TQ+IE+AI YY+A+   L++ GNPF++ +AFSG K + GIEYTE +IN +P  
Sbjct  590   KGKGMVVTQNIESAIRYYRALTIQLNKMGNPFKVAIAFSGSKEVDGIEYTEADINGFPEG  649

Query  657   LDRA------KSSDPDYISDKIARYFDMDEYRILIVANKYLTGFDQPKLCSMYIDKKLQG  710
               +       K  +PD     I++  D D YR+L+VANKYLTGFDQPKLC+MY+DKKL +
Sbjct  650   DTKDYFDVNYKRKEPD---SPIPKHVDQDAYRLLVVANKYLTGFDQPKLCAMYVDKKLAS  706

Query  711   VLAVQALSRLNRSANKLGKKTEDLFVLDFFNSTEDIKKAFDDFYTATSLSEATDVNILHE  770
             VL VQALSRLNRSA K GKKTEDLFVLDFFNS +DIK AFD FYT+T+LSEATDVN+LHE
Sbjct  707   VLCVQALSRLNRSAPKYGKKTEDLFVLDFFNSVDDIKTAFDPFYTSTTLSEATDVNVLHE  766

Query  771   LKDHLEDPGVYELAEVKEFTNLFFDNADAQLLSPIIDQAAHRFNEELELTDEEKADYKIK  830
             LKD+++D GVYE  EV EF + FF+  +AQ LSPIID AA RFN+ELEL +E K D+K+K
Sbjct  767   LKDDMDDTGVYEWFEVEEFNKRFFEGREAQDLSPIIDIAAARFNHELELENEFKVDFKVK  826

Query  831   AKQFVKIYGQLASIMDMDMDYSRLNWEQLFWFLKFLIPKMVIRNKDKDQLDSLLDAVDLS  890
             AKQFVKIYGQ+ASI    M Y  ++WE+LFWFLKFLIPK+ + + DK+ LDSLLD+VDLS
Sbjct  827   AKQFVKIYGQIASI----MPYEVVQWEKLFWFLKFLIPKLSVEDPDKEALDSLLDSVDLS  882

Query  891   TYGIERVKLNHKIELDAEETSLKPQNANPRGAHeeeekdtl-eeILRMFNERWFKDWGAT  949
             +YG++RVKLNH IELD  ET L PQN+NPRGA   E      +EI+++FNERWF++W+AT
Sbjct  883   SYGLQRVKLNHSIELDDSETELDPQNPNPRGAYGPEAEKDPLDEIIKIFNERWFQGWSAT  942

Query  950   PEEQRIRFASFGEGILNHPDYKDKVMENPDAQNRDMAFDKIMKEVMTHHRKLDIQLYRKF  1009
             PEEQR++F +++E+I NHPD+  K  +N+D++ R++AF+K++KE+M ++RK +++LY+ F
Sbjct  943   PEEQRVKFVNIAESIRNHPDFEAKYQNNADPHTRELAFEKMLKEIMLQRRKDELELYKLF  1002

Query  1010  VQDEGFAQAIIDGLKR  1025
              QD +F  +  ++++R
Sbjct  1003  AQDPAFKASWTQSMQR  1018

41) ZPR_4127 in NC_014041


> EU272902|14|G13|167832520|ACA01830.1|Vibrio_cholerae_Amazonia_3509|-|13968..17036|-|VPI2_0013c|type 
I restriction enzyme 
HsdR
Length=1022

 Score = 1009 bits (3825),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 634/1032 (62%), Positives = 824/1032 (80%), Gaps = 20/1032 (1%)

Query  1     MNNQTNEQALEAAIQKCLTGVSLETLKEEGTSVAEANAVYRTRNGYYNGDRSHFDSKYAL  60
             M ++TNEQALEAAI+K L+G+  E L     +++EA   Y   + Y  G  S+FD +YAL
Sbjct  4     MVSKTNEQALEAAIEKGLAGICKEEL-----ALGEAPLNYNN-DLYLIGSPSDFDKQYAL  57

Query  61    DTERFWDFLESTQEEELNKLKRS--NDWKLKILQRLDRIVKKQGVLHVLKKGLGVDDAHF  118
             DT  FW+FLE TQ  EL+KLKR+  +DW+ KIL+R+DR++ ++GVL++LKKGL+VDDA +
Sbjct  58    DTRLFWQFLEDTQASELEKLKRTSPHDWQRKILERFDRMIMRHGVLRLLKKGLDVDDAFL  117

Query  119   TLLFPLPLGSSSARVAKDFDSNQFSVTRQVPYSESNPREEIDMVIFVNGLPLITLELKNQ  178
             +L++P PL+SSS +V KDF +N FSVTRQV YS++NP EEIDMV+F+NG+PLITLELKN 
Sbjct  118   SLMYPAPLASSSEKVKKDFSANLFSVTRQVCYSNANPLEEIDMVLFINGIPLITLELKNP  177

Query  179   WTGQNARLHGQNQYRKQRDPKEPLLNFGRCLVHMTADTDEVFMTTKLNSTDTFFLPFNQG  238
             WTGQNA  HGQ+QYR +RD+++PLLNF+RCLVHM+ DTDEV+MTTKL + +TFFLPFN+G
Sbjct  178   WTGQNAVYHGQKQYRDDRDANQPLLNFARCLVHMAVDTDEVYMTTKLAGKNTFFLPFNKG  237

Query  239   YENGKGNPPNPFGHKTAYLWEEVFKPKSIANIIQHFVRLDGKSKDPINKRTLFFPRYHQM  298
             ++ GKGNP NP GHKTAYLW+EVF+  SIANIIQHF+RLDG SK  ++KRTLFFPRYHQM
Sbjct  238   FNFGKGNPINPHGHKTAYLWQEVFRKESIANIIQHFIRLDGSSKKQLDKRTLFFPRYHQM  297

Query  299   RVVRKIMAHVSENGTGFRYLIQHSAGSGKSNSITWAAYQLIEAYPENEQAAGKKAIDKPI  358
              VVR+++ H S NG G  YLIQHSAGSGKSNSITWAAYQLIE+YP +++ +G ++ + P+
Sbjct  298   DVVRRLVDHCSVNGVGQTYLIQHSAGSGKSNSITWAAYQLIETYPISDDLPGSRGKEVPL  357

Query  359   FDSVIVVTDRRLLDRQIRENIRSFSEVKNIVAPAYSSRGLKDSLEQGkkiiittiQKFPF  418
             FDSVIVVTDRRLLD+Q+R+NI+ FSEVKNIVAPA+ S  LK +LE+GKKIIITTIQKFP+
Sbjct  358   FDSVIVVTDRRLLDKQLRDNIKEFSEVKNIVAPAFKSSELKSALENGKKIIITTIQKFPY  417

Query  419   IVEGISDLSDKRFAVIIDEAHSSQSGTTADNLNRAIGQESTEAEAEDVQDKIAQVMQSRK  478
             IV+GI+DLSD+RFAVIIDEAHSSQ G   D+LN A+G       +EDV DK  Q  ++RK
Sbjct  418   IVDGIADLSDRRFAVIIDEAHSSQDGHNQDKLNEAMG-----FVSEDVLDKALQSAKNRK  472

Query  479   MQTNASYLAFTATPKNSTLEKFGMPQEDGSFEPFDLYAMKQAIEEGFILDVLNNYTTFKS  538
             M++NASY+AFTATPKN+TLEKFG  Q DG++ PF+LY+MKQAIEEGFILDV+ NYTT+KS
Sbjct  473   MRSNASYFAFTATPKNTTLEKFGQRQADGTYVPFHLYSMKQAIEEGFILDVIANYTTYKS  532

Query  539   YYRLTKSAEENPIFDTKKAQKKLKAFVEKDQQTIDTKAEVMLDHFTKHFVQkkklkgkak  598
             YY + KS ++NP FD+KKAQK+L+A+VE  Q+TIDTKAE+ML+HF KH V+ KKLKGK+K
Sbjct  533   YYEIEKSIQDNPEFDSKKAQKRLRAYVEASQETIDTKAEIMLEHFIKHVVNGKKLKGKGK  592

Query  599   aMFVTQSIESAVRYFKAIQRLLEERGNPFGAICAFSGEKEVDGISLTEESVNNLPAHLDT  658
             +M VTQ+IESA+RY++A+   L+  GNPF    AFSG KEVDGI  TE  +N +P   DT
Sbjct  593   GMVVTQNIESAIRYYRALTIQLNKMGNPFKVAIAFSGSKEVDGIEYTEADINGFPEG-DT  651

Query  659   AKSSDPDY----IQDKIARYFDMDHYRILVVANKYLTGFDQPKLCAMYVDKKLQGVLAVQ  714
                 D +Y     +  I++  D D YR+LVVANKYLTGFDQPKLCAMYVDKKL +VL VQ
Sbjct  652   KDYFDVNYKRKEPDSPIPKHVDQDAYRLLVVANKYLTGFDQPKLCAMYVDKKLASVLCVQ  711

Query  715   ALSRLNRSAPKLGKKTEDIFVLDFFNDKEDIKKAFDPYYTVATLSSATDVNVLHDAKMIL  774
             ALSRLNRSAPK GKKTED+FVLDFFN  +DIK AFDP+YT +TLS ATDVNVLH+ K  +
Sbjct  712   ALSRLNRSAPKYGKKTEDLFVLDFFNSVDDIKTAFDPFYTSTTLSEATDVNVLHELKDDM  771

Query  775   DEEGVYEWSEVELFNDLFFSNADTETLGAALSKPQARFDVELQLEQKQKADYKIKARQFV  834
             D+ GVYEW EVE FN  FF   +++ L++ +  + ARF+ EL+LE+  K D+K+KA+QFV
Sbjct  772   DDTGVYEWFEVEEFNKRFFEGREAQDLSPIIDIAAARFNHELELENEFKVDFKVKAKQFV  831

Query  835   KIYGQVAALLDFNNPEWEMLYWFLKFLIPKMIvkdpdeddldklldavdlaTYGLEQRDK  894
             KIYGQ+A+++ ++  +WE L+WFLKFLIPK+ V DPD + LD LLD+VDL++YGL QR K
Sbjct  832   KIYGQIASIMPYEVVQWEKLFWFLKFLIPKLSVEDPDKEALDSLLDSVDLSSYGL-QRVK  890

Query  895   IGVKIGLDESDSELDPQNSSIRGAHG-ENEEDELEAIIKTFNERYFHGWDATPEEQRVKM  953
             +   I LD+S++ELDPQN++ RGA G E E D L+ IIK FNER F+GW ATPEEQRVK 
Sbjct  891   LNHSIELDDSETELDPQNPNPRGAYGPEAEKDPLDEIIKIFNERWFQGWSATPEEQRVKF  950

Query  954   LSLQKFVEAHPDFEEKVKQNPDEQNSDIALRRIIQEVLSRQRKNELELYKLHTQDSAFQQ  1013
             +++   +  HPDFE K ++N+D +  ++A+ ++++E++ ++RK+ELELYKL +QD+AF+ 
Sbjct  951   VNIAESIRNHPDFEAKYQNNADPHTRELAFEKMLKEIMLQRRKDELELYKLFAQDPAFKA  1010

Query  1014  AFFDTLKRMVQL  1025
             +  ++++RMV +
Sbjct  1011  SWTQSMQRMVGM  1022

42) Fleli_0174 in NC_018018


> EU272902|14|G13|167832520|ACA01830.1|Vibrio_cholerae_Amazonia_3509|-|13968..17036|-|VPI2_0013c|type 
I restriction enzyme 
HsdR
Length=1022

 Score =  994 bits (3766),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 664/1030 (65%), Positives = 840/1030 (82%), Gaps = 35/1030 (3%)

Query  1     MYSKTNEIALEIAIEKYLVGISSEELKTNETHHTDNLYGGDHFYSGKSIDFNKRYAIDEH  60
             M SKTNE ALE AIEK L GI  EEL   E+      Y  D +  G + DF+K+YA+D +
Sbjct  4     MVSKTNEQALEAAIEKGLAGICKEELALGEAPLN---YNNDLYLIGSPSDFDKQYALDTR  60

Query  61    RFWHFLENTQEEELKKLQRSA--DWKLKIMERYDRTVKKYGLLRVLRKGLDVEDAHFTFF  118
              FW+FLE+TQ  EL KL+R++  DW+ KI+ER+DR + + G+LR+L+KGLDV+DA +++ 
Sbjct  61    LFWQFLEDTQASELEKLKRTSPHDWQRKILERFDRMIMRHGVLRLLKKGLDVDDAFLSLM  120

Query  119   YQYPLVSSSQSVKDNFEKNEFSLTRQLHYNSDKPAESIDIVLFVNGLPISTIELKNPWTG  178
             Y  PL SSS+ VK +F  N FS+TRQ+ Y++ +P E ID+VLF+NG+P+ T+ELKNPWTG
Sbjct  121   YPAPLASSSEKVKKDFSANLFSVTRQVCYSNANPLEEIDMVLFINGIPLITLELKNPWTG  180

Query  179   QTAKVEGIRQYQKDRDTNQPLLNFGRCLVHFTLDTDEAYMTTKLVGEKTFFLPFnkgnnn  238
             Q A  +G +QY+ DRD+NQPLLNF+RCLVH ++DTDE YMTTKL G +TFFLPFNKG N 
Sbjct  181   QNAVYHGQKQYRDDRDANQPLLNFARCLVHMAVDTDEVYMTTKLAGKNTFFLPFNKGFNF  240

Query  239   gkgnpvnpngHKTAYVWEEVYTRKSLANIIQHFVRFDGKSTDALSKRTLFFPRYHQMDVV  298
             GKGNP+NP+GHKTAY+W+EV+ + S+ANIIQHF+R+DG S   L KRTLFFPRYHQMDVV
Sbjct  241   GKGNPINPHGHKTAYLWQEVFRKESIANIIQHFIRLDGSSKKQLDKRTLFFPRYHQMDVV  300

Query  299   RKIVQDTTQKGVGKTYLIQHSAGSGKSNSITWLAYQLIEVYPTE----STNSIERPLFDS  354
             R++V++ + +GVG+TYLIQHSAGSGKSNSITW AYQLIE YP      ++ + E PLFDS
Sbjct  301   RRLVDHCSVNGVGQTYLIQHSAGSGKSNSITWAAYQLIETYPISDDLPGSRGKEVPLFDS  360

Query  355   VIVVTDRRLLDKQLRQNIKEFSEVKNIVAPAFSSKELRESLEQGkkiiittiqkfpfiiD  414
             VIVVTDRRLLDKQLR+NIKEFSEVKNIVAPAF S EL+ +LE+GKKIIITTIQKFP+I+D
Sbjct  361   VIVVTDRRLLDKQLRDNIKEFSEVKNIVAPAFKSSELKSALENGKKIIITTIQKFPYIVD  420

Query  415   GIADLSKSRFAVIIDEAHSSQGGSTAGKMNAAMGsseensnedsetedIQDKIVKAMQAR  474
             GIADLS  RFAVIIDEAHSSQ+G   +K+N AMG           +ED+ DK +++ + R
Sbjct  421   GIADLSDRRFAVIIDEAHSSQDGHNQDKLNEAMG---------FVSEDVLDKALQSAKNR  471

Query  475   KMKGNASYFAFTATPKNTTLEKFGELQTDGSFKPFHLYSMKQAIEEGFILDVIANYTTYQ  534
             KM++NASYFAFTATPKNTTLEKFG+ Q+DG++ PFHLYSMKQAIEEGFILDVIANYTTY+
Sbjct  472   KMRSNASYFAFTATPKNTTLEKFGQRQADGTYVPFHLYSMKQAIEEGFILDVIANYTTYK  531

Query  535   SYYEIQKSIEDNPLFDTKKAQKKLKAFVETDKRTINTKAEVIFEHFMSQVVNRKRLKGKA  594
             SYYEI+KSI+DNP FD+KKAQK+L+A+VE+ + TI+TKAE+++EHF+ +VVN K+LKGK+
Sbjct  532   SYYEIEKSIQDNPEFDSKKAQKRLRAYVEASQETIDTKAEIMLEHFIKHVVNGKKLKGKG  591

Query  595   KGMVITQNIETTVRYYTALKRILEEKGNPFKIVVAFSGKKEVDGIEQTETLLNGFSESDT  654
             KGMV+TQNIE+++RYY AL   L+  GNPFK+ +AFSG KEVDGIE TE+ +NGF+E+DT
Sbjct  592   KGMVVTQNIESAIRYYRALTIQLNKMGNPFKVAIAFSGSKEVDGIEYTEADINGFPEGDT  651

Query  655   RENFDT-----------------DEYRLLVVANKYLTGFDQPKLCVMYVDKKLQGVLAVQ  697
             ++ FD                  D YRLLVVANKYLTGFDQPKLC MYVDKKL +VL VQ
Sbjct  652   KDYFDVNYKRKEPDSPIPKHVDQDAYRLLVVANKYLTGFDQPKLCAMYVDKKLASVLCVQ  711

Query  698   ALSRINRAASKYGKKTEDLFVLDFFNSIVDIKASFDPFYTSTTLSEATDINVLHELKSSL  757
             ALSR+NR+A+KYGKKTEDLFVLDFFNS+ DIK++FDPFYTSTTLSEATD+NVLHELK  +
Sbjct  712   ALSRLNRSAPKYGKKTEDLFVLDFFNSVDDIKTAFDPFYTSTTLSEATDVNVLHELKDDM  771

Query  758   DEVGVYETSEIEEFVEKFFQGKDAQGLSPIIDTAAARFNeeleledkekadFKIKAKQFV  817
             D+ GVYE  E+EEF  +FF+G++AQ+LSPIID AAARFN+ELELE+  K DFK+KAKQFV
Sbjct  772   DDTGVYEWFEVEEFNKRFFEGREAQDLSPIIDIAAARFNHELELENEFKVDFKVKAKQFV  831

Query  818   KVYGQISSIIPYEMVAWEKLFWFLKFlipkliiktkdddiidellesvdlSTYGLERKTL  877
             K+YGQI+SI+PYE+V WEKLFWFLKFLIPKL +   D + +D LL+SVDLS+YGL+R  L
Sbjct  832   KIYGQIASIMPYEVVQWEKLFWFLKFLIPKLSVEDPDKEALDSLLDSVDLSSYGLQRVKL  891

Query  878   SHSIVLDDEESELKPQNANPRGAhdsedehdlldeIINTFNQRWFHGWNVTPEDQRVKFV  937
             +HSI LDD E+EL PQN+NPRGA ++E E D LDEII+ FN+RWF+GW+ TPE+QRVKFV
Sbjct  892   NHSIELDDSETELDPQNPNPRGAYGPEAEKDPLDEIIKIFNERWFQGWSATPEEQRVKFV  951

Query  938   TLSKHVQAHPDFETKVANNKDIQNREIAFQKILEEVMMQQRKKELDLYKLYTQDDSFRQA  997
              ++  ++ HPDFE+K  NN D + RE+AF+K+L E+M+Q+RK EL+LYKL++QD +F+ +
Sbjct  952   NIAESIRNHPDFEAKYQNNADPHTRELAFEKMLKEIMLQRRKDELELYKLFAQDPAFKAS  1011

Query  998   FFDTMKQMMG  1007
               ++M++M+G
Sbjct  1012  WTQSMQRMVG  1021

43) APA42C_43180 in NC_017105


> EU272902|14|G13|167832520|ACA01830.1|Vibrio_cholerae_Amazonia_3509|-|13968..17036|-|VPI2_0013c|type 
I restriction enzyme 
HsdR
Length=1022

 Score =  985 bits (3734),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 602/856 (71%), Positives = 727/856 (85%), Gaps = 20/856 (2%)

Query  1     MDMVLFLNGLPIVTLELKNAWTHQTARYHGQKQYRE-RDANQTLLRFGRVLVHMTADTDE  59
             +DMVLF+NG+P++TLELKN+WT Q A YHGQKQYR+ RDANQ LL F+R LVHM+ DTDE
Sbjct  158   IDMVLFINGIPLITLELKNPWTGQNAVYHGQKQYRDDRDANQPLLNFARCLVHMAVDTDE  217

Query  60    VWMATKLAGASTFFLPFNKGHNEgagnppnpngHKTSYLWEEVLQPQSLAGIIQHFVLLE  119
             V M+TKLAG +TFFLPFNKG N G GNP NP+GHKT+YLW+EV++ +S+A IIQHF+ L+
Sbjct  218   VYMTTKLAGKNTFFLPFNKGFNFGKGNPINPHGHKTAYLWQEVFRKESIANIIQHFIRLD  277

Query  120   GKKTDPLTKKTLIFPRYHQLNVVRKLLSHAAQTGVGHKYLIQHSAGSGKSNSITWAAYQL  179
             G     L K+TL+FPRYHQ++VVR+L+ H +  GVG+ YLIQHSAGSGKSNSITWAAYQL
Sbjct  278   GSSKKQLDKRTLFFPRYHQMDVVRRLVDHCSVNGVGQTYLIQHSAGSGKSNSITWAAYQL  337

Query  180   IETYPAKLDLPGVRALDAPLFDSVIVVTDRRLLDKQLRDNIKDFSEVKNIVAPALKSSDL  239
             IETYP   DLPG R+ + PLFDSVIVVTDRRLLDKQLRDNIK+FSEVKNIVAPA+KSS+L
Sbjct  338   IETYPISDDLPGSRGKEVPLFDSVIVVTDRRLLDKQLRDNIKEFSEVKNIVAPAFKSSEL  397

Query  240   KAALENGKKIIITTIQKFPFIIDGIEDLGDKRFAVIIDEAHSGQSGIASDKMNQAMGGDP  299
             K+ALENGKKIIITTIQKFP+I+DGI DL+D+RFAVIIDEAHS+Q G   DK+N+AMG  +
Sbjct  398   KSALENGKKIIITTIQKFPYIVDGIADLSDRRFAVIIDEAHSSQDGHNQDKLNEAMGFVS  457

Query  300   DEDDAQDKILAAMQARKMRGNASYFAFTATPKPITLEKFGEQQSDGRFRPFHLYSMKQAI  359
             +  D  DK L + + RKMR+NASYFAFTATPK  TLEKFG++Q+DG + PFHLYSMKQAI
Sbjct  458   E--DVLDKALQSAKNRKMRSNASYFAFTATPKNTTLEKFGQRQADGTYVPFHLYSMKQAI  515

Query  360   EEGFILDVLANYTTYKGYYEIQKSIEDNPLFDTSKAQKKLRAYVERSQQTINTKAEIMVE  419
             EEGFILDV+ANYTTYK+YYEI+KSI+DNP FD+ KAQK+LRAYVE SQ+TI+TKAEIM+E
Sbjct  516   EEGFILDVIANYTTYKSYYEIEKSIQDNPEFDSKKAQKRLRAYVEASQETIDTKAEIMLE  575

Query  420   NFIDKVVNPKKLRGKGKGMIVTQNIEVAIRYYKAVQAELAKRGNPFKALIAFSGEKEVDG  479
             +FI  VVN KKL+GKGKGM+VTQNIE AIRYY+A+  +L K GNPFK  IAFSG KEVDG
Sbjct  576   HFIKHVVNGKKLKGKGKGMVVTQNIESAIRYYRALTIQLNKMGNPFKVAIAFSGSKEVDG  635

Query  480   VKYTETEMNGVPEDKTRSEFD-----------------KDEFRLLIVANKYLTGFDQPKL  522
             + YTE+++NG PE+ T+  FD                 +D +RLL+VANKYLTGFDQPKL
Sbjct  636   IEYTEADINGFPEGDTKDYFDVNYKRKEPDSPIPKHVDQDAYRLLVVANKYLTGFDQPKL  695

Query  523   CAMYVDKKLQSVLAVQALSRLNRSSPKLGKRTEDLFVLDFFNSIEDIKAAFDPFFTVTTL  582
             CAMYVDKKL SVL VQALSRLNRS+PK GK+TEDLFVLDFFNS++DIK+AFDPF+T TTL
Sbjct  696   CAMYVDKKLASVLCVQALSRLNRSAPKYGKKTEDLFVLDFFNSVDDIKTAFDPFYTSTTL  755

Query  583   SEATDVNVLHELKAALDDVGVYEWSEVEEFCKRFFDGEDSEKLSPLIDVAAERFNTGLEL  642
             SEATDVNVLHELK  +DD GVYEW EVEEF KRFF+G +++ LSP+ID+AA RFN  LEL
Sbjct  756   SEATDVNVLHELKDDMDDTGVYEWFEVEEFNKRFFEGREAQDLSPIIDIAAARFNHELEL  815

Query  643   EDPEKIDFKIKAKQFVKIYGQMAAIMPFEVEAWEKLFWFLKFLVPKLNIKDPNQdalddl  702
             E+  K+DFK+KAKQFVKIYGQ+A+IMP+EV  WEKLFWFLKFL+PKL++ DP+++ALD L
Sbjct  816   ENEFKVDFKVKAKQFVKIYGQIASIMPYEVVQWEKLFWFLKFLIPKLSVEDPDKEALDSL  875

Query  703   lkavdlSSYGLERTKLNQTIGLDTSEAELDPQNPTPRGYREGEVQEDPLEEIIRSFNERW  762
             L +VDLSSYGL+R KLN++I LD SE+ELDPQNP PRG    E + DPL+EII+ FNERW
Sbjct  876   LDSVDLSSYGLQRVKLNHSIELDDSETELDPQNPNPRGAYGPEAEKDPLDEIIKIFNERW  935

Query  763   FQGWSATPEEQRIKFLNIVESVQAHPDFEKKFDENSDPYSRNLAFEKIMKEVMLKRRKEE  822
             FQGWSATPEEQR+KF+NI ES++ HPDFE K+++N+DP +R+LAFEK++KE+ML+RRK+E
Sbjct  936   FQGWSATPEEQRVKFVNIAESIRNHPDFEAKYQNNADPHTRELAFEKMLKEIMLQRRKDE  995

Query  823   LELYKLHNQDEAFRSA  838
             LELYKL  QD AF+++
Sbjct  996   LELYKLFAQDPAFKAS  1011

44) APA01_43180 in NC_013211


> EU272902|14|G13|167832520|ACA01830.1|Vibrio_cholerae_Amazonia_3509|-|13968..17036|-|VPI2_0013c|type 
I restriction enzyme 
HsdR
Length=1022

 Score =  985 bits (3734),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 602/856 (71%), Positives = 727/856 (85%), Gaps = 20/856 (2%)

Query  1     MDMVLFLNGLPIVTLELKNAWTHQTARYHGQKQYRE-RDANQTLLRFGRVLVHMTADTDE  59
             +DMVLF+NG+P++TLELKN+WT Q A YHGQKQYR+ RDANQ LL F+R LVHM+ DTDE
Sbjct  158   IDMVLFINGIPLITLELKNPWTGQNAVYHGQKQYRDDRDANQPLLNFARCLVHMAVDTDE  217

Query  60    VWMATKLAGASTFFLPFNKGHNEgagnppnpngHKTSYLWEEVLQPQSLAGIIQHFVLLE  119
             V M+TKLAG +TFFLPFNKG N G GNP NP+GHKT+YLW+EV++ +S+A IIQHF+ L+
Sbjct  218   VYMTTKLAGKNTFFLPFNKGFNFGKGNPINPHGHKTAYLWQEVFRKESIANIIQHFIRLD  277

Query  120   GKKTDPLTKKTLIFPRYHQLNVVRKLLSHAAQTGVGHKYLIQHSAGSGKSNSITWAAYQL  179
             G     L K+TL+FPRYHQ++VVR+L+ H +  GVG+ YLIQHSAGSGKSNSITWAAYQL
Sbjct  278   GSSKKQLDKRTLFFPRYHQMDVVRRLVDHCSVNGVGQTYLIQHSAGSGKSNSITWAAYQL  337

Query  180   IETYPAKLDLPGVRALDAPLFDSVIVVTDRRLLDKQLRDNIKDFSEVKNIVAPALKSSDL  239
             IETYP   DLPG R+ + PLFDSVIVVTDRRLLDKQLRDNIK+FSEVKNIVAPA+KSS+L
Sbjct  338   IETYPISDDLPGSRGKEVPLFDSVIVVTDRRLLDKQLRDNIKEFSEVKNIVAPAFKSSEL  397

Query  240   KAALENGKKIIITTIQKFPFIIDGIEDLGDKRFAVIIDEAHSGQSGIASDKMNQAMGGDP  299
             K+ALENGKKIIITTIQKFP+I+DGI DL+D+RFAVIIDEAHS+Q G   DK+N+AMG  +
Sbjct  398   KSALENGKKIIITTIQKFPYIVDGIADLSDRRFAVIIDEAHSSQDGHNQDKLNEAMGFVS  457

Query  300   DEDDAQDKILAAMQARKMRGNASYFAFTATPKPITLEKFGEQQSDGRFRPFHLYSMKQAI  359
             +  D  DK L + + RKMR+NASYFAFTATPK  TLEKFG++Q+DG + PFHLYSMKQAI
Sbjct  458   E--DVLDKALQSAKNRKMRSNASYFAFTATPKNTTLEKFGQRQADGTYVPFHLYSMKQAI  515

Query  360   EEGFILDVLANYTTYKGYYEIQKSIEDNPLFDTSKAQKKLRAYVERSQQTINTKAEIMVE  419
             EEGFILDV+ANYTTYK+YYEI+KSI+DNP FD+ KAQK+LRAYVE SQ+TI+TKAEIM+E
Sbjct  516   EEGFILDVIANYTTYKSYYEIEKSIQDNPEFDSKKAQKRLRAYVEASQETIDTKAEIMLE  575

Query  420   NFIDKVVNPKKLRGKGKGMIVTQNIEVAIRYYKAVQAELAKRGNPFKALIAFSGEKEVDG  479
             +FI  VVN KKL+GKGKGM+VTQNIE AIRYY+A+  +L K GNPFK  IAFSG KEVDG
Sbjct  576   HFIKHVVNGKKLKGKGKGMVVTQNIESAIRYYRALTIQLNKMGNPFKVAIAFSGSKEVDG  635

Query  480   VKYTETEMNGVPEDKTRSEFD-----------------KDEFRLLIVANKYLTGFDQPKL  522
             + YTE+++NG PE+ T+  FD                 +D +RLL+VANKYLTGFDQPKL
Sbjct  636   IEYTEADINGFPEGDTKDYFDVNYKRKEPDSPIPKHVDQDAYRLLVVANKYLTGFDQPKL  695

Query  523   CAMYVDKKLQSVLAVQALSRLNRSSPKLGKRTEDLFVLDFFNSIEDIKAAFDPFFTVTTL  582
             CAMYVDKKL SVL VQALSRLNRS+PK GK+TEDLFVLDFFNS++DIK+AFDPF+T TTL
Sbjct  696   CAMYVDKKLASVLCVQALSRLNRSAPKYGKKTEDLFVLDFFNSVDDIKTAFDPFYTSTTL  755

Query  583   SEATDVNVLHELKAALDDVGVYEWSEVEEFCKRFFDGEDSEKLSPLIDVAAERFNTGLEL  642
             SEATDVNVLHELK  +DD GVYEW EVEEF KRFF+G +++ LSP+ID+AA RFN  LEL
Sbjct  756   SEATDVNVLHELKDDMDDTGVYEWFEVEEFNKRFFEGREAQDLSPIIDIAAARFNHELEL  815

Query  643   EDPEKIDFKIKAKQFVKIYGQMAAIMPFEVEAWEKLFWFLKFLVPKLNIKDPNQdalddl  702
             E+  K+DFK+KAKQFVKIYGQ+A+IMP+EV  WEKLFWFLKFL+PKL++ DP+++ALD L
Sbjct  816   ENEFKVDFKVKAKQFVKIYGQIASIMPYEVVQWEKLFWFLKFLIPKLSVEDPDKEALDSL  875

Query  703   lkavdlSSYGLERTKLNQTIGLDTSEAELDPQNPTPRGYREGEVQEDPLEEIIRSFNERW  762
             L +VDLSSYGL+R KLN++I LD SE+ELDPQNP PRG    E + DPL+EII+ FNERW
Sbjct  876   LDSVDLSSYGLQRVKLNHSIELDDSETELDPQNPNPRGAYGPEAEKDPLDEIIKIFNERW  935

Query  763   FQGWSATPEEQRIKFLNIVESVQAHPDFEKKFDENSDPYSRNLAFEKIMKEVMLKRRKEE  822
             FQGWSATPEEQR+KF+NI ES++ HPDFE K+++N+DP +R+LAFEK++KE+ML+RRK+E
Sbjct  936   FQGWSATPEEQRVKFVNIAESIRNHPDFEAKYQNNADPHTRELAFEKMLKEIMLQRRKDE  995

Query  823   LELYKLHNQDEAFRSA  838
             LELYKL  QD AF+++
Sbjct  996   LELYKLFAQDPAFKAS  1011

45) APA03_43180 in NC_017118


> EU272902|14|G13|167832520|ACA01830.1|Vibrio_cholerae_Amazonia_3509|-|13968..17036|-|VPI2_0013c|type 
I restriction enzyme 
HsdR
Length=1022

 Score =  985 bits (3734),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 602/856 (71%), Positives = 727/856 (85%), Gaps = 20/856 (2%)

Query  1     MDMVLFLNGLPIVTLELKNAWTHQTARYHGQKQYRE-RDANQTLLRFGRVLVHMTADTDE  59
             +DMVLF+NG+P++TLELKN+WT Q A YHGQKQYR+ RDANQ LL F+R LVHM+ DTDE
Sbjct  158   IDMVLFINGIPLITLELKNPWTGQNAVYHGQKQYRDDRDANQPLLNFARCLVHMAVDTDE  217

Query  60    VWMATKLAGASTFFLPFNKGHNEgagnppnpngHKTSYLWEEVLQPQSLAGIIQHFVLLE  119
             V M+TKLAG +TFFLPFNKG N G GNP NP+GHKT+YLW+EV++ +S+A IIQHF+ L+
Sbjct  218   VYMTTKLAGKNTFFLPFNKGFNFGKGNPINPHGHKTAYLWQEVFRKESIANIIQHFIRLD  277

Query  120   GKKTDPLTKKTLIFPRYHQLNVVRKLLSHAAQTGVGHKYLIQHSAGSGKSNSITWAAYQL  179
             G     L K+TL+FPRYHQ++VVR+L+ H +  GVG+ YLIQHSAGSGKSNSITWAAYQL
Sbjct  278   GSSKKQLDKRTLFFPRYHQMDVVRRLVDHCSVNGVGQTYLIQHSAGSGKSNSITWAAYQL  337

Query  180   IETYPAKLDLPGVRALDAPLFDSVIVVTDRRLLDKQLRDNIKDFSEVKNIVAPALKSSDL  239
             IETYP   DLPG R+ + PLFDSVIVVTDRRLLDKQLRDNIK+FSEVKNIVAPA+KSS+L
Sbjct  338   IETYPISDDLPGSRGKEVPLFDSVIVVTDRRLLDKQLRDNIKEFSEVKNIVAPAFKSSEL  397

Query  240   KAALENGKKIIITTIQKFPFIIDGIEDLGDKRFAVIIDEAHSGQSGIASDKMNQAMGGDP  299
             K+ALENGKKIIITTIQKFP+I+DGI DL+D+RFAVIIDEAHS+Q G   DK+N+AMG  +
Sbjct  398   KSALENGKKIIITTIQKFPYIVDGIADLSDRRFAVIIDEAHSSQDGHNQDKLNEAMGFVS  457

Query  300   DEDDAQDKILAAMQARKMRGNASYFAFTATPKPITLEKFGEQQSDGRFRPFHLYSMKQAI  359
             +  D  DK L + + RKMR+NASYFAFTATPK  TLEKFG++Q+DG + PFHLYSMKQAI
Sbjct  458   E--DVLDKALQSAKNRKMRSNASYFAFTATPKNTTLEKFGQRQADGTYVPFHLYSMKQAI  515

Query  360   EEGFILDVLANYTTYKGYYEIQKSIEDNPLFDTSKAQKKLRAYVERSQQTINTKAEIMVE  419
             EEGFILDV+ANYTTYK+YYEI+KSI+DNP FD+ KAQK+LRAYVE SQ+TI+TKAEIM+E
Sbjct  516   EEGFILDVIANYTTYKSYYEIEKSIQDNPEFDSKKAQKRLRAYVEASQETIDTKAEIMLE  575

Query  420   NFIDKVVNPKKLRGKGKGMIVTQNIEVAIRYYKAVQAELAKRGNPFKALIAFSGEKEVDG  479
             +FI  VVN KKL+GKGKGM+VTQNIE AIRYY+A+  +L K GNPFK  IAFSG KEVDG
Sbjct  576   HFIKHVVNGKKLKGKGKGMVVTQNIESAIRYYRALTIQLNKMGNPFKVAIAFSGSKEVDG  635

Query  480   VKYTETEMNGVPEDKTRSEFD-----------------KDEFRLLIVANKYLTGFDQPKL  522
             + YTE+++NG PE+ T+  FD                 +D +RLL+VANKYLTGFDQPKL
Sbjct  636   IEYTEADINGFPEGDTKDYFDVNYKRKEPDSPIPKHVDQDAYRLLVVANKYLTGFDQPKL  695

Query  523   CAMYVDKKLQSVLAVQALSRLNRSSPKLGKRTEDLFVLDFFNSIEDIKAAFDPFFTVTTL  582
             CAMYVDKKL SVL VQALSRLNRS+PK GK+TEDLFVLDFFNS++DIK+AFDPF+T TTL
Sbjct  696   CAMYVDKKLASVLCVQALSRLNRSAPKYGKKTEDLFVLDFFNSVDDIKTAFDPFYTSTTL  755

Query  583   SEATDVNVLHELKAALDDVGVYEWSEVEEFCKRFFDGEDSEKLSPLIDVAAERFNTGLEL  642
             SEATDVNVLHELK  +DD GVYEW EVEEF KRFF+G +++ LSP+ID+AA RFN  LEL
Sbjct  756   SEATDVNVLHELKDDMDDTGVYEWFEVEEFNKRFFEGREAQDLSPIIDIAAARFNHELEL  815

Query  643   EDPEKIDFKIKAKQFVKIYGQMAAIMPFEVEAWEKLFWFLKFLVPKLNIKDPNQdalddl  702
             E+  K+DFK+KAKQFVKIYGQ+A+IMP+EV  WEKLFWFLKFL+PKL++ DP+++ALD L
Sbjct  816   ENEFKVDFKVKAKQFVKIYGQIASIMPYEVVQWEKLFWFLKFLIPKLSVEDPDKEALDSL  875

Query  703   lkavdlSSYGLERTKLNQTIGLDTSEAELDPQNPTPRGYREGEVQEDPLEEIIRSFNERW  762
             L +VDLSSYGL+R KLN++I LD SE+ELDPQNP PRG    E + DPL+EII+ FNERW
Sbjct  876   LDSVDLSSYGLQRVKLNHSIELDDSETELDPQNPNPRGAYGPEAEKDPLDEIIKIFNERW  935

Query  763   FQGWSATPEEQRIKFLNIVESVQAHPDFEKKFDENSDPYSRNLAFEKIMKEVMLKRRKEE  822
             FQGWSATPEEQR+KF+NI ES++ HPDFE K+++N+DP +R+LAFEK++KE+ML+RRK+E
Sbjct  936   FQGWSATPEEQRVKFVNIAESIRNHPDFEAKYQNNADPHTRELAFEKMLKEIMLQRRKDE  995

Query  823   LELYKLHNQDEAFRSA  838
             LELYKL  QD AF+++
Sbjct  996   LELYKLFAQDPAFKAS  1011

46) APA07_43180 in NC_017122


> EU272902|14|G13|167832520|ACA01830.1|Vibrio_cholerae_Amazonia_3509|-|13968..17036|-|VPI2_0013c|type 
I restriction enzyme 
HsdR
Length=1022

 Score =  985 bits (3734),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 602/856 (71%), Positives = 727/856 (85%), Gaps = 20/856 (2%)

Query  1     MDMVLFLNGLPIVTLELKNAWTHQTARYHGQKQYRE-RDANQTLLRFGRVLVHMTADTDE  59
             +DMVLF+NG+P++TLELKN+WT Q A YHGQKQYR+ RDANQ LL F+R LVHM+ DTDE
Sbjct  158   IDMVLFINGIPLITLELKNPWTGQNAVYHGQKQYRDDRDANQPLLNFARCLVHMAVDTDE  217

Query  60    VWMATKLAGASTFFLPFNKGHNEgagnppnpngHKTSYLWEEVLQPQSLAGIIQHFVLLE  119
             V M+TKLAG +TFFLPFNKG N G GNP NP+GHKT+YLW+EV++ +S+A IIQHF+ L+
Sbjct  218   VYMTTKLAGKNTFFLPFNKGFNFGKGNPINPHGHKTAYLWQEVFRKESIANIIQHFIRLD  277

Query  120   GKKTDPLTKKTLIFPRYHQLNVVRKLLSHAAQTGVGHKYLIQHSAGSGKSNSITWAAYQL  179
             G     L K+TL+FPRYHQ++VVR+L+ H +  GVG+ YLIQHSAGSGKSNSITWAAYQL
Sbjct  278   GSSKKQLDKRTLFFPRYHQMDVVRRLVDHCSVNGVGQTYLIQHSAGSGKSNSITWAAYQL  337

Query  180   IETYPAKLDLPGVRALDAPLFDSVIVVTDRRLLDKQLRDNIKDFSEVKNIVAPALKSSDL  239
             IETYP   DLPG R+ + PLFDSVIVVTDRRLLDKQLRDNIK+FSEVKNIVAPA+KSS+L
Sbjct  338   IETYPISDDLPGSRGKEVPLFDSVIVVTDRRLLDKQLRDNIKEFSEVKNIVAPAFKSSEL  397

Query  240   KAALENGKKIIITTIQKFPFIIDGIEDLGDKRFAVIIDEAHSGQSGIASDKMNQAMGGDP  299
             K+ALENGKKIIITTIQKFP+I+DGI DL+D+RFAVIIDEAHS+Q G   DK+N+AMG  +
Sbjct  398   KSALENGKKIIITTIQKFPYIVDGIADLSDRRFAVIIDEAHSSQDGHNQDKLNEAMGFVS  457

Query  300   DEDDAQDKILAAMQARKMRGNASYFAFTATPKPITLEKFGEQQSDGRFRPFHLYSMKQAI  359
             +  D  DK L + + RKMR+NASYFAFTATPK  TLEKFG++Q+DG + PFHLYSMKQAI
Sbjct  458   E--DVLDKALQSAKNRKMRSNASYFAFTATPKNTTLEKFGQRQADGTYVPFHLYSMKQAI  515

Query  360   EEGFILDVLANYTTYKGYYEIQKSIEDNPLFDTSKAQKKLRAYVERSQQTINTKAEIMVE  419
             EEGFILDV+ANYTTYK+YYEI+KSI+DNP FD+ KAQK+LRAYVE SQ+TI+TKAEIM+E
Sbjct  516   EEGFILDVIANYTTYKSYYEIEKSIQDNPEFDSKKAQKRLRAYVEASQETIDTKAEIMLE  575

Query  420   NFIDKVVNPKKLRGKGKGMIVTQNIEVAIRYYKAVQAELAKRGNPFKALIAFSGEKEVDG  479
             +FI  VVN KKL+GKGKGM+VTQNIE AIRYY+A+  +L K GNPFK  IAFSG KEVDG
Sbjct  576   HFIKHVVNGKKLKGKGKGMVVTQNIESAIRYYRALTIQLNKMGNPFKVAIAFSGSKEVDG  635

Query  480   VKYTETEMNGVPEDKTRSEFD-----------------KDEFRLLIVANKYLTGFDQPKL  522
             + YTE+++NG PE+ T+  FD                 +D +RLL+VANKYLTGFDQPKL
Sbjct  636   IEYTEADINGFPEGDTKDYFDVNYKRKEPDSPIPKHVDQDAYRLLVVANKYLTGFDQPKL  695

Query  523   CAMYVDKKLQSVLAVQALSRLNRSSPKLGKRTEDLFVLDFFNSIEDIKAAFDPFFTVTTL  582
             CAMYVDKKL SVL VQALSRLNRS+PK GK+TEDLFVLDFFNS++DIK+AFDPF+T TTL
Sbjct  696   CAMYVDKKLASVLCVQALSRLNRSAPKYGKKTEDLFVLDFFNSVDDIKTAFDPFYTSTTL  755

Query  583   SEATDVNVLHELKAALDDVGVYEWSEVEEFCKRFFDGEDSEKLSPLIDVAAERFNTGLEL  642
             SEATDVNVLHELK  +DD GVYEW EVEEF KRFF+G +++ LSP+ID+AA RFN  LEL
Sbjct  756   SEATDVNVLHELKDDMDDTGVYEWFEVEEFNKRFFEGREAQDLSPIIDIAAARFNHELEL  815

Query  643   EDPEKIDFKIKAKQFVKIYGQMAAIMPFEVEAWEKLFWFLKFLVPKLNIKDPNQdalddl  702
             E+  K+DFK+KAKQFVKIYGQ+A+IMP+EV  WEKLFWFLKFL+PKL++ DP+++ALD L
Sbjct  816   ENEFKVDFKVKAKQFVKIYGQIASIMPYEVVQWEKLFWFLKFLIPKLSVEDPDKEALDSL  875

Query  703   lkavdlSSYGLERTKLNQTIGLDTSEAELDPQNPTPRGYREGEVQEDPLEEIIRSFNERW  762
             L +VDLSSYGL+R KLN++I LD SE+ELDPQNP PRG    E + DPL+EII+ FNERW
Sbjct  876   LDSVDLSSYGLQRVKLNHSIELDDSETELDPQNPNPRGAYGPEAEKDPLDEIIKIFNERW  935

Query  763   FQGWSATPEEQRIKFLNIVESVQAHPDFEKKFDENSDPYSRNLAFEKIMKEVMLKRRKEE  822
             FQGWSATPEEQR+KF+NI ES++ HPDFE K+++N+DP +R+LAFEK++KE+ML+RRK+E
Sbjct  936   FQGWSATPEEQRVKFVNIAESIRNHPDFEAKYQNNADPHTRELAFEKMLKEIMLQRRKDE  995

Query  823   LELYKLHNQDEAFRSA  838
             LELYKL  QD AF+++
Sbjct  996   LELYKLFAQDPAFKAS  1011

47) APA12_43180 in NC_017113


> EU272902|14|G13|167832520|ACA01830.1|Vibrio_cholerae_Amazonia_3509|-|13968..17036|-|VPI2_0013c|type 
I restriction enzyme 
HsdR
Length=1022

 Score =  985 bits (3734),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 602/856 (71%), Positives = 727/856 (85%), Gaps = 20/856 (2%)

Query  1     MDMVLFLNGLPIVTLELKNAWTHQTARYHGQKQYRE-RDANQTLLRFGRVLVHMTADTDE  59
             +DMVLF+NG+P++TLELKN+WT Q A YHGQKQYR+ RDANQ LL F+R LVHM+ DTDE
Sbjct  158   IDMVLFINGIPLITLELKNPWTGQNAVYHGQKQYRDDRDANQPLLNFARCLVHMAVDTDE  217

Query  60    VWMATKLAGASTFFLPFNKGHNEgagnppnpngHKTSYLWEEVLQPQSLAGIIQHFVLLE  119
             V M+TKLAG +TFFLPFNKG N G GNP NP+GHKT+YLW+EV++ +S+A IIQHF+ L+
Sbjct  218   VYMTTKLAGKNTFFLPFNKGFNFGKGNPINPHGHKTAYLWQEVFRKESIANIIQHFIRLD  277

Query  120   GKKTDPLTKKTLIFPRYHQLNVVRKLLSHAAQTGVGHKYLIQHSAGSGKSNSITWAAYQL  179
             G     L K+TL+FPRYHQ++VVR+L+ H +  GVG+ YLIQHSAGSGKSNSITWAAYQL
Sbjct  278   GSSKKQLDKRTLFFPRYHQMDVVRRLVDHCSVNGVGQTYLIQHSAGSGKSNSITWAAYQL  337

Query  180   IETYPAKLDLPGVRALDAPLFDSVIVVTDRRLLDKQLRDNIKDFSEVKNIVAPALKSSDL  239
             IETYP   DLPG R+ + PLFDSVIVVTDRRLLDKQLRDNIK+FSEVKNIVAPA+KSS+L
Sbjct  338   IETYPISDDLPGSRGKEVPLFDSVIVVTDRRLLDKQLRDNIKEFSEVKNIVAPAFKSSEL  397

Query  240   KAALENGKKIIITTIQKFPFIIDGIEDLGDKRFAVIIDEAHSGQSGIASDKMNQAMGGDP  299
             K+ALENGKKIIITTIQKFP+I+DGI DL+D+RFAVIIDEAHS+Q G   DK+N+AMG  +
Sbjct  398   KSALENGKKIIITTIQKFPYIVDGIADLSDRRFAVIIDEAHSSQDGHNQDKLNEAMGFVS  457

Query  300   DEDDAQDKILAAMQARKMRGNASYFAFTATPKPITLEKFGEQQSDGRFRPFHLYSMKQAI  359
             +  D  DK L + + RKMR+NASYFAFTATPK  TLEKFG++Q+DG + PFHLYSMKQAI
Sbjct  458   E--DVLDKALQSAKNRKMRSNASYFAFTATPKNTTLEKFGQRQADGTYVPFHLYSMKQAI  515

Query  360   EEGFILDVLANYTTYKGYYEIQKSIEDNPLFDTSKAQKKLRAYVERSQQTINTKAEIMVE  419
             EEGFILDV+ANYTTYK+YYEI+KSI+DNP FD+ KAQK+LRAYVE SQ+TI+TKAEIM+E
Sbjct  516   EEGFILDVIANYTTYKSYYEIEKSIQDNPEFDSKKAQKRLRAYVEASQETIDTKAEIMLE  575

Query  420   NFIDKVVNPKKLRGKGKGMIVTQNIEVAIRYYKAVQAELAKRGNPFKALIAFSGEKEVDG  479
             +FI  VVN KKL+GKGKGM+VTQNIE AIRYY+A+  +L K GNPFK  IAFSG KEVDG
Sbjct  576   HFIKHVVNGKKLKGKGKGMVVTQNIESAIRYYRALTIQLNKMGNPFKVAIAFSGSKEVDG  635

Query  480   VKYTETEMNGVPEDKTRSEFD-----------------KDEFRLLIVANKYLTGFDQPKL  522
             + YTE+++NG PE+ T+  FD                 +D +RLL+VANKYLTGFDQPKL
Sbjct  636   IEYTEADINGFPEGDTKDYFDVNYKRKEPDSPIPKHVDQDAYRLLVVANKYLTGFDQPKL  695

Query  523   CAMYVDKKLQSVLAVQALSRLNRSSPKLGKRTEDLFVLDFFNSIEDIKAAFDPFFTVTTL  582
             CAMYVDKKL SVL VQALSRLNRS+PK GK+TEDLFVLDFFNS++DIK+AFDPF+T TTL
Sbjct  696   CAMYVDKKLASVLCVQALSRLNRSAPKYGKKTEDLFVLDFFNSVDDIKTAFDPFYTSTTL  755

Query  583   SEATDVNVLHELKAALDDVGVYEWSEVEEFCKRFFDGEDSEKLSPLIDVAAERFNTGLEL  642
             SEATDVNVLHELK  +DD GVYEW EVEEF KRFF+G +++ LSP+ID+AA RFN  LEL
Sbjct  756   SEATDVNVLHELKDDMDDTGVYEWFEVEEFNKRFFEGREAQDLSPIIDIAAARFNHELEL  815

Query  643   EDPEKIDFKIKAKQFVKIYGQMAAIMPFEVEAWEKLFWFLKFLVPKLNIKDPNQdalddl  702
             E+  K+DFK+KAKQFVKIYGQ+A+IMP+EV  WEKLFWFLKFL+PKL++ DP+++ALD L
Sbjct  816   ENEFKVDFKVKAKQFVKIYGQIASIMPYEVVQWEKLFWFLKFLIPKLSVEDPDKEALDSL  875

Query  703   lkavdlSSYGLERTKLNQTIGLDTSEAELDPQNPTPRGYREGEVQEDPLEEIIRSFNERW  762
             L +VDLSSYGL+R KLN++I LD SE+ELDPQNP PRG    E + DPL+EII+ FNERW
Sbjct  876   LDSVDLSSYGLQRVKLNHSIELDDSETELDPQNPNPRGAYGPEAEKDPLDEIIKIFNERW  935

Query  763   FQGWSATPEEQRIKFLNIVESVQAHPDFEKKFDENSDPYSRNLAFEKIMKEVMLKRRKEE  822
             FQGWSATPEEQR+KF+NI ES++ HPDFE K+++N+DP +R+LAFEK++KE+ML+RRK+E
Sbjct  936   FQGWSATPEEQRVKFVNIAESIRNHPDFEAKYQNNADPHTRELAFEKMLKEIMLQRRKDE  995

Query  823   LELYKLHNQDEAFRSA  838
             LELYKL  QD AF+++
Sbjct  996   LELYKLFAQDPAFKAS  1011

48) APA22_43180 in NC_017126


> EU272902|14|G13|167832520|ACA01830.1|Vibrio_cholerae_Amazonia_3509|-|13968..17036|-|VPI2_0013c|type 
I restriction enzyme 
HsdR
Length=1022

 Score =  985 bits (3734),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 602/856 (71%), Positives = 727/856 (85%), Gaps = 20/856 (2%)

Query  1     MDMVLFLNGLPIVTLELKNAWTHQTARYHGQKQYRE-RDANQTLLRFGRVLVHMTADTDE  59
             +DMVLF+NG+P++TLELKN+WT Q A YHGQKQYR+ RDANQ LL F+R LVHM+ DTDE
Sbjct  158   IDMVLFINGIPLITLELKNPWTGQNAVYHGQKQYRDDRDANQPLLNFARCLVHMAVDTDE  217

Query  60    VWMATKLAGASTFFLPFNKGHNEgagnppnpngHKTSYLWEEVLQPQSLAGIIQHFVLLE  119
             V M+TKLAG +TFFLPFNKG N G GNP NP+GHKT+YLW+EV++ +S+A IIQHF+ L+
Sbjct  218   VYMTTKLAGKNTFFLPFNKGFNFGKGNPINPHGHKTAYLWQEVFRKESIANIIQHFIRLD  277

Query  120   GKKTDPLTKKTLIFPRYHQLNVVRKLLSHAAQTGVGHKYLIQHSAGSGKSNSITWAAYQL  179
             G     L K+TL+FPRYHQ++VVR+L+ H +  GVG+ YLIQHSAGSGKSNSITWAAYQL
Sbjct  278   GSSKKQLDKRTLFFPRYHQMDVVRRLVDHCSVNGVGQTYLIQHSAGSGKSNSITWAAYQL  337

Query  180   IETYPAKLDLPGVRALDAPLFDSVIVVTDRRLLDKQLRDNIKDFSEVKNIVAPALKSSDL  239
             IETYP   DLPG R+ + PLFDSVIVVTDRRLLDKQLRDNIK+FSEVKNIVAPA+KSS+L
Sbjct  338   IETYPISDDLPGSRGKEVPLFDSVIVVTDRRLLDKQLRDNIKEFSEVKNIVAPAFKSSEL  397

Query  240   KAALENGKKIIITTIQKFPFIIDGIEDLGDKRFAVIIDEAHSGQSGIASDKMNQAMGGDP  299
             K+ALENGKKIIITTIQKFP+I+DGI DL+D+RFAVIIDEAHS+Q G   DK+N+AMG  +
Sbjct  398   KSALENGKKIIITTIQKFPYIVDGIADLSDRRFAVIIDEAHSSQDGHNQDKLNEAMGFVS  457

Query  300   DEDDAQDKILAAMQARKMRGNASYFAFTATPKPITLEKFGEQQSDGRFRPFHLYSMKQAI  359
             +  D  DK L + + RKMR+NASYFAFTATPK  TLEKFG++Q+DG + PFHLYSMKQAI
Sbjct  458   E--DVLDKALQSAKNRKMRSNASYFAFTATPKNTTLEKFGQRQADGTYVPFHLYSMKQAI  515

Query  360   EEGFILDVLANYTTYKGYYEIQKSIEDNPLFDTSKAQKKLRAYVERSQQTINTKAEIMVE  419
             EEGFILDV+ANYTTYK+YYEI+KSI+DNP FD+ KAQK+LRAYVE SQ+TI+TKAEIM+E
Sbjct  516   EEGFILDVIANYTTYKSYYEIEKSIQDNPEFDSKKAQKRLRAYVEASQETIDTKAEIMLE  575

Query  420   NFIDKVVNPKKLRGKGKGMIVTQNIEVAIRYYKAVQAELAKRGNPFKALIAFSGEKEVDG  479
             +FI  VVN KKL+GKGKGM+VTQNIE AIRYY+A+  +L K GNPFK  IAFSG KEVDG
Sbjct  576   HFIKHVVNGKKLKGKGKGMVVTQNIESAIRYYRALTIQLNKMGNPFKVAIAFSGSKEVDG  635

Query  480   VKYTETEMNGVPEDKTRSEFD-----------------KDEFRLLIVANKYLTGFDQPKL  522
             + YTE+++NG PE+ T+  FD                 +D +RLL+VANKYLTGFDQPKL
Sbjct  636   IEYTEADINGFPEGDTKDYFDVNYKRKEPDSPIPKHVDQDAYRLLVVANKYLTGFDQPKL  695

Query  523   CAMYVDKKLQSVLAVQALSRLNRSSPKLGKRTEDLFVLDFFNSIEDIKAAFDPFFTVTTL  582
             CAMYVDKKL SVL VQALSRLNRS+PK GK+TEDLFVLDFFNS++DIK+AFDPF+T TTL
Sbjct  696   CAMYVDKKLASVLCVQALSRLNRSAPKYGKKTEDLFVLDFFNSVDDIKTAFDPFYTSTTL  755

Query  583   SEATDVNVLHELKAALDDVGVYEWSEVEEFCKRFFDGEDSEKLSPLIDVAAERFNTGLEL  642
             SEATDVNVLHELK  +DD GVYEW EVEEF KRFF+G +++ LSP+ID+AA RFN  LEL
Sbjct  756   SEATDVNVLHELKDDMDDTGVYEWFEVEEFNKRFFEGREAQDLSPIIDIAAARFNHELEL  815

Query  643   EDPEKIDFKIKAKQFVKIYGQMAAIMPFEVEAWEKLFWFLKFLVPKLNIKDPNQdalddl  702
             E+  K+DFK+KAKQFVKIYGQ+A+IMP+EV  WEKLFWFLKFL+PKL++ DP+++ALD L
Sbjct  816   ENEFKVDFKVKAKQFVKIYGQIASIMPYEVVQWEKLFWFLKFLIPKLSVEDPDKEALDSL  875

Query  703   lkavdlSSYGLERTKLNQTIGLDTSEAELDPQNPTPRGYREGEVQEDPLEEIIRSFNERW  762
             L +VDLSSYGL+R KLN++I LD SE+ELDPQNP PRG    E + DPL+EII+ FNERW
Sbjct  876   LDSVDLSSYGLQRVKLNHSIELDDSETELDPQNPNPRGAYGPEAEKDPLDEIIKIFNERW  935

Query  763   FQGWSATPEEQRIKFLNIVESVQAHPDFEKKFDENSDPYSRNLAFEKIMKEVMLKRRKEE  822
             FQGWSATPEEQR+KF+NI ES++ HPDFE K+++N+DP +R+LAFEK++KE+ML+RRK+E
Sbjct  936   FQGWSATPEEQRVKFVNIAESIRNHPDFEAKYQNNADPHTRELAFEKMLKEIMLQRRKDE  995

Query  823   LELYKLHNQDEAFRSA  838
             LELYKL  QD AF+++
Sbjct  996   LELYKLFAQDPAFKAS  1011

49) APA26_43180 in NC_017131


> EU272902|14|G13|167832520|ACA01830.1|Vibrio_cholerae_Amazonia_3509|-|13968..17036|-|VPI2_0013c|type 
I restriction enzyme 
HsdR
Length=1022

 Score =  985 bits (3734),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 602/856 (71%), Positives = 727/856 (85%), Gaps = 20/856 (2%)

Query  1     MDMVLFLNGLPIVTLELKNAWTHQTARYHGQKQYRE-RDANQTLLRFGRVLVHMTADTDE  59
             +DMVLF+NG+P++TLELKN+WT Q A YHGQKQYR+ RDANQ LL F+R LVHM+ DTDE
Sbjct  158   IDMVLFINGIPLITLELKNPWTGQNAVYHGQKQYRDDRDANQPLLNFARCLVHMAVDTDE  217

Query  60    VWMATKLAGASTFFLPFNKGHNEgagnppnpngHKTSYLWEEVLQPQSLAGIIQHFVLLE  119
             V M+TKLAG +TFFLPFNKG N G GNP NP+GHKT+YLW+EV++ +S+A IIQHF+ L+
Sbjct  218   VYMTTKLAGKNTFFLPFNKGFNFGKGNPINPHGHKTAYLWQEVFRKESIANIIQHFIRLD  277

Query  120   GKKTDPLTKKTLIFPRYHQLNVVRKLLSHAAQTGVGHKYLIQHSAGSGKSNSITWAAYQL  179
             G     L K+TL+FPRYHQ++VVR+L+ H +  GVG+ YLIQHSAGSGKSNSITWAAYQL
Sbjct  278   GSSKKQLDKRTLFFPRYHQMDVVRRLVDHCSVNGVGQTYLIQHSAGSGKSNSITWAAYQL  337

Query  180   IETYPAKLDLPGVRALDAPLFDSVIVVTDRRLLDKQLRDNIKDFSEVKNIVAPALKSSDL  239
             IETYP   DLPG R+ + PLFDSVIVVTDRRLLDKQLRDNIK+FSEVKNIVAPA+KSS+L
Sbjct  338   IETYPISDDLPGSRGKEVPLFDSVIVVTDRRLLDKQLRDNIKEFSEVKNIVAPAFKSSEL  397

Query  240   KAALENGKKIIITTIQKFPFIIDGIEDLGDKRFAVIIDEAHSGQSGIASDKMNQAMGGDP  299
             K+ALENGKKIIITTIQKFP+I+DGI DL+D+RFAVIIDEAHS+Q G   DK+N+AMG  +
Sbjct  398   KSALENGKKIIITTIQKFPYIVDGIADLSDRRFAVIIDEAHSSQDGHNQDKLNEAMGFVS  457

Query  300   DEDDAQDKILAAMQARKMRGNASYFAFTATPKPITLEKFGEQQSDGRFRPFHLYSMKQAI  359
             +  D  DK L + + RKMR+NASYFAFTATPK  TLEKFG++Q+DG + PFHLYSMKQAI
Sbjct  458   E--DVLDKALQSAKNRKMRSNASYFAFTATPKNTTLEKFGQRQADGTYVPFHLYSMKQAI  515

Query  360   EEGFILDVLANYTTYKGYYEIQKSIEDNPLFDTSKAQKKLRAYVERSQQTINTKAEIMVE  419
             EEGFILDV+ANYTTYK+YYEI+KSI+DNP FD+ KAQK+LRAYVE SQ+TI+TKAEIM+E
Sbjct  516   EEGFILDVIANYTTYKSYYEIEKSIQDNPEFDSKKAQKRLRAYVEASQETIDTKAEIMLE  575

Query  420   NFIDKVVNPKKLRGKGKGMIVTQNIEVAIRYYKAVQAELAKRGNPFKALIAFSGEKEVDG  479
             +FI  VVN KKL+GKGKGM+VTQNIE AIRYY+A+  +L K GNPFK  IAFSG KEVDG
Sbjct  576   HFIKHVVNGKKLKGKGKGMVVTQNIESAIRYYRALTIQLNKMGNPFKVAIAFSGSKEVDG  635

Query  480   VKYTETEMNGVPEDKTRSEFD-----------------KDEFRLLIVANKYLTGFDQPKL  522
             + YTE+++NG PE+ T+  FD                 +D +RLL+VANKYLTGFDQPKL
Sbjct  636   IEYTEADINGFPEGDTKDYFDVNYKRKEPDSPIPKHVDQDAYRLLVVANKYLTGFDQPKL  695

Query  523   CAMYVDKKLQSVLAVQALSRLNRSSPKLGKRTEDLFVLDFFNSIEDIKAAFDPFFTVTTL  582
             CAMYVDKKL SVL VQALSRLNRS+PK GK+TEDLFVLDFFNS++DIK+AFDPF+T TTL
Sbjct  696   CAMYVDKKLASVLCVQALSRLNRSAPKYGKKTEDLFVLDFFNSVDDIKTAFDPFYTSTTL  755

Query  583   SEATDVNVLHELKAALDDVGVYEWSEVEEFCKRFFDGEDSEKLSPLIDVAAERFNTGLEL  642
             SEATDVNVLHELK  +DD GVYEW EVEEF KRFF+G +++ LSP+ID+AA RFN  LEL
Sbjct  756   SEATDVNVLHELKDDMDDTGVYEWFEVEEFNKRFFEGREAQDLSPIIDIAAARFNHELEL  815

Query  643   EDPEKIDFKIKAKQFVKIYGQMAAIMPFEVEAWEKLFWFLKFLVPKLNIKDPNQdalddl  702
             E+  K+DFK+KAKQFVKIYGQ+A+IMP+EV  WEKLFWFLKFL+PKL++ DP+++ALD L
Sbjct  816   ENEFKVDFKVKAKQFVKIYGQIASIMPYEVVQWEKLFWFLKFLIPKLSVEDPDKEALDSL  875

Query  703   lkavdlSSYGLERTKLNQTIGLDTSEAELDPQNPTPRGYREGEVQEDPLEEIIRSFNERW  762
             L +VDLSSYGL+R KLN++I LD SE+ELDPQNP PRG    E + DPL+EII+ FNERW
Sbjct  876   LDSVDLSSYGLQRVKLNHSIELDDSETELDPQNPNPRGAYGPEAEKDPLDEIIKIFNERW  935

Query  763   FQGWSATPEEQRIKFLNIVESVQAHPDFEKKFDENSDPYSRNLAFEKIMKEVMLKRRKEE  822
             FQGWSATPEEQR+KF+NI ES++ HPDFE K+++N+DP +R+LAFEK++KE+ML+RRK+E
Sbjct  936   FQGWSATPEEQRVKFVNIAESIRNHPDFEAKYQNNADPHTRELAFEKMLKEIMLQRRKDE  995

Query  823   LELYKLHNQDEAFRSA  838
             LELYKL  QD AF+++
Sbjct  996   LELYKLFAQDPAFKAS  1011

50) APA32_43180 in NC_017149


> EU272902|14|G13|167832520|ACA01830.1|Vibrio_cholerae_Amazonia_3509|-|13968..17036|-|VPI2_0013c|type 
I restriction enzyme 
HsdR
Length=1022

 Score =  985 bits (3734),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 602/856 (71%), Positives = 727/856 (85%), Gaps = 20/856 (2%)

Query  1     MDMVLFLNGLPIVTLELKNAWTHQTARYHGQKQYRE-RDANQTLLRFGRVLVHMTADTDE  59
             +DMVLF+NG+P++TLELKN+WT Q A YHGQKQYR+ RDANQ LL F+R LVHM+ DTDE
Sbjct  158   IDMVLFINGIPLITLELKNPWTGQNAVYHGQKQYRDDRDANQPLLNFARCLVHMAVDTDE  217

Query  60    VWMATKLAGASTFFLPFNKGHNEgagnppnpngHKTSYLWEEVLQPQSLAGIIQHFVLLE  119
             V M+TKLAG +TFFLPFNKG N G GNP NP+GHKT+YLW+EV++ +S+A IIQHF+ L+
Sbjct  218   VYMTTKLAGKNTFFLPFNKGFNFGKGNPINPHGHKTAYLWQEVFRKESIANIIQHFIRLD  277

Query  120   GKKTDPLTKKTLIFPRYHQLNVVRKLLSHAAQTGVGHKYLIQHSAGSGKSNSITWAAYQL  179
             G     L K+TL+FPRYHQ++VVR+L+ H +  GVG+ YLIQHSAGSGKSNSITWAAYQL
Sbjct  278   GSSKKQLDKRTLFFPRYHQMDVVRRLVDHCSVNGVGQTYLIQHSAGSGKSNSITWAAYQL  337

Query  180   IETYPAKLDLPGVRALDAPLFDSVIVVTDRRLLDKQLRDNIKDFSEVKNIVAPALKSSDL  239
             IETYP   DLPG R+ + PLFDSVIVVTDRRLLDKQLRDNIK+FSEVKNIVAPA+KSS+L
Sbjct  338   IETYPISDDLPGSRGKEVPLFDSVIVVTDRRLLDKQLRDNIKEFSEVKNIVAPAFKSSEL  397

Query  240   KAALENGKKIIITTIQKFPFIIDGIEDLGDKRFAVIIDEAHSGQSGIASDKMNQAMGGDP  299
             K+ALENGKKIIITTIQKFP+I+DGI DL+D+RFAVIIDEAHS+Q G   DK+N+AMG  +
Sbjct  398   KSALENGKKIIITTIQKFPYIVDGIADLSDRRFAVIIDEAHSSQDGHNQDKLNEAMGFVS  457

Query  300   DEDDAQDKILAAMQARKMRGNASYFAFTATPKPITLEKFGEQQSDGRFRPFHLYSMKQAI  359
             +  D  DK L + + RKMR+NASYFAFTATPK  TLEKFG++Q+DG + PFHLYSMKQAI
Sbjct  458   E--DVLDKALQSAKNRKMRSNASYFAFTATPKNTTLEKFGQRQADGTYVPFHLYSMKQAI  515

Query  360   EEGFILDVLANYTTYKGYYEIQKSIEDNPLFDTSKAQKKLRAYVERSQQTINTKAEIMVE  419
             EEGFILDV+ANYTTYK+YYEI+KSI+DNP FD+ KAQK+LRAYVE SQ+TI+TKAEIM+E
Sbjct  516   EEGFILDVIANYTTYKSYYEIEKSIQDNPEFDSKKAQKRLRAYVEASQETIDTKAEIMLE  575

Query  420   NFIDKVVNPKKLRGKGKGMIVTQNIEVAIRYYKAVQAELAKRGNPFKALIAFSGEKEVDG  479
             +FI  VVN KKL+GKGKGM+VTQNIE AIRYY+A+  +L K GNPFK  IAFSG KEVDG
Sbjct  576   HFIKHVVNGKKLKGKGKGMVVTQNIESAIRYYRALTIQLNKMGNPFKVAIAFSGSKEVDG  635

Query  480   VKYTETEMNGVPEDKTRSEFD-----------------KDEFRLLIVANKYLTGFDQPKL  522
             + YTE+++NG PE+ T+  FD                 +D +RLL+VANKYLTGFDQPKL
Sbjct  636   IEYTEADINGFPEGDTKDYFDVNYKRKEPDSPIPKHVDQDAYRLLVVANKYLTGFDQPKL  695

Query  523   CAMYVDKKLQSVLAVQALSRLNRSSPKLGKRTEDLFVLDFFNSIEDIKAAFDPFFTVTTL  582
             CAMYVDKKL SVL VQALSRLNRS+PK GK+TEDLFVLDFFNS++DIK+AFDPF+T TTL
Sbjct  696   CAMYVDKKLASVLCVQALSRLNRSAPKYGKKTEDLFVLDFFNSVDDIKTAFDPFYTSTTL  755

Query  583   SEATDVNVLHELKAALDDVGVYEWSEVEEFCKRFFDGEDSEKLSPLIDVAAERFNTGLEL  642
             SEATDVNVLHELK  +DD GVYEW EVEEF KRFF+G +++ LSP+ID+AA RFN  LEL
Sbjct  756   SEATDVNVLHELKDDMDDTGVYEWFEVEEFNKRFFEGREAQDLSPIIDIAAARFNHELEL  815

Query  643   EDPEKIDFKIKAKQFVKIYGQMAAIMPFEVEAWEKLFWFLKFLVPKLNIKDPNQdalddl  702
             E+  K+DFK+KAKQFVKIYGQ+A+IMP+EV  WEKLFWFLKFL+PKL++ DP+++ALD L
Sbjct  816   ENEFKVDFKVKAKQFVKIYGQIASIMPYEVVQWEKLFWFLKFLIPKLSVEDPDKEALDSL  875

Query  703   lkavdlSSYGLERTKLNQTIGLDTSEAELDPQNPTPRGYREGEVQEDPLEEIIRSFNERW  762
             L +VDLSSYGL+R KLN++I LD SE+ELDPQNP PRG    E + DPL+EII+ FNERW
Sbjct  876   LDSVDLSSYGLQRVKLNHSIELDDSETELDPQNPNPRGAYGPEAEKDPLDEIIKIFNERW  935

Query  763   FQGWSATPEEQRIKFLNIVESVQAHPDFEKKFDENSDPYSRNLAFEKIMKEVMLKRRKEE  822
             FQGWSATPEEQR+KF+NI ES++ HPDFE K+++N+DP +R+LAFEK++KE+ML+RRK+E
Sbjct  936   FQGWSATPEEQRVKFVNIAESIRNHPDFEAKYQNNADPHTRELAFEKMLKEIMLQRRKDE  995

Query  823   LELYKLHNQDEAFRSA  838
             LELYKL  QD AF+++
Sbjct  996   LELYKLFAQDPAFKAS  1011

51) CtCNB1_1528 in NC_013446


> EU272902|14|G13|167832520|ACA01830.1|Vibrio_cholerae_Amazonia_3509|-|13968..17036|-|VPI2_0013c|type 
I restriction enzyme 
HsdR
Length=1022

 Score =  939 bits (3559),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 585/1024 (58%), Positives = 784/1024 (77%), Gaps = 55/1024 (5%)

Query  1     MVSQTNEAALETHIENALA-----------------KDGYCIGNPADFDREFAIDGKLFW  43
             MVS+TNE ALE+ IE++LA                 +D Y IG+P+DFD+++A+D +LFW
Sbjct  4     MVSKTNEQALEAAIEKGLAGICKEELALGEAPLNYNNDLYLIGSPSDFDKQYALDTRLFW  63

Query  44    QFLEATQPKELAKLK--DRPNWQRLLLERLNKKIKKDSVLAVLKKGLDIDDAHFDLLYRL  101
             QFLE TQ+ EL KLK     +WQR +LER+++ I +++VL +LKKGLD+DDA + L+Y  
Sbjct  64    QFLEDTQASELEKLKRTSPHDWQRKILERFDRMIMRHGVLRLLKKGLDVDDAFLSLMYPA  123

Query  102   PYNDLNPEVVANFQANIFSVTRQVHYSESDTFKSVDMVLFVNGLAIATLELKNPWTGQN-  160
             P    +  V  +F AN+FSVTRQV YS+++ +  +DMVLF+NG+++ TLELKNPWTGQN 
Sbjct  124   PLASSSEKVKKDFSANLFSVTRQVCYSNANPLEEIDMVLFINGIPLITLELKNPWTGQNA  183

Query  161   VHNAIKQYRTDRDPREPLFEFGRCLVHFAVDPDEAFMCAQLAGNDSNFLPFNKGFNFGKG  220
             V ++ KQYR DRD+ +PL++F+RCLVH AVD DE +M ++LAG+++ FLPFNKGFNFGKG
Sbjct  184   VYHGQKQYRDDRDANQPLLNFARCLVHMAVDTDEVYMTTKLAGKNTFFLPFNKGFNFGKG  243

Query  221   NPVNPKGHKTAYLWEDILPRRSLTNIIEQFAKFTVEKDKKTGKERKALFFPRYHQLDVVR  280
             NP+NP GHKTAYLW++++ + S++NII++F +  ++   K   ++++LFFPRYHQ+DVVR
Sbjct  244   NPINPHGHKTAYLWQEVFRKESIANIIQHFIR--LDGSSKKQLDKRTLFFPRYHQMDVVR  301

Query  281   GILADAKQNGIGQTYLIQHSAGSGKSNSITWLAYQLVELYDTAGT--------ANVFNSv  332
              ++ +   NG+GQTYLIQHSAGSGKSNSITW AYQL+E Y  ++           +F+SV
Sbjct  302   RLVDHCSVNGVGQTYLIQHSAGSGKSNSITWAAYQLIETYPISDDLPGSRGKEVPLFDSV  361

Query  333   vvvtdrrvldtQLKDNIKLFSETKNIVAHAESAAELKAHLELGKKIIITTVQKFPFIVDG  392
             +VVTDRR+LD QL+DNIK FSE KNIVA A  ++ELK+ LE GKKIIITT+QKFP+IVDG
Sbjct  362   IVVTDRRLLDKQLRDNIKEFSEVKNIVAPAFKSSELKSALENGKKIIITTIQKFPYIVDG  421

Query  393   IDDLTDRNFAVIIDEAHSSQSGSASDKLNMTLGAEDEEVPEDLQDKILAAMKGRKMSQNA  452
             I DL+DR FAVIIDEAHSSQ G   DKLN ++G     V+ED+ DK L + K RKM  NA
Sbjct  422   IADLSDRRFAVIIDEAHSSQDGHNQDKLNEAMGF----VSEDVLDKALQSAKNRKMRSNA  477

Query  453   SYFAFTATPKPATLEKFGRQGPDGKFYPFHLYSMKQAIEEKFILDVLEKYTTYKSYYEVQ  512
             SYFAFTATPK +TLEKFG++ +DG + PFHLYSMKQAIEE FILDV+ +YTTYKSYYE++
Sbjct  478   SYFAFTATPKNTTLEKFGQRQADGTYVPFHLYSMKQAIEEGFILDVIANYTTYKSYYEIE  537

Query  513   KSVEENPLFDTAKAQKKLKAFVEASPRTIEVKAKIMVDHFMSNVWQAKKLKGKAKAMVVT  572
             KS+++NP FD+ KAQK+L+A+VEAS  TI+ KA IM++HF+ +V ++KKLKGK+K+MVVT
Sbjct  538   KSIQDNPEFDSKKAQKRLRAYVEASQETIDTKAEIMLEHFIKHVVNGKKLKGKGKGMVVT  597

Query  573   RNIECAIRYFFAIRTALQEANAPFKALVAFSGEKTVDGIKYTEDGINGITARD-------  625
             +NIE AIRY+ A+   L+    PFK  +AFSG K VDGI YTE +ING+   D       
Sbjct  598   QNIESAIRYYRALTIQLNKMGNPFKVAIAFSGSKEVDGIEYTEADINGFPEGDTKDYFDV  657

Query  626   ----------LPEEFEKDDFKILVVANKYLTGFDEPMLHTMYVDKKLQGVLAVQALSRLN  675
                       +P + ++D +++LVVANKYLTGFD+P L +MYVDKKL +VL VQALSRLN
Sbjct  658   NYKRKEPDSPIPKHVDQDAYRLLVVANKYLTGFDQPKLCAMYVDKKLASVLCVQALSRLN  717

Query  676   RCNWKLGKT--DTFVLDFYNTVDDIKAAFDPFYTATTLSEPTDVNVLHDLKDVLDNFGIY  733
             R   K GK   D FVLDF+N+VDDIK+AFDPFYT+TTLSE+TDVNVLH+LKD +D+ G+Y
Sbjct  718   RSAPKYGKKTEDLFVLDFFNSVDDIKTAFDPFYTSTTLSEATDVNVLHELKDDMDDTGVY  777

Query  734   DWSEVTTFNEKFFASAEAEELHPIIDAVVARF--DADLDDEQRIDFKIKAKQFVKIYAQV  791
             +W EV  FN +FF + EA++L PIID   ARF  + +L++E ++DFK+KAKQFVKIY+Q+
Sbjct  778   EWFEVEEFNKRFFEGREAQDLSPIIDIAAARFNHELELENEFKVDFKVKAKQFVKIYGQI  837

Query  792   AAIIPFNNVNWEMLHWFLKFLIPKLKVKDPDQDKLDELLNSVDLSTYGLERSRLETKISL  851
             A+I+P++ V+WE L WFLKFLIPKL V DPD++ LD LL+SVDLS+YGL+R +L+  I L
Sbjct  838   ASIMPYEVVQWEKLFWFLKFLIPKLSVEDPDKEALDSLLDSVDLSSYGLQRVKLNHSIEL  897

Query  852   DDSETELEPQNPNVRGGHFGDGDKDPLDEIVRAFNERHFAGWEATPEEQRVKFINIAKHV  911
             DDSETEL+PQNPN RG+   +++KDPLDEI++ FNER F GW ATPEEQRVKF+NIA  +
Sbjct  898   DDSETELDPQNPNPRGAYGPEAEKDPLDEIIKIFNERWFQGWSATPEEQRVKFVNIAESI  957

Query  912   MNHADYKAQVEDNPDTQNRQLALERLIQQAISVERRRELDLYKRYASDPDFKRAFDASIF  971
              NH+D+ A+ ++N+D + R+LA+E+++++ +   R+ EL+LYK +A DP FK +   S+ 
Sbjct  958   RNHPDFEAKYQNNADPHTRELAFEKMLKEIMLQRRKDELELYKLFAQDPAFKASWTQSMQ  1017

Query  972   RMLS  975
             RM++
Sbjct  1018  RMVG  1021

52) Oscil6304_1849 in NC_019693


> EU272902|14|G13|167832520|ACA01830.1|Vibrio_cholerae_Amazonia_3509|-|13968..17036|-|VPI2_0013c|type 
I restriction enzyme 
HsdR
Length=1022

 Score =  935 bits (3541),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 582/1023 (57%), Positives = 773/1023 (76%), Gaps = 52/1023 (5%)

Query  1     MVSKTNEKALEDLIENRL---------LNDAG-------YQQGSSKNFDPEFAIDTAKFW  44
             MVSKTNE+ALE  IE+ L         L +A        Y  GS+ +FD ++A+DT  FW
Sbjct  4     MVSKTNEQALEAAIEKGLAGICKEELALGEAPLNYNNDLYLIGSPSDFDKQYALDTRLFW  63

Query  45    QFLETTQPEELKKL--ADRPNWQRMILERIDRQIKKNGIVSVLKKGVAIDDAELTLYYSH  102
             QFLE TQ+ EL KL  +   +WQR ILER+DR I ++G++ +LKKG+ +DDA L+L Y+ 
Sbjct  64    QFLEDTQASELEKLKRTSPHDWQRKILERFDRMIMRHGVLRLLKKGLDVDDAFLSLMYPA  123

Query  103   PYNDLNPEIAANFEQNIFSISRQVHFSATDNAPSIDLVIFLNGLAIATLELKNPWTNQ-T  161
             P    +  +  +F  N+FS++RQV +S ++    ID+V+F+NG+++ TLELKNPWT Q +
Sbjct  124   PLASSSEKVKKDFSANLFSVTRQVCYSNANPLEEIDMVLFINGIPLITLELKNPWTGQNA  183

Query  162   VYHAKKQYCD-RNPKEPLFNFGRCLVHFAADTDEIWMTTKLTGKNTYFLPFNQGNNHGKG  220
             VYH++KQY D R++++PL+NF+RCLVH A DTDE+ MTTKL+GKNT+FLPFN+G N GKG
Sbjct  184   VYHGQKQYRDDRDANQPLLNFARCLVHMAVDTDEVYMTTKLAGKNTFFLPFNKGFNFGKG  243

Query  221   NPTNPNGHKTSYLWEDVLSRTSLAHILEHFVLLEGKPKDPLPDKTLIFPRYHQRDVVNQL  280
             NP NP+GHKT+YLW++V+ + S+A+I++HF+ L+G +K  L  +TL+FPRYHQ DVV +L
Sbjct  244   NPINPHGHKTAYLWQEVFRKESIANIIQHFIRLDGSSKKQLDKRTLFFPRYHQMDVVRRL  303

Query  281   LTDAKTNGPGQTYLIQHSAGSGKSNSITWLAFQLIQLYQTHQS--------EPLFNSVIV  332
             + +   NG GQTYLIQHSAGSGKSNSITW A+QLI+ Y   +          PLF+SVIV
Sbjct  304   VDHCSVNGVGQTYLIQHSAGSGKSNSITWAAYQLIETYPISDDLPGSRGKEVPLFDSVIV  363

Query  333   VTDRRNLDKQLRDNIKDFSQVKNIIAHANRSEDLKNALESGKKIIISTIQKFRFIVDGIE  392
             VTDRR LDKQLRDNIK+FS+VKNI+A A +S +LK+ALE+GKKIII+TIQKF +IVDGI 
Sbjct  364   VTDRRLLDKQLRDNIKEFSEVKNIVAPAFKSSELKSALENGKKIIITTIQKFPYIVDGIA  423

Query  393   GLGDRRFAVIIDEAHssqsgssadsLNTTLNQNEDEAEPEDNQDKILKVMQGRKLSKNAS  452
             +L+DRRFAVIIDEAHSSQ G + D LN ++        +ED  DK L+  + RK+  NAS
Sbjct  424   DLSDRRFAVIIDEAHSSQDGHNQDKLNEAMG-----FVSEDVLDKALQSAKNRKMRSNAS  478

Query  453   YFAFTATPKNTTLEKFGQRQNDGSFTPHHLYSMKQAIEEGFILDVLANYTTYKSYYEIQK  512
             YFAFTATPKNTTLEKFGQRQ DG++ P HLYSMKQAIEEGFILDV+ANYTTYKSYYEI+K
Sbjct  479   YFAFTATPKNTTLEKFGQRQADGTYVPFHLYSMKQAIEEGFILDVIANYTTYKSYYEIEK  538

Query  513   SIEDNPQFDTAQAQKKLKAYVESNPKTIATKAEIMVNHFLEQVVSPKKLKGQAKGMVVTR  572
             SI+DNP+FD+ +AQK+L+AYVE++  TI TKAEIM++HF+ +VV+ KKLKG++KGMVVT+
Sbjct  539   SIQDNPEFDSKKAQKRLRAYVEASQETIDTKAEIMLEHFIKHVVNGKKLKGKGKGMVVTQ  598

Query  573   NIKTAIRYYSEIQKLLKAKNADFRAIVAFSGKKKVDGIEHTEESLNGFPSQKIEEKFQSN  632
             NI +AIRYY  +   L+     F+  +AFSG K VDGIE TE  +NGFP     + F+ N
Sbjct  599   NIESAIRYYRALTIQLNKMGNPFKVAIAFSGSKEVDGIEYTEADINGFPEGDTKDYFDVN  658

Query  633   -----------------DYRLLVVANKYLTGFDEPLLHTMYVDKKLQGVLAVQALSRLNR  675
                               YRLLVVANKYLTGFD+P L +MYVDKKL +VL VQALSRLNR
Sbjct  659   YKRKEPDSPIPKHVDQDAYRLLVVANKYLTGFDQPKLCAMYVDKKLASVLCVQALSRLNR  718

Query  676   CNNKLGK--NDTFILDFANSPSDIKAAFDPFYTATELSEATDVNVLHDLKESLDGLGVYE  733
                K GK  +D F+LDF NS  DIK+AFDPFYT+T LSEATDVNVLH+LK+ +D+ GVYE
Sbjct  719   SAPKYGKKTEDLFVLDFFNSVDDIKTAFDPFYTSTTLSEATDVNVLHELKDDMDDTGVYE  778

Query  734   IHEINEFNQLFFDGVEADQLSPIIDTAAERFNQELELSEEDKIDFKIKAKQFVKVYAQLA  793
               E++EFN+ FF+G EA++LSPIID AA RFN+ELEL +E K+DFK+KAKQFVK+Y+Q+A
Sbjct  779   WFEVEEFNKRFFEGREAQDLSPIIDIAAARFNHELELENEFKVDFKVKAKQFVKIYGQIA  838

Query  794   CLIPFHNLAWEKLHWFLKFLIPKLIVKNPQQEQLDELLNSVDLSTYGIERVTLNAAIALE  853
              ++P++ + WEKL WFLKFLIPKL V +P++E LD LL+SVDLS+YG++RV LN +I L+
Sbjct  839   SIMPYEVVQWEKLFWFLKFLIPKLSVEDPDKEALDSLLDSVDLSSYGLQRVKLNHSIELD  898

Query  854   ESSSEIKPQNPNPRGYHEAEKEYDPLDEIIALFNQTHFAQWDATPEEQKIKLINLARNVA  913
             +S +E+ PQNPNPRG   +E E DPLDEII +FN+  F  W ATPEEQ++K++N+A ++ 
Sbjct  899   DSETELDPQNPNPRGAYGPEAEKDPLDEIIKIFNERWFQGWSATPEEQRVKFVNIAESIR  958

Query  914   QNTDYQTQVVNNPDPQNSRMAIGKLIKQAVNHERRKELTLYKNYSQDPDFERALENSIIR  973
             ++ D++++  NN+DP+   +A+ K++K+ + + R+ EL LYK ++QDP F  +  +S+ R
Sbjct  959   NHPDFEAKYQNNADPHTRELAFEKMLKEIMLQRRKDELELYKLFAQDPAFKASWTQSMQR  1018

Query  974   ILE  976
             ++ 
Sbjct  1019  MVG  1021

53) WQG_21420 in NC_020515


> EU272902|14|G13|167832520|ACA01830.1|Vibrio_cholerae_Amazonia_3509|-|13968..17036|-|VPI2_0013c|type 
I restriction enzyme 
HsdR
Length=1022

 Score =  922 bits (3493),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 558/989 (57%), Positives = 754/989 (77%), Gaps = 38/989 (3%)

Query  22    FIQASPSGFNARFALDEANFWAFLSESQADKLADFKRLNPNDWQAKILARLDNVWKREGI  81
             ++ +SPS+F+ ++ALD   FW FL ++QA  L  +KR +P+DWQ KIL R+D +  R+G+
Sbjct  43    YLIGSPSDFDKQYALDTRLFWQFLEDTQASELEKLKRTSPHDWQRKILERFDRMIMRHGV  102

Query  82    LHLFKKGLDVDNVHLDLFFVPPLANSPQRVAELFVQNRFSVMRQVPYSAQSS-ETVDMAV  140
             L+L+KKGLDVD+  L L + +PLA+S+++V   F  N FSV RQV YS  ++ E +DM +
Sbjct  103   LRLLKKGLDVDDAFLSLMYPAPLASSSEKVKKDFSANLFSVTRQVCYSNANPLEEIDMVL  162

Query  141   FINGLPFATMELKNEWTGQST-YHAKQQYRH-RDNTQALFQPARTLVHFAIDSQEAYMTT  198
             FING+P+ T+ELKN WTGQ++ YH+++QYR+ RD  Q+L++ AR LVH A+D++E YMTT
Sbjct  163   FINGIPLITLELKNPWTGQNAVYHGQKQYRDDRDANQPLLNFARCLVHMAVDTDEVYMTT  222

Query  199   KICGNNTFFLPFNQgnhhgkgnppnpngFNTAYLWQEVFQKQSIAGIILHFARLEFDDER  258
             K+ G+NTFFLPFN+G + GKGNP NP+G +TAYLWQEVF+K+SIA II HF RL  D+  
Sbjct  223   KLAGKNTFFLPFNKGFNFGKGNPINPHGHKTAYLWQEVFRKESIANIIQHFIRL--DGSS  280

Query  259   KKDLSKATLYFPRYHQLDVVRKLVADVAQNGVGKRYLIQHSAGSGKSNSITWLAFHLIEI  318
             KK+L K TL+FPRYHQ+DVVR+LV + + NGVG+ YLIQHSAGSGKSNSITW A++LIE 
Sbjct  281   KKQLDKRTLFFPRYHQMDVVRRLVDHCSVNGVGQTYLIQHSAGSGKSNSITWAAYQLIET  340

Query  319   Y--------GKAREKPIFDSVIVVTDRKVLDKQISDNIRAFSSVKNIIAHADRATDLKNA  370
             Y        ++++E P+FDSVIVVTDR++LDKQ+ DNI+ FS VKNI+A A ++++LK+A
Sbjct  341   YPISDDLPGSRGKEVPLFDSVIVVTDRRLLDKQLRDNIKEFSEVKNIVAPAFKSSELKSA  400

Query  371   MENGKRIIITTIQKFPFIVDGIADMADKKFAVIIDEAHSSQSGTAHDNMNRAMGAVEESD  430
             +ENGK+IIITTIQKFP+IVDGIAD++D++FAVIIDEAHSSQ G  +D++N AMG V E D
Sbjct  401   LENGKKIIITTIQKFPYIVDGIADLSDRRFAVIIDEAHSSQDGHNQDKLNEAMGFVSE-D  459

Query  431   AQDLILSAMQARKMRHNASYFAFTATPKNSTLEKFGEKQTACNADGKPIFKPFHLYSMKQ  490
               D  L + + RKMR NASYFAFTATPKN+TLEKFG++Q+         + PFHLYSMKQ
Sbjct  460   VLDKALQSAKNRKMRSNASYFAFTATPKNTTLEKFGQRQAD------GTYVPFHLYSMKQ  513

Query  491   AIEEGFILDVLKNYTTYQSYYEVQKAVEDNPEFDVKKAQQRLKAFVERTPESIAVKADIM  550
             AIEEGFILDV+ NYTTY+SYYE++K+++DNPEFD KKAQ+RL+A+VE + E+I  KA+IM
Sbjct  514   AIEEGFILDVIANYTTYKSYYEIEKSIQDNPEFDSKKAQKRLRAYVEASQETIDTKAEIM  573

Query  551   LSHFLDRVVKTKRLKGKAKAMVITQNIETAIRYYLAICQWLDEKGNPFKAVVAFSGEKNV  610
             L HF+ +VV+ K+LKGK+K+MV+TQNIE+AIRYY A+   L+  GNPFK  +AFSG K+V
Sbjct  574   LEHFIKHVVNGKKLKGKGKGMVVTQNIESAIRYYRALTIQLNKMGNPFKVAIAFSGSKEV  633

Query  611   DGVVYTESQLNGFDENKTKAMFDT-----------------DDYRILVVANKYLTGFDQP  653
             DG+ YTE+++NGF E  TK  FD                  D YR+LVVANKYLTGFDQP
Sbjct  634   DGIEYTEADINGFPEGDTKDYFDVNYKRKEPDSPIPKHVDQDAYRLLVVANKYLTGFDQP  693

Query  654   KLCAMYVDKPLAGVLCVQALSRLNRSSPKYGKSADDLFILDFFNKTEDIQAAFEPFYTET  713
             KLCAMYVDK LA+VLCVQALSRLNRS+PKYGK ++DLF+LDFFN  +DI++AF+PFYT T
Sbjct  694   KLCAMYVDKKLASVLCVQALSRLNRSAPKYGKKTEDLFVLDFFNSVDDIKTAFDPFYTST  753

Query  714   ELEGETDINILYDLQNELDEAGIYELDEVSRFVERLFAGADMAELQTLNQVCANRFNHGL  773
              L   TD+N+L +L++++D++G+YE  EV  F  R+F G +  +L  + ++ A RFNH L
Sbjct  754   TLSEATDVNVLHELKDDMDDTGVYEWFEVEEFNKRFFEGREAQDLSPIIDIAAARFNHEL  813

Query  774   GWEREQKVDFKIKAKQFVKVYNQMASIIAFENREWEKRYWFLKLLIPKLNVADDEK-VID  832
               E E KVDFK+KAKQFVK+Y Q+ASI+++E  +WEK +WFLK+LIPKL+V D +K  +D
Sbjct  814   ELENEFKVDFKVKAKQFVKIYGQIASIMPYEVVQWEKLFWFLKFLIPKLSVEDPDKEALD  873

Query  833   DLLEKVNLSSYALAISEKEHAITLSDETGTFTPSNSTVHGIHEDDEERDELDNIIKTFNE  892
              LL+ V+LSSY+L     +H+I L D    + P N+  +G    + E+D LD+IIK FNE
Sbjct  874   SLLDSVDLSSYGLQRVKLNHSIELDDSETELDPQNPNPRGAYGPEAEKDPLDEIIKIFNE  933

Query  893   RWFDGWGDTPEERRIRFVAVVEKIQQHKDFESKYLAIQDPALRQVIFSDIVKEVMRNRRE  952
             RWF+GW+ TPEE+R++FV + E I++H DFE+KY    DP  R++ F  ++KE+M +RR 
Sbjct  934   RWFQGWSATPEEQRVKFVNIAESIRNHPDFEAKYQNNADPHTRELAFEKMLKEIMLQRRK  993

Query  953   QEMEIYRQFMRDDSFQKSLIADLQRAVNI  981
             +E+E+Y+ F +D +F+ S    +QR V +
Sbjct  994   DELELYKLFAQDPAFKASWTQSMQRMVGM  1022

54) BVU_3410 in NC_009614


> EU272902|14|G13|167832520|ACA01830.1|Vibrio_cholerae_Amazonia_3509|-|13968..17036|-|VPI2_0013c|type 
I restriction enzyme 
HsdR
Length=1022

 Score =  794 bits (3006),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 506/1038 (49%), Positives = 752/1038 (73%), Gaps = 47/1038 (4%)

Query  5     AKSNEQAFEWLIEQALVGNTKEERKHNKEIADFDTQNPGNEKFYWGRPDDLKKELAIDTV  64
             +K+NEQA+E  IE++L G  KEE        +++     N+ +  G P D+ K+ A+DT 
Sbjct  6     SKTNEQALEAAIEKGLAGICKEELALGEAPLNYN-----NDLYLIGSPSDFDKQYALDTR  60

Query  65    RLWSFLNATQS---EKLKEYKGKDLETALPKQIAKIISTKGILEILRKGIDLDNLEGIKL  121
              +W FL+ TQ+   EKLK     D +  +  ++ ++I   G+L +L+KG+D+D+   + L
Sbjct  61    LFWQFLEDTQASELEKLKRTSPHDWQRKILERFDRMIMRHGVLRLLKKGLDVDD-AFLSL  119

Query  122   FYPKPSEADSEESKRLYAQNQFCVTRQQTFSSSNKGLEIDMVISVNGLPLFTMELKNPWT  181
              YP P  + SE  K+ ++ N F VTRQ  +S++N   EIDMV+ +NG+PL+T+ELKNPWT
Sbjct  120   MYPAPLASSSEKVKKDFSANLFSVTRQVCYSNANPLEEIDMVLFINGIPLITLELKNPWT  179

Query  182   GQTARYNGIKQYKEERNPKEPLLNYGRCLAHFTMDKDEVYFTTRLNEGKTFFMPFNQGLP  241
             GQ A Y+G KQY+++R++++PLLN++RCL H ++D DEVY TT+L   +TFF+PFN+G+ 
Sbjct  180   GQNAVYHGQKQYRDDRDANQPLLNFARCLVHMAVDTDEVYMTTKLAGKNTFFLPFNKGF-  238

Query  242   NGLGAGNPVNENGYKTSYMWERILTKDTLSDIIMNYALFDYGEAKTRKKVPHILRNAKKL  301
               +G GNP+N +G KT+Y+W+ ++ K+++++II ++  +D   + ++K++     + + L
Sbjct  239   -NFGKGNPINPHGHKTAYLWQEVFRKESIANIIQHFIRLD---GSSKKQL-----DKRTL  289

Query  302   IFPRFHQLDVVDKLIADVQENGVGKRYLIEHSAGSGKSNSLTWLAFKLIKSCASSENAVR  361
             +FPR+HQ+DVV +L+ +   NGVG+ YLI+HSAGSGKSNS+TW A++LI + + S++   
Sbjct  290   FFPRYHQMDVVRRLVDHCSVNGVGQTYLIQHSAGSGKSNSITWAAYQLIETYPISDDLPG  349

Query  362   SRGLGQQLFNTVIVVTDRRILDKQITDNIKAFGQSEKTIAHADSSNELKTAIEGGKRIVI  421
             SRG    LF++VIVVTDRR+LDKQ+ DNIK F++  + +A A  S+ELK+A+E GK+I+I
Sbjct  350   SRGKEVPLFDSVIVVTDRRLLDKQLRDNIKEFSEVKNIVAPAFKSSELKSALENGKKIII  409

Query  422   TTIQKFPFICGTIADVSDHNFAIIIDEAHSSQSGIAADKMNASVQRDSDQEGSDTDELIA  481
             TTIQKFP+I + IAD+SD+ FA+IIDEAHSSQ G   DK+N ++       G  +++++ 
Sbjct  410   TTIQKFPYIVDGIADLSDRRFAVIIDEAHSSQDGHNQDKLNEAM-------GFVSEDVLD  462

Query  482   KLI---RDRKMSSNCSYFAFTATPKRETLERFGWQDEEGVFHPFHLYSMKQAIEEGFILD  538
             K +   ++RKM SN SYFAFTATPK  TLE+FG ++ +G + PFHLYSMKQAIEEGFILD
Sbjct  463   KALQSAKNRKMRSNASYFAFTATPKNTTLEKFGQRQADGTYVPFHLYSMKQAIEEGFILD  522

Query  539   VLVNYTTYKSYYELIKSIEENPQYDEKKAQKLLRRTVERHPDTIAVKADTMLQHFDSKVF  598
             V+ NYTTYKSYYE+ KSI++NP++D KKAQK LR  VE   +TI  KA+ ML+HF   V 
Sbjct  523   VIANYTTYKSYYEIEKSIQDNPEFDSKKAQKRLRAYVEASQETIDTKAEIMLEHFIKHVV  582

Query  599   RQRKLKGKAKAMVVTKDIECAIHYYKALTDlvvklklpykvlIAFSGEKEMNGVTYTEAG  658
               +KLKGK+K+MVVT++IE AI+YY+ALT  + K+  P+KV IAFSG KE++G+ YTEA+
Sbjct  583   NGKKLKGKGKGMVVTQNIESAIRYYRALTIQLNKMGNPFKVAIAFSGSKEVDGIEYTEAD  642

Query  659   LNGFAETETAEKFDA-----------------DENRILVVANKYLTGFDQPKLCAMYIDK  701
             +NGF+E +T + FD                  D  R+LVVANKYLTGFDQPKLCAMY+DK
Sbjct  643   INGFPEGDTKDYFDVNYKRKEPDSPIPKHVDQDAYRLLVVANKYLTGFDQPKLCAMYVDK  702

Query  702   PLAGVLAVQSLSRLNRAAPDLSKRSEDLFILDFYNKKDDMEESFNPFYTSTTLSEPTDVN  761
              LA+VL VQ+LSRLNR+AP  +K++EDLF+LDF+N  DD+  +F+PFYTSTTLSE+TDVN
Sbjct  703   KLASVLCVQALSRLNRSAPKYGKKTEDLFVLDFFNSVDDIKTAFDPFYTSTTLSEATDVN  762

Query  762   ILHELRSTLLSIGVFDEEDINQFMEIYMSGAEPDKWVPITDAAAHRFNHEIEFDENGKAD  821
             +LHEL+  +   GV++  ++++F   +  G E++   PI D AA RFNHE+E++++ K D
Sbjct  763   VLHELKDDMDDTGVYEWFEVEEFNKRFFEGREAQDLSPIIDIAAARFNHELELENEFKVD  822

Query  822   FKIKCKQFVKVYSRVAAIMDYEVLNWEKMFWFLRFLIPNLHVDVPGRddlkdlldsvdlN  881
             FK+K KQFVK+Y+++A+IM YEV++WEK+FWFL+FLIP+L V+ P+++ L  LLDSVDL+
Sbjct  823   FKVKAKQFVKIYGQIASIMPYEVVQWEKLFWFLKFLIPKLSVEDPDKEALDSLLDSVDLS  882

Query  882   TYGLRRTGLNEKIELDSSETVLDPTKAAMAGAGTSDDAKEELDVILQEFNDKWFKGWDTT  941
             +YGL+R  LN+ IELD SET LDP ++   GA  ++  K+ LD I++ FN++WF+GW +T
Sbjct  883   SYGLQRVKLNHSIELDDSETELDPQNPNPRGAYGPEAEKDPLDEIIKIFNERWFQGWSAT  942

Query  942   PEEQKVKLTAIVNAIKQDNDYLSLIVGNPDKQAAEEALDKIIDRIVRRQRQKDMSLYKEY  1001
             PEEQ+VK+  I ++I+++ D+ +    N+D ++ E A++K++  I+ ++R+ ++ LYK +
Sbjct  943   PEEQRVKFVNIAESIRNHPDFEAKYQNNADPHTRELAFEKMLKEIMLQRRKDELELYKLF  1002

Query  1002  MNE-DFKINFRSLVTRMI  1018
              ++  FK +    + RM+
Sbjct  1003  AQDPAFKASWTQSMQRMV  1020

55) Bacsa_0517 in NC_015164


> EU272902|14|G13|167832520|ACA01830.1|Vibrio_cholerae_Amazonia_3509|-|13968..17036|-|VPI2_0013c|type 
I restriction enzyme 
HsdR
Length=1022

 Score =  778 bits (2946),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 504/1018 (50%), Positives = 732/1018 (72%), Gaps = 40/1018 (3%)

Query  1     MNKTNEQAFEALIEKALVGTTLEERQQTGVNDIDAQSPDLDKYYWGLLKDMSDKKYAFDM  60
             ++KTNEQA+EA IEK+L G     +++ ++ +   +  + D Y  G   D  DK+YA+D 
Sbjct  5     VSKTNEQALEAAIEKGLAGIC---KEELALGEAPLNYNN-DLYLIGSPSDF-DKQYALDT  59

Query  61    RRLWSFLRTTQQNIIDEYKGKNIEN---ELPKQLSKAIDTFGIIEVLRKGVDIDNIHVTM  117
             R +W FL  TQ + ++  K  + ++    +  ++ + I   G++ +L+KG+D+D+  +++
Sbjct  60    RLFWQFLEDTQASELEKLKRTSPHDWQRKILERFDRMIMRHGVLRLLKKGLDVDDAFLSL  119

Query  118   FYPKPSPADSQLSKEKYIQNQFSVTRQQTFSVSNPGLEIDMVLYVNGLPLFTFEFKNPWT  177
              YP P ++ S+  K  +  N FSVTRQ  +S +NP  EIDMVL++NG+PL+T+E+KNPWT
Sbjct  120   MYPAPLASSSEKVKKDFSANLFSVTRQVCYSNANPLEEIDMVLFINGIPLITLELKNPWT  179

Query  178   HQTAKYDGQKQYREERNPKETLLKFGRCLAHFTMDKNEVYFTTKLNSGKTFFMPFNQGLP  237
              Q A Y+GQKQYR++R++++ LL+F+RCL H ++D +EVY TTKL + +TFF+PFN+G+ 
Sbjct  180   GQNAVYHGQKQYRDDRDANQPLLNFARCLVHMAVDTDEVYMTTKLAGKNTFFLPFNKGFN  239

Query  238   NGQGAGNPVNPNGGYKTAYMWEKVLQKDIVADIIMNYVLFDYGEAKTQKKVPHIMSNAKK  297
              G+G  NP+NP+G  KTAY+W+ V++K+ +A+II +++ +D G +K Q        + + 
Sbjct  240   FGKG--NPINPHG-HKTAYLWQEVFRKESIANIIQHFIRLD-GSSKKQ-------LDKRT  288

Query  298   LIFPRFHQLDVVSKLIVDVAKFGVGKTYLIEHSAGSGKSNSITWLAYKLIDVCPVTMDAV  357
             L+FPR+HQ+DVV +L+ + +  GVG+TYLI+HSAGSGKSNSITW AY+LI+  P++ D  
Sbjct  289   LFFPRYHQMDVVRRLVDHCSVNGVGQTYLIQHSAGSGKSNSITWAAYQLIETYPISDDLP  348

Query  358   RAKTLDSRLYDSVIVVTDRRLLDKQITDNIKAFGKSEKIVAHADTSKDLKKAIEDGKRII  417
              ++  +  L+DSVIVVTDRRLLDKQ+ DNIK F+   +IVA A  S +LK A+E+GK+II
Sbjct  349   GSRGKEVPLFDSVIVVTDRRLLDKQLRDNIKEFSEVKNIVAPAFKSSELKSALENGKKII  408

Query  418   VTTIQKFPYICDSISDVSEHNFAIIIDEAHSSQSGIAADSVNKTIQKDMDCEGADTDELL  477
             +TTIQKFPYI D+I+D+S++ FA+IIDEAHSSQ G   D +N ++       G  ++++L
Sbjct  409   ITTIQKFPYIVDGIADLSDRRFAVIIDEAHSSQDGHNQDKLNEAM-------GFVSEDVL  461

Query  478   EKLM---KDRKMSTNCSYFAFTATPKKETLERFGSEDKDGKFHPFHLYSMKQAIEEGFIL  534
             +K +   K+RKM +N SYFAFTATPK+ TLE+FG  + DG + PFHLYSMKQAIEEGFIL
Sbjct  462   DKALQSAKNRKMRSNASYFAFTATPKNTTLEKFGQRQADGTYVPFHLYSMKQAIEEGFIL  521

Query  535   DVLSNYTTYKSYYELTKSIEDNPEYNNEKAQKLLRRAVEREPRTIEAKAEIMLTHFDAKI  594
             DV++NYTTYKSYYE+ KSI+DNPE+++ KAQK LR  VE    TI++KAEIML HF   +
Sbjct  522   DVIANYTTYKSYYEIEKSIQDNPEFDSKKAQKRLRAYVEASQETIDTKAEIMLEHFIKHV  581

Query  595   FRNHKLKGKAKALVVTKDIECAILYYKALQKLVEARKLPYKILIAFSGEKQIIDKSIGYD  654
                 KLKGK+K++VVT++IE AI YY+AL   ++    P+K+ IAFSG K++   +I Y 
Sbjct  582   VNGKKLKGKGKGMVVTQNIESAIRYYRALTIQLNKMGNPFKVAIAFSGSKEV--DGIEYT  639

Query  655   TPIYNTNNIQAAEPYGDYYVTRRYTEAEMNGFPDTQTAEKFESDDYRILVVANKYLTGFD  714
              +  + N +  ++   DY+    Y   E    PD+  +   + D YR+LVVANKYLTGFD
Sbjct  640   EA--DINGFPEGDT-KDYFDVN-YKRKE----PDSPIPKHVDQDAYRLLVVANKYLTGFD  691

Query  715   QPKLCAMYIDKPLDGVLAVQALSRLNRAAPDLGKLSEDLFILDFYNKIEDIKEAFDPFYT  774
             QPKLCAMY+DK L +VL VQALSRLNR+AP  GK +EDLF+LDF+N ++DIK AFDPFYT
Sbjct  692   QPKLCAMYVDKKLASVLCVQALSRLNRSAPKYGKKTEDLFVLDFFNSVDDIKTAFDPFYT  751

Query  775   ATTLSEATNVNVLHELKATLLGMCVFNMDEVNEFIDLYIRGEEADKWAPIIDVAAQRFNS  834
             +TTLSEAT+VNVLHELK  + +  V++  EV+EF   ++ G EA+  +PIID+AA RFN 
Sbjct  752   STTLSEATDVNVLHELKDDMDDTGVYEWFEVEEFNKRFFEGREAQDLSPIIDIAAARFNH  811

Query  835   EIEWAENGKADFKMKCKQFVKVYSKAAAIMSYEVKDWEKLFWFLRFLIPELYIEPNGGND  894
             E+E  ++ K DFK+K KQFVK+Y++ A+IM+YEV +WEKLFWFL+FLIP L +E  + + 
Sbjct  812   ELELENEFKVDFKVKAKQFVKIYGQIASIMPYEVVQWEKLFWFLKFLIPKLSVEDPDKEA  871

Query  895   IKDLLDYVDLNTYGLRRTVLNETIKLDAGETVIDPNKPIMVNAGGEDDEPKDPLDIILKD  954
             +  LLD VDL++YGL+R  LN++I LD +ET +DP++P    A G + E KDPLD I+K 
Sbjct  872   LDSLLDSVDLSSYGLQRVKLNHSIELDDSETELDPQNPNPRGAYGPEAE-KDPLDEIIKI  930

Query  955   FNERWFKGWDATPDDQKAKLISITKAVTEDEDYQTLVVGNPDKQAVDEAMATIIDRII  1012
             FNERWF+GW ATP++Q+ K+++I+ ++ ++ D+++    N+D ++ + A   ++  I+
Sbjct  931   FNERWFQGWSATPEEQRVKFVNIAESIRNHPDFEAKYQNNADPHTRELAFEKMLKEIM  988

56) LLO_2867 in NC_013861


> EU272902|14|G13|167832520|ACA01830.1|Vibrio_cholerae_Amazonia_3509|-|13968..17036|-|VPI2_0013c|type 
I restriction enzyme 
HsdR
Length=1022

 Score =  630 bits (2380),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 412/988 (42%), Positives = 657/988 (67%), Gaps = 63/988 (6%)

Query  25    YKAGNPQDYERSHAIDLKKLSDFLQATQPEIAEGLNLSVDSPKRTTFLHRLQGEIAKHGI  84
             Y  G+P D+++  A+D + + +FL+ TQ+   E L+ +     +  +L+R++  I +HG+
Sbjct  43    YLIGSPSDFDKQYALDTRLFWQFLEDTQASELEKLKRTSPHDWQRKILERFDRMIMRHGV  102

Query  85    INILRKGIKHGPDTITLFYGSP-TENNTKAKAMFEQNLFSVTRQLRYSSNETQLALDMAI  143
             + +L+KG+  +   ++L Y +P + ++ K K  F  NLFSVTRQ+ YS+ +    +DM +
Sbjct  103   LRLLKKGLDVDDAFLSLMYPAPLASSSEKVKKDFSANLFSVTRQVCYSNANPLEEIDMVL  162

Query  144   FINGLPIVTFELKNKLTKQ-TVEDAVQQYKNDRDPKELLFQFGRCLVHFAVDDHEVRMCT  202
             FING+P++T+ELKN  T Q +V ++ +QY++DRD+++ L++F+RCLVH AVD +EV M T
Sbjct  163   FINGIPLITLELKNPWTGQNAVYHGQKQYRDDRDANQPLLNFARCLVHMAVDTDEVYMTT  222

Query  203   HLKGKSSWFLPFNKGFKDGAGNPPNPEGLATDYLWKEILTPDRLTDIIENYAQIIeekde  262
              L GK++ FLPFNKGF+ G GNP NP+G  T YLW+E++  + +++II+++ ++  +   
Sbjct  223   KLAGKNTFFLPFNKGFNFGKGNPINPHGHKTAYLWQEVFRKESIANIIQHFIRL--DGSS  280

Query  263   ktgkkkfkQIFPRYHQLTVVRKLLESVQIHGAGKRYLIQHSAGSGKSNSIAWLAHQLV--  320
             K    K   +FPRYHQ+ VVR+L++   ++G G+ YLIQHSAGSGKSNSI+W A QL+  
Sbjct  281   KKQLDKRTLFFPRYHQMDVVRRLVDHCSVNGVGQTYLIQHSAGSGKSNSITWAAYQLIET  340

Query  321   --------GLEQNKQAVFDSILVVTDRRILDKQIRDSIKSFAQVSSIVGHAERSGDLRRF  372
                     G   +  ++FDS++VVTDRR+LDKQ+RD+IK F++V +IV+ A +S++L+  
Sbjct  341   YPISDDLPGSRGKEVPLFDSVIVVTDRRLLDKQLRDNIKEFSEVKNIVAPAFKSSELKSA  400

Query  373   ITEGKKIIITTVQKFPFILSEIGNEHRQNKFAIIIDEAHSSQSGKTASKMNMALSENVSE  432
             + +GKKIIITT+QKFP+I+  I+ +  + +FA+IIDEAHSSQ G    K+N A++     
Sbjct  401   LENGKKIIITTIQKFPYIVDGIA-DLSDRRFAVIIDEAHSSQDGHNQDKLNEAMG-----  454

Query  433   SDEDSTEDKINELMESRKMLTNASYFAFTATPKNKTLEIFGEPEPQPDGRIKHHPFHSYT  492
                +   DK  +   +RKM +NASYFAFTATPKN TLE FG+ +++        PFH Y+
Sbjct  455   FVSEDVLDKALQSAKNRKMRSNASYFAFTATPKNTTLEKFGQRQADG----TYVPFHLYS  510

Query  493   MKQAIQEGFILDVLKNYTPVASFYRLTKAVEGDPLFDTKKAQKKLRKYVESNTHAIREKA  552
             MKQAI+EGFILDV+ NYT   S+Y + K+++++P FD+KKAQK+LR YVE++ ++I  KA
Sbjct  511   MKQAIEEGFILDVIANYTTYKSYYEIEKSIQDNPEFDSKKAQKRLRAYVEASQETIDTKA  570

Query  553   EIMIDHFHTHIMGQRKIGGSARAMIVTSGISRAIEYFHAVNDYLKERNLPYKSIVAFSGE  612
             EIM++HF  H++  +K+ G +++M+VT  I  AI Y++A+   L+    P+K  +AFSG 
Sbjct  571   EIMLEHFIKHVVNGKKLKGKGKGMVVTQNIESAIRYYRALTIQLNKMGNPFKVAIAFSGS  630

Query  613   HEYGGQKVTEASLNGF-----------------PSNLIGEKIAEDPYRLLVVADKFLTGY  655
              E +G   TEA +NGF                 P + I   + +D+YRLLVVA+K+LTG+
Sbjct  631   KEVDGIEYTEADINGFPEGDTKDYFDVNYKRKEPDSPIPKHVDQDAYRLLVVANKYLTGF  690

Query  656   DEPLMHTMYVDKPLSGIKAVQTLSRLNRAHPKKY-----DTFVLDFYNDVDTIEKSFSDY  710
             D+P + +MYVDK L+++  VQ+LSRLNR+ P KY     D FVLDF+N VD I  +F  +
Sbjct  691   DQPKLCAMYVDKKLASVLCVQALSRLNRSAP-KYGKKTEDLFVLDFFNSVDDIKTAFDPF  749

Query  711   YRTTILSEETDPNKLHDLQSDLDGYQVYSAEQIHQLAERYLNGADREKLDPILDNCVAVY  770
             Y +T LSE TD N LH+L+ D+D+  VY   +++++  R+++G + + L PI+D   A +
Sbjct  750   YTSTTLSEATDVNVLHELKDDMDDTGVYEWFEVEEFNKRFFEGREAQDLSPIIDIAAARF  809

Query  771   NNELDEDGQ--VDFKGKAKAFIRTYGFLSSILPYNYAEWEKLSIFLNFLVPKLPTPKEED  828
             N+EL+ + +  VDFK KAK F++ YG ++SI+PY+  +WEKL  FL+FL+PKL+    + 
Sbjct  810   NHELELENEFKVDFKVKAKQFVKIYGQIASIMPYEVVQWEKLFWFLKFLIPKLSVEDPDK  869

Query  829   HSI-GILETIDMDSYRAE-VQASINIRLADEDAELDA-VPTSAGGRKAEPEMDQLSNIIR  885
             +++ ++L+++D+ SY  + V+ + +I L D ++ELD+  P + G+  +E+E D L +II+
Sbjct  870   EALDSLLDSVDLSSYGLQRVKLNHSIELDDSETELDPQNPNPRGAYGPEAEKDPLDEIIK  929

Query  886   VFND-LFGNIEWK---DGDKIRQI-ITEEIPGKVASDSAYQNAMKNSDRHNARIEHDRAL  940
             +FN+  F    W    + ++++ + I+E I      ++ YQN   N+D H   +  ++ L
Sbjct  930   IFNERWFQG--WSATPEEQRVKFVNIAESIRNHPDFEAKYQN---NADPHTRELAFEKML  984

Query  941   ARVMVELIADHTELYKQFSDNPSFK-KW  967
               +M++   D+ ELYK F+++P+FK  W
Sbjct  985   KEIMLQRRKDELELYKLFAQDPAFKASW  1012

57) GM18_2921 in NC_014973


> EU272902|14|G13|167832520|ACA01830.1|Vibrio_cholerae_Amazonia_3509|-|13968..17036|-|VPI2_0013c|type 
I restriction enzyme 
HsdR
Length=1022

 Score =  626 bits (2366),  Expect = 2e-180, Method: Compositional matrix adjust.
 Identities = 424/1017 (42%), Positives = 663/1017 (66%), Gaps = 68/1017 (6%)

Query  5     DTSEKGLESIIVASLV--------EEAGYVQGDPQDYDREHAVDLAKLLQFLAATQPDTY  56
              + EKGL +I    L         ++  Y+ G P D+D++ A+D   + QFL  TQ+   
Sbjct  15    AAIEKGLAGICKEELALGEAPLNYNNDLYLIGSPSDFDKQYALDTRLFWQFLEDTQASEL  74

Query  57    EALGIDDEGPKRTQFLHRLQGEIARRGVVDVLRGGIKHGPAHVDLFYGTP-TPGNVKAAE  115
             E L        + ++L+R++  I R+GV+ +L+ G+  + A + L Y +P ++++ K   
Sbjct  75    EKLKRTSPHDWQRKILERFDRMIMRHGVLRLLKKGLDVDDAFLSLMYPAPLASSSEKVKK  134

Query  116   RFAANIFSVTRQLRYSRVDPALSLDMAVFINGLPIATFELKNKLTKQ-TVLDAVQQYQRD  174
              F+AN+FSVTRQ+ YS  +P   +DM +FING+P+ T+ELKN  T Q +V ++ +QY+ D
Sbjct  135   DFSANLFSVTRQVCYSNANPLEEIDMVLFINGIPLITLELKNPWTGQNAVYHGQKQYRDD  194

Query  175   RDPKELLFQFGRCVVHFAVDDHEVRFCTHLKGKGSWFLPFDKGYNDGAGNPPNPHGLATD  234
             RD+++ L++F+RC+VH AVD +EV   T L GK + FLPF+KG+N G GNP NPHG  T 
Sbjct  195   RDANQPLLNFARCLVHMAVDTDEVYMTTKLAGKNTFFLPFNKGFNFGKGNPINPHGHKTA  254

Query  235   YLWKETLSKDGLTDILENYAQVVEEKDEKTGKKRYKQIFPRYHQLKVVRMLLANAAESGI  294
             YLW+E + K+++++I++++ ++      + +K+    +FPRYHQ+ VVR L+ + + +G+
Sbjct  255   YLWQEVFRKESIANIIQHFIRLDGSSKKQLDKR--TLFFPRYHQMDVVRRLVDHCSVNGV  312

Query  295   GRRYLIQHSAGSGKSNSIAWLAHQLV----------GLEHESKALFDSVIVVTDRRVLDK  344
             G+ YLIQHSAGSGKSNSI+W A QL+          G      +LFDSVIVVTDRR+LDK
Sbjct  313   GQTYLIQHSAGSGKSNSITWAAYQLIETYPISDDLPGSRGKEVPLFDSVIVVTDRRLLDK  372

Query  345   QIRDTIKQFAQVSATVGHAEHSGDLRKFLKAGKKIIITTVQKFPFILDEIGDEHRQSKFA  404
             Q+RD IK+F++V   V+ A  S++L+  L  GKKIIITT+QKFP+I+D I+D   + +FA
Sbjct  373   QLRDNIKEFSEVKNIVAPAFKSSELKSALENGKKIIITTIQKFPYIVDGIAD-LSDRRFA  431

Query  405   IIIDEAHSSQGGKTTAAMNRVLEETAPYGGSDDEGEETVEDKINKIMEGRKMVTNASYFA  464
             +IIDEAHSSQ+G         L+E+  + + D      V DK  +    RKM +NASYFA
Sbjct  432   VIIDEAHSSQDGHNQDK----LNEAMGFVSED------VLDKALQSAKNRKMRSNASYFA  481

Query  465   FTATPKNKTLEIFGEPNPQPDGTVKHHPFHSYTMKQAIQEGFILDVLKNYTPVESYYRLA  524
             FTATPKN TLE FG+   Q+DGT    PFH Y+MKQAI+EGFILDV+ NYT   SYY + 
Sbjct  482   FTATPKNTTLEKFGQR--QADGT--YVPFHLYSMKQAIEEGFILDVIANYTTYKSYYEIE  537

Query  525   KTVEDDPLFDANKAQKKLRRYVESHEHAIREKAEIMVDHFHAQVIGHRKIGGHARAMVIT  584
             K+++D+P FD++KAQK+LR YVE+ +++I  KAEIM++HF  +V+  +K+ G +++MV+T
Sbjct  538   KSIQDNPEFDSKKAQKRLRAYVEASQETIDTKAEIMLEHFIKHVVNGKKLKGKGKGMVVT  597

Query  585   NGIERAIQYFHAFKDYLKERKSPYAPIVAFSGEHEYGGKKVTEATLNGFPSSQ-------  637
             + IE AI+Y++A+   L+   +P+   +AFSG  E +G   TEA +NGFP ++       
Sbjct  598   QNIESAIRYYRALTIQLNKMGNPFKVAIAFSGSKEVDGIEYTEADINGFPEGDTKDYFDV  657

Query  638   ----------IPDKVQQGPYRFLIVADKFQTGYDEPLLHTMYVDKALSGIKAVQTLSRLN  687
                       IP  V+Q++YR+L+VA+K+ TG+D+P L +MYVDK L+++  VQ+LSRLN
Sbjct  658   NYKRKEPDSPIPKHVDQDAYRLLVVANKYLTGFDQPKLCAMYVDKKLASVLCVQALSRLN  717

Query  688   RAHP----QKHDTFVLDFYNDSETIQKSFEPYYRTTILSDETDPNKLHDLKSDLDGYQVY  743
             R+ P    + +D FVLDF+N  + I+ +F+P+Y +T LS+ TD N LH+LK D+D+  VY
Sbjct  718   RSAPKYGKKTEDLFVLDFFNSVDDIKTAFDPFYTSTTLSEATDVNVLHELKDDMDDTGVY  777

Query  744   SQAQIDDLVGLYLNGADRDKLDPILDACVATYNADLDEDGQ--VDFKGKAKAFVRTYGFL  801
                +++++   +++G + + L PI+D   A +N +L+ + +  VDFK KAK FV+ YG +
Sbjct  778   EWFEVEEFNKRFFEGREAQDLSPIIDIAAARFNHELELENEFKVDFKVKAKQFVKIYGQI  837

Query  802   SSILAYSNADWEKLSIFLNFLIPKLPA--PKEEDLSRGILEAIDMDSYRVE-VKTSLKIG  858
             +SI++Y   +WEKL  FL+FLIPKL+   P  E L  ++L+++D+ SY ++ VK +  I 
Sbjct  838   ASIMPYEVVQWEKLFWFLKFLIPKLSVEDPDKEALD-SLLDSVDLSSYGLQRVKLNHSIE  896

Query  859   LPDQDAEIGP-VPTSGGGRKPEPELDQLSNIIKAFNDQFGNIEWKDGDKIRKVIAEEIPA  917
             L D ++E++P  P + G+  PE+E D L +IIK FN++  +  W      ++V   +I+ 
Sbjct  897   LDDSETELDPQNPNPRGAYGPEAEKDPLDEIIKIFNERWFQ-GWSATPEEQRVKFVNIAE  955

Query  918   KVAADAAYQNAMKNNDKKTAR-IEHDAALQRVMIDLLSDHTELFKQFSDNPSFK-KW  972
              +  ++ ++   +NN    +R +  +  L+ +M++   D+ EL+K F+++P+FK  W
Sbjct  956   SIRNHPDFEAKYQNNADPHTRELAFEKMLKEIMLQRRKDELELYKLFAQDPAFKASW  1012

58) Dde_1859 in NC_007519


> EU272902|14|G13|167832520|ACA01830.1|Vibrio_cholerae_Amazonia_3509|-|13968..17036|-|VPI2_0013c|type 
I restriction enzyme 
HsdR
Length=1022

 Score =  619 bits (2339),  Expect = 2e-178, Method: Compositional matrix adjust.
 Identities = 422/1017 (42%), Positives = 657/1017 (65%), Gaps = 68/1017 (6%)

Query  5     DTSEKGLESIIVASLV--------EDAGYVQGDPQDYDREHAVDLAKLLQFLAATQPDTY  56
              + EKGL +I    L         ++  Y+ G P D+D++ A+D   + QFL  TQ+   
Sbjct  15    AAIEKGLAGICKEELALGEAPLNYNNDLYLIGSPSDFDKQYALDTRLFWQFLEDTQASEL  74

Query  57    EALGIDEEGPKRTQFLHRLQGEIAKRGVVDVLRGGIKHGPAHVDLFYGTP-TPGNVKAAE  115
             E L        + ++L+R++  I ++GV+ +L+ G+  + A + L Y +P ++++ K   
Sbjct  75    EKLKRTSPHDWQRKILERFDRMIMRHGVLRLLKKGLDVDDAFLSLMYPAPLASSSEKVKK  134

Query  116   RFAANIFSVTRQLRYSRNETALSLDMAVFINGLPIATFELKNKLTKQ-TVLDAVQQYQRD  174
              F+AN+FSVTRQ+ YS  +    +DM +FING+P+ T+ELKN  T Q +V ++ +QY+ D
Sbjct  135   DFSANLFSVTRQVCYSNANPLEEIDMVLFINGIPLITLELKNPWTGQNAVYHGQKQYRDD  194

Query  175   RDPKELLFQFGRCAVHFAVDDHEVRFCTHLKGKGSWFLPFDKGYNDGAGNPPNPAGLATD  234
             RD+++ L++F+RC VH AVD +EV   T L GK + FLPF+KG+N G GNP NP G  T 
Sbjct  195   RDANQPLLNFARCLVHMAVDTDEVYMTTKLAGKNTFFLPFNKGFNFGKGNPINPHGHKTA  254

Query  235   YLWKETLSKEGLTDILENYAQVVEEKDEKTGKKRYKQIFPRYHQLKVVRMLLANAAESGI  294
             YLW+E + KE++++I++++ ++      + +K+    +FPRYHQ+ VVR L+ + + +G+
Sbjct  255   YLWQEVFRKESIANIIQHFIRLDGSSKKQLDKR--TLFFPRYHQMDVVRRLVDHCSVNGV  312

Query  295   GRRYLIQHSAGSGKSNSIAWLAHQLV----------GLEHESKALFDSVIVVTDRRVLDK  344
             G+ YLIQHSAGSGKSNSI+W A QL+          G      +LFDSVIVVTDRR+LDK
Sbjct  313   GQTYLIQHSAGSGKSNSITWAAYQLIETYPISDDLPGSRGKEVPLFDSVIVVTDRRLLDK  372

Query  345   QIRDTIKQFAQVSATVGHAEHSGDLRKFLKAGKKIIITTVQKFPFILDEIGDEHRKSKFA  404
             Q+RD IK+F++V   V+ A  S++L+  L  GKKIIITT+QKFP+I+D I+D   + +FA
Sbjct  373   QLRDNIKEFSEVKNIVAPAFKSSELKSALENGKKIIITTIQKFPYIVDGIADLSDR-RFA  431

Query  405   IIIDEAHSSQGGKTTAAMNRVLEETAPYGGSDDEEEETVEDKINKIMEGRKMVTNASYFA  464
             +IIDEAHSSQ+G         L+E+  + + D      V DK  +    RKM +NASYFA
Sbjct  432   VIIDEAHSSQDGHNQDK----LNEAMGFVSED------VLDKALQSAKNRKMRSNASYFA  481

Query  465   FTATPKNKTLEIFGEPDPQPDGTVKHHPFHSYTMKQAIQEGFILDVLKNYTPVESYYRLA  524
             FTATPKN TLE FG+   Q+DGT    PFH Y+MKQAI+EGFILDV+ NYT   SYY + 
Sbjct  482   FTATPKNTTLEKFGQR--QADGT--YVPFHLYSMKQAIEEGFILDVIANYTTYKSYYEIE  537

Query  525   KTVEDDPLFDANKAQKKLRRYVESHEHAIREKAEIMVDHFHAQVIGHRKIGGHARAMVIT  584
             K+++D+P FD++KAQK+LR YVE+ +++I  KAEIM++HF  +V+  +K+ G +++MV+T
Sbjct  538   KSIQDNPEFDSKKAQKRLRAYVEASQETIDTKAEIMLEHFIKHVVNGKKLKGKGKGMVVT  597

Query  585   NGIERAIQYFHAFRDYLKERKSPYAPIVAFSGEHEYGGKKVTESTLNGF-----------  633
             + IE AI+Y++A+   L+   +P+   +AFSG  E +G   TE+ +NGF           
Sbjct  598   QNIESAIRYYRALTIQLNKMGNPFKVAIAFSGSKEVDGIEYTEADINGFPEGDTKDYFDV  657

Query  634   ------PSSQIPDKVQQDPYRFLIVADKFQTGYDEPLLHTMYVDKALSGIKAVQTLSRLN  687
                   P S IP  V+QD+YR+L+VA+K+ TG+D+P L +MYVDK L+++  VQ+LSRLN
Sbjct  658   NYKRKEPDSPIPKHVDQDAYRLLVVANKYLTGFDQPKLCAMYVDKKLASVLCVQALSRLN  717

Query  688   RAHP----QKHDTFVLDFYNDSETIQRSFEPYYRTTILSDETDPNKLHDLKSDLDGYQVY  743
             R+ P    + +D FVLDF+N  + I+ +F+P+Y +T LS+ TD N LH+LK D+D+  VY
Sbjct  718   RSAPKYGKKTEDLFVLDFFNSVDDIKTAFDPFYTSTTLSEATDVNVLHELKDDMDDTGVY  777

Query  744   SQVQIDDLVGLYLNGADRDKLDPILDACVATYNADLDEDGQ--VDFKGKAKAFVRTYGFL  801
                +++++   +++G + + L PI+D   A +N +L+ + +  VDFK KAK FV+ YG +
Sbjct  778   EWFEVEEFNKRFFEGREAQDLSPIIDIAAARFNHELELENEFKVDFKVKAKQFVKIYGQI  837

Query  802   SSILAYSNADWEKLSIFLNFLIPKLPA--PKEEDLSRGILEAIDMDSYRVE-VKTSLKIG  858
             +SI++Y   +WEKL  FL+FLIPKL+   P  E L  ++L+++D+ SY ++ VK +  I 
Sbjct  838   ASIMPYEVVQWEKLFWFLKFLIPKLSVEDPDKEALD-SLLDSVDLSSYGLQRVKLNHSIE  896

Query  859   LPDQDAEIGPVPTTGSGR-KPEPELDQLSNIIKAFNDQFGNIDWKDGDKIRKVIAEEIPA  917
             L D ++E++P      G   PE+E D L +IIK FN++  + +W      ++V   +I+ 
Sbjct  897   LDDSETELDPQNPNPRGAYGPEAEKDPLDEIIKIFNERWFQ-GWSATPEEQRVKFVNIAE  955

Query  918   KVAADAAYQNAMKNNDKKTAR-IEHDAALQRVMIDLLSDHTELFKQFSDNPSFK-KW  972
              +  ++ ++   +NN    +R +  +  L+ +M++   D+ EL+K F+++P+FK  W
Sbjct  956   SIRNHPDFEAKYQNNADPHTRELAFEKMLKEIMLQRRKDELELYKLFAQDPAFKASW  1012

59) DGo_CA2781 in NC_017790


> EU272902|14|G13|167832520|ACA01830.1|Vibrio_cholerae_Amazonia_3509|-|13968..17036|-|VPI2_0013c|type 
I restriction enzyme 
HsdR
Length=1022

 Score =  619 bits (2337),  Expect = 3e-178, Method: Compositional matrix adjust.
 Identities = 401/988 (41%), Positives = 659/988 (67%), Gaps = 60/988 (6%)

Query  26    GDPHDYEREYAVDLAQLTAFLEATQPKLVEALDLRAASPTRHKFLSRLQGEITKRGVVHV  85
             G P D++++YA+D   +  FLE TQ+  +E L   ++   ++K+L R++  I ++GV+++
Sbjct  46    GSPSDFDKQYALDTRLFWQFLEDTQASELEKLKRTSPHDWQRKILERFDRMIMRHGVLRL  105

Query  86    LRHGVAHGAHHVDLFYGTP-TPGNAKAAALHTLNHFSVTRQLRYSRSETALALDVGLFVN  144
             L+ G+  +   + L Y +P ++++ K     + N FSVTRQ+ YS ++    +D+ LF+N
Sbjct  106   LKKGLDVDDAFLSLMYPAPLASSSEKVKKDFSANLFSVTRQVCYSNANPLEEIDMVLFIN  165

Query  145   GLPVATMELKNSLTKQ-TVADAVEQYRRDRDPRELLFAMGRCVAHFAVDDAEVRFCTELK  203
             G+P+ T+ELKN+ T Q +V ++  QYR DRD+ + L+  +RC+ H AVD  EV   T L 
Sbjct  166   GIPLITLELKNPWTGQNAVYHGQKQYRDDRDANQPLLNFARCLVHMAVDTDEVYMTTKLA  225

Query  204   GKASWFLPFDRGWQEGAGNPPNPNGLKTAYFWEEILTPASLTDILENYAQVVEEEHPKTK  263
             GK + FLPF++G + G GNP NP+G KTAY+W+E++   S+++I++++ ++  +  +K +
Sbjct  226   GKNTFFLPFNKGFNFGKGNPINPHGHKTAYLWQEVFRKESIANIIQHFIRL--DGSSKKQ  283

Query  264   KKKRRQIFPRYHQLDVVRKLLVDARERGAGQRYLIQHSAGSGKSNSIAWLAHQLV-----  318
               KR  +FPRYHQ+DVVR+L+ +    G GQ YLIQHSAGSGKSNSI+W A QL+     
Sbjct  284   LDKRTLFFPRYHQMDVVRRLVDHCSVNGVGQTYLIQHSAGSGKSNSITWAAYQLIETYPI  343

Query  319   -----GLEQAGQAVFDSVVVVTDRRILDKQIRDTIRQFAQVGATVGHATHSGELRQFLES  373
                  G      ++FDSV+VVTDRR+LDKQ+RD I++F++V   V+ A  S+EL+  LE+
Sbjct  344   SDDLPGSRGKEVPLFDSVIVVTDRRLLDKQLRDNIKEFSEVKNIVAPAFKSSELKSALEN  403

Query  374   GKKIIITTVQKFPFILDEIEGMGKGRTFAILIDEAHSSQSGRSAAAMNEALAGSDDANDQ  433
             GKKIIITT+QKFP+I+D I +++ +R FA++IDEAHSSQ G++   +NEA++        
Sbjct  404   GKKIIITTIQKFPYIVDGIADLS-DRRFAVIIDEAHSSQDGHNQDKLNEAMG--------  454

Query  434   ELEPEDLINSVLECRMKARKMLGNASYFAFTATPKNKTLETFGRAAPAGEKVPHLPFHLY  493
              + +ED+++  L+   K RKM +NASYFAFTATPKN TLE FG+  + G     +PFHLY
Sbjct  455   -FVSEDVLDKALQS-AKNRKMRSNASYFAFTATPKNTTLEKFGQRQADG---TYVPFHLY  509

Query  494   SMKQAIQEGFIQDVLRAYTPVESYYRLVKTVDADPEFDTKKAQKKLRAYVEGHEHAIRLK  553
             SMKQAI+EGFI DV+  YT   SYY + K+++ +PEFD+KKAQK+LRAYVE+ +++I  K
Sbjct  510   SMKQAIEEGFILDVIANYTTYKSYYEIEKSIQDNPEFDSKKAQKRLRAYVEASQETIDTK  569

Query  554   AEIMVDHFHEQVLAIQKVGGQARAMIVTGSVARALDYFHAVKAYLEQRKSPYKAIVAFSG  613
             AEIM++HF  +V+  +K+ G++++M+VT ++  A+ Y++A+   L++  +P+K  +AFSG
Sbjct  570   AEIMLEHFIKHVVNGKKLKGKGKGMVVTQNIESAIRYYRALTIQLNKMGNPFKVAIAFSG  629

Query  614   EPEYKGIKVTEASLNGFASND-----------------IPDKIQEEPYRFLICADKFQTG  656
               E  GI  TEA +NGF+  D                 IP  +++++YR+L+ A+K+ TG
Sbjct  630   SKEVDGIEYTEADINGFPEGDTKDYFDVNYKRKEPDSPIPKHVDQDAYRLLVVANKYLTG  689

Query  657   YDEPLLHTMYVDKPLSGIKAVQTLSRLNRAHP----QKHDVFVLDFQNSTEVIRQSFDAY  712
             +D+P L +MYVDK L+++  VQ+LSRLNR+ P    + +D+FVLDF NS + I+ +FD++
Sbjct  690   FDQPKLCAMYVDKKLASVLCVQALSRLNRSAPKYGKKTEDLFVLDFFNSVDDIKTAFDPF  749

Query  713   YRATLLSDETDPNRLHDLKSDLDSAQVYSPGQVENLVELYLAGADRDRLDPILDVCVATY  772
             Y +T LS+ TD N LH+LK D+D + VY   +VE++   ++ G + + L PI+D+  A +
Sbjct  750   YTSTTLSEATDVNVLHELKDDMDDTGVYEWFEVEEFNKRFFEGREAQDLSPIIDIAAARF  809

Query  773   N---DLDEDAQVAFKGGAKTFVRTYSFLAALVPYTTAAWEQLSIFLTFLIPKLPA--PKE  827
             N   +L+++ +V FK  AK FV+ Y+ +A+++PY    WE+L  FL FLIPKL+   P  
Sbjct  810   NHELELENEFKVDFKVKAKQFVKIYGQIASIMPYEVVQWEKLFWFLKFLIPKLSVEDPDK  869

Query  828   EDLAQGILDSIDMESYRVEKQTVT-KIQLTDADAELDP-VPVMAGGATPDPELERLSNIV  885
             E L +++LDS+D+ SY +++  +   I+L D+++ELDP  P   G+  P++E + L +I+
Sbjct  870   EAL-DSLLDSVDLSSYGLQRVKLNHSIELDDSETELDPQNPNPRGAYGPEAEKDPLDEII  928

Query  886   KIFNDQFGNIAWTDADRLHKLITEEIPDLVARDAAYQNALKNSDRQNAR-IEHDRALMRV  944
             KIFN++  + +W+ +   +++   +I++ +  ++ ++   +N+   ++R +  ++ L  +
Sbjct  929   KIFNERWFQ-GWSATPEEQRVKFVNIAESIRNHPDFEAKYQNNADPHTRELAFEKMLKEI  987

Query  945   LIGLMRDNTELFKQYSDNGSFQ-RWMQD  971
             ++   +D+ EL+K ++++ +F+  W Q 
Sbjct  988   MLQRRKDELELYKLFAQDPAFKASWTQS  1015

60) MM_2976 in NC_003901


> EU272902|14|G13|167832520|ACA01830.1|Vibrio_cholerae_Amazonia_3509|-|13968..17036|-|VPI2_0013c|type 
I restriction enzyme 
HsdR
Length=1022

 Score =  615 bits (2324),  Expect = 3e-177, Method: Compositional matrix adjust.
 Identities = 413/1032 (41%), Positives = 688/1032 (67%), Gaps = 61/1032 (5%)

Query  1     MTTDTTEKGLETLIVEAMTGTKPDPAQTDMGREPSAL-YGVTGWILGRWQDYDREYAVDL  59
             M + T E++LE+ I  +++G      + +++   ++L Y     ++G   D+D++YA+D 
Sbjct  4     MVSKTNEQALEAAIEKGLAGI----CKEELALGEAPLNYNNDLYLIGSPSDFDKQYALDT  59

Query  60    VQLTEFLKSTQPEVAESLDLENASPTRQKFLARLQGEVAKRGIIEVLRNGLKHGKYDIDL  119
               + +FL  TQ+   E L   ++   ++K+L R++  + ++G++ +L++GL  +   + L
Sbjct  60    RLFWQFLEDTQASELEKLKRTSPHDWQRKILERFDRMIMRHGVLRLLKKGLDVDDAFLSL  119

Query  120   FYGTP-TPGNTKAEERYALNRFSVTRQLRYSRGETQLALDLCLFINGLPVATFELKNSLT  178
              Y +P ++++ K    ++ N FSVTRQ+ YS ++    +D+ LFING+P+ T+ELKN+ T
Sbjct  120   MYPAPLASSSEKVKKDFSANLFSVTRQVCYSNANPLEEIDMVLFINGIPLITLELKNPWT  179

Query  179   KQ-TVEDAVEQYKRDRDSRELLFQFGRCMVHFAVDDHEVKFCTQLNGKNSWFLPFNQGYN  237
              Q +V ++  QY+ DRD+ + L++F+RC+VH AVD +EV   T+L GKN+ FLPFN+G+N
Sbjct  180   GQNAVYHGQKQYRDDRDANQPLLNFARCLVHMAVDTDEVYMTTKLAGKNTFFLPFNKGFN  239

Query  238   DGTGNPPNPAGIKTDYLWKKILTPQGLTDILENYAQvveekdektgkkkkvQIFPRYHQL  297
              G GNP NP G KT YLW+ ++  +++++I++++ ++      + +K+    +FPRYHQ+
Sbjct  240   FGKGNPINPHGHKTAYLWQEVFRKESIANIIQHFIRLDGSSKKQLDKRTL--FFPRYHQM  297

Query  298   DVVRKLLAHAEWHGAGMRYLVQHSAGSGKSNSIAWLAHQLI----------SLKKDDKEI  347
             DVVR+L+ H   +G G  YL+QHSAGSGKSNSI+W A QLI          + +  +  +
Sbjct  298   DVVRRLVDHCSVNGVGQTYLIQHSAGSGKSNSITWAAYQLIETYPISDDLPGSRGKEVPL  357

Query  348   FDSIIVITDRRVLDKQIRDTIKQFAQVGSTVGHAERSGDLRKFIESGKKIIISTVQKFPF  407
             FDS+IV+TDRR+LDKQ+RD IK+F++V + V+ A +S++L+  +E+GKKIII+T+QKFP+
Sbjct  358   FDSVIVVTDRRLLDKQLRDNIKEFSEVKNIVAPAFKSSELKSALENGKKIIITTIQKFPY  417

Query  408   ILDEIGNEHRGRKFAIIIDEAHSSQGGRTAAAMSEALSDSKDQKDPEDTINDALQKRMEA  467
             I+D I+ +  +R+FA+IIDEAHSSQ+G+    ++EA++       +ED ++ ALQ   + 
Sbjct  418   IVDGIA-DLSDRRFAVIIDEAHSSQDGHNQDKLNEAMGFV-----SEDVLDKALQSAKN-  470

Query  468   RKMLPNASYFAFTATPKNKTLELFGEPYKDGDKIKHRPFHNYTMKQAIQEGFILDVLRYY  527
             RKM +NASYFAFTATPKN TLE FG+   DG  +   PFH Y+MKQAI+EGFILDV+  Y
Sbjct  471   RKMRSNASYFAFTATPKNTTLEKFGQRQADGTYV---PFHLYSMKQAIEEGFILDVIANY  527

Query  528   TPVNSYYKLIKTVESDPEFDTKKAKKKLRKYVESHDYAIRLKAEIIVDHFQEQVIALNKI  587
             T  +SYY + K+++ +PEFD+KKA+K+LR YVE+ + +I  KAEI+++HF  +V+  +K+
Sbjct  528   TTYKSYYEIEKSIQDNPEFDSKKAQKRLRAYVEASQETIDTKAEIMLEHFIKHVVNGKKL  587

Query  588   GGQARAMVVTNGIERAIQYYHAIRDYLLELNSPYKAIVAFSGEHEYGGVKVTEATLNGFP  647
              G++++MVVT+ IE AI+YY+A+   L  + +P+K  +AFSG  E +G+  TEA +NGFP
Sbjct  588   KGKGKGMVVTQNIESAIRYYRALTIQLNKMGNPFKVAIAFSGSKEVDGIEYTEADINGFP  647

Query  648   SSQ-----------------IEDKIEEEPYRFLICADKFQTGYDEPLLHTMYVDKVLSGI  690
              ++                 I   +++++YR+L+ A+K+ TG+D+P L +MYVDK L+++
Sbjct  648   EGDTKDYFDVNYKRKEPDSPIPKHVDQDAYRLLVVANKYLTGFDQPKLCAMYVDKKLASV  707

Query  691   KAVQTLSRLNRAHP----KKHDVFVLDFMNDTDTIQDAFSDYYRTTVLSDETDPNKLHDL  746
               VQ+LSRLNR+ P    K +D+FVLDF N  D I+ AF  +Y +T LS+ TD N LH+L
Sbjct  708   LCVQALSRLNRSAPKYGKKTEDLFVLDFFNSVDDIKTAFDPFYTSTTLSEATDVNVLHEL  767

Query  747   KSDLDSYQAYSPEQIEQFVELYLGGADRDKLDPILDVCVATYKDHLDEDEQ--VDFKSKA  804
             K D+D    Y   ++E+F   ++ G + + L PI+D+  A ++++L+ +++  VDFK KA
Sbjct  768   KDDMDDTGVYEWFEVEEFNKRFFEGREAQDLSPIIDIAAARFNHELELENEFKVDFKVKA  827

Query  805   KAFSRTYGFLASILPYTNADWEKLSIFLNFLIPKLPA--PREEDLSKGILEAIDMDSYRV  862
             K F + YG +ASI+PY   +WEKL  FL+FLIPKL+   P  E L  ++L+++D+ SY +
Sbjct  828   KQFVKIYGQIASIMPYEVVQWEKLFWFLKFLIPKLSVEDPDKEALD-SLLDSVDLSSYGL  886

Query  863   EKQAVVN-IQLPDSDSEIEP-VPTEAGGFKPEPELDRLSNILKTFNDQ-FGNIRWTDSDR  919
             ++  + + I+L DS++E++P  P   G++ PE+E D L +I+K FN++ F    W+ +  
Sbjct  887   QRVKLNHSIELDDSETELDPQNPNPRGAYGPEAEKDPLDEIIKIFNERWFQG--WSATPE  944

Query  920   VHRLITEEIPARVAADVAYQNA-KKNSDKQNAKIEHDKALARVMIALMKDDTQLFKLFSD  978
              +R+   +I+  +  +  ++   ++N+D +   +  +K L  +M+   KD+ +L+KLF++
Sbjct  945   EQRVKFVNIAESIRNHPDFEAKYQNNADPHTRELAFEKMLKEIMLQRRKDELELYKLFAQ  1004

Query  979   NESFRRTLTDAI  990
             + +F+ + T+++
Sbjct  1005  DPAFKASWTQSM  1016

61) Nwat_0200 in NC_014315


> EU272902|14|G13|167832520|ACA01830.1|Vibrio_cholerae_Amazonia_3509|-|13968..17036|-|VPI2_0013c|type 
I restriction enzyme 
HsdR
Length=1022

 Score =  614 bits (2319),  Expect = 8e-177, Method: Compositional matrix adjust.
 Identities = 431/988 (44%), Positives = 656/988 (67%), Gaps = 47/988 (4%)

Query  25    YVQGDPQDFDREHAVDRAKLVQFLAATQPDTFENLGIEQDSPKRTQFLHRLQGEIAKRGV  84
             Y+ G P DFD++ A+D   + QFL  TQ+  +E+L        + ++L+R++  I ++GV
Sbjct  43    YLIGSPSDFDKQYALDTRLFWQFLEDTQASELEKLKRTSPHDWQRKILERFDRMIMRHGV  102

Query  85    IDVLRGGLKHGPAHIDLFYGTP-TPGNVKAAERFAANLFSVTRQLRYSRVGTALSLDLAV  143
             + +L+ GL  + A + L Y +P ++++ K    F+ANLFSVTRQ+ YS       +D+ +
Sbjct  103   LRLLKKGLDVDDAFLSLMYPAPLASSSEKVKKDFSANLFSVTRQVCYSNANPLEEIDMVL  162

Query  144   FINGLPIATFELKNKLTKQ-TVLDAVQQYQRDRDPKEPLFQFGRCVVHFAMDDHEVRMCT  202
             FING+P+ T+ELKN  T Q +V ++ +QY+ DRD+++PL++F+RC+VH A+D +EV M T
Sbjct  163   FINGIPLITLELKNPWTGQNAVYHGQKQYRDDRDANQPLLNFARCLVHMAVDTDEVYMTT  222

Query  203   HLKGKGSWFLPFNKGYNDGAGNPPNPHGLATDYLWKEILTKEGLVDILENYAQVVeekde  262
              L GK + FLPFNKG+N G GNP NPHG  T YLW+E++ KE++ +I++++ ++  +   
Sbjct  223   KLAGKNTFFLPFNKGFNFGKGNPINPHGHKTAYLWQEVFRKESIANIIQHFIRL--DGSS  280

Query  263   ktgkkkdkQIFPRYHQLKVVRRLLAHARKSGVGKRYLIQHSAGSGKSNSIAWLAHQLVGL  322
             K    K   +FPRYHQ+ VVRRL+ H   +GVG+ YLIQHSAGSGKSNSI+W A QL+  
Sbjct  281   KKQLDKRTLFFPRYHQMDVVRRLVDHCSVNGVGQTYLIQHSAGSGKSNSITWAAYQLIET  340

Query  323   ------EQGGRA----LFDSVIVVTDRRVLDKQIRDTIKQFVQVSATVGHAEHSGDLRKF  372
                     G+R+    LFDSVIVVTDRR+LDKQ+RD IK+F +V   V+ A  S++L+  
Sbjct  341   YPISDDLPGSRGKEVPLFDSVIVVTDRRLLDKQLRDNIKEFSEVKNIVAPAFKSSELKSA  400

Query  373   LKVGKKIIITTVQKFPFILDEIGDEHRGAKFAIVIDEAHSSQGGKTTAAMNRVLEETAPY  432
             L  GKKIIITT+QKFP+I+D I+D   + +FA++IDEAHSSQ+G         L+E+  +
Sbjct  401   LENGKKIIITTIQKFPYIVDGIAD-LSDRRFAVIIDEAHSSQDGHNQDK----LNEAMGF  455

Query  433   GDEMASVEDKINQIMESRKMVTNASYFAFTATPKNKTLEIFGEPDPQPDGTVKHSPFHSY  492
               E   V DK  Q   +RKM +NASYFAFTATPKN TLE FG+   Q+DGT    PFH Y
Sbjct  456   VSE--DVLDKALQSAKNRKMRSNASYFAFTATPKNTTLEKFGQR--QADGT--YVPFHLY  509

Query  493   TMKQAIQEGFILDVLKHYTPVESYYQLVKAVEDDPLFDANKAQKELRRYVESHAHAVRAK  552
             +MKQAI+EGFILDV+ +YT   SYY++ K+++D+P FD++KAQK LR YVE+  +++ +K
Sbjct  510   SMKQAIEEGFILDVIANYTTYKSYYEIEKSIQDNPEFDSKKAQKRLRAYVEASQETIDTK  569

Query  553   AEIMVDHFHAQVIGHRKIGGQARAMVVTHGIERAIQYFHAFKDYLKERKSPYAPIVAFSG  612
             AEIM++HF  +V+  +K+ G++++MVVT+ IE AI+Y++A+   L+   +P+   +AFSG
Sbjct  570   AEIMLEHFIKHVVNGKKLKGKGKGMVVTQNIESAIRYYRALTIQLNKMGNPFKVAIAFSG  629

Query  613   EHDDPAWS-GGGRLQGAPQYGGKKVTEAALN-GFPGSQIPDKIQQDPYRFLIVADKYQTG  670
               +  +     + ++G P+ + K   +   +   P+S IP  ++QD+YR+L+VA+KY TG
Sbjct  630   SKEVDGIEYTEADINGFPEGDTKDYFDVNYKRKEPDSPIPKHVDQDAYRLLVVANKYLTG  689

Query  671   YDEPLLHTLYVDKALSGIKAVQTLSRLNRAHP----QKHDTFVLDFCNDSDTIQQSFEPY  726
             +D+P L ++YVDK L+++  VQ+LSRLNR+ P    + +D FVLDF N  D I+ +F+P+
Sbjct  690   FDQPKLCAMYVDKKLASVLCVQALSRLNRSAPKYGKKTEDLFVLDFFNSVDDIKTAFDPF  749

Query  727   YRATLLSDETDPNKLHDLKSDLDDYQVYSQAQIDDLVGRYLSGADRDQLDPILDVCATTY  786
             Y +T LS+ TD N LH+LK D+DD  VY   +++++  R++ G + ++L PI+D+ A+ +
Sbjct  750   YTSTTLSEATDVNVLHELKDDMDDTGVYEWFEVEEFNKRFFEGREAQDLSPIIDIAAARF  809

Query  787   NADLDEDGQ--VDFKGKAKSFVRTYGFLASILPYSNAGWEKLSILLNFLIPKLPA--PRE  842
             N +L+ + +  VDFK KAK FV+ YG +ASI+PY    WEKL  +L+FLIPKL+   P  
Sbjct  810   NHELELENEFKVDFKVKAKQFVKIYGQIASIMPYEVVQWEKLFWFLKFLIPKLSVEDPDK  869

Query  843   EDLSWGILETVDMDSYRVE-ARSSLKIGLADQEVEIGP-VPTSGGGRKSEPELDQLSNII  900
             E L  ++L++VD+ SY ++  + +  I L D E E++P  P + G+  +E+E D L +II
Sbjct  870   EALD-SLLDSVDLSSYGLQRVKLNHSIELDDSETELDPQNPNPRGAYGPEAEKDPLDEII  928

Query  901   KAFNDQFGNIEWKDADKIRKV----IAEEILIKVSMDLAYQNAMKNNDKKTARIEHDAAL  956
             K FN++  +  W  +   ++V    IAE I      +  YQN   N D  T  +  +  L
Sbjct  929   KIFNERWFQ-GWSATPEEQRVKFVNIAESIRNHPDFEAKYQN---NADPHTRELAFEKML  984

Query  957   QRVMIDLLADHTELYKQFSDNPSFK-KW  983
             + +M++   D+ ELYK F+++P+FK  W
Sbjct  985   KEIMLQRRKDELELYKLFAQDPAFKASW  1012

62) Mhar_1856 in NC_017527


> EU272902|14|G13|167832520|ACA01830.1|Vibrio_cholerae_Amazonia_3509|-|13968..17036|-|VPI2_0013c|type 
I restriction enzyme 
HsdR
Length=1022

 Score =  611 bits (2308),  Expect = 6e-176, Method: Compositional matrix adjust.
 Identities = 411/995 (42%), Positives = 664/995 (67%), Gaps = 60/995 (6%)

Query  25    YVEGDSKDYDRDHAVDLIKLLEFLLSTQPQAVNQLGLDGEGLKLQQFLARLQGEIAKRGV  84
             Y+ G + D+D++ A+D   + +FL  TQ+  +++L   +     +++L R++  I ++GV
Sbjct  43    YLIGSPSDFDKQYALDTRLFWQFLEDTQASELEKLKRTSPHDWQRKILERFDRMIMRHGV  102

Query  85    IDVLRNGINHGPAHIDVFYGTP-SPGNLKAAELFAANVFSVTRQLHYSKDETQLAFDLCL  143
             + +L++G++ + A + + Y +P ++++ K    F+AN+FSVTRQ+ YS+ +    +D+ L
Sbjct  103   LRLLKKGLDVDDAFLSLMYPAPLASSSEKVKKDFSANLFSVTRQVCYSNANPLEEIDMVL  162

Query  144   FINGLPIATFELKNSLTKQ-TVEDAVQQYKRDRNPRELLFQFGRCAVHFAVDDHEVRMCT  202
             FING+P+ T+ELKN+ T Q +V ++ +QY+ DR++ + L++F+RC VH AVD +EV M T
Sbjct  163   FINGIPLITLELKNPWTGQNAVYHGQKQYRDDRDANQPLLNFARCLVHMAVDTDEVYMTT  222

Query  203   HLQGKSSWFLPFNKGYDDGAGNPPNPNGIKTDYLWREILTREGLTDILETYAQVVQKKNE  262
              L GK++ FLPFNKG++ G GNP NP+G KT YLW+E++ +E++++I++ + ++    + 
Sbjct  223   KLAGKNTFFLPFNKGFNFGKGNPINPHGHKTAYLWQEVFRKESIANIIQHFIRLDGSSKK  282

Query  263   KTGRKKLEQIFPRYHQLDVVRKLLASAQHRGAGKRYLIQHSAGSGKSNSIAWLAHQLIGL  322
             + +++ L  +FPRYHQ+DVVR+L+      G G+ YLIQHSAGSGKSNSI+W A QLI  
Sbjct  283   QLDKRTL--FFPRYHQMDVVRRLVDHCSVNGVGQTYLIQHSAGSGKSNSITWAAYQLIET  340

Query  323   --------ERDGKTI--FDSIIVVTDRRVLDKQIKDTIKQFAQVSATVGHAERSADLRQY  372
                        GK +  FDS+IVVTDRR+LDKQ++D IK+F++V   V+ A +S++L+  
Sbjct  341   YPISDDLPGSRGKEVPLFDSVIVVTDRRLLDKQLRDNIKEFSEVKNIVAPAFKSSELKSA  400

Query  373   LAGGKKIIITTVQKFPVVLKAIGDEHRGHSFAIIIDEAHSSQGGRTSAKMSMVLSKEGGE  432
             L  GKKIIITT+QKFP ++ +I+D   ++ FA+IIDEAHSSQ+G+   K++  ++     
Sbjct  401   LENGKKIIITTIQKFPYIVDGIAD-LSDRRFAVIIDEAHSSQDGHNQDKLNEAMGF----  455

Query  433   KEAETPEDRINRIMES---RKMLSNASYFAFTATPKNKTLEIFGEAYMEGDDVKHRPFHS  489
                  +ED +++ ++S   RKM SNASYFAFTATPKN TLE FG+   +G  V   PFH 
Sbjct  456   ----VSEDVLDKALQSAKNRKMRSNASYFAFTATPKNTTLEKFGQRQADGTYV---PFHL  508

Query  490   YTMKQAIQEGFILDVLKNYTPVDSYYRLVKKVEDDPEFDTKKAQKKLRRYVEHNEHAIKM  549
             Y+MKQAI+EGFILDV+ NYT   SYY + K ++D+PEFD+KKAQK+LR YVE ++++I  
Sbjct  509   YSMKQAIEEGFILDVIANYTTYKSYYEIEKSIQDNPEFDSKKAQKRLRAYVEASQETIDT  568

Query  550   KAEIMVDHFHDQVLAKKKIGGQARAMVITSGIALAIEYYHAISNYLIERKSPWQAIVAFS  609
             KAEIM++HF  +V+  KK+ G++++MV+T  I  AI YY+A++  L    +P +  +AFS
Sbjct  569   KAEIMLEHFIKHVVNGKKLKGKGKGMVVTQNIESAIRYYRALTIQLNKMGNPFKVAIAFS  628

Query  610   GEHEYGGQNVTEASLNGFASNKIPETF-----------------QDEPYRFLVVAEKFQT  652
             G  E +G + TEA +NGF+     + F                 ++++YR+LVVA+K+ T
Sbjct  629   GSKEVDGIEYTEADINGFPEGDTKDYFDVNYKRKEPDSPIPKHVDQDAYRLLVVANKYLT  688

Query  653   GYDEPLLHTMYVDKPLSSIKAVQTLSRLNRAHP----QKHDTFVLDFFNDADTIMKAFEP  708
             G+D+P L +MYVDK L+S+  VQ+LSRLNR+ P    + +D FVLDFFN  D I  AF+P
Sbjct  689   GFDQPKLCAMYVDKKLASVLCVQALSRLNRSAPKYGKKTEDLFVLDFFNSVDDIKTAFDP  748

Query  709   YYRTTILSEETDPNKLHDLKADLDGYQVYNPQQVEHFVNLYLDGVDREKLDPILDTCVAT  768
             +Y +T LSE TD N LH+LK D+D+  VY+  +VE+F + +++G + + L PI+D   A 
Sbjct  749   FYTSTTLSEATDVNVLHELKDDMDDTGVYEWFEVEEFNKRFFEGREAQDLSPIIDIAAAR  808

Query  769   YNEQLDEDGQ--IDFKSKAKGFIRTYGFLASILPFTNAEWEKLSIFLNFLTPKLPA--PK  824
             +N++L+ + +  +DFK KAK F++ YG +ASI+P+   +WEKL  FL+FL PKL+   P 
Sbjct  809   FNHELELENEFKVDFKVKAKQFVKIYGQIASIMPYEVVQWEKLFWFLKFLIPKLSVEDPD  868

Query  825   EEDLSKGIIEAIDMDSYRVE-VRSSIDIILEDKDGVVDP-VPTSAGGHKPEPELDLLSNI  882
              E L  ++++++D+ SY ++ V+ +  I L+D +  +DP  P + G+  PE+E D L +I
Sbjct  869   KEALD-SLLDSVDLSSYGLQRVKLNHSIELDDSETELDPQNPNPRGAYGPEAEKDPLDEI  927

Query  883   IKAFNDQFGNIEWKDIDRIHKIISEEIPAKVSADKAYQNAMKNSDKQNAR-IEHDKALQR  941
             IK FN++  +  W      +++   +I+  +  +  ++   +N+   ++R +  +K L+ 
Sbjct  928   IKIFNERWFQ-GWSATPEEQRVKFVNIAESIRNHPDFEAKYQNNADPHTRELAFEKMLKE  986

Query  942   VIIELLNDQTELFKLFSDNPTFR-KWLSDMNFLVT  975
             ++++  +D+ EL+KLF+++P+F+  W   M+ +V 
Sbjct  987   IMLQRRKDELELYKLFAQDPAFKASWTQSMQRMVG  1021

63) DESAM_20023 in NC_020055


> EU272902|14|G13|167832520|ACA01830.1|Vibrio_cholerae_Amazonia_3509|-|13968..17036|-|VPI2_0013c|type 
I restriction enzyme 
HsdR
Length=1022

 Score =  607 bits (2292),  Expect = 1e-174, Method: Compositional matrix adjust.
 Identities = 417/987 (43%), Positives = 650/987 (66%), Gaps = 60/987 (6%)

Query  25    YSEGAPQDYDRSHAVDLIKLTNFIEATQPEVADRLSLKVDSPTRTKFLHRLQGEIAKRGI  84
             Y  G+P D+D+  A+D   + +F+E TQ+   ++L        + K+L+R++  I ++G+
Sbjct  43    YLIGSPSDFDKQYALDTRLFWQFLEDTQASELEKLKRTSPHDWQRKILERFDRMIMRHGV  102

Query  85    IDVLRKGVKHGPDSVTLFYGSP-TAKNEKARELFDQNIFSVTRQLRYSNSNTQLALDMGI  143
             + +L+KG+  +   ++L Y +P ++ +EK +  F  N+FSVTRQ+ YSN+N    +DM +
Sbjct  103   LRLLKKGLDVDDAFLSLMYPAPLASSSEKVKKDFSANLFSVTRQVCYSNANPLEEIDMVL  162

Query  144   FINGLPVATFELKNKLTKQ-TVHDAVQQYKNDRDPKELLFQFGRCMVHFVVDDHEVRMCT  202
             FING+P+ T+ELKN  T Q +V ++ +QY++DRD+++ L++F+RC+VH  VD +EV M T
Sbjct  163   FINGIPLITLELKNPWTGQNAVYHGQKQYRDDRDANQPLLNFARCLVHMAVDTDEVYMTT  222

Query  203   HLKGKASWFLPFNKGHNDGAGNPPNPAGLATDYLWKEILNKERLTDILENYAQVVEEKDE  262
              L GK + FLPFNKG N G GNP NP G  T YLW+E++ KE +++I++++ ++      
Sbjct  223   KLAGKNTFFLPFNKGFNFGKGNPINPHGHKTAYLWQEVFRKESIANIIQHFIRLDGSSKK  282

Query  263   KTGRKRYKQIFPRYHQLDVVRKLLSDVKKNGVGKRYLIQHSAGSGKSNSIAWLAHQLVGL  322
             + +++    +FPRYHQ+DVVR+L+ +   NGVG+ YLIQHSAGSGKSNSI+W A QL+  
Sbjct  283   QLDKR--TLFFPRYHQMDVVRRLVDHCSVNGVGQTYLIQHSAGSGKSNSITWAAYQLIET  340

Query  323   ---------EKDKN-PILDSIIVVTDRRVLDKQIRDTIRSFAQVGNVVGHADRSGDLRRF  372
                       ++K+ P++DS+IVVTDRR+LDKQ+RD I+ F++V N+V+ A +S++L+  
Sbjct  341   YPISDDLPGSRGKEVPLFDSVIVVTDRRLLDKQLRDNIKEFSEVKNIVAPAFKSSELKSA  400

Query  373   INEGKQIIITTVQKFPFILAEIGDDHRQNKFAIIIDEAHSSQGGRTASKMNMALsadvsd  432
             +++GK+IIITT+QKFP+I+  I+D   + +FA+IIDEAHSSQ+G+   K+N A++    D
Sbjct  401   LENGKKIIITTIQKFPYIVDGIAD-LSDRRFAVIIDEAHSSQDGHNQDKLNEAMGFVSED  459

Query  433   sdeeestedKINELMEGRKMLTNASYFAFTATPKNKTLEIFGEPSPQPDGKVKHY-PFQS  491
               +      K       RKM +NASYFAFTATPKN TLE FG+   Q+DG    Y PF+ 
Sbjct  460   VLDKALQSAK------NRKMRSNASYFAFTATPKNTTLEKFGQR--QADGT---YVPFHL  508

Query  492   YTMKQAIQEGFILDVLKNYTPVESFYRLSKTVEDDPLFDTKKAQKKLRKYVESNTHAIRE  551
             Y+MKQAI+EGFILDV+ NYT   S+Y + K+++D+P FD+KKAQK+LR YVE++ ++I  
Sbjct  509   YSMKQAIEEGFILDVIANYTTYKSYYEIEKSIQDNPEFDSKKAQKRLRAYVEASQETIDT  568

Query  552   KAEIMVDHFHAQVMGHRKVGGQARVMVITSGIMRAIEYFYAINDYLLNKKLPYKTIVAFS  611
             KAEIM++HF  +V+  +K+ G+++ MV+T  I  AI Y+ A+   L +   P+K  +AFS
Sbjct  569   KAEIMLEHFIKHVVNGKKLKGKGKGMVVTQNIESAIRYYRALTIQLNKMGNPFKVAIAFS  628

Query  612   GEHEYGGQKVTEASLNGFPSNK-----------------IEDKITEDPYRILVVADKFLT  654
             G  E +G   TEA +NGFP                    I   + +D+YR+LVVA+K+LT
Sbjct  629   GSKEVDGIEYTEADINGFPEGDTKDYFDVNYKRKEPDSPIPKHVDQDAYRLLVVANKYLT  688

Query  655   GYDEPLMHTMYVDKPLAGIKAVQTLSRLNRAHP----KKHDTFILDFFNDADVIQKAFSD  710
             G+D+P + +MYVDK LA++  VQ+LSRLNR+ P    K +D F+LDFFN  D I+ AF  
Sbjct  689   GFDQPKLCAMYVDKKLASVLCVQALSRLNRSAPKYGKKTEDLFVLDFFNSVDDIKTAFDP  748

Query  711   YYRTTILSEETDPNKLHDLKSDLDSYQVYSQEQIDRLVELYLGGAERETLDPVLDACVAV  770
             +Y +T LSE TD N LH+LK D+D   VY   +++ +   ++ G E + L P++D   A 
Sbjct  749   FYTSTTLSEATDVNVLHELKDDMDDTGVYEWFEVEEFNKRFFEGREAQDLSPIIDIAAAR  808

Query  771   YNSELDEDGQ--VDFKGKAKAFVRTYGFLASILPFTNPDWEKLSIFLNFLISKLPA--PK  826
             +N EL+ + +  VDFK KAK FV+ YG +ASI+P+   +WEKL  FL+FLI+KL+   P 
Sbjct  809   FNHELELENEFKVDFKVKAKQFVKIYGQIASIMPYEVVQWEKLFWFLKFLIPKLSVEDPD  868

Query  827   EEDLSKGILETIDMDSYRAE-VQASMNITLADGDAELDA-VPTTGGGRKPEPELDQLSNI  884
              E L  ++L+++D+ SY  + V+ + +I L D+++ELD+  P   G+  PE+E D L +I
Sbjct  869   KEALD-SLLDSVDLSSYGLQRVKLNHSIELDDSETELDPQNPNPRGAYGPEAEKDPLDEI  927

Query  885   IKTFND-LFGNIDWKDADKIRKVIAEEIPDKVAADSAYQNAMKNSDKQNAR-IEHDKALG  942
             IK FN+  F    W  +   ++V   +I++ +  ++ ++   +N+   ++R +  +K L 
Sbjct  928   IKIFNERWFQG--WSATPEEQRVKFVNIAESIRNHPDFEAKYQNNADPHTRELAFEKMLK  985

Query  943   RVMVELIADHTELFKQFSDNPSFK-KW  968
              +M++   D+ EL+K F+++P+FK  W
Sbjct  986   EIMLQRRKDELELYKLFAQDPAFKASW  1012

64) join in NC_020288


> EU272902|14|G13|167832520|ACA01830.1|Vibrio_cholerae_Amazonia_3509|-|13968..17036|-|VPI2_0013c|type 
I restriction enzyme 
HsdR
Length=1022

 Score =  588 bits (2220),  Expect = 5e-169, Method: Compositional matrix adjust.
 Identities = 422/1019 (42%), Positives = 658/1019 (65%), Gaps = 72/1019 (7%)

Query  5     DTSEKGLETIIVNSLV--------NEAGYVLGDPKDYDREHAVDLVKLLEFLETTQPDTY  56
              + EKGL  I  + L         N+  Y++G P D+D++ A+D   + +FLE TQ+   
Sbjct  15    AAIEKGLAGICKEELALGEAPLNYNNDLYLIGSPSDFDKQYALDTRLFWQFLEDTQASEL  74

Query  57    GVLGINREGPKRTQFLHRLQGEIAKRGVVDALQTGIRHGPAHVELFYGTPTPGNVKAVER  116
               L        + ++L+R++  I ++GV+  L+ G+  + A + L Y +P +++   V +
Sbjct  75    EKLKRTSPHDWQRKILERFDRMIMRHGVLRLLKKGLDVDDAFLSLMYPAPLASSSEKVKK  134

Query  117   -FSNNIFSVTRQLRYSSVETALSLDMAVFINGLPIATFELKNRLTKQ-TVLDAVEQYQRD  174
              FS N+FSVTRQ+ YS+ +    +DM +FING+P+ T+ELKN  T Q +V ++  QY+ D
Sbjct  135   DFSANLFSVTRQVCYSNANPLEEIDMVLFINGIPLITLELKNPWTGQNAVYHGQKQYRDD  194

Query  175   RDPKELLLQFGRCAVHFAVDDHEVRFCTHLTGKGSWFLPFNKGHNDgagnppnpngIATD  234
             RD+++ LL+F+RC VH AVD +EV   T L+GK + FLPFNKG N G GNP NP+G  T 
Sbjct  195   RDANQPLLNFARCLVHMAVDTDEVYMTTKLAGKNTFFLPFNKGFNFGKGNPINPHGHKTA  254

Query  235   YLWKEVLTKEGLTDILENYAQIVEEKDEKTCRKKLKQVFPRYHQLTVVRQLLATAKQDGV  294
             YLW+EV+ KE++++I++++ ++      +  ++ L   FPRYHQ+ VVR+L+     +GV
Sbjct  255   YLWQEVFRKESIANIIQHFIRLDGSSKKQLDKRTL--FFPRYHQMDVVRRLVDHCSVNGV  312

Query  295   GKRYLIQHSAGSGKSNSIAWLAHQLVG---LEQD-----GK--ALFDSIIVVTDRQVLDR  344
             G+ YLIQHSAGSGKSNSI+W A QL+    + +D     GK  +LFDS+IVVTDR++LD+
Sbjct  313   GQTYLIQHSAGSGKSNSITWAAYQLIETYPISDDLPGSRGKEVPLFDSVIVVTDRRLLDK  372

Query  345   QIRNTIKQFAQVSATVGHAERSGDLRQFIKDGKKVIITTVQKFPFILNEIGDEHRQSKFA  404
             Q+R+ IK+F++V   V+ A +S++L+  + +GKK+IITT+QKFP+I++ I+D   + +FA
Sbjct  373   QLRDNIKEFSEVKNIVAPAFKSSELKSALENGKKIIITTIQKFPYIVDGIAD-LSDRRFA  431

Query  405   IVIDEAHSSQGGKTTAAMNRVLEGTASYNVANeeeeetteDKINRILEGRKMVTNASYFA  464
             ++IDEAHSSQ+G         L+ + ++   +        DK  +    RKM +NASYFA
Sbjct  432   VIIDEAHSSQDGHNQDK----LNEAMGFVSEDVL------DKALQSAKNRKMRSNASYFA  481

Query  465   FTATPKNKTLEIFGQPAPQPDGTVKHY-PFHSYTMKQAIQEGFILDVLKSYTPVESYYRL  523
             FTATPKN TLE FGQ   Q+DGT   Y PFH Y+MKQAI+EGFILDV+ +YT   SYY +
Sbjct  482   FTATPKNTTLEKFGQR--QADGT---YVPFHLYSMKQAIEEGFILDVIANYTTYKSYYEI  536

Query  524   AKTVEDDPLFDAKKAQKKLRRYVESHQHAIREKTEIMVDHFHTQVINHGKIGGQARAMVI  583
              K+++D+P FD+KKAQK+LR YVE+ Q++I  K+EIM++HF  +V+N  K+ G++++MV+
Sbjct  537   EKSIQDNPEFDSKKAQKRLRAYVEASQETIDTKAEIMLEHFIKHVVNGKKLKGKGKGMVV  596

Query  584   TNGIGQAIQYFYAFKDYLRERKSPYQAIVAFSGEYDYGGQKVTEATLNGF----------  633
             T+ I  AI+Y+ A+   L    +P++  +AFSG  + +G   TEA +NGF          
Sbjct  597   TQNIESAIRYYRALTIQLNKMGNPFKVAIAFSGSKEVDGIEYTEADINGFPEGDTKDYFD  656

Query  634   -------PSSQITDKIEEDPYRFLIVADKYQTGYDQPLLHTMYVDKALSGIKAVQTLSRL  686
                    P S I   +++D+YR+L+VA+KY TG+DQP L +MYVDK L+++  VQ+LSRL
Sbjct  657   VNYKRKEPDSPIPKHVDQDAYRLLVVANKYLTGFDQPKLCAMYVDKKLASVLCVQALSRL  716

Query  687   NRAHPQKY-----DTFVLDFYNDSGTIQSSFDPYYRTTILSNETDPNKLHDLKADLDSHQ  741
             NR+ P KY     D FVLDF+N  + I+++FDP+Y +T LS+ TD N LH+LK D+D   
Sbjct  717   NRSAP-KYGKKTEDLFVLDFFNSVDDIKTAFDPFYTSTTLSEATDVNVLHELKDDMDDTG  775

Query  742   VYTQEQIQYLVELYLNGADRDRLDPVLDACVAAYNADLDEDGQ--VDFKGKAKAFVRTYG  799
             VY   +++ +   +++G + + L P++D   A +N +L+ + +  VDFK KAK FV+ YG
Sbjct  776   VYEWFEVEEFNKRFFEGREAQDLSPIIDIAAARFNHELELENEFKVDFKVKAKQFVKIYG  835

Query  800   FLASILPYSNADWEKLSIFLNFLIPKLPA--PKEEDLSRGILEAIDMDSYRVE-LKTSLK  856
              +ASI+PY   +WEKL  FL+FLIPKL+   P  E L  ++L+++D+ SY ++ +K +  
Sbjct  836   QIASIMPYEVVQWEKLFWFLKFLIPKLSVEDPDKEALD-SLLDSVDLSSYGLQRVKLNHS  894

Query  857   IDLADEDAEIKP-VPTAGGGSKPEADLDQLSNIIKAFNDQFGNINWKDNDKIRRVIAEEI  915
             I+L D ++E+ P  P + G+  PEA+ D L +IIK FN++  +  W      +RV   +I
Sbjct  895   IELDDSETELDPQNPNPRGAYGPEAEKDPLDEIIKIFNERWFQ-GWSATPEEQRVKFVNI  953

Query  916   PAKVAADVAYQNAMRNNDKRTAR-IEHDAALQRVMIELLADHTELFKQFSDNQSFK-KW  972
             +  +  +  ++   +NN    +R +  +  L+ +M++   D+ EL+K F+++ +FK  W
Sbjct  954   AESIRNHPDFEAKYQNNADPHTRELAFEKMLKEIMLQRRKDELELYKLFAQDPAFKASW  1012

65) join in NC_005231


> EU272902|14|G13|167832520|ACA01830.1|Vibrio_cholerae_Amazonia_3509|-|13968..17036|-|VPI2_0013c|type 
I restriction enzyme 
HsdR
Length=1022

 Score =  588 bits (2220),  Expect = 5e-169, Method: Compositional matrix adjust.
 Identities = 422/1019 (42%), Positives = 658/1019 (65%), Gaps = 72/1019 (7%)

Query  5     DTSEKGLETIIVNSLV--------NEAGYVLGDPKDYDREHAVDLVKLLEFLETTQPDTY  56
              + EKGL  I  + L         N+  Y++G P D+D++ A+D   + +FLE TQ+   
Sbjct  15    AAIEKGLAGICKEELALGEAPLNYNNDLYLIGSPSDFDKQYALDTRLFWQFLEDTQASEL  74

Query  57    GVLGINREGPKRTQFLHRLQGEIAKRGVVDALQTGIRHGPAHVELFYGTPTPGNVKAVER  116
               L        + ++L+R++  I ++GV+  L+ G+  + A + L Y +P +++   V +
Sbjct  75    EKLKRTSPHDWQRKILERFDRMIMRHGVLRLLKKGLDVDDAFLSLMYPAPLASSSEKVKK  134

Query  117   -FSNNIFSVTRQLRYSSVETALSLDMAVFINGLPIATFELKNRLTKQ-TVLDAVEQYQRD  174
              FS N+FSVTRQ+ YS+ +    +DM +FING+P+ T+ELKN  T Q +V ++  QY+ D
Sbjct  135   DFSANLFSVTRQVCYSNANPLEEIDMVLFINGIPLITLELKNPWTGQNAVYHGQKQYRDD  194

Query  175   RDPKELLLQFGRCAVHFAVDDHEVRFCTHLTGKGSWFLPFNKGHNDgagnppnpngIATD  234
             RD+++ LL+F+RC VH AVD +EV   T L+GK + FLPFNKG N G GNP NP+G  T 
Sbjct  195   RDANQPLLNFARCLVHMAVDTDEVYMTTKLAGKNTFFLPFNKGFNFGKGNPINPHGHKTA  254

Query  235   YLWKEVLTKEGLTDILENYAQIVEEKDEKTCRKKLKQVFPRYHQLTVVRQLLATAKQDGV  294
             YLW+EV+ KE++++I++++ ++      +  ++ L   FPRYHQ+ VVR+L+     +GV
Sbjct  255   YLWQEVFRKESIANIIQHFIRLDGSSKKQLDKRTL--FFPRYHQMDVVRRLVDHCSVNGV  312

Query  295   GKRYLIQHSAGSGKSNSIAWLAHQLVG---LEQD-----GK--ALFDSIIVVTDRQVLDR  344
             G+ YLIQHSAGSGKSNSI+W A QL+    + +D     GK  +LFDS+IVVTDR++LD+
Sbjct  313   GQTYLIQHSAGSGKSNSITWAAYQLIETYPISDDLPGSRGKEVPLFDSVIVVTDRRLLDK  372

Query  345   QIRNTIKQFAQVSATVGHAERSGDLRQFIKDGKKVIITTVQKFPFILNEIGDEHRQSKFA  404
             Q+R+ IK+F++V   V+ A +S++L+  + +GKK+IITT+QKFP+I++ I+D   + +FA
Sbjct  373   QLRDNIKEFSEVKNIVAPAFKSSELKSALENGKKIIITTIQKFPYIVDGIAD-LSDRRFA  431

Query  405   IVIDEAHSSQGGKTTAAMNRVLEGTASYNVANeeeeetteDKINRILEGRKMVTNASYFA  464
             ++IDEAHSSQ+G         L+ + ++   +        DK  +    RKM +NASYFA
Sbjct  432   VIIDEAHSSQDGHNQDK----LNEAMGFVSEDVL------DKALQSAKNRKMRSNASYFA  481

Query  465   FTATPKNKTLEIFGQPAPQPDGTVKHY-PFHSYTMKQAIQEGFILDVLKSYTPVESYYRL  523
             FTATPKN TLE FGQ   Q+DGT   Y PFH Y+MKQAI+EGFILDV+ +YT   SYY +
Sbjct  482   FTATPKNTTLEKFGQR--QADGT---YVPFHLYSMKQAIEEGFILDVIANYTTYKSYYEI  536

Query  524   AKTVEDDPLFDAKKAQKKLRRYVESHQHAIREKTEIMVDHFHTQVINHGKIGGQARAMVI  583
              K+++D+P FD+KKAQK+LR YVE+ Q++I  K+EIM++HF  +V+N  K+ G++++MV+
Sbjct  537   EKSIQDNPEFDSKKAQKRLRAYVEASQETIDTKAEIMLEHFIKHVVNGKKLKGKGKGMVV  596

Query  584   TNGIGQAIQYFYAFKDYLRERKSPYQAIVAFSGEYDYGGQKVTEATLNGF----------  633
             T+ I  AI+Y+ A+   L    +P++  +AFSG  + +G   TEA +NGF          
Sbjct  597   TQNIESAIRYYRALTIQLNKMGNPFKVAIAFSGSKEVDGIEYTEADINGFPEGDTKDYFD  656

Query  634   -------PSSQITDKIEEDPYRFLIVADKYQTGYDQPLLHTMYVDKALSGIKAVQTLSRL  686
                    P S I   +++D+YR+L+VA+KY TG+DQP L +MYVDK L+++  VQ+LSRL
Sbjct  657   VNYKRKEPDSPIPKHVDQDAYRLLVVANKYLTGFDQPKLCAMYVDKKLASVLCVQALSRL  716

Query  687   NRAHPQKY-----DTFVLDFYNDSGTIQSSFDPYYRTTILSNETDPNKLHDLKADLDSHQ  741
             NR+ P KY     D FVLDF+N  + I+++FDP+Y +T LS+ TD N LH+LK D+D   
Sbjct  717   NRSAP-KYGKKTEDLFVLDFFNSVDDIKTAFDPFYTSTTLSEATDVNVLHELKDDMDDTG  775

Query  742   VYTQEQIQYLVELYLNGADRDRLDPVLDACVAAYNADLDEDGQ--VDFKGKAKAFVRTYG  799
             VY   +++ +   +++G + + L P++D   A +N +L+ + +  VDFK KAK FV+ YG
Sbjct  776   VYEWFEVEEFNKRFFEGREAQDLSPIIDIAAARFNHELELENEFKVDFKVKAKQFVKIYG  835

Query  800   FLASILPYSNADWEKLSIFLNFLIPKLPA--PKEEDLSRGILEAIDMDSYRVE-LKTSLK  856
              +ASI+PY   +WEKL  FL+FLIPKL+   P  E L  ++L+++D+ SY ++ +K +  
Sbjct  836   QIASIMPYEVVQWEKLFWFLKFLIPKLSVEDPDKEALD-SLLDSVDLSSYGLQRVKLNHS  894

Query  857   IDLADEDAEIKP-VPTAGGGSKPEADLDQLSNIIKAFNDQFGNINWKDNDKIRRVIAEEI  915
             I+L D ++E+ P  P + G+  PEA+ D L +IIK FN++  +  W      +RV   +I
Sbjct  895   IELDDSETELDPQNPNPRGAYGPEAEKDPLDEIIKIFNERWFQ-GWSATPEEQRVKFVNI  953

Query  916   PAKVAADVAYQNAMRNNDKRTAR-IEHDAALQRVMIELLADHTELFKQFSDNQSFK-KW  972
             +  +  +  ++   +NN    +R +  +  L+ +M++   D+ EL+K F+++ +FK  W
Sbjct  954   AESIRNHPDFEAKYQNNADPHTRELAFEKMLKEIMLQRRKDELELYKLFAQDPAFKASW  1012

66) Glov_2197 in NC_010814


> EU272902|14|G13|167832520|ACA01830.1|Vibrio_cholerae_Amazonia_3509|-|13968..17036|-|VPI2_0013c|type 
I restriction enzyme 
HsdR
Length=1022

 Score =  587 bits (2216),  Expect = 1e-168, Method: Compositional matrix adjust.
 Identities = 422/1021 (42%), Positives = 655/1021 (65%), Gaps = 57/1021 (5%)

Query  1     MTTDTSERGLEDLICTTMTGRTAVVAAGGVHDPVEPFGGTGWLLGDARDYDREYCVDVTQ  60
             M + T+E++LE  I   ++G        ++ ++   +     L+G + D+D++Y +D   
Sbjct  4     MVSKTNEQALEAAIEKGLAG--ICKEELALGEAPLNYNNDLYLIGSPSDFDKQYALDTRL  61

Query  61    LHAFVEATQPEIATALE-LEKDTPV--RRRFLARVESECARRGVIDLLRKGVKHEKYHID  117
             +  F+E TQ   A+ LE L + +P   +R++L R +    R+GV+ LL+KG+  +   + 
Sbjct  62    FWQFLEDTQ---ASELEKLKRTSPHDWQRKILERFDRMIMRHGVLRLLKKGLDVDDAFLS  118

Query  118   LFYGSP-SPGNDKAAQLYIANRFSLTRQLRYSRDETRRALDLALFINGLPIATFELKNSL  176
             L Y +P +++++K  + + AN FS+TRQ+ YS  +    +D+ LFING+P+ T+ELKN+ 
Sbjct  119   LMYPAPLASSSEKVKKDFSANLFSVTRQVCYSNANPLEEIDMVLFINGIPLITLELKNPW  178

Query  177   TKQ-TVEDAIEQYRRDRDPRERLFSFGRCIVHFAVDDREVQMCTELKGKGSWFLPFNLGW  235
             T Q +V ++  QYR DRD+ + L++F+RC+VH AVD  EV M T L GK + FLPFN G 
Sbjct  179   TGQNAVYHGQKQYRDDRDANQPLLNFARCLVHMAVDTDEVYMTTKLAGKNTFFLPFNKGF  238

Query  236   NDGAGNPPNPHGLKTDYLWKRVLTLQGVTDIIENYAQIVEEINPKTRKKSRKQVFPRYHQ  295
             N G GNP NPHG KT YLW+ V+  +++++II+++ ++  + ++K +   R   FPRYHQ
Sbjct  239   NFGKGNPINPHGHKTAYLWQEVFRKESIANIIQHFIRL--DGSSKKQLDKRTLFFPRYHQ  296

Query  296   LDVVRRLLADALKQGVGQRYLIQHSAGSGKSNSIAWLAHQLV---ALRKD-----GKD--  345
             +DVVRRL+ +   +GVGQ YLIQHSAGSGKSNSI+W A QL+   ++  D     GK+  
Sbjct  297   MDVVRRLVDHCSVNGVGQTYLIQHSAGSGKSNSITWAAYQLIETYPISDDLPGSRGKEVP  356

Query  346   LFDSIIVITDRRILDDQIKNTIKGFMQVGSTVGHAEHSGDLRKFIESGKKIIISTVQKFP  405
             LFDS+IV+TDRR+LD Q+++ IK F +V + V+ A  S++L+  +E+GKKIII+T+QKFP
Sbjct  357   LFDSVIVVTDRRLLDKQLRDNIKEFSEVKNIVAPAFKSSELKSALENGKKIIITTIQKFP  416

Query  406   YILNEIGDEHRGRSFAIIIDEAHSSQggkaagalnaalTDPEDEINDVLEKRMAARKMLT  465
             YI++ I+D   +R FA+IIDEAHSSQ+G   + LN A+    +++ D   +    RKM +
Sbjct  417   YIVDGIAD-LSDRRFAVIIDEAHSSQDGHNQDKLNEAMGFVSEDVLDKALQSAKNRKMRS  475

Query  466   NASYFAFTATPKNKTLEIFGEPYPGEEGKVKHRPFHCYTMKQAIQEGFILDVLKSYTPVN  525
             NASYFAFTATPKN TLE FG+     ++     PFH Y+MKQAI+EGFILDV+ +YT  +
Sbjct  476   NASYFAFTATPKNTTLEKFGQR----QADGTYVPFHLYSMKQAIEEGFILDVIANYTTYK  531

Query  526   SYYKLIKKVKDDPEFDKNKAQKKLRRYVESHDHAIRLKAEIMVDHFREQVIAKGKIGGQA  585
             SYY + K ++D+PEFD +KAQK+LR YVE+ +++I  KAEIM++HF  +V+   K+ G++
Sbjct  532   SYYEIEKSIQDNPEFDSKKAQKRLRAYVEASQETIDTKAEIMLEHFIKHVVNGKKLKGKG  591

Query  586   RVMVVCNGIERAIQYFHAIKSYLEEQKSPYQAIVAFSGEYDFRGQKVTEASLNGFPSGD-  644
             + MVV + IE AI+Y++A+   L+   +P++  +AFSG  +  G   TEA +NGFP GD 
Sbjct  592   KGMVVTQNIESAIRYYRALTIQLNKMGNPFKVAIAFSGSKEVDGIEYTEADINGFPEGDT  651

Query  645   ----------------IADKIQEDPYRILVCADKFQTGYDEPLLHTMYVDKTLSGIKAVQ  688
                             I+  +++D+YR+LV A+K+ TG+D+P L +MYVDK L+++  VQ
Sbjct  652   KDYFDVNYKRKEPDSPIPKHVDQDAYRLLVVANKYLTGFDQPKLCAMYVDKKLASVLCVQ  711

Query  689   TLSRLNRAHP----RKHDVFVLDFMNDADTIQAAFADYYRTTVLSEETDPNKLHDLKAVL  744
             +LSRLNR+ P    + +D+FVLDF N  D I++AF  +Y +T LSE TD N LH+LK  +
Sbjct  712   ALSRLNRSAPKYGKKTEDLFVLDFFNSVDDIKTAFDPFYTSTTLSEATDVNVLHELKDDM  771

Query  745   DNYHVYRAAVVDELVGLYLGGAQRDKLDPLLDACVAVYIEELHEDAQ--IDFKGKAKAFT  802
             D+  VY    V+E+   ++ G + + L P++D   A + +EL+ + +  +DFK KAK F 
Sbjct  772   DDTGVYEWFEVEEFNKRFFEGREAQDLSPIIDIAAARFNHELELENEFKVDFKVKAKQFV  831

Query  803   RTYEFLSSILPYSDVDWEKLSIFLSFLIPKLPA--PQEEDLSKGILESIDMDSYRTEKQA  860
             + Y  ++SI+PY  V+WEKL  FL FLIPKL+   P+ E L  ++L+S+D+ SY  ++  
Sbjct  832   KIYGQIASIMPYEVVQWEKLFWFLKFLIPKLSVEDPDKEALD-SLLDSVDLSSYGLQRVK  890

Query  861   VMNII-LADEEAEIDP-IPVGGGGGKPQPDMDKLTNILKSFNEQFGTLFSDVDRVAKRIQ  918
             + + I L D E+E+DP  P   G+  P+++ D L +I+K FNE+     S      +   
Sbjct  891   LNHSIELDDSETELDPQNPNPRGAYGPEAEKDPLDEIIKIFNERWFQGWSATPEEQRVKF  950

Query  919   DDVAPKVAADQAY--RNAKQNTPNAARLEHDKALARVMLSLLKDDTEAYKQFVENESFKR  976
              ++A  +  +  +  +  ++  P++  L  +K L  +ML   KD+ E YK F ++ +FK 
Sbjct  951   VNIAESIRNHPDFEAKYQNNADPHTRELAFEKMLKEIMLQRRKDELELYKLFAQDPAFKA  1010

Query  977   S  977
             S
Sbjct  1011  S  1011

67) Tery_4471 in NC_008312


> EU272902|14|G13|167832520|ACA01830.1|Vibrio_cholerae_Amazonia_3509|-|13968..17036|-|VPI2_0013c|type 
I restriction enzyme 
HsdR
Length=1022

 Score =  586 bits (2215),  Expect = 1e-168, Method: Compositional matrix adjust.
 Identities = 424/1035 (41%), Positives = 665/1035 (65%), Gaps = 86/1035 (8%)

Query  1     MASDITEKGLENIIYQSLIDDCQ----------------YLEGNPKDYDQTYCIDTEKLF  44
             M S   E++LE  I ++L + C+                YL G+P D+D+ Y +DT  + 
Sbjct  4     MVSKTNEQALEAAIEKGLAGICKEELALGEAPLNYNNDLYLIGSPSDFDKQYALDTRLFW  63

Query  45    QFLQNTQPEKLTEISNYHGANWEKKLYERLHHQIEEKSIVNILRQGIKTGETHLELYYKL  104
             QFL++TQ+  L  +      +W++K+ ER+++ I   +++ +L++G+  +++ L L Y  
Sbjct  64    QFLEDTQASELEKLKRTSPHDWQRKILERFDRMIMRHGVLRLLKKGLDVDDAFLSLMYPA  123

Query  105   PTSQLNPDTIENFQENVFSVTRQLKYKENRNFS-LDLVIFINGLPVITFELKNQLTKQN-  162
             P +  +     +F  N+FSVTRQ+ Y +   +  +D+V+FING+P+IT+ELKN  T QN 
Sbjct  124   PLASSSEKVKKDFSANLFSVTRQVCYSNANPLEEIDMVLFINGIPLITLELKNPWTGQNA  183

Query  163   -FRDAINQYKNDRRPRELLFQFKRCLVHFALDADEVWMTTKLNGKNTEFIPFNKGKKSNP  221
              +++  +QY++DR + + L++F RCLVH A+D+DEV MTTKL GKNT F+PFNKG     
Sbjct  184   VYHGQ-KQYRDDRDANQPLLNFARCLVHMAVDTDEVYMTTKLAGKNTFFLPFNKG-----  237

Query  222   DLPFPDTAGNPPNPNHIKTDYLWKEILTIESLGNIIEHYAQliekeedkdkdkktvkklk  281
                F    GNP NP+  KT YLW+E++  ES++NII+H+ +L      +   +       
Sbjct  238   ---FNFGKGNPINPHGHKTAYLWQEVFRKESIANIIQHFIRLDGSSKKQLDKRTL-----  289

Query  282   lIFPRYHQLDLVKQLLTSAKKHGVGNRYLIQHSAGSGKSNSITWLSHQLVE-------LK  334
              +FPRYHQ+D+V++L+     +GVG+ YLIQHSAGSGKSNSITW + QL+E       L 
Sbjct  290   -FFPRYHQMDVVRRLVDHCSVNGVGQTYLIQHSAGSGKSNSITWAAYQLIETYPISDDLP  348

Query  335   NITEKE-NIFDSVLVVTDRKILDKQIRENIQQFAQEDKVVEATKNSKKLKSALENKRKII  393
                 KE  +FDSV+VVTDR++LDKQ+R+NI++F++  ++V ++ +S  LKSALEN +KII
Sbjct  349   GSRGKEVPLFDSVIVVTDRRLLDKQLRDNIKEFSEVKNIVAPAFKSSELKSALENGKKII  408

Query  394   ITTVQKFPYVVKEIQSLSDHKFAIIIDEAHSSQTGKSAASMSESLSKKDSEVEETTEDKI  453
             ITT+QKFPY+V  I  LSD++FA+IIDEAHSSQ G +   ++E+++     V E   DK 
Sbjct  409   ITTIQKFPYIVDGIADLSDRRFAVIIDEAHSSQDGHNQDKLNEAMGF----VSEDVLDKA  464

Query  454   IRIIESQKLCPNANYYAFTATPKNKTLELFGVKNPEDGKFYPFHSYSMKQAIEEGFILNV  513
             ++   ++K+ +NA+Y+AFTATPKN TLE FG +++ DG + PFH YSMKQAIEEGFIL+V
Sbjct  465   LQSAKNRKMRSNASYFAFTATPKNTTLEKFGQRQA-DGTYVPFHLYSMKQAIEEGFILDV  523

Query  514   LQHYTTYKTYCRLEKKVIDDPEFDSKQAKKKLKQYVEEDQESIRKKSEVMIEHFLSKVIA  573
             + +YTTYK+Y  +EK + D+PEFDSK+A+K+L+ YVE  QE+I  K+E+M+EHF+  V+ 
Sbjct  524   IANYTTYKSYYEIEKSIQDNPEFDSKKAQKRLRAYVEASQETIDTKAEIMLEHFIKHVVN  583

Query  574   QGKINGKAKAMVVSNSIKSAIYYKKAFDKYLREKKSDYQTIVAFSGSKEIDGKKENESSM  633
               K++GK+K+MVV+++I SAI Y +A+   L    + ++  +AFSGSKE+DG    E+ +
Sbjct  584   GKKLKGKGKGMVVTQNIESAIRYYRALTIQLNKMGNPFKVAIAFSGSKEVDGIEYTEADI  643

Query  634   NGFSSSKITEKF-----------------NDSKYRFLIVANKYQTGFDEPLLHTMYVDKV  676
             NGF+ +   + F                 ++  YR+L+VANKY TGFD+P L +MYVDK 
Sbjct  644   NGFPEGDTKDYFDVNYKRKEPDSPIPKHVDQDAYRLLVVANKYLTGFDQPKLCAMYVDKK  703

Query  677   LSDVKAVQTLSRLNRSCE--GKT--DTFVLDFVNSADEIQRAFEPYYKTTILSEETDSDR  732
             L+ V  VQ+LSRLNRS    GK   D FVLDF NS D+I+ AF+P+Y +T LSE TD + 
Sbjct  704   LASVLCVQALSRLNRSAPKYGKKTEDLFVLDFFNSVDDIKTAFDPFYTSTTLSEATDVNV  763

Query  733   LYDLEDSLASFQIYSQENVEKFMKLFLNCESRENWESILDICVEKYNCDL-LEEE-KIEF  790
             L +L D +    +Y   +VE F K F++    ++  +I+DI   ++N +L LE+E K++F
Sbjct  764   LHELKDDMDDTGVYEWFEVEEFNKRFFEGREAQDLSPIIDIAAARFNHELELENEFKVDF  823

Query  791   KSKARSFVKNYQFLVQVKSFKNSNWESLNSFLKLLVNKLPQLDNSDLSA--GIINSVDIE  848
             K KA+ FVK Y  +  + ++   +WE L  FLK+L+ KL+ ++++D  A  ++++SVD+ 
Sbjct  824   KVKAKQFVKIYGQIASIMPYEVVQWEKLFWFLKFLIPKLS-VEDPDKEALDSLLDSVDLS  882

Query  849   SY---RVELLASQSINL-SGENTLSPIAKNIVSG-NSQSRSDKVSQIIEEFNNR-FGGNI  902
             SY   RV L  ++SI+L  +E  L P   N  ++  +++  D + +II  FN+R F G  
Sbjct  883   SYGLQRVKL--NHSIELDDSETELDPQNPNPRGAYGPEAEKDPLDEIIKIFNERWFQG--  938

Query  903   VWQNEGRAWKFLLEELPEKVRGNGEYKNAI-NYSDPQNAKLTFENKFNQELRRSTREHIE  961
              W       +  + +++E +R + ++     N +DP+   L+FE+ +++ + +  ++++E
Sbjct  939   -WSATPEEQRVKFVNIAESIRNHPDFEAKYQNNADPHTRELAFEKMLKEIMLQRRKDELE  997

Query  962   EYRQFTGNKSFRE-W  975
              Y+ F+ + +F+  W
Sbjct  998   LYKLFAQDPAFKASW  1012

68) Ilyop_1053 in NC_014632


> EU272902|14|G13|167832520|ACA01830.1|Vibrio_cholerae_Amazonia_3509|-|13968..17036|-|VPI2_0013c|type 
I restriction enzyme 
HsdR
Length=1022

 Score =  581 bits (2195),  Expect = 5e-167, Method: Compositional matrix adjust.
 Identities = 407/1014 (41%), Positives = 660/1014 (66%), Gaps = 91/1014 (8%)

Query  26    YIETHSNDFDRDFCLNKKDLFEFIEISQPDSYDFIIKKGEDAF----LNRLDLKIKKEGI  81
             Y+   ++DFD+++ L+ + + +F+E +Q+   + + + + +      L+R+D  I ++G+
Sbjct  43    YLIGSPSDFDKQYALDTRLFWQFLEDTQASELEKLKRTSPHDWQRKILERFDRMIMRHGV  102

Query  82    IEVLRKGVKHFDKTIYLFYPQPNSNHNKKDHLRYETNIFSVTQELVYTGNNK-NRIDLVI  140
             + +L+KG+   D  + L YP P ++ + K    + +N+FSVT+++ Y+  N  + ID+V+
Sbjct  103   LRLLKKGLDVDDAFLSLMYPAPLASSSEKVKKDFSANLFSVTRQVCYSNANPLEEIDMVL  162

Query  141   FINGFPIITMELKNAFT-HQAVKNAIKQYKKDRDPNDKIFNFARCLVHFAIDTDLAYMTT  199
             FING+P+IT+ELKN+ T ++AV ++ KQY+ DRD+N+ ++NFARCLVH A+DTD  YMTT
Sbjct  163   FINGIPLITLELKNPWTGQNAVYHGQKQYRDDRDANQPLLNFARCLVHMAVDTDEVYMTT  222

Query  200   KLDKSKTFFMPFNKGLNNGEPFPPYGAGNPINPLGLKTSYIWRDILTRSSLSNIIEKFVH  259
             KL   +TFF+PFNKG+N       +G GNPINP G KT+Y+W++++ + S++NII+ F++
Sbjct  223   KLAGKNTFFLPFNKGFN-------FGKGNPINPHGHKTAYLWQEVFRKESIANIIQHFIR  275

Query  260   LEKPKVKS-DKSKLIFPRYHQLKVVRKLLEDSKEKGIGIKYLVQHSAGSGKSNSITWLAH  318
             L+ +  K  DK  L+FPRYHQ+ VVR+L+++   +G+G  YL+QHSAGSGKSNSITW A 
Sbjct  276   LDGSSKKQLDKRTLFFPRYHQMDVVRRLVDHCSVNGVGQTYLIQHSAGSGKSNSITWAAY  335

Query  319   QLIGLY--------DKNNISPIFDSVVVVTDKTILDKQIRENIKNFAQVKNIVEAITGNS  370
             QLI  Y         + +  P+FDSV+VVTD+ +LDKQ+R+NIK+F++VKNIV       
Sbjct  336   QLIETYPISDDLPGSRGKEVPLFDSVIVVTDRRLLDKQLRDNIKEFSEVKNIV-------  388

Query  371   TDIKKLDPTETSMSKTSHMRLALENNKKIIICTVQTFPYVLKTVQEMETKNIAFIIDEAH  430
                       ++  K+S+++ ALEN KKIII T+Q FPY++  + ++  + +A IIDEAH
Sbjct  389   ----------APAFKSSELKSALENGKKIIITTIQKFPYIVDGIADLSDRRFAVIIDEAH  438

Query  431   SGQNGISSASMNAIFSNTDFTKLKMDEEGNIDTEDLVNYL--IKTKKMLDNASYFAFTAT  488
             S+Q+G +   +N             +  G +  + L + L   K +KM  NASYFAFTAT
Sbjct  439   SSQDGHNQDKLN-------------EAMGFVSEDVLDKALQSAKNRKMRSNASYFAFTAT  485

Query  489   PKNKTLETFGTKQEDGTFKPFHNYSMKQAIEEEYILDVLQNYTTYKSYYKIKADNNVPEE  548
             PKN TLE FG +Q DGT+ PFH YSMKQAIEE +ILDV+ NYTTYKSYY I  ++++ ++
Sbjct  486   PKNTTLEKFGQRQADGTYVPFHLYSMKQAIEEGFILDVIANYTTYKSYYEI--EKSIQDN  543

Query  549   KEYEIKQANKKIKNFVEGNELAIAEKAKIMVDHFNKNVKH--LINYQAKSMVVTKSIESA  606
              E++ K+A+K+++ +VE+++ +I  KA IM++HF K+V +   ++ ++K+MVVT++IESA
Sbjct  544   PEFDSKKAQKRLRAYVEASQETIDTKAEIMLEHFIKHVVNGKKLKGKGKGMVVTQNIESA  603

Query  607   MKYKDAFDKYLKETGLPYKAIVAFSGKKAHYKTGLEMTESDMNNFSDG------------  654
             ++Y  A+   L+  G P+K  +AFSG K     G+E TE+D+N F++G            
Sbjct  604   IRYYRALTIQLNKMGNPFKVAIAFSGSKEV--DGIEYTEADINGFPEGDTKDYFDVNYKR  661

Query  655   ---DNDIVKQFRKNEYKFLIVADKFQTGFDQPLLHTMYVDKELSGVQAVQTLSRLNRA--  709
                D+ I K+  ++ Y++L+VA+K+ TGFDQP L +MYVDK L++V  VQ+LSRLNR+  
Sbjct  662   KEPDSPIPKHVDQDAYRLLVVANKYLTGFDQPKLCAMYVDKKLASVLCVQALSRLNRSAP  721

Query  710   -FKPHKTDTMVLDFYNDIESVKKAFEPYYTTTILSEETDVNKLNDLQDSLDNMQVYSEEE  768
              +     D  VLDF+N ++ +K AF+P+YT+T LSE TDVN L++L+D +D+  VY   E
Sbjct  722   KYGKKTEDLFVLDFFNSVDDIKTAFDPFYTSTTLSEATDVNVLHELKDDMDDTGVYEWFE  781

Query  769   VEEFFKLYYTNAERNILEPIINNCKEIFDTHLEKEEQIK--FKSNAKSFVRTYSYLSKII  826
             VEEF K ++   E + L PII+     F+ +LE E+++K  FK +AK FV+ Y+ ++ I+
Sbjct  782   VEEFNKRFFEGREAQDLSPIIDIAAARFNHELELENEFKVDFKVKAKQFVKIYGQIASIM  841

Query  827   EYDVPYWEKLWLFLKHLITKIKIQDEEIN--ENILNEVDMDSYRINRIG-TTKISLeeee  883
              Y+V  WEKL  FLK LI K+ ++D + +  +++L+ VD+ SY ++R+     I L++ E
Sbjct  842   PYEVVQWEKLFWFLKFLIPKLSVEDPDKEALDSLLDSVDLSSYGLQRVKLNHSIELDDSE  901

Query  884   giiepipVSTSSG-IAEKHYDTLSHIISEFN-RRFGDINWGDDVDkeeaekiliekiPDK  941
               ++P   +  ++  +E + D L +II  FN R+F    W+   +    +++ + +I++ 
Sbjct  902   TELDPQNPNPRGAYGPEAEKDPLDEIIKIFNERWFQ--GWSATPE---EQRVKFVNIAES  956

Query  942   MKANIKI-LKSIINSDKDNAKITSDEKVQDLMFDLMSTNTGIYKKFVSDPDFKN  994
             ++ +  +  K   N+D +   ++ +  ++++M++    +  +YK F  DP FK 
Sbjct  957   IRNHPDFEAKYQNNADPHTRELAFEKMLKEIMLQRRKDELELYKLFAQDPAFKA  1010

69) Ethha_1806 in NC_014828


> EU272902|14|G13|167832520|ACA01830.1|Vibrio_cholerae_Amazonia_3509|-|13968..17036|-|VPI2_0013c|type 
I restriction enzyme 
HsdR
Length=1022

 Score =  580 bits (2190),  Expect = 1e-166, Method: Compositional matrix adjust.
 Identities = 419/990 (43%), Positives = 646/990 (66%), Gaps = 61/990 (6%)

Query  25    YEQGTNDDYSKEYAVDETRLF-RFLNDTQPREMAKLGVNNSDQKKRQFLNRLSGEIAKRG  83
             Y  G+  D+ K+YA+D TRLF +FL+DTQ+ E+ KL   ++++ +R++L+R+   I ++G
Sbjct  43    YLIGSPSDFDKQYALD-TRLFWQFLEDTQASELEKLKRTSPHDWQRKILERFDRMIMRHG  101

Query  84    IIDVLRNGVKAYPADLIMFYFTP-TENNEKSKQMFEKNIFSVTRQLRYSIDASKLALDLC  142
             ++ +L++G+    A L + Y +P + ++EK K+ F  N+FSVTRQ+ YS   +   +D+ 
Sbjct  102   VLRLLKKGLDVDDAFLSLMYPAPLASSSEKVKKDFSANLFSVTRQVCYSNANPLEEIDMV  161

Query  143   LFINGLPVVTIELKNHFTGQSTA-DAVEQYKEDRDPRDTLFSFKRCMVHFAVDDQTVMFC  201
             LFING+P++T+ELKN  TGQ++  ++  QY++DRD+ + L++F RC+VH AVD + V   
Sbjct  162   LFINGIPLITLELKNPWTGQNAVYHGQKQYRDDRDANQPLLNFARCLVHMAVDTDEVYMT  221

Query  202   TKLAGKDSWFLPFNKGYNDGAGNPPNPDGIMTDYLWKDILTKWKLSRIIENYAQVVVDED  261
             TKLAGK++ FLPFNKG+N G GNP NP+G  T YLW++++ K  ++ II+++ ++     
Sbjct  222   TKLAGKNTFFLPFNKGFNFGKGNPINPHGHKTAYLWQEVFRKESIANIIQHFIRLDGSSK  281

Query  262   PDTKKKTVKQIWPRYHQLDCVEKLLTDVKQNGVGKRYLIQHSAGSGKSNSIAWLAHQLI-  320
              +  K+T+  + PRYHQ+D V +L+ +   NGVG+ YLIQHSAGSGKSNSI+W A QLI 
Sbjct  282   KQLDKRTL--FFPRYHQMDVVRRLVDHCSVNGVGQTYLIQHSAGSGKSNSITWAAYQLIE  339

Query  321   ---------GLEQDGHPMIDSVIVVTDRRILDKQIRDTIKQFMQVKNTVVWAQHSGDLKK  371
                      G      P++DSVIVVTDRR+LDKQ+RD IK+F +VKN V  A  S++LK 
Sbjct  340   TYPISDDLPGSRGKEVPLFDSVIVVTDRRLLDKQLRDNIKEFSEVKNIVAPAFKSSELKS  399

Query  372   AIQDGKRIIITTVEKFPYISQEIGQEHINNHFAIIIDEAHSGQSGRNSANMNLALSGMAS  431
             A+++GK+IIITT++KFPYI + I+ +  + +FA+IIDEAHS+Q G+N  ++N A+ G  S
Sbjct  400   ALENGKKIIITTIQKFPYIVDGIA-DLSDRRFAVIIDEAHSSQDGHNQDKLNEAM-GFVS  457

Query  432   DNEMDNEDKINAIVEGRKLVKTASYFAFTATPKNKTEEVFGTPYEEDGEIKHRPFHVYTM  491
             ++ +D   K       RK+   ASYFAFTATPKN T E FG   + +++    PFH+Y+M
Sbjct  458   EDVLD---KALQSAKNRKMRSNASYFAFTATPKNTTLEKFG---QRQADGTYVPFHLYSM  511

Query  492   KQAIQEGFILDVLKNYTAIDSWYKIAKKVEDDPMFDKKRAQKKLRSFVEGNPDVIAKKAA  551
             KQAI+EGFILDV+ NYT+  S Y I K ++D+P FD K+AQK+LR++VE++ + I  KA 
Sbjct  512   KQAIEEGFILDVIANYTTYKSYYEIEKSIQDNPEFDSKKAQKRLRAYVEASQETIDTKAE  571

Query  552   MMVDHFHEQIIAKKKLNGKSRAMVVTASIPRCIETYYAINKCLADRHSPYKAIIAFSGEC  611
             +M++HF  +++  KKL+GK+++MVVT +I   I  Y A+   L    +P+K  IAFSG  
Sbjct  572   IMLEHFIKHVVNGKKLKGKGKGMVVTQNIESAIRYYRALTIQLNKMGNPFKVAIAFSGSK  631

Query  612   KYNGQEPALTSAGLNGFPDAK-----------------IPKEFKKDPYRLLVVADMFQTG  654
               +G E   T A++NGFP++                  IPK+  +D+YRLLVVA+ + TG
Sbjct  632   EVDGIE--YTEADINGFPEGDTKDYFDVNYKRKEPDSPIPKHVDQDAYRLLVVANKYLTG  689

Query  655   FDEPLLQTMYVDKPLYDIAAVQTLSRLNRAAP--GK--DEVYVLDFANKTSTIQDAFSKF  710
             FD+P L +MYVDK L  +  VQ+LSRLNR+AP  GK  ++++VLDF N    I+ AF  F
Sbjct  690   FDQPKLCAMYVDKKLASVLCVQALSRLNRSAPKYGKKTEDLFVLDFFNSVDDIKTAFDPF  749

Query  711   YRTTILSGETDPNKLYDLITLMESYQVYDADDVEHVVDLFLGGAERDRLDPLLDPCVATY  770
             Y +T LS  TD N L +L   M+   VY+  +VE+    F+ G E + L P++D   A +
Sbjct  750   YTSTTLSEATDVNVLHELKDDMDDTGVYEWFEVEEFNKRFFEGREAQDLSPIIDIAAARF  809

Query  771   N---ELETDDQIKFKSAAKSFVRTYGFLGSILPYGNVDWEKLSIFLNLLIPKLP--SPRE  825
             N   ELE + ++ FK  AK FV+ YG ++SI+PY  V+WEKL  FL++LIPKL+   P  
Sbjct  810   NHELELENEFKVDFKVKAKQFVKIYGQIASIMPYEVVQWEKLFWFLKFLIPKLSVEDPDK  869

Query  826   DDLSEGILSTIDLDSYR-NEAQEAVAIKLEDEEAEIAP-VPAGKVGHNVEPELDPLSKII  883
             + L +++L ++DL SY  +  +   +I L+D E+E+ P  P  + +   E+E DPL  II
Sbjct  870   EAL-DSLLDSVDLSSYGLQRVKLNHSIELDDSETELDPQNPNPRGAYGPEAEKDPLDEII  928

Query  884   MDFNDM-FGNIQWNDADNVQR-QILQIPAMVSRDEKYQNAMKNSDEQEARTES-ERALQK  940
               FN+  F    W+ + + QR ++++I+  +  +  ++   +N+ + ++R  + E+ L+ 
Sbjct  929   KIFNERWFQG--WSATPEEQRVKFVNIAESIRNHPDFEAKYQNNADPHTRELAFEKMLKE  986

Query  941   VIFSIMADNMELFKQFQDNPSFK-KWLTNM  969
             +++    D++EL+K F ++P+FK  W  +M
Sbjct  987   IMLQRRKDELELYKLFAQDPAFKASWTQSM  1016

70) MCA0274 in NC_002977


> EU272902|14|G13|167832520|ACA01830.1|Vibrio_cholerae_Amazonia_3509|-|13968..17036|-|VPI2_0013c|type 
I restriction enzyme 
HsdR
Length=1022

 Score =  579 bits (2187),  Expect = 2e-166, Method: Compositional matrix adjust.
 Identities = 407/996 (41%), Positives = 638/996 (65%), Gaps = 61/996 (6%)

Query  24    YVQGHAADYNRDVALDVTQLLAFLRATQPKVVETLNLGAEGIQRTQFLHRLQGEITKRGV  83
             Y+ G ++D++++ ALD   +  FL  TQ+  +E L+  +    + ++L+R++  I ++GV
Sbjct  43    YLIGSPSDFDKQYALDTRLFWQFLEDTQASELEKLKRTSPHDWQRKILERFDRMIMRHGV  102

Query  84    VDCLRRGVSHGPVHVDL-YKLLPTPGNAAAAEAFGKNIFSVTRQVRYSNDESQRALDMVI  142
             +  L++G+  +   + L Y    ++++      F+ N+FSVTRQV YSN ++   +DMV+
Sbjct  103   LRLLKKGLDVDDAFLSLMYPAPLASSSEKVKKDFSANLFSVTRQVCYSNANPLEEIDMVL  162

Query  143   FINGLPVLTFELKNSLTKQ-TVADAIVQYQTDRNPDELLFQLGRCVAHMAVDDAEVRFCT  201
             FING+P++T+ELKN+ T Q +V ++  QY+ DR++++ L++++RC+ HMAVD  EV   T
Sbjct  163   FINGIPLITLELKNPWTGQNAVYHGQKQYRDDRDANQPLLNFARCLVHMAVDTDEVYMTT  222

Query  202   HLTGKTSWFLPFNQGWNSGAGNPPNPHGLKTDYLWKQVLVKESLANIIENYAQLVEEEAE  261
              L+GK + FLPFN+G N G GNP NPHG KT YLW++V+ KES+ANII+++ +L     +
Sbjct  223   KLAGKNTFFLPFNKGFNFGKGNPINPHGHKTAYLWQEVFRKESIANIIQHFIRL-----D  277

Query  262   DANGRKRKTRKQIFPRYHQLRTVRALLRRSQADGVGKRYLIQHSAGSGKSNTIAWLAHQL  321
             +++ ++   R  +FPRYHQ+  VR L+ +   +GVG+ YLIQHSAGSGKSN+I+W A QL
Sbjct  278   GSSKKQLDKRTLFFPRYHQMDVVRRLVDHCSVNGVGQTYLIQHSAGSGKSNSITWAAYQL  337

Query  322   VE-------LKTAADAGQAQFDSVIVITDRRALDTQIARTIRSYDHVASIYGHSESAEEL  374
             +E       L  + +   + FDSVIV+TDRR LD Q+   I+ + +V +I + +  + EL
Sbjct  338   IETYPISDDLPGSRGKEVPLFDSVIVVTDRRLLDKQLRDNIKEFSEVKNIVAPAFKSSEL  397

Query  375   RTFLRRGKKIIVTTVQKFPFILDELGDLGDKKFALLIDEAHSSQGGKTTAKMHLALSGQA  434
             ++ L  GKKII+TT+QKFP+I+D ++DL+D++FA++IDEAHSSQ+G    K++ A++   
Sbjct  398   KSALENGKKIIITTIQKFPYIVDGIADLSDRRFAVIIDEAHSSQDGHNQDKLNEAMG---  454

Query  435   AeggedeeeesvedKVNALIESRKMLANASYYAFTATPKTKTLELFGERQVVGDTVQFRS  494
                      E V DK      +RKM +NASY+AFTATPK  TLE FG+RQ  G  V F+ 
Sbjct  455   ------FVSEDVLDKALQSAKNRKMRSNASYFAFTATPKNTTLEKFGQRQADGTYVPFH-  507

Query  495   PEELTYTTKQAIQEGFILDVIANYTPVSSFYHIAKTVEHDPEVDKAKALKKIRRYVESHD  554
                  Y+ KQAI+EGFILDVIANYT   S+Y+I K+++++PE D  KA K++R YVE+ +
Sbjct  508   ----LYSMKQAIEEGFILDVIANYTTYKSYYEIEKSIQDNPEFDSKKAQKRLRAYVEASQ  563

Query  555   KAIRRKAEIMVDHFIEQVIGAKKIGGKARAMIVCNGIARAIDYFREVSDYLREIKSPYKA  614
              +I  KAEIM++HFI +V+ +KK+ GK+++M+V + I  AI Y+R ++  L  + +P+K 
Sbjct  564   ETIDTKAEIMLEHFIKHVVNGKKLKGKGKGMVVTQNIESAIRYYRALTIQLNKMGNPFKV  623

Query  615   IVAYSGDFEVGGVKKTEADLNGFPSKD-----------------IPAKLRQDPYRFLIVA  657
              +A+SG  EV+G+  TEAD+NGFP  D                 IP  + QD+YR+L+VA
Sbjct  624   AIAFSGSKEVDGIEYTEADINGFPEGDTKDYFDVNYKRKEPDSPIPKHVDQDAYRLLVVA  683

Query  658   NKFVTGFDEPLLHTMYVDKPLAGVLAVQTLSRLNRAHP----QKADTFVLDFADNAEAVK  713
             NK++TGFD+P L +MYVDK LA+VL VQ+LSRLNR+ P    +  D FVLDF ++ + +K
Sbjct  684   NKYLTGFDQPKLCAMYVDKKLASVLCVQALSRLNRSAPKYGKKTEDLFVLDFFNSVDDIK  743

Query  714   AAFQEYYRATIQEGETDPNKLHDLKSDLDAQQVYSWQQVEDLVAQYLGGAERDQLDPILD  773
             +AF+ +Y +T     TD N LH+LK D+D   VY W +VE++  +++ G E ++L PI+D
Sbjct  744   TAFDPFYTSTTLSEATDVNVLHELKDDMDDTGVYEWFEVEEFNKRFFEGREAQDLSPIID  803

Query  774   ACVAEYVEKLSEDDQ--VKFKGKAKAFVRSYGFLAAILPYGHPAWEKLSIFLNFLIPKLP  831
                A + + L  +++  V FK KAK FV+ YG +A+I+PY    WEKL  FL+FLIPKL+
Sbjct  804   IAAARFNHELELENEFKVDFKVKAKQFVKIYGQIASIMPYEVVQWEKLFWFLKFLIPKLS  863

Query  832   --APKEEDLSKGVLEAIDMDSY--raqaqasmrmamddadaFVeppppggsggsgepeLD  887
                P  E L  ++L+++D+ SY  +           D    +    P   ++ + E+E D
Sbjct  864   VEDPDKEALD-SLLDSVDLSSYGLQRVKLNHSIELDDSETELDPQNPNPRGAYGPEAEKD  922

Query  888   RLSNIIKQFND-LFGNIEWHDADKIRKVVTEEIPARVAQDKAYQNAQANSGKQNAR-LEH  945
              L +IIK FN+  F    W  +   ++V   +I+  + ++  ++    N++  ++R L  
Sbjct  923   PLDEIIKIFNERWFQG--WSATPEEQRVKFVNIAESIRNHPDFEAKYQNNADPHTRELAF  980

Query  946   DKALNRVVLELLDDHTELFKQFSDNPNFK-RWLADM  980
             +K L+ ++L+   D+ EL+K F+++P FK  W   M
Sbjct  981   EKMLKEIMLQRRKDELELYKLFAQDPAFKASWTQSM  1016

71) MELS_1617 in NC_015873


> EU272902|14|G13|167832520|ACA01830.1|Vibrio_cholerae_Amazonia_3509|-|13968..17036|-|VPI2_0013c|type 
I restriction enzyme 
HsdR
Length=1022

 Score =  579 bits (2186),  Expect = 3e-166, Method: Compositional matrix adjust.
 Identities = 411/990 (42%), Positives = 640/990 (65%), Gaps = 61/990 (6%)

Query  25    YQQGTNEDYNKEYAIDETRLF-RFLNDTQPKEMAKLGVNQSDQKKRQFLNRLSGEITRRG  83
             Y  G+  D++K+YA+D TRLF +FL+DTQ+ E+ KL    +++ +R++L+R+   I R+G
Sbjct  43    YLIGSPSDFDKQYALD-TRLFWQFLEDTQASELEKLKRTSPHDWQRKILERFDRMIMRHG  101

Query  84    IIDVLRNGIKAYPADLILFYFTP-TENNEQAKRLFDQNIFSVTRQLRYAIDASKLALDLC  142
             ++ +L++G+    A L L Y +P + ++E+ K+ F  N+FSVTRQ+ Y+   +   +D+ 
Sbjct  102   VLRLLKKGLDVDDAFLSLMYPAPLASSSEKVKKDFSANLFSVTRQVCYSNANPLEEIDMV  161

Query  143   LFINGLPVITIELKNHFTGQTTA-DAVEQYKKDRNPRELLFSFKRCIVHFAVDDQTVQFC  201
             LFING+P+IT+ELKN  TGQ +  ++  QY+ DR++ + L++F RC+VH AVD + V   
Sbjct  162   LFINGIPLITLELKNPWTGQNAVYHGQKQYRDDRDANQPLLNFARCLVHMAVDTDEVYMT  221

Query  202   TKLCGKASWFLPFNKGYHDGAGNPPNPEGIMTDYLWKDILTKKKLSRIIENYAQVVVEEN  261
             TKL GK + FLPFNKG++ G GNP NP+G  T YLW++++ K  ++ II+++ ++    +
Sbjct  222   TKLAGKNTFFLPFNKGFNFGKGNPINPHGHKTAYLWQEVFRKESIANIIQHFIRLDGSSK  281

Query  262   PETRKKSVKQIWPRYHQLDCVEKLLADIRQYGVGKRYLIQHSAGSGKSNSIAWLAHQLI-  320
              +  K+++  + PRYHQ+D V +L+ +    GVG+ YLIQHSAGSGKSNSI+W A QLI 
Sbjct  282   KQLDKRTL--FFPRYHQMDVVRRLVDHCSVNGVGQTYLIQHSAGSGKSNSITWAAYQLIE  339

Query  321   ---------GLERDGRPMIDSVIVVTDRRILDKQIRDTIKQFMQVKNTVVWARHSGDLKK  371
                      G      P++DSVIVVTDRR+LDKQ+RD IK+F +VKN V  A  S++LK 
Sbjct  340   TYPISDDLPGSRGKEVPLFDSVIVVTDRRLLDKQLRDNIKEFSEVKNIVAPAFKSSELKS  399

Query  372   AIQDGKRIIVTTVEKFPYISQEIGQEHMNHTFAIIIDEAHSGQSGRNAASMNLALSGMAS  431
             A+++GK+II+TT++KFPYI + I+ +  ++ FA+IIDEAHS+Q G+N   +N A+ G  S
Sbjct  400   ALENGKKIIITTIQKFPYIVDGIA-DLSDRRFAVIIDEAHSSQDGHNQDKLNEAM-GFVS  457

Query  432   DSELDNEDKINAMVEGRKLVKTASYFAFTATPKNKTEEVFGTPYEEDGKIKHRPFHVYTM  491
             +  LD   K       RK+   ASYFAFTATPKN T E FG   + ++     PFH+Y+M
Sbjct  458   EDVLD---KALQSAKNRKMRSNASYFAFTATPKNTTLEKFG---QRQADGTYVPFHLYSM  511

Query  492   KQAIQEGFILDVLKNYVTIDSWYKIAKKVEDDPMFDKKRAQKKLRSFVEGNPDVIAKKAA  551
             KQAI+EGFILDV+ NY T  S Y I K ++D+P FD K+AQK+LR++VE++ + I  KA 
Sbjct  512   KQAIEEGFILDVIANYTTYKSYYEIEKSIQDNPEFDSKKAQKRLRAYVEASQETIDTKAE  571

Query  552   MMVDHFHEQIIARKKLGGQSRAMVVTASIPRCIETYYAVTQCLADRHSPYKAIIAFSGEC  611
             +M++HF  +++  KKL G++++MVVT +I   I  Y A+T  L    +P+K  IAFSG  
Sbjct  572   IMLEHFIKHVVNGKKLKGKGKGMVVTQNIESAIRYYRALTIQLNKMGNPFKVAIAFSGSK  631

Query  612   SYHGQEPVLTSAEMNGFPDAK-----------------IPQKFKKDPYRLLVVADMFQTG  654
               +G E   T A++NGFP++                  IP+   +D+YRLLVVA+ + TG
Sbjct  632   EVDGIE--YTEADINGFPEGDTKDYFDVNYKRKEPDSPIPKHVDQDAYRLLVVANKYLTG  689

Query  655   FDEPLLQTMYVDKPLSDIAAVQTLSRLNRAAP--GK--DEVYVLDFANKAETIEKAFSRF  710
             FD+P L +MYVDK L+ +  VQ+LSRLNR+AP  GK  ++++VLDF N  + I  AF  F
Sbjct  690   FDQPKLCAMYVDKKLASVLCVQALSRLNRSAPKYGKKTEDLFVLDFFNSVDDIKTAFDPF  749

Query  711   YRTTILSGETDPNKLYDLISLMEGYQVYDHSDVDKVVDLFLNGGERDRLDPLLDPCVALY  770
             Y +T LS  TD N L +L   M++  VY+  +V+     F++G E + L P++D   A +
Sbjct  750   YTSTTLSEATDVNVLHELKDDMDDTGVYEWFEVEEFNKRFFEGREAQDLSPIIDIAAARF  809

Query  771   NQ---LETDDQIQFKSAAKAFVRTYGFLGSILPYGNAAWEKLSIFLNLLIPKLP--SPQT  825
             N+   LE + +++FK  AK FV+ YG ++SI+PY    WEKL  FL++LIPKL+   P+ 
Sbjct  810   NHELELENEFKVDFKVKAKQFVKIYGQIASIMPYEVVQWEKLFWFLKFLIPKLSVEDPDK  869

Query  826   DDLSEGILSAVDLDSYR-NEAREAVAIKLEDEDAEIDP-VPTGKVGHIVEPEMDPLSQII  883
             + L +++L +VDL SY  +  +   +I L+D ++E+DP  P  + +   E+E DPL +II
Sbjct  870   EAL-DSLLDSVDLSSYGLQRVKLNHSIELDDSETELDPQNPNPRGAYGPEAEKDPLDEII  928

Query  884   SEFNDM-FGNIQWNDADNVQQ-QLLRIPVMVSHDEKYRNAMKNSDEQEARTEG-ERALQQ  940
               FN+  F    W+ + + Q+ +++ I+  + ++  +    +N+ + ++R  + E+ L++
Sbjct  929   KIFNERWFQG--WSATPEEQRVKFVNIAESIRNHPDFEAKYQNNADPHTRELAFEKMLKE  986

Query  941   VIFSIMADNMELFKQFQDNPSFK-KWLTDM  969
             +++    D++EL+K F ++P+FK  W   M
Sbjct  987   IMLQRRKDELELYKLFAQDPAFKASWTQSM  1016

72) BAST_1688 in NC_018720


> EU272902|14|G13|167832520|ACA01830.1|Vibrio_cholerae_Amazonia_3509|-|13968..17036|-|VPI2_0013c|type 
I restriction enzyme 
HsdR
Length=1022

 Score =  574 bits (2169),  Expect = 6e-165, Method: Compositional matrix adjust.
 Identities = 416/996 (42%), Positives = 644/996 (65%), Gaps = 65/996 (6%)

Query  21    NQNGYEQGTNDDYSKEYAVDETRLF-HFLNDTQPQETAKLGINSSAAKKRQFLNRLSAEI  79
             N++ Y  G+  D+ K+YA+D TRLF +FL+DTQ+ E  KL   S+   +R++L+R+   I
Sbjct  39    NNDLYLIGSPSDFDKQYALD-TRLFWQFLEDTQASELEKLKRTSPHDWQRKILERFDRMI  97

Query  80    TKRGIIDVLRNGLHVYPADL-IMFCFTPTENNERSKEMFEKNIFSVTRQLRYSSDTTKLA  138
              ++G++ +L++GL+V  A L +M+    + ++E+ K  F  N+FSVTRQ+ YS+      
Sbjct  98    MRHGVLRLLKKGLDVDDAFLSLMYPAPLASSSEKVKKDFSANLFSVTRQVCYSNANPLEE  157

Query  139   LDLCLFINGLPIITIELKNHFTGQTTT-DAVEQYKKDRSPRDTLFSFKRCMVHFAVDDQT  197
             +D+ LFING+P+IT+ELKN  TGQ +  ++  QY+ DR + + L++F RC+VH AVD + 
Sbjct  158   IDMVLFINGIPLITLELKNPWTGQNAVYHGQKQYRDDRDANQPLLNFARCLVHMAVDTDE  217

Query  198   LMFCTKLAEKDSWFLPFNKGYNDGAGNPPNPDGIMTDYLWKDILTKQKLSRIIENYAQVV  257
             +   TKLA K++ FLPFNKG+N G GNP NP+G  T YLW++++ K+ ++ II+++ ++ 
Sbjct  218   VYMTTKLAGKNTFFLPFNKGFNFGKGNPINPHGHKTAYLWQEVFRKESIANIIQHFIRLD  277

Query  258   VDEDPDTHKKSEKQIWPRYHQLDCVEKLLTDVKENGVGKRYLIQHSAGSGKSNSIAWLAH  317
                  + +K++   + PRYHQ+D V +L+ +   NGVG+ YLIQHSAGSGKSNSI+W A 
Sbjct  278   GSSKKQLDKRT--LFFPRYHQMDVVRRLVDHCSVNGVGQTYLIQHSAGSGKSNSITWAAY  335

Query  318   QLI----------GLEKDGRPMIDSVIVVTDRRILDRQIRDTIRQFMQVRNTVVWAQHSG  367
             QLI          G      P++DSVIVVTDRR+LD+Q+RD I++F +V+N V  A  S+
Sbjct  336   QLIETYPISDDLPGSRGKEVPLFDSVIVVTDRRLLDKQLRDNIKEFSEVKNIVAPAFKSS  395

Query  368   DLKKAIQDGKRIIVTTIEKFPYISQEIGQEHLDNRFAIIIDEAHSGQSGRNSANMNLALS  427
             +LK A+++GK+II+TTI+KFPYI + I+ +  D RFA+IIDEAHS+Q G+N  ++N A+ 
Sbjct  396   ELKSALENGKKIIITTIQKFPYIVDGIA-DLSDRRFAVIIDEAHSSQDGHNQDKLNEAM-  453

Query  428   GMASDDEMDNEDKINAIVEGRKLVKTASYFAFTATPKNKTEEVFGTPYEADGVVKHKPFH  487
             G  S+D +D   K       RK+   ASYFAFTATPKN T E FG   +ADG     PFH
Sbjct  454   GFVSEDVLD---KALQSAKNRKMRSNASYFAFTATPKNTTLEKFGQR-QADGT--YVPFH  507

Query  488   VYTMKQAIQEGFILDVLKNYTTIDSWYKIAKKVEDDPMFDKKRTQKKLRSFVEGNSDVIA  547
             +Y+MKQAI+EGFILDV+ NYTT  S Y I K ++D+P FD K++QK+LR++VE++ + I 
Sbjct  508   LYSMKQAIEEGFILDVIANYTTYKSYYEIEKSIQDNPEFDSKKAQKRLRAYVEASQETID  567

Query  548   QKAAMMVDHFHEQIIAKKKLNGRSRAMVVTASIPRCIETYQAINKCLAERHSPYKAIIAF  607
              KA +M++HF  +++  KKL+G++++MVVT +I   I  Y+A+   L    +P+K  IAF
Sbjct  568   TKAEIMLEHFIKHVVNGKKLKGKGKGMVVTQNIESAIRYYRALTIQLNKMGNPFKVAIAF  627

Query  608   SGEYRYNGQKLALTSADINGF-----------------PDARIPKEFTKDPYRLLVVADM  650
             SG    +G  +  T ADINGF                 PD+ IPK+  +D+YRLLVVA+ 
Sbjct  628   SGSKEVDG--IEYTEADINGFPEGDTKDYFDVNYKRKEPDSPIPKHVDQDAYRLLVVANK  685

Query  651   FQTGFDEPLLQTMYVDKPLYDIAAVQTLSRLNRAAP--GK--SEVYVLDFANKTQTIQDA  706
             + TGFD+P L +MYVDK L  +  VQ+LSRLNR+AP  GK   +++VLDF N  + I+ A
Sbjct  686   YLTGFDQPKLCAMYVDKKLASVLCVQALSRLNRSAPKYGKKTEDLFVLDFFNSVDDIKTA  745

Query  707   FSKFYRTTILSGETDPNKLYDLITIMENYQVYGSNDVKSVVYLFIGGAERDRLDPLLDPC  766
             F  FY +T LS  TD N L +L   M++  VY   +V      F+ G E + L P++D  
Sbjct  746   FDPFYTSTTLSEATDVNVLHELKDDMDDTGVYEWFEVEEFNKRFFEGREAQDLSPIIDIA  805

Query  767   VITYE-DLGMDDQIK--FKSAAKSFVRTYGFLSSILPYGNLDWEKLSIFLNLLIPKLPSP  823
                ++ +L +++++K  FK  AK FV+ YG ++SI+PY  ++WEKL  FL++LIPKL+  
Sbjct  806   AARFNHELELENEFKVDFKVKAKQFVKIYGQIASIMPYEVVQWEKLFWFLKFLIPKLSVE  865

Query  824   REDDLSVE-ISSTIDLDSYRNEALEAV----AIKLEDENAEIAP-VPAGKAGHIVEPEMD  877
               D  +++ +  ++DL SY   +L+ V    +I L+D ++E+ P  P  +++   E+E D
Sbjct  866   DPDKEALDSLLDSVDLSSY---GLQRVKLNHSIELDDSETELDPQNPNPRGAYGPEAEKD  922

Query  878   PLSQIISEFND-LFGNIHWKDADNVQK-QLLRIPTMVSRDEKYQNAMRNSDEQEARTES-  934
             PL +II  FN+  F    W  + + Q+ +++ I+  +  +  ++   +N+ + ++R  + 
Sbjct  923   PLDEIIKIFNERWFQG--WSATPEEQRVKFVNIAESIRNHPDFEAKYQNNADPHTRELAF  980

Query  935   ERSLQKVIFSIMSDNMELFKQFQDNPSFK-RWLNSM  969
             E+ L+ +++    D++EL+K F ++P+FK  W +SM
Sbjct  981   EKMLKEIMLQRRKDELELYKLFAQDPAFKASWTQSM  1016

73) Thet_1691 in NC_014538


> EU272902|14|G13|167832520|ACA01830.1|Vibrio_cholerae_Amazonia_3509|-|13968..17036|-|VPI2_0013c|type 
I restriction enzyme 
HsdR
Length=1022

 Score =  567 bits (2141),  Expect = 9e-163, Method: Compositional matrix adjust.
 Identities = 421/991 (43%), Positives = 636/991 (65%), Gaps = 65/991 (6%)

Query  25    YEQGSNADYNRDYAIDETRLFR-FLSATQPDEMEKLGVFKSDLKKAQFLNRLRGEIAKRG  83
             Y  GS +D++++YA+D TRLF+ FL  TQ+ E+EKL    ++  + ++L+R+   I ++G
Sbjct  43    YLIGSPSDFDKQYALD-TRLFWQFLEDTQASELEKLKRTSPHDWQRKILERFDRMIMRHG  101

Query  84    IIDVLRNGIKVYPADLVMFYLTP-SERNIKAKALFEQNIFSVTRQLQYSKDATRLALDLC  142
             ++ +L++G+ V  A L + Y +P +  + K K  F  N+FSVTRQ+ YS+      +D+ 
Sbjct  102   VLRLLKKGLDVDDAFLSLMYPAPLASSSEKVKKDFSANLFSVTRQVCYSNANPLEEIDMV  161

Query  143   IFINGLPVITCELKNQLTKQNVDDAVY----QYKTDRDPKELLFQFKRCMVHFAVDDARV  198
             +FING+P+IT ELKN  T QN   AVY    QY+ DRD+++ L++F RC+VH AVD   V
Sbjct  162   LFINGIPLITLELKNPWTGQN---AVYHGQKQYRDDRDANQPLLNFARCLVHMAVDTDEV  218

Query  199   KFSTKLDGKASWFLPFDKGYNDGAGNPPNSSGIMTDYLWKDILEKYMLAHIIENYAQVVE  258
               +TKL GK + FLPF+KG+N G GNP N+ G  T YLW++++ K  +A+II+++ ++  
Sbjct  219   YMTTKLAGKNTFFLPFNKGFNFGKGNPINPHGHKTAYLWQEVFRKESIANIIQHFIRLDG  278

Query  259   KVDQETKKKTYTQIFPRYHQLSAVESLLADVRHNGVGQRYLIQHSAGSGKSNSIAWLAHQ  318
                ++  K+T   +FPRYHQ+  V  L+ +   NGVGQ YLIQHSAGSGKSNSI+W A Q
Sbjct  279   SSKKQLDKRT--LFFPRYHQMDVVRRLVDHCSVNGVGQTYLIQHSAGSGKSNSITWAAYQ  336

Query  319   LVGL--------EKNGKAI--IDSVVVVTDRVILDKQIRDTIKQFMQVSSTVAWAEHSDD  368
             L+             GK +  +DSV+VVTDR +LDKQ+RD IK+F +V + VA A  S +
Sbjct  337   LIETYPISDDLPGSRGKEVPLFDSVIVVTDRRLLDKQLRDNIKEFSEVKNIVAPAFKSSE  396

Query  369   LRKAINGGKKIIITTVHKFPIILDSIGSEHKGRSFAIIIDEAHSSQSGNMSAKMNIVLSG  428
             L+ A++ GKKIIITT++KFP I+D+I+ +  +R FA+IIDEAHSSQ G+   K    L+ 
Sbjct  397   LKSALENGKKIIITTIQKFPYIVDGIA-DLSDRRFAVIIDEAHSSQDGHNQDK----LNE  451

Query  429   EVTGEEEDFEDKINRLMEGRKMLKNASYFAFTATPKNKTLEMFGIPYQDGDEIKHRPFHV  488
              +    ED  DK  +    RKM  NASYFAFTATPKN TLE FG    DG  +   PFH+
Sbjct  452   AMGFVSEDVLDKALQSAKNRKMRSNASYFAFTATPKNTTLEKFGQRQADGTYV---PFHL  508

Query  489   YTMKQAIQEGFILDVLKYYTPVDSYYRLAKTIEDDPLFDKKKAQKKLRQFVESNKFAISQ  548
             Y+MKQAI+EGFILDV+  YT   SYY + K+I+D+P FD KKAQK+LR +VE+++ +I  
Sbjct  509   YSMKQAIEEGFILDVIANYTTYKSYYEIEKSIQDNPEFDSKKAQKRLRAYVEASQETIDT  568

Query  549   KAEIMVNHFHDQVISKGKIGGKARAMVVTSSIERCIEYYYAINKCLADRRSPYKAIIAFS  608
             KAEIM++HF  +V++  K+ GK+++MVVT +IE  I YY A+   L    +P+K  IAFS
Sbjct  569   KAEIMLEHFIKHVVNGKKLKGKGKGMVVTQNIESAIRYYRALTIQLNKMGNPFKVAIAFS  628

Query  609   GEKEYGGKTLTSAAINGFPDNTIEKVF-----RKDP------------YRFLIVADMFQT  651
             G KE +G   T A INGFP+      F     RK+P            YR+L+VA+ + T
Sbjct  629   GSKEVDGIEYTEADINGFPEGDTKDYFDVNYKRKEPDSPIPKHVDQDAYRLLVVANKYLT  688

Query  652   GYDEPLLHTMYVDKMLSDIKAVQTLSRLNRSHP----QKHDTFVLDFANKTETIEAAFSK  707
             G+D+P L +MYVDK L+ +  VQ+LSRLNRS P    + +D FVLDF N  + I +AF  
Sbjct  689   GFDQPKLCAMYVDKKLASVLCVQALSRLNRSAPKYGKKTEDLFVLDFFNSVDDIKTAFDP  748

Query  708   YYRTTILSNETDPNKLYDLIAIMESHQVYESGHVDSLVELYLNGAERDRLDPILDACTAI  767
             +Y +T LS+ TD N L +L   M+   VYE  +V+ +   +++G E + L PI+D  +A 
Sbjct  749   FYTSTTLSEATDVNVLHELKDDMDDTGVYEWFEVEEFNKRFFEGREAQDLSPIIDIAAAR  808

Query  768   YK---ELDDEGKIEFKSAAKAFVRTYGFLGAILPYGNAEWEKLSIFLNLLIPKLP--SPK  822
             ++   EL++E K++FK  AK FV+ YG +++I+PY   +WEKL  FL++LIPKL+   P 
Sbjct  809   FNHELELENEFKVDFKVKAKQFVKIYGQIASIMPYEVVQWEKLFWFLKFLIPKLSVEDPD  868

Query  823   EDDLSQGILDSIDLDSYRVE-ARDSMSLVLDDADAEIGP-VPAGRVGGIVEPEMDLLSSI  880
              + L +++LDS+DL SY ++  + + S+ LDD+++E++P  P  R +   E+E D L  I
Sbjct  869   KEAL-DSLLDSVDLSSYGLQRVKLNHSIELDDSETELDPQNPNPRGAYGPEAEKDPLDEI  927

Query  881   LSSFND-LFGNIDWNDA-DNVRRQILEIPGMVTKDERYINAMKNSDKQNAR-MESERALQ  937
             +  FN+  F    W+ + ++ R ++++I+  + ++  +    +N+   ++R +  E+ L+
Sbjct  928   IKIFNERWFQG--WSATPEEQRVKFVNIAESIRNHPDFEAKYQNNADPHTRELAFEKMLK  985

Query  938   SVIFSIMADNMELFKQFNDNPSFK-KWLSDL  967
              +++    D++EL+K F ++P+FK  W   +
Sbjct  986   EIMLQRRKDELELYKLFAQDPAFKASWTQSM  1016

74) Teth514_1218 in NC_010320


> EU272902|14|G13|167832520|ACA01830.1|Vibrio_cholerae_Amazonia_3509|-|13968..17036|-|VPI2_0013c|type 
I restriction enzyme 
HsdR
Length=1022

 Score =  567 bits (2141),  Expect = 9e-163, Method: Compositional matrix adjust.
 Identities = 421/991 (43%), Positives = 636/991 (65%), Gaps = 65/991 (6%)

Query  25    YEQGSNADYNRDYAIDETRLFR-FLSATQPDEMEKLGVFKSDLKKAQFLNRLRGEIAKRG  83
             Y  GS +D++++YA+D TRLF+ FL  TQ+ E+EKL    ++  + ++L+R+   I ++G
Sbjct  43    YLIGSPSDFDKQYALD-TRLFWQFLEDTQASELEKLKRTSPHDWQRKILERFDRMIMRHG  101

Query  84    IIDVLRNGIKVYPADLVMFYLTP-SERNIKAKALFEQNIFSVTRQLQYSKDATRLALDLC  142
             ++ +L++G+ V  A L + Y +P +  + K K  F  N+FSVTRQ+ YS+      +D+ 
Sbjct  102   VLRLLKKGLDVDDAFLSLMYPAPLASSSEKVKKDFSANLFSVTRQVCYSNANPLEEIDMV  161

Query  143   IFINGLPVITCELKNQLTKQNVDDAVY----QYKTDRDPKELLFQFKRCMVHFAVDDARV  198
             +FING+P+IT ELKN  T QN   AVY    QY+ DRD+++ L++F RC+VH AVD   V
Sbjct  162   LFINGIPLITLELKNPWTGQN---AVYHGQKQYRDDRDANQPLLNFARCLVHMAVDTDEV  218

Query  199   KFSTKLDGKASWFLPFDKGYNDGAGNPPNSSGIMTDYLWKDILEKYMLAHIIENYAQVVE  258
               +TKL GK + FLPF+KG+N G GNP N+ G  T YLW++++ K  +A+II+++ ++  
Sbjct  219   YMTTKLAGKNTFFLPFNKGFNFGKGNPINPHGHKTAYLWQEVFRKESIANIIQHFIRLDG  278

Query  259   KVDQETKKKTYTQIFPRYHQLSAVESLLADVRHNGVGQRYLIQHSAGSGKSNSIAWLAHQ  318
                ++  K+T   +FPRYHQ+  V  L+ +   NGVGQ YLIQHSAGSGKSNSI+W A Q
Sbjct  279   SSKKQLDKRT--LFFPRYHQMDVVRRLVDHCSVNGVGQTYLIQHSAGSGKSNSITWAAYQ  336

Query  319   LVGL--------EKNGKAI--IDSVVVVTDRVILDKQIRDTIKQFMQVSSTVAWAEHSDD  368
             L+             GK +  +DSV+VVTDR +LDKQ+RD IK+F +V + VA A  S +
Sbjct  337   LIETYPISDDLPGSRGKEVPLFDSVIVVTDRRLLDKQLRDNIKEFSEVKNIVAPAFKSSE  396

Query  369   LRKAINGGKKIIITTVHKFPIILDSIGSEHKGRSFAIIIDEAHSSQSGNMSAKMNIVLSG  428
             L+ A++ GKKIIITT++KFP I+D+I+ +  +R FA+IIDEAHSSQ G+   K    L+ 
Sbjct  397   LKSALENGKKIIITTIQKFPYIVDGIA-DLSDRRFAVIIDEAHSSQDGHNQDK----LNE  451

Query  429   EVTGEEEDFEDKINRLMEGRKMLKNASYFAFTATPKNKTLEMFGIPYQDGDEIKHRPFHV  488
              +    ED  DK  +    RKM  NASYFAFTATPKN TLE FG    DG  +   PFH+
Sbjct  452   AMGFVSEDVLDKALQSAKNRKMRSNASYFAFTATPKNTTLEKFGQRQADGTYV---PFHL  508

Query  489   YTMKQAIQEGFILDVLKYYTPVDSYYRLAKTIEDDPLFDKKKAQKKLRQFVESNKFAISQ  548
             Y+MKQAI+EGFILDV+  YT   SYY + K+I+D+P FD KKAQK+LR +VE+++ +I  
Sbjct  509   YSMKQAIEEGFILDVIANYTTYKSYYEIEKSIQDNPEFDSKKAQKRLRAYVEASQETIDT  568

Query  549   KAEIMVNHFHDQVISKGKIGGKARAMVVTSSIERCIEYYYAINKCLADRRSPYKAIIAFS  608
             KAEIM++HF  +V++  K+ GK+++MVVT +IE  I YY A+   L    +P+K  IAFS
Sbjct  569   KAEIMLEHFIKHVVNGKKLKGKGKGMVVTQNIESAIRYYRALTIQLNKMGNPFKVAIAFS  628

Query  609   GEKEYGGKTLTSAAINGFPDNTIEKVF-----RKDP------------YRFLIVADMFQT  651
             G KE +G   T A INGFP+      F     RK+P            YR+L+VA+ + T
Sbjct  629   GSKEVDGIEYTEADINGFPEGDTKDYFDVNYKRKEPDSPIPKHVDQDAYRLLVVANKYLT  688

Query  652   GYDEPLLHTMYVDKMLSDIKAVQTLSRLNRSHP----QKHDTFVLDFANKTETIEAAFSK  707
             G+D+P L +MYVDK L+ +  VQ+LSRLNRS P    + +D FVLDF N  + I +AF  
Sbjct  689   GFDQPKLCAMYVDKKLASVLCVQALSRLNRSAPKYGKKTEDLFVLDFFNSVDDIKTAFDP  748

Query  708   YYRTTILSNETDPNKLYDLIAIMESHQVYESGHVDSLVELYLNGAERDRLDPILDACTAI  767
             +Y +T LS+ TD N L +L   M+   VYE  +V+ +   +++G E + L PI+D  +A 
Sbjct  749   FYTSTTLSEATDVNVLHELKDDMDDTGVYEWFEVEEFNKRFFEGREAQDLSPIIDIAAAR  808

Query  768   YK---ELDDEGKIEFKSAAKAFVRTYGFLGAILPYGNAEWEKLSIFLNLLIPKLP--SPK  822
             ++   EL++E K++FK  AK FV+ YG +++I+PY   +WEKL  FL++LIPKL+   P 
Sbjct  809   FNHELELENEFKVDFKVKAKQFVKIYGQIASIMPYEVVQWEKLFWFLKFLIPKLSVEDPD  868

Query  823   EDDLSQGILDSIDLDSYRVE-ARDSMSLVLDDADAEIGP-VPAGRVGGIVEPEMDLLSSI  880
              + L +++LDS+DL SY ++  + + S+ LDD+++E++P  P  R +   E+E D L  I
Sbjct  869   KEAL-DSLLDSVDLSSYGLQRVKLNHSIELDDSETELDPQNPNPRGAYGPEAEKDPLDEI  927

Query  881   LSSFND-LFGNIDWNDA-DNVRRQILEIPGMVTKDERYINAMKNSDKQNAR-MESERALQ  937
             +  FN+  F    W+ + ++ R ++++I+  + ++  +    +N+   ++R +  E+ L+
Sbjct  928   IKIFNERWFQG--WSATPEEQRVKFVNIAESIRNHPDFEAKYQNNADPHTRELAFEKMLK  985

Query  938   SVIFSIMADNMELFKQFNDNPSFK-KWLSDL  967
              +++    D++EL+K F ++P+FK  W   +
Sbjct  986   EIMLQRRKDELELYKLFAQDPAFKASWTQSM  1016

75) Belba_0345 in NC_018010


> EU272902|14|G13|167832520|ACA01830.1|Vibrio_cholerae_Amazonia_3509|-|13968..17036|-|VPI2_0013c|type 
I restriction enzyme 
HsdR
Length=1022

 Score =  565 bits (2132),  Expect = 5e-162, Method: Compositional matrix adjust.
 Identities = 418/1018 (42%), Positives = 658/1018 (65%), Gaps = 86/1018 (8%)

Query  20    NDNGYLLRENTAYDNVACLDSALLFEFLEATQPKSVAKLKTYHKDLYEQKIIKRLNDQIQ  79
             N++ YL+   + +D+   LD+ L+ +FLE TQ+  + KLK    +  ++KI+ R++  I 
Sbjct  39    NNDLYLIGSPSDFDKQYALDTRLFWQFLEDTQASELEKLKRTSPHDWQRKILERFDRMIM  98

Query  80    AKGVIEVLRKG--ITDGFTDTKLHLFYDKPVSNYNVSASILYQANSFSVMRQVYFSPQNK  137
               GV+ +L+KG  + D+F    L L Y  P+++ +      + AN FSV RQV +S  N 
Sbjct  99    RHGVLRLLKKGLDVDDAF----LSLMYPAPLASSSEKVKKDFSANLFSVTRQVCYSNANP  154

Query  138   -KSLDLMLFINGIPIISFELKNELTKQN-VQHAIKQYKTDRDPNEELFRLGRLMVNFAVD  195
                +D++LFINGIP+I++ELKN  T QN V H+ KQY+ DRD+N+ L+ ++R +V+ AVD
Sbjct  155   LEEIDMVLFINGIPLITLELKNPWTGQNAVYHGQKQYRDDRDANQPLLNFARCLVHMAVD  214

Query  196   TEEVWMCTQLKKEKSYFLPFnkgyn-ngagnppnggIKTDYLWKEVLTKSSLTDVIQNFC  254
             T+EV M T+L   +++FLPFNKG+N   +      G KT YLW+EV+ K S++++IQ+F 
Sbjct  215   TDEVYMTTKLAGKNTFFLPFNKGFNFGKGNPINPHGHKTAYLWQEVFRKESIANIIQHFI  274

Query  255   QLITEEKEYLDEKGKVRTRKEKKLIFPRYHQLVAVRNLLADAQEKGSGQKYLIQHSAGSG  314
             +L    K  LD +          L+FPRYHQ+  VR L+ +   +G GQ YLIQHSAGSG
Sbjct  275   RLDGSSKKQLDKRT---------LFFPRYHQMDVVRRLVDHCSVNGVGQTYLIQHSAGSG  325

Query  315   KSNSISWLAHQLV-------GLHDKSGQN-NIFDTVIVVTDRRVLDAQIRENIKQYQQVK  366
             KSNSI+W A QL+       +L +  G++  +FD+VIVVTDRR+LD Q+R+NIK++ +VK
Sbjct  326   KSNSITWAAYQLIETYPISDDLPGSRGKEVPLFDSVIVVTDRRLLDKQLRDNIKEFSEVK  385

Query  367   GVVEAITEGSKQLKQALEEGKKIIITTIQKFPHIVEDIGDLPGNNFAIIIDEAHSSLSGQ  426
              +V +   +S +LK ALE+GKKIIITTIQKFP IV++I+DL++  FA+IIDEAHSS  G+
Sbjct  386   NIVAPAFKSS-ELKSALENGKKIIITTIQKFPYIVDGIADLSDRRFAVIIDEAHSSQDGH  444

Query  427   MARKLNETLSSSVQTGHALSQHLKEEEEFKTEDGDTLTGEDLIAELIKSRKLLPNASYFA  486
                KLNE+++    + + L + L+                       K+RK+ +NASYFA
Sbjct  445   NQDKLNEAMG--FVSEDVLDKALQSA---------------------KNRKMRSNASYFA  481

Query  487   FTATPKNKTLELFGVPYQDDGKTKFRAFHLYSMKQAIEEGFIMDVLQNYTTYQSYYALLK  546
             FTATPKN TLE FG   Q ++   + +FHLYSMKQAIEEGFI+DV+ NYTTY+SYY + K
Sbjct  482   FTATPKNTTLEKFG---QRQADGTYVPFHLYSMKQAIEEGFILDVIANYTTYKSYYEIEK  538

Query  547   KIEDDPEYDKLKAQKKLKHYVESHEHAIKKKAILIIEHFMENVIRKKRIGGFAKAMLVTS  606
              I+D+PE+D  KAQK+L+ YVE+ +++I  KA +++EHF+ +V+  K++ G +K+M+VT 
Sbjct  539   SIQDNPEFDSKKAQKRLRAYVEASQETIDTKAEIMLEHFIKHVVNGKKLKGKGKGMVVTQ  598

Query  607   SRANAVKYKKAFDDYLLKINSPFLSVVAFSG--EIDGQ--TEASLNGFSSAN--------  654
             +  +A++Y +A+   L K+ +PF   +AFSG  E+DG   TEA +NGF+ ++        
Sbjct  599   NIESAIRYYRALTIQLNKMGNPFKVAIAFSGSKEVDGIEYTEADINGFPEGDTKDYFDVN  658

Query  655   ---------IPSEFKKNEYRFLLVANKFQTGFDQPLLHTMYVDKKLGGVNAVQTLSRLNR  705
                      IP +  ++ YR+L+VANK+ TGFDQP L +MYVDKKL++V  VQ+LSRLNR
Sbjct  659   YKRKEPDSPIPKHVDQDAYRLLVVANKYLTGFDQPKLCAMYVDKKLASVLCVQALSRLNR  718

Query  706   SHP----LKKDTFVLDFANSAEDIENAFKPYFESTILGEATDPNKLFDLQDALDNFQVYT  761
             S P       D FVLDF NS +DI  AF P++ ST L+EATD N L +L+D +D+  VY 
Sbjct  719   SAPKYGKKTEDLFVLDFFNSVDDIKTAFDPFYTSTTLSEATDVNVLHELKDDMDDTGVYE  778

Query  762   NDQVYEFSEKILANVPVDQLHAMLDTSTEIFRKDLSEEQQ--ADFRAKVKTYVRLYIFLS  819
               +V EF+ +++     ++L +++D ++  F  +L  E++   DF+ K K +V++Y  ++
Sbjct  779   WFEVEEFNKRFFEGREAQDLSPIIDIAAARFNHELELENEFKVDFKVKAKQFVKIYGQIA  838

Query  820   QIVPFENPYLERLYIFLNHLQSKLGGDTP-IDLAQGILDNIDMDSYRLQ-LEATTSIVME  877
              I+P+E    E+L+ FL+ L +KL+ + P  +  +++LD++D+ SY LQ +    SI ++
Sbjct  839   SIMPYEVVQWEKLFWFLKFLIPKLSVEDPDKEALDSLLDSVDLSSYGLQRVKLNHSIELD  898

Query  878   QGQ-DLNPIPTDMRGG-SSDAEKDRLSNILKTFNDR-YGTQFEDADKVRQMAENIATDVA  934
             +++ +L+P   + RG+ +++AEKD L +I+K FN+R +      ++  R    NIA  + 
Sbjct  899   DSETELDPQNPNPRGAYGPEAEKDPLDEIIKIFNERWFQGWSATPEEQRVKFVNIAESIR  958

Query  935   KNKELISSIQHSDDQNAR-ITSDKVVGEELLKHITTNFDLYKLYSDNKEFKEDFTAMM  991
             ++ ++ +  Q++ D ++R ++ +K++ E +L++   +++LYKL++++  FK   T  M
Sbjct  959   NHPDFEAKYQNNADPHTRELAFEKMLKEIMLQRRKDELELYKLFAQDPAFKASWTQSM  1016

76) BN865_13620c in NC_022132


> EU272902|14|G13|167832520|ACA01830.1|Vibrio_cholerae_Amazonia_3509|-|13968..17036|-|VPI2_0013c|type 
I restriction enzyme 
HsdR
Length=1022

 Score =  540 bits (2039),  Expect = 1e-154, Method: Compositional matrix adjust.
 Identities = 401/1000 (41%), Positives = 654/1000 (66%), Gaps = 65/1000 (6%)

Query  19    ENHAYIKRTNENFDKNLCIDTEFFENFLQATQSVALEELKKRCGQNYKKELFDRIFSQIK  78
             +N+ Y+  +  +FDK+  +DT +F +FL+ TQ+  LE LK+   ++ ++ +++R+   I 
Sbjct  39    NNDLYLIGSPSDFDKQYALDTRLFWQFLEDTQASELEKLKRTSPHDWQRKILERFDRMIM  98

Query  79    TKGIVKALQGYVEIKGIKFYLAFAKPNTNANAQSLRNYEQNTLSIIRQLYYSTQNK-NSI  137
               G+++ L+  +++ +  + L ++ P ++++ +  +++  N +S+ RQ+ YS  N  + I
Sbjct  99    RHGVLRLLKKGLDVDDAFLSLMYPAPLASSSEKVKKDFSANLFSVTRQVCYSNANPLEEI  158

Query  138   DMVLFLNGLPLITIELKNHFTGQN-VFHAIEQYKKDRNPKETL--FNHTIVHFALDHDLC  194
             DMVLF+NG+PLIT+ELKN  TGQN V+H+  QY+ DR++++ L  F + +VH A+D D  
Sbjct  159   DMVLFINGIPLITLELKNPWTGQNAVYHGQKQYRDDRDANQPLLNFARCLVHMAVDTDEV  218

Query  195   YMSTRLDQSATTFLPFNLGLNNGSGKIGLANGAGNPPSDGIKTAYLWEKIFKKDTLLNLL  254
             YM+T+L    T FLPFN G+N G G+           ++G KTAYLW+ +F+K+++ N++
Sbjct  219   YMTTKLAGKNTFFLPFNKGFNFGKGN--------PINPHGHKTAYLWQEVFRKESIANII  270

Query  255   FNFVQV---IKKE-NKEIIIFPRYHQFDVVEKLLAHAKEKGAGQRYLIQHSAGSGKSNSI  310
              +F+++    KK+ +K  ++FPRYHQ DVV +L+ H   +G GQ YLIQHSAGSGKSNSI
Sbjct  271   QHFIRLDGSSKKQLDKRTLFFPRYHQMDVVRRLVDHCSVNGVGQTYLIQHSAGSGKSNSI  330

Query  311   SWLAHHLVSL----HKLEENSFKNI--FDSIIVVTDRKVLDSQIRENVKAFSHTKNLVEV  364
             +W A +L+      + L  +  K++  FDS+IVVTDR++LD Q+R+N+K FS+ KN+V  
Sbjct  331   TWAAYQLIETYPISDDLPGSRGKEVPLFDSVIVVTDRRLLDKQLRDNIKEFSEVKNIVAP  390

Query  365   ITHGSKQLKEALEEGKKIIITTIQKFPYILNEVKSLKSKTFAIIIDEAHSSQSGSNAQKM  424
              +  S +LK ALE+GKKIIITTIQKFPYI++ +  L  + FA+IIDEAHSSQ G N +K+
Sbjct  391   -AFKSSELKSALENGKKIIITTIQKFPYIVDGIADLSDRRFAVIIDEAHSSQDGHNQDKL  449

Query  425   AEAIRDKSGDESQNLEDEILEIIKSKKLQPNASYFAFTATPKPKTLEMFGMPCEVDEGQK  484
              EA+    G  S+++ D  L+  K++K+++NASYFAFTATPK  TLE FG   + + +  
Sbjct  450   NEAM----GFVSEDVLDKALQSAKNRKMRSNASYFAFTATPKNTTLEKFG---QRQADGT  502

Query  485   FIPFHLYSMKQAIEEGFILDVLKGYTTYKSYYKIISCTNDNPKYDKKRANAKLKAYVQNN  544
             ++PFHLYSMKQAIEEGFILDV+  YTTYKSYY I    +DNP +D K+A+ +L+AYV+ +
Sbjct  503   YVPFHLYSMKQAIEEGFILDVIANYTTYKSYYEIEKSIQDNPEFDSKKAQKRLRAYVEAS  562

Query  545   IRTIEQKSQIMCEHFFQNSFK--KINGKAKAMIVTSSRENAVKYYLVFREYLRKNYPHFK  602
               TI+ K++IM EHF+++  +  K++GK+K+M+VT + E+A++YY  +   L K    FK
Sbjct  563   QETIDTKAEIMLEHFIKHVVNGKKLKGKGKGMVVTQNIESAIRYYRALTIQLNKMGNPFK  622

Query  603   TIVAFSGEINLEGEIYSESGLNGFSEGVLKD----EFKK-------------DEYRFLIV  645
               +AFSG  +++G  Y+E+++NGF+EG  KD    ++K+             D YR+L+V
Sbjct  623   VAIAFSGSKEVDGIEYTEADINGFPEGDTKDYFDVNYKRKEPDSPIPKHVDQDAYRLLVV  682

Query  646   AEKYQTGFDEPLLHTMYVDKTLSGVSAVQTLSRLNRTC----KNKEDTFVLDFANTHEDI  701
             A+KY TGFD+P L +MYVDK L++V  VQ+LSRLNR+     K+ ED FVLDF N+ +DI
Sbjct  683   ANKYLTGFDQPKLCAMYVDKKLASVLCVQALSRLNRSAPKYGKKTEDLFVLDFFNSVDDI  742

Query  702   AKAFSVFYEQTYLNEPTDDNRIFDLKANLSEYEIYTQEEIDDFTNAIL-GREKENVIHSK  760
               AF  FY  T L+E+TD N + +LK ++ +  +Y   E+++F + ++ GRE ++ + + 
Sbjct  743   KTAFDPFYTSTTLSEATDVNVLHELKDDMDDTGVYEWFEVEEFNKRFFEGREAQD-LSPI  801

Query  761   LDIMLARFDEKSDDE---KLDFYSKAKTYLKEYSFLAQILPYEDVelekl-yillkklas  816
             +DI  ARF++  + E   K+DF  KAK ++K Y+ +A I+PYE V+ EKL  +L   ++ 
Sbjct  802   IDIAAARFNHELELENEFKVDFKVKAKQFVKIYGQIASIMPYEVVQWEKLFWFLKFLIPK  861

Query  817   kiilpkSQDLAKGILDNVDFDSYRLQLDK-TQDIFL-QGNGELKPSFADGSSK-SVETEL  873
               +    ++   ++LD+VD+ SY LQ  K  + I L +++ EL P  ++  +  + E+E 
Sbjct  862   LSVEDPDKEALDSLLDSVDLSSYGLQRVKLNHSIELDDSETELDPQNPNPRGAYGPEAEK  921

Query  874   EELSNIIKDFNNKYANIDFNESDKIAKILYDIKDDMVKNERILES--LNKSDMQNSRIEF  931
             + L +IIK FN++  + + + +    ++ +    + ++N+  +E+   N++D +   + F
Sbjct  922   DPLDEIIKIFNERWFQ-GWSATPEEQRVKFVNIAESIRNHPDFEAKYQNNADPHTRELAF  980

Query  932   NMLLEDKIQDILNLNLELFKQFNQNNEFKDKIANTMFNMI  971
             + +L + + +  + +LEL+K F Q+  FK   +++M  M+
Sbjct  981   EKMLKEIMLQRRKDELELYKLFAQDPAFKASWTQSMQRMV  1020

77) CJJ81176_0780 in NC_008787


> EU272902|14|G13|167832520|ACA01830.1|Vibrio_cholerae_Amazonia_3509|-|13968..17036|-|VPI2_0013c|type 
I restriction enzyme 
HsdR
Length=1022

 Score =  536 bits (2022),  Expect = 2e-153, Method: Compositional matrix adjust.
 Identities = 400/999 (41%), Positives = 654/999 (66%), Gaps = 67/999 (6%)

Query  19    ENHAYIKRTNENYDKNLCLDVELFENFLQATQSVALEELKKRCGQNYKKELFDRIFSQIK  78
             +N+ Y+  +  ++DK+  LD  LF +FL+ TQ+  LE LK+   ++ ++ +++R+   I 
Sbjct  39    NNDLYLIGSPSDFDKQYALDTRLFWQFLEDTQASELEKLKRTSPHDWQRKILERFDRMIM  98

Query  79    AKGIVKALQGYVEIKGIKIYLAFAKPNTNANEESVKKYEQNTLSIIRQLYYSTQNK-NSL  137
               G+++ L+  +++ +  + L ++ P ++++E   K +  N +S+ RQ+ YS  N  + +
Sbjct  99    RHGVLRLLKKGLDVDDAFLSLMYPAPLASSSEKVKKDFSANLFSVTRQVCYSNANPLEEI  158

Query  138   DIVIFLNGLPLITIELKNHFTGQN-VFHAIKQYKKDRNPKEAIFNYT--IVHFALDHDLC  194
             D+V+F+NG+PLIT+ELKN  TGQN V+H+ KQY+ DR+++++++N++  +VH A+D D  
Sbjct  159   DMVLFINGIPLITLELKNPWTGQNAVYHGQKQYRDDRDANQPLLNFARCLVHMAVDTDEV  218

Query  195   YMSTKLDQDATTFLPFNLGLNNGSGKIGLANGAGNPPSDGIKTAYLWEKIFKKDTLLNLF  254
             YM+TKL    T FLPFN G+N G G+           ++G KTAYLW+ +F+K+++ N++
Sbjct  219   YMTTKLAGKNTFFLPFNKGFNFGKGN--------PINPHGHKTAYLWQEVFRKESIANII  270

Query  255   FNFVQVVKKKNEEI----IIFPRYHQFDVVEKLLAHAKENGTGQRYLIQHSAGSGKSNSI  310
              +F+++    + ++    ++FPRYHQ DVV +L+ H   NG GQ YLIQHSAGSGKSNSI
Sbjct  271   QHFIRLDGSSKKQLDKRTLFFPRYHQMDVVRRLVDHCSVNGVGQTYLIQHSAGSGKSNSI  330

Query  311   SWLAHNLVSLHRLEKNI----------FDSIIVVTDRKVLDSQIRENVKSFSQTKNLVEA  360
             +W A +L+    +  ++          FDS+IVVTDR++LD Q+R+N+K FS+ KN+V +
Sbjct  331   TWAAYQLIETYPISDDLPGSRGKEVPLFDSVIVVTDRRLLDKQLRDNIKEFSEVKNIVAP  390

Query  361   ITHGSKQLKNALEEGKKIIITTIQKFPFILDEIKTLKSKTFAIIIDEAHSSQSGSNAQKM  420
              +  S +LK+ALE+GKKIIITTIQKFP+I+D I  L  + FA+IIDEAHSSQ G N +K+
Sbjct  391   -AFKSSELKSALENGKKIIITTIQKFPYIVDGIADLSDRRFAVIIDEAHSSQDGHNQDKL  449

Query  421   AEAIRDKSGDESQNLDDEILEIIKNKKLQSNASYFAFTATPKPKTLEMFGMPCDVNGEQR  480
              EA+    G  S+++ D  L+  KN+K++SNASYFAFTATPK  TLE FG   + +++  
Sbjct  450   NEAM----GFVSEDVLDKALQSAKNRKMRSNASYFAFTATPKNTTLEKFG---QRQADGT  502

Query  481   FIPFHLYSMKQAIEEGFILDVLKGYTTYKSYYKIISCTNDNPKYDKKRANTKLKAYVQNN  540
             ++PFHLYSMKQAIEEGFILDV+  YTTYKSYY I    +DNP +D K+A+ +L+AYV+ +
Sbjct  503   YVPFHLYSMKQAIEEGFILDVIANYTTYKSYYEIEKSIQDNPEFDSKKAQKRLRAYVEAS  562

Query  541   IKTIEQKSQIMCEHFFQNSFK--KINGKAKAMIVTSSRENAVKYYLVFREYLRKNYPHFK  598
               TI+ K++IM EHF+++  +  K++GK+K+M+VT + E+A++YY  +   L K    FK
Sbjct  563   QETIDTKAEIMLEHFIKHVVNGKKLKGKGKGMVVTQNIESAIRYYRALTIQLNKMGNPFK  622

Query  599   AIVAFSGEVNLEGEIYSESGLNGFAENVLKD----EFKK-------------DEYRFLIV  641
               +AFSG  +++G  Y+E+++NGF+E   KD    ++K+             D YR+L+V
Sbjct  623   VAIAFSGSKEVDGIEYTEADINGFPEGDTKDYFDVNYKRKEPDSPIPKHVDQDAYRLLVV  682

Query  642   AEKYQTGFDEPLLHTMYVDKALSGVSAVQTLSRLNRTC----KNKENTFVLDFVNTHEDI  697
             A+KY TGFD+P L +MYVDK L++V  VQ+LSRLNR+     K+ E+ FVLDF N+ +DI
Sbjct  683   ANKYLTGFDQPKLCAMYVDKKLASVLCVQALSRLNRSAPKYGKKTEDLFVLDFFNSVDDI  742

Query  698   AKSFSVFYEQTYLSEATDDNRIFDLKANLNEYEIYTQEEIDDFANAILRKEKENIIHAKL  757
               +F  FY  T LSEATD N + +LK ++++  +Y   E+++F + ++     + + + +
Sbjct  743   KTAFDPFYTSTTLSEATDVNVLHELKDDMDDTGVYEWFEVEEFNKRFFEGREAQDLSPII  802

Query  758   DIMLDRFNQKSDDE---KLDFYNKAKTYLKEYSFLAQILPyedieleklyillkklaski  814
             DI   RFN+  + E   K+DF  KAK ++K Y+ +A I+PYE ++ EKL+ +LK L +K+
Sbjct  803   DIAAARFNHELELENEFKVDFKVKAKQFVKIYGQIASIMPYEVVQWEKLFWFLKFLIPKL  862

Query  815   ilpkSE-DLAKGILDNVDFDSYRLQLDK-TQDIVL-QGNGELKPSFADGSSK-SVEAELE  870
              +  ++ +   ++LD+VD+ SY LQ  K  + I L +++ EL P  ++  +  + EAE +
Sbjct  863   SVEDPDKEALDSLLDSVDLSSYGLQRVKLNHSIELDDSETELDPQNPNPRGAYGPEAEKD  922

Query  871   ELSNIIKDFNNKYANIDFNESDKIAKILY-DIKDDIAKNERIRETFSKSDIQNSR-IEFD  928
              L +IIK FN++  + + + +    ++ + +I + I ++  +   + ++   ++R + F+
Sbjct  923   PLDEIIKIFNERWFQ-GWSATPEEQRVKFVNIAESIRNHPDFEAKYQNNADPHTRELAFE  981

Query  929   ALLKDKIQDILELNLELFKQFNQNIEFKDKIANTMFNMV  967
              +LK+ + +    +LEL+K F Q+  FK   +++M  MV
Sbjct  982   KMLKEIMLQRRKDELELYKLFAQDPAFKASWTQSMQRMV  1020

78) Msil_3575 in NC_011666


> EU272902|14|G13|167832520|ACA01830.1|Vibrio_cholerae_Amazonia_3509|-|13968..17036|-|VPI2_0013c|type 
I restriction enzyme 
HsdR
Length=1022

 Score =  507 bits (1913),  Expect = 1e-144, Method: Compositional matrix adjust.
 Identities = 365/855 (43%), Positives = 570/855 (67%), Gaps = 51/855 (5%)

Query  1    MKTDTSEKGLEALIVAGMTGRTSAPSGGGFSEEPEPFVGLHNWLLGNPKDYDRAWTVDLV  60
            M + T+E++LEA I  G++G      + G  E P  +   +  L+G+P D+D+  ++D  
Sbjct  4    MVSKTNEQALEAAIEKGLAGICKEELALG--EAPLNYNN-DLYLIGSPSDFDKQYALDTR  60

Query  61   QLRAFVGSTQRPLVEAFDLDNDSPARQKFLARLQGEIGKRGVIDVLRHGAKHGAHDVDLF  120
             ++ F+  TQ + +E +   +    ++K+L R++  I ++GV+ +L+ G   +   + L 
Sbjct  61   LFWQFLEDTQASELEKLKRTSPHDWQRKILERFDRMIMRHGVLRLLKKGLDVDDAFLSLM  120

Query  121  YGTP-SPGNAKAAERFALNRFSVTRQLRYSRDDTAHALDLALFINGLPIATFELKNSLTK  179
            Y +P ++++ K    F+ N FSVTRQ+ YS  +  + +D+ LFING+P+ T+ELKN+ T 
Sbjct  121  YPAPLASSSEKVKKDFSANLFSVTRQVCYSNANPLEEIDMVLFINGIPLITLELKNPWTG  180

Query  180  Q-TVEDAVEQYKRDRDPREKLFEFGRCIVHLAVDDAQVKFCTQLKGKASWFLPFNKGWND  238
            Q +V ++  QY+ DRD+ + L++F+RC+VH+AVD  +V   T+L GK + FLPFNKG N 
Sbjct  181  QNAVYHGQKQYRDDRDANQPLLNFARCLVHMAVDTDEVYMTTKLAGKNTFFLPFNKGFNF  240

Query  239  GAGNPPNPTGIKTDYLWKDILTPLSLTDIIENYAQIVERKDPKTNRTKRDQLFPRFHQLD  298
            G GNP NP G KT YLW++++   S+++II+++ ++     +K +  KR  +FPR+HQ+D
Sbjct  241  GKGNPINPHGHKTAYLWQEVFRKESIANIIQHFIRLDG--SSKKQLDKRTLFFPRYHQMD  298

Query  299  VVrklladakakgagrrVLIQHSAGSGKSNSIAWLAHQLVR-------LANGGGQ---VF  348
            VVR+L+ +   +G G+  LIQHSAGSGKSNSI+W A QL+        L+ + G+   +F
Sbjct  299  VVRRLVDHCSVNGVGQTYLIQHSAGSGKSNSITWAAYQLIETYPISDDLPGSRGKEVPLF  358

Query  349  DSVVVVTDRRILDQQIRDTIKQFAQVGATVGHAEHSGDLRRFIADGKKIIITTVQKFPFI  408
            DSV+VVTDRR+LD+Q+RD IK+F++V   V+ A  S++L+  + +GKKIIITT+QKFP+I
Sbjct  359  DSVIVVTDRRLLDKQLRDNIKEFSEVKNIVAPAFKSSELKSALENGKKIIITTIQKFPYI  418

Query  409  LDDIGAQHKDRRFAILIDEAHSSQggkaaaalnaaltgaEDGNEDETVEDKINAIMEQRK  468
            +D+I A+  DRRFA++IDEAHSSQ+G     LN A+     G   E V DK      +RK
Sbjct  419  VDGI-ADLSDRRFAVIIDEAHSSQDGHNQDKLNEAM-----GFVSEDVLDKALQSAKNRK  472

Query  469  MLPNASYFAFTATPKNKTLEIFGEPFPEGDVVKHRPFHSYTMKQAIQEGFILDVLRYYTP  528
            M +NASYFAFTATPKN TLE FG+  ++G  V   PFH Y+MKQAI+EGFILDV+  YT 
Sbjct  473  MRSNASYFAFTATPKNTTLEKFGQRQADGTYV---PFHLYSMKQAIEEGFILDVIANYTT  529

Query  529  VNSYYRLVKTVDEDPEFDTKRATRKLRRYVESNDHAIRLKAEIMVDHFHEQVLALNKIGG  588
             +SYY + K+++++PEFD+K+A ++LR YVE+++++I  KAEIM++HF  +V+  +K+ G
Sbjct  530  YKSYYEIEKSIQDNPEFDSKKAQKRLRAYVEASQETIDTKAEIMLEHFIKHVVNGKKLKG  589

Query  589  QARAMVVTSGIERAIQYYQAVSAYLVERKSPYRAIVAFSGEHEFCGVKVSEASLNGFPSK  648
            ++++MVVT  IE AI+YY+A++  L    +P++  +AFSG  E  G+  +EA +NGFP  
Sbjct  590  KGKGMVVTQNIESAIRYYRALTIQLNKMGNPFKVAIAFSGSKEVDGIEYTEADINGFPEG  649

Query  649  D-----------------IVDQIETDPYRFLICADKFQTGYDQPLLHSMYVDKALSGIKA  691
            D                 I  +++ D+YR+L+ A+K+ TG+DQP L +MYVDK L+++  
Sbjct  650  DTKDYFDVNYKRKEPDSPIPKHVDQDAYRLLVVANKYLTGFDQPKLCAMYVDKKLASVLC  709

Query  692  VQTLSRLNRAHPQKY-----DTFVLDFMNDTETIRASFDKFYRTTILSDETDPNRLHDLK  746
            VQ+LSRLNR+ P KY     D FVLDF N  + I+++FD FY +T LS+ TD N LH+LK
Sbjct  710  VQALSRLNRSAP-KYGKKTEDLFVLDFFNSVDDIKTAFDPFYTSTTLSEATDVNVLHELK  768

Query  747  ATLDGYQVYDPAQIDQLVGLYLSGADRDQLDPILDACVTTYNDSLDEDGQ--VDFKGKAK  804
              +D+  VY+  +++++   ++ G + ++L PI+D   + +N+ L+ + +  VDFK KAK
Sbjct  769  DDMDDTGVYEWFEVEEFNKRFFEGREAQDLSPIIDIAAARFNHELELENEFKVDFKVKAK  828

Query  805  AFARTYAFISAILPY  819
             F + Y+ I++I+PY
Sbjct  829  QFVKIYGQIASIMPY  843

79) ICDCCJ07001_731 in NC_014802


> EU272902|14|G13|167832520|ACA01830.1|Vibrio_cholerae_Amazonia_3509|-|13968..17036|-|VPI2_0013c|type 
I restriction enzyme 
HsdR
Length=1022

 Score =  497 bits (1875),  Expect = 1e-141, Method: Compositional matrix adjust.
 Identities = 379/919 (42%), Positives = 605/919 (66%), Gaps = 67/919 (7%)

Query  14    LAFAKPNTNANEESVKKYEQNSLSIIRQLHYSTQNK-NSLDIVIFLNGLPLITIELKNHF  72
             L ++ P ++++E   K +  N +S+ RQ+ YS  N  + +D+V+F+NG+PLIT+ELKN  
Sbjct  119   LMYPAPLASSSEKVKKDFSANLFSVTRQVCYSNANPLEEIDMVLFINGIPLITLELKNPW  178

Query  73    TGQN-VFHAIKQYKKDRNPKEAIFNYT--IVHFALDNDLCYMSAKLDQDATTFLPFNLGL  129
             TGQN V+H+ KQY+ DR+++++++N++  +VH A+D D  YM++KL    T FLPFN G+
Sbjct  179   TGQNAVYHGQKQYRDDRDANQPLLNFARCLVHMAVDTDEVYMTTKLAGKNTFFLPFNKGF  238

Query  130   NNGSGKIGLANGAGNPPSDGIKTAYLWKKIFKKDTLLNLFFNFVQVVKKKNEEI----II  185
             N G G+           ++G KTAYLW+ +F+K+++ N++ +F+++    + ++    ++
Sbjct  239   NFGKGN--------PINPHGHKTAYLWQEVFRKESIANIIQHFIRLDGSSKKQLDKRTLF  290

Query  186   FPRYHQFDVVEKLLAHAKENGTGQRYLIQHSAGSGKSNSISWLAHNLVSLHRLEKNI---  242
             FPRYHQ DVV +L+ H   NG GQ YLIQHSAGSGKSNSI+W A +L+    +  ++   
Sbjct  291   FPRYHQMDVVRRLVDHCSVNGVGQTYLIQHSAGSGKSNSITWAAYQLIETYPISDDLPGS  350

Query  243   -------FDSIIVVTDRKVLDSQIRENVKSFSQTKNLVEAITHGSKQLKNALEEGKKIII  295
                    FDS+IVVTDR++LD Q+R+N+K FS+ KN+V + +  S +LK+ALE+GKKIII
Sbjct  351   RGKEVPLFDSVIVVTDRRLLDKQLRDNIKEFSEVKNIVAP-AFKSSELKSALENGKKIII  409

Query  296   TTIQKFPFILDEIKTLKSKTFAIIIDEAHSSQNGSNAQKMAEAIRDKSGDESQNLDDEIL  355
             TTIQKFP+I+D I  L  + FA+IIDEAHSSQ+G N +K+ EA+    G  S+++ D  L
Sbjct  410   TTIQKFPYIVDGIADLSDRRFAVIIDEAHSSQDGHNQDKLNEAM----GFVSEDVLDKAL  465

Query  356   EIIKNKKLQSNASYFAFTATPKPKTLEMFGMPCDVNGEQMFIPFHLYSMKQAIEEGFILD  415
             +  KN+K++SNASYFAFTATPK  TLE FG   + +++  ++PFHLYSMKQAIEEGFILD
Sbjct  466   QSAKNRKMRSNASYFAFTATPKNTTLEKFG---QRQADGTYVPFHLYSMKQAIEEGFILD  522

Query  416   VLKGYTTYKSYYKIISCTNDNPKHDKKRASVKLKAYVQNNIKTIEQKSQIMCEHFFQNSF  475
             V+  YTTYKSYY I    +DNP  D K+A  +L+AYV+ +  TI+ K++IM EHF+++  
Sbjct  523   VIANYTTYKSYYEIEKSIQDNPEFDSKKAQKRLRAYVEASQETIDTKAEIMLEHFIKHVV  582

Query  476   K--KINGKAKAMIVTSSRENAVKYYLVFREYLRKNYPHFKAIVAFSGEVNLEGEIYSESG  533
             +  K++GK+K+M+VT + E+A++YY  +   L K    FK  +AFSG  +++G  Y+E++
Sbjct  583   NGKKLKGKGKGMVVTQNIESAIRYYRALTIQLNKMGNPFKVAIAFSGSKEVDGIEYTEAD  642

Query  534   LNGFAENVLKD----EFKK-------------DEYRFLIVAEKYQTGFDEPLLHTMYVDK  576
             +NGF+E   KD    ++K+             D YR+L+VA+KY TGFD+P L +MYVDK
Sbjct  643   INGFPEGDTKDYFDVNYKRKEPDSPIPKHVDQDAYRLLVVANKYLTGFDQPKLCAMYVDK  702

Query  577   ALSGVSAVQTLSRLNRTC----KNKENTFVLDFVNTHEDIAKSFSVFYEQTYLSEATDDN  632
              L++V  VQ+LSRLNR+     K+ E+ FVLDF N+ +DI  +F  FY  T LSEATD N
Sbjct  703   KLASVLCVQALSRLNRSAPKYGKKTEDLFVLDFFNSVDDIKTAFDPFYTSTTLSEATDVN  762

Query  633   RIFDLKANLNEYEIYTQEEIDDFANAILRKEKENIIHAKLDIMLDRFNQKSDDE---KLD  689
              + +LK ++++  +Y   E+++F + ++     + + + +DI   RFN+  + E   K+D
Sbjct  763   VLHELKDDMDDTGVYEWFEVEEFNKRFFEGREAQDLSPIIDIAAARFNHELELENEFKVD  822

Query  690   FYNKAKTYLKEYSFLAQILPyedieleklyillkklaskiilpkSE-DLAKGILDNVDFD  748
             F  KAK ++K Y+ +A I+PYE ++ EKL+ +LK L +K+ +  ++ +   ++LD+VD+ 
Sbjct  823   FKVKAKQFVKIYGQIASIMPYEVVQWEKLFWFLKFLIPKLSVEDPDKEALDSLLDSVDLS  882

Query  749   SYRLQLDK-TQDIVL-QGNGELKPSFADGSSK-SVEAELEELSNIIKDFNNKYANIDFNE  805
             SY LQ  K  + I L +++ EL P  ++  +  + EAE + L +IIK FN++  + + + 
Sbjct  883   SYGLQRVKLNHSIELDDSETELDPQNPNPRGAYGPEAEKDPLDEIIKIFNERWFQ-GWSA  941

Query  806   SDKIAKILY-DIKDDIAKNERIRETFSKSDIQNSR-IEFDALLKDKIQDILELNLELFKQ  863
             +    ++ + +I + I ++  +   + ++   ++R + F+ +LK+ + +    +LEL+K 
Sbjct  942   TPEEQRVKFVNIAESIRNHPDFEAKYQNNADPHTRELAFEKMLKEIMLQRRKDELELYKL  1001

Query  864   FNQNIEFKDKIANTMFNMV  882
             F Q+  FK   +++M  MV
Sbjct  1002  FAQDPAFKASWTQSMQRMV  1020

80) Clocl_0191 in NC_016627


> EU272902|14|G13|167832520|ACA01830.1|Vibrio_cholerae_Amazonia_3509|-|13968..17036|-|VPI2_0013c|type 
I restriction enzyme 
HsdR
Length=1022

 Score =  477 bits (1799),  Expect = 1e-135, Method: Compositional matrix adjust.
 Identities = 350/835 (42%), Positives = 549/835 (66%), Gaps = 68/835 (8%)

Query  26   YIKGNPDDYNKEFAIDAKLLIDFLEDTQPKKMERLREIYKEQYQFKllsrlnrelnnrGM  85
            Y+ G+P D++K++A+D++L+ +FLEDTQ+  +E+L+    ++ Q K+L R++R +  +G+
Sbjct  43   YLIGSPSDFDKQYALDTRLFWQFLEDTQASELEKLKRTSPHDWQRKILERFDRMIMRHGV  102

Query  86   IDVLRHGIKDYGVYLDLAYFRPASKLNDEMIKLYEKNRISVTRQVHYSTKNE-NSIDMLI  144
            + +L+ G+   + +L L Y  P +  ++ + K +  N +SVTRQV YS  N  + IDM++
Sbjct  103  LRLLKKGLDVDDAFLSLMYPAPLASSSEKVKKDFSANLFSVTRQVCYSNANPLEEIDMVL  162

Query  145  CINGLPVVVLELKNPFTGQT--YQDAIMQYKKDRSPNELLFQFKKRAIVFFAVDTQEAYM  202
             ING+P++ LELKNP TGQ   Y++   QY+ DR +N+ L++F  R +V  AVDT+E YM
Sbjct  163  FINGIPLITLELKNPWTGQNAVYHGQ-KQYRDDRDANQPLLNFA-RCLVHMAVDTDEVYM  220

Query  203  TTRLSGDKTSFLPFnkgcdggkgnpdnpdgLKTDYLWEEILQKDSLMDILKRFVFIETQE  262
            TT+L+G +T FLPFNKG + GKGNP NP+G KT YLW+E+++K+S+ +I+++F+ ++   
Sbjct  221  TTKLAGKNTFFLPFNKGFNFGKGNPINPHGHKTAYLWQEVFRKESIANIIQHFIRLDGSS  280

Query  263  KKDIDGNTYTSETVIFPRYHQLDVVRKLEADAKKKGVGTNYLVQHSAGSGKTNSISWLAH  322
            KK++D       T++FPRYHQ+DVVR+L  +   +GVG  YL+QHSAGSGK+NSI+W A 
Sbjct  281  KKQLD-----KRTLFFPRYHQMDVVRRLVDHCSVNGVGQTYLIQHSAGSGKSNSITWAAY  335

Query  323  RL-------ANLHD--DNDNPVFDSVIVITDRRVLDRQLQDSIYQLEHKYGVVQKIDKDS  373
            +L        +L +  +++ P+FDSVIV+TDRR+LD+QL+D+I ++ +   +V    K S
Sbjct  336  QLIETYPISDDLPGSRGKEVPLFDSVIVVTDRRLLDKQLRDNIKEFSEVKNIVAPAFK-S  394

Query  374  NQLADALKSGTRIIISTLQKFPFIIEKVGELENRKYAVIIDEAHSSSAGENMASLREVLS  433
            ++L  AL +G +III+T+QKFP+I++ +++L +R++AVIIDEAHSS  G+N   L E ++
Sbjct  395  SELKSALENGKKIIITTIQKFPYIVDGIADLSDRRFAVIIDEAHSSQDGHNQDKLNEAMG  454

Query  434  VSTleeaakldeelegkeYDPEEEILKTIKKRGKQPNISFFAFTATPKAKTLEMFGTIGP  493
              +                D  +  L++ K+R  ++N S+FAFTATPK  TLE FG   +
Sbjct  455  FVSE---------------DVLDKALQSAKNRKMRSNASYFAFTATPKNTTLEKFGQRQA  499

Query  494  DGLPHPFHLYSMRQAIEEGFILDVLQNYVTYETYFKLAKKIEDDPTFDRAKATKAITRYV  553
            DG   PFHLYSM+QAIEEGFILDV+ NY TY +Y+ + K I+D+P FD  KA K +  YV
Sbjct  500  DGTYVPFHLYSMKQAIEEGFILDVIANYTTYKSYYEIEKSIQDNPEFDSKKAQKRLRAYV  559

Query  554  SLHPHNIAQKTEIMVEHF--RSVTRHKIGGRAKAMVVTSSRLHAVRYKHAFDEYIKKKGY  611
                + I  K+EIM+EHF  + V   K+ G++K+MVVT +   A+RY +A+   ++K G 
Sbjct  560  EASQETIDTKAEIMLEHFIKHVVNGKKLKGKGKGMVVTQNIESAIRYYRALTIQLNKMG-  618

Query  612  RDMKTLVAFSGTVKDGGVDYKESDMNGFKESE-----------------LPERFATDEYQ  654
               K  +AFSG+   +G++Y E+D+NGF E++                 +P +   D Y+
Sbjct  619  NPFKVAIAFSGSKEVDGIEYTEADINGFPEGDTKDYFDVNYKRKEPDSPIPKHVDQDAYR  678

Query  655  VLLVAEKYQTGFDQPLLHTMYVDKKLSGVKAVQTLSRLNRTCT--GK--DDTFILDFVNK  710
            +L+VA+KY TGFDQP L +MYVDKKL++V  VQ+LSRLNR+    GK  +D F+LDF N 
Sbjct  679  LLVVANKYLTGFDQPKLCAMYVDKKLASVLCVQALSRLNRSAPKYGKKTEDLFVLDFFNS  738

Query  711  AEDIQEAFKPYYQATIVEEVTEPNLLYDIETQLHSYGVYLKEELDKFAYIYFKPKDKKTS  770
             +DI+ AF P+Y +T + E T+ N+L ++  +++  GVY   E++ F   +F  ++ +  
Sbjct  739  VDDIKTAFDPFYTSTTLSEATDVNVLHELKDDMDDTGVYEWFEVEEFNKRFFEGREAQD-  797

Query  771  KDRAMLNHLIDITVERFKK---LEEQRKQDFSSQATKYIRLYSFILQITPFEDVE  822
                 L+ +IDI+  RF+    LE++ K DF  +A +++++Y+ I  I P+E V+
Sbjct  798  -----LSPIIDIAAARFNHELELENEFKVDFKVKAKQFVKIYGQIASIMPYEVVQ  847

81) BN341_p1050 in NC_019674


> EU272902|14|G13|167832520|ACA01830.1|Vibrio_cholerae_Amazonia_3509|-|13968..17036|-|VPI2_0013c|type 
I restriction enzyme 
HsdR
Length=1022

 Score =  467 bits (1761),  Expect = 8e-133, Method: Compositional matrix adjust.
 Identities = 323/748 (44%), Positives = 483/748 (65%), Gaps = 64/748 (8%)

Query  28   YHKELGLDTALLWGFLEKTQAKALEDLGQRDP-DFKQHLLEHLKQKIKEKGMLKMLKEGI  86
            ++K+ +LDT L+W FLE TQA  LE L +  P D ++ +LE++ + I   G+L++LK G+
Sbjct  51   FDKQYALDTRLFWQFLEDTQASELEKLKRTSPHDWQRKILERFDRMIMRHGVLRLLKKGL  110

Query  87   EHLGLSFKLAYNKPQTQKNLDAWQNYQSNVFSLMRQLHYSTKNN-NSVDLAIFLNGLPLF  145
            +  +  + L Y  P +  +    +++ +N+FS+ RQ+ YS  N  + +D+ +F+NG+PL+
Sbjct  111  DVDDAFLSLMYPAPLASSSEKVKKDFSANLFSVTRQVCYSNANPLEEIDMVLFINGIPLI  170

Query  146  TLELKHSLNAQNAK-HALKQY-GKRDPHEPL--FKHALAHFALDESFVYLATKLEGTRTH  201
            TLELK++  +QNA  H+ KQY + RD+++PL  F + L H A+D   VY++TKL G  T 
Sbjct  171  TLELKNPWTGQNAVYHGQKQYRDDRDANQPLLNFARCLVHMAVDTDEVYMTTKLAGKNTF  230

Query  202  FIPFNKGLNDGSAALDLECGAGNPLNPQGFKSAYLWEQVLQKDQVLNLIFNFL-------  254
            F+PFNKG+N          G GNP+NP+G K+AYLW++V++K+ + N+I +F+       
Sbjct  231  FLPFNKGFN---------FGKGNPINPHGHKTAYLWQEVFRKESIANIIQHFIRLDGSSK  281

Query  255  -QPVDRGVIFPRYHQLSAVQRLCAAVLKDRVGGRYLIEHGAGSGKSNTIAWLTYALV---  310
             Q   R ++FPRYHQ+  V+RL      + VG  YLI+H+AGSGKSN+I+W +Y L+   
Sbjct  282  KQLDKRTLFFPRYHQMDVVRRLVDHCSVNGVGQTYLIQHSAGSGKSNSITWAAYQLIETY  341

Query  311  -------GLSVDEKPLFDSVLVITDRIILDKQLQENIQSFFSIKGVVEAITEGSCQLKEA  363
                   G    E PLFDSV+V+TDR +LDKQL++NI+ F  +K +V +    S +LK A
Sbjct  342  PISDDLPGSRGKEVPLFDSVIVVTDRRLLDKQLRDNIKEFSEVKNIVAPAFK-SSELKSA  400

Query  364  LAQGKKVIIATIQKFPYILEELPSLTDKKFAIIIDEAHSSQGGAYGDALKKATGAPTQEE  423
            L +GKK+II+TIQKFPYI++ ++ L+D++FA+IIDEAHSSQ+G   D L+ A G  +++ 
Sbjct  401  LENGKKIIITTIQKFPYIVDGIADLSDRRFAVIIDEAHSSQDGHNQDKLNEAMGFVSEDV  460

Query  424  LDPDAFLLQTIKAKQFNKNASYFAFSATPKPETLELFGTKTKAEQFIPFHLYSMKQAIEE  483
            LD     LQ+ K ++   NASYFAF+ATPK  TLE FG +     ++PFHLYSMKQAIEE
Sbjct  461  LDKA---LQSAKNRKMRSNASYFAFTATPKNTTLEKFGQRQADGTYVPFHLYSMKQAIEE  517

Query  484  GFILDVLKFYTTYTFYANLVAKAPDDPLYERDPAFRKLKTYVKEHPKSIEEKTKAMLAHF  543
            GFILDV+  YTTY  Y ++     D+P ++   A ++L++YV     +I+ K+  ML HF
Sbjct  518  GFILDVIANYTTYKSYYEIEKSIQDNPEFDSKKAQKRLRAYVEASQETIDTKAEIMLEHF  577

Query  544  YTNTHH--KIGGRAKAMVITSSRQVAMRYFKAFQAQLAEEKRPHKALVAFSG--EVQGQ-  598
              +  +  K+ G++K+MV+T + + A+RY++A+  QL     P K  +AFSG  EV+G  
Sbjct  578  IKHVVNGKKLKGKGKGMVVTQNIESAIRYYRALTIQLNKMGNPFKVAIAFSGSKEVDGIE  637

Query  599  -SEASLNGFSESQT-----------------PKAFDTDAYRFLIVADKYQTGFDQPLLHT  640
             +EA +NGF+E++T                 PK  D DAYR+L+VA+KY TGFDQP L +
Sbjct  638  YTEADINGFPEGDTKDYFDVNYKRKEPDSPIPKHVDQDAYRLLVVANKYLTGFDQPKLCA  697

Query  641  MYVDKALSGVACVQTLSRLNRIHP----NKKDTCILDFENDTEKISKAFEPYYKQTFLAK  696
            MYVDK L++V CVQ+LSRLNR  P    +  D  +LDF N  + I  AF+P+Y  T L+ 
Sbjct  698  MYVDKKLASVLCVQALSRLNRSAPKYGKKTEDLFVLDFFNSVDDIKTAFDPFYTSTTLSE  757

Query  697  PSDPNKLYDLKSHLEGYGVYTQEQIEAF  724
            ++D N L +LK ++++ GVY   ++E F
Sbjct  758  ATDVNVLHELKDDMDDTGVYEWFEVEEF  785