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PAthogenisity Island DataBase (PAI DB)

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Homologs of VPI2_0017c gene of EU272902

63

protein-level

Hit (GenBank Accn)

Product

Source Genome

Eval.

Ident.(%)

1) Sputw3181_1087
( YP_962491.1 )

N-6 DNA methylase

NC_008750
(Shewanella sp. W3-18-1)

0.0

77

2) PAGR_g3655
( YP_005994364.1 )

N-6 DNA methylase

NC_017554
(Pantoea ananatis PA13)

0.0

77

3) hsdM
( YP_001909235.1 )

type I restriction-modification system, methyltransferase subunit

NC_010694
(Erwinia tasmaniensis Et1/99)

0.0

77

4) amad1_05825
( YP_006976038.1 )

N-6 DNA methylase

NC_019393
(Alteromonas macleodii AltDE1)

0.0

78

5) I636_05840
( YP_008183148.1 )

N-6 DNA methylase

NC_021714
(Alteromonas macleodii Ionian Sea UM4b)

0.0

78

6) I635_05805
( YP_008179094.1 )

N-6 DNA methylase

NC_021713
(Alteromonas macleodii Ionian Sea UM7)

0.0

78

7) MEALZ_3669
( YP_004918910.1 )

N-6 DNA methylase

NC_016112
(Methylomicrobium alcaliphilum 20Z)

0.0

77

8) HDN1F_11600
( YP_003810399.1 )

type I restriction-modification system DNA methylase

NC_014366
(gamma proteobacterium HdN1)

0.0

76

9) hsdM
( YP_005804550.1 )

type I restriction-modification system DNA methylase

NC_017390
(Erwinia pyrifoliae DSM 12163)

0.0

76

10) EpC_35330
( YP_002650514.1 )

DNA methylase

NC_012214
(Erwinia pyrifoliae Ep1/96)

0.0

76

11) Shewmr7_1782
( YP_737832.1 )

N-6 DNA methylase

NC_008322
(Shewanella sp. MR-7)

0.0

76

12) CYCME_2465
( YP_008375129.1 )

Type I restriction-modification system methyltransferase subunit

NC_021917
(Cycloclasticus zancles 7-ME)

0.0

76

13) HP15_1578
( YP_005885270.1 )

type I restriction-modification system, methyltransferase subunit

NC_017506
(Marinobacter adhaerens HP15)

0.0

75

14) Tola_2273
( YP_002893457.1 )

N-6 DNA methylase

NC_012691
(Tolumonas auensis DSM 9187)

0.0

77

15) NT01EI_2505
( YP_002933910.1 )

N-6 DNA Methylase

NC_012779
(Edwardsiella ictaluri 93-146)

0.0

76

16) CGSHiGG_03080
( YP_001291999.1 )

putative type I restriction-modification system, methyltransferase subunit

NC_009567
(Haemophilus influenzae PittGG)

0.0

71

17) hsdM1
( YP_247828.1 )

type I restriction-modification system, methyltransferase subunit

NC_007146
(Haemophilus influenzae 86-028NP)

0.0

71

18) hsdM2
( YP_005827193.1 )

Probable type I restriction modification system, methylase component HsdM2

NC_017451
(Haemophilus influenzae R2866)

0.0

71

19) CGSHiEE_02765
( YP_001290374.1 )

putative type I restriction-modification system, methyltransferase subunit

NC_009566
(Haemophilus influenzae PittEE)

0.0

70

20) hsdM2
( YP_005829021.1 )

type I restriction modification system, methylase component HsdM2

NC_017452
(Haemophilus influenzae R2846)

0.0

70

21) HICON_03790
( YP_004137533.1 )

type I restriction-modification system, methyltransferase subunit

NC_014922
(Haemophilus influenzae F3047)

0.0

71

22) hsdM1
( YP_004134739.1 )

type i restriction-modification system, methyltransferase subunit

NC_014920
(Haemophilus influenzae F3031)

0.0

70

23) Nhal_0751
( YP_003526318.1 )

N-6 DNA methylase

NC_013960
(Nitrosococcus halophilus Nc 4)

0.0

71

24) hsdM
( YP_003189487.1 )

type I DNA methyltransferase M subunit HsdM

NC_013211
(Acetobacter pasteurianus IFO 3283)

0.0

70

25) hsdM
( YP_005479734.1 )

type I DNA methyltransferase M subunit HsdM

NC_017105
(Acetobacter pasteurianus IFO 3283)

0.0

70

26) hsdM
( YP_005485230.1 )

type I DNA methyltransferase M subunit HsdM

NC_017113
(Acetobacter pasteurianus IFO 3283)

0.0

70

27) hsdM
( YP_005485649.1 )

type I DNA methyltransferase M subunit HsdM

NC_017118
(Acetobacter pasteurianus IFO 3283)

0.0

70

28) hsdM
( YP_005488514.1 )

type I DNA methyltransferase M subunit HsdM

NC_017122
(Acetobacter pasteurianus IFO 3283)

0.0

70

29) hsdM
( YP_005491320.1 )

type I DNA methyltransferase M subunit HsdM

NC_017126
(Acetobacter pasteurianus IFO 3283)

0.0

70

30) hsdM
( YP_005491738.1 )

type I DNA methyltransferase M subunit HsdM

NC_017131
(Acetobacter pasteurianus IFO 3283)

0.0

70

31) hsdM
( YP_005500487.1 )

type I DNA methyltransferase M subunit HsdM

NC_017149
(Acetobacter pasteurianus IFO 3283)

0.0

70

32) PSPPH_0107
( YP_272418.1 )

type I restriction-modification system DNA methylase

NC_005773
(Pseudomonas syringae 1448A)

0.0

71

33) Halhy_4893
( YP_004449595.1 )

N-6 DNA methylase

NC_015510
(Haliscomenobacter hydrossis DSM 1100)

0.0

69

34) CHU_2941
( YP_679525.1 )

restriction/modification methyltransferase

NC_008255
(Cytophaga hutchinsonii ATCC 33406)

0.0

68

35) Slin_6258
( YP_003391016.1 )

N-6 DNA methylase

NC_013730
(Spirosoma linguale DSM 74)

0.0

68

36) FBFL15_1800
( YP_004844094.1 )

putative type I modification methyltransferase

NC_016001
(Flavobacterium branchiophilum FL-15)

0.0

68

37) ZPR_4122
( YP_003586622.1 )

DNA methylase HsdM

NC_014041
(Zunongwangia profunda SMA-87)

0.0

66

38) WQG_21370
( YP_007549205.1 )

N-6 DNA methylase

NC_020515
(Bibersteinia trehalosi USDA-ARS-USMARC-192)

0.0

65

39) Fleli_0172
( YP_006432464.1 )

type I restriction-modification system methyltransferase subunit

NC_018018
(Flexibacter litoralis DSM 6794)

0.0

66

40) hsdM
( YP_005324432.1 )

restriction/modification methyltransferase

NC_016940
(Saprospira grandis Lewin)

0.0

67

41) hsdM
( YP_007375977.1 )

putative DNA methylase

NC_020156
(Nonlabens dokdonensis DSW-6)

0.0

64

42) Oscil6304_1854
( YP_007085447.1 )

type I restriction-modification system methyltransferase subunit

NC_019693
(Oscillatoria acuminata PCC 6304)

0.0

60

43) AM1_4786
( YP_001519075.1 )

type I restriction-modification system, M subunit

NC_009925
(Acaryochloris marina MBIC11017)

0.0

61

44) BVU_3413
( YP_001300661.1 )

type I restriction-modification system M subunit

NC_009614
(Bacteroides vulgatus ATCC 8482)

6e-174

49

45) Bacsa_0512
( YP_004257582.1 )

N-6 DNA methylase

NC_015164
(Bacteroides salanitronis DSM 18170)

4e-170

49

46) H681_00040
( YP_007655430.1 )

N-6 DNA methylase

NC_020829
(Pseudomonas denitrificans ATCC 13867)

1e-155

46

47) Ilyop_1055
( YP_003967184.1 )

N-6 DNA methylase

NC_014632
(Ilyobacter polytropus DSM 2926)

7e-154

46

48) Glov_2201
( YP_001952437.1 )

N-6 DNA methylase

NC_010814
(Geobacter lovleyi SZ)

6e-154

46

49) CAP2UW1_4292
( YP_003169457.1 )

N-6 DNA methylase

NC_013194
(Candidatus Accumulibacter phosphatis UW-1)

2e-153

44

50) PSJM300_00040
( YP_006522450.1 )

N-6 DNA methylase

NC_018177
(Pseudomonas stutzeri DSM 10701)

9e-153

46

51) Alide2_2051
( YP_004387942.1 )

N-6 DNA methylase

NC_015422
(Alicycliphilus denitrificans K601)

2e-152

45

52) MCA0278
( YP_112812.1 )

type I restriction-modification system, M subunit

NC_002977
(Methylococcus capsulatus Bath)

7e-152

46

53) PA2735
( NP_251425.1 )

restriction-modification system protein

NC_002516
(Pseudomonas aeruginosa PAO1)

2e-150

45

54) XFLM_04895
( YP_006000305.1 )

N-6 DNA methylase

NC_017562
(Xylella fastidiosa GB514)

3e-147

44

55) XfasM23_2177
( YP_001830846.1 )

N-6 DNA methylase

NC_010577
(Xylella fastidiosa M23)

3e-147

44

56) hsdM
( NP_780246.1 )

type I restriction-modification system DNA methylase

NC_004556
(Xylella fastidiosa Temecula1)

3e-147

44

57) Xfasm12_2269
( YP_001776748.1 )

type I restriction-modification system DNA methylase

NC_010513
(Xylella fastidiosa M12)

7e-140

44

58) Metho_0633
( YP_007312419.1 )

type I restriction-modification system methyltransferase subunit

NC_019977
(Methanomethylovorans hollandica DSM 15978)

9e-135

43

59) GM18_2924
( YP_004199644.1 )

N-6 DNA methylase

NC_014973
(Geobacter sp. M18)

1e-119

48

60) Tery_4473
( YP_723933.1 )

N-6 DNA methylase

NC_008312
(Trichodesmium erythraeum IMS101)

5e-119

51

61) Dd1591_4253
( YP_003006523.1 )

N-6 DNA methylase

NC_012912
(Dickeya zeae Ech1591)

4e-91

44

62) B932_2648
( YP_006985130.1 )

N-6 DNA methylase

NC_019396
(Gluconobacter oxydans H24)

1e-87

42

63) Metme_4216
( YP_004515066.1 )

N-6 DNA methylase

NC_015572
(Methylomonas methanica MC09)

4e-87

42

• Sequence Alignments

1) O3Y_08565 in NC_016944


> EU272902|18|G17|167832524|ACA01834.1|Vibrio_cholerae_Amazonia_3509|-|21794..24175|-|VPI2_0017c|DNA 
methylase HsdM
Length=793

 Score = 1231 bits (4669),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 784/793 (99%), Positives = 791/793 (99%), Gaps = 0/793 (0%)

Query  1    MDHSVHNKLVSFIWSIADDCLRDVYVRGKYRDVILPMVVLRRLDTLLEPSKEAVLEEVRF  60
            MDHSVHNKLVSFIWSIADDCLRDVYVRGKYRDVILPMVVLRRLDTLLEPSKEAVLEEVRF
Sbjct  1    MDHSVHNKLVSFIWSIADDCLRDVYVRGKYRDVILPMVVLRRLDTLLEPSKEAVLEEVRF  60

Query  61   QKEEMNEIELDDAPLCATSGYVFYNTSKWTLQTLFSTATNNQQILLANFEDYLNGFSENV  120
            QKEEMNEIELDDAPLCATSGYVFYNTSKWTLQTLFSTATNNQQILLANFEDYLNGFSENV
Sbjct  61   QKEEMNEIELDDAPLCATSGYVFYNTSKWTLQTLFSTATNNQQILLANFEDYLNGFSENV  120

Query  121  KEIVECFNLKAQIRHMAGKDVLLDVVEKFVSPYINLTPAVKEDPEGNKLPALSNLGMGYV  180
            KEIVECFNLKAQIRHMAGK+VLLDVVEKFVSPYINLTPAVKEDPEGNKLPALSNLGMGYV
Sbjct  121  KEIVECFNLKAQIRHMAGKNVLLDVVEKFVSPYINLTPAVKEDPEGNKLPALSNLGMGYV  180

Query  181  FEELIRKFNEENNEEAGEHFTPREVIELMTHLVFDPIKDNLPLSITVYDPACGSGGMLTE  240
            FEELIRKFNEENNEEAGEHFTPREVIELMTHLVFDPIKDNLPLSITVYDPACGSGGMLTE
Sbjct  181  FEELIRKFNEENNEEAGEHFTPREVIELMTHLVFDPIKDNLPLSITVYDPACGSGGMLTE  240

Query  241  TQNFVEEKYPASNRDIYLYGKEINDETYAICKSDMMIKGNNPENIRVGSTLSTDEFSSNR  300
            TQNFVEEKYPASNRDIYLYGKEINDETYAICKSDMMIKGNNPENIRVGSTLSTDEFSSNR
Sbjct  241  TQNFVEEKYPASNRDIYLYGKEINDETYAICKSDMMIKGNNPENIRVGSTLSTDEFSSNR  300

Query  301  FDFMLSNPPYGKSWASEQKHIKEGKEVVDGRFKVKLKDYWGVESEQEAIPRSSDGQLLFL  360
            FDFMLSNPPYGKSWASEQKHIKEGKEVVDGRFKVKLKDYWGVESEQEAIPRSSDGQLLFL
Sbjct  301  FDFMLSNPPYGKSWASEQKHIKEGKEVVDGRFKVKLKDYWGVESEQEAIPRSSDGQLLFL  360

Query  361  MEMVTKMKSPQDSPLGSRIASVHNGSSLFTGDAGSGESNIRRFIIENDMLDAIVQLPNNL  420
            MEMVTKMKSPQDSPLGSRIASVHNGSSLFTGDAGSGESNIRR+IIENDMLDAIVQLPNNL
Sbjct  361  MEMVTKMKSPQDSPLGSRIASVHNGSSLFTGDAGSGESNIRRYIIENDMLDAIVQLPNNL  420

Query  421  FYNTGITTYIWLLNNNKPENRQGKVQLIDASLLFRKLRKNLGNKNCEFSPEHIAEIVSTY  480
            FYNTGITTYIWLLNNNKPENRQGKVQLIDASLLFRKLRKNLGNKNCEFSPEHIAEIVSTY
Sbjct  421  FYNTGITTYIWLLNNNKPENRQGKVQLIDASLLFRKLRKNLGNKNCEFSPEHIAEIVSTY  480

Query  481  LENQSVERAIDEKGDPVGIAAQVFKNQDFGYYKVNIERPDRRNAQFRADLIEPLRFENSQ  540
            LENQSVERAIDEKGDPVGIAAQVFKNQDFGYYKVNIERPDRRNAQFRADLIEPLRFENSQ
Sbjct  481  LENQSVERAIDEKGDPVGIAAQVFKNQDFGYYKVNIERPDRRNAQFRADLIEPLRFENSQ  540

Query  541  REVMEYLYAEYGEQVYDAGFVKGIEKEITKWCEENDISLNKAAKTKLLDTKNWIKQRTLV  600
            REVMEYLYAEYGEQVYDAGFVKGIEKEITKWCEENDISLNKAAKTKLLDTKNW+KQRTLV
Sbjct  541  REVMEYLYAEYGEQVYDAGFVKGIEKEITKWCEENDISLNKAAKTKLLDTKNWMKQRTLV  600

Query  601  NVASQLHKKIGDEVYNDFNQFKQLVDAELTSLGLKLSAPEKKAILDAVSWYDENAEKVIK  660
            N ASQLHKKIGDEVYNDFNQFKQLVDAELTSLGLKLSAPEKKAILDAVSWYDENAEKVIK
Sbjct  601  NAASQLHKKIGDEVYNDFNQFKQLVDAELTSLGLKLSAPEKKAILDAVSWYDENAEKVIK  660

Query  661  KVAklkqdkldelleNYECELQDLPDFGYYPTGNHNEFVTYESSSDLRDSESVPLEQSIY  720
            KVAKLKQDKLD+LLENYECEL+DLPDFGYYPTGNHNEFVTYESSSDLRDSESVPLEQSIY
Sbjct  661  KVAKLKQDKLDDLLENYECELEDLPDFGYYPTGNHNEFVTYESSSDLRDSESVPLEQSIY  720

Query  721  QYFLDEVKPHVDEAWINLESVKIGYEISFNKYFYRHKPLRSMDEVAGDIIALEQKAEGLI  780
            QYFLDEVKPHVDEAW+NLESVKIGYEISFNKYFYRHKPLRSMDEVA +IIALEQKAEGLI
Sbjct  721  QYFLDEVKPHVDEAWVNLESVKIGYEISFNKYFYRHKPLRSMDEVAKEIIALEQKAEGLI  780

Query  781  ADILGISVAKVQG  793
            ADILGISVAKVQG
Sbjct  781  ADILGISVAKVQG  793

2) VCM66_1707 in NC_012578


> EU272902|18|G17|167832524|ACA01834.1|Vibrio_cholerae_Amazonia_3509|-|21794..24175|-|VPI2_0017c|DNA 
methylase HsdM
Length=793

 Score = 1231 bits (4669),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 784/793 (99%), Positives = 791/793 (99%), Gaps = 0/793 (0%)

Query  1    MDHSVHNKLVSFIWSIADDCLRDVYVRGKYRDVILPMVVLRRLDTLLEPSKEAVLEEVRF  60
            MDHSVHNKLVSFIWSIADDCLRDVYVRGKYRDVILPMVVLRRLDTLLEPSKEAVLEEVRF
Sbjct  1    MDHSVHNKLVSFIWSIADDCLRDVYVRGKYRDVILPMVVLRRLDTLLEPSKEAVLEEVRF  60

Query  61   QKEEMNEIELDDAPLCATSGYVFYNTSKWTLQTLFSTATNNQQILLANFEDYLNGFSENV  120
            QKEEMNEIELDDAPLCATSGYVFYNTSKWTLQTLFSTATNNQQILLANFEDYLNGFSENV
Sbjct  61   QKEEMNEIELDDAPLCATSGYVFYNTSKWTLQTLFSTATNNQQILLANFEDYLNGFSENV  120

Query  121  KEIVECFNLKAQIRHMAGKDVLLDVVEKFVSPYINLTPAVKEDPEGNKLPALSNLGMGYV  180
            KEIVECFNLKAQIRHMAGK+VLLDVVEKFVSPYINLTPAVKEDPEGNKLPALSNLGMGYV
Sbjct  121  KEIVECFNLKAQIRHMAGKNVLLDVVEKFVSPYINLTPAVKEDPEGNKLPALSNLGMGYV  180

Query  181  FEELIRKFNEENNEEAGEHFTPREVIELMTHLVFDPIKDNLPLSITVYDPACGSGGMLTE  240
            FEELIRKFNEENNEEAGEHFTPREVIELMTHLVFDPIKDNLPLSITVYDPACGSGGMLTE
Sbjct  181  FEELIRKFNEENNEEAGEHFTPREVIELMTHLVFDPIKDNLPLSITVYDPACGSGGMLTE  240

Query  241  TQNFVEEKYPASNRDIYLYGKEINDETYAICKSDMMIKGNNPENIRVGSTLSTDEFSSNR  300
            TQNFVEEKYPASNRDIYLYGKEINDETYAICKSDMMIKGNNPENIRVGSTLSTDEFSSNR
Sbjct  241  TQNFVEEKYPASNRDIYLYGKEINDETYAICKSDMMIKGNNPENIRVGSTLSTDEFSSNR  300

Query  301  FDFMLSNPPYGKSWASEQKHIKEGKEVVDGRFKVKLKDYWGVESEQEAIPRSSDGQLLFL  360
            FDFMLSNPPYGKSWASEQKHIKEGKEVVDGRFKVKLKDYWGVESEQEAIPRSSDGQLLFL
Sbjct  301  FDFMLSNPPYGKSWASEQKHIKEGKEVVDGRFKVKLKDYWGVESEQEAIPRSSDGQLLFL  360

Query  361  MEMVTKMKSPQDSPLGSRIASVHNGSSLFTGDAGSGESNIRRFIIENDMLDAIVQLPNNL  420
            MEMVTKMKSPQDSPLGSRIASVHNGSSLFTGDAGSGESNIRR+IIENDMLDAIVQLPNNL
Sbjct  361  MEMVTKMKSPQDSPLGSRIASVHNGSSLFTGDAGSGESNIRRYIIENDMLDAIVQLPNNL  420

Query  421  FYNTGITTYIWLLNNNKPENRQGKVQLIDASLLFRKLRKNLGNKNCEFSPEHIAEIVSTY  480
            FYNTGITTYIWLLNNNKPENRQGKVQLIDASLLFRKLRKNLGNKNCEFSPEHIAEIVSTY
Sbjct  421  FYNTGITTYIWLLNNNKPENRQGKVQLIDASLLFRKLRKNLGNKNCEFSPEHIAEIVSTY  480

Query  481  LENQSVERAIDEKGDPVGIAAQVFKNQDFGYYKVNIERPDRRNAQFRADLIEPLRFENSQ  540
            LENQSVERAIDEKGDPVGIAAQVFKNQDFGYYKVNIERPDRRNAQFRADLIEPLRFENSQ
Sbjct  481  LENQSVERAIDEKGDPVGIAAQVFKNQDFGYYKVNIERPDRRNAQFRADLIEPLRFENSQ  540

Query  541  REVMEYLYAEYGEQVYDAGFVKGIEKEITKWCEENDISLNKAAKTKLLDTKNWIKQRTLV  600
            REVMEYLYAEYGEQVYDAGFVKGIEKEITKWCEENDISLNKAAKTKLLDTKNW+KQRTLV
Sbjct  541  REVMEYLYAEYGEQVYDAGFVKGIEKEITKWCEENDISLNKAAKTKLLDTKNWMKQRTLV  600

Query  601  NVASQLHKKIGDEVYNDFNQFKQLVDAELTSLGLKLSAPEKKAILDAVSWYDENAEKVIK  660
            N ASQLHKKIGDEVYNDFNQFKQLVDAELTSLGLKLSAPEKKAILDAVSWYDENAEKVIK
Sbjct  601  NAASQLHKKIGDEVYNDFNQFKQLVDAELTSLGLKLSAPEKKAILDAVSWYDENAEKVIK  660

Query  661  KVAklkqdkldelleNYECELQDLPDFGYYPTGNHNEFVTYESSSDLRDSESVPLEQSIY  720
            KVAKLKQDKLD+LLENYECEL+DLPDFGYYPTGNHNEFVTYESSSDLRDSESVPLEQSIY
Sbjct  661  KVAKLKQDKLDDLLENYECELEDLPDFGYYPTGNHNEFVTYESSSDLRDSESVPLEQSIY  720

Query  721  QYFLDEVKPHVDEAWINLESVKIGYEISFNKYFYRHKPLRSMDEVAGDIIALEQKAEGLI  780
            QYFLDEVKPHVDEAW+NLESVKIGYEISFNKYFYRHKPLRSMDEVA +IIALEQKAEGLI
Sbjct  721  QYFLDEVKPHVDEAWVNLESVKIGYEISFNKYFYRHKPLRSMDEVAKEIIALEQKAEGLI  780

Query  781  ADILGISVAKVQG  793
            ADILGISVAKVQG
Sbjct  781  ADILGISVAKVQG  793

3) VCD_002601 in NC_012668


> EU272902|18|G17|167832524|ACA01834.1|Vibrio_cholerae_Amazonia_3509|-|21794..24175|-|VPI2_0017c|DNA 
methylase HsdM
Length=793

 Score = 1231 bits (4669),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 784/793 (99%), Positives = 791/793 (99%), Gaps = 0/793 (0%)

Query  1    MDHSVHNKLVSFIWSIADDCLRDVYVRGKYRDVILPMVVLRRLDTLLEPSKEAVLEEVRF  60
            MDHSVHNKLVSFIWSIADDCLRDVYVRGKYRDVILPMVVLRRLDTLLEPSKEAVLEEVRF
Sbjct  1    MDHSVHNKLVSFIWSIADDCLRDVYVRGKYRDVILPMVVLRRLDTLLEPSKEAVLEEVRF  60

Query  61   QKEEMNEIELDDAPLCATSGYVFYNTSKWTLQTLFSTATNNQQILLANFEDYLNGFSENV  120
            QKEEMNEIELDDAPLCATSGYVFYNTSKWTLQTLFSTATNNQQILLANFEDYLNGFSENV
Sbjct  61   QKEEMNEIELDDAPLCATSGYVFYNTSKWTLQTLFSTATNNQQILLANFEDYLNGFSENV  120

Query  121  KEIVECFNLKAQIRHMAGKDVLLDVVEKFVSPYINLTPAVKEDPEGNKLPALSNLGMGYV  180
            KEIVECFNLKAQIRHMAGK+VLLDVVEKFVSPYINLTPAVKEDPEGNKLPALSNLGMGYV
Sbjct  121  KEIVECFNLKAQIRHMAGKNVLLDVVEKFVSPYINLTPAVKEDPEGNKLPALSNLGMGYV  180

Query  181  FEELIRKFNEENNEEAGEHFTPREVIELMTHLVFDPIKDNLPLSITVYDPACGSGGMLTE  240
            FEELIRKFNEENNEEAGEHFTPREVIELMTHLVFDPIKDNLPLSITVYDPACGSGGMLTE
Sbjct  181  FEELIRKFNEENNEEAGEHFTPREVIELMTHLVFDPIKDNLPLSITVYDPACGSGGMLTE  240

Query  241  TQNFVEEKYPASNRDIYLYGKEINDETYAICKSDMMIKGNNPENIRVGSTLSTDEFSSNR  300
            TQNFVEEKYPASNRDIYLYGKEINDETYAICKSDMMIKGNNPENIRVGSTLSTDEFSSNR
Sbjct  241  TQNFVEEKYPASNRDIYLYGKEINDETYAICKSDMMIKGNNPENIRVGSTLSTDEFSSNR  300

Query  301  FDFMLSNPPYGKSWASEQKHIKEGKEVVDGRFKVKLKDYWGVESEQEAIPRSSDGQLLFL  360
            FDFMLSNPPYGKSWASEQKHIKEGKEVVDGRFKVKLKDYWGVESEQEAIPRSSDGQLLFL
Sbjct  301  FDFMLSNPPYGKSWASEQKHIKEGKEVVDGRFKVKLKDYWGVESEQEAIPRSSDGQLLFL  360

Query  361  MEMVTKMKSPQDSPLGSRIASVHNGSSLFTGDAGSGESNIRRFIIENDMLDAIVQLPNNL  420
            MEMVTKMKSPQDSPLGSRIASVHNGSSLFTGDAGSGESNIRR+IIENDMLDAIVQLPNNL
Sbjct  361  MEMVTKMKSPQDSPLGSRIASVHNGSSLFTGDAGSGESNIRRYIIENDMLDAIVQLPNNL  420

Query  421  FYNTGITTYIWLLNNNKPENRQGKVQLIDASLLFRKLRKNLGNKNCEFSPEHIAEIVSTY  480
            FYNTGITTYIWLLNNNKPENRQGKVQLIDASLLFRKLRKNLGNKNCEFSPEHIAEIVSTY
Sbjct  421  FYNTGITTYIWLLNNNKPENRQGKVQLIDASLLFRKLRKNLGNKNCEFSPEHIAEIVSTY  480

Query  481  LENQSVERAIDEKGDPVGIAAQVFKNQDFGYYKVNIERPDRRNAQFRADLIEPLRFENSQ  540
            LENQSVERAIDEKGDPVGIAAQVFKNQDFGYYKVNIERPDRRNAQFRADLIEPLRFENSQ
Sbjct  481  LENQSVERAIDEKGDPVGIAAQVFKNQDFGYYKVNIERPDRRNAQFRADLIEPLRFENSQ  540

Query  541  REVMEYLYAEYGEQVYDAGFVKGIEKEITKWCEENDISLNKAAKTKLLDTKNWIKQRTLV  600
            REVMEYLYAEYGEQVYDAGFVKGIEKEITKWCEENDISLNKAAKTKLLDTKNW+KQRTLV
Sbjct  541  REVMEYLYAEYGEQVYDAGFVKGIEKEITKWCEENDISLNKAAKTKLLDTKNWMKQRTLV  600

Query  601  NVASQLHKKIGDEVYNDFNQFKQLVDAELTSLGLKLSAPEKKAILDAVSWYDENAEKVIK  660
            N ASQLHKKIGDEVYNDFNQFKQLVDAELTSLGLKLSAPEKKAILDAVSWYDENAEKVIK
Sbjct  601  NAASQLHKKIGDEVYNDFNQFKQLVDAELTSLGLKLSAPEKKAILDAVSWYDENAEKVIK  660

Query  661  KVAklkqdkldelleNYECELQDLPDFGYYPTGNHNEFVTYESSSDLRDSESVPLEQSIY  720
            KVAKLKQDKLD+LLENYECEL+DLPDFGYYPTGNHNEFVTYESSSDLRDSESVPLEQSIY
Sbjct  661  KVAKLKQDKLDDLLENYECELEDLPDFGYYPTGNHNEFVTYESSSDLRDSESVPLEQSIY  720

Query  721  QYFLDEVKPHVDEAWINLESVKIGYEISFNKYFYRHKPLRSMDEVAGDIIALEQKAEGLI  780
            QYFLDEVKPHVDEAW+NLESVKIGYEISFNKYFYRHKPLRSMDEVA +IIALEQKAEGLI
Sbjct  721  QYFLDEVKPHVDEAWVNLESVKIGYEISFNKYFYRHKPLRSMDEVAKEIIALEQKAEGLI  780

Query  781  ADILGISVAKVQG  793
            ADILGISVAKVQG
Sbjct  781  ADILGISVAKVQG  793

4) Vch1786_I1263 in NC_016445


> EU272902|18|G17|167832524|ACA01834.1|Vibrio_cholerae_Amazonia_3509|-|21794..24175|-|VPI2_0017c|DNA 
methylase HsdM
Length=793

 Score = 1231 bits (4669),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 784/793 (99%), Positives = 791/793 (99%), Gaps = 0/793 (0%)

Query  1    MDHSVHNKLVSFIWSIADDCLRDVYVRGKYRDVILPMVVLRRLDTLLEPSKEAVLEEVRF  60
            MDHSVHNKLVSFIWSIADDCLRDVYVRGKYRDVILPMVVLRRLDTLLEPSKEAVLEEVRF
Sbjct  1    MDHSVHNKLVSFIWSIADDCLRDVYVRGKYRDVILPMVVLRRLDTLLEPSKEAVLEEVRF  60

Query  61   QKEEMNEIELDDAPLCATSGYVFYNTSKWTLQTLFSTATNNQQILLANFEDYLNGFSENV  120
            QKEEMNEIELDDAPLCATSGYVFYNTSKWTLQTLFSTATNNQQILLANFEDYLNGFSENV
Sbjct  61   QKEEMNEIELDDAPLCATSGYVFYNTSKWTLQTLFSTATNNQQILLANFEDYLNGFSENV  120

Query  121  KEIVECFNLKAQIRHMAGKDVLLDVVEKFVSPYINLTPAVKEDPEGNKLPALSNLGMGYV  180
            KEIVECFNLKAQIRHMAGK+VLLDVVEKFVSPYINLTPAVKEDPEGNKLPALSNLGMGYV
Sbjct  121  KEIVECFNLKAQIRHMAGKNVLLDVVEKFVSPYINLTPAVKEDPEGNKLPALSNLGMGYV  180

Query  181  FEELIRKFNEENNEEAGEHFTPREVIELMTHLVFDPIKDNLPLSITVYDPACGSGGMLTE  240
            FEELIRKFNEENNEEAGEHFTPREVIELMTHLVFDPIKDNLPLSITVYDPACGSGGMLTE
Sbjct  181  FEELIRKFNEENNEEAGEHFTPREVIELMTHLVFDPIKDNLPLSITVYDPACGSGGMLTE  240

Query  241  TQNFVEEKYPASNRDIYLYGKEINDETYAICKSDMMIKGNNPENIRVGSTLSTDEFSSNR  300
            TQNFVEEKYPASNRDIYLYGKEINDETYAICKSDMMIKGNNPENIRVGSTLSTDEFSSNR
Sbjct  241  TQNFVEEKYPASNRDIYLYGKEINDETYAICKSDMMIKGNNPENIRVGSTLSTDEFSSNR  300

Query  301  FDFMLSNPPYGKSWASEQKHIKEGKEVVDGRFKVKLKDYWGVESEQEAIPRSSDGQLLFL  360
            FDFMLSNPPYGKSWASEQKHIKEGKEVVDGRFKVKLKDYWGVESEQEAIPRSSDGQLLFL
Sbjct  301  FDFMLSNPPYGKSWASEQKHIKEGKEVVDGRFKVKLKDYWGVESEQEAIPRSSDGQLLFL  360

Query  361  MEMVTKMKSPQDSPLGSRIASVHNGSSLFTGDAGSGESNIRRFIIENDMLDAIVQLPNNL  420
            MEMVTKMKSPQDSPLGSRIASVHNGSSLFTGDAGSGESNIRR+IIENDMLDAIVQLPNNL
Sbjct  361  MEMVTKMKSPQDSPLGSRIASVHNGSSLFTGDAGSGESNIRRYIIENDMLDAIVQLPNNL  420

Query  421  FYNTGITTYIWLLNNNKPENRQGKVQLIDASLLFRKLRKNLGNKNCEFSPEHIAEIVSTY  480
            FYNTGITTYIWLLNNNKPENRQGKVQLIDASLLFRKLRKNLGNKNCEFSPEHIAEIVSTY
Sbjct  421  FYNTGITTYIWLLNNNKPENRQGKVQLIDASLLFRKLRKNLGNKNCEFSPEHIAEIVSTY  480

Query  481  LENQSVERAIDEKGDPVGIAAQVFKNQDFGYYKVNIERPDRRNAQFRADLIEPLRFENSQ  540
            LENQSVERAIDEKGDPVGIAAQVFKNQDFGYYKVNIERPDRRNAQFRADLIEPLRFENSQ
Sbjct  481  LENQSVERAIDEKGDPVGIAAQVFKNQDFGYYKVNIERPDRRNAQFRADLIEPLRFENSQ  540

Query  541  REVMEYLYAEYGEQVYDAGFVKGIEKEITKWCEENDISLNKAAKTKLLDTKNWIKQRTLV  600
            REVMEYLYAEYGEQVYDAGFVKGIEKEITKWCEENDISLNKAAKTKLLDTKNW+KQRTLV
Sbjct  541  REVMEYLYAEYGEQVYDAGFVKGIEKEITKWCEENDISLNKAAKTKLLDTKNWMKQRTLV  600

Query  601  NVASQLHKKIGDEVYNDFNQFKQLVDAELTSLGLKLSAPEKKAILDAVSWYDENAEKVIK  660
            N ASQLHKKIGDEVYNDFNQFKQLVDAELTSLGLKLSAPEKKAILDAVSWYDENAEKVIK
Sbjct  601  NAASQLHKKIGDEVYNDFNQFKQLVDAELTSLGLKLSAPEKKAILDAVSWYDENAEKVIK  660

Query  661  KVAklkqdkldelleNYECELQDLPDFGYYPTGNHNEFVTYESSSDLRDSESVPLEQSIY  720
            KVAKLKQDKLD+LLENYECEL+DLPDFGYYPTGNHNEFVTYESSSDLRDSESVPLEQSIY
Sbjct  661  KVAKLKQDKLDDLLENYECELEDLPDFGYYPTGNHNEFVTYESSSDLRDSESVPLEQSIY  720

Query  721  QYFLDEVKPHVDEAWINLESVKIGYEISFNKYFYRHKPLRSMDEVAGDIIALEQKAEGLI  780
            QYFLDEVKPHVDEAW+NLESVKIGYEISFNKYFYRHKPLRSMDEVA +IIALEQKAEGLI
Sbjct  721  QYFLDEVKPHVDEAWVNLESVKIGYEISFNKYFYRHKPLRSMDEVAKEIIALEQKAEGLI  780

Query  781  ADILGISVAKVQG  793
            ADILGISVAKVQG
Sbjct  781  ADILGISVAKVQG  793

5) VC1769 in NC_002505


> EU272902|18|G17|167832524|ACA01834.1|Vibrio_cholerae_Amazonia_3509|-|21794..24175|-|VPI2_0017c|DNA 
methylase HsdM
Length=793

 Score = 1231 bits (4669),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 784/793 (99%), Positives = 791/793 (99%), Gaps = 0/793 (0%)

Query  1    MDHSVHNKLVSFIWSIADDCLRDVYVRGKYRDVILPMVVLRRLDTLLEPSKEAVLEEVRF  60
            MDHSVHNKLVSFIWSIADDCLRDVYVRGKYRDVILPMVVLRRLDTLLEPSKEAVLEEVRF
Sbjct  1    MDHSVHNKLVSFIWSIADDCLRDVYVRGKYRDVILPMVVLRRLDTLLEPSKEAVLEEVRF  60

Query  61   QKEEMNEIELDDAPLCATSGYVFYNTSKWTLQTLFSTATNNQQILLANFEDYLNGFSENV  120
            QKEEMNEIELDDAPLCATSGYVFYNTSKWTLQTLFSTATNNQQILLANFEDYLNGFSENV
Sbjct  61   QKEEMNEIELDDAPLCATSGYVFYNTSKWTLQTLFSTATNNQQILLANFEDYLNGFSENV  120

Query  121  KEIVECFNLKAQIRHMAGKDVLLDVVEKFVSPYINLTPAVKEDPEGNKLPALSNLGMGYV  180
            KEIVECFNLKAQIRHMAGK+VLLDVVEKFVSPYINLTPAVKEDPEGNKLPALSNLGMGYV
Sbjct  121  KEIVECFNLKAQIRHMAGKNVLLDVVEKFVSPYINLTPAVKEDPEGNKLPALSNLGMGYV  180

Query  181  FEELIRKFNEENNEEAGEHFTPREVIELMTHLVFDPIKDNLPLSITVYDPACGSGGMLTE  240
            FEELIRKFNEENNEEAGEHFTPREVIELMTHLVFDPIKDNLPLSITVYDPACGSGGMLTE
Sbjct  181  FEELIRKFNEENNEEAGEHFTPREVIELMTHLVFDPIKDNLPLSITVYDPACGSGGMLTE  240

Query  241  TQNFVEEKYPASNRDIYLYGKEINDETYAICKSDMMIKGNNPENIRVGSTLSTDEFSSNR  300
            TQNFVEEKYPASNRDIYLYGKEINDETYAICKSDMMIKGNNPENIRVGSTLSTDEFSSNR
Sbjct  241  TQNFVEEKYPASNRDIYLYGKEINDETYAICKSDMMIKGNNPENIRVGSTLSTDEFSSNR  300

Query  301  FDFMLSNPPYGKSWASEQKHIKEGKEVVDGRFKVKLKDYWGVESEQEAIPRSSDGQLLFL  360
            FDFMLSNPPYGKSWASEQKHIKEGKEVVDGRFKVKLKDYWGVESEQEAIPRSSDGQLLFL
Sbjct  301  FDFMLSNPPYGKSWASEQKHIKEGKEVVDGRFKVKLKDYWGVESEQEAIPRSSDGQLLFL  360

Query  361  MEMVTKMKSPQDSPLGSRIASVHNGSSLFTGDAGSGESNIRRFIIENDMLDAIVQLPNNL  420
            MEMVTKMKSPQDSPLGSRIASVHNGSSLFTGDAGSGESNIRR+IIENDMLDAIVQLPNNL
Sbjct  361  MEMVTKMKSPQDSPLGSRIASVHNGSSLFTGDAGSGESNIRRYIIENDMLDAIVQLPNNL  420

Query  421  FYNTGITTYIWLLNNNKPENRQGKVQLIDASLLFRKLRKNLGNKNCEFSPEHIAEIVSTY  480
            FYNTGITTYIWLLNNNKPENRQGKVQLIDASLLFRKLRKNLGNKNCEFSPEHIAEIVSTY
Sbjct  421  FYNTGITTYIWLLNNNKPENRQGKVQLIDASLLFRKLRKNLGNKNCEFSPEHIAEIVSTY  480

Query  481  LENQSVERAIDEKGDPVGIAAQVFKNQDFGYYKVNIERPDRRNAQFRADLIEPLRFENSQ  540
            LENQSVERAIDEKGDPVGIAAQVFKNQDFGYYKVNIERPDRRNAQFRADLIEPLRFENSQ
Sbjct  481  LENQSVERAIDEKGDPVGIAAQVFKNQDFGYYKVNIERPDRRNAQFRADLIEPLRFENSQ  540

Query  541  REVMEYLYAEYGEQVYDAGFVKGIEKEITKWCEENDISLNKAAKTKLLDTKNWIKQRTLV  600
            REVMEYLYAEYGEQVYDAGFVKGIEKEITKWCEENDISLNKAAKTKLLDTKNW+KQRTLV
Sbjct  541  REVMEYLYAEYGEQVYDAGFVKGIEKEITKWCEENDISLNKAAKTKLLDTKNWMKQRTLV  600

Query  601  NVASQLHKKIGDEVYNDFNQFKQLVDAELTSLGLKLSAPEKKAILDAVSWYDENAEKVIK  660
            N ASQLHKKIGDEVYNDFNQFKQLVDAELTSLGLKLSAPEKKAILDAVSWYDENAEKVIK
Sbjct  601  NAASQLHKKIGDEVYNDFNQFKQLVDAELTSLGLKLSAPEKKAILDAVSWYDENAEKVIK  660

Query  661  KVAklkqdkldelleNYECELQDLPDFGYYPTGNHNEFVTYESSSDLRDSESVPLEQSIY  720
            KVAKLKQDKLD+LLENYECEL+DLPDFGYYPTGNHNEFVTYESSSDLRDSESVPLEQSIY
Sbjct  661  KVAKLKQDKLDDLLENYECELEDLPDFGYYPTGNHNEFVTYESSSDLRDSESVPLEQSIY  720

Query  721  QYFLDEVKPHVDEAWINLESVKIGYEISFNKYFYRHKPLRSMDEVAGDIIALEQKAEGLI  780
            QYFLDEVKPHVDEAW+NLESVKIGYEISFNKYFYRHKPLRSMDEVA +IIALEQKAEGLI
Sbjct  721  QYFLDEVKPHVDEAWVNLESVKIGYEISFNKYFYRHKPLRSMDEVAKEIIALEQKAEGLI  780

Query  781  ADILGISVAKVQG  793
            ADILGISVAKVQG
Sbjct  781  ADILGISVAKVQG  793

6) VC395_1883 in NC_012582


> EU272902|18|G17|167832524|ACA01834.1|Vibrio_cholerae_Amazonia_3509|-|21794..24175|-|VPI2_0017c|DNA 
methylase HsdM
Length=793

 Score = 1231 bits (4669),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 784/793 (99%), Positives = 791/793 (99%), Gaps = 0/793 (0%)

Query  1    MDHSVHNKLVSFIWSIADDCLRDVYVRGKYRDVILPMVVLRRLDTLLEPSKEAVLEEVRF  60
            MDHSVHNKLVSFIWSIADDCLRDVYVRGKYRDVILPMVVLRRLDTLLEPSKEAVLEEVRF
Sbjct  1    MDHSVHNKLVSFIWSIADDCLRDVYVRGKYRDVILPMVVLRRLDTLLEPSKEAVLEEVRF  60

Query  61   QKEEMNEIELDDAPLCATSGYVFYNTSKWTLQTLFSTATNNQQILLANFEDYLNGFSENV  120
            QKEEMNEIELDDAPLCATSGYVFYNTSKWTLQTLFSTATNNQQILLANFEDYLNGFSENV
Sbjct  61   QKEEMNEIELDDAPLCATSGYVFYNTSKWTLQTLFSTATNNQQILLANFEDYLNGFSENV  120

Query  121  KEIVECFNLKAQIRHMAGKDVLLDVVEKFVSPYINLTPAVKEDPEGNKLPALSNLGMGYV  180
            KEIVECFNLKAQIRHMAGK+VLLDVVEKFVSPYINLTPAVKEDPEGNKLPALSNLGMGYV
Sbjct  121  KEIVECFNLKAQIRHMAGKNVLLDVVEKFVSPYINLTPAVKEDPEGNKLPALSNLGMGYV  180

Query  181  FEELIRKFNEENNEEAGEHFTPREVIELMTHLVFDPIKDNLPLSITVYDPACGSGGMLTE  240
            FEELIRKFNEENNEEAGEHFTPREVIELMTHLVFDPIKDNLPLSITVYDPACGSGGMLTE
Sbjct  181  FEELIRKFNEENNEEAGEHFTPREVIELMTHLVFDPIKDNLPLSITVYDPACGSGGMLTE  240

Query  241  TQNFVEEKYPASNRDIYLYGKEINDETYAICKSDMMIKGNNPENIRVGSTLSTDEFSSNR  300
            TQNFVEEKYPASNRDIYLYGKEINDETYAICKSDMMIKGNNPENIRVGSTLSTDEFSSNR
Sbjct  241  TQNFVEEKYPASNRDIYLYGKEINDETYAICKSDMMIKGNNPENIRVGSTLSTDEFSSNR  300

Query  301  FDFMLSNPPYGKSWASEQKHIKEGKEVVDGRFKVKLKDYWGVESEQEAIPRSSDGQLLFL  360
            FDFMLSNPPYGKSWASEQKHIKEGKEVVDGRFKVKLKDYWGVESEQEAIPRSSDGQLLFL
Sbjct  301  FDFMLSNPPYGKSWASEQKHIKEGKEVVDGRFKVKLKDYWGVESEQEAIPRSSDGQLLFL  360

Query  361  MEMVTKMKSPQDSPLGSRIASVHNGSSLFTGDAGSGESNIRRFIIENDMLDAIVQLPNNL  420
            MEMVTKMKSPQDSPLGSRIASVHNGSSLFTGDAGSGESNIRR+IIENDMLDAIVQLPNNL
Sbjct  361  MEMVTKMKSPQDSPLGSRIASVHNGSSLFTGDAGSGESNIRRYIIENDMLDAIVQLPNNL  420

Query  421  FYNTGITTYIWLLNNNKPENRQGKVQLIDASLLFRKLRKNLGNKNCEFSPEHIAEIVSTY  480
            FYNTGITTYIWLLNNNKPENRQGKVQLIDASLLFRKLRKNLGNKNCEFSPEHIAEIVSTY
Sbjct  421  FYNTGITTYIWLLNNNKPENRQGKVQLIDASLLFRKLRKNLGNKNCEFSPEHIAEIVSTY  480

Query  481  LENQSVERAIDEKGDPVGIAAQVFKNQDFGYYKVNIERPDRRNAQFRADLIEPLRFENSQ  540
            LENQSVERAIDEKGDPVGIAAQVFKNQDFGYYKVNIERPDRRNAQFRADLIEPLRFENSQ
Sbjct  481  LENQSVERAIDEKGDPVGIAAQVFKNQDFGYYKVNIERPDRRNAQFRADLIEPLRFENSQ  540

Query  541  REVMEYLYAEYGEQVYDAGFVKGIEKEITKWCEENDISLNKAAKTKLLDTKNWIKQRTLV  600
            REVMEYLYAEYGEQVYDAGFVKGIEKEITKWCEENDISLNKAAKTKLLDTKNW+KQRTLV
Sbjct  541  REVMEYLYAEYGEQVYDAGFVKGIEKEITKWCEENDISLNKAAKTKLLDTKNWMKQRTLV  600

Query  601  NVASQLHKKIGDEVYNDFNQFKQLVDAELTSLGLKLSAPEKKAILDAVSWYDENAEKVIK  660
            N ASQLHKKIGDEVYNDFNQFKQLVDAELTSLGLKLSAPEKKAILDAVSWYDENAEKVIK
Sbjct  601  NAASQLHKKIGDEVYNDFNQFKQLVDAELTSLGLKLSAPEKKAILDAVSWYDENAEKVIK  660

Query  661  KVAklkqdkldelleNYECELQDLPDFGYYPTGNHNEFVTYESSSDLRDSESVPLEQSIY  720
            KVAKLKQDKLD+LLENYECEL+DLPDFGYYPTGNHNEFVTYESSSDLRDSESVPLEQSIY
Sbjct  661  KVAKLKQDKLDDLLENYECELEDLPDFGYYPTGNHNEFVTYESSSDLRDSESVPLEQSIY  720

Query  721  QYFLDEVKPHVDEAWINLESVKIGYEISFNKYFYRHKPLRSMDEVAGDIIALEQKAEGLI  780
            QYFLDEVKPHVDEAW+NLESVKIGYEISFNKYFYRHKPLRSMDEVA +IIALEQKAEGLI
Sbjct  721  QYFLDEVKPHVDEAWVNLESVKIGYEISFNKYFYRHKPLRSMDEVAKEIIALEQKAEGLI  780

Query  781  ADILGISVAKVQG  793
            ADILGISVAKVQG
Sbjct  781  ADILGISVAKVQG  793

7) VC0395_A1367 in NC_009457


> EU272902|18|G17|167832524|ACA01834.1|Vibrio_cholerae_Amazonia_3509|-|21794..24175|-|VPI2_0017c|DNA 
methylase HsdM
Length=793

 Score = 1231 bits (4669),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 784/793 (99%), Positives = 791/793 (99%), Gaps = 0/793 (0%)

Query  1    MDHSVHNKLVSFIWSIADDCLRDVYVRGKYRDVILPMVVLRRLDTLLEPSKEAVLEEVRF  60
            MDHSVHNKLVSFIWSIADDCLRDVYVRGKYRDVILPMVVLRRLDTLLEPSKEAVLEEVRF
Sbjct  1    MDHSVHNKLVSFIWSIADDCLRDVYVRGKYRDVILPMVVLRRLDTLLEPSKEAVLEEVRF  60

Query  61   QKEEMNEIELDDAPLCATSGYVFYNTSKWTLQTLFSTATNNQQILLANFEDYLNGFSENV  120
            QKEEMNEIELDDAPLCATSGYVFYNTSKWTLQTLFSTATNNQQILLANFEDYLNGFSENV
Sbjct  61   QKEEMNEIELDDAPLCATSGYVFYNTSKWTLQTLFSTATNNQQILLANFEDYLNGFSENV  120

Query  121  KEIVECFNLKAQIRHMAGKDVLLDVVEKFVSPYINLTPAVKEDPEGNKLPALSNLGMGYV  180
            KEIVECFNLKAQIRHMAGK+VLLDVVEKFVSPYINLTPAVKEDPEGNKLPALSNLGMGYV
Sbjct  121  KEIVECFNLKAQIRHMAGKNVLLDVVEKFVSPYINLTPAVKEDPEGNKLPALSNLGMGYV  180

Query  181  FEELIRKFNEENNEEAGEHFTPREVIELMTHLVFDPIKDNLPLSITVYDPACGSGGMLTE  240
            FEELIRKFNEENNEEAGEHFTPREVIELMTHLVFDPIKDNLPLSITVYDPACGSGGMLTE
Sbjct  181  FEELIRKFNEENNEEAGEHFTPREVIELMTHLVFDPIKDNLPLSITVYDPACGSGGMLTE  240

Query  241  TQNFVEEKYPASNRDIYLYGKEINDETYAICKSDMMIKGNNPENIRVGSTLSTDEFSSNR  300
            TQNFVEEKYPASNRDIYLYGKEINDETYAICKSDMMIKGNNPENIRVGSTLSTDEFSSNR
Sbjct  241  TQNFVEEKYPASNRDIYLYGKEINDETYAICKSDMMIKGNNPENIRVGSTLSTDEFSSNR  300

Query  301  FDFMLSNPPYGKSWASEQKHIKEGKEVVDGRFKVKLKDYWGVESEQEAIPRSSDGQLLFL  360
            FDFMLSNPPYGKSWASEQKHIKEGKEVVDGRFKVKLKDYWGVESEQEAIPRSSDGQLLFL
Sbjct  301  FDFMLSNPPYGKSWASEQKHIKEGKEVVDGRFKVKLKDYWGVESEQEAIPRSSDGQLLFL  360

Query  361  MEMVTKMKSPQDSPLGSRIASVHNGSSLFTGDAGSGESNIRRFIIENDMLDAIVQLPNNL  420
            MEMVTKMKSPQDSPLGSRIASVHNGSSLFTGDAGSGESNIRR+IIENDMLDAIVQLPNNL
Sbjct  361  MEMVTKMKSPQDSPLGSRIASVHNGSSLFTGDAGSGESNIRRYIIENDMLDAIVQLPNNL  420

Query  421  FYNTGITTYIWLLNNNKPENRQGKVQLIDASLLFRKLRKNLGNKNCEFSPEHIAEIVSTY  480
            FYNTGITTYIWLLNNNKPENRQGKVQLIDASLLFRKLRKNLGNKNCEFSPEHIAEIVSTY
Sbjct  421  FYNTGITTYIWLLNNNKPENRQGKVQLIDASLLFRKLRKNLGNKNCEFSPEHIAEIVSTY  480

Query  481  LENQSVERAIDEKGDPVGIAAQVFKNQDFGYYKVNIERPDRRNAQFRADLIEPLRFENSQ  540
            LENQSVERAIDEKGDPVGIAAQVFKNQDFGYYKVNIERPDRRNAQFRADLIEPLRFENSQ
Sbjct  481  LENQSVERAIDEKGDPVGIAAQVFKNQDFGYYKVNIERPDRRNAQFRADLIEPLRFENSQ  540

Query  541  REVMEYLYAEYGEQVYDAGFVKGIEKEITKWCEENDISLNKAAKTKLLDTKNWIKQRTLV  600
            REVMEYLYAEYGEQVYDAGFVKGIEKEITKWCEENDISLNKAAKTKLLDTKNW+KQRTLV
Sbjct  541  REVMEYLYAEYGEQVYDAGFVKGIEKEITKWCEENDISLNKAAKTKLLDTKNWMKQRTLV  600

Query  601  NVASQLHKKIGDEVYNDFNQFKQLVDAELTSLGLKLSAPEKKAILDAVSWYDENAEKVIK  660
            N ASQLHKKIGDEVYNDFNQFKQLVDAELTSLGLKLSAPEKKAILDAVSWYDENAEKVIK
Sbjct  601  NAASQLHKKIGDEVYNDFNQFKQLVDAELTSLGLKLSAPEKKAILDAVSWYDENAEKVIK  660

Query  661  KVAklkqdkldelleNYECELQDLPDFGYYPTGNHNEFVTYESSSDLRDSESVPLEQSIY  720
            KVAKLKQDKLD+LLENYECEL+DLPDFGYYPTGNHNEFVTYESSSDLRDSESVPLEQSIY
Sbjct  661  KVAKLKQDKLDDLLENYECELEDLPDFGYYPTGNHNEFVTYESSSDLRDSESVPLEQSIY  720

Query  721  QYFLDEVKPHVDEAWINLESVKIGYEISFNKYFYRHKPLRSMDEVAGDIIALEQKAEGLI  780
            QYFLDEVKPHVDEAW+NLESVKIGYEISFNKYFYRHKPLRSMDEVA +IIALEQKAEGLI
Sbjct  721  QYFLDEVKPHVDEAWVNLESVKIGYEISFNKYFYRHKPLRSMDEVAKEIIALEQKAEGLI  780

Query  781  ADILGISVAKVQG  793
            ADILGISVAKVQG
Sbjct  781  ADILGISVAKVQG  793

8) VEA_003234 in NC_013456


> EU272902|18|G17|167832524|ACA01834.1|Vibrio_cholerae_Amazonia_3509|-|21794..24175|-|VPI2_0017c|DNA 
methylase HsdM
Length=793

 Score = 1202 bits (4561),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 751/793 (95%), Positives = 781/793 (99%), Gaps = 0/793 (0%)

Query  1    MDHSVHNKLISFIWSIADDCLRDVYVRGKYRDVILPMVVLRRLDTLLEPSKEAVLEEVRF  60
            MDHSVHNKL+SFIWSIADDCLRDVYVRGKYRDVILPMVVLRRLDTLLEPSKEAVLEEVRF
Sbjct  1    MDHSVHNKLVSFIWSIADDCLRDVYVRGKYRDVILPMVVLRRLDTLLEPSKEAVLEEVRF  60

Query  61   QKEEMNETELDDAPLCAASGYVFYNTSKWTLQTLFSTATNNQQILLANFEDYLNGFSDNV  120
            QKEEMNE ELDDAPLCA+SGYVFYNTSKWTLQTLFSTATNNQQILLANFEDYLNGFS+NV
Sbjct  61   QKEEMNEIELDDAPLCATSGYVFYNTSKWTLQTLFSTATNNQQILLANFEDYLNGFSENV  120

Query  121  KEIVECFNLKAQIRHMAGKDVLLDVVEKFVSPYINLTPTVKEDPEGNKLPALSNLGMGYV  180
            KEIVECFNLKAQIRHMAGK+VLLDVVEKFVSPYINLTP+VKEDPEGNKLPALSNLGMGYV
Sbjct  121  KEIVECFNLKAQIRHMAGKNVLLDVVEKFVSPYINLTPAVKEDPEGNKLPALSNLGMGYV  180

Query  181  FEELIRKFNEENNEEAGEHFTPREVIELMTHLVFDPIKDELPLSITVYDPACGSGGMLTE  240
            FEELIRKFNEENNEEAGEHFTPREVIELMTHLVFDPIKD+LPLSITVYDPACGSGGMLTE
Sbjct  181  FEELIRKFNEENNEEAGEHFTPREVIELMTHLVFDPIKDNLPLSITVYDPACGSGGMLTE  240

Query  241  TQNFVEEKYPASNRDIYLYGKEINDETYAICKSDMMIKGNNPQNIRVGSTLSTDEFSSER  300
            TQNFVEEKYPASNRDIYLYGKEINDETYAICKSDMMIKGNNP+NIRVGSTLSTDEFSS+R
Sbjct  241  TQNFVEEKYPASNRDIYLYGKEINDETYAICKSDMMIKGNNPENIRVGSTLSTDEFSSNR  300

Query  301  FDFMLSNPPYGKSWASEQKHIKDGKDVVDGRFKVKLKDYWGVESEQDAIPRSSDGQLLFL  360
            FDFMLSNPPYGKSWASEQKHIK+GK+VVDGRFKVKLKDYWGVESEQ+AIPRSSDGQLLFL
Sbjct  301  FDFMLSNPPYGKSWASEQKHIKEGKEVVDGRFKVKLKDYWGVESEQEAIPRSSDGQLLFL  360

Query  361  MEMVTKMKSPQVSPLGSRIASVHNGSSLFTGDAGSGESNIRRFIIENDMLDAIVQLPNNL  420
            MEMVTKMKSPQ SPLGSRIASVHNGSSLFTGDAGSGESNIRR+IIENDMLDAIVQLPNNL
Sbjct  361  MEMVTKMKSPQDSPLGSRIASVHNGSSLFTGDAGSGESNIRRYIIENDMLDAIVQLPNNL  420

Query  421  FYNTGITTYIWLLNNNKPESRQGKVQLIDASLLFRKLRKNLGNKNCEFSPEHIAKIVSTY  480
            FYNTGITTYIWLLNNNKPE+RQGKVQLIDASLLFRKLRKNLGNKNCEFSPEHIA IVSTY
Sbjct  421  FYNTGITTYIWLLNNNKPENRQGKVQLIDASLLFRKLRKNLGNKNCEFSPEHIAEIVSTY  480

Query  481  LDNKSVERAIDEKGDSVGIAAQVFKNQDFGYYKVNIERPDRRNAQFRSDLIEPLRFEKSL  540
            L+N+SVERAIDEKGD+VGIAAQVFKNQDFGYYKVNIERPDRRNAQFR+DLIEPLRFE+S 
Sbjct  481  LENQSVERAIDEKGDPVGIAAQVFKNQDFGYYKVNIERPDRRNAQFRADLIEPLRFENSQ  540

Query  541  REVMEYLYVEYGEKVYDAGFVKGVEKEITKWCEENDISLNKAAKTKLLDTKNWIKQRTLV  600
            REVMEYLY EYGE+VYDAGFVKG+EKEITKWCEENDISLNKAAKTKLLDTKNW+KQRTLV
Sbjct  541  REVMEYLYAEYGEQVYDAGFVKGIEKEITKWCEENDISLNKAAKTKLLDTKNWMKQRTLV  600

Query  601  NAASQLHSKIGDEVYNDFNQFKQLVDAELKSLGLKLAATEKKAILDAVSWYNENAEKVIK  660
            NAASQLH KIGDEVYNDFNQFKQLVDAEL SLGLKL+A EKKAILDAVSWY+ENAEKVIK
Sbjct  601  NAASQLHKKIGDEVYNDFNQFKQLVDAELTSLGLKLSAPEKKAILDAVSWYDENAEKVIK  660

Query  661  KVAklkqdkldelleSYECELQDLPDFGYYPTGNHNEFVTYESSSDLRDSESVPLEQSIY  720
            KVAKLKQDKLD+LLE+YECEL+DLPDFGYYPTGNHNEFVTYESSSDLRDSESVPLEQSIY
Sbjct  661  KVAKLKQDKLDDLLENYECELEDLPDFGYYPTGNHNEFVTYESSSDLRDSESVPLEQSIY  720

Query  721  QYFLDEVKPHVDEAWVNLESVKIGYEISFNKYFYRHKPLRSMDEVAKDIIALEQKAEGLI  780
            QYFLDEVKPHVDEAWVNLESVKIGYEISFNKYFYRHKPLRSMDEVAK+IIALEQKAEGLI
Sbjct  721  QYFLDEVKPHVDEAWVNLESVKIGYEISFNKYFYRHKPLRSMDEVAKEIIALEQKAEGLI  780

Query  781  SDILGGDVVKGDA  793
            +DILG  V K ++
Sbjct  781  ADILGISVAKVQG  793

9) Sputw3181_1087 in NC_008750


> EU272902|18|G17|167832524|ACA01834.1|Vibrio_cholerae_Amazonia_3509|-|21794..24175|-|VPI2_0017c|DNA 
methylase HsdM
Length=793

 Score = 1054 bits (3995),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 620/807 (77%), Positives = 711/807 (89%), Gaps = 14/807 (1%)

Query  1    MDHSVHNKLISFIWNIADDCLRDVYVRGKYRDVILPMVVLRRLDTLLEPTKEAVLEEVKF  60
            MDHSVHNKL+SFIW+IADDCLRDVYVRGKYRDVILPMVVLRRLDTLLEP+KEAVLEEV+F
Sbjct  1    MDHSVHNKLVSFIWSIADDCLRDVYVRGKYRDVILPMVVLRRLDTLLEPSKEAVLEEVRF  60

Query  61   QKEEMQATELDDEPLKAASGYVFYNTSKWTLKSLFNTATNNQQILLANFEEYLLGFSDNV  120
            QKEEM+  ELDD PL A+SGYVFYNTSKWTL++LF+TATNNQQILLANFE+YL GFS+NV
Sbjct  61   QKEEMNEIELDDAPLCATSGYVFYNTSKWTLQTLFSTATNNQQILLANFEDYLNGFSENV  120

Query  121  KEIIECFNLKSQIRHMASKQVLLDVVEKFVSPYINLTHETVEDPDGNKMPALTNLGMGYV  180
            KEI+ECFNLK+QIRHMA+K+VLLDVVEKFVSPYINLT    EDP+GNK+PAL+NLGMGYV
Sbjct  121  KEIVECFNLKAQIRHMAGKNVLLDVVEKFVSPYINLTPAVKEDPEGNKLPALSNLGMGYV  180

Query  181  FEELIRKFNEENNEEAGEHFTPREVIELMTHLVFDPVKDQLPLTMTVYDPACGSGGMLTE  240
            FEELIRKFNEENNEEAGEHFTPREVIELMTHLVFDP+KD+LPL++TVYDPACGSGGMLTE
Sbjct  181  FEELIRKFNEENNEEAGEHFTPREVIELMTHLVFDPIKDNLPLSITVYDPACGSGGMLTE  240

Query  241  SQNFIEEKYPNDSRDVYLYGKEINDETYAICKSDMMIKGNNPENIKVGSTLSTDEFAASR  300
            +QNF+EEKYP  +RD+YLYGKEINDETYAICKSDMMIKGNNPENI+VGSTLSTDEF+++R
Sbjct  241  TQNFVEEKYPASNRDIYLYGKEINDETYAICKSDMMIKGNNPENIRVGSTLSTDEFSSNR  300

Query  301  FDFMLSNPPYGKSWASEQKHIKDGSDVIDPRFKVSLKDYWGNLEVVDATPRSSDGQLLFL  360
            FDFMLSNPPYGKSWASEQKHIK+G +V+D RFKV LKDYWG     +A PRSSDGQLLFL
Sbjct  301  FDFMLSNPPYGKSWASEQKHIKEGKEVVDGRFKVKLKDYWGVESEQEAIPRSSDGQLLFL  360

Query  361  MEMVNKMKDPSVSPLGSRIASVHNGSSLFTGDAGGGESNIRRFIIENDMLDAIVQLPNNL  420
            MEMV KMK P  SPLGSRIASVHNGSSLFTGDAG+GESNIRR+IIENDMLDAIVQLPNNL
Sbjct  361  MEMVTKMKSPQDSPLGSRIASVHNGSSLFTGDAGSGESNIRRYIIENDMLDAIVQLPNNL  420

Query  421  FYNTGITTYIWVLNNNKPEARKGKVQLIDASLLYRKLRKNLGNKNCEFAPAHITEITDTY  480
            FYNTGITTYIW+LNNNKPE R+GKVQLIDASLL+RKLRKNLGNKNCEF+P HI+EI  TY
Sbjct  421  FYNTGITTYIWLLNNNKPENRQGKVQLIDASLLFRKLRKNLGNKNCEFSPEHIAEIVSTY  480

Query  481  LACVGVERALDANNDPVGIASKVFSNDDFGYYKVTIERPDRRRAKFTQDAIAPLRFDKQL  540
            L   +VERA+D + DPVGIA++VF N+DFGYYKV IERPDRR A+F  D I PLRF++  
Sbjct  481  LENQSVERAIDEKGDPVGIAAQVFKNQDFGYYKVNIERPDRRNAQFRADLIEPLRFENSQ  540

Query  541  SEVMEYVYAEHGERVYEKTGYGTEKKKSFLKSIEKDILSWCEDNDISLNAKAKAKLLDVK  600
             EVMEY+YAE GE+VY+          +F+K+IEK+I  WCE+NDISLN  AK+KLLD K
Sbjct  541  REVMEYLYAEYGEQVYD---------AGFVKGIEKEITKWCEENDISLNKAAKTKLLDTK  591

Query  601  HWlalkalletaetlmaDIGSIEFDDFNSFKTQVDKSLKAHAIKLSAPEKNAILNAVSWY  660
            +W+  ++L+++A  L   IG   ++DFN FK  VD  L + ++KLSAPEK+AIL+AVSWY
Sbjct  592  NWMKQRTLVNAASQLHKKIGDEVYNDFNQFKQLVDAELTSLGLKLSAPEKKAILDAVSWY  651

Query  661  DETAKKVVKKIVKLTGDKLNDLLERYECEVADLPDFGYYPVPTTEGGKKGEFITYETNSD  720
            DE A KV+KK+ KL  DKL+DLLE YECE+ DLPDFGYYP      G+  EF+TYE++SD
Sbjct  652  DENAEKVIKKVAKLKQDKLDDLLENYECELEDLPDFGYYP-----TGNHNEFVTYESSSD  706

Query  721  LRDTESVPLKQSIYLYFLDEVKPHVDEAWINLDTVKIGYEISFNKYFYRHKPLRSLEEVA  780
            LRD+ESVPL QSIY YFLDEVKPHVDEAW+NL++VKIGYEISFNKYFYRHKPLRS++EVA
Sbjct  707  LRDSESVPLEQSIYQYFLDEVKPHVDEAWVNLESVKIGYEISFNKYFYRHKPLRSMDEVA  766

Query  781  TDIINLEQKAEGLIAQILGVAVEKVQG  807
             +II LEQKAEGLIA+ILG++V KVQG
Sbjct  767  KEIIALEQKAEGLIADILGISVAKVQG  793

10) PAGR_g3655 in NC_017554


> EU272902|18|G17|167832524|ACA01834.1|Vibrio_cholerae_Amazonia_3509|-|21794..24175|-|VPI2_0017c|DNA 
methylase HsdM
Length=793

 Score = 1044 bits (3958),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 611/802 (77%), Positives = 712/802 (89%), Gaps = 9/802 (1%)

Query  1    MDHSVHNKLISFIWNIADDCLRDVYVRGKYRDVILPMVVLRRLDTLLEPTKEAVLAEVKF  60
            MDHSVHNKL+SFIW+IADDCLRDVYVRGKYRDVILPMVVLRRLDTLLEP+KEAVL EV+F
Sbjct  1    MDHSVHNKLVSFIWSIADDCLRDVYVRGKYRDVILPMVVLRRLDTLLEPSKEAVLEEVRF  60

Query  61   QKEEMQATELDDEPLKSVSGYVFYNTSKWTLKSLFSTATNNQQILLANFEEYLLGFSDNV  120
            QKEEM+  ELDD PL + SGYVFYNTSKWTL++LFSTATNNQQILLANFE+YL GFS+NV
Sbjct  61   QKEEMNEIELDDAPLCATSGYVFYNTSKWTLQTLFSTATNNQQILLANFEDYLNGFSENV  120

Query  121  KEIIECFNLKSQIRHMASKQVLLDVVEKFVSPHINLTPEIVEDPDGNKMPALTNLGMGYV  180
            KEI+ECFNLK+QIRHMA+K+VLLDVVEKFVSP INLTP + EDP+GNK+PAL+NLGMGYV
Sbjct  121  KEIVECFNLKAQIRHMAGKNVLLDVVEKFVSPYINLTPAVKEDPEGNKLPALSNLGMGYV  180

Query  181  FEELIRKFNEENNEEAGEHFTPREVIELMTHLVFDPVKDQLPLTMTVYDPACGSGGMLTE  240
            FEELIRKFNEENNEEAGEHFTPREVIELMTHLVFDP+KD+LPL++TVYDPACGSGGMLTE
Sbjct  181  FEELIRKFNEENNEEAGEHFTPREVIELMTHLVFDPIKDNLPLSITVYDPACGSGGMLTE  240

Query  241  SQNFIEEKYPNESRDIYLYGKEINDETYAICKSDMMIKGNNPENIKVGSTLSTDEFASSR  300
            +QNF+EEKYP  +RDIYLYGKEINDETYAICKSDMMIKGNNPENI+VGSTLSTDEF+S+R
Sbjct  241  TQNFVEEKYPASNRDIYLYGKEINDETYAICKSDMMIKGNNPENIRVGSTLSTDEFSSNR  300

Query  301  FDFMLSNPPYGKSWASEQKHIKDGSDVIDPRFKVSLKDYWGNVEVVDATPRSSDGQLLFL  360
            FDFMLSNPPYGKSWASEQKHIK+G +V+D RFKV LKDYWG     +A PRSSDGQLLFL
Sbjct  301  FDFMLSNPPYGKSWASEQKHIKEGKEVVDGRFKVKLKDYWGVESEQEAIPRSSDGQLLFL  360

Query  361  MEMVNKMKDPGVSPLGSRIASVHNGSSLFTGDAGGGESNIRRLIIENDMLDAIVQLPNNL  420
            MEMV KMK P  SPLGSRIASVHNGSSLFTGDAG+GESNIRR IIENDMLDAIVQLPNNL
Sbjct  361  MEMVTKMKSPQDSPLGSRIASVHNGSSLFTGDAGSGESNIRRYIIENDMLDAIVQLPNNL  420

Query  421  FYNTGITTYIWVLNNNKPVSRKGKVQLIDASLLYRKLRKNLGNKNCEFAPEHITEITDTY  480
            FYNTGITTYIW+LNNNKP +R+GKVQLIDASLL+RKLRKNLGNKNCEF+PEHI+EI  TY
Sbjct  421  FYNTGITTYIWLLNNNKPENRQGKVQLIDASLLFRKLRKNLGNKNCEFSPEHIAEIVSTY  480

Query  481  LSCIDVERQLDTNNDPIGISSKVFSNDDFGYYKVTIERPDRRKARFTQEAIAPLRFDKQF  540
            L    VER +D + DP+GI+++VF N+DFGYYKV IERPDRR+A+F  + I PLRF++  
Sbjct  481  LENQSVERAIDEKGDPVGIAAQVFKNQDFGYYKVNIERPDRRNAQFRADLIEPLRFENSQ  540

Query  541  SDIMMHLYAEYGDNVYNNTGFGSDQKKSFLKSIEKEIFAWCEENEISLNAKARTKLLDVK  600
             ++M  LYAEYG++VY+          +F+K+IEKEI  WCEEN+ISLN  A+TKLLD K
Sbjct  541  REVMEYLYAEYGEQVYDA---------GFVKGIEKEITKWCEENDISLNKAAKTKLLDTK  591

Query  601  HWLALRTVLETAQQLMSDIGDHEFDDFNEFTSLVDKSLKLSGVKLSASEKNVILNAVSWY  660
            +W+  RT++++A QL   IGD+ ++DFN+F  LVD  L   G+KLSA+EK+ IL+AVSWY
Sbjct  592  NWMKQRTLVNAASQLHKKIGDEVYNDFNQFKQLVDAELTSLGLKLSAPEKKAILDAVSWY  651

Query  661  DESAkkvvkkvvkLSGDKLNDLLDRYECEVDDLPDFGYYPSGKKGEYITYETNADLRDFE  720
            DE+A KV+KKV KL  DKL+DLL+ YECE++DLPDFGYYP+G+  E++TYE+++DLRD E
Sbjct  652  DENAEKVIKKVAKLKQDKLDDLLENYECELEDLPDFGYYPTGNHNEFVTYESSSDLRDSE  711

Query  721  SVSLKQSIYEYFLDEVKPYIDEAWINLETVKIGYEINFNKYFYRHKPLRGLEEVAKDIIA  780
            SV+L QSIY+YFLDEVKP +DEAW+NLE+VKIGYEI+FNKYFYRHKPLR+++EVAK+IIA
Sbjct  712  SVPLEQSIYQYFLDEVKPHVDEAWVNLESVKIGYEISFNKYFYRHKPLRSMDEVAKEIIA  771

Query  781  LEQKADGLIANILGVKVKEVQG  802
            LEQKA+GLIA+ILG+ V  VQG
Sbjct  772  LEQKAEGLIADILGISVAKVQG  793

11) hsdM in NC_010694


> EU272902|18|G17|167832524|ACA01834.1|Vibrio_cholerae_Amazonia_3509|-|21794..24175|-|VPI2_0017c|DNA 
methylase HsdM
Length=793

 Score = 1042 bits (3950),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 604/793 (77%), Positives = 708/793 (90%), Gaps = 0/793 (0%)

Query  1    MDHSVHNKLISFIWNIADDCLRDVYVRGKYRDVILPMVVLRRLDTLLEPGKEAVLAEVRF  60
            MDHSVHNKL+SFIW+IADDCLRDVYVRGKYRDVILPMVVLRRLDTLLEP+KEAVL EVRF
Sbjct  1    MDHSVHNKLVSFIWSIADDCLRDVYVRGKYRDVILPMVVLRRLDTLLEPSKEAVLEEVRF  60

Query  61   QKEELQATELDDAPLMAASGYVFYNTSKWTLNSLFKTATNSQQILLANFEEYLLGFSDNV  120
            QKEE++  ELDDAPL A+SGYVFYNTSKWTL++LF TATN+QQILLANFE+YL GFS+NV
Sbjct  61   QKEEMNEIELDDAPLCATSGYVFYNTSKWTLQTLFSTATNNQQILLANFEDYLNGFSENV  120

Query  121  KEIVACFNLQAQIRHMAAKQVLLDVVEKFVSPYINLTHKAVDDPDGYSMPALSNLGMGYV  180
            KEIV CFNL+AQIRHMA+K+VLLDVVEKFVSPYINLT    +DP+G  +PALSNLGMGYV
Sbjct  121  KEIVECFNLKAQIRHMAGKNVLLDVVEKFVSPYINLTPAVKEDPEGNKLPALSNLGMGYV  180

Query  181  FEELIRKFNEENNEEAGEHFTPREVIDLMTHLVFDPVKDKLPLTMTVYDPACGSGGMLTE  240
            FEELIRKFNEENNEEAGEHFTPREVI+LMTHLVFDP+KD+LPL++TVYDPACGSGGMLTE
Sbjct  181  FEELIRKFNEENNEEAGEHFTPREVIELMTHLVFDPIKDNLPLSITVYDPACGSGGMLTE  240

Query  241  SQNFIEAKYPSSNRDIYLYGKEINDETYAICKSDMMIKGNNPENIRVGSTLSTDEFAAQR  300
            +QNF+E KYP+SNRDIYLYGKEINDETYAICKSDMMIKGNNPENIRVGSTLSTDEF+++R
Sbjct  241  TQNFVEEKYPASNRDIYLYGKEINDETYAICKSDMMIKGNNPENIRVGSTLSTDEFSSNR  300

Query  301  FDFMLSNPPYGKSWATEQKYIKDGGDVIDPRFKVKLRDYFGKEETVDATPRSSDGQLLFL  360
            FDFMLSNPPYGKSWA+EQK IK+G +V+D RFKVKL+DY G E   +A PRSSDGQLLFL
Sbjct  301  FDFMLSNPPYGKSWASEQKHIKEGKEVVDGRFKVKLKDYWGVESEQEAIPRSSDGQLLFL  360

Query  361  MEMVSKMKDPAIGSLGSRIASVHNGSSLFTGDAGGGESNIRRYLIENDMLDAIVQLPNNL  420
            MEMV+KMK P  ++LGSRIASVHNGSSLFTGDAG+GESNIRRY+IENDMLDAIVQLPNNL
Sbjct  361  MEMVTKMKSPQDSPLGSRIASVHNGSSLFTGDAGSGESNIRRYIIENDMLDAIVQLPNNL  420

Query  421  FYNTGITTYIWLLNNNKSQDRQGKVQLIDASLLYRKLRKNLGNKNCEFAPEHIAEIAQTY  480
            FYNTGITTYIWLLNNNK+++RQGKVQLIDASLL+RKLRKNLGNKNCEF+PEHIAEI  TY
Sbjct  421  FYNTGITTYIWLLNNNKPENRQGKVQLIDASLLFRKLRKNLGNKNCEFSPEHIAEIVSTY  480

Query  481  LACTGAERALDANHDAVGIASKVFSNDDFGYYKVTIERPDRRKARFSREAIRPLRFDKQL  540
            L   + ERA+D + D+VGIA++VF N+DFGYYKV IERPDRR+A+F  + I PLRF++  
Sbjct  481  LENQSVERAIDEKGDPVGIAAQVFKNQDFGYYKVNIERPDRRNAQFRADLIEPLRFENSQ  540

Query  541  AEVMAWLYAEHGDKVYEKGFLASVEKDTQGWCAERDISLNTKARSKLLDVKNWLSLQTVY  600
             EVM  LYAE G++VY+ GF+ ++EK+   WC E DISLN  A++KLLD KNW+  +T+ 
Sbjct  541  REVMEYLYAEYGEQVYDAGFVKGIEKEITKWCEENDISLNKAAKTKLLDTKNWMKQRTLV  600

Query  601  HCAERLMATIGGEEFDDFNRFKAQVEQVLKAEKIKLSAAEKNAILNAVSWYDESAAKVIN  660
            + A +L   IG+E ++DFN+FK  V+  L +  +KLSA+EK+AIL+AVSWYDE+A KVI+
Sbjct  601  NAASQLHKKIGDEVYNDFNQFKQLVDAELTSLGLKLSAPEKKAILDAVSWYDENAEKVIK  660

Query  661  KTVKLNGDKLQDLLERLECEAADLPDFGFYPSGKKDEYITYDSSADLRDTESIPLKQSIY  720
            K  KL+ DKL+DLLE  ECE  DLPDFG+YP+G+ +E++TY+SS+DLRD+ES+PL QSIY
Sbjct  661  KVAKLKQDKLDDLLENYECELEDLPDFGYYPTGNHNEFVTYESSSDLRDSESVPLEQSIY  720

Query  721  QYFLDEVKPHVAEAWINLDSVKIGYEISFNKYFYRHKPLRSLEEVAQDIIKLEQQSEGLI  780
            QYFLDEVKPHV EAW+NL+SVKIGYEISFNKYFYRHKPLRS++EVA++II LEQ++EGLI
Sbjct  721  QYFLDEVKPHVDEAWVNLESVKIGYEISFNKYFYRHKPLRSMDEVAKEIIALEQKAEGLI  780

Query  781  AQILGISVDKIQG  793
            A+ILGISV K+QG
Sbjct  781  ADILGISVAKVQG  793

12) amad1_05825 in NC_019393


> EU272902|18|G17|167832524|ACA01834.1|Vibrio_cholerae_Amazonia_3509|-|21794..24175|-|VPI2_0017c|DNA 
methylase HsdM
Length=793

 Score = 1036 bits (3926),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 622/807 (78%), Positives = 712/807 (89%), Gaps = 14/807 (1%)

Query  1    MDHSVHNKLISFIWNIADDCLRDVYVRGKYRDVILPMVVLRRLDTLLEPTKEAVLEEVKF  60
            MDHSVHNKL+SFIW+IADDCLRDVYVRGKYRDVILPMVVLRRLDTLLEP+KEAVLEEV+F
Sbjct  1    MDHSVHNKLVSFIWSIADDCLRDVYVRGKYRDVILPMVVLRRLDTLLEPSKEAVLEEVRF  60

Query  61   QKEEMQATELDDEPLKAASGYVFYNTSKWTLKSLFNTATNNQQILLANFEEYLLGFSDNV  120
            QKEEM+  ELDD PL A+SGYVFYNTSKWTL++LF+TATNNQQILLANFE+YL GFS+NV
Sbjct  61   QKEEMNEIELDDAPLCATSGYVFYNTSKWTLQTLFSTATNNQQILLANFEDYLNGFSENV  120

Query  121  KEIIECFNLKSQIRHMASKQVLLDVVEKFVSPYINLTHETVEDPDGNKMPALTNLGMGYV  180
            KEI+ECFNLK+QIRHMA+K+VLLDVVEKFVSPYINLT    EDP+GNK+PAL+NLGMGYV
Sbjct  121  KEIVECFNLKAQIRHMAGKNVLLDVVEKFVSPYINLTPAVKEDPEGNKLPALSNLGMGYV  180

Query  181  FEELIRKFNEENNEEAGEHFTPREVIELMTHLVFDPVKDQLPLTMTVYDPACGSGGMLTE  240
            FEELIRKFNEENNEEAGEHFTPREVIELMTHLVFDP+KD+LPL++TVYDPACGSGGMLTE
Sbjct  181  FEELIRKFNEENNEEAGEHFTPREVIELMTHLVFDPIKDNLPLSITVYDPACGSGGMLTE  240

Query  241  SQNFIEEKYPNDSRDVYLYGKEINDETYAICKSDMMIKGNNPENIKVGSTLSTDEFAASR  300
            +QNF+EEKYP  +RD+YLYGKEINDETYAICKSDMMIKGNNPENI+VGSTLSTDEF+++R
Sbjct  241  TQNFVEEKYPASNRDIYLYGKEINDETYAICKSDMMIKGNNPENIRVGSTLSTDEFSSNR  300

Query  301  FDFMLSNPPYGKSWASEQKHIKDGSDVIDPRFKVSLKDYWGNLEVVDATPRSSDGQLLFL  360
            FDFMLSNPPYGKSWASEQKHIK+G +V+D RFKV LKDYWG     +A PRSSDGQLLFL
Sbjct  301  FDFMLSNPPYGKSWASEQKHIKEGKEVVDGRFKVKLKDYWGVESEQEAIPRSSDGQLLFL  360

Query  361  MEMVNKMKDPSVSPLGSRIASVHNGSSLFTGDAGGGESNIRRFIIENDMLDAIVQLPNNL  420
            MEMV KMK P  SPLGSRIASVHNGSSLFTGDAG+GESNIRR+IIENDMLDAIVQLPNNL
Sbjct  361  MEMVTKMKSPQDSPLGSRIASVHNGSSLFTGDAGSGESNIRRYIIENDMLDAIVQLPNNL  420

Query  421  FYNTGITTYIWVLNNNKPEARKGKVQLIDASLLYRKLRKNLGNKNCEFAPEHITEITDTY  480
            FYNTGITTYIW+LNNNKPE R+GKVQLIDASLL+RKLRKNLGNKNCEF+PEHI+EI  TY
Sbjct  421  FYNTGITTYIWLLNNNKPENRQGKVQLIDASLLFRKLRKNLGNKNCEFSPEHIAEIVSTY  480

Query  481  LACMDVERALDANNDPIGIASKVFSNDDFGYYKVTIERPDRRRAKFTQDAIAPLRFDKQL  540
            L    VERA+D + DP+GIA++VF N+DFGYYKV IERPDRR A+F  D I PLRF++  
Sbjct  481  LENQSVERAIDEKGDPVGIAAQVFKNQDFGYYKVNIERPDRRNAQFRADLIEPLRFENSQ  540

Query  541  SEVMEHVYAEHGERVYEKTGYGSDQKKSFLKSIEKDILSWCEDNDISLNAKAKAKLLDVK  600
             EVME +YAE GE+VY+          +F+K+IEK+I  WCE+NDISLN  AK+KLLD K
Sbjct  541  REVMEYLYAEYGEQVYD---------AGFVKGIEKEITKWCEENDISLNKAAKTKLLDTK  591

Query  601  HWLALKALLETAQTLMADIGSNEFDDFNSFKTQVDKSLKAHAIKLSAPEKNAILNAVSWY  660
            +W+  ++L+++A  L   IG + ++DFN FK  VD  L + ++KLSAPEK+AIL+AVSWY
Sbjct  592  NWMKQRTLVNAASQLHKKIGDEVYNDFNQFKQLVDAELTSLGLKLSAPEKKAILDAVSWY  651

Query  661  DETAkkvvkkvvkltgdklddllERYECEVADLPDFGYYPVPREEGGKKGEFITYETNSD  720
            DE A KV+KKV KL  DKLDDLLE YECE+ DLPDFGYYP      G+  EF+TYE++SD
Sbjct  652  DENAEKVIKKVAKLKQDKLDDLLENYECELEDLPDFGYYP-----TGNHNEFVTYESSSD  706

Query  721  LRDTESVPLKQSIYQYFLDEVKPHVDEAWINLDTVKIGYEISFNKYFYRHKPLRSLEEVA  780
            LRD+ESVPL QSIYQYFLDEVKPHVDEAW+NL++VKIGYEISFNKYFYRHKPLRS++EVA
Sbjct  707  LRDSESVPLEQSIYQYFLDEVKPHVDEAWVNLESVKIGYEISFNKYFYRHKPLRSMDEVA  766

Query  781  TDIINLEQKAEGLIAQILGVNVAEVQG  807
             +II LEQKAEGLIA+ILG++VA VQG
Sbjct  767  KEIIALEQKAEGLIADILGISVAKVQG  793

13) I636_05840 in NC_021714


> EU272902|18|G17|167832524|ACA01834.1|Vibrio_cholerae_Amazonia_3509|-|21794..24175|-|VPI2_0017c|DNA 
methylase HsdM
Length=793

 Score = 1036 bits (3926),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 622/807 (78%), Positives = 712/807 (89%), Gaps = 14/807 (1%)

Query  1    MDHSVHNKLISFIWNIADDCLRDVYVRGKYRDVILPMVVLRRLDTLLEPTKEAVLEEVKF  60
            MDHSVHNKL+SFIW+IADDCLRDVYVRGKYRDVILPMVVLRRLDTLLEP+KEAVLEEV+F
Sbjct  1    MDHSVHNKLVSFIWSIADDCLRDVYVRGKYRDVILPMVVLRRLDTLLEPSKEAVLEEVRF  60

Query  61   QKEEMQATELDDEPLKAASGYVFYNTSKWTLKSLFNTATNNQQILLANFEEYLLGFSDNV  120
            QKEEM+  ELDD PL A+SGYVFYNTSKWTL++LF+TATNNQQILLANFE+YL GFS+NV
Sbjct  61   QKEEMNEIELDDAPLCATSGYVFYNTSKWTLQTLFSTATNNQQILLANFEDYLNGFSENV  120

Query  121  KEIIECFNLKSQIRHMASKQVLLDVVEKFVSPYINLTHETVEDPDGNKMPALTNLGMGYV  180
            KEI+ECFNLK+QIRHMA+K+VLLDVVEKFVSPYINLT    EDP+GNK+PAL+NLGMGYV
Sbjct  121  KEIVECFNLKAQIRHMAGKNVLLDVVEKFVSPYINLTPAVKEDPEGNKLPALSNLGMGYV  180

Query  181  FEELIRKFNEENNEEAGEHFTPREVIELMTHLVFDPVKDQLPLTMTVYDPACGSGGMLTE  240
            FEELIRKFNEENNEEAGEHFTPREVIELMTHLVFDP+KD+LPL++TVYDPACGSGGMLTE
Sbjct  181  FEELIRKFNEENNEEAGEHFTPREVIELMTHLVFDPIKDNLPLSITVYDPACGSGGMLTE  240

Query  241  SQNFIEEKYPNDSRDVYLYGKEINDETYAICKSDMMIKGNNPENIKVGSTLSTDEFAASR  300
            +QNF+EEKYP  +RD+YLYGKEINDETYAICKSDMMIKGNNPENI+VGSTLSTDEF+++R
Sbjct  241  TQNFVEEKYPASNRDIYLYGKEINDETYAICKSDMMIKGNNPENIRVGSTLSTDEFSSNR  300

Query  301  FDFMLSNPPYGKSWASEQKHIKDGSDVIDPRFKVSLKDYWGNLEVVDATPRSSDGQLLFL  360
            FDFMLSNPPYGKSWASEQKHIK+G +V+D RFKV LKDYWG     +A PRSSDGQLLFL
Sbjct  301  FDFMLSNPPYGKSWASEQKHIKEGKEVVDGRFKVKLKDYWGVESEQEAIPRSSDGQLLFL  360

Query  361  MEMVNKMKDPSVSPLGSRIASVHNGSSLFTGDAGGGESNIRRFIIENDMLDAIVQLPNNL  420
            MEMV KMK P  SPLGSRIASVHNGSSLFTGDAG+GESNIRR+IIENDMLDAIVQLPNNL
Sbjct  361  MEMVTKMKSPQDSPLGSRIASVHNGSSLFTGDAGSGESNIRRYIIENDMLDAIVQLPNNL  420

Query  421  FYNTGITTYIWVLNNNKPEARKGKVQLIDASLLYRKLRKNLGNKNCEFAPEHITEITDTY  480
            FYNTGITTYIW+LNNNKPE R+GKVQLIDASLL+RKLRKNLGNKNCEF+PEHI+EI  TY
Sbjct  421  FYNTGITTYIWLLNNNKPENRQGKVQLIDASLLFRKLRKNLGNKNCEFSPEHIAEIVSTY  480

Query  481  LACMDVERALDANNDPIGIASKVFSNDDFGYYKVTIERPDRRRAKFTQDAIAPLRFDKQL  540
            L    VERA+D + DP+GIA++VF N+DFGYYKV IERPDRR A+F  D I PLRF++  
Sbjct  481  LENQSVERAIDEKGDPVGIAAQVFKNQDFGYYKVNIERPDRRNAQFRADLIEPLRFENSQ  540

Query  541  SEVMEHVYAEHGERVYEKTGYGSDQKKSFLKSIEKDILSWCEDNDISLNAKAKAKLLDVK  600
             EVME +YAE GE+VY+          +F+K+IEK+I  WCE+NDISLN  AK+KLLD K
Sbjct  541  REVMEYLYAEYGEQVYD---------AGFVKGIEKEITKWCEENDISLNKAAKTKLLDTK  591

Query  601  HWLALKALLETAQTLMADIGSNEFDDFNSFKTQVDKSLKAHAIKLSAPEKNAILNAVSWY  660
            +W+  ++L+++A  L   IG + ++DFN FK  VD  L + ++KLSAPEK+AIL+AVSWY
Sbjct  592  NWMKQRTLVNAASQLHKKIGDEVYNDFNQFKQLVDAELTSLGLKLSAPEKKAILDAVSWY  651

Query  661  DETAkkvvkkvvkltgdklddllERYECEVADLPDFGYYPVPREEGGKKGEFITYETNSD  720
            DE A KV+KKV KL  DKLDDLLE YECE+ DLPDFGYYP      G+  EF+TYE++SD
Sbjct  652  DENAEKVIKKVAKLKQDKLDDLLENYECELEDLPDFGYYP-----TGNHNEFVTYESSSD  706

Query  721  LRDTESVPLKQSIYQYFLDEVKPHVDEAWINLDTVKIGYEISFNKYFYRHKPLRSLEEVA  780
            LRD+ESVPL QSIYQYFLDEVKPHVDEAW+NL++VKIGYEISFNKYFYRHKPLRS++EVA
Sbjct  707  LRDSESVPLEQSIYQYFLDEVKPHVDEAWVNLESVKIGYEISFNKYFYRHKPLRSMDEVA  766

Query  781  TDIINLEQKAEGLIAQILGVNVAEVQG  807
             +II LEQKAEGLIA+ILG++VA VQG
Sbjct  767  KEIIALEQKAEGLIADILGISVAKVQG  793

14) I635_05805 in NC_021713


> EU272902|18|G17|167832524|ACA01834.1|Vibrio_cholerae_Amazonia_3509|-|21794..24175|-|VPI2_0017c|DNA 
methylase HsdM
Length=793

 Score = 1036 bits (3926),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 622/807 (78%), Positives = 712/807 (89%), Gaps = 14/807 (1%)

Query  1    MDHSVHNKLISFIWNIADDCLRDVYVRGKYRDVILPMVVLRRLDTLLEPTKEAVLEEVKF  60
            MDHSVHNKL+SFIW+IADDCLRDVYVRGKYRDVILPMVVLRRLDTLLEP+KEAVLEEV+F
Sbjct  1    MDHSVHNKLVSFIWSIADDCLRDVYVRGKYRDVILPMVVLRRLDTLLEPSKEAVLEEVRF  60

Query  61   QKEEMQATELDDEPLKAASGYVFYNTSKWTLKSLFNTATNNQQILLANFEEYLLGFSDNV  120
            QKEEM+  ELDD PL A+SGYVFYNTSKWTL++LF+TATNNQQILLANFE+YL GFS+NV
Sbjct  61   QKEEMNEIELDDAPLCATSGYVFYNTSKWTLQTLFSTATNNQQILLANFEDYLNGFSENV  120

Query  121  KEIIECFNLKSQIRHMASKQVLLDVVEKFVSPYINLTHETVEDPDGNKMPALTNLGMGYV  180
            KEI+ECFNLK+QIRHMA+K+VLLDVVEKFVSPYINLT    EDP+GNK+PAL+NLGMGYV
Sbjct  121  KEIVECFNLKAQIRHMAGKNVLLDVVEKFVSPYINLTPAVKEDPEGNKLPALSNLGMGYV  180

Query  181  FEELIRKFNEENNEEAGEHFTPREVIELMTHLVFDPVKDQLPLTMTVYDPACGSGGMLTE  240
            FEELIRKFNEENNEEAGEHFTPREVIELMTHLVFDP+KD+LPL++TVYDPACGSGGMLTE
Sbjct  181  FEELIRKFNEENNEEAGEHFTPREVIELMTHLVFDPIKDNLPLSITVYDPACGSGGMLTE  240

Query  241  SQNFIEEKYPNDSRDVYLYGKEINDETYAICKSDMMIKGNNPENIKVGSTLSTDEFAASR  300
            +QNF+EEKYP  +RD+YLYGKEINDETYAICKSDMMIKGNNPENI+VGSTLSTDEF+++R
Sbjct  241  TQNFVEEKYPASNRDIYLYGKEINDETYAICKSDMMIKGNNPENIRVGSTLSTDEFSSNR  300

Query  301  FDFMLSNPPYGKSWASEQKHIKDGSDVIDPRFKVSLKDYWGNLEVVDATPRSSDGQLLFL  360
            FDFMLSNPPYGKSWASEQKHIK+G +V+D RFKV LKDYWG     +A PRSSDGQLLFL
Sbjct  301  FDFMLSNPPYGKSWASEQKHIKEGKEVVDGRFKVKLKDYWGVESEQEAIPRSSDGQLLFL  360

Query  361  MEMVNKMKDPSVSPLGSRIASVHNGSSLFTGDAGGGESNIRRFIIENDMLDAIVQLPNNL  420
            MEMV KMK P  SPLGSRIASVHNGSSLFTGDAG+GESNIRR+IIENDMLDAIVQLPNNL
Sbjct  361  MEMVTKMKSPQDSPLGSRIASVHNGSSLFTGDAGSGESNIRRYIIENDMLDAIVQLPNNL  420

Query  421  FYNTGITTYIWVLNNNKPEARKGKVQLIDASLLYRKLRKNLGNKNCEFAPEHITEITDTY  480
            FYNTGITTYIW+LNNNKPE R+GKVQLIDASLL+RKLRKNLGNKNCEF+PEHI+EI  TY
Sbjct  421  FYNTGITTYIWLLNNNKPENRQGKVQLIDASLLFRKLRKNLGNKNCEFSPEHIAEIVSTY  480

Query  481  LACMDVERALDANNDPIGIASKVFSNDDFGYYKVTIERPDRRRAKFTQDAIAPLRFDKQL  540
            L    VERA+D + DP+GIA++VF N+DFGYYKV IERPDRR A+F  D I PLRF++  
Sbjct  481  LENQSVERAIDEKGDPVGIAAQVFKNQDFGYYKVNIERPDRRNAQFRADLIEPLRFENSQ  540

Query  541  SEVMEHVYAEHGERVYEKTGYGSDQKKSFLKSIEKDILSWCEDNDISLNAKAKAKLLDVK  600
             EVME +YAE GE+VY+          +F+K+IEK+I  WCE+NDISLN  AK+KLLD K
Sbjct  541  REVMEYLYAEYGEQVYD---------AGFVKGIEKEITKWCEENDISLNKAAKTKLLDTK  591

Query  601  HWLALKALLETAQTLMADIGSNEFDDFNSFKTQVDKSLKAHAIKLSAPEKNAILNAVSWY  660
            +W+  ++L+++A  L   IG + ++DFN FK  VD  L + ++KLSAPEK+AIL+AVSWY
Sbjct  592  NWMKQRTLVNAASQLHKKIGDEVYNDFNQFKQLVDAELTSLGLKLSAPEKKAILDAVSWY  651

Query  661  DETAkkvvkkvvkltgdklddllERYECEVADLPDFGYYPVPREEGGKKGEFITYETNSD  720
            DE A KV+KKV KL  DKLDDLLE YECE+ DLPDFGYYP      G+  EF+TYE++SD
Sbjct  652  DENAEKVIKKVAKLKQDKLDDLLENYECELEDLPDFGYYP-----TGNHNEFVTYESSSD  706

Query  721  LRDTESVPLKQSIYQYFLDEVKPHVDEAWINLDTVKIGYEISFNKYFYRHKPLRSLEEVA  780
            LRD+ESVPL QSIYQYFLDEVKPHVDEAW+NL++VKIGYEISFNKYFYRHKPLRS++EVA
Sbjct  707  LRDSESVPLEQSIYQYFLDEVKPHVDEAWVNLESVKIGYEISFNKYFYRHKPLRSMDEVA  766

Query  781  TDIINLEQKAEGLIAQILGVNVAEVQG  807
             +II LEQKAEGLIA+ILG++VA VQG
Sbjct  767  KEIIALEQKAEGLIADILGISVAKVQG  793

15) MEALZ_3669 in NC_016112


> EU272902|18|G17|167832524|ACA01834.1|Vibrio_cholerae_Amazonia_3509|-|21794..24175|-|VPI2_0017c|DNA 
methylase HsdM
Length=793

 Score = 1032 bits (3910),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 606/793 (77%), Positives = 705/793 (89%), Gaps = 8/793 (1%)

Query  1    MDHSVHNKLISFIWNIADDCLRDVYVRGKYRDVILPMVVLRRLDTLLEPTKEAVLEEVKF  60
            MDHSVHNKL+SFIW+IADDCLRDVYVRGKYRDVILPMVVLRRLDTLLEP+KEAVLEEV+F
Sbjct  1    MDHSVHNKLVSFIWSIADDCLRDVYVRGKYRDVILPMVVLRRLDTLLEPSKEAVLEEVRF  60

Query  61   QKEEMQATELDDEPLKAASGYVFYNTSKWTLKSLFNTATNNQQILLANFEEYLLGFSDNV  120
            QKEEM+  ELDD PL A+SGYVFYNTSKWTL++LF+TATNNQQILLANFE+YL GFS+NV
Sbjct  61   QKEEMNEIELDDAPLCATSGYVFYNTSKWTLQTLFSTATNNQQILLANFEDYLNGFSENV  120

Query  121  KEIIECFNLKSQIRHMASKQVLLDVVEKFVSPYINLTHESVEDPNGNKMPALTNLGMGYV  180
            KEI+ECFNLK+QIRHMA+K+VLLDVVEKFVSPYINLT    EDP+GNK+PAL+NLGMGYV
Sbjct  121  KEIVECFNLKAQIRHMAGKNVLLDVVEKFVSPYINLTPAVKEDPEGNKLPALSNLGMGYV  180

Query  181  FEELIRKFNEENNEEAGEHFTPREVIELMTHLVFDPVKDRLPLTMTVYDPACGSGGMLTE  240
            FEELIRKFNEENNEEAGEHFTPREVIELMTHLVFDP+KD LPL++TVYDPACGSGGMLTE
Sbjct  181  FEELIRKFNEENNEEAGEHFTPREVIELMTHLVFDPIKDNLPLSITVYDPACGSGGMLTE  240

Query  241  SQNFIEEKYPNDNRDVYLYGKEINDETYAICKSDMMIKGNNPENIREGSTLSTDEFAGTK  300
            +QNF+EEKYP  NRD+YLYGKEINDETYAICKSDMMIKGNNPENIR GSTLSTDEF++ +
Sbjct  241  TQNFVEEKYPASNRDIYLYGKEINDETYAICKSDMMIKGNNPENIRVGSTLSTDEFSSNR  300

Query  301  FDFMLSNPPYGKSWAGEQKHIKDGSDVIDPRFKVNLKDYWGNEEVVDATPRSSDGQLLFL  360
            FDFMLSNPPYGKSWA+EQKHIK+G +V+D RFKV+LKDYWG E   +A PRSSDGQLLFL
Sbjct  301  FDFMLSNPPYGKSWASEQKHIKEGKEVVDGRFKVKLKDYWGVESEQEAIPRSSDGQLLFL  360

Query  361  MEMVSKMKDPAVSPLGTRIASVHNGSSLFTGDAGGGESNIRRYIIENDRLDVIVQLPNNL  420
            MEMV+KMK P  SPLG+RIASVHNGSSLFTGDAG+GESNIRRYIIEND LD IVQLPNNL
Sbjct  361  MEMVTKMKSPQDSPLGSRIASVHNGSSLFTGDAGSGESNIRRYIIENDMLDAIVQLPNNL  420

Query  421  FYNTGITTYIWVLNNNKPESRQGKVQLIDASLLFRKLRKNLGNKNCEFAPEHIEEITHTY  480
            FYNTGITTYIW+LNNNKPE+RQGKVQLIDASLLFRKLRKNLGNKNCEF+PEHI EI  TY
Sbjct  421  FYNTGITTYIWLLNNNKPENRQGKVQLIDASLLFRKLRKNLGNKNCEFSPEHIAEIVSTY  480

Query  481  LACAEVERQLNDNQDPIGLASKVFNNADFGYYKVSIERPDRRKAQFTPEAIAPLRFDKAL  540
            L    VER ++++ DP+G+A++VF+N DFGYYKV+IERPDRR+AQF ++ I PLRF+++ 
Sbjct  481  LENQSVERAIDEKGDPVGIAAQVFKNQDFGYYKVNIERPDRRNAQFRADLIEPLRFENSQ  540

Query  541  SEVMEHLYQEHGERVYDAGFLKSIDKAILSWCEDNDISLNTKAKSKLLDVKHWLSLQAQH  600
             EVME LY E GE+VYDAGF+K+I+K I  WCE+NDISLN  AK+KLLD K+W+  ++  
Sbjct  541  REVMEYLYAEYGEQVYDAGFVKGIEKEITKWCEENDISLNKAAKTKLLDTKNWMKQRTLV  600

Query  601  RVATELMAAIGQEEYNDYNQFKELVEAQLKAQKTKLSASEKNAILNAVSWYDDSAAkvvk  660
              A++L   IG+E YND+NQFK+LV+A+L +   KLSA+EK+AIL+AVSWYD++A KV+K
Sbjct  601  NAASQLHKKIGDEVYNDFNQFKQLVDAELTSLGLKLSAPEKKAILDAVSWYDENAEKVIK  660

Query  661  kvvkLSNDKMTELLERYQCTEADLPDFGYYLLKG-NEFITYESSADLRDSESIPLAYPAK  719
            KV KL +DK+ +LLE Y+C   DLPDFGYY     NEF+TYESS+DLRDSES+PL     
Sbjct  661  KVAKLKQDKLDDLLENYECELEDLPDFGYYPTGNHNEFVTYESSSDLRDSESVPL-----  715

Query  720  GEHSAIHQYFVNEVQPHVDEAWLNLDSVKIGYEISFNKYFYRHKPLRSLEEVATDIIHLE  779
              + +I QYF++EV+PHVDEAW+NL+SVKIGYEISFNKYFYRHKPLRS++EVA +II LE
Sbjct  716  --EQSIYQYFLDEVKPHVDEAWVNLESVKIGYEISFNKYFYRHKPLRSMDEVAKEIIALE  773

Query  780  QQAEGLIANILGL  792
            Q+AEGLIA+ILG+
Sbjct  774  QKAEGLIADILGI  786

16) HDN1F_11600 in NC_014366


> EU272902|18|G17|167832524|ACA01834.1|Vibrio_cholerae_Amazonia_3509|-|21794..24175|-|VPI2_0017c|DNA 
methylase HsdM
Length=793

 Score = 1031 bits (3909),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 608/808 (76%), Positives = 708/808 (88%), Gaps = 15/808 (1%)

Query  1    MNHSVHNKLVSFIWSIADDCLRDVYVRGKYRDVILPMVVLRRLDTLLEPTKEAVLEEVRY  60
            M+HSVHNKLVSFIWSIADDCLRDVYVRGKYRDVILPMVVLRRLDTLLEP+KEAVLEEVR+
Sbjct  1    MDHSVHNKLVSFIWSIADDCLRDVYVRGKYRDVILPMVVLRRLDTLLEPSKEAVLEEVRF  60

Query  61   QKEEMQATELDEEPLKEASGYVFYNVSKWTLTSLHNTATNNRQILLANFDEYLNGFSANV  120
            QKEEM+  ELD+ PL  +SGYVFYN SKWTL +L +TATNN+QILLANF++YLNGFS NV
Sbjct  61   QKEEMNEIELDDAPLCATSGYVFYNTSKWTLQTLFSTATNNQQILLANFEDYLNGFSENV  120

Query  121  QEIIERFELKSKIQHMANKDVLLDVVEKFISPKINLTPVAAEDPDGYKLPALSNLGMGYV  180
            +EI+E F+LK++I+HMA K+VLLDVVEKF+SP INLTP   EDP+G KLPALSNLGMGYV
Sbjct  121  KEIVECFNLKAQIRHMAGKNVLLDVVEKFVSPYINLTPAVKEDPEGNKLPALSNLGMGYV  180

Query  181  FEELIRKFNEENNEEAGEHFTPREVIELMTHLVFDPIKDSIPLTLTVYDPACGSGGMLTE  240
            FEELIRKFNEENNEEAGEHFTPREVIELMTHLVFDPIKD++PL++TVYDPACGSGGMLTE
Sbjct  181  FEELIRKFNEENNEEAGEHFTPREVIELMTHLVFDPIKDNLPLSITVYDPACGSGGMLTE  240

Query  241  SQNFIEEKYPADPSAKSQRDIYLYGKEINDETYAICKSDMMIKGNNPENIKVGSTLSTDE  300
            +QNF+EEKYPA     S+RDIYLYGKEINDETYAICKSDMMIKGNNPENI+VGSTLSTDE
Sbjct  241  TQNFVEEKYPA-----SNRDIYLYGKEINDETYAICKSDMMIKGNNPENIRVGSTLSTDE  295

Query  301  FASLRFDFMLSNPPYGKSWASEQKYIKDGSDVIDPRFKVKLKDYWGNIEECDATPRSSDG  360
            F+S RFDFMLSNPPYGKSWASEQK IK+G +V+D RFKVKLKDYWG   E +A PRSSDG
Sbjct  296  FSSNRFDFMLSNPPYGKSWASEQKHIKEGKEVVDGRFKVKLKDYWGVESEQEAIPRSSDG  355

Query  361  QLLFLMEMVSKMKDPGAGTNGSRIASVHNGSSLFTGDAGGGESNIRRYIIENDMLDAIVQ  420
            QLLFLMEMV+KMK P  +  GSRIASVHNGSSLFTGDAG+GESNIRRYIIENDMLDAIVQ
Sbjct  356  QLLFLMEMVTKMKSPQDSPLGSRIASVHNGSSLFTGDAGSGESNIRRYIIENDMLDAIVQ  415

Query  421  LPNNLFYNTGITTYIWLLNNNKPESRKGKVQLIDASLLYRKLRKNLGNKNCEFAPEHIEQ  480
            LPNNLFYNTGITTYIWLLNNNKPE+R+GKVQLIDASLL+RKLRKNLGNKNCEF+PEHI +
Sbjct  416  LPNNLFYNTGITTYIWLLNNNKPENRQGKVQLIDASLLFRKLRKNLGNKNCEFSPEHIAE  475

Query  481  ITRAYLDCAAIERELDGSLPEGMGDPIGIASQVFRNEDFGYYKVTIERPDRRKAQFTAER  540
            I  +YL+  ++ER +D       GDP+GIA+QVF+N+DFGYYKV IERPDRR+AQF A+ 
Sbjct  476  IVSTYLENQSVERAID-----EKGDPVGIAAQVFKNQDFGYYKVNIERPDRRNAQFRADL  530

Query  541  IAGLRFDKQLSEVMEHLYAEYGDKLYEKGFLKSIEKNILAWCEDNDISLNAKAKTKLLDV  600
            I  LRF++   EVME LYAEYG+++Y+ GF+K+IEK+I  WCE+NDISLN  AKTKLLD 
Sbjct  531  IEPLRFENSQREVMEYLYAEYGEQVYDAGFVKGIEKEITKWCEENDISLNKAAKTKLLDT  590

Query  601  KHWLALKAVYETAQALMAAIGKDEFDDFNLFKDQVDAGLKALKVKLSATEKNAILNAVSW  660
            K+W+  +++ ++A  L   IG + ++DFN FK+ VDA L +L +KLSA EK+AIL+AVSW
Sbjct  591  KNWMKQRTLVNAASQLHKKIGDEVYNDFNQFKQLVDAELTSLGLKLSAPEKKAILDAVSW  650

Query  661  YDESAAKVIKKVVKLSGDKLDEVLERYGCTQAQLPDFGFYPTNKKNEYITYETSADLRDS  720
            YDE+A KVIKKV KL  DKLD++LE Y C   +LPDFG+YPT + NE++TYE+S+DLRDS
Sbjct  651  YDENAEKVIKKVAKLKQDKLDDLLENYECELEDLPDFGYYPTGNHNEFVTYESSSDLRDS  710

Query  721  ESVSLLKDDEPQSIHQYFLDEVKPHVEESWINLDSVKIGYEISFNKYFYRHKPLRSLEDV  780
            ESV+L      QSI QYFLDEVKPHV+E+W+NL+SVKIGYEISFNKYFYRHKPLRS+++V
Sbjct  711  ESVPL-----EQSIYQYFLDEVKPHVDEAWVNLESVKIGYEISFNKYFYRHKPLRSMDEV  765

Query  781  AKDIINLEQKAEGLIAQILGVDIEQVQG  808
            AK+II LEQKAEGLIA+ILG+ + +VQG
Sbjct  766  AKEIIALEQKAEGLIADILGISVAKVQG  793

17) hsdM in NC_017390


> EU272902|18|G17|167832524|ACA01834.1|Vibrio_cholerae_Amazonia_3509|-|21794..24175|-|VPI2_0017c|DNA 
methylase HsdM
Length=793

 Score = 1029 bits (3901),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 596/793 (76%), Positives = 701/793 (89%), Gaps = 0/793 (0%)

Query  1    MDHSVHNKLISFIWNIADDCLRDVYVRGKYRDVILPMVVLRRLDTLLEPGKEAVLAEVKF  60
            MDHSVHNKL+SFIW+IADDCLRDVYVRGKYRDVILPMVVLRRLDTLLEP+KEAVL EV+F
Sbjct  1    MDHSVHNKLVSFIWSIADDCLRDVYVRGKYRDVILPMVVLRRLDTLLEPSKEAVLEEVRF  60

Query  61   QKEELRATELDDAPLMAASGYVFYNTSKWTLNLLFKAATNNQQILLANFEEYLLGFSDNV  120
            QKEE+   ELDDAPL A+SGYVFYNTSKWTL+ LF +ATNNQQILLANFE+YL GFS+NV
Sbjct  61   QKEEMNEIELDDAPLCATSGYVFYNTSKWTLQTLFSTATNNQQILLANFEDYLNGFSENV  120

Query  121  KEIVACFNLQAQIRHMASKQVLLDVVEKFVSPYINLTHKAVEDPEGYTMPALSNLGMGYV  180
            KEIV CFNL+AQIRHMA+K+VLLDVVEKFVSPYINLT    EDPEG  +PALSNLGMGYV
Sbjct  121  KEIVECFNLKAQIRHMAGKNVLLDVVEKFVSPYINLTPAVKEDPEGNKLPALSNLGMGYV  180

Query  181  FEELIRKFNEENNEEAGEHFTPREVIDLMTHLVFDPVKDKLPLTMTVYDPACGSGGMLTE  240
            FEELIRKFNEENNEEAGEHFTPREVI+LMTHLVFDP+KD+LPL++TVYDPACGSGGMLTE
Sbjct  181  FEELIRKFNEENNEEAGEHFTPREVIELMTHLVFDPIKDNLPLSITVYDPACGSGGMLTE  240

Query  241  SQNFIEAKYPSSNRDIYLYGKEINDETYAICKSDMMIKGNNPENIRVGSTLSTDEFAAER  300
            +QNF+E KYP+SNRDIYLYGKEINDETYAICKSDMMIKGNNPENIRVGSTLSTDEF+++R
Sbjct  241  TQNFVEEKYPASNRDIYLYGKEINDETYAICKSDMMIKGNNPENIRVGSTLSTDEFSSNR  300

Query  301  FDFMLSNPPYGKSWASEQKYIKDGGDVIDPRFKVRLQDYSGKEETVDATPRSSDGQLLFL  360
            FDFMLSNPPYGKSWASEQK IK+G +V+D RFKV+L+DY G E   +A PRSSDGQLLFL
Sbjct  301  FDFMLSNPPYGKSWASEQKHIKEGKEVVDGRFKVKLKDYWGVESEQEAIPRSSDGQLLFL  360

Query  361  MEMVSKMKDPAIGSLGSRIASVHNGSSLFTGDAGGGESNIRRYLIENDMLDAIVQLPNNL  420
            MEMV+KMK P  ++LGSRIASVHNGSSLFTGDAG+GESNIRRY+IENDMLDAIVQLPNNL
Sbjct  361  MEMVTKMKSPQDSPLGSRIASVHNGSSLFTGDAGSGESNIRRYIIENDMLDAIVQLPNNL  420

Query  421  FYNTGITTYIWLLNNNKPQDRQGKVQLIDASLLYRKLRKNLGNKNCEFAPEHIAEIAQTY  480
            FYNTGITTYIWLLNNNKP++RQGKVQLIDASLL+RKLRKNLGNKNCEF+PEHIAEI  TY
Sbjct  421  FYNTGITTYIWLLNNNKPENRQGKVQLIDASLLFRKLRKNLGNKNCEFSPEHIAEIVSTY  480

Query  481  LACAGVERKLDANHDAVGIASKVFSNDDFGYYKVTVERPDRRKARFTREAIQPLRFDKQL  540
            L   +VER +D + D+VGIA++VF N+DFGYYKV +ERPDRR+A+F  + I+PLRF++  
Sbjct  481  LENQSVERAIDEKGDPVGIAAQVFKNQDFGYYKVNIERPDRRNAQFRADLIEPLRFENSQ  540

Query  541  AEVMAWLYGEHGDKIYEKGFLASVEKATLAWCAERDISLNTKAKSKLLDVKNWLSLQRVY  600
             EVM  LY+E G+++Y+ GF+ ++EK    WC E DISLN  AK+KLLD KNW+  + + 
Sbjct  541  REVMEYLYAEYGEQVYDAGFVKGIEKEITKWCEENDISLNKAAKTKLLDTKNWMKQRTLV  600

Query  601  HTAERLMATLGGGEFDDFNLFKAQVEQVLKAEKIKLSAAEKNAIVNAVSWYDETAARVIN  660
            ++A +L   +G+  ++DFN FK  V+  L +  +KLSA+EK+AI++AVSWYDE A +VI+
Sbjct  601  NAASQLHKKIGDEVYNDFNQFKQLVDAELTSLGLKLSAPEKKAILDAVSWYDENAEKVIK  660

Query  661  KTVKLNGDKLQDLLARLECEAEDLPDFGFYPSGKKDEYIIYDSSADLRDTESVPLKQSIY  720
            K  KL+ DKL+DLL   ECE EDLPDFG+YP+G+ +E++ Y+SS+DLRD+ESVPL QSIY
Sbjct  661  KVAKLKQDKLDDLLENYECELEDLPDFGYYPTGNHNEFVTYESSSDLRDSESVPLEQSIY  720

Query  721  QYFLDEVKPHVAEAWINLDSVKIGYEISFNKYFYHPKPLRSLEEVAQDIIKLEQQSEGLI  780
            QYFLDEVKPHV EAW+NL+SVKIGYEISFNKYFY+ KPLRS++EVA++II LEQ++EGLI
Sbjct  721  QYFLDEVKPHVDEAWVNLESVKIGYEISFNKYFYRHKPLRSMDEVAKEIIALEQKAEGLI  780

Query  781  AQILGVSVDKIQG  793
            A+ILG+SV K+QG
Sbjct  781  ADILGISVAKVQG  793

18) EpC_35330 in NC_012214


> EU272902|18|G17|167832524|ACA01834.1|Vibrio_cholerae_Amazonia_3509|-|21794..24175|-|VPI2_0017c|DNA 
methylase HsdM
Length=793

 Score = 1029 bits (3901),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 596/793 (76%), Positives = 701/793 (89%), Gaps = 0/793 (0%)

Query  1    MDHSVHNKLISFIWNIADDCLRDVYVRGKYRDVILPMVVLRRLDTLLEPGKEAVLAEVKF  60
            MDHSVHNKL+SFIW+IADDCLRDVYVRGKYRDVILPMVVLRRLDTLLEP+KEAVL EV+F
Sbjct  1    MDHSVHNKLVSFIWSIADDCLRDVYVRGKYRDVILPMVVLRRLDTLLEPSKEAVLEEVRF  60

Query  61   QKEELRATELDDAPLMAASGYVFYNTSKWTLNLLFKAATNNQQILLANFEEYLLGFSDNV  120
            QKEE+   ELDDAPL A+SGYVFYNTSKWTL+ LF +ATNNQQILLANFE+YL GFS+NV
Sbjct  61   QKEEMNEIELDDAPLCATSGYVFYNTSKWTLQTLFSTATNNQQILLANFEDYLNGFSENV  120

Query  121  KEIVACFNLQAQIRHMASKQVLLDVVEKFVSPYINLTHKAVEDPEGYTMPALSNLGMGYV  180
            KEIV CFNL+AQIRHMA+K+VLLDVVEKFVSPYINLT    EDPEG  +PALSNLGMGYV
Sbjct  121  KEIVECFNLKAQIRHMAGKNVLLDVVEKFVSPYINLTPAVKEDPEGNKLPALSNLGMGYV  180

Query  181  FEELIRKFNEENNEEAGEHFTPREVIDLMTHLVFDPVKDKLPLTMTVYDPACGSGGMLTE  240
            FEELIRKFNEENNEEAGEHFTPREVI+LMTHLVFDP+KD+LPL++TVYDPACGSGGMLTE
Sbjct  181  FEELIRKFNEENNEEAGEHFTPREVIELMTHLVFDPIKDNLPLSITVYDPACGSGGMLTE  240

Query  241  SQNFIEAKYPSSNRDIYLYGKEINDETYAICKSDMMIKGNNPENIRVGSTLSTDEFAAER  300
            +QNF+E KYP+SNRDIYLYGKEINDETYAICKSDMMIKGNNPENIRVGSTLSTDEF+++R
Sbjct  241  TQNFVEEKYPASNRDIYLYGKEINDETYAICKSDMMIKGNNPENIRVGSTLSTDEFSSNR  300

Query  301  FDFMLSNPPYGKSWASEQKYIKDGGDVIDPRFKVRLQDYSGKEETVDATPRSSDGQLLFL  360
            FDFMLSNPPYGKSWASEQK IK+G +V+D RFKV+L+DY G E   +A PRSSDGQLLFL
Sbjct  301  FDFMLSNPPYGKSWASEQKHIKEGKEVVDGRFKVKLKDYWGVESEQEAIPRSSDGQLLFL  360

Query  361  MEMVSKMKDPAIGSLGSRIASVHNGSSLFTGDAGGGESNIRRYLIENDMLDAIVQLPNNL  420
            MEMV+KMK P  ++LGSRIASVHNGSSLFTGDAG+GESNIRRY+IENDMLDAIVQLPNNL
Sbjct  361  MEMVTKMKSPQDSPLGSRIASVHNGSSLFTGDAGSGESNIRRYIIENDMLDAIVQLPNNL  420

Query  421  FYNTGITTYIWLLNNNKPQDRQGKVQLIDASLLYRKLRKNLGNKNCEFAPEHIAEIAQTY  480
            FYNTGITTYIWLLNNNKP++RQGKVQLIDASLL+RKLRKNLGNKNCEF+PEHIAEI  TY
Sbjct  421  FYNTGITTYIWLLNNNKPENRQGKVQLIDASLLFRKLRKNLGNKNCEFSPEHIAEIVSTY  480

Query  481  LACAGVERKLDANHDAVGIASKVFSNDDFGYYKVTVERPDRRKARFTREAIQPLRFDKQL  540
            L   +VER +D + D+VGIA++VF N+DFGYYKV +ERPDRR+A+F  + I+PLRF++  
Sbjct  481  LENQSVERAIDEKGDPVGIAAQVFKNQDFGYYKVNIERPDRRNAQFRADLIEPLRFENSQ  540

Query  541  AEVMAWLYGEHGDKIYEKGFLASVEKATLAWCAERDISLNTKAKSKLLDVKNWLSLQRVY  600
             EVM  LY+E G+++Y+ GF+ ++EK    WC E DISLN  AK+KLLD KNW+  + + 
Sbjct  541  REVMEYLYAEYGEQVYDAGFVKGIEKEITKWCEENDISLNKAAKTKLLDTKNWMKQRTLV  600

Query  601  HTAERLMATLGGGEFDDFNLFKAQVEQVLKAEKIKLSAAEKNAIVNAVSWYDETAARVIN  660
            ++A +L   +G+  ++DFN FK  V+  L +  +KLSA+EK+AI++AVSWYDE A +VI+
Sbjct  601  NAASQLHKKIGDEVYNDFNQFKQLVDAELTSLGLKLSAPEKKAILDAVSWYDENAEKVIK  660

Query  661  KTVKLNGDKLQDLLARLECEAEDLPDFGFYPSGKKDEYIIYDSSADLRDTESVPLKQSIY  720
            K  KL+ DKL+DLL   ECE EDLPDFG+YP+G+ +E++ Y+SS+DLRD+ESVPL QSIY
Sbjct  661  KVAKLKQDKLDDLLENYECELEDLPDFGYYPTGNHNEFVTYESSSDLRDSESVPLEQSIY  720

Query  721  QYFLDEVKPHVAEAWINLDSVKIGYEISFNKYFYHPKPLRSLEEVAQDIIKLEQQSEGLI  780
            QYFLDEVKPHV EAW+NL+SVKIGYEISFNKYFY+ KPLRS++EVA++II LEQ++EGLI
Sbjct  721  QYFLDEVKPHVDEAWVNLESVKIGYEISFNKYFYRHKPLRSMDEVAKEIIALEQKAEGLI  780

Query  781  AQILGVSVDKIQG  793
            A+ILG+SV K+QG
Sbjct  781  ADILGISVAKVQG  793

19) Shewmr7_1782 in NC_008322


> EU272902|18|G17|167832524|ACA01834.1|Vibrio_cholerae_Amazonia_3509|-|21794..24175|-|VPI2_0017c|DNA 
methylase HsdM
Length=793

 Score = 1024 bits (3880),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 624/827 (76%), Positives = 712/827 (87%), Gaps = 34/827 (4%)

Query  1    MDHSVHNKLISFIWNIADDCLRDVYVRGKYRDVILPMVVLRRLDTLLEPTKEAVLEEVKF  60
            MDHSVHNKL+SFIW+IADDCLRDVYVRGKYRDVILPMVVLRRLDTLLEP+KEAVLEEV+F
Sbjct  1    MDHSVHNKLVSFIWSIADDCLRDVYVRGKYRDVILPMVVLRRLDTLLEPSKEAVLEEVRF  60

Query  61   QKEEMQATELDDEPLKAASGYVFYNTSKWTLKSLFNTATNNQQILLANFEEYLLGFSDNV  120
            QKEEM+  ELDD PL A+SGYVFYNTSKWTL++LF+TATNNQQILLANFE+YL GFS+NV
Sbjct  61   QKEEMNEIELDDAPLCATSGYVFYNTSKWTLQTLFSTATNNQQILLANFEDYLNGFSENV  120

Query  121  KEIIECFNLKSQIRHMASKQVLLDVVEKFVSPYINLTHETVEDPDGNKMPALTNLGMGYV  180
            KEI+ECFNLK+QIRHMA+K+VLLDVVEKFVSPYINLT    EDP+GNK+PAL+NLGMGYV
Sbjct  121  KEIVECFNLKAQIRHMAGKNVLLDVVEKFVSPYINLTPAVKEDPEGNKLPALSNLGMGYV  180

Query  181  FEELIRKFNEENNEEAGEHFTPREVIELMTHLVFDPVKDQLPLTMTVYDPACGSGGMLTE  240
            FEELIRKFNEENNEEAGEHFTPREVIELMTHLVFDP+KD+LPL++TVYDPACGSGGMLTE
Sbjct  181  FEELIRKFNEENNEEAGEHFTPREVIELMTHLVFDPIKDNLPLSITVYDPACGSGGMLTE  240

Query  241  SQNFIEEKYPNDPSVKTKRDVYLYGKEINDETYAICKSDMMIKGNNPENIKVGSTLSTDE  300
            +QNF+EEKYP      ++RD+YLYGKEINDETYAICKSDMMIKGNNPENI+VGSTLSTDE
Sbjct  241  TQNFVEEKYPA-----SNRDIYLYGKEINDETYAICKSDMMIKGNNPENIRVGSTLSTDE  295

Query  301  FAASRFDFMLSNPPYGKSWASEQKHIKDGSDVIDPRFKVSLKDYWGNLEVVDATPRSSDG  360
            F+++RFDFMLSNPPYGKSWASEQKHIK+G +V+D RFKV LKDYWG     +A PRSSDG
Sbjct  296  FSSNRFDFMLSNPPYGKSWASEQKHIKEGKEVVDGRFKVKLKDYWGVESEQEAIPRSSDG  355

Query  361  QLLFLMEMVNKMKDPSVSPLGSRIASVHNGSSLFTGDAGGGESNIRRFIIENDMLDAIVQ  420
            QLLFLMEMV KMK P  SPLGSRIASVHNGSSLFTGDAG+GESNIRR+IIENDMLDAIVQ
Sbjct  356  QLLFLMEMVTKMKSPQDSPLGSRIASVHNGSSLFTGDAGSGESNIRRYIIENDMLDAIVQ  415

Query  421  LPNNLFYNTGITTYIWVLNNNKPEARKGKVQLIDASLLYRKLRKNLGNKNCEFAPEHITE  480
            LPNNLFYNTGITTYIW+LNNNKPE R+GKVQLIDASLL+RKLRKNLGNKNCEF+PEHI+E
Sbjct  416  LPNNLFYNTGITTYIWLLNNNKPENRQGKVQLIDASLLFRKLRKNLGNKNCEFSPEHIAE  475

Query  481  ITDTYLACVDVERALDATAPEGMGDPVGIASKVFSNEDFGYYKVTIERPDRRRAKFTQEA  540
            I  TYL    VERA+D       GDPVGIA++VF N+DFGYYKV IERPDRR A+F  + 
Sbjct  476  IVSTYLENQSVERAIDEK-----GDPVGIAAQVFKNQDFGYYKVNIERPDRRNAQFRADL  530

Query  541  IAPLRFDKQLSEVMEYVYAEHGERVYEKTAPSNNKEGDEKKRSFLKSIEKDILSWCEEND  600
            I PLRF++   EVMEY+YAE GE+VY+               +F+K+IEK+I  WCEEND
Sbjct  531  IEPLRFENSQREVMEYLYAEYGEQVYDA--------------GFVKGIEKEITKWCEEND  576

Query  601  ISLNAKAKAKLLDVKHWlalkalletaetlmaDIGSIEFDDFNSFKTQVDKSLKTHAIKL  660
            ISLN  AK+KLLD K+W+  ++L+++A  L   IG   ++DFN FK  VD  L + ++KL
Sbjct  577  ISLNKAAKTKLLDTKNWMKQRTLVNAASQLHKKIGDEVYNDFNQFKQLVDAELTSLGLKL  636

Query  661  SAPEKNAILNVVSWYDESAkkvvkkvvkLTGDKLNDLLERYECEVADLPDFGYYPVPTTE  720
            SAPEK+AIL+ VSWYDE+A KV+KKV KL  DKL+DLLE YECE+ DLPDFGYYP     
Sbjct  637  SAPEKKAILDAVSWYDENAEKVIKKVAKLKQDKLDDLLENYECELEDLPDFGYYP-----  691

Query  721  GGKKNEFITYETNSDLRDTESVPLKQSIYQYFLDEVKPHVDEAWINLDTVKIGYEISFNK  780
             G+ NEF+TYE++SDLRD+ESVPL QSIYQYFLDEVKPHVDEAW+NL++VKIGYEISFNK
Sbjct  692  TGNHNEFVTYESSSDLRDSESVPLEQSIYQYFLDEVKPHVDEAWVNLESVKIGYEISFNK  751

Query  781  YFYRHKPLRSLIDVATDIINLEQKAEGLIAQILGIESLGVKVAEVQG  827
            YFYRHKPLRS+ +VA +II LEQKAEGLIA+ILGI      VA VQG
Sbjct  752  YFYRHKPLRSMDEVAKEIIALEQKAEGLIADILGI-----SVAKVQG  793

20) CYCME_2465 in NC_021917


> EU272902|18|G17|167832524|ACA01834.1|Vibrio_cholerae_Amazonia_3509|-|21794..24175|-|VPI2_0017c|DNA 
methylase HsdM
Length=793

 Score = 1021 bits (3869),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 606/805 (76%), Positives = 710/805 (89%), Gaps = 12/805 (1%)

Query  1    MDHSVHNKLVSFIWNIADDCLRDVYVRGKYRDVILPMVVLRRLDTLLEPSKQAVLDEVKF  60
            MDHSVHNKLVSFIW+IADDCLRDVYVRGKYRDVILPMVVLRRLDTLLEPSK+AVL+EV+F
Sbjct  1    MDHSVHNKLVSFIWSIADDCLRDVYVRGKYRDVILPMVVLRRLDTLLEPSKEAVLEEVRF  60

Query  61   QKEDMNATELDDEPLKAASGQVFYNVSKWTLKSLFSTATNNQQILLANFEEYLNGFSDNV  120
            QKE+MN  ELDD PL A+SG VFYN SKWTL++LFSTATNNQQILLANFE+YLNGFS+NV
Sbjct  61   QKEEMNEIELDDAPLCATSGYVFYNTSKWTLQTLFSTATNNQQILLANFEDYLNGFSENV  120

Query  121  KEIIERFELLSKIRHMAGKDVLLDVLEKFVSPHINLTPNQVEDPDGNKLPALTNLGMGYV  180
            KEI+E F+L ++IRHMAGK+VLLDV+EKFVSP INLTP   EDP+GNKLPAL+NLGMGYV
Sbjct  121  KEIVECFNLKAQIRHMAGKNVLLDVVEKFVSPYINLTPAVKEDPEGNKLPALSNLGMGYV  180

Query  181  FEELIRKFNEENNEEAGEHFTPREVIELMTHLVFDPIKDDLPLTMSVYDPACGSGGMLTE  240
            FEELIRKFNEENNEEAGEHFTPREVIELMTHLVFDPIKD+LPL+++VYDPACGSGGMLTE
Sbjct  181  FEELIRKFNEENNEEAGEHFTPREVIELMTHLVFDPIKDNLPLSITVYDPACGSGGMLTE  240

Query  241  SQNFIEEKYPASASSQVQRDIYLYGKEINDETYAICKSDMMIKGNNPENIKVGSTLSTDE  300
            +QNF+EEKYPAS     +RDIYLYGKEINDETYAICKSDMMIKGNNPENI+VGSTLSTDE
Sbjct  241  TQNFVEEKYPAS-----NRDIYLYGKEINDETYAICKSDMMIKGNNPENIRVGSTLSTDE  295

Query  301  FASDRFDFMLSNPPYGKSWASEQKNIKDGGEVIDPRFKVELTDYWGNKETADATPRSSDG  360
            F+S+RFDFMLSNPPYGKSWASEQK+IK+G EV+D RFKV L DYWG     +A PRSSDG
Sbjct  296  FSSNRFDFMLSNPPYGKSWASEQKHIKEGKEVVDGRFKVKLKDYWGVESEQEAIPRSSDG  355

Query  361  QLLFLMEMVSKMKSPSTSPMGTRIASVHNGSSLFTGDAGGGESNIRRFIIENDMLDAIVQ  420
            QLLFLMEMV+KMKSP  SP+G+RIASVHNGSSLFTGDAG+GESNIRR+IIENDMLDAIVQ
Sbjct  356  QLLFLMEMVTKMKSPQDSPLGSRIASVHNGSSLFTGDAGSGESNIRRYIIENDMLDAIVQ  415

Query  421  LPNNLFYNTGITTYIWLLNNNKPEARRGKIQLIDASLLFRKLRKNLGNKNCEFAPEHIAE  480
            LPNNLFYNTGITTYIWLLNNNKPE R+GK+QLIDASLLFRKLRKNLGNKNCEF+PEHIAE
Sbjct  416  LPNNLFYNTGITTYIWLLNNNKPENRQGKVQLIDASLLFRKLRKNLGNKNCEFSPEHIAE  475

Query  481  ITQAYLDCADIERTLDANNDAVGIASQVFKNEDFGYHKVNIERPDRRKAKFTPEAIAPLR  540
            I  +YL+   +ER++D + D+VGIA+QVFKN+DFGY KVNIERPDRR+A+F ++ I PLR
Sbjct  476  IVSTYLENQSVERAIDEKGDPVGIAAQVFKNQDFGYYKVNIERPDRRNAQFRADLIEPLR  535

Query  541  FDKSLLEVMEHLFEEHDDKVYDQGFLKGISKDILEWCEDNDISVNAKAKSKLLDEKYWQK  600
            F++S  EVME L+ E +++VYD GF+KGI K+I  WCE+NDIS+N  AK+KLLD K W K
Sbjct  536  FENSQREVMEYLYAEYGEQVYDAGFVKGIEKEITKWCEENDISLNKAAKTKLLDTKNWMK  595

Query  601  LRAILEAANLLMQEIGSDEFKDFNLFKVKVDAVLKEQKIKLSAPEKNAILNAVSWYDEHA  660
             R++++AA+ L + IG + ++DFN FK  VDA L    +KLSAPEK+AIL+AVSWYDE+A
Sbjct  596  QRTLVNAASQLHKKIGDEVYNDFNQFKQLVDAELTSLGLKLSAPEKKAILDAVSWYDENA  655

Query  661  EkvvkkvvkLSDTKLEELLNHLGCSQNQLADFGYYSTSACGDDKNSAGEYIIYEPNSDLR  720
            EKV+KKV KL + KL++LL++  C  ++L+DFGYY+T+       +  E++ YE++SDLR
Sbjct  656  EKVIKKVAKLKQDKLDDLLENYECELEDLPDFGYYPTG-------NHNEFVTYESSSDLR  708

Query  721  DSESVPLAQEIHDYFLEEVKPHVEEAWINLDSTKIGYEISFNKYFYRHKPLRELSEVAND  780
            DSESVPL Q I +YFL+EVKPHV+EAW+NL+S KIGYEISFNKYFYRHKPLR + EVA++
Sbjct  709  DSESVPLEQSIYQYFLDEVKPHVDEAWVNLESVKIGYEISFNKYFYRHKPLRSMDEVAKE  768

Query  781  IIDLEQKAEGLIAQILGVDVAEIQG  805
            II LEQKAEGLIA+ILG+ VA +QG
Sbjct  769  IIALEQKAEGLIADILGISVAKVQG  793

21) HP15_1578 in NC_017506


> EU272902|18|G17|167832524|ACA01834.1|Vibrio_cholerae_Amazonia_3509|-|21794..24175|-|VPI2_0017c|DNA 
methylase HsdM
Length=793

 Score = 1011 bits (3832),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 599/807 (75%), Positives = 708/807 (88%), Gaps = 14/807 (1%)

Query  1    MDHSAHNKLVSFIWNIADDCLRDVYVRGKYRDVILPMVVLRRLDTLLMPTKEAVLEEVRF  60
            MDHS HNKLVSFIW+IADDCLRDVYVRGKYRDVILPMVVLRRLDTLL P+KEAVLEEVRF
Sbjct  1    MDHSVHNKLVSFIWSIADDCLRDVYVRGKYRDVILPMVVLRRLDTLLEPSKEAVLEEVRF  60

Query  61   QKEEMDATELDPAPLKAASGYVFYNVSKWTLTSLYNTATNNRQILLANFEEYLKGFSPNV  120
            QKEEM+  ELD APL A+SGYVFYN SKWTL +L++TATNN+QILLANFE+YL+GFS NV
Sbjct  61   QKEEMNEIELDDAPLCATSGYVFYNTSKWTLQTLFSTATNNQQILLANFEDYLNGFSENV  120

Query  121  QEIIECFELKSKIQHMAHKDVLLDVVEKFVSPKINLTPKDALDPDGYKLPGLSNLGMGYV  180
            +EI+ECF+LK++I+HMA K+VLLDVVEKFVSP INLTP    DP+G KLP+LSNLGMGYV
Sbjct  121  KEIVECFNLKAQIRHMAGKNVLLDVVEKFVSPYINLTPAVKEDPEGNKLPALSNLGMGYV  180

Query  181  FEELIRKFNEENNEEAGEHFTPREVIELMTHLVFDPIKDDLPLTLTVYDPACGSGGMLTE  240
            FEELIRKFNEENNEEAGEHFTPREVIELMTHLVFDPIKD+LPL++TVYDPACGSGGMLTE
Sbjct  181  FEELIRKFNEENNEEAGEHFTPREVIELMTHLVFDPIKDNLPLSITVYDPACGSGGMLTE  240

Query  241  SQNFIEEKYPSDNRDIYLYGKEINDETYAICKSDMMIKGNNPENIKVGSTLSTDEFASDR  300
            +QNF+EEKYP+ NRDIYLYGKEINDETYAICKSDMMIKGNNPENI+VGSTLSTDEF+S+R
Sbjct  241  TQNFVEEKYPASNRDIYLYGKEINDETYAICKSDMMIKGNNPENIRVGSTLSTDEFSSNR  300

Query  301  FDFMLSNPPYGKSWASEQKHIKDGSDVIDPRFKIQLKDYWGNEEDCDATPRSSDGQLLFL  360
            FDFMLSNPPYGKSWASEQKHIK+G +V+D RFK++LKDYWG E + +A PRSSDGQLLFL
Sbjct  301  FDFMLSNPPYGKSWASEQKHIKEGKEVVDGRFKVKLKDYWGVESEQEAIPRSSDGQLLFL  360

Query  361  MEMVSKMKDPATGSKGSRIASVHNGSSLFTGDAGGGESNIRRYLIENDWLEAIVQLPNNL  420
            MEMV+KMK P  ++ GSRIASVHNGSSLFTGDAG+GESNIRRY+IEND L+AIVQLPNNL
Sbjct  361  MEMVTKMKSPQDSPLGSRIASVHNGSSLFTGDAGSGESNIRRYIIENDMLDAIVQLPNNL  420

Query  421  FYNTGITTYIWVLNNNKPANRRGKVQLIDASLLYRKLRKNLGNKNCEFAPDHIEQITRTY  480
            FYNTGITTYIW+LNNNKP NR+GKVQLIDASLL+RKLRKNLGNKNCEF+P+HI +I  TY
Sbjct  421  FYNTGITTYIWLLNNNKPENRQGKVQLIDASLLFRKLRKNLGNKNCEFSPEHIAEIVSTY  480

Query  481  LDCTAIERELDANNDPVGIASQVFRNEDFGYHKVTIERPDRRKAQFSEERIAGLRFDKQI  540
            L+  ++ER +D + DPVGIA+QVF+N+DFGY KV IERPDRR+AQF  + I  LRF++  
Sbjct  481  LENQSVERAIDEKGDPVGIAAQVFKNQDFGYYKVNIERPDRRNAQFRADLIEPLRFENSQ  540

Query  541  SEVMEHLYAEHGDKVYDSTGHGKDNKQSFLKSIEKPVMAWCDDNDISLNTKAKTKLLDVK  600
             EVME LYAE G++VYD+         +F+K+IEK +  WC++NDISLN  AKTKLLD K
Sbjct  541  REVMEYLYAEYGEQVYDA---------GFVKGIEKEITKWCEENDISLNKAAKTKLLDTK  591

Query  601  RWASLKAIYETARELMAAIGQDEFDDFNQFKKQVDTELKARKLKLSATEKNAILNAISWY  660
             W   +++ ++A +L   IG++ ++DFNQFK+ VD+EL +  LKLSA EK+AIL+A+SWY
Sbjct  592  NWMKQRTLVNAASQLHKKIGDEVYNDFNQFKQLVDAELTSLGLKLSAPEKKAILDAVSWY  651

Query  661  DETAEkvvkkvvkLNGDKLDELLHRYDCSAEQLPDYGLYPTGKANEYITFESSSDLRDSE  720
            DE AEKV+KKV KL+ DKLD+LL+ Y+C  E+LPD+G YPTG+ NE++T+ESSSDLRDSE
Sbjct  652  DENAEKVIKKVAKLKQDKLDDLLENYECELEDLPDFGYYPTGNHNEFVTYESSSDLRDSE  711

Query  721  SIALLKDGEKQGIHGYFLAEVKPHVEEAWINLDSTKIGYEISFNKYFYRHKPLRSLEEVA  780
            S++L      Q+I  YFL EVKPHV+EAW+NL+S KIGYEISFNKYFYRHKPLRS++EVA
Sbjct  712  SVPL-----EQSIYQYFLDEVKPHVDEAWVNLESVKIGYEISFNKYFYRHKPLRSMDEVA  766

Query  781  QDIISLEQKAEGLIAQILGVDVEQVQG  807
            ++II+LEQKAEGLIA+ILG+ V +VQG
Sbjct  767  KEIIALEQKAEGLIADILGISVAKVQG  793

22) Tola_2273 in NC_012691


> EU272902|18|G17|167832524|ACA01834.1|Vibrio_cholerae_Amazonia_3509|-|21794..24175|-|VPI2_0017c|DNA 
methylase HsdM
Length=793

 Score = 1010 bits (3827),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 608/792 (77%), Positives = 701/792 (89%), Gaps = 4/792 (0%)

Query  1    MDHSVHNKLVSFIWSIADDCLRDVYVRGKYRDVILPMVVLRRLDTLLEPSKEAVLEEVRF  60
            MDHSVHNKLVSFIWSIADDCLRDVYVRGKYRDVILPMVVLRRLDTLLEPSKEAVLEEVRF
Sbjct  1    MDHSVHNKLVSFIWSIADDCLRDVYVRGKYRDVILPMVVLRRLDTLLEPSKEAVLEEVRF  60

Query  61   QQEEMNAVELDDEPLKAASGYVFYNISKWTLKTLHAAATNNQQILLQNFNEYLNGFSDNV  120
            Q+EEMN +ELDD PL A+SGYVFYN SKWTL+TL ++ATNNQQILL NF++YLNGFS+NV
Sbjct  61   QKEEMNEIELDDAPLCATSGYVFYNTSKWTLQTLFSTATNNQQILLANFEDYLNGFSENV  120

Query  121  KEIVGRFNLKSQIRHMAEKQVLLDVVEKFISPNINLTPQECEDASGNKLPALTNLGMGYV  180
            KEIV  FNLK+QIRHMA K+VLLDVVEKF+SP INLTP   ED+ GNKLPAL+NLGMGYV
Sbjct  121  KEIVECFNLKAQIRHMAGKNVLLDVVEKFVSPYINLTPAVKEDPEGNKLPALSNLGMGYV  180

Query  181  FEELIRKFNEENNEEAGEHFTPREVIELMTHLVFDPLKDQLPLTMTIYDPACGSGGMLTE  240
            FEELIRKFNEENNEEAGEHFTPREVIELMTHLVFDP+KD+LPL++T+YDPACGSGGMLTE
Sbjct  181  FEELIRKFNEENNEEAGEHFTPREVIELMTHLVFDPIKDNLPLSITVYDPACGSGGMLTE  240

Query  241  SQNFIEEKYPAVGASRDIHLYGKEINDETYAICKSDMMIKGNDPANIKIGSTLSTDEFSH  300
            +QNF+EEKYPA  ++RDI LYGKEINDETYAICKSDMMIKGN+P NI++GSTLSTDEFS 
Sbjct  241  TQNFVEEKYPA--SNRDIYLYGKEINDETYAICKSDMMIKGNNPENIRVGSTLSTDEFSS  298

Query  301  MRFDFMLSNPPYGKSWASEQKNIKEGTEVIDPRFKVQLTDYWGKVDAKGSDATPRSSDGQ  360
             RFDFMLSNPPYGKSWASEQK+IKEG EV+D RFKV+L DYWG V++   +A PRSSDGQ
Sbjct  299  NRFDFMLSNPPYGKSWASEQKHIKEGKEVVDGRFKVKLKDYWG-VES-EQEAIPRSSDGQ  356

Query  361  LLFLMEMVSKMKAPVNGTIGSRIASVHNGSSLFTGDAGGGESNIRRYLIENDMLEAIVQL  420
            LLFLMEMV+KMK+P ++ +GSRIASVHNGSSLFTGDAG+GESNIRRY+IENDML+AIVQL
Sbjct  357  LLFLMEMVTKMKSPQDSPLGSRIASVHNGSSLFTGDAGSGESNIRRYIIENDMLDAIVQL  416

Query  421  PNNLFYNTGITTYIWLLNNNKPERRKGKVQLIDASQLFRKLRKNLGNKNCEFAPEHIAEI  480
            PNNLFYNTGITTYIWLLNNNKPE R+GKVQLIDAS LFRKLRKNLGNKNCEF+PEHIAEI
Sbjct  417  PNNLFYNTGITTYIWLLNNNKPENRQGKVQLIDASLLFRKLRKNLGNKNCEFSPEHIAEI  476

Query  481  MQTYLEFNEVERQLDANGDAIGLASKIFNNEDFGYFKVTVERPDRRKAQFSAERIAPLRF  540
            + TYLE + VER +D +GD++G+A+++F+N+DFGY+KV +ERPDRR+AQF A+ I PLRF
Sbjct  477  VSTYLENQSVERAIDEKGDPVGIAAQVFKNQDFGYYKVNIERPDRRNAQFRADLIEPLRF  536

Query  541  DKSLSEAMEYCYGEYNDKVYQAGFLAEQGKHITDWCEKNDISLNNKAKEKLLDTAFWLSS  600
            ++S  E MEY Y+EY ++VY+AGF+    K+IT WCE NDISLN+ AK KLLDT  W+  
Sbjct  537  ENSQREVMEYLYAEYGEQVYDAGFVKGIEKEITKWCEENDISLNKAAKTKLLDTKNWMKQ  596

Query  601  RKLLDAAQTLMEGVGEAEFTDFNLFKDKVDaalkasslklsaPEKNAILNAVSWYDETAE  660
            R L++AA  L   +G+  + DFN FK+ VDA L + +LKLSAPEK+AIL+AVSWYDE AE
Sbjct  597  RTLVNAASQLHKKIGDEVYNDFNQFKQLVDAELTSLGLKLSAPEKKAILDAVSWYDENAE  656

Query  661  KVVKKVLKLSADKLAELLELYSCEEGDLPDFGYYPHGKKGEFVTYESSSDLRDTESVPLK  720
            KV+KKV KL  DKL +LLE Y CE  DLPDFGYYP G+  EFVTYESSSDLRD+ESVPL 
Sbjct  657  KVIKKVAKLKQDKLDDLLENYECELEDLPDFGYYPTGNHNEFVTYESSSDLRDSESVPLE  716

Query  721  QSIYQYFLDEVKPHVAEAWLNMESVKIGCEISFNKYFYRHKPLRKLEAVAQEIIDLEKQA  780
            QSIYQYFLDEVKPHV EAW+N+ESVKIG EISFNKYFYRHKPLR ++ VA+EII LE++A
Sbjct  717  QSIYQYFLDEVKPHVDEAWVNLESVKIGYEISFNKYFYRHKPLRSMDEVAKEIIALEQKA  776

Query  781  DGLIAQILGLTT  792
            +GLIA+ILG++ 
Sbjct  777  EGLIADILGISV  788

23) NT01EI_2505 in NC_012779


> EU272902|18|G17|167832524|ACA01834.1|Vibrio_cholerae_Amazonia_3509|-|21794..24175|-|VPI2_0017c|DNA 
methylase HsdM
Length=793

 Score = 1008 bits (3820),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 602/802 (76%), Positives = 703/802 (88%), Gaps = 9/802 (1%)

Query  1    MDHSVHNKLVSFIWNIADDCLRDVYVRGKYRDVILPMVVLRRLDTLLEPTKEAVLEEVRF  60
            MDHSVHNKLVSFIW+IADDCLRDVYVRGKYRDVILPMVVLRRLDTLLEP+KEAVLEEVRF
Sbjct  1    MDHSVHNKLVSFIWSIADDCLRDVYVRGKYRDVILPMVVLRRLDTLLEPSKEAVLEEVRF  60

Query  61   QQQEMNAVELDEEPLKAASGYVFYNISKWTLKSLLNAATNNQQILLANVNEYLNGFSDNV  120
            Q++EMN +ELD+ PL A+SGYVFYN SKWTL++L+++ATNNQQILLAN ++YLNGFS+NV
Sbjct  61   QKEEMNEIELDDAPLCATSGYVFYNTSKWTLQTLFSTATNNQQILLANFEDYLNGFSENV  120

Query  121  TEIVNCFNLRAQIRHMADKQVLLDVIEKFVSPYINLTPNDIEDPEGNKLPALTNLGMGYV  180
             EIV+CFNL+AQIRHMA+K+VLLDV+EKFVSPYINLTP   EDPEGNKLPAL+NLGMGYV
Sbjct  121  KEIVECFNLKAQIRHMAGKNVLLDVVEKFVSPYINLTPAVKEDPEGNKLPALSNLGMGYV  180

Query  181  FEELIRKFNEENNEEAGEHFTPREVIELMTHLVFDPIKDQLPLTMTIYDPACGSGGMLTE  240
            FEELIRKFNEENNEEAGEHFTPREVIELMTHLVFDPIKD+LPL++T+YDPACGSGGMLTE
Sbjct  181  FEELIRKFNEENNEEAGEHFTPREVIELMTHLVFDPIKDNLPLSITVYDPACGSGGMLTE  240

Query  241  SQGFIAEKYPATGVSRDIYLYGKEINDETYAICKSDMMIRGNDPANIKVGSTLSTDEFSH  300
            +Q F+ EKYPA+  +RDIYLYGKEINDETYAICKSDMMI+GN+P NI+VGSTLSTDEFS 
Sbjct  241  TQNFVEEKYPAS--NRDIYLYGKEINDETYAICKSDMMIKGNNPENIRVGSTLSTDEFSS  298

Query  301  MRFDFMLSNPPYGKSWASEQKHIKDGNEVIDSRFKVKLADYWGVVAPKDCDATPRSSDGQ  360
             RFDFMLSNPPYGKSWASEQKHIK+G+EV+D+RFKVKL DYWGV + ++  A PRSSDGQ
Sbjct  299  NRFDFMLSNPPYGKSWASEQKHIKEGKEVVDGRFKVKLKDYWGVESEQE--AIPRSSDGQ  356

Query  361  LLFLMEMVNKMKSPSVSPLGSRIASVHNGSSLFTGDAGSGESNIRRYLIENDMLEAIVQL  420
            LLFLMEMV KMKSP  SPLGSRIASVHNGSSLFTGDAGSGESNIRRY+IENDML+AIVQL
Sbjct  357  LLFLMEMVTKMKSPQDSPLGSRIASVHNGSSLFTGDAGSGESNIRRYIIENDMLDAIVQL  416

Query  421  PNNLFYNTGITTYIWLLNNHKPASRQGKVQLIDASLLYRKLRKNLGEKNCELSPEHIEEI  480
            PNNLFYNTGITTYIWLLNN+KP +RQGKVQLIDASLL+RKLRKNLG+KNCE+SPEHI EI
Sbjct  417  PNNLFYNTGITTYIWLLNNNKPENRQGKVQLIDASLLFRKLRKNLGNKNCEFSPEHIAEI  476

Query  481  TQTCLACANVERQLDSNNDPVGIASKVFKNEDFGYYKVTVERPDRRKAQFSSERLNALRF  540
              T L   +VER +D + DPVGIA++VFKN+DFGYYKV +ERPDRR+AQF ++ +++LRF
Sbjct  477  VSTYLENQSVERAIDEKGDPVGIAAQVFKNQDFGYYKVNIERPDRRNAQFRADLIEPLRF  536

Query  541  DKSLHEVMAHCFAEYGEQVYQEGGLTRHSKPILEWCEKNEISLNNKAKEKLQSSTFWCAA  600
            ++S +EVM   +AEYGEQVY+ G +    K I  WCE N+ISLN+ AK KL  +  W   
Sbjct  537  ENSQREVMEYLYAEYGEQVYDAGFVKGIEKEITKWCEENDISLNKAAKTKLLDTKNWMKQ  596

Query  601  RTLFDTAHTLMREIGEAEFNDFNRFKAQVEATLKAQKLKLSVTEKNALFNAVSWYDETAA  660
            RTL ++A  L + IG+  +NDFN+FK  V+A L +  LKLS  EK+A+++AVSWYDE A 
Sbjct  597  RTLVNAASQLHKKIGDEVYNDFNQFKQLVDAELTSLGLKLSAPEKKAILDAVSWYDENAE  656

Query  661  kvvkkvvkLSADKLGELLELYSCEEADLPDFGYYPYPPEQGGKKGEFVTYESSSDLRDSE  720
            KV+KKV KL  DKL++LLE Y CE  DLPDFGYYP      G+  EFVTYESSSDLRDSE
Sbjct  657  KVIKKVAKLKQDKLDDLLENYECELEDLPDFGYYP-----TGNHNEFVTYESSSDLRDSE  711

Query  721  SVPLTQSIYQYFLDEVKPHVAEAWLNMESVKIGYEVSFNKYFYRHKSLRSLETVAQEILT  780
            SVPL QSIYQYFLDEVKPHV EAW+N+ESVKIGYE+SFNKYFYRHK+LRS++ VA+EI++
Sbjct  712  SVPLEQSIYQYFLDEVKPHVDEAWVNLESVKIGYEISFNKYFYRHKPLRSMDEVAKEIIA  771

Query  781  LEQQADGLIAQILGLTAPNTQA  802
            LEQ+A+GLIA+ILG++ ++ Q+
Sbjct  772  LEQKAEGLIADILGISVAKVQG  793

24) CGSHiGG_03080 in NC_009567


> EU272902|18|G17|167832524|ACA01834.1|Vibrio_cholerae_Amazonia_3509|-|21794..24175|-|VPI2_0017c|DNA 
methylase HsdM
Length=793

 Score =  977 bits (3701),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 555/788 (71%), Positives = 677/788 (86%), Gaps = 4/788 (0%)

Query  1    MDHSVHNKLVSFIWSIADDCLRDVYVRGKYRDVILPMFVLRRLDTLLEPSKDAVLEEMRF  60
            MDHSVHNKLVSFIWSIADDCLRDVYVRGKYRDVILPM VLRRLDTLLEPSK+AVLEE+RF
Sbjct  1    MDHSVHNKLVSFIWSIADDCLRDVYVRGKYRDVILPMVVLRRLDTLLEPSKEAVLEEVRF  60

Query  61   QKEELAFTELDDLPLKKITGHVFYNTSKWTLKSLYQTASNTPQYMLANFEEYLDGFSTNV  120
            QKEE+   ELDD PL   +G VFYNTSKWTL++L+ TA+N  Q +LANFE+YL+GFS NV
Sbjct  61   QKEEMNEIELDDAPLCATSGYVFYNTSKWTLQTLFSTATNNQQILLANFEDYLNGFSENV  120

Query  121  HEIINCFKLREQIRHMSHKNVLLSVLEKFVSPYINLTPKEQQDPEGNKLPALTNLGMGYV  180
             EI++CF+L+ QIRHM+ KNVLL V+EKFVSPYINLTP  ++DPEGNKLPAL+NLGMGYV
Sbjct  121  KEIVECFNLKAQIRHMAGKNVLLDVVEKFVSPYINLTPAVKEDPEGNKLPALSNLGMGYV  180

Query  181  FEELIRKFNEENNEEAGEHFTPREVIELMTHLVFDPLKDQIPAIITIYDPACGSGGMLTE  240
            FEELIRKFNEENNEEAGEHFTPREVIELMTHLVFDP+KD++P  IT+YDPACGSGGMLTE
Sbjct  181  FEELIRKFNEENNEEAGEHFTPREVIELMTHLVFDPIKDNLPLSITVYDPACGSGGMLTE  240

Query  241  SQNFIEQKYPLSESQGERSIFLFGKETNDETYAICKSDMMIKGDNPENIKVGSTLATDSF  300
            +QNF+E+KYP     ++R I+L+GKE NDETYAICKSDMMIKG+NPENI+VGSTL+TD F
Sbjct  241  TQNFVEEKYP----ASNRDIYLYGKEINDETYAICKSDMMIKGNNPENIRVGSTLSTDEF  296

Query  301  QGNHFDFMLSNPPYGKSWSKDQAYIKDGNEVIDSRFKVTLPDYWGNEETLDATPRSSDGQ  360
             +N+FDFMLSNPPYGKSW+ +Q  IK+G+EV+D+RFKV L DYWG E   +A PRSSDGQ
Sbjct  297  SSNRFDFMLSNPPYGKSWASEQKHIKEGKEVVDGRFKVKLKDYWGVESEQEAIPRSSDGQ  356

Query  361  LLFLMEMVNKMKSPKNNKIGSRVASVHNGSSLFTGDAGSGESNIRRHIIENDLLEAIVQL  420
            LLFLMEMV KMKSP+++ +GSR+ASVHNGSSLFTGDAGSGESNIRR IIEND+L+AIVQL
Sbjct  357  LLFLMEMVTKMKSPQDSPLGSRIASVHNGSSLFTGDAGSGESNIRRYIIENDMLDAIVQL  416

Query  421  PNNLFYNTGITTYIWLLSNNKPEARKGKVQLIDASLLFRKLRKNLGDKNCEFAPEHIAEI  480
            PNNLFYNTGITTYIWLL+NNKPE R+GKVQLIDASLLFRKLRKNLG+KNCEF+PEHIAEI
Sbjct  417  PNNLFYNTGITTYIWLLNNNKPENRQGKVQLIDASLLFRKLRKNLGNKNCEFSPEHIAEI  476

Query  481  TQNYLDFTAKARETDSQNEAVGLASQIFDNQDFGYYKVTIERPDRRSAQFTAENIAPLRF  540
               YL+  +  R  D + ++VG+A+Q+F NQDFGYYKV IERPDRR+AQF A+ I PLRF
Sbjct  477  VSTYLENQSVERAIDEKGDPVGIAAQVFKNQDFGYYKVNIERPDRRNAQFRADLIEPLRF  536

Query  541  DKALFEPMQYLYQQHGEQIYNAGFLAKTEPEISTWCEAQGIALNNKNKAKLLDVKTWEKA  600
            +++  E M+YLY + GEQ+Y+AGF+   E EI+ WCE ++I+LN+  K+KLLD K W K 
Sbjct  537  ENSQREVMEYLYAEYGEQVYDAGFVKGIEKEITKWCEENDISLNKAAKTKLLDTKNWMKQ  596

Query  601  AALFQTASKLLEHFGSTQFDDFNQFKQAVEGRLKAEKIPLSATEKKAIFNAVSWYDENAA  660
             +L ++AS+L   +G   ++DFNQFKQ V++ L +  + LSA EKKAI++AVSWYDENA 
Sbjct  597  RTLVNAASQLHKKIGDEVYNDFNQFKQLVDAELTSLGLKLSAPEKKAILDAVSWYDENAE  656

Query  661  KVIAKTLKLKPNELDALCQRYQCQADELADFGYYATGKAGEYIQYETSSDLRDSESIPLK  720
            KVI K  KLK + LD L + Y+C+ ++L+DFGYY+TG+  E++ YE+SSDLRDSES+PL 
Sbjct  657  KVIKKVAKLKQDKLDDLLENYECELEDLPDFGYYPTGNHNEFVTYESSSDLRDSESVPLE  716

Query  721  QNIHDYFKAEVQPHISEAWLNMESVKIGYEISFNKYFYRHKSLRSLEEVTQDILALEKQA  780
            Q+I +YF  EV+PH+ EAW+N+ESVKIGYEISFNKYFYRHK+LRS++EV+++I+ALE++A
Sbjct  717  QSIYQYFLDEVKPHVDEAWVNLESVKIGYEISFNKYFYRHKPLRSMDEVAKEIIALEQKA  776

Query  781  DGLISEIL  788
            +GLI++IL
Sbjct  777  EGLIADIL  784

25) hsdM1 in NC_007146


> EU272902|18|G17|167832524|ACA01834.1|Vibrio_cholerae_Amazonia_3509|-|21794..24175|-|VPI2_0017c|DNA 
methylase HsdM
Length=793

 Score =  975 bits (3696),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 554/788 (71%), Positives = 677/788 (86%), Gaps = 4/788 (0%)

Query  1    MEHSVHNKLVSFIWSIADDCLRDVYVRGKYRDVILPMFVLRRLDTLLEPSKDAVLEEMRF  60
            M+HSVHNKLVSFIWSIADDCLRDVYVRGKYRDVILPM VLRRLDTLLEPSK+AVLEE+RF
Sbjct  1    MDHSVHNKLVSFIWSIADDCLRDVYVRGKYRDVILPMVVLRRLDTLLEPSKEAVLEEVRF  60

Query  61   QKEELAFTELDDLPLKKITGHVFYNTSKWTLKSLYQTASNTPQYMLANFEEYLDGFSTNI  120
            QKEE+   ELDD PL   +G VFYNTSKWTL++L+ TA+N  Q +LANFE+YL+GFS N+
Sbjct  61   QKEEMNEIELDDAPLCATSGYVFYNTSKWTLQTLFSTATNNQQILLANFEDYLNGFSENV  120

Query  121  HEIINCFKLREQIRHMSHKNVLLSVLEKFVSPYINLTPKEQQDPEGNKLPALTNLGMGYV  180
             EI++CF+L+ QIRHM+ KNVLL V+EKFVSPYINLTP  ++DPEGNKLPAL+NLGMGYV
Sbjct  121  KEIVECFNLKAQIRHMAGKNVLLDVVEKFVSPYINLTPAVKEDPEGNKLPALSNLGMGYV  180

Query  181  FEELIRKFNEENNEEAGEHFTPREVIELMTHLVFDPLKDQIPAIITIYDPACGSGGMLTE  240
            FEELIRKFNEENNEEAGEHFTPREVIELMTHLVFDP+KD++P  IT+YDPACGSGGMLTE
Sbjct  181  FEELIRKFNEENNEEAGEHFTPREVIELMTHLVFDPIKDNLPLSITVYDPACGSGGMLTE  240

Query  241  SQNFIEQKYPLSESQGERSIFLFGKETNDETYAICKSDMMIKGDNPENIKVGSTLATDSF  300
            +QNF+E+KYP     ++R I+L+GKE NDETYAICKSDMMIKG+NPENI+VGSTL+TD F
Sbjct  241  TQNFVEEKYP----ASNRDIYLYGKEINDETYAICKSDMMIKGNNPENIRVGSTLSTDEF  296

Query  301  QGNHFDFMLSNPPYGKSWSKDQAYIKDGNEVIDSRFKVTLPDYWGNVETLDATPRSSDGQ  360
             +N+FDFMLSNPPYGKSW+ +Q  IK+G+EV+D+RFKV L DYWG     +A PRSSDGQ
Sbjct  297  SSNRFDFMLSNPPYGKSWASEQKHIKEGKEVVDGRFKVKLKDYWGVESEQEAIPRSSDGQ  356

Query  361  LLFLMEMVSKMKSPNDNKIGSRVASVHNGSSLFTGDAGSGESNIRRHIIEKDLLEAIVQL  420
            LLFLMEMV+KMKSP+D+ +GSR+ASVHNGSSLFTGDAGSGESNIRR IIE+D+L+AIVQL
Sbjct  357  LLFLMEMVTKMKSPQDSPLGSRIASVHNGSSLFTGDAGSGESNIRRYIIENDMLDAIVQL  416

Query  421  PNNLFYNTGITTYIWLLSNNKPEARKGKVQLIDASLLFRKLRKNLGDKNCEFVPEHIAEI  480
            PNNLFYNTGITTYIWLL+NNKPE R+GKVQLIDASLLFRKLRKNLG+KNCEF PEHIAEI
Sbjct  417  PNNLFYNTGITTYIWLLNNNKPENRQGKVQLIDASLLFRKLRKNLGNKNCEFSPEHIAEI  476

Query  481  TQNYLDFTAKARETDSQNEAVGLASQIFDNQDFGYYKVTIERPDRRSAQFTAENISPLRF  540
               YL+  +  R  D + ++VG+A+Q+F NQDFGYYKV IERPDRR+AQF A+ I PLRF
Sbjct  477  VSTYLENQSVERAIDEKGDPVGIAAQVFKNQDFGYYKVNIERPDRRNAQFRADLIEPLRF  536

Query  541  DKALFEPMQYLYRQYGEQIYNAGFLAQTEQEITAWCEAQGIALNNKNKTKLLDVKTWEKA  600
            +++  E M+YLY +YGEQ+Y+AGF+   E+EIT WCE ++I+LN+  KTKLLD K W K 
Sbjct  537  ENSQREVMEYLYAEYGEQVYDAGFVKGIEKEITKWCEENDISLNKAAKTKLLDTKNWMKQ  596

Query  601  AALFQTASTLLEHFGEQQFDDFNQFKQAVECRLKAEKIPLSATEKKAVFNAVSWYDENSA  660
             +L ++AS L   +G++ ++DFNQFKQ V+  L +  + LSA EKKA+++AVSWYDEN+ 
Sbjct  597  RTLVNAASQLHKKIGDEVYNDFNQFKQLVDAELTSLGLKLSAPEKKAILDAVSWYDENAE  656

Query  661  KVIAKTLKLKPNELDALCQRYQCQADELADFGYYATGKAGEYILYETSSDLRDSESIPLK  720
            KVI K  KLK + LD L + Y+C+ ++L+DFGYY+TG+  E++ YE+SSDLRDSES+PL 
Sbjct  657  KVIKKVAKLKQDKLDDLLENYECELEDLPDFGYYPTGNHNEFVTYESSSDLRDSESVPLE  716

Query  721  QNIHDYFKAEVQAHISEAWLNMESVKIGYEISFNKYFYRHKPLRSLAEVAQDILALEKQA  780
            Q+I +YF  EV++H+ EAW+N+ESVKIGYEISFNKYFYRHKPLRS+ EVA++I+ALE++A
Sbjct  717  QSIYQYFLDEVKPHVDEAWVNLESVKIGYEISFNKYFYRHKPLRSMDEVAKEIIALEQKA  776

Query  781  DGLISEIL  788
            +GLI++IL
Sbjct  777  EGLIADIL  784

26) hsdM2 in NC_017451


> EU272902|18|G17|167832524|ACA01834.1|Vibrio_cholerae_Amazonia_3509|-|21794..24175|-|VPI2_0017c|DNA 
methylase HsdM
Length=793

 Score =  975 bits (3696),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 555/788 (71%), Positives = 680/788 (87%), Gaps = 4/788 (0%)

Query  1    MEHSVHNKLVSFIWSIADDCLRDVYVRGKYRDVILPMFVLRRLDTLLEPSKDAVLEEMRF  60
            M+HSVHNKLVSFIWSIADDCLRDVYVRGKYRDVILPM VLRRLDTLLEPSK+AVLEE+RF
Sbjct  1    MDHSVHNKLVSFIWSIADDCLRDVYVRGKYRDVILPMVVLRRLDTLLEPSKEAVLEEVRF  60

Query  61   QKEELAFTELDDLPLKKITGHVFYNTSKWTLKSLYQTASNTPQYMLANFEEYLDGFSTNV  120
            QKEE+   ELDD PL   +G VFYNTSKWTL++L+ TA+N  Q +LANFE+YL+GFS NV
Sbjct  61   QKEEMNEIELDDAPLCATSGYVFYNTSKWTLQTLFSTATNNQQILLANFEDYLNGFSENV  120

Query  121  HEIINCFKLREQIRHMSHKNVLLSVLEKFVSPYINLTPKEQQDPEGNKLPALTNLGMGYV  180
             EI++CF+L+ QIRHM+ KNVLL V+EKFVSPYINLTP  ++DPEGNKLPAL+NLGMGYV
Sbjct  121  KEIVECFNLKAQIRHMAGKNVLLDVVEKFVSPYINLTPAVKEDPEGNKLPALSNLGMGYV  180

Query  181  FEELIRKFNEENNEEAGEHFTPREVIELMTHLVFDPLKDQIPAIITIYDPACGSGGMLTE  240
            FEELIRKFNEENNEEAGEHFTPREVIELMTHLVFDP+KD++P  IT+YDPACGSGGMLTE
Sbjct  181  FEELIRKFNEENNEEAGEHFTPREVIELMTHLVFDPIKDNLPLSITVYDPACGSGGMLTE  240

Query  241  SQNFIEQKYPLSESQGERSIFLFGKETNDETYAICKSDMMIKGDNPENIKVGSTLATDSF  300
            +QNF+E+KYP     ++R I+L+GKE NDETYAICKSDMMIKG+NPENI+VGSTL+TD F
Sbjct  241  TQNFVEEKYP----ASNRDIYLYGKEINDETYAICKSDMMIKGNNPENIRVGSTLSTDEF  296

Query  301  QGNHFDFMLSNPPYGKSWSKDQAYIKDGNEVIDSRFKVTLPDYWGNVETLDATPRSSDGQ  360
             +N+FDFMLSNPPYGKSW+ +Q  IK+G+EV+D+RFKV L DYWG     +A PRSSDGQ
Sbjct  297  SSNRFDFMLSNPPYGKSWASEQKHIKEGKEVVDGRFKVKLKDYWGVESEQEAIPRSSDGQ  356

Query  361  LLFLMEMVNKMKSPKNNKIGSRVASVHNGSSLFTGDAGSGESNIRRHIIENDLLEAIVKL  420
            LLFLMEMV KMKSP+++ +GSR+ASVHNGSSLFTGDAGSGESNIRR IIEND+L+AIV+L
Sbjct  357  LLFLMEMVTKMKSPQDSPLGSRIASVHNGSSLFTGDAGSGESNIRRYIIENDMLDAIVQL  416

Query  421  PNNLFYNTGITTYIWLLSNNKSEARKGKVQLIDASLLFRKLRKNLGDKNCEFAPEHIAEI  480
            PNNLFYNTGITTYIWLL+NNK+E R+GKVQLIDASLLFRKLRKNLG+KNCEF+PEHIAEI
Sbjct  417  PNNLFYNTGITTYIWLLNNNKPENRQGKVQLIDASLLFRKLRKNLGNKNCEFSPEHIAEI  476

Query  481  TQNYLDFTAKAREIDSQNEAVGLASQMFDNQDFGYYKVTIERPDRRSAQFTAENIEPLRF  540
               YL+  +  R ID + ++VG+A+Q+F NQDFGYYKV IERPDRR+AQF A+ IEPLRF
Sbjct  477  VSTYLENQSVERAIDEKGDPVGIAAQVFKNQDFGYYKVNIERPDRRNAQFRADLIEPLRF  536

Query  541  DKALFEPMQYLYRQYGGQVYNAGFLAQTEQEITAWCEAQGIALNNKNKAKLLDVKTWEKA  600
            +++  E M+YLY +YG QVY+AGF+   E+EIT WCE ++I+LN+  K+KLLD K W K 
Sbjct  537  ENSQREVMEYLYAEYGEQVYDAGFVKGIEKEITKWCEENDISLNKAAKTKLLDTKNWMKQ  596

Query  601  AALFQTASKLLKHFGEQQFHDFNQFKQAVECRLKAEKIPLSATEKKAVFNAVSWYNENAA  660
             +L ++AS+L K +G++ ++DFNQFKQ V+  L +  + LSA EKKA+++AVSWY+ENA 
Sbjct  597  RTLVNAASQLHKKIGDEVYNDFNQFKQLVDAELTSLGLKLSAPEKKAILDAVSWYDENAE  656

Query  661  KVIAKTLKLKPNELDALCQRYQCQADELADFGYYATGKAGEYILYETSSDLRDSESIPLK  720
            KVI K  KLK + LD L + Y+C+ ++L+DFGYY+TG+  E++ YE+SSDLRDSES+PL 
Sbjct  657  KVIKKVAKLKQDKLDDLLENYECELEDLPDFGYYPTGNHNEFVTYESSSDLRDSESVPLE  716

Query  721  QNIHDYFKAEVQAHISEAWLNMESVKIGYEISFNKYFYRHKPLRSLAEVAQDILALEKQA  780
            Q+I +YF  EV++H+ EAW+N+ESVKIGYEISFNKYFYRHKPLRS+ EVA++I+ALE++A
Sbjct  717  QSIYQYFLDEVKPHVDEAWVNLESVKIGYEISFNKYFYRHKPLRSMDEVAKEIIALEQKA  776

Query  781  DGLISEIL  788
            +GLI++IL
Sbjct  777  EGLIADIL  784

27) CGSHiEE_02765 in NC_009566


> EU272902|18|G17|167832524|ACA01834.1|Vibrio_cholerae_Amazonia_3509|-|21794..24175|-|VPI2_0017c|DNA 
methylase HsdM
Length=793

 Score =  971 bits (3678),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 551/788 (70%), Positives = 672/788 (86%), Gaps = 4/788 (0%)

Query  1    MEHSVHNKLVSFIWSIADDCLRDVYVRGKYRDVILPMFVLRRLDTLLEPSKDAVLEEMRF  60
            M+HSVHNKLVSFIWSIADDCLRDVYVRGKYRDVILPM VLRRLDTLLEPSK+AVLEE+RF
Sbjct  1    MDHSVHNKLVSFIWSIADDCLRDVYVRGKYRDVILPMVVLRRLDTLLEPSKEAVLEEVRF  60

Query  61   QKEELAFTELDDLPLKKITGYVFYNTSKWTLKSLYQTAGNTPQHMLANFEEYLDGFSTNV  120
            QKEE+   ELDD PL   +GYVFYNTSKWTL++L+ TA N  Q +LANFE+YL+GFS NV
Sbjct  61   QKEEMNEIELDDAPLCATSGYVFYNTSKWTLQTLFSTATNNQQILLANFEDYLNGFSENV  120

Query  121  QEIIKCFKLSEQIRHMSHKNVLLSVLEKFVSPYINLTPKEQQDPEDNKLPALTNLGMGYV  180
            +EI+ CF+L  QIRHM+ KNVLL V+EKFVSPYINLTP  ++DPE+NKLPAL+NLGMGYV
Sbjct  121  KEIVECFNLKAQIRHMAGKNVLLDVVEKFVSPYINLTPAVKEDPEGNKLPALSNLGMGYV  180

Query  181  FEELIRKFNEENNEEAGEHFTPREVIELMTHLVFDPLKDQIPAIITIYDPACGSGGMLTE  240
            FEELIRKFNEENNEEAGEHFTPREVIELMTHLVFDP+KD++P  IT+YDPACGSGGMLTE
Sbjct  181  FEELIRKFNEENNEEAGEHFTPREVIELMTHLVFDPIKDNLPLSITVYDPACGSGGMLTE  240

Query  241  SQNFIEQKYPLSESQGERSIFLFGKETNDETYAICKSDMMIKGDNPENIKVGSTLATDSF  300
            +QNF+E+KYP     ++R I+L+GKE NDETYAICKSDMMIKG+NPENI+VGSTL+TD F
Sbjct  241  TQNFVEEKYP----ASNRDIYLYGKEINDETYAICKSDMMIKGNNPENIRVGSTLSTDEF  296

Query  301  QGNHFDFMLSNPPYGKSWSKDQAYIKDGNEVIDSRFKVTLPDYWGNVETLDATPRSSDGQ  360
             +N+FDFMLSNPPYGKSW+ +Q  IK+G+EV+D+RFKV L DYWG     +A PRSSDGQ
Sbjct  297  SSNRFDFMLSNPPYGKSWASEQKHIKEGKEVVDGRFKVKLKDYWGVESEQEAIPRSSDGQ  356

Query  361  LLFLMEMVNKMKSPKNNKIGSRVASVHNGSSLFTGDAGSGESNIRRHIIEKDLLEAIVQL  420
            LLFLMEMV KMKSP+++ +GSR+ASVHNGSSLFTGDAGSGESNIRR IIE+D+L+AIVQL
Sbjct  357  LLFLMEMVTKMKSPQDSPLGSRIASVHNGSSLFTGDAGSGESNIRRYIIENDMLDAIVQL  416

Query  421  PNNLFYNTGITTYIWLLSNNKPEARKGKVQLIDAGLLFRKLRKNLGDKNCEFAPEHIAEI  480
            PNNLFYNTGITTYIWLL+NNKPE R+GKVQLIDA+LLFRKLRKNLG+KNCEF+PEHIAEI
Sbjct  417  PNNLFYNTGITTYIWLLNNNKPENRQGKVQLIDASLLFRKLRKNLGNKNCEFSPEHIAEI  476

Query  481  TQNYLDFTAKARETDSQNEAVGLASQIFDNQDFGYYKVTIERPDRRSAQFTAENIAPLRF  540
               YL+  +  R  D + ++VG+A+Q+F NQDFGYYKV IERPDRR+AQF A+ I PLRF
Sbjct  477  VSTYLENQSVERAIDEKGDPVGIAAQVFKNQDFGYYKVNIERPDRRNAQFRADLIEPLRF  536

Query  541  DKALFEPMQYLYQQHGEQVYNAEYLAKTEPEISTWCEAQGIALNNKNKAKLLDVKTWEKA  600
            +++  E M+YLY + GEQVY+A ++   E EI+ WCE ++I+LN+  K+KLLD K W K 
Sbjct  537  ENSQREVMEYLYAEYGEQVYDAGFVKGIEKEITKWCEENDISLNKAAKTKLLDTKNWMKQ  596

Query  601  ATLFQTASTLLEHFGSTQFDDFNQFKQAVEGRLKTEKIPLSATEKKAIFNAVSWYNENAA  660
             TL ++AS L   +G   ++DFNQFKQ V++ L +  + LSA EKKAI++AVSWY+ENA 
Sbjct  597  RTLVNAASQLHKKIGDEVYNDFNQFKQLVDAELTSLGLKLSAPEKKAILDAVSWYDENAE  656

Query  661  KVIAKTLKLKPNELDALCQRYQCQADELADFGYYATGKAGEYIQYETSSDLRDSESIPLK  720
            KVI K  KLK + LD L + Y+C+ ++L+DFGYY+TG+  E++ YE+SSDLRDSES+PL 
Sbjct  657  KVIKKVAKLKQDKLDDLLENYECELEDLPDFGYYPTGNHNEFVTYESSSDLRDSESVPLE  716

Query  721  QNILDYFKAEVQPHISEAWLNMENVKIGYEISFNKYFYRHKPLRSLAEVAQDILALEKQA  780
            Q+I +YF  EV+PH+ EAW+N+E+VKIGYEISFNKYFYRHKPLRS+ EVA++I+ALE++A
Sbjct  717  QSIYQYFLDEVKPHVDEAWVNLESVKIGYEISFNKYFYRHKPLRSMDEVAKEIIALEQKA  776

Query  781  DGLISEIL  788
            +GLI++IL
Sbjct  777  EGLIADIL  784

28) hsdM2 in NC_017452


> EU272902|18|G17|167832524|ACA01834.1|Vibrio_cholerae_Amazonia_3509|-|21794..24175|-|VPI2_0017c|DNA 
methylase HsdM
Length=793

 Score =  971 bits (3678),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 551/788 (70%), Positives = 672/788 (86%), Gaps = 4/788 (0%)

Query  1    MEHSVHNKLVSFIWSIADDCLRDVYVRGKYRDVILPMFVLRRLDTLLEPSKDAVLEEMRF  60
            M+HSVHNKLVSFIWSIADDCLRDVYVRGKYRDVILPM VLRRLDTLLEPSK+AVLEE+RF
Sbjct  1    MDHSVHNKLVSFIWSIADDCLRDVYVRGKYRDVILPMVVLRRLDTLLEPSKEAVLEEVRF  60

Query  61   QKEELAFTELDDLPLKKITGYVFYNTSKWTLKSLYQTAGNTPQHMLANFEEYLDGFSTNV  120
            QKEE+   ELDD PL   +GYVFYNTSKWTL++L+ TA N  Q +LANFE+YL+GFS NV
Sbjct  61   QKEEMNEIELDDAPLCATSGYVFYNTSKWTLQTLFSTATNNQQILLANFEDYLNGFSENV  120

Query  121  QEIIKCFKLSEQIRHMSHKNVLLSVLEKFVSPYINLTPKEQQDPEDNKLPALTNLGMGYV  180
            +EI+ CF+L  QIRHM+ KNVLL V+EKFVSPYINLTP  ++DPE+NKLPAL+NLGMGYV
Sbjct  121  KEIVECFNLKAQIRHMAGKNVLLDVVEKFVSPYINLTPAVKEDPEGNKLPALSNLGMGYV  180

Query  181  FEELIRKFNEENNEEAGEHFTPREVIELMTHLVFDPLKDQIPAIITIYDPACGSGGMLTE  240
            FEELIRKFNEENNEEAGEHFTPREVIELMTHLVFDP+KD++P  IT+YDPACGSGGMLTE
Sbjct  181  FEELIRKFNEENNEEAGEHFTPREVIELMTHLVFDPIKDNLPLSITVYDPACGSGGMLTE  240

Query  241  SQNFIEQKYPLSESQGERSIFLFGKETNDETYAICKSDMMIKGDNPENIKVGSTLATDSF  300
            +QNF+E+KYP     ++R I+L+GKE NDETYAICKSDMMIKG+NPENI+VGSTL+TD F
Sbjct  241  TQNFVEEKYP----ASNRDIYLYGKEINDETYAICKSDMMIKGNNPENIRVGSTLSTDEF  296

Query  301  QGNHFDFMLSNPPYGKSWSKDQAYIKDGNEVIDSRFKVTLPDYWGNVETLDATPRSSDGQ  360
             +N+FDFMLSNPPYGKSW+ +Q  IK+G+EV+D+RFKV L DYWG     +A PRSSDGQ
Sbjct  297  SSNRFDFMLSNPPYGKSWASEQKHIKEGKEVVDGRFKVKLKDYWGVESEQEAIPRSSDGQ  356

Query  361  LLFLMEMVNKMKSPKNNKIGSRVASVHNGSSLFTGDAGSGESNIRRHIIEKDLLEAIVQL  420
            LLFLMEMV KMKSP+++ +GSR+ASVHNGSSLFTGDAGSGESNIRR IIE+D+L+AIVQL
Sbjct  357  LLFLMEMVTKMKSPQDSPLGSRIASVHNGSSLFTGDAGSGESNIRRYIIENDMLDAIVQL  416

Query  421  PNNLFYNTGITTYIWLLSNNKPEARKGKVQLIDAGLLFRKLRKNLGDKNCEFAPEHIAEI  480
            PNNLFYNTGITTYIWLL+NNKPE R+GKVQLIDA+LLFRKLRKNLG+KNCEF+PEHIAEI
Sbjct  417  PNNLFYNTGITTYIWLLNNNKPENRQGKVQLIDASLLFRKLRKNLGNKNCEFSPEHIAEI  476

Query  481  TQNYLDFTAKARETDSQNEAVGLASQIFDNQDFGYYKVTIERPDRRSAQFTAENIAPLRF  540
               YL+  +  R  D + ++VG+A+Q+F NQDFGYYKV IERPDRR+AQF A+ I PLRF
Sbjct  477  VSTYLENQSVERAIDEKGDPVGIAAQVFKNQDFGYYKVNIERPDRRNAQFRADLIEPLRF  536

Query  541  DKALFEPMQYLYQQHGEQVYNAEYLAKTEPEISTWCEAQGIALNNKNKAKLLDVKTWEKA  600
            +++  E M+YLY + GEQVY+A ++   E EI+ WCE ++I+LN+  K+KLLD K W K 
Sbjct  537  ENSQREVMEYLYAEYGEQVYDAGFVKGIEKEITKWCEENDISLNKAAKTKLLDTKNWMKQ  596

Query  601  ATLFQTASTLLEHFGSTQFDDFNQFKQAVEGRLKTEKIPLSATEKKAIFNAVSWYNENAA  660
             TL ++AS L   +G   ++DFNQFKQ V++ L +  + LSA EKKAI++AVSWY+ENA 
Sbjct  597  RTLVNAASQLHKKIGDEVYNDFNQFKQLVDAELTSLGLKLSAPEKKAILDAVSWYDENAE  656

Query  661  KVIAKTLKLKPNELDALCQRYQCQADELADFGYYATGKAGEYIQYETSSDLRDSESIPLK  720
            KVI K  KLK + LD L + Y+C+ ++L+DFGYY+TG+  E++ YE+SSDLRDSES+PL 
Sbjct  657  KVIKKVAKLKQDKLDDLLENYECELEDLPDFGYYPTGNHNEFVTYESSSDLRDSESVPLE  716

Query  721  QNILDYFKAEVQPHISEAWLNMENVKIGYEISFNKYFYRHKPLRSLAEVAQDILALEKQA  780
            Q+I +YF  EV+PH+ EAW+N+E+VKIGYEISFNKYFYRHKPLRS+ EVA++I+ALE++A
Sbjct  717  QSIYQYFLDEVKPHVDEAWVNLESVKIGYEISFNKYFYRHKPLRSMDEVAKEIIALEQKA  776

Query  781  DGLISEIL  788
            +GLI++IL
Sbjct  777  EGLIADIL  784

29) HICON_03790 in NC_014922


> EU272902|18|G17|167832524|ACA01834.1|Vibrio_cholerae_Amazonia_3509|-|21794..24175|-|VPI2_0017c|DNA 
methylase HsdM
Length=793

 Score =  969 bits (3672),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 552/788 (71%), Positives = 673/788 (86%), Gaps = 4/788 (0%)

Query  1    MDHSVHNKLVSFIWSIADDCLRDVYVRGKYRDVILPMFVLRRLDTLLEPSKDAVLEEMRF  60
            MDHSVHNKLVSFIWSIADDCLRDVYVRGKYRDVILPM VLRRLDTLLEPSK+AVLEE+RF
Sbjct  1    MDHSVHNKLVSFIWSIADDCLRDVYVRGKYRDVILPMVVLRRLDTLLEPSKEAVLEEVRF  60

Query  61   QKEELAFTELDDLPLKKITGHVFYNTSKWTLKSLYQTASNTPQYMLANFEEYLDGFSTNV  120
            QKEE+   ELDD PL   +G VFYNTSKWTL++L+ TA+N  Q +LANFE+YL+GFS NV
Sbjct  61   QKEEMNEIELDDAPLCATSGYVFYNTSKWTLQTLFSTATNNQQILLANFEDYLNGFSENV  120

Query  121  HEIINCFKLREQIRHMSHKNVLLSVLEKFVSPYINLTPKEQQDTEGNKLPALTNLGMGYV  180
             EI++CF+L+ QIRHM+ KNVLL V+EKFVSPYINLTP  ++D EGNKLPAL+NLGMGYV
Sbjct  121  KEIVECFNLKAQIRHMAGKNVLLDVVEKFVSPYINLTPAVKEDPEGNKLPALSNLGMGYV  180

Query  181  FEELIRKFNEENNEEAGEHFTPREVIELMTHLVFDPLKDQIPAIITIYDPACGSGGMLTE  240
            FEELIRKFNEENNEEAGEHFTPREVIELMTHLVFDP+KD++P  IT+YDPACGSGGMLTE
Sbjct  181  FEELIRKFNEENNEEAGEHFTPREVIELMTHLVFDPIKDNLPLSITVYDPACGSGGMLTE  240

Query  241  SQNFIEQKYPLSESQGERSIFLFGKETNDETYAICKSDMMIKGDNPENIKVGSTLATDSF  300
            +QNF+E+KYP     ++R I+L+GKE NDETYAICKSDMMIKG+NPENI+VGSTL+TD F
Sbjct  241  TQNFVEEKYP----ASNRDIYLYGKEINDETYAICKSDMMIKGNNPENIRVGSTLSTDEF  296

Query  301  QGNHFDFMLSNPPYGKSWSKDQAYIKDGNEVIDSRFKVTLPDYWGNVETLDATPRSSDGQ  360
             +N+FDFMLSNPPYGKSW+ +Q  IK+G+EV+D+RFKV L DYWG     +A PRSSDGQ
Sbjct  297  SSNRFDFMLSNPPYGKSWASEQKHIKEGKEVVDGRFKVKLKDYWGVESEQEAIPRSSDGQ  356

Query  361  LLFLMEMVNKMKSPKNNKIGSRVASVHNGSSLFTGDAGSGESNIRRHIIENDLLEAIVQL  420
            LLFLMEMV KMKSP+++ +GSR+ASVHNGSSLFTGDAGSGESNIRR IIEND+L+AIVQL
Sbjct  357  LLFLMEMVTKMKSPQDSPLGSRIASVHNGSSLFTGDAGSGESNIRRYIIENDMLDAIVQL  416

Query  421  PNNLFYNTGITTYIWLLSNNKPEARKGKVQLIDASLLFRKLRKNLGDKNCEFVPEHISEI  480
            PNNLFYNTGITTYIWLL+NNKPE R+GKVQLIDASLLFRKLRKNLG+KNCEF PEHI+EI
Sbjct  417  PNNLFYNTGITTYIWLLNNNKPENRQGKVQLIDASLLFRKLRKNLGNKNCEFSPEHIAEI  476

Query  481  TQNYLDFTAKARETDSQNEAVGLASQIFDNQDFGYYKVTIERPDRRSAQFTVENIASLRF  540
               YL+  +  R  D + ++VG+A+Q+F NQDFGYYKV IERPDRR+AQF  + I +LRF
Sbjct  477  VSTYLENQSVERAIDEKGDPVGIAAQVFKNQDFGYYKVNIERPDRRNAQFRADLIEPLRF  536

Query  541  DKALFEPMQYLYRQYGGQVYNAGFLTQTEQEITAWCEAQGIALNNKNKAKLLDVKTWEKA  600
            +++  E M+YLY +YG QVY+AGF+   E+EIT WCE ++I+LN+  K+KLLD K W K 
Sbjct  537  ENSQREVMEYLYAEYGEQVYDAGFVKGIEKEITKWCEENDISLNKAAKTKLLDTKNWMKQ  596

Query  601  AALFQTASKLLEHFGEQQFDDFNQFKQAVECRLKTEKIPLSATEKKAIFNAVSWYDENSA  660
             +L ++AS+L   +G++ ++DFNQFKQ V+  L +  + LSA EKKAI++AVSWYDEN+ 
Sbjct  597  RTLVNAASQLHKKIGDEVYNDFNQFKQLVDAELTSLGLKLSAPEKKAILDAVSWYDENAE  656

Query  661  KVIAKTLKLKPNELDALCQRYQCQADGLADFGYYTTGKAGEYILYETSSDLRDSESIPLK  720
            KVI K  KLK + LD L + Y+C+ ++L+DFGYY TG+  E++ YE+SSDLRDSES+PL 
Sbjct  657  KVIKKVAKLKQDKLDDLLENYECELEDLPDFGYYPTGNHNEFVTYESSSDLRDSESVPLE  716

Query  721  QNIHDYFKAEVQAHISEAWLNMESVKIGYEISFNKYFYRHKPLRSLAEVAQDILALEKQA  780
            Q+I +YF  EV++H+ EAW+N+ESVKIGYEISFNKYFYRHKPLRS+ EVA++I+ALE++A
Sbjct  717  QSIYQYFLDEVKPHVDEAWVNLESVKIGYEISFNKYFYRHKPLRSMDEVAKEIIALEQKA  776

Query  781  DGLISEIL  788
            +GLI++IL
Sbjct  777  EGLIADIL  784

30) hsdM1 in NC_014920


> EU272902|18|G17|167832524|ACA01834.1|Vibrio_cholerae_Amazonia_3509|-|21794..24175|-|VPI2_0017c|DNA 
methylase HsdM
Length=793

 Score =  969 bits (3670),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 549/788 (70%), Positives = 675/788 (86%), Gaps = 4/788 (0%)

Query  1    MDHSVHNKLVSFIWSIADDCLRDVYVRGKYRDVILPMFVLRRLDTLLEPSKDAVLEEMRF  60
            MDHSVHNKLVSFIWSIADDCLRDVYVRGKYRDVILPM VLRRLDTLLEPSK+AVLEE+RF
Sbjct  1    MDHSVHNKLVSFIWSIADDCLRDVYVRGKYRDVILPMVVLRRLDTLLEPSKEAVLEEVRF  60

Query  61   QKEELAFTELDDLPLKKITGHVFYNTSKWTLKSLYQTASNTPQYMLANFEEYLDGFSTNV  120
            QKEE+   ELDD PL   +G VFYNTSKWTL++L+ TA+N  Q +LANFE+YL+GFS NV
Sbjct  61   QKEEMNEIELDDAPLCATSGYVFYNTSKWTLQTLFSTATNNQQILLANFEDYLNGFSENV  120

Query  121  HEIINCFKLREQIRHMSHKNVLLSVLEKFVSPYINLTPKEQQDPEGNKLPALTNLGMGYV  180
             EI++CF+L+ QIRHM+ KNVLL V+EKFVSPYINLTP  ++DPEGNKLPAL+NLGMGYV
Sbjct  121  KEIVECFNLKAQIRHMAGKNVLLDVVEKFVSPYINLTPAVKEDPEGNKLPALSNLGMGYV  180

Query  181  FEELIRKFNEENNEEAGEHFTPREVIELMTHLVFDPLKDQIPAIITIYDPACGSGGMLTE  240
            FEELIRKFNEENNEEAGEHFTPREVIELMTHLVFDP+KD++P  IT+YDPACGSGGMLTE
Sbjct  181  FEELIRKFNEENNEEAGEHFTPREVIELMTHLVFDPIKDNLPLSITVYDPACGSGGMLTE  240

Query  241  SQNFIEQKYPLSESQGERSIFLFGKETNDETYAICKSDMMIKGDNPENIKVGSTLATDSF  300
            +QNF+E+KYP     ++R I+L+GKE NDETYAICKSDMMIKG+NPENI+VGSTL+TD F
Sbjct  241  TQNFVEEKYP----ASNRDIYLYGKEINDETYAICKSDMMIKGNNPENIRVGSTLSTDEF  296

Query  301  QGNHFDFMLSNPPYGKSWSKDQAYIKDGNEVIDSRFKVTLPDYWGNVETLDATPRSSDGQ  360
             +N+FDFMLSNPPYGKSW+ +Q  IK+G+EV+D+RFKV L DYWG     +A PRSSDGQ
Sbjct  297  SSNRFDFMLSNPPYGKSWASEQKHIKEGKEVVDGRFKVKLKDYWGVESEQEAIPRSSDGQ  356

Query  361  LLFLMEMVNKMKSPKNNKIGSRVASVHNGSSLFTGDAGSGESNIRRHIIEKDLLEAIVQL  420
            LLFLMEMV KMKSP+++ +GSR+ASVHNGSSLFTGDAGSGESNIRR IIE+D+L+AIVQL
Sbjct  357  LLFLMEMVTKMKSPQDSPLGSRIASVHNGSSLFTGDAGSGESNIRRYIIENDMLDAIVQL  416

Query  421  PNNLFYNTGITTYIWLLSNNKSEARKGKVQLIDASLLFRKLRKNLGDKNCEFVPEHISEI  480
            PNNLFYNTGITTYIWLL+NNK+E R+GKVQLIDASLLFRKLRKNLG+KNCEF PEHI+EI
Sbjct  417  PNNLFYNTGITTYIWLLNNNKPENRQGKVQLIDASLLFRKLRKNLGNKNCEFSPEHIAEI  476

Query  481  TQNYLDFTAKARETDSQNEAVGLASQIFDNQDFGYYKVTIERPDRRSAQFTVENIASLRF  540
               YL+  +  R  D + ++VG+A+Q+F NQDFGYYKV IERPDRR+AQF  + I +LRF
Sbjct  477  VSTYLENQSVERAIDEKGDPVGIAAQVFKNQDFGYYKVNIERPDRRNAQFRADLIEPLRF  536

Query  541  DKALFEPMQYLYRQYGGQVYNARFLAKTEQEITAWCEAQGIALNNKNKAKLLDVKTWEKA  600
            +++  E M+YLY +YG QVY+A F+   E+EIT WCE ++I+LN+  K+KLLD K W K 
Sbjct  537  ENSQREVMEYLYAEYGEQVYDAGFVKGIEKEITKWCEENDISLNKAAKTKLLDTKNWMKQ  596

Query  601  AALFQTASKLLEHFGEQQFHDFNQFKQAVEGRLKTEKIPLSATEKKAVFNAVSWYDENSA  660
             +L ++AS+L   +G++ ++DFNQFKQ V++ L +  + LSA EKKA+++AVSWYDEN+ 
Sbjct  597  RTLVNAASQLHKKIGDEVYNDFNQFKQLVDAELTSLGLKLSAPEKKAILDAVSWYDENAE  656

Query  661  KVIAKTLKLKPNELDALCQRYQCQADELADFGYYATGKAGEYILYETSSDLRDSESIPLK  720
            KVI K  KLK + LD L + Y+C+ ++L+DFGYY+TG+  E++ YE+SSDLRDSES+PL 
Sbjct  657  KVIKKVAKLKQDKLDDLLENYECELEDLPDFGYYPTGNHNEFVTYESSSDLRDSESVPLE  716

Query  721  QNIHDYFKAEVQAHISEAWLNMESVKIGYEISFNKYFYRHKPLRSLAEVAQDILALEKQA  780
            Q+I +YF  EV++H+ EAW+N+ESVKIGYEISFNKYFYRHKPLRS+ EVA++I+ALE++A
Sbjct  717  QSIYQYFLDEVKPHVDEAWVNLESVKIGYEISFNKYFYRHKPLRSMDEVAKEIIALEQKA  776

Query  781  DGLISEIL  788
            +GLI++IL
Sbjct  777  EGLIADIL  784

31) PBPRA0882 in NC_006370


> EU272902|18|G17|167832524|ACA01834.1|Vibrio_cholerae_Amazonia_3509|-|21794..24175|-|VPI2_0017c|DNA 
methylase HsdM
Length=793

 Score =  965 bits (3655),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 569/788 (73%), Positives = 680/788 (87%), Gaps = 9/788 (1%)

Query  2    FSWSIADDCLRDVYVRGKYRDVILPMVVLRRLDSLLEATKKEILEEVAFQRDEMESTEFD  61
            F WSIADDCLRDVYVRGKYRDVILPMVVLRRLD+LLE++K  +LEEV FQ++EM+  E+D
Sbjct  12   FIWSIADDCLRDVYVRGKYRDVILPMVVLRRLDTLLEPSKEAVLEEVRFQKEEMNEIELD  71

Query  62   SAPLEAITGYVFYNTSKWTLKQITATASNNQQILLANVEEYLNGFSDNVKEIIKCFKLQS  121
             APL A +GYVFYNTSKWTL+ + +TA+NNQQILLAN E+YLNGFS+NVKEI+ CF+L++
Sbjct  72   DAPLCATSGYVFYNTSKWTLQTLFSTATNNQQILLANFEDYLNGFSENVKEIVECFNLKA  131

Query  122  QIRHMAEKDILLDVLEKFTSPNINLTPNVVEDPDGNKLPALSNLGMGYVFEELIRKFNED  181
            QIRHMA K++LLDV+EKF SP INLTP V EDP+GNKLPALSNLGMGYVFEELIRKFNE+
Sbjct  132  QIRHMAGKNVLLDVVEKFVSPYINLTPAVKEDPEGNKLPALSNLGMGYVFEELIRKFNEE  191

Query  182  NNEEAGEHFTPREVIELMTHLVFDPLKGNLPPVITLYDPACGSGGMLTEAQNFIKDPEGK  241
            NNEEAGEHFTPREVIELMTHLVFDP+K+NLP  IT+YDPACGSGGMLTE+QNF+   E K
Sbjct  192  NNEEAGEHFTPREVIELMTHLVFDPIKDNLPLSITVYDPACGSGGMLTETQNFV---EEK  248

Query  242  IKATS-DVYLFGKEINDETYAICKSDMMIKGDNPENIRVGSTLSTDEFAGKTFHYCLSNP  300
              A++ D+YL+GKEINDETYAICKSDMMIKG+NPENIRVGSTLSTDEF+++ F++ LSNP
Sbjct  249  YPASNRDIYLYGKEINDETYAICKSDMMIKGNNPENIRVGSTLSTDEFSSNRFDFMLSNP  308

Query  301  PYGKSWASEQKYIKDGKEVIDSRFKVKLKDYWGVEDTYEAIPRSSDGQLLFLMEMVSKMK  360
            PYGKSWASEQK IK+GKEV+D+RFKVKLKDYWGVE   EAIPRSSDGQLLFLMEMV+KMK
Sbjct  309  PYGKSWASEQKHIKEGKEVVDGRFKVKLKDYWGVESEQEAIPRSSDGQLLFLMEMVTKMK  368

Query  361  SVNNGVEGSRIASVHNGSSLFTGDAGGGESNIRRYIIENDMLEAIVQLPNNLFYNTGITT  420
            S +++  GSRIASVHNGSSLFTGDAG+GESNIRRYIIENDML+AIVQLPNNLFYNTGITT
Sbjct  369  SPQDSPLGSRIASVHNGSSLFTGDAGSGESNIRRYIIENDMLDAIVQLPNNLFYNTGITT  428

Query  421  YIWLLSNNKLDKRKGQVQLIDANPLYRKLRKNLGDKNCEFSPEHIREITKTYLDMTKVER  480
            YIWLL+NNK ++R+G+VQLIDA+ L+RKLRKNLG+KNCEFSPEHI EI  TYL+   VER
Sbjct  429  YIWLLNNNKPENRQGKVQLIDASLLFRKLRKNLGNKNCEFSPEHIAEIVSTYLENQSVER  488

Query  481  TLDEKGDPQGISTKVFDNDDFGYYKVNIECPDRRNAQFSSERIETLRFDKALREPMEYIY  540
            ++DEKGDP GI+++VF N+DFGYYKVNIE PDRRNAQF ++ IE LRF+++ RE MEY+Y
Sbjct  489  AIDEKGDPVGIAAQVFKNQDFGYYKVNIERPDRRNAQFRADLIEPLRFENSQREVMEYLY  548

Query  541  NTYGEDAYKAEILAKESKAILAWCEEKEISLNTKNRNKLLDVATWTRLGDLIDIANTLMK  600
              YGE+ Y A ++    K I  WCEE++ISLN   + KLLD   W +   L++ A+ L K
Sbjct  549  AEYGEQVYDAGFVKGIEKEITKWCEENDISLNKAAKTKLLDTKNWMKQRTLVNAASQLHK  608

Query  601  AIGTDIYNDYNQFKATVDAELKSRKIKLSAPEKNAILNAVSWYHENAEKVIKKKLKLTGS  660
             IG ++YND+NQFK  VDAEL S  +KLSAPEK+AIL+AVSWY+ENAEKVIKK  KL   
Sbjct  609  KIGDEVYNDFNQFKQLVDAELTSLGLKLSAPEKKAILDAVSWYDENAEKVIKKVAKLKQD  668

Query  661  KLDELLTSCDCDEHELGDFGYYLIAKEDGGKAGEYITYESNSDLRDAESIPLKQSIYQYF  720
            KLD+LL + +C+ ++L DFGYY       G+  E++TYES+SDLRD+ES+PL QSIYQYF
Sbjct  669  KLDDLLENYECELEDLPDFGYY-----PTGNHNEFVTYESSSDLRDSESVPLEQSIYQYF  723

Query  721  LDEVKPHVSDSWINIDSTKIGYEISFNKHFYQHKPLRSIDDVAKDIIALEQKAEGLMAEI  780
            LDEVKPHV ++W+N++S KIGYEISFNK FY+HKPLRS+D+VAK+IIALEQKAEGL+A+I
Sbjct  724  LDEVKPHVDEAWVNLESVKIGYEISFNKYFYRHKPLRSMDEVAKEIIALEQKAEGLIADI  783

Query  781  LGISVSTL  788
            LGISV+ +
Sbjct  784  LGISVAKV  791

32) Nhal_0751 in NC_013960


> EU272902|18|G17|167832524|ACA01834.1|Vibrio_cholerae_Amazonia_3509|-|21794..24175|-|VPI2_0017c|DNA 
methylase HsdM
Length=793

 Score =  960 bits (3639),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 566/799 (71%), Positives = 680/799 (86%), Gaps = 10/799 (1%)

Query  1    MNHAFHNKLVSFIWSIADDCLRDVYVRGKYRDVILPMVVLRRLDALLEPTKAAVLEEVRF  60
            M+H+ HNKLVSFIWSIADDCLRDVYVRGKYRDVILPMVVLRRLD+LLEP+K AVLEEVRF
Sbjct  1    MDHSVHNKLVSFIWSIADDCLRDVYVRGKYRDVILPMVVLRRLDTLLEPSKEAVLEEVRF  60

Query  61   QRKEMKLTELEDSALQAASGYVFYNASKWTLKQLYQTATNNQQILLANVEEYLSGYSGNV  120
            Q+ EM+  EL+D++L A+SGYVFYN+SKWTL+ L+ TATNNQQILLAN E+YL+G+S NV
Sbjct  61   QKEEMNEIELDDAPLCATSGYVFYNTSKWTLQTLFSTATNNQQILLANFEDYLNGFSENV  120

Query  121  KEIIGKFNLKAQVRHMAAKDVLLDVLEKFTSPYINLTHEEAQDPEGNRLPALSNLGMGYV  180
            KEI+  FNLKAQ+RHMA+K+VLLDV+EKF SPYINLT    +DPEGN+LPALSNLGMGYV
Sbjct  121  KEIVECFNLKAQIRHMAGKNVLLDVVEKFVSPYINLTPAVKEDPEGNKLPALSNLGMGYV  180

Query  181  FEELIRRFNEENNEEAGEHFTPREVIELMTHLVFDPVKDKLPPVMTIYDPACGSGGMLTE  240
            FEELIR+FNEENNEEAGEHFTPREVIELMTHLVFDP+KD+LP  +T+YDPACGSGGMLTE
Sbjct  181  FEELIRKFNEENNEEAGEHFTPREVIELMTHLVFDPIKDNLPLSITVYDPACGSGGMLTE  240

Query  241  SQNFIKDEEGAIRASGDVYLYGKEINDETYAICKSDMMIKGNNPANIRVGSTLSTDEFAG  300
            +QNF+ +   A  ++ D+YLYGKEINDETYAICKSDMMIKGNNP NIRVGSTLSTDEF++
Sbjct  241  TQNFVEEKYPA--SNRDIYLYGKEINDETYAICKSDMMIKGNNPENIRVGSTLSTDEFSS  298

Query  301  NRFDFMLSNPPYGKSWAGEQKYIKDGGEVIDPRFKVQLKDYWGHVETVDAAPRSSDGQLL  360
            NRFDFMLSNPPYGKSWA+EQK IK+G EV+D RFKV+LKDYWG     +A PRSSDGQLL
Sbjct  299  NRFDFMLSNPPYGKSWASEQKHIKEGKEVVDGRFKVKLKDYWGVESEQEAIPRSSDGQLL  358

Query  361  FLMEMISKMKAPQAGGLGSRIASVHNGSSLFTGDAGSGESNIRRHIIENDLLEAIIQLPN  420
            FLMEM++KMK+PQ + LGSRIASVHNGSSLFTGDAGSGESNIRR IIEND+L+AI+QLPN
Sbjct  359  FLMEMVTKMKSPQDSPLGSRIASVHNGSSLFTGDAGSGESNIRRYIIENDMLDAIVQLPN  418

Query  421  NLFYNTGITTYIWLLSNHKPEHRRGKAQLIDASRLYRKLRKNLGNKNCEFAPEHIREITQ  480
            NLFYNTGITTYIWLL+N+KPE+R+GK QLIDAS L+RKLRKNLGNKNCEF+PEHI EI  
Sbjct  419  NLFYNTGITTYIWLLNNNKPENRQGKVQLIDASLLFRKLRKNLGNKNCEFSPEHIAEIVS  478

Query  481  TYLELASIDRP----AGAEGIAAQVFDNRDFGYYKVAIERPDRRKAQFSTERIETLRFDK  536
            TYLE  S++R+    +++ GIAAQVF N+DFGYYKV IERPDRR+AQF ++ IE LRF++
Sbjct  479  TYLENQSVERAIDEKGDPVGIAAQVFKNQDFGYYKVNIERPDRRNAQFRADLIEPLRFEN  538

Query  537  ALGEPMAWIYGQWGDRVYEKGTLAEHEKAILAWCEEQALNLNAKQRKKLLNLETWRKHHT  596
            +  E M  +Y++ G++VY+ G +   EK I  WCEE+ ++LN   + KLL+   W K++T
Sbjct  539  SQREVMEYLYAEYGEQVYDAGFVKGIEKEITKWCEENDISLNKAAKTKLLDTKNWMKQRT  598

Query  597  LVQMAEHLMAVIGTDEFNDFNRFKTRVDKALKALAKETGVKLGVSDKNQLLNAVSKYDEN  656
            LV+ A +L   IG + +NDFN+FK  VD  L +L    G+KL+ ++K+ +L+AVS YDEN
Sbjct  599  LVNAASQLHKKIGDEVYNDFNQFKQLVDAELTSL----GLKLSAPEKKAILDAVSWYDEN  654

Query  657  AEKVIKKVEKFSQDQLRTLLQRLGCEESELADFGYYATEKPDEYLTYESSSDLRDSETIP  716
            AEKVIKKV K+ QD+L  LL+   CE  +L+DFGYY+T + +E++TYESSSDLRDSE++P
Sbjct  655  AEKVIKKVAKLKQDKLDDLLENYECELEDLPDFGYYPTGNHNEFVTYESSSDLRDSESVP  714

Query  717  LKDDIHQYFKAEVKPHVSEAWINMDSVKIGYEISFNKYFYRHQPLRSMEEVAREIIALEQ  776
            L + I QYF  EVKPHV EAW+N++SVKIGYEISFNKYFYRH+PLRSM+EVA+EIIALEQ
Sbjct  715  LEQSIYQYFLDEVKPHVDEAWVNLESVKIGYEISFNKYFYRHKPLRSMDEVAKEIIALEQ  774

Query  777  QAEGLIADILGIDVEEVSG  795
            +AEGLIADILGI V  V G
Sbjct  775  KAEGLIADILGISVAKVQG  793

33) hsdM in NC_017105


> EU272902|18|G17|167832524|ACA01834.1|Vibrio_cholerae_Amazonia_3509|-|21794..24175|-|VPI2_0017c|DNA 
methylase HsdM
Length=793

 Score =  943 bits (3574),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 551/792 (70%), Positives = 670/792 (85%), Gaps = 3/792 (0%)

Query  1    MNQTSHSSLVSFIWRIADDCLRDVYVRGKYRDVILPMVVLRRLDTLLEPTKDAVLEEVRY  60
            M+++ H+ LVSFIW IADDCLRDVYVRGKYRDVILPMVVLRRLDTLLEP+K+AVLEEVR+
Sbjct  1    MDHSVHNKLVSFIWSIADDCLRDVYVRGKYRDVILPMVVLRRLDTLLEPSKEAVLEEVRF  60

Query  61   QKEDIGVTELDDEPLKDASGYVFFNTSHWTLKKLYNTATNNQQILLANIEDYLDGFSDNV  120
            QKE++   ELDD PL  +SGYVF+NTS WTL+ L++TATNNQQILLAN+EDYL+GFS+NV
Sbjct  61   QKEEMNEIELDDAPLCATSGYVFYNTSKWTLQTLFSTATNNQQILLANFEDYLNGFSENV  120

Query  121  KEIIGRFNLFEQMRHMAEKQVLLDVIEKFVSPWVNLTPNDIEDPEGNTLPGLSNLGMGYV  180
            KEI+  FNL  Q+RHMA K+VLLDV+EKFVSP +NLTP   EDPEGN LP+LSNLGMGYV
Sbjct  121  KEIVECFNLKAQIRHMAGKNVLLDVVEKFVSPYINLTPAVKEDPEGNKLPALSNLGMGYV  180

Query  181  FEELIRKFNEENNEEAGEHFTPREVIHLMTHLVFDPIKDRLPQILTIYDPACGSGGMLTE  240
            FEELIRKFNEENNEEAGEHFTPREVI+LMTHLVFDPIKD LP  +T+YDPACGSGGMLTE
Sbjct  181  FEELIRKFNEENNEEAGEHFTPREVIELMTHLVFDPIKDNLPLSITVYDPACGSGGMLTE  240

Query  241  AQNYITDADGPFHAHGDVYLYGKEINDETYAICKSDMMIKGNNPENIRIGSTLSTDEFSA  300
            +QN++ +   +  ++ D+YLYGKEINDETYAICKSDMMIKGNNPENIR+GSTLSTDEFS+
Sbjct  241  TQNFVEEKYPA--SNRDIYLYGKEINDETYAICKSDMMIKGNNPENIRVGSTLSTDEFSS  298

Query  301  HRFDFMLSNPPYGKSWNSEVKYIKDGKGVIDPRFQVKLADYWGNVETMDATPRSSDGQLL  360
            +RFDFMLSNPPYGKSW SE K IK+GK V+D RF+VKL DYWG     +A PRSSDGQLL
Sbjct  299  NRFDFMLSNPPYGKSWASEQKHIKEGKEVVDGRFKVKLKDYWGVESEQEAIPRSSDGQLL  358

Query  361  FLMEMISKMKPTSASPLGSRIASVHNGSSLFTGDAGSGESNIRRFIIENDMLDTIIQLPN  420
            FLMEM++KMK+   SPLGSRIASVHNGSSLFTGDAGSGESNIRR+IIENDMLD+I+QLPN
Sbjct  359  FLMEMVTKMKSPQDSPLGSRIASVHNGSSLFTGDAGSGESNIRRYIIENDMLDAIVQLPN  418

Query  421  NLFYNTGITTYIWLLSNAKPEARRGRVQLIDANLMFRKLRKNLGDKNCEFSDEHIQQITE  480
            NLFYNTGITTYIWLL+N KPE R+G+VQLIDA+L+FRKLRKNLG+KNCEFS EHI +I  
Sbjct  419  NLFYNTGITTYIWLLNNNKPENRQGKVQLIDASLLFRKLRKNLGNKNCEFSPEHIAEIVS  478

Query  481  AFLNFAPVERQIDAAGDPEGIAVQVFDNADFGYHKVTIERPDRRRAAFSAERLAPLRFDK  540
            ++L+  +VER ID  GDP GIA QVF N DFGY KV IERPDRR A F A+ + PLRF++
Sbjct  479  TYLENQSVERAIDEKGDPVGIAAQVFKNQDFGYYKVNIERPDRRNAQFRADLIEPLRFEN  538

Query  541  SLREPMEWLYDEHGDQVYQPGFLKEQAKQITAWCEEAGLTlnakakakllDTRYWVKLRD  600
            S RE ME LY E G+QVY++GF+K   K+IT WCEE +++LN  AK+KLLDT+ W+K R 
Sbjct  539  SQREVMEYLYAEYGEQVYDAGFVKGIEKEITKWCEENDISLNKAAKTKLLDTKNWMKQRT  598

Query  601  LLATATQIMGDVGLEETDDFNAFRKVVNAAIKARKIKLGVTEKNAILNAVSWYDETAQKV  660
            L+ +A+Q+   +G E  +DFN F+++V+A + +  +KL+  EK+AIL+AVSWYDE A+KV
Sbjct  599  LVNAASQLHKKIGDEVYNDFNQFKQLVDAELTSLGLKLSAPEKKAILDAVSWYDENAEKV  658

Query  661  IAKKHKLTGAEVEELTTHLGCAAEDLADFGWYRQ-KDGSYLTYESTAELRDAESVALKDN  719
            I K  KL    +++L  +  C  EDL+DFG Y   ++  ++TYES+++LRD+ESV+L ++
Sbjct  659  IKKVAKLKQDKLDDLLENYECELEDLPDFGYYPTGNHNEFVTYESSSDLRDSESVPLEQS  718

Query  720  IHRYFLAEVKPHVEEAWINLDSVKIGYEISFNKYFYRHKPLRSLEEVTQDILALEEKADG  779
            I +YFL EVKPHV+EAW+NL+SVKIGYEISFNKYFYRHKPLRS++EV+++I+ALE+KA+G
Sbjct  719  IYQYFLDEVKPHVDEAWVNLESVKIGYEISFNKYFYRHKPLRSMDEVAKEIIALEQKAEG  778

Query  780  LIADILGVEVAT  791
            LIADILG+ VA 
Sbjct  779  LIADILGISVAK  790

34) hsdM in NC_013211


> EU272902|18|G17|167832524|ACA01834.1|Vibrio_cholerae_Amazonia_3509|-|21794..24175|-|VPI2_0017c|DNA 
methylase HsdM
Length=793

 Score =  943 bits (3574),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 551/792 (70%), Positives = 670/792 (85%), Gaps = 3/792 (0%)

Query  1    MNQTSHSSLVSFIWRIADDCLRDVYVRGKYRDVILPMVVLRRLDTLLEPTKDAVLEEVRY  60
            M+++ H+ LVSFIW IADDCLRDVYVRGKYRDVILPMVVLRRLDTLLEP+K+AVLEEVR+
Sbjct  1    MDHSVHNKLVSFIWSIADDCLRDVYVRGKYRDVILPMVVLRRLDTLLEPSKEAVLEEVRF  60

Query  61   QKEDIGVTELDDEPLKDASGYVFFNTSHWTLKKLYNTATNNQQILLANIEDYLDGFSDNV  120
            QKE++   ELDD PL  +SGYVF+NTS WTL+ L++TATNNQQILLAN+EDYL+GFS+NV
Sbjct  61   QKEEMNEIELDDAPLCATSGYVFYNTSKWTLQTLFSTATNNQQILLANFEDYLNGFSENV  120

Query  121  KEIIGRFNLFEQMRHMAEKQVLLDVIEKFVSPWVNLTPNDIEDPEGNTLPGLSNLGMGYV  180
            KEI+  FNL  Q+RHMA K+VLLDV+EKFVSP +NLTP   EDPEGN LP+LSNLGMGYV
Sbjct  121  KEIVECFNLKAQIRHMAGKNVLLDVVEKFVSPYINLTPAVKEDPEGNKLPALSNLGMGYV  180

Query  181  FEELIRKFNEENNEEAGEHFTPREVIHLMTHLVFDPIKDRLPQILTIYDPACGSGGMLTE  240
            FEELIRKFNEENNEEAGEHFTPREVI+LMTHLVFDPIKD LP  +T+YDPACGSGGMLTE
Sbjct  181  FEELIRKFNEENNEEAGEHFTPREVIELMTHLVFDPIKDNLPLSITVYDPACGSGGMLTE  240

Query  241  AQNYITDADGPFHAHGDVYLYGKEINDETYAICKSDMMIKGNNPENIRIGSTLSTDEFSA  300
            +QN++ +   +  ++ D+YLYGKEINDETYAICKSDMMIKGNNPENIR+GSTLSTDEFS+
Sbjct  241  TQNFVEEKYPA--SNRDIYLYGKEINDETYAICKSDMMIKGNNPENIRVGSTLSTDEFSS  298

Query  301  HRFDFMLSNPPYGKSWNSEVKYIKDGKGVIDPRFQVKLADYWGNVETMDATPRSSDGQLL  360
            +RFDFMLSNPPYGKSW SE K IK+GK V+D RF+VKL DYWG     +A PRSSDGQLL
Sbjct  299  NRFDFMLSNPPYGKSWASEQKHIKEGKEVVDGRFKVKLKDYWGVESEQEAIPRSSDGQLL  358

Query  361  FLMEMISKMKPTSASPLGSRIASVHNGSSLFTGDAGSGESNIRRFIIENDMLDTIIQLPN  420
            FLMEM++KMK+   SPLGSRIASVHNGSSLFTGDAGSGESNIRR+IIENDMLD+I+QLPN
Sbjct  359  FLMEMVTKMKSPQDSPLGSRIASVHNGSSLFTGDAGSGESNIRRYIIENDMLDAIVQLPN  418

Query  421  NLFYNTGITTYIWLLSNAKPEARRGRVQLIDANLMFRKLRKNLGDKNCEFSDEHIQQITE  480
            NLFYNTGITTYIWLL+N KPE R+G+VQLIDA+L+FRKLRKNLG+KNCEFS EHI +I  
Sbjct  419  NLFYNTGITTYIWLLNNNKPENRQGKVQLIDASLLFRKLRKNLGNKNCEFSPEHIAEIVS  478

Query  481  AFLNFAPVERQIDAAGDPEGIAVQVFDNADFGYHKVTIERPDRRRAAFSAERLAPLRFDK  540
            ++L+  +VER ID  GDP GIA QVF N DFGY KV IERPDRR A F A+ + PLRF++
Sbjct  479  TYLENQSVERAIDEKGDPVGIAAQVFKNQDFGYYKVNIERPDRRNAQFRADLIEPLRFEN  538

Query  541  SLREPMEWLYDEHGDQVYQPGFLKEQAKQITAWCEEAGLTlnakakakllDTRYWVKLRD  600
            S RE ME LY E G+QVY++GF+K   K+IT WCEE +++LN  AK+KLLDT+ W+K R 
Sbjct  539  SQREVMEYLYAEYGEQVYDAGFVKGIEKEITKWCEENDISLNKAAKTKLLDTKNWMKQRT  598

Query  601  LLATATQIMGDVGLEETDDFNAFRKVVNAAIKARKIKLGVTEKNAILNAVSWYDETAQKV  660
            L+ +A+Q+   +G E  +DFN F+++V+A + +  +KL+  EK+AIL+AVSWYDE A+KV
Sbjct  599  LVNAASQLHKKIGDEVYNDFNQFKQLVDAELTSLGLKLSAPEKKAILDAVSWYDENAEKV  658

Query  661  IAKKHKLTGAEVEELTTHLGCAAEDLADFGWYRQ-KDGSYLTYESTAELRDAESVALKDN  719
            I K  KL    +++L  +  C  EDL+DFG Y   ++  ++TYES+++LRD+ESV+L ++
Sbjct  659  IKKVAKLKQDKLDDLLENYECELEDLPDFGYYPTGNHNEFVTYESSSDLRDSESVPLEQS  718

Query  720  IHRYFLAEVKPHVEEAWINLDSVKIGYEISFNKYFYRHKPLRSLEEVTQDILALEEKADG  779
            I +YFL EVKPHV+EAW+NL+SVKIGYEISFNKYFYRHKPLRS++EV+++I+ALE+KA+G
Sbjct  719  IYQYFLDEVKPHVDEAWVNLESVKIGYEISFNKYFYRHKPLRSMDEVAKEIIALEQKAEG  778

Query  780  LIADILGVEVAT  791
            LIADILG+ VA 
Sbjct  779  LIADILGISVAK  790

35) hsdM in NC_017118


> EU272902|18|G17|167832524|ACA01834.1|Vibrio_cholerae_Amazonia_3509|-|21794..24175|-|VPI2_0017c|DNA 
methylase HsdM
Length=793

 Score =  943 bits (3574),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 551/792 (70%), Positives = 670/792 (85%), Gaps = 3/792 (0%)

Query  1    MNQTSHSSLVSFIWRIADDCLRDVYVRGKYRDVILPMVVLRRLDTLLEPTKDAVLEEVRY  60
            M+++ H+ LVSFIW IADDCLRDVYVRGKYRDVILPMVVLRRLDTLLEP+K+AVLEEVR+
Sbjct  1    MDHSVHNKLVSFIWSIADDCLRDVYVRGKYRDVILPMVVLRRLDTLLEPSKEAVLEEVRF  60

Query  61   QKEDIGVTELDDEPLKDASGYVFFNTSHWTLKKLYNTATNNQQILLANIEDYLDGFSDNV  120
            QKE++   ELDD PL  +SGYVF+NTS WTL+ L++TATNNQQILLAN+EDYL+GFS+NV
Sbjct  61   QKEEMNEIELDDAPLCATSGYVFYNTSKWTLQTLFSTATNNQQILLANFEDYLNGFSENV  120

Query  121  KEIIGRFNLFEQMRHMAEKQVLLDVIEKFVSPWVNLTPNDIEDPEGNTLPGLSNLGMGYV  180
            KEI+  FNL  Q+RHMA K+VLLDV+EKFVSP +NLTP   EDPEGN LP+LSNLGMGYV
Sbjct  121  KEIVECFNLKAQIRHMAGKNVLLDVVEKFVSPYINLTPAVKEDPEGNKLPALSNLGMGYV  180

Query  181  FEELIRKFNEENNEEAGEHFTPREVIHLMTHLVFDPIKDRLPQILTIYDPACGSGGMLTE  240
            FEELIRKFNEENNEEAGEHFTPREVI+LMTHLVFDPIKD LP  +T+YDPACGSGGMLTE
Sbjct  181  FEELIRKFNEENNEEAGEHFTPREVIELMTHLVFDPIKDNLPLSITVYDPACGSGGMLTE  240

Query  241  AQNYITDADGPFHAHGDVYLYGKEINDETYAICKSDMMIKGNNPENIRIGSTLSTDEFSA  300
            +QN++ +   +  ++ D+YLYGKEINDETYAICKSDMMIKGNNPENIR+GSTLSTDEFS+
Sbjct  241  TQNFVEEKYPA--SNRDIYLYGKEINDETYAICKSDMMIKGNNPENIRVGSTLSTDEFSS  298

Query  301  HRFDFMLSNPPYGKSWNSEVKYIKDGKGVIDPRFQVKLADYWGNVETMDATPRSSDGQLL  360
            +RFDFMLSNPPYGKSW SE K IK+GK V+D RF+VKL DYWG     +A PRSSDGQLL
Sbjct  299  NRFDFMLSNPPYGKSWASEQKHIKEGKEVVDGRFKVKLKDYWGVESEQEAIPRSSDGQLL  358

Query  361  FLMEMISKMKPTSASPLGSRIASVHNGSSLFTGDAGSGESNIRRFIIENDMLDTIIQLPN  420
            FLMEM++KMK+   SPLGSRIASVHNGSSLFTGDAGSGESNIRR+IIENDMLD+I+QLPN
Sbjct  359  FLMEMVTKMKSPQDSPLGSRIASVHNGSSLFTGDAGSGESNIRRYIIENDMLDAIVQLPN  418

Query  421  NLFYNTGITTYIWLLSNAKPEARRGRVQLIDANLMFRKLRKNLGDKNCEFSDEHIQQITE  480
            NLFYNTGITTYIWLL+N KPE R+G+VQLIDA+L+FRKLRKNLG+KNCEFS EHI +I  
Sbjct  419  NLFYNTGITTYIWLLNNNKPENRQGKVQLIDASLLFRKLRKNLGNKNCEFSPEHIAEIVS  478

Query  481  AFLNFAPVERQIDAAGDPEGIAVQVFDNADFGYHKVTIERPDRRRAAFSAERLAPLRFDK  540
            ++L+  +VER ID  GDP GIA QVF N DFGY KV IERPDRR A F A+ + PLRF++
Sbjct  479  TYLENQSVERAIDEKGDPVGIAAQVFKNQDFGYYKVNIERPDRRNAQFRADLIEPLRFEN  538

Query  541  SLREPMEWLYDEHGDQVYQPGFLKEQAKQITAWCEEAGLTlnakakakllDTRYWVKLRD  600
            S RE ME LY E G+QVY++GF+K   K+IT WCEE +++LN  AK+KLLDT+ W+K R 
Sbjct  539  SQREVMEYLYAEYGEQVYDAGFVKGIEKEITKWCEENDISLNKAAKTKLLDTKNWMKQRT  598

Query  601  LLATATQIMGDVGLEETDDFNAFRKVVNAAIKARKIKLGVTEKNAILNAVSWYDETAQKV  660
            L+ +A+Q+   +G E  +DFN F+++V+A + +  +KL+  EK+AIL+AVSWYDE A+KV
Sbjct  599  LVNAASQLHKKIGDEVYNDFNQFKQLVDAELTSLGLKLSAPEKKAILDAVSWYDENAEKV  658

Query  661  IAKKHKLTGAEVEELTTHLGCAAEDLADFGWYRQ-KDGSYLTYESTAELRDAESVALKDN  719
            I K  KL    +++L  +  C  EDL+DFG Y   ++  ++TYES+++LRD+ESV+L ++
Sbjct  659  IKKVAKLKQDKLDDLLENYECELEDLPDFGYYPTGNHNEFVTYESSSDLRDSESVPLEQS  718

Query  720  IHRYFLAEVKPHVEEAWINLDSVKIGYEISFNKYFYRHKPLRSLEEVTQDILALEEKADG  779
            I +YFL EVKPHV+EAW+NL+SVKIGYEISFNKYFYRHKPLRS++EV+++I+ALE+KA+G
Sbjct  719  IYQYFLDEVKPHVDEAWVNLESVKIGYEISFNKYFYRHKPLRSMDEVAKEIIALEQKAEG  778

Query  780  LIADILGVEVAT  791
            LIADILG+ VA 
Sbjct  779  LIADILGISVAK  790

36) hsdM in NC_017122


> EU272902|18|G17|167832524|ACA01834.1|Vibrio_cholerae_Amazonia_3509|-|21794..24175|-|VPI2_0017c|DNA 
methylase HsdM
Length=793

 Score =  943 bits (3574),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 551/792 (70%), Positives = 670/792 (85%), Gaps = 3/792 (0%)

Query  1    MNQTSHSSLVSFIWRIADDCLRDVYVRGKYRDVILPMVVLRRLDTLLEPTKDAVLEEVRY  60
            M+++ H+ LVSFIW IADDCLRDVYVRGKYRDVILPMVVLRRLDTLLEP+K+AVLEEVR+
Sbjct  1    MDHSVHNKLVSFIWSIADDCLRDVYVRGKYRDVILPMVVLRRLDTLLEPSKEAVLEEVRF  60

Query  61   QKEDIGVTELDDEPLKDASGYVFFNTSHWTLKKLYNTATNNQQILLANIEDYLDGFSDNV  120
            QKE++   ELDD PL  +SGYVF+NTS WTL+ L++TATNNQQILLAN+EDYL+GFS+NV
Sbjct  61   QKEEMNEIELDDAPLCATSGYVFYNTSKWTLQTLFSTATNNQQILLANFEDYLNGFSENV  120

Query  121  KEIIGRFNLFEQMRHMAEKQVLLDVIEKFVSPWVNLTPNDIEDPEGNTLPGLSNLGMGYV  180
            KEI+  FNL  Q+RHMA K+VLLDV+EKFVSP +NLTP   EDPEGN LP+LSNLGMGYV
Sbjct  121  KEIVECFNLKAQIRHMAGKNVLLDVVEKFVSPYINLTPAVKEDPEGNKLPALSNLGMGYV  180

Query  181  FEELIRKFNEENNEEAGEHFTPREVIHLMTHLVFDPIKDRLPQILTIYDPACGSGGMLTE  240
            FEELIRKFNEENNEEAGEHFTPREVI+LMTHLVFDPIKD LP  +T+YDPACGSGGMLTE
Sbjct  181  FEELIRKFNEENNEEAGEHFTPREVIELMTHLVFDPIKDNLPLSITVYDPACGSGGMLTE  240

Query  241  AQNYITDADGPFHAHGDVYLYGKEINDETYAICKSDMMIKGNNPENIRIGSTLSTDEFSA  300
            +QN++ +   +  ++ D+YLYGKEINDETYAICKSDMMIKGNNPENIR+GSTLSTDEFS+
Sbjct  241  TQNFVEEKYPA--SNRDIYLYGKEINDETYAICKSDMMIKGNNPENIRVGSTLSTDEFSS  298

Query  301  HRFDFMLSNPPYGKSWNSEVKYIKDGKGVIDPRFQVKLADYWGNVETMDATPRSSDGQLL  360
            +RFDFMLSNPPYGKSW SE K IK+GK V+D RF+VKL DYWG     +A PRSSDGQLL
Sbjct  299  NRFDFMLSNPPYGKSWASEQKHIKEGKEVVDGRFKVKLKDYWGVESEQEAIPRSSDGQLL  358

Query  361  FLMEMISKMKPTSASPLGSRIASVHNGSSLFTGDAGSGESNIRRFIIENDMLDTIIQLPN  420
            FLMEM++KMK+   SPLGSRIASVHNGSSLFTGDAGSGESNIRR+IIENDMLD+I+QLPN
Sbjct  359  FLMEMVTKMKSPQDSPLGSRIASVHNGSSLFTGDAGSGESNIRRYIIENDMLDAIVQLPN  418

Query  421  NLFYNTGITTYIWLLSNAKPEARRGRVQLIDANLMFRKLRKNLGDKNCEFSDEHIQQITE  480
            NLFYNTGITTYIWLL+N KPE R+G+VQLIDA+L+FRKLRKNLG+KNCEFS EHI +I  
Sbjct  419  NLFYNTGITTYIWLLNNNKPENRQGKVQLIDASLLFRKLRKNLGNKNCEFSPEHIAEIVS  478

Query  481  AFLNFAPVERQIDAAGDPEGIAVQVFDNADFGYHKVTIERPDRRRAAFSAERLAPLRFDK  540
            ++L+  +VER ID  GDP GIA QVF N DFGY KV IERPDRR A F A+ + PLRF++
Sbjct  479  TYLENQSVERAIDEKGDPVGIAAQVFKNQDFGYYKVNIERPDRRNAQFRADLIEPLRFEN  538

Query  541  SLREPMEWLYDEHGDQVYQPGFLKEQAKQITAWCEEAGLTlnakakakllDTRYWVKLRD  600
            S RE ME LY E G+QVY++GF+K   K+IT WCEE +++LN  AK+KLLDT+ W+K R 
Sbjct  539  SQREVMEYLYAEYGEQVYDAGFVKGIEKEITKWCEENDISLNKAAKTKLLDTKNWMKQRT  598

Query  601  LLATATQIMGDVGLEETDDFNAFRKVVNAAIKARKIKLGVTEKNAILNAVSWYDETAQKV  660
            L+ +A+Q+   +G E  +DFN F+++V+A + +  +KL+  EK+AIL+AVSWYDE A+KV
Sbjct  599  LVNAASQLHKKIGDEVYNDFNQFKQLVDAELTSLGLKLSAPEKKAILDAVSWYDENAEKV  658

Query  661  IAKKHKLTGAEVEELTTHLGCAAEDLADFGWYRQ-KDGSYLTYESTAELRDAESVALKDN  719
            I K  KL    +++L  +  C  EDL+DFG Y   ++  ++TYES+++LRD+ESV+L ++
Sbjct  659  IKKVAKLKQDKLDDLLENYECELEDLPDFGYYPTGNHNEFVTYESSSDLRDSESVPLEQS  718

Query  720  IHRYFLAEVKPHVEEAWINLDSVKIGYEISFNKYFYRHKPLRSLEEVTQDILALEEKADG  779
            I +YFL EVKPHV+EAW+NL+SVKIGYEISFNKYFYRHKPLRS++EV+++I+ALE+KA+G
Sbjct  719  IYQYFLDEVKPHVDEAWVNLESVKIGYEISFNKYFYRHKPLRSMDEVAKEIIALEQKAEG  778

Query  780  LIADILGVEVAT  791
            LIADILG+ VA 
Sbjct  779  LIADILGISVAK  790

37) hsdM in NC_017113


> EU272902|18|G17|167832524|ACA01834.1|Vibrio_cholerae_Amazonia_3509|-|21794..24175|-|VPI2_0017c|DNA 
methylase HsdM
Length=793

 Score =  943 bits (3574),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 551/792 (70%), Positives = 670/792 (85%), Gaps = 3/792 (0%)

Query  1    MNQTSHSSLVSFIWRIADDCLRDVYVRGKYRDVILPMVVLRRLDTLLEPTKDAVLEEVRY  60
            M+++ H+ LVSFIW IADDCLRDVYVRGKYRDVILPMVVLRRLDTLLEP+K+AVLEEVR+
Sbjct  1    MDHSVHNKLVSFIWSIADDCLRDVYVRGKYRDVILPMVVLRRLDTLLEPSKEAVLEEVRF  60

Query  61   QKEDIGVTELDDEPLKDASGYVFFNTSHWTLKKLYNTATNNQQILLANIEDYLDGFSDNV  120
            QKE++   ELDD PL  +SGYVF+NTS WTL+ L++TATNNQQILLAN+EDYL+GFS+NV
Sbjct  61   QKEEMNEIELDDAPLCATSGYVFYNTSKWTLQTLFSTATNNQQILLANFEDYLNGFSENV  120

Query  121  KEIIGRFNLFEQMRHMAEKQVLLDVIEKFVSPWVNLTPNDIEDPEGNTLPGLSNLGMGYV  180
            KEI+  FNL  Q+RHMA K+VLLDV+EKFVSP +NLTP   EDPEGN LP+LSNLGMGYV
Sbjct  121  KEIVECFNLKAQIRHMAGKNVLLDVVEKFVSPYINLTPAVKEDPEGNKLPALSNLGMGYV  180

Query  181  FEELIRKFNEENNEEAGEHFTPREVIHLMTHLVFDPIKDRLPQILTIYDPACGSGGMLTE  240
            FEELIRKFNEENNEEAGEHFTPREVI+LMTHLVFDPIKD LP  +T+YDPACGSGGMLTE
Sbjct  181  FEELIRKFNEENNEEAGEHFTPREVIELMTHLVFDPIKDNLPLSITVYDPACGSGGMLTE  240

Query  241  AQNYITDADGPFHAHGDVYLYGKEINDETYAICKSDMMIKGNNPENIRIGSTLSTDEFSA  300
            +QN++ +   +  ++ D+YLYGKEINDETYAICKSDMMIKGNNPENIR+GSTLSTDEFS+
Sbjct  241  TQNFVEEKYPA--SNRDIYLYGKEINDETYAICKSDMMIKGNNPENIRVGSTLSTDEFSS  298

Query  301  HRFDFMLSNPPYGKSWNSEVKYIKDGKGVIDPRFQVKLADYWGNVETMDATPRSSDGQLL  360
            +RFDFMLSNPPYGKSW SE K IK+GK V+D RF+VKL DYWG     +A PRSSDGQLL
Sbjct  299  NRFDFMLSNPPYGKSWASEQKHIKEGKEVVDGRFKVKLKDYWGVESEQEAIPRSSDGQLL  358

Query  361  FLMEMISKMKPTSASPLGSRIASVHNGSSLFTGDAGSGESNIRRFIIENDMLDTIIQLPN  420
            FLMEM++KMK+   SPLGSRIASVHNGSSLFTGDAGSGESNIRR+IIENDMLD+I+QLPN
Sbjct  359  FLMEMVTKMKSPQDSPLGSRIASVHNGSSLFTGDAGSGESNIRRYIIENDMLDAIVQLPN  418

Query  421  NLFYNTGITTYIWLLSNAKPEARRGRVQLIDANLMFRKLRKNLGDKNCEFSDEHIQQITE  480
            NLFYNTGITTYIWLL+N KPE R+G+VQLIDA+L+FRKLRKNLG+KNCEFS EHI +I  
Sbjct  419  NLFYNTGITTYIWLLNNNKPENRQGKVQLIDASLLFRKLRKNLGNKNCEFSPEHIAEIVS  478

Query  481  AFLNFAPVERQIDAAGDPEGIAVQVFDNADFGYHKVTIERPDRRRAAFSAERLAPLRFDK  540
            ++L+  +VER ID  GDP GIA QVF N DFGY KV IERPDRR A F A+ + PLRF++
Sbjct  479  TYLENQSVERAIDEKGDPVGIAAQVFKNQDFGYYKVNIERPDRRNAQFRADLIEPLRFEN  538

Query  541  SLREPMEWLYDEHGDQVYQPGFLKEQAKQITAWCEEAGLTlnakakakllDTRYWVKLRD  600
            S RE ME LY E G+QVY++GF+K   K+IT WCEE +++LN  AK+KLLDT+ W+K R 
Sbjct  539  SQREVMEYLYAEYGEQVYDAGFVKGIEKEITKWCEENDISLNKAAKTKLLDTKNWMKQRT  598

Query  601  LLATATQIMGDVGLEETDDFNAFRKVVNAAIKARKIKLGVTEKNAILNAVSWYDETAQKV  660
            L+ +A+Q+   +G E  +DFN F+++V+A + +  +KL+  EK+AIL+AVSWYDE A+KV
Sbjct  599  LVNAASQLHKKIGDEVYNDFNQFKQLVDAELTSLGLKLSAPEKKAILDAVSWYDENAEKV  658

Query  661  IAKKHKLTGAEVEELTTHLGCAAEDLADFGWYRQ-KDGSYLTYESTAELRDAESVALKDN  719
            I K  KL    +++L  +  C  EDL+DFG Y   ++  ++TYES+++LRD+ESV+L ++
Sbjct  659  IKKVAKLKQDKLDDLLENYECELEDLPDFGYYPTGNHNEFVTYESSSDLRDSESVPLEQS  718

Query  720  IHRYFLAEVKPHVEEAWINLDSVKIGYEISFNKYFYRHKPLRSLEEVTQDILALEEKADG  779
            I +YFL EVKPHV+EAW+NL+SVKIGYEISFNKYFYRHKPLRS++EV+++I+ALE+KA+G
Sbjct  719  IYQYFLDEVKPHVDEAWVNLESVKIGYEISFNKYFYRHKPLRSMDEVAKEIIALEQKAEG  778

Query  780  LIADILGVEVAT  791
            LIADILG+ VA 
Sbjct  779  LIADILGISVAK  790

38) hsdM in NC_017126


> EU272902|18|G17|167832524|ACA01834.1|Vibrio_cholerae_Amazonia_3509|-|21794..24175|-|VPI2_0017c|DNA 
methylase HsdM
Length=793

 Score =  943 bits (3574),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 551/792 (70%), Positives = 670/792 (85%), Gaps = 3/792 (0%)

Query  1    MNQTSHSSLVSFIWRIADDCLRDVYVRGKYRDVILPMVVLRRLDTLLEPTKDAVLEEVRY  60
            M+++ H+ LVSFIW IADDCLRDVYVRGKYRDVILPMVVLRRLDTLLEP+K+AVLEEVR+
Sbjct  1    MDHSVHNKLVSFIWSIADDCLRDVYVRGKYRDVILPMVVLRRLDTLLEPSKEAVLEEVRF  60

Query  61   QKEDIGVTELDDEPLKDASGYVFFNTSHWTLKKLYNTATNNQQILLANIEDYLDGFSDNV  120
            QKE++   ELDD PL  +SGYVF+NTS WTL+ L++TATNNQQILLAN+EDYL+GFS+NV
Sbjct  61   QKEEMNEIELDDAPLCATSGYVFYNTSKWTLQTLFSTATNNQQILLANFEDYLNGFSENV  120

Query  121  KEIIGRFNLFEQMRHMAEKQVLLDVIEKFVSPWVNLTPNDIEDPEGNTLPGLSNLGMGYV  180
            KEI+  FNL  Q+RHMA K+VLLDV+EKFVSP +NLTP   EDPEGN LP+LSNLGMGYV
Sbjct  121  KEIVECFNLKAQIRHMAGKNVLLDVVEKFVSPYINLTPAVKEDPEGNKLPALSNLGMGYV  180

Query  181  FEELIRKFNEENNEEAGEHFTPREVIHLMTHLVFDPIKDRLPQILTIYDPACGSGGMLTE  240
            FEELIRKFNEENNEEAGEHFTPREVI+LMTHLVFDPIKD LP  +T+YDPACGSGGMLTE
Sbjct  181  FEELIRKFNEENNEEAGEHFTPREVIELMTHLVFDPIKDNLPLSITVYDPACGSGGMLTE  240

Query  241  AQNYITDADGPFHAHGDVYLYGKEINDETYAICKSDMMIKGNNPENIRIGSTLSTDEFSA  300
            +QN++ +   +  ++ D+YLYGKEINDETYAICKSDMMIKGNNPENIR+GSTLSTDEFS+
Sbjct  241  TQNFVEEKYPA--SNRDIYLYGKEINDETYAICKSDMMIKGNNPENIRVGSTLSTDEFSS  298

Query  301  HRFDFMLSNPPYGKSWNSEVKYIKDGKGVIDPRFQVKLADYWGNVETMDATPRSSDGQLL  360
            +RFDFMLSNPPYGKSW SE K IK+GK V+D RF+VKL DYWG     +A PRSSDGQLL
Sbjct  299  NRFDFMLSNPPYGKSWASEQKHIKEGKEVVDGRFKVKLKDYWGVESEQEAIPRSSDGQLL  358

Query  361  FLMEMISKMKPTSASPLGSRIASVHNGSSLFTGDAGSGESNIRRFIIENDMLDTIIQLPN  420
            FLMEM++KMK+   SPLGSRIASVHNGSSLFTGDAGSGESNIRR+IIENDMLD+I+QLPN
Sbjct  359  FLMEMVTKMKSPQDSPLGSRIASVHNGSSLFTGDAGSGESNIRRYIIENDMLDAIVQLPN  418

Query  421  NLFYNTGITTYIWLLSNAKPEARRGRVQLIDANLMFRKLRKNLGDKNCEFSDEHIQQITE  480
            NLFYNTGITTYIWLL+N KPE R+G+VQLIDA+L+FRKLRKNLG+KNCEFS EHI +I  
Sbjct  419  NLFYNTGITTYIWLLNNNKPENRQGKVQLIDASLLFRKLRKNLGNKNCEFSPEHIAEIVS  478

Query  481  AFLNFAPVERQIDAAGDPEGIAVQVFDNADFGYHKVTIERPDRRRAAFSAERLAPLRFDK  540
            ++L+  +VER ID  GDP GIA QVF N DFGY KV IERPDRR A F A+ + PLRF++
Sbjct  479  TYLENQSVERAIDEKGDPVGIAAQVFKNQDFGYYKVNIERPDRRNAQFRADLIEPLRFEN  538

Query  541  SLREPMEWLYDEHGDQVYQPGFLKEQAKQITAWCEEAGLTlnakakakllDTRYWVKLRD  600
            S RE ME LY E G+QVY++GF+K   K+IT WCEE +++LN  AK+KLLDT+ W+K R 
Sbjct  539  SQREVMEYLYAEYGEQVYDAGFVKGIEKEITKWCEENDISLNKAAKTKLLDTKNWMKQRT  598

Query  601  LLATATQIMGDVGLEETDDFNAFRKVVNAAIKARKIKLGVTEKNAILNAVSWYDETAQKV  660
            L+ +A+Q+   +G E  +DFN F+++V+A + +  +KL+  EK+AIL+AVSWYDE A+KV
Sbjct  599  LVNAASQLHKKIGDEVYNDFNQFKQLVDAELTSLGLKLSAPEKKAILDAVSWYDENAEKV  658

Query  661  IAKKHKLTGAEVEELTTHLGCAAEDLADFGWYRQ-KDGSYLTYESTAELRDAESVALKDN  719
            I K  KL    +++L  +  C  EDL+DFG Y   ++  ++TYES+++LRD+ESV+L ++
Sbjct  659  IKKVAKLKQDKLDDLLENYECELEDLPDFGYYPTGNHNEFVTYESSSDLRDSESVPLEQS  718

Query  720  IHRYFLAEVKPHVEEAWINLDSVKIGYEISFNKYFYRHKPLRSLEEVTQDILALEEKADG  779
            I +YFL EVKPHV+EAW+NL+SVKIGYEISFNKYFYRHKPLRS++EV+++I+ALE+KA+G
Sbjct  719  IYQYFLDEVKPHVDEAWVNLESVKIGYEISFNKYFYRHKPLRSMDEVAKEIIALEQKAEG  778

Query  780  LIADILGVEVAT  791
            LIADILG+ VA 
Sbjct  779  LIADILGISVAK  790

39) hsdM in NC_017131


> EU272902|18|G17|167832524|ACA01834.1|Vibrio_cholerae_Amazonia_3509|-|21794..24175|-|VPI2_0017c|DNA 
methylase HsdM
Length=793

 Score =  943 bits (3574),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 551/792 (70%), Positives = 670/792 (85%), Gaps = 3/792 (0%)

Query  1    MNQTSHSSLVSFIWRIADDCLRDVYVRGKYRDVILPMVVLRRLDTLLEPTKDAVLEEVRY  60
            M+++ H+ LVSFIW IADDCLRDVYVRGKYRDVILPMVVLRRLDTLLEP+K+AVLEEVR+
Sbjct  1    MDHSVHNKLVSFIWSIADDCLRDVYVRGKYRDVILPMVVLRRLDTLLEPSKEAVLEEVRF  60

Query  61   QKEDIGVTELDDEPLKDASGYVFFNTSHWTLKKLYNTATNNQQILLANIEDYLDGFSDNV  120
            QKE++   ELDD PL  +SGYVF+NTS WTL+ L++TATNNQQILLAN+EDYL+GFS+NV
Sbjct  61   QKEEMNEIELDDAPLCATSGYVFYNTSKWTLQTLFSTATNNQQILLANFEDYLNGFSENV  120

Query  121  KEIIGRFNLFEQMRHMAEKQVLLDVIEKFVSPWVNLTPNDIEDPEGNTLPGLSNLGMGYV  180
            KEI+  FNL  Q+RHMA K+VLLDV+EKFVSP +NLTP   EDPEGN LP+LSNLGMGYV
Sbjct  121  KEIVECFNLKAQIRHMAGKNVLLDVVEKFVSPYINLTPAVKEDPEGNKLPALSNLGMGYV  180

Query  181  FEELIRKFNEENNEEAGEHFTPREVIHLMTHLVFDPIKDRLPQILTIYDPACGSGGMLTE  240
            FEELIRKFNEENNEEAGEHFTPREVI+LMTHLVFDPIKD LP  +T+YDPACGSGGMLTE
Sbjct  181  FEELIRKFNEENNEEAGEHFTPREVIELMTHLVFDPIKDNLPLSITVYDPACGSGGMLTE  240

Query  241  AQNYITDADGPFHAHGDVYLYGKEINDETYAICKSDMMIKGNNPENIRIGSTLSTDEFSA  300
            +QN++ +   +  ++ D+YLYGKEINDETYAICKSDMMIKGNNPENIR+GSTLSTDEFS+
Sbjct  241  TQNFVEEKYPA--SNRDIYLYGKEINDETYAICKSDMMIKGNNPENIRVGSTLSTDEFSS  298

Query  301  HRFDFMLSNPPYGKSWNSEVKYIKDGKGVIDPRFQVKLADYWGNVETMDATPRSSDGQLL  360
            +RFDFMLSNPPYGKSW SE K IK+GK V+D RF+VKL DYWG     +A PRSSDGQLL
Sbjct  299  NRFDFMLSNPPYGKSWASEQKHIKEGKEVVDGRFKVKLKDYWGVESEQEAIPRSSDGQLL  358

Query  361  FLMEMISKMKPTSASPLGSRIASVHNGSSLFTGDAGSGESNIRRFIIENDMLDTIIQLPN  420
            FLMEM++KMK+   SPLGSRIASVHNGSSLFTGDAGSGESNIRR+IIENDMLD+I+QLPN
Sbjct  359  FLMEMVTKMKSPQDSPLGSRIASVHNGSSLFTGDAGSGESNIRRYIIENDMLDAIVQLPN  418

Query  421  NLFYNTGITTYIWLLSNAKPEARRGRVQLIDANLMFRKLRKNLGDKNCEFSDEHIQQITE  480
            NLFYNTGITTYIWLL+N KPE R+G+VQLIDA+L+FRKLRKNLG+KNCEFS EHI +I  
Sbjct  419  NLFYNTGITTYIWLLNNNKPENRQGKVQLIDASLLFRKLRKNLGNKNCEFSPEHIAEIVS  478

Query  481  AFLNFAPVERQIDAAGDPEGIAVQVFDNADFGYHKVTIERPDRRRAAFSAERLAPLRFDK  540
            ++L+  +VER ID  GDP GIA QVF N DFGY KV IERPDRR A F A+ + PLRF++
Sbjct  479  TYLENQSVERAIDEKGDPVGIAAQVFKNQDFGYYKVNIERPDRRNAQFRADLIEPLRFEN  538

Query  541  SLREPMEWLYDEHGDQVYQPGFLKEQAKQITAWCEEAGLTlnakakakllDTRYWVKLRD  600
            S RE ME LY E G+QVY++GF+K   K+IT WCEE +++LN  AK+KLLDT+ W+K R 
Sbjct  539  SQREVMEYLYAEYGEQVYDAGFVKGIEKEITKWCEENDISLNKAAKTKLLDTKNWMKQRT  598

Query  601  LLATATQIMGDVGLEETDDFNAFRKVVNAAIKARKIKLGVTEKNAILNAVSWYDETAQKV  660
            L+ +A+Q+   +G E  +DFN F+++V+A + +  +KL+  EK+AIL+AVSWYDE A+KV
Sbjct  599  LVNAASQLHKKIGDEVYNDFNQFKQLVDAELTSLGLKLSAPEKKAILDAVSWYDENAEKV  658

Query  661  IAKKHKLTGAEVEELTTHLGCAAEDLADFGWYRQ-KDGSYLTYESTAELRDAESVALKDN  719
            I K  KL    +++L  +  C  EDL+DFG Y   ++  ++TYES+++LRD+ESV+L ++
Sbjct  659  IKKVAKLKQDKLDDLLENYECELEDLPDFGYYPTGNHNEFVTYESSSDLRDSESVPLEQS  718

Query  720  IHRYFLAEVKPHVEEAWINLDSVKIGYEISFNKYFYRHKPLRSLEEVTQDILALEEKADG  779
            I +YFL EVKPHV+EAW+NL+SVKIGYEISFNKYFYRHKPLRS++EV+++I+ALE+KA+G
Sbjct  719  IYQYFLDEVKPHVDEAWVNLESVKIGYEISFNKYFYRHKPLRSMDEVAKEIIALEQKAEG  778

Query  780  LIADILGVEVAT  791
            LIADILG+ VA 
Sbjct  779  LIADILGISVAK  790

40) hsdM in NC_017149


> EU272902|18|G17|167832524|ACA01834.1|Vibrio_cholerae_Amazonia_3509|-|21794..24175|-|VPI2_0017c|DNA 
methylase HsdM
Length=793

 Score =  943 bits (3574),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 551/792 (70%), Positives = 670/792 (85%), Gaps = 3/792 (0%)

Query  1    MNQTSHSSLVSFIWRIADDCLRDVYVRGKYRDVILPMVVLRRLDTLLEPTKDAVLEEVRY  60
            M+++ H+ LVSFIW IADDCLRDVYVRGKYRDVILPMVVLRRLDTLLEP+K+AVLEEVR+
Sbjct  1    MDHSVHNKLVSFIWSIADDCLRDVYVRGKYRDVILPMVVLRRLDTLLEPSKEAVLEEVRF  60

Query  61   QKEDIGVTELDDEPLKDASGYVFFNTSHWTLKKLYNTATNNQQILLANIEDYLDGFSDNV  120
            QKE++   ELDD PL  +SGYVF+NTS WTL+ L++TATNNQQILLAN+EDYL+GFS+NV
Sbjct  61   QKEEMNEIELDDAPLCATSGYVFYNTSKWTLQTLFSTATNNQQILLANFEDYLNGFSENV  120

Query  121  KEIIGRFNLFEQMRHMAEKQVLLDVIEKFVSPWVNLTPNDIEDPEGNTLPGLSNLGMGYV  180
            KEI+  FNL  Q+RHMA K+VLLDV+EKFVSP +NLTP   EDPEGN LP+LSNLGMGYV
Sbjct  121  KEIVECFNLKAQIRHMAGKNVLLDVVEKFVSPYINLTPAVKEDPEGNKLPALSNLGMGYV  180

Query  181  FEELIRKFNEENNEEAGEHFTPREVIHLMTHLVFDPIKDRLPQILTIYDPACGSGGMLTE  240
            FEELIRKFNEENNEEAGEHFTPREVI+LMTHLVFDPIKD LP  +T+YDPACGSGGMLTE
Sbjct  181  FEELIRKFNEENNEEAGEHFTPREVIELMTHLVFDPIKDNLPLSITVYDPACGSGGMLTE  240

Query  241  AQNYITDADGPFHAHGDVYLYGKEINDETYAICKSDMMIKGNNPENIRIGSTLSTDEFSA  300
            +QN++ +   +  ++ D+YLYGKEINDETYAICKSDMMIKGNNPENIR+GSTLSTDEFS+
Sbjct  241  TQNFVEEKYPA--SNRDIYLYGKEINDETYAICKSDMMIKGNNPENIRVGSTLSTDEFSS  298

Query  301  HRFDFMLSNPPYGKSWNSEVKYIKDGKGVIDPRFQVKLADYWGNVETMDATPRSSDGQLL  360
            +RFDFMLSNPPYGKSW SE K IK+GK V+D RF+VKL DYWG     +A PRSSDGQLL
Sbjct  299  NRFDFMLSNPPYGKSWASEQKHIKEGKEVVDGRFKVKLKDYWGVESEQEAIPRSSDGQLL  358

Query  361  FLMEMISKMKPTSASPLGSRIASVHNGSSLFTGDAGSGESNIRRFIIENDMLDTIIQLPN  420
            FLMEM++KMK+   SPLGSRIASVHNGSSLFTGDAGSGESNIRR+IIENDMLD+I+QLPN
Sbjct  359  FLMEMVTKMKSPQDSPLGSRIASVHNGSSLFTGDAGSGESNIRRYIIENDMLDAIVQLPN  418

Query  421  NLFYNTGITTYIWLLSNAKPEARRGRVQLIDANLMFRKLRKNLGDKNCEFSDEHIQQITE  480
            NLFYNTGITTYIWLL+N KPE R+G+VQLIDA+L+FRKLRKNLG+KNCEFS EHI +I  
Sbjct  419  NLFYNTGITTYIWLLNNNKPENRQGKVQLIDASLLFRKLRKNLGNKNCEFSPEHIAEIVS  478

Query  481  AFLNFAPVERQIDAAGDPEGIAVQVFDNADFGYHKVTIERPDRRRAAFSAERLAPLRFDK  540
            ++L+  +VER ID  GDP GIA QVF N DFGY KV IERPDRR A F A+ + PLRF++
Sbjct  479  TYLENQSVERAIDEKGDPVGIAAQVFKNQDFGYYKVNIERPDRRNAQFRADLIEPLRFEN  538

Query  541  SLREPMEWLYDEHGDQVYQPGFLKEQAKQITAWCEEAGLTlnakakakllDTRYWVKLRD  600
            S RE ME LY E G+QVY++GF+K   K+IT WCEE +++LN  AK+KLLDT+ W+K R 
Sbjct  539  SQREVMEYLYAEYGEQVYDAGFVKGIEKEITKWCEENDISLNKAAKTKLLDTKNWMKQRT  598

Query  601  LLATATQIMGDVGLEETDDFNAFRKVVNAAIKARKIKLGVTEKNAILNAVSWYDETAQKV  660
            L+ +A+Q+   +G E  +DFN F+++V+A + +  +KL+  EK+AIL+AVSWYDE A+KV
Sbjct  599  LVNAASQLHKKIGDEVYNDFNQFKQLVDAELTSLGLKLSAPEKKAILDAVSWYDENAEKV  658

Query  661  IAKKHKLTGAEVEELTTHLGCAAEDLADFGWYRQ-KDGSYLTYESTAELRDAESVALKDN  719
            I K  KL    +++L  +  C  EDL+DFG Y   ++  ++TYES+++LRD+ESV+L ++
Sbjct  659  IKKVAKLKQDKLDDLLENYECELEDLPDFGYYPTGNHNEFVTYESSSDLRDSESVPLEQS  718

Query  720  IHRYFLAEVKPHVEEAWINLDSVKIGYEISFNKYFYRHKPLRSLEEVTQDILALEEKADG  779
            I +YFL EVKPHV+EAW+NL+SVKIGYEISFNKYFYRHKPLRS++EV+++I+ALE+KA+G
Sbjct  719  IYQYFLDEVKPHVDEAWVNLESVKIGYEISFNKYFYRHKPLRSMDEVAKEIIALEQKAEG  778

Query  780  LIADILGVEVAT  791
            LIADILG+ VA 
Sbjct  779  LIADILGISVAK  790

41) PSPPH_0107 in NC_005773


> EU272902|18|G17|167832524|ACA01834.1|Vibrio_cholerae_Amazonia_3509|-|21794..24175|-|VPI2_0017c|DNA 
methylase HsdM
Length=793

 Score =  937 bits (3549),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 562/799 (71%), Positives = 675/799 (85%), Gaps = 10/799 (1%)

Query  1    MNHAVHNKLVSFIWSIADDCLRDVYVRGKYRDVILPMVVLRRLDALLEPSKAKVMEELAF  60
            M+H+VHNKLVSFIWSIADDCLRDVYVRGKYRDVILPMVVLRRLD+LLEPSK  V+EE+ F
Sbjct  1    MDHSVHNKLVSFIWSIADDCLRDVYVRGKYRDVILPMVVLRRLDTLLEPSKEAVLEEVRF  60

Query  61   QQGEMSQTELDDSALRSASGYVFYNTSKWTLSQLQKTATNNQQILLNNVEEYLDGFSDNV  120
            Q+ EM++ ELDD++L ++SGYVFYNTSKWTL  L  TATNNQQILL N E+YL+GFS+NV
Sbjct  61   QKEEMNEIELDDAPLCATSGYVFYNTSKWTLQTLFSTATNNQQILLANFEDYLNGFSENV  120

Query  121  KDIVRRFNLKSQMRHMASKDVLLDVLEKFTSPYVNLTPTDIEDPEGNRLPALSNLGMGYV  180
            K+IV  FNLK+Q+RHMA+K+VLLDV+EKF SPY+NLTP+  EDPEGN+LPALSNLGMGYV
Sbjct  121  KEIVECFNLKAQIRHMAGKNVLLDVVEKFVSPYINLTPAVKEDPEGNKLPALSNLGMGYV  180

Query  181  FEELIRKFNEENNEEAGEHFTPREVIELMTHLVFDPIKDSLPPVMTIYDPACGSGGMLTE  240
            FEELIRKFNEENNEEAGEHFTPREVIELMTHLVFDPIKD+LP  +T+YDPACGSGGMLTE
Sbjct  181  FEELIRKFNEENNEEAGEHFTPREVIELMTHLVFDPIKDNLPLSITVYDPACGSGGMLTE  240

Query  241  SQNFIEEKYPDPTTQRDIHLYGKEINDETYAICKSDMMIKGNNPAHIRPGSTLSVDEFAG  300
            +QNF+EEKY  P+++RDI LYGKEINDETYAICKSDMMIKGNNP +IR GSTLS DEF++
Sbjct  241  TQNFVEEKY--PASNRDIYLYGKEINDETYAICKSDMMIKGNNPENIRVGSTLSTDEFSS  298

Query  301  SRFDFMLSNPPYGKSWASEQKFIKDCGEVIDPRFKVSLRDYWDNPEMQDATPRSSDGQLL  360
            +RFDFMLSNPPYGKSWASEQK IK+  EV+D RFKV L+DYW+    Q+A PRSSDGQLL
Sbjct  299  NRFDFMLSNPPYGKSWASEQKHIKEGKEVVDGRFKVKLKDYWGVESEQEAIPRSSDGQLL  358

Query  361  FLMEMVNKMKASGEGSLGSRIASVHNGSSLFTGDAGSGESNIRRHLIENDLLDAIIQLPN  420
            FLMEMV KMK++ +++LGSRIASVHNGSSLFTGDAGSGESNIRR +IEND+LDAI+QLPN
Sbjct  359  FLMEMVTKMKSPQDSPLGSRIASVHNGSSLFTGDAGSGESNIRRYIIENDMLDAIVQLPN  418

Query  421  NLFYNTGITTYIWLLSSNKPVQRRGKVQLIDASLLYRKLRKNLGNKNCEFAPEHIELITQ  480
            NLFYNTGITTYIWLL++NKP +R+GKVQLIDASLL+RKLRKNLGNKNCEF+PEHI  I  
Sbjct  419  NLFYNTGITTYIWLLNNNKPENRQGKVQLIDASLLFRKLRKNLGNKNCEFSPEHIAEIVS  478

Query  481  TYLDLASLDRPAGGD----GIAAQVFDNRDFGYHKVSIERPDRRKAQFSAERIETLRFDK  536
            TYL+  S++R+ +      GIAAQVF N+DFGY KV+IERPDRR+AQF A+ IE LRF++
Sbjct  479  TYLENQSVERAIDEKGDPVGIAAQVFKNQDFGYYKVNIERPDRRNAQFRADLIEPLRFEN  538

Query  537  ALREPMQWIYQQWGEALYQDEALATHEKAILAWCEEQGLELNIKQRKKLLNLETWAKQAL  596
            + RE M+ +Y + GE +Y+   +   EK I  WCEE+++ LN   + KLL+   W KQ  
Sbjct  539  SQREVMEYLYAEYGEQVYDAGFVKGIEKEITKWCEENDISLNKAAKTKLLDTKNWMKQRT  598

Query  597  LVTVANYLMQAIGSDEYDDFNLFAKLVDKVLKQLNKEVGIKLGASERNQVLNAVSWYDEN  656
            LV  A+ L + IG + Y+DFN F +LVD  L  L    G+KL+A+E++ +L+AVSWYDEN
Sbjct  599  LVNAASQLHKKIGDEVYNDFNQFKQLVDAELTSL----GLKLSAPEKKAILDAVSWYDEN  654

Query  657  AVKVLRKVEKFDraelaallerlDCIEADLADFGYYPSDKAGEWITYESNSDLRDSESIP  716
            A KV++KV K+ +  L  LLE  +C   DL+DFGYYP+++  E +TYES+SDLRDSES+P
Sbjct  655  AEKVIKKVAKLKQDKLDDLLENYECELEDLPDFGYYPTGNHNEFVTYESSSDLRDSESVP  714

Query  717  LADSIHHFFKAEVQPHVEEAWINLESVKIGYEISFNKYFYKHQPLRSTDEVAREIIALEQ  776
            L +SI ++F  EV+PHV+EAW+NLESVKIGYEISFNKYFY+H+PLRS DEVA+EIIALEQ
Sbjct  715  LEQSIYQYFLDEVKPHVDEAWVNLESVKIGYEISFNKYFYRHKPLRSMDEVAKEIIALEQ  774

Query  777  QAEGLIAEILGISVDTVSG  795
            +AEGLIA+ILGISV  V G
Sbjct  775  KAEGLIADILGISVAKVQG  793

42) Halhy_4893 in NC_015510


> EU272902|18|G17|167832524|ACA01834.1|Vibrio_cholerae_Amazonia_3509|-|21794..24175|-|VPI2_0017c|DNA 
methylase HsdM
Length=793

 Score =  906 bits (3433),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 542/790 (69%), Positives = 653/790 (83%), Gaps = 5/790 (0%)

Query  1    MNRTVHNKLVSFIWSIADDCLRDVYVRGKYRDVILPMVVLRRLDALLEPTKDAVLEELAF  60
            M+++VHNKLVSFIWSIADDCLRDVYVRGKYRDVILPMVVLRRLD+LLEP+K+AVLEE+ F
Sbjct  1    MDHSVHNKLVSFIWSIADDCLRDVYVRGKYRDVILPMVVLRRLDTLLEPSKEAVLEEVRF  60

Query  61   QRDEAKFTEWDENGLRDASGYVFYNTSKWTLQLLKDTATNNQQILQANFEDYLNGFSPNV  120
            Q++E +  E D+  L  +SGYVFYNTSKWTLQ L  TATNNQQIL ANFEDYLNGFS NV
Sbjct  61   QKEEMNEIELDDAPLCATSGYVFYNTSKWTLQTLFSTATNNQQILLANFEDYLNGFSENV  120

Query  121  KEIIEKFKLKSQVRHMAAKDVLLDVLEKFTSPAINLTPFEKTDPDGRKLPALSNLGMGYV  180
            KEI+E F+LK+Q+RHMA+K+VLLDV+EKF SP INLTP  K DP+G KLPALSNLGMGYV
Sbjct  121  KEIVECFNLKAQIRHMAGKNVLLDVVEKFVSPYINLTPAVKEDPEGNKLPALSNLGMGYV  180

Query  181  FEELIRKFNEENNEEAGEHFTPREVIDLMTHLIFEPVARQLPPVMTIYDPACGSGGMLTE  240
            FEELIRKFNEENNEEAGEHFTPREVI+LMTHL+F+P+  +LP  +T+YDPACGSGGMLTE
Sbjct  181  FEELIRKFNEENNEEAGEHFTPREVIELMTHLVFDPIKDNLPLSITVYDPACGSGGMLTE  240

Query  241  SQNFVKDEEGIIQAKGDVYLYGKEINDETYAICKSDMMIKGNDPENIRVGSTLSTDEFAG  300
            +QNFV  EE    ++ D+YLYGKEINDETYAICKSDMMIKGN+PENIRVGSTLSTDEF++
Sbjct  241  TQNFV--EEKYPASNRDIYLYGKEINDETYAICKSDMMIKGNNPENIRVGSTLSTDEFSS  298

Query  301  KTFDFMLSNPPYGKSWASEQKYIKDGKEVIDSRFKIKLTDYWGQVEEADATPRSSDGQLL  360
            + FDFMLSNPPYGKSWASEQK IK+GKEV+D+RFK+KL DYWG   E +A PRSSDGQLL
Sbjct  299  NRFDFMLSNPPYGKSWASEQKHIKEGKEVVDGRFKVKLKDYWGVESEQEAIPRSSDGQLL  358

Query  361  FLMEMVNKMKPLSQSPLGSRIASVHNGSSLFTGDAGGGESNIRRYLIENDWLEAIIQLPN  420
            FLMEMV KMK+  +SPLGSRIASVHNGSSLFTGDAG+GESNIRRY+IEND L+AI+QLPN
Sbjct  359  FLMEMVTKMKSPQDSPLGSRIASVHNGSSLFTGDAGSGESNIRRYIIENDMLDAIVQLPN  418

Query  421  NLFYNTGITTYIWLLSNHKAASRQGKVQLIDAGLLYRKLRKNLGNKNCEFAPEHIREIVS  480
            NLFYNTGITTYIWLL+N+K+ +RQGKVQLIDA+LL+RKLRKNLGNKNCEF+PEHI EIVS
Sbjct  419  NLFYNTGITTYIWLLNNNKPENRQGKVQLIDASLLFRKLRKNLGNKNCEFSPEHIAEIVS  478

Query  481  VYEEMQEIERSINPSTQEGEGIAAKVFDNADFGYYKVSIERPKRLKAQFTLERIAELRFD  540
             Y E Q +ER+I+    +  GIAA+VF N DFGYYKV+IERP R +AQF  + I  LRF+
Sbjct  479  TYLENQSVERAIDEKG-DPVGIAAQVFKNQDFGYYKVNIERPDRRNAQFRADLIEPLRFE  537

Query  541  KSLREPMVWAYETYGEAVYTD--LAKHEKDILDWCEKQDLNLNAKQSKALVSPALWHKQl  598
            +S RE M   Y  YGE VY    +   EK+I  WCE +D++LN      L+    W KQ 
Sbjct  538  NSQREVMEYLYAEYGEQVYDAGFVKGIEKEITKWCEENDISLNKAAKTKLLDTKNWMKQR  597

Query  599  ellalaaelMQAIGGSAYTDFNRFKNEVDAVLKTKKTKLSASEKNSILNAVSWYDAEAAK  658
             L+  A++L + IG+  Y DFN+FK+ VDA L +   KLSA+EK++IL+AVSWYD +A K
Sbjct  598  TLVNAASQLHKKIGDEVYNDFNQFKQLVDAELTSLGLKLSAPEKKAILDAVSWYDENAEK  657

Query  659  VEKATLKLTGDKLAQLLAQLGCTEAQLPDYGYYPSDKKGEYLTYETESDLRDTENVPLKE  718
            V K   KL  DKL +LL +  C   +LPD+GYYP+++  E++TYE+ SDLRD+E+VPL +
Sbjct  658  VIKKVAKLKQDKLDDLLENYECELEDLPDFGYYPTGNHNEFVTYESSSDLRDSESVPLEQ  717

Query  719  NSYRYFLREVKPHVPEAWINLDATKIGYEISFNKYFYRHKPLRSIEEVSADILKLESESD  778
            + Y+YFL EVKPHV EAW+NL++ KIGYEISFNKYFYRHKPLRS++EV+ +I+ LE  ++
Sbjct  718  SIYQYFLDEVKPHVDEAWVNLESVKIGYEISFNKYFYRHKPLRSMDEVAKEIIALEQKAE  777

Query  779  GLIREILSLG  788
            GLI +IL+++
Sbjct  778  GLIADILGIS  787

43) CHU_2941 in NC_008255


> EU272902|18|G17|167832524|ACA01834.1|Vibrio_cholerae_Amazonia_3509|-|21794..24175|-|VPI2_0017c|DNA 
methylase HsdM
Length=793

 Score =  903 bits (3422),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 531/788 (68%), Positives = 656/788 (84%), Gaps = 7/788 (0%)

Query  1    MNQAVHNKLVSFIWSIADDCLRDVYVRGKYRDVILPMVVLRRLDALLEPTKDAVLEEMAF  60
            M+++VHNKLVSFIWSIADDCLRDVYVRGKYRDVILPMVVLRRLD+LLEP+K+AVLEE+ F
Sbjct  1    MDHSVHNKLVSFIWSIADDCLRDVYVRGKYRDVILPMVVLRRLDTLLEPSKEAVLEEVRF  60

Query  61   QKDEAKFTEWDENGLRQASGYVFYNTSEWTLQRLHDTATNNQQILQANFEDYLKGYSGNV  120
            QK+E +  E D+  L  +SGYVFYNTS WTLQ L  TATNNQQIL ANFEDYL+G+S NV
Sbjct  61   QKEEMNEIELDDAPLCATSGYVFYNTSKWTLQTLFSTATNNQQILLANFEDYLNGFSENV  120

Query  121  KEIIEKFNLKRQVQHMASKDVLLNVLEKFTSSYINLTPFEKNDPDGRKLPPLSNLGMGYV  180
            KEI+E FNLK Q++HMA+K+VLL+V+EKF S+YINLTP  K+DP+G KLP+LSNLGMGYV
Sbjct  121  KEIVECFNLKAQIRHMAGKNVLLDVVEKFVSPYINLTPAVKEDPEGNKLPALSNLGMGYV  180

Query  181  FEELIRKFNEDNNEEAGEHFTPREVIDLMTHIIFEPIKDKLPPVMTIYDPACGSGGMLTE  240
            FEELIRKFNE+NNEEAGEHFTPREVI+LMTH++F+PIKD+LP  +T+YDPACGSGGMLTE
Sbjct  181  FEELIRKFNEENNEEAGEHFTPREVIELMTHLVFDPIKDNLPLSITVYDPACGSGGMLTE  240

Query  241  SQNFIKDEDGEIKAKGDVYLYGKEINDETYAICKSDMMIKGNNPENIRVGSTLSTNEFAG  300
            +QNF+ +      ++ D+YLYGKEINDETYAICKSDMMIKGNNPENIRVGSTLST+EF++
Sbjct  241  TQNFVEEKYPA--SNRDIYLYGKEINDETYAICKSDMMIKGNNPENIRVGSTLSTDEFSS  298

Query  301  TTFDFMLSNPPYGKSWASEQKFIKDGKDIIDPRFKIKLQNYWGIEEEADATPRSSDGQLL  360
              FDFMLSNPPYGKSWASEQK IK+GK+++D RFK+KL++YWG+E E +A PRSSDGQLL
Sbjct  299  NRFDFMLSNPPYGKSWASEQKHIKEGKEVVDGRFKVKLKDYWGVESEQEAIPRSSDGQLL  358

Query  361  FLMEMVNKMKPLSQSKLGSRIASVHNGSSLFTGDAGGGESNIRRYIIENDWLEAIVQMPN  420
            FLMEMV KMK+  +S LGSRIASVHNGSSLFTGDAG+GESNIRRYIIEND L+AIVQ+PN
Sbjct  359  FLMEMVTKMKSPQDSPLGSRIASVHNGSSLFTGDAGSGESNIRRYIIENDMLDAIVQLPN  418

Query  421  NLFYNTGITTYIWILSNNKSNKRKGKVQLIDAGFMFRKLRKNLGNKNCEFAPEHIREIVS  480
            NLFYNTGITTYIW+L+NNK+++R+GKVQLIDA+++FRKLRKNLGNKNCEF+PEHI EIVS
Sbjct  419  NLFYNTGITTYIWLLNNNKPENRQGKVQLIDASLLFRKLRKNLGNKNCEFSPEHIAEIVS  478

Query  481  VYEKMQAVDRKVDDEQ---GISSKVFDNTDFGYYKVTIERPKRLKAQFTAERIEELRFDK  537
             Y   Q+V+R +D+     GI+++VF N DFGYYKV IERP R +AQF A+ IE LRF++
Sbjct  479  TYLENQSVERAIDEKGDPVGIAAQVFKNQDFGYYKVNIERPDRRNAQFRADLIEPLRFEN  538

Query  538  TLREPMAWAYETYREKVYTE--IAKHEKAIIEWCEKNELNLNAKQTKTLVTQATWQKQLD  595
            + RE M   Y  Y E+VY    +   EK I  WCE N+++LN      L+    W KQ  
Sbjct  539  SQREVMEYLYAEYGEQVYDAGFVKGIEKEITKWCEENDISLNKAAKTKLLDTKNWMKQRT  598

Query  596  LVTLAMDLMKKIGSKEFNDFNLFKERVDEalaakklklsssEKNAILNAVSWYDADAEKV  655
            LV  A +L KKIG   +NDFN FK+ VD  L++  LKLS++EK+AIL+AVSWYD +AEKV
Sbjct  599  LVNAASQLHKKIGDEVYNDFNQFKQLVDAELTSLGLKLSAPEKKAILDAVSWYDENAEKV  658

Query  656  VKGTTKLAGDKLKELLAYLGCKEKELGDYGYFATEKKGEYLEYETESNLRDTENVPLKEA  715
            +K  +KL  DKL +LL    C   +L D+GY++T +  E++ YE+ S+LRD+E+VPL ++
Sbjct  659  IKKVAKLKQDKLDDLLENYECELEDLPDFGYYPTGNHNEFVTYESSSDLRDSESVPLEQS  718

Query  716  IYTYFLREVKPHVGEAWINLDATKIGYEISFNKYFYKHKPLRSIEDVTADILALEKESDG  775
            IY YFL EVKPHV+EAW+NL++ KIGYEISFNKYFY+HKPLRS+++V+ +I+ALE+ ++G
Sbjct  719  IYQYFLDEVKPHVDEAWVNLESVKIGYEISFNKYFYRHKPLRSMDEVAKEIIALEQKAEG  778

Query  776  LIAEILGL  783
            LIA+ILG+
Sbjct  779  LIADILGI  786

44) Slin_6258 in NC_013730


> EU272902|18|G17|167832524|ACA01834.1|Vibrio_cholerae_Amazonia_3509|-|21794..24175|-|VPI2_0017c|DNA 
methylase HsdM
Length=793

 Score =  897 bits (3396),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 537/792 (68%), Positives = 656/792 (83%), Gaps = 14/792 (1%)

Query  1    MNHQSHNKLVSFIWSIADDCLRDVYVRGKYRDVILPMVVLRRLDALLEPGKDEVMEEVRF  60
            M+H  HNKLVSFIWSIADDCLRDVYVRGKYRDVILPMVVLRRLD+LLEP+K+ V+EEVRF
Sbjct  1    MDHSVHNKLVSFIWSIADDCLRDVYVRGKYRDVILPMVVLRRLDTLLEPSKEAVLEEVRF  60

Query  61   QREEAGFTELDVNGLQAASGYVFYNTSVWTLQKLHDTATNNQQLLEANFTDYLDGFSDNV  120
            Q+EE    ELD   L A+SGYVFYNTS WTLQ L  TATNNQQ+L ANF DYL+GFS+NV
Sbjct  61   QKEEMNEIELDDAPLCATSGYVFYNTSKWTLQTLFSTATNNQQILLANFEDYLNGFSENV  120

Query  121  KEIIRKFNLKSQVKHMANKDVLLDVLEKFTSPTINLTPFEKLDPEGRKLPALSNLGMGYV  180
            KEI+  FNLK+Q++HMA K+VLLDV+EKF SP INLTP  K DPEG KLPALSNLGMGYV
Sbjct  121  KEIVECFNLKAQIRHMAGKNVLLDVVEKFVSPYINLTPAVKEDPEGNKLPALSNLGMGYV  180

Query  181  FEELIRKFNEENNEEAGEHFTPREVIDLMTHVIFEPIKDRLPPVMTIYDPACGSGGMLTE  240
            FEELIRKFNEENNEEAGEHFTPREVI+LMTH++F+PIKD LP  +T+YDPACGSGGMLTE
Sbjct  181  FEELIRKFNEENNEEAGEHFTPREVIELMTHLVFDPIKDNLPLSITVYDPACGSGGMLTE  240

Query  241  SQNFIKDEDGLIRAKGDVYLFGKEINDETYAICKSDMMIKGNDPENIKNGSTLSTDEFAG  300
            +QNF+  E+    ++ D+YL+GKEINDETYAICKSDMMIKGN+PENI+ GSTLSTDEF++
Sbjct  241  TQNFV--EEKYPASNRDIYLYGKEINDETYAICKSDMMIKGNNPENIRVGSTLSTDEFSS  298

Query  301  KQFDFMLSNPPYGKSWASEQRHIKDGNEVIDSRFRIKLKNYWGVEEDADAIPRSSDGQLL  360
            ++FDFMLSNPPYGKSWASEQ+HIK+G+EV+D+RF++KLK+YWGVE + +AIPRSSDGQLL
Sbjct  299  NRFDFMLSNPPYGKSWASEQKHIKEGKEVVDGRFKVKLKDYWGVESEQEAIPRSSDGQLL  358

Query  361  FLMEMVSKIKPLAASPSGSRIASVHNGSSLFTGDAGGGESNIRRYLIENDLLDAIIQLPN  420
            FLMEMV+K+K+   SP GSRIASVHNGSSLFTGDAG+GESNIRRY+IEND+LDAI+QLPN
Sbjct  359  FLMEMVTKMKSPQDSPLGSRIASVHNGSSLFTGDAGSGESNIRRYIIENDMLDAIVQLPN  418

Query  421  NLFYNTGITTYIWVLTNSKPANRQGKVQLIDAGPLYRKLRKNLGAKNCELAPEHITEIVK  480
            NLFYNTGITTYIW+L N+KP NRQGKVQLIDA+ L+RKLRKNLG KNCE++PEHI+EIV 
Sbjct  419  NLFYNTGITTYIWLLNNNKPENRQGKVQLIDASLLFRKLRKNLGNKNCEFSPEHIAEIVS  478

Query  481  TYQDLAIVDRTGDD-----GLASKVFDNADFGYYKVTIERPKRLKAQFSAERIAELRFDN  535
            TY +   V+R+ D+     G+A++VF N DFGYYKV IERP R +AQF A+ I  LRF+N
Sbjct  479  TYLENQSVERAIDEKGDPVGIAAQVFKNQDFGYYKVNIERPDRRNAQFRADLIEPLRFEN  538

Query  536  KLREPMVWAWETYGERVYTD--LPALEKDIIDWCEKQELNLARKQQEALLKPDNWLKQQG  593
              RE M      YGE+VY    + ++EK+I  WCE ++++L +  +  LL   NW+KQ+ 
Sbjct  539  SQREVMEYLYAEYGEQVYDAGFVKGIEKEITKWCEENDISLNKAAKTKLLDTKNWMKQRT  598

Query  594  LMNTATKLMKAIGTDEYSNFNIFAREVEMELKALGLKLSASEKKQIMDAVSWYDAEAEKV  653
            L+N+A++L K IG + Y++FN F + V+ EL +LGLKLSA+EKK I+DAVSWYD +AEKV
Sbjct  599  LVNAASQLHKKIGDEVYNDFNQFKQLVDAELTSLGLKLSAPEKKAILDAVSWYDENAEKV  658

Query  654  IkgttklkgekltdlleHLNCTEAQLPDFGYFVTGTPDREKPGEYLEYETESDLRDTENV  713
            IK  +KLK +KL DLLE+ +C   +LPDFGY+ TG  +     E++ YE+ SDLRD+E+V
Sbjct  659  IKKVAKLKQDKLDDLLENYECELEDLPDFGYYPTGNHN-----EFVTYESSSDLRDSESV  713

Query  714  PLKEDIHDYFLREVKPHVSEAWINLDATKIGYEISFNKYFYRHKPLRDIAAVSADILQLE  773
            PL + I +YFL EVKPHV EAW+NL++ KIGYEISFNKYFYRHKPLR +  V+ +I+ LE
Sbjct  714  PLEQSIYQYFLDEVKPHVDEAWVNLESVKIGYEISFNKYFYRHKPLRSMDEVAKEIIALE  773

Query  774  DESEGLIKAILA  785
            + +EGLI  IL+
Sbjct  774  QKAEGLIADILG  785

45) FBFL15_1800 in NC_016001


> EU272902|18|G17|167832524|ACA01834.1|Vibrio_cholerae_Amazonia_3509|-|21794..24175|-|VPI2_0017c|DNA 
methylase HsdM
Length=793

 Score =  886 bits (3354),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 529/789 (68%), Positives = 655/789 (84%), Gaps = 10/789 (1%)

Query  1    MNQSVHNKLVSFIWSIADDCLRDVYVRGKYRDVILPMVVLRRLDALLEPTKDAVMEELAF  60
            M++SVHNKLVSFIWSIADDCLRDVYVRGKYRDVILPMVVLRRLD+LLEP+K+AV+EE+ F
Sbjct  1    MDHSVHNKLVSFIWSIADDCLRDVYVRGKYRDVILPMVVLRRLDTLLEPSKEAVLEEVRF  60

Query  61   QRDEAGLTEWEENGMCAASGYVFYNTSEWTLQRLHDTATNSQQLLQANFEDYLNGFSTNV  120
            Q++E    E ++  +CA+SGYVFYNTS WTLQ L  TATN+QQ+L ANFEDYLNGFS NV
Sbjct  61   QKEEMNEIELDDAPLCATSGYVFYNTSKWTLQTLFSTATNNQQILLANFEDYLNGFSENV  120

Query  121  KEIIEKFKLRSQIKHMAAKDVLLDVLEKFTSPDINLTPFDKNDSNGRKLHALSNLGMGYV  180
            KEI+E F+L++QI+HMA+K+VLLDV+EKF SP INLTP  K+D++G KL ALSNLGMGYV
Sbjct  121  KEIVECFNLKAQIRHMAGKNVLLDVVEKFVSPYINLTPAVKEDPEGNKLPALSNLGMGYV  180

Query  181  FEELIRKFNEDNNEEAGEHFTPREVIDLMTHIIFDPIKNNLPPVMTIYDPACGSGGMLTE  240
            FEELIRKFNE+NNEEAGEHFTPREVI+LMTH++FDPIK+NLP  +T+YDPACGSGGMLTE
Sbjct  181  FEELIRKFNEENNEEAGEHFTPREVIELMTHLVFDPIKDNLPLSITVYDPACGSGGMLTE  240

Query  241  AQNFIKDEEGEIRAINSDVYLYGKEINDETYAICKSDMMIKGNNPENIRVGSTLSTDEFA  300
            +QNF+   E    A N D+YLYGKEINDETYAICKSDMMIKGNNPENIRVGSTLSTDEF+
Sbjct  241  TQNFV---EEKYPASNRDIYLYGKEINDETYAICKSDMMIKGNNPENIRVGSTLSTDEFS  297

Query  301  GTTFDFMLSNPPYGKSWASEQKYIKDGKDVIDTRFQIQLKNYWGVADDADAIPRSSDGQL  360
            +  FDFMLSNPPYGKSWASEQK IK+GK+V+D RF+++LK+YWGV  + +AIPRSSDGQL
Sbjct  298  SNRFDFMLSNPPYGKSWASEQKHIKEGKEVVDGRFKVKLKDYWGVESEQEAIPRSSDGQL  357

Query  361  LFLMEMVSKMKPLSQSPTGTRIASVHNGSSLFTGDAGGGESNIRRYIIENDWLEAIVQMP  420
            LFLMEMV+KMK+  +SP G+RIASVHNGSSLFTGDAG+GESNIRRYIIEND L+AIVQ+P
Sbjct  358  LFLMEMVTKMKSPQDSPLGSRIASVHNGSSLFTGDAGSGESNIRRYIIENDMLDAIVQLP  417

Query  421  NNLFYNTGITTYIWILSNNKTANRKGKVQLIDAGQLYRKLRKNLGNKNCEFAPEHITEIV  480
            NNLFYNTGITTYIW+L+NNK  NR+GKVQLIDA+ L+RKLRKNLGNKNCEF+PEHI+EIV
Sbjct  418  NNLFYNTGITTYIWLLNNNKPENRQGKVQLIDASLLFRKLRKNLGNKNCEFSPEHIAEIV  477

Query  481  KTYTDLKAIERTTDD-----SIASKVFDNSDFGYHKVTIERPKRLNAQFTEERIAELRFD  535
             TY + +++ER+ D+     +IA++VF N DFGY KV IERP R NAQF  + I  LRF+
Sbjct  478  STYLENQSVERAIDEKGDPVGIAAQVFKNQDFGYYKVNIERPDRRNAQFRADLIEPLRFE  537

Query  536  KTLKEAMVYAYKMYGEKVYTE--IAKHEKELTDWAEKQELNLNTKQLKALCSETLWNKQL  593
            ++ +E M Y Y  YGE+VY    +   EKE+T W E ++++LN      L     W KQ 
Sbjct  538  NSQREVMEYLYAEYGEQVYDAGFVKGIEKEITKWCEENDISLNKAAKTKLLDTKNWMKQR  597

Query  594  FLLENAQVLLKEIGTDLSTDFNTFkdkvdevvkakklklsasekNAILNAISWYDADAEK  653
             L++ A  L K IG ++  DFN FK+ VD  + +  LKLSA+EK+AIL+A+SWYD +AEK
Sbjct  598  TLVNAASQLHKKIGDEVYNDFNQFKQLVDAELTSLGLKLSAPEKKAILDAVSWYDENAEK  657

Query  654  VVKSTVKLTGDKLEKLLIHLGCTENELADYGYFPTDKKGEYITYETESDLRDTENIPLKE  713
            V+K   KL  DKL+ LL +  C  ++L+D+GY+PT++  E++TYE+ SDLRD+E++PL +
Sbjct  658  VIKKVAKLKQDKLDDLLENYECELEDLPDFGYYPTGNHNEFVTYESSSDLRDSESVPLEQ  717

Query  714  DIYIYFLREVKPHVAEAWINLDATKIGYEISFNKYFYQHKPLRSIEEVTADILALEKESD  773
             IY YFL EVKPHV EAW+NL++ KIGYEISFNKYFY+HKPLRS++EV+ +I+ALE+ ++
Sbjct  718  SIYQYFLDEVKPHVDEAWVNLESVKIGYEISFNKYFYRHKPLRSMDEVAKEIIALEQKAE  777

Query  774  GLIAEILAL  782
            GLIA+IL++
Sbjct  778  GLIADILGI  786

46) ZPR_4122 in NC_014041


> EU272902|18|G17|167832524|ACA01834.1|Vibrio_cholerae_Amazonia_3509|-|21794..24175|-|VPI2_0017c|DNA 
methylase HsdM
Length=793

 Score =  884 bits (3347),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 514/787 (66%), Positives = 642/787 (82%), Gaps = 9/787 (1%)

Query  1    MTQNSHSKLIAFIWSIADDCLRDVYVRGKYRDVILPMVVLRRLDALLEPSKKEVMDEVQF  60
            M ++ H+KL++FIWSIADDCLRDVYVRGKYRDVILPMVVLRRLD+LLEPSK  V++EV+F
Sbjct  1    MDHSVHNKLVSFIWSIADDCLRDVYVRGKYRDVILPMVVLRRLDTLLEPSKEAVLEEVRF  60

Query  61   QTVEAGFTELESEGLKTAAGYEFYNTSKWTLQLLKDTASNNQSILLANFEDYILGFSDNV  120
            Q  E    EL+   L +++GY FYNTSKWTLQ L  TA+NNQ ILLANFEDY+ GFS+NV
Sbjct  61   QKEEMNEIELDDAPLCATSGYVFYNTSKWTLQTLFSTATNNQQILLANFEDYLNGFSENV  120

Query  121  KEIISKFNLVRQIKHMATKDVLLDVLEKFTSPRINLTPFEKEDPDGYKLPALSNLGMGYV  180
            KEI+  FNL  QI+HMA K+VLLDV+EKF SP INLTP  KEDP+G KLPALSNLGMGYV
Sbjct  121  KEIVECFNLKAQIRHMAGKNVLLDVVEKFVSPYINLTPAVKEDPEGNKLPALSNLGMGYV  180

Query  181  FEELIRKFNEENNEEAGEHFTPREVIELMTHLVFEPVKHQLPPVMTIYDPACGSGGMLTE  240
            FEELIRKFNEENNEEAGEHFTPREVIELMTHLVF+P+K++LP  +T+YDPACGSGGMLTE
Sbjct  181  FEELIRKFNEENNEEAGEHFTPREVIELMTHLVFDPIKDNLPLSITVYDPACGSGGMLTE  240

Query  241  SQNFIKDEAGAIQAKGDVYLFGKEINDETYAICKSDMMIKGNDPQNIRLGSTLSTDEFSR  300
            +QNF+ +   A  ++ D+YL+GKEINDETYAICKSDMMIKGN+P+NIR+GSTLSTDEFS 
Sbjct  241  TQNFVEEKYPA--SNRDIYLYGKEINDETYAICKSDMMIKGNNPENIRVGSTLSTDEFSS  298

Query  301  KNFDFMLSNPPYGKSWASEQKYIKDGKDIIDPRFTIQLSNYWQETDTEKAIPRSSDGQLL  360
            + FDFMLSNPPYGKSWASEQK IK+GK+++D RF ++L +YW     + AIPRSSDGQLL
Sbjct  299  NRFDFMLSNPPYGKSWASEQKHIKEGKEVVDGRFKVKLKDYWGVESEQEAIPRSSDGQLL  358

Query  361  FLMEMVSKMKNLKQSPLGSRIASVHNGSSLFTGDAGSGESNIRRYLIENDLLEAIVQLPN  420
            FLMEMV+KMK+ ++SPLGSRIASVHNGSSLFTGDAGSGESNIRRY+IEND+L+AIVQLPN
Sbjct  359  FLMEMVTKMKSPQDSPLGSRIASVHNGSSLFTGDAGSGESNIRRYIIENDMLDAIVQLPN  418

Query  421  NLFYNTGITTYIWLLSNNKTKERQGKVQLIDAQPLYQKLRKNLGQKNCEFTPEHITEITQ  480
            NLFYNTGITTYIWLL+NNK  +RQGKVQLIDA  L++KLRKNLG+KNCEF+PEHI+EI  
Sbjct  419  NLFYNTGITTYIWLLNNNKPENRQGKVQLIDASLLFRKLRKNLGNKNCEFSPEHIAEIVS  478

Query  481  TFLNSEAREREEDDQ-----LASKIFNNTDFGYYKVTIERPKRLRSQFTLEAIESLRYYS  535
            T+L++++ ER  D++     +A+++F+N DFGYYKV IERP R  +QF  + IE+LR+ +
Sbjct  479  TYLENQSVERAIDEKGDPVGIAAQVFKNQDFGYYKVNIERPDRRNAQFRADLIEPLRFEN  538

Query  536  QLQEPMEYAYKTFGKKVYTE--LPSIKTEILNWCEANDISLSSKKKAQLTAKKTWEDAKF  593
              +E MEY Y  +G +VY    + +I  EI +WCE NDISL+   K++L   K W   + 
Sbjct  539  SQREVMEYLYAEYGEQVYDAGFVKGIEKEITKWCEENDISLNKAAKTKLLDTKNWMKQRT  598

Query  594  LVDTATKLYEAIGDAVFMDFNHFSKQVNKALKKLEIKLSNAQKKAILDAVSVYDPEAEKV  653
            LV++A++L   IGD V+ DFN+F + V+  L  L +KLS ++KKAILDAVS YD +AEKV
Sbjct  599  LVNAASQLHKKIGDEVYNDFNQFKQLVDAELTSLGLKLSAPEKKAILDAVSWYDENAEKV  658

Query  654  IKTTKILKGEKLENLCAHLDCTPDQLSHFGYFPSGNKGTYTIYESESDLRDYENVPLDET  713
            IK    LK +KL++L  + +C  ++L++FGY+P+GN   +  YES SDLRD E+VPL+++
Sbjct  659  IKKVAKLKQDKLDDLLENYECELEDLPDFGYYPTGNHNEFVTYESSSDLRDSESVPLEQS  718

Query  714  VYDYFLREVSTHVEEAWIDLDKTKIGYEISFNKYFYQHKALRPLDEIDKDIRELETKSEG  773
            +Y+YFL EV  HV+EAW++L+  KIGYEISFNKYFY+HK+LR++DE+ K+I  LE K+EG
Sbjct  719  IYQYFLDEVKPHVDEAWVNLESVKIGYEISFNKYFYRHKPLRSMDEVAKEIIALEQKAEG  778

Query  774  LIMDILN  780
            LI DIL 
Sbjct  779  LIADILG  785

47) WQG_21370 in NC_020515


> EU272902|18|G17|167832524|ACA01834.1|Vibrio_cholerae_Amazonia_3509|-|21794..24175|-|VPI2_0017c|DNA 
methylase HsdM
Length=793

 Score =  853 bits (3231),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 504/787 (65%), Positives = 638/787 (82%), Gaps = 13/787 (1%)

Query  5    MNHSAHNRLVSFIWSIADDCLRDVYVRGKYRDVILPMTVLRRLDSLLEPTKQAVLEEITF  64
            M+HS HN+LVSFIWSIADDCLRDVYVRGKYRDVILPM VLRRLD+LLEP+K+AVLEE+ F
Sbjct  1    MDHSVHNKLVSFIWSIADDCLRDVYVRGKYRDVILPMVVLRRLDTLLEPSKEAVLEEVRF  60

Query  65   WGDEVAP----EEELQKASGYVFYNTSKWTLLQLKDNANNNAQYLLHNFDEYLNGFSPNV  120
              +E+      +  L  +SGYVFYNTSKWTL  L   A NN Q LL NF++YLNGFS NV
Sbjct  61   QKEEMNEIELDDAPLCATSGYVFYNTSKWTLQTLFSTATNNQQILLANFEDYLNGFSENV  120

Query  121  QEIINRFNLRSQIAHMSNKGVLLAVLEKFVSPYINLTPFEKQDPEGNKLPALTNLGMGYV  180
            +EI++ FNL++QI HM+ K VLL V+EKFVSPYINLTP  K+DPEGNKLPAL+NLGMGYV
Sbjct  121  KEIVECFNLKAQIRHMAGKNVLLDVVEKFVSPYINLTPAVKEDPEGNKLPALSNLGMGYV  180

Query  181  FEELIRKFNEENNEEAGEHFTPREVIELMTHLVFDPIASQIPPVISVYDPACGSGGMLTE  240
            FEELIRKFNEENNEEAGEHFTPREVIELMTHLVFDPI  ++P  I+VYDPACGSGGMLTE
Sbjct  181  FEELIRKFNEENNEEAGEHFTPREVIELMTHLVFDPIKDNLPLSITVYDPACGSGGMLTE  240

Query  241  SQNFIEEKYPLANTDRTIYLYGKEINDETYAICKSDMMIKGNNPEHIKVGSTLASDEFGG  300
            +QNF+EEKYP   ++R IYLYGKEINDETYAICKSDMMIKGNNPE+I+VGSTL++DEF++
Sbjct  241  TQNFVEEKYP--ASNRDIYLYGKEINDETYAICKSDMMIKGNNPENIRVGSTLSTDEFSS  298

Query  301  QYFDFMLSNPPYGKSWSSDESYIKDGKTVIDSRFKVELADYWGNLAEYDATPRTSDGQLL  360
            + FDFMLSNPPYGKSW+S++  IK+GK V+D+RFKV L DYWG  +E +A PR+SDGQLL
Sbjct  299  NRFDFMLSNPPYGKSWASEQKHIKEGKEVVDGRFKVKLKDYWGVESEQEAIPRSSDGQLL  358

Query  361  FLMEMANKMKPVAMNGIGSRVASVHNGSSLFTGDAGGGESNIRRYLIENDLLEAIIQLPN  420
            FLMEM  KMK+   + +GSR+ASVHNGSSLFTGDAG+GESNIRRY+IEND+L+AI+QLPN
Sbjct  359  FLMEMVTKMKSPQDSPLGSRIASVHNGSSLFTGDAGSGESNIRRYIIENDMLDAIVQLPN  418

Query  421  NLFYNTGITTYIWLLNNNKPKQRKGKVQLIDANELYSKLRKNLGEKNCELTAEHIQRIMQ  480
            NLFYNTGITTYIWLLNNNKP +R+GKVQLIDA+ L+ KLRKNLG+KNCE+++EHI  I+ 
Sbjct  419  NLFYNTGITTYIWLLNNNKPENRQGKVQLIDASLLFRKLRKNLGNKNCEFSPEHIAEIVS  478

Query  481  SYLACENLNRT-------DGLAAKVFDNRDFGYYKVAINRPDRRKVQFTQAAIAPLRFDK  533
            +YL  ++++R+        G+AA+VF N+DFGYYKV I+RPDRR+ QF    I PLRF++
Sbjct  479  TYLENQSVERAIDEKGDPVGIAAQVFKNQDFGYYKVNIERPDRRNAQFRADLIEPLRFEN  538

Query  534  SLIEPMQFLFERHGQAVYFAENLANFVEELTAWAEQNGYAlntknknkvlntETWSKANI  593
            S  E M++L+   G+ VY A  +  +  E+T W E+N+ +LN   K K+L+T  W K   
Sbjct  539  SQREVMEYLYAEYGEQVYDAGFVKGIEKEITKWCEENDISLNKAAKTKLLDTKNWMKQRT  598

Query  594  RFKAAEKLHSHFGEQIFMDFNAFVKQADNVLKAEKIKLSSADKKAIYQAVSSYDETAEKV  653
              +AA +LH  +G++++ DFN F +  D  L +  +KLS+++KKAI +AVS YDE AEKV
Sbjct  599  LVNAASQLHKKIGDEVYNDFNQFKQLVDAELTSLGLKLSAPEKKAILDAVSWYDENAEKV  658

Query  654  VSKIHTFTENELAKLLGKLKTDEKHLPDFGYYPTGKQGEFVYYETNSELSDSENIPLNQD  713
            + K+  + ++ L  LL +   +  +LPDFGYYPTG++ EFV YE++S+L DSE++PL+Q 
Sbjct  659  IKKVAKLKQDKLDDLLENYECELEDLPDFGYYPTGNHNEFVTYESSSDLRDSESVPLEQS  718

Query  714  IHSYFVAEVKPHIDETWIDINSIKIGYEISFNKYFYQHKALRLLSEIKADILALEQQAEG  773
            I  YF+ EVKPH+DE+W++++S+KIGYEISFNKYFY+HK+LR + E+  +I+ALEQ+AEG
Sbjct  719  IYQYFLDEVKPHVDEAWVNLESVKIGYEISFNKYFYRHKPLRSMDEVAKEIIALEQKAEG  778

Query  774  LIGEILG  780
            LI++ILG
Sbjct  779  LIADILG  785

48) Fleli_0172 in NC_018018


> EU272902|18|G17|167832524|ACA01834.1|Vibrio_cholerae_Amazonia_3509|-|21794..24175|-|VPI2_0017c|DNA 
methylase HsdM
Length=793

 Score =  833 bits (3155),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 514/790 (66%), Positives = 649/790 (83%), Gaps = 9/790 (1%)

Query  1    MDTATHNKLVAFIWSIADDCLRDVYVRGKYRDVILPMVVLRRLDVLLEPTKDAVLEEVRF  60
            MD + HNKLV+FIWSIADDCLRDVYVRGKYRDVILPMVVLRRLD LLEP+K+AVLEEVRF
Sbjct  1    MDHSVHNKLVSFIWSIADDCLRDVYVRGKYRDVILPMVVLRRLDTLLEPSKEAVLEEVRF  60

Query  61   QTKELEFTELDPAGLKDASKYVFYNTSKWTLQSLKETTTNSKQIIQANFEEYLNGFSENV  120
            Q  E++  ELD A L  +S YVFYNTSKWTLQ+L  T+TN++QI+ ANFE+YLNGFSENV
Sbjct  61   QKEEMNEIELDDAPLCATSGYVFYNTSKWTLQTLFSTATNNQQILLANFEDYLNGFSENV  120

Query  121  KEIIDKFNLKNQVQHMISKDVWLDVLEKFTSKDINLTPFETEDSEGRKQPPLSNLGMGYV  180
            KEI++ FNLK Q++HM +K+V LDV+EKF S  INLTP   ED+EG K P+LSNLGMGYV
Sbjct  121  KEIVECFNLKAQIRHMAGKNVLLDVVEKFVSPYINLTPAVKEDPEGNKLPALSNLGMGYV  180

Query  181  FEELIRKFNEENNEEAGEHFTPREVIDLMTHLVFEPIKDNLPSVMTIYDPACGSGGMLTE  240
            FEELIRKFNEENNEEAGEHFTPREVI+LMTHLVF+PIKDNLP  +T+YDPACGSGGMLTE
Sbjct  181  FEELIRKFNEENNEEAGEHFTPREVIELMTHLVFDPIKDNLPLSITVYDPACGSGGMLTE  240

Query  241  SQNFIQDEEGTIKATGSVYLYGKEINDETYAICKSDMMIRGNSPENIRVGSTLSTDEFAG  300
            +QNF+++   +  +   +YLYGKEINDETYAICKSDMMI+GN+PENIRVGSTLSTDEF++
Sbjct  241  TQNFVEEKYPA--SNRDIYLYGKEINDETYAICKSDMMIKGNNPENIRVGSTLSTDEFSS  298

Query  301  TQFNYMLSNPPYGKSWASEQKYIKDGKEVIDSRFIVQLNNYWGESETVEAVPRSSDGQLL  360
             +F++MLSNPPYGKSWASEQK IK+GKEV+D+RF V+L++YWG     EA+PRSSDGQLL
Sbjct  299  NRFDFMLSNPPYGKSWASEQKHIKEGKEVVDGRFKVKLKDYWGVESEQEAIPRSSDGQLL  358

Query  361  FLMEMVSKMKPNNEQTNGSRIASVHNGSSLFTGDAGGGESNIRRYIIENDMLEAIIQLPN  420
            FLMEMV+KMK+ ++   GSRIASVHNGSSLFTGDAG+GESNIRRYIIENDML+AI+QLPN
Sbjct  359  FLMEMVTKMKSPQDSPLGSRIASVHNGSSLFTGDAGSGESNIRRYIIENDMLDAIVQLPN  418

Query  421  NLFYNTGITTYIWLLSNAKPQNRKGKVQLIDASQQFTKLRKNLGAKNCELTAEHINEILN  480
            NLFYNTGITTYIWLL+N KP+NR+GKVQLIDAS  F KLRKNLG KNCE+++EHI EI++
Sbjct  419  NLFYNTGITTYIWLLNNNKPENRQGKVQLIDASLLFRKLRKNLGNKNCEFSPEHIAEIVS  478

Query  481  VHLNFETTEPSQDKP------TSKVFDNKDFGFYKATIERPKRLKAQFSEEKINLLRFDK  534
              L+ ++ E + D        +++VF N+DFG+YK  IERP R +AQF  + I+ LRF++
Sbjct  479  TYLENQSVERAIDEKGDPVGIAAQVFKNQDFGYYKVNIERPDRRNAQFRADLIEPLRFEN  538

Query  535  TLLEPMQWAYQEYGEEIYTQLkedktikekiikwteeNGIDLNSKKRNLLTSPKTWNKYK  594
            +  E M+  Y EYGE++Y      K I   I KW EEN+I LN   +  L   K W K +
Sbjct  539  SQREVMEYLYAEYGEQVYDA-GFVKGIEKEITKWCEENDISLNKAAKTKLLDTKNWMKQR  597

Query  595  TILEAAQKLMQLIGIEEYNDFNVFQKEVEKQIKEHKMTLSSSEKNAIYNAITWYDQTAEK  654
            T+++AA +L + IG E YNDFN F++ V+ ++    + LS++EK+AI +A++WYD+ AEK
Sbjct  598  TLVNAASQLHKKIGDEVYNDFNQFKQLVDAELTSLGLKLSAPEKKAILDAVSWYDENAEK  657

Query  655  VIKKTQklndekldellekldCTEQQLSDYGYYATSKKGEYIIYETESDLRDFENIPLKD  714
            VIKK  KL+++KLD+LLE+ +C  ++L+D+GYY+T++  E++ YE+ SDLRD E++PL +
Sbjct  658  VIKKVAKLKQDKLDDLLENYECELEDLPDFGYYPTGNHNEFVTYESSSDLRDSESVPLEQ  717

Query  715  NIYVYFLEEVKPHVEEAWIDLEKTKIGYEISFNKYFYQHKPLRNIEEVSKEILQLEKQNE  774
            +IY YFL+EVKPHV+EAW++LE  KIGYEISFNKYFY+HKPLR+++EV+KEI+ LE++ E
Sbjct  718  SIYQYFLDEVKPHVDEAWVNLESVKIGYEISFNKYFYRHKPLRSMDEVAKEIIALEQKAE  777

Query  775  GLILEILNLS  784
            GLI +IL +S
Sbjct  778  GLIADILGIS  787

49) hsdM in NC_016940


> EU272902|18|G17|167832524|ACA01834.1|Vibrio_cholerae_Amazonia_3509|-|21794..24175|-|VPI2_0017c|DNA 
methylase HsdM
Length=793

 Score =  830 bits (3143),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 522/787 (67%), Positives = 638/787 (82%), Gaps = 13/787 (1%)

Query  1    MNTAVHNKLVSFIWSIADDCLRDIYVRGKYRDVILPMVVLRRLDALLEDTKEAVLEEAYF  60
            M+ +VHNKLVSFIWSIADDCLRD+YVRGKYRDVILPMVVLRRLD+LLE +KEAVLEE  F
Sbjct  1    MDHSVHNKLVSFIWSIADDCLRDVYVRGKYRDVILPMVVLRRLDTLLEPSKEAVLEEVRF  60

Query  61   QKEVMKLVDWDEHALQHASGYVFYNTSTWTLQRFYERTSNNPQLLLANFEEYLLGFSQNV  120
            QKE M+ ++ D+ +L  +SGYVFYNTS WTLQ ++  ++NN Q+LLANFE+YL GFS+NV
Sbjct  61   QKEEMNEIELDDAPLCATSGYVFYNTSKWTLQTLFSTATNNQQILLANFEDYLNGFSENV  120

Query  121  QEIIEKFNLRAQIRHMVNKDVLLAVVEKFISPGINLTNQDKLDPEGNKLPALTNLGMGYV  180
            +EI+E FNL+AQIRHM  K+VLL VVEKF+SP INLT   K DPEGNKLPAL+NLGMGYV
Sbjct  121  KEIVECFNLKAQIRHMAGKNVLLDVVEKFVSPYINLTPAVKEDPEGNKLPALSNLGMGYV  180

Query  181  FEELIRKFNEENNEEAGEHFTPREVIDLMSRLVFLPIKEALPKVMTIYDPACGSGGMLTE  240
            FEELIRKFNEENNEEAGEHFTPREVI+LM++LVF PIK+ LP  +T+YDPACGSGGMLTE
Sbjct  181  FEELIRKFNEENNEEAGEHFTPREVIELMTHLVFDPIKDNLPLSITVYDPACGSGGMLTE  240

Query  241  AQNFVKDEEGEIRCTDHDVYLFGKEINDETYAICKSDMMIKGNDPANIRSGSTLSTDEFA  300
            +QNFV   E     +++D+YL+GKEINDETYAICKSDMMIKGN+P NIR GSTLSTDEF+
Sbjct  241  TQNFV---EEKYPASNRDIYLYGKEINDETYAICKSDMMIKGNNPENIRVGSTLSTDEFS  297

Query  301  GLQFDFMLSNPPYGKSWSSEKKYI-DGVDGTDVRFLVPLKDYWGKEEIVAATPRSSDGQL  359
            + +FDFMLSNPPYGKSW+SE+K I +G +  D RF V LKDYWG E    A PRSSDGQL
Sbjct  298  SNRFDFMLSNPPYGKSWASEQKHIKEGKEVVDGRFKVKLKDYWGVESEQEAIPRSSDGQL  357

Query  360  LFLMEMLSKMKT--ESPTGSRIASVHNGSSLFTGDAGSGESNIRRYLIEQDYLEAIIQLP  417
            LFLMEM++KMK+  +SP GSRIASVHNGSSLFTGDAGSGESNIRRY+IE+D L+AI+QLP
Sbjct  358  LFLMEMVTKMKSPQDSPLGSRIASVHNGSSLFTGDAGSGESNIRRYIIENDMLDAIVQLP  417

Query  418  NNLFYNTGITTYIWLLSNRKSAERAGKVQLIDASQLYQKLRKNLGDKNCELSQAHIGEIL  477
            NNLFYNTGITTYIWLL+N K+ +R GKVQLIDAS L++KLRKNLG+KNCE+S  HI+EI+
Sbjct  418  NNLFYNTGITTYIWLLNNNKPENRQGKVQLIDASLLFRKLRKNLGNKNCEFSPEHIAEIV  477

Query  478  SVYQELATVERQGEE-----GIAAQVFENQDFGYYKVNIERPQRLRAKFSAEAIESLLYQ  532
            S Y E  +VER  +E     GIAAQVF NQDFGYYKVNIERP+R  A+F A+ IE+L ++
Sbjct  478  STYLENQSVERAIDEKGDPVGIAAQVFKNQDFGYYKVNIERPDRRNAQFRADLIEPLRFE  537

Query  533  RGLEAPMRWAYAEFGEDVYQQ--LGQHKKALLAYCEAEGISLSAKQKTALTTAKGWEKGq  590
             +    M   YAE+GE+VY+   +    K +   CE ++ISL+   KT L  +K W K +
Sbjct  538  NSQREVMEYLYAEYGEQVYDAGFVKGIEKEITKWCEENDISLNKAAKTKLLDTKNWMKQR  597

Query  591  alyaaaqqlmqaIGEQVYFDFNQFVAALAKQIKALGLKLSATEKKAIYSAVSTYDAKAEK  650
            +L  AA QL + IG++VY DFNQF   +  ++ +LGLKLSA EKKAI  AVS YD +AEK
Sbjct  598  TLVNAASQLHKKIGDEVYNDFNQFKQLVDAELTSLGLKLSAPEKKAILDAVSWYDENAEK  657

Query  651  VIKRRLKLSGQKLTNLLAHLGCTLEQLPDFGYYPSGKAGeyleyesesslRDSENIPLKE  710
            VIK+  KL  +KL +LL +  C LE+LPDFGYYP+G+  E++ YES S LRDSE++PL +
Sbjct  658  VIKKVAKLKQDKLDDLLENYECELEDLPDFGYYPTGNHNEFVTYESSSDLRDSESVPLEQ  717

Query  711  EIHSYFLEEVRPHIAEAWINLDSVKLGYEISFNKYFYRHQPLRSLEEVSQEIRTLEAESD  770
             I  YFL+EV+PH+ EAW+NL+SVK+GYEISFNKYFYRH+PLRS++EV++EI +LE  ++
Sbjct  718  SIYQYFLDEVKPHVDEAWVNLESVKIGYEISFNKYFYRHKPLRSMDEVAKEIIALEQKAE  777

Query  771  GLIAEIL  777
            GLIA+IL
Sbjct  778  GLIADIL  784

50) hsdM in NC_020156


> EU272902|18|G17|167832524|ACA01834.1|Vibrio_cholerae_Amazonia_3509|-|21794..24175|-|VPI2_0017c|DNA 
methylase HsdM
Length=793

 Score =  820 bits (3105),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 492/775 (64%), Positives = 612/775 (79%), Gaps = 32/775 (4%)

Query  1    MIVLRRLDALLEPTKDAVLEELAFQRDEAGFTEWDEVGLREASGYVFYNTSTYTLQKLKD  60
            M+VLRRLD+LLEP+K+AVLEE+ FQ++E    E D+  L  +SGYVFYNTS  TLQ L  
Sbjct  37   MVVLRRLDTLLEPSKEAVLEEVRFQKEEMNEIELDDAPLCATSGYVFYNTSKWTLQTLFS  96

Query  61   TATNSQQILQANFEDYLNGFSPNVKEIIEKFKLRSQVRHMATKDVLLDVLEKFTSPYINV  120
            TATN+QQIL ANFEDYLNGFS NVKEI+E F+L++Q+RHMA K+VLLDV+EKF SPYIN+
Sbjct  97   TATNNQQILLANFEDYLNGFSENVKEIVECFNLKAQIRHMAGKNVLLDVVEKFVSPYINL  156

Query  121  TPFEKEDPEGRKLPALSNLGMGYVFEELIRKFNEENNEEAGEHFTPREVIDLMTHIIFDP  180
            TP  KEDPEG KLPALSNLGMGYVFEELIRKFNEENNEEAGEHFTPREVI+LMTH++FDP
Sbjct  157  TPAVKEDPEGNKLPALSNLGMGYVFEELIRKFNEENNEEAGEHFTPREVIELMTHLVFDP  216

Query  181  IKDNLPEVMTIYDPACGSGGMLTESQNFIKDEEGAIRATGDVYLFGKEINDETYAICKSD  240
            IKDNLP  +T+YDPACGSGGMLTE+QNF+ +   A  +  D+YL+GKEINDETYAICKSD
Sbjct  217  IKDNLPLSITVYDPACGSGGMLTETQNFVEEKYPA--SNRDIYLYGKEINDETYAICKSD  274

Query  241  MMIKGNDPENIKVGSTLSTDEFAGKTFDFMLSNPPYGKSWSSEQKYIKDGKDIIDPRFKI  300
            MMIKGN+PENI+VGSTLSTDEF+++ FDFMLSNPPYGKSW+SEQK IK+GK+++D RFK+
Sbjct  275  MMIKGNNPENIRVGSTLSTDEFSSNRFDFMLSNPPYGKSWASEQKHIKEGKEVVDGRFKV  334

Query  301  SLKNYWNVEEEVDAIPRSSDGQLLFLMEMVDKMKSLSQSPAGTRIASVHNGSGLFTGDAG  360
             LK+YW VE E +AIPRSSDGQLLFLMEMV KMKS  +SP G+RIASVHNGS+LFTGDAG
Sbjct  335  KLKDYWGVESEQEAIPRSSDGQLLFLMEMVTKMKSPQDSPLGSRIASVHNGSSLFTGDAG  394

Query  361  GGESNIRRYIIENDWLEAIVQLPNNLFYNTGITTYIWILSNNKATDRKGKVQLIDAGQLY  420
            +GESNIRRYIIEND L+AIVQLPNNLFYNTGITTYIW+L+NNK+ +R+GKVQLIDA+ L+
Sbjct  395  SGESNIRRYIIENDMLDAIVQLPNNLFYNTGITTYIWLLNNNKPENRQGKVQLIDASLLF  454

Query  421  RKLRKNLGNKNCEFAPEHVKEITSVYMSSLSRKRTENQ-----PLASQIFDNEDFGYYKA  475
            RKLRKNLGNKNCEF+PEH+ EI S Y+ + S  R+ ++      +A+Q+F N+DFGYYK 
Sbjct  455  RKLRKNLGNKNCEFSPEHIAEIVSTYLENQSVERAIDEKGDPVGIAAQVFKNQDFGYYKV  514

Query  476  TIERPKRLKAQFTPERIESLRYDRVLQEPMQYAFETYGERIYTN--TKQHAAELLEWCEK  533
             IERP R +AQF ++ IE+LR++   +E M+Y +  YGE++Y     K    E+  WCE 
Sbjct  515  NIERPDRRNAQFRADLIEPLRFENSQREVMEYLYAEYGEQVYDAGFVKGIEKEITKWCEE  574

Query  534  NELNLSAANKTKLTKPATWQKHLNQLKCALALSNVIGDKEYRDFNIFKKDVDDEVKAQKL  593
            N+++L+ A KTKL     W K+   ++ A  L + IGD  Y DFN FK+ VD E+ +  L
Sbjct  575  NDISLNKAAKTKLLDTKNWMKQRTLVNAASQLHKKIGDEVYNDFNQFKQLVDAELTSLGL  634

Query  594  SISASDKKAILNAVSWYDATAEKVIKKVEKLSGDKLKKLLAHLDCKEEDLADFGYYAHDH  653
             +SA++KKAIL+AVSWYD  AEKVIKKV KL  DKL  LL + +C  EDL+DFGYY+   
Sbjct  635  KLSAPEKKAILDAVSWYDENAEKVIKKVAKLKQDKLDDLLENYECELEDLPDFGYYP---  691

Query  654  PDVTLSLSKRFSNSKALGIITPKKGEYITYETESDLRDTENVPLKDNIHHYFKKEVQPHV  713
                                T +  E++TYE+ SDLRD+E+VPL ++I +YF  EV+PHV
Sbjct  692  --------------------TGNHNEFVTYESSSDLRDSESVPLEQSIYQYFLDEVKPHV  731

Query  714  AEAWINLDATKIGYEISFNKYFYEHTPLRDIEEVTVDILELEKQSDGLIAEILNL  768
             EAW+NL++ KIGYEISFNKYFY H PLR ++EV+ +I+ LE++++GLIA+IL +
Sbjct  732  DEAWVNLESVKIGYEISFNKYFYRHKPLRSMDEVAKEIIALEQKAEGLIADILGI  786

51) Oscil6304_1854 in NC_019693


> EU272902|18|G17|167832524|ACA01834.1|Vibrio_cholerae_Amazonia_3509|-|21794..24175|-|VPI2_0017c|DNA 
methylase HsdM
Length=793

 Score =  774 bits (2928),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 471/789 (60%), Positives = 616/789 (79%), Gaps = 16/789 (2%)

Query  1    MDHSTHNKLVSFIWSIADDCLRDVFVRGKYRDVILPMFVLRRLDCLLESTKDAVLEEVRF  60
            MDHS HNKLVSFIWSIADDCLRDV+VRGKYRDVILPM VLRRLD LLE++K+AVLEEVRF
Sbjct  1    MDHSVHNKLVSFIWSIADDCLRDVYVRGKYRDVILPMVVLRRLDTLLEPSKEAVLEEVRF  60

Query  61   QREEVGLTVLEPEGLRDASGYVFYNVSDWTLKKLVSTAANNRQILEANLKAYLDGFSSDV  120
            Q+EE+    L+   L  +SGYVFYN S WTL+ L STA+NN+QIL AN+  YL+GFS +V
Sbjct  61   QKEEMNEIELDDAPLCATSGYVFYNTSKWTLQTLFSTATNNQQILLANFEDYLNGFSENV  120

Query  121  KEIIEKFDLRNQIRKMSQSDVLLDVLEKFTSPSINLSPEEVTDPDGRKLPGLTNLGMGYV  180
            KEI+E F+L+ QIR M+  +VLLDV+EKF SP INL+P    DP+G KLP+L+NLGMGYV
Sbjct  121  KEIVECFNLKAQIRHMAGKNVLLDVVEKFVSPYINLTPAVKEDPEGNKLPALSNLGMGYV  180

Query  181  FEELIRRFNEDNNEEAGEHFTPREVIGLMVHLLFIPVKDKLPPTVWVYDGACGSGGMLTE  240
            FEELIR+FNE+NNEEAGEHFTPREVI LM HL+F P+KD+LP ++ VYD ACGSGGMLTE
Sbjct  181  FEELIRKFNEENNEEAGEHFTPREVIELMTHLVFDPIKDNLPLSITVYDPACGSGGMLTE  240

Query  241  SQDFIQDSEGEIASKADVTLFGKEVNPETYAICKSDMMIKGNNPENIKFGSTLATDEFAG  300
            +Q+F+++     AS+ D+ L+GKE+N ETYAICKSDMMIKGNNPENI+ GSTL+TDEF++
Sbjct  241  TQNFVEEKYP--ASNRDIYLYGKEINDETYAICKSDMMIKGNNPENIRVGSTLSTDEFSS  298

Query  301  TKFDFMLENPPYGKSWKTEQKLIMDGKEVLDPRFQVELRDFAGEVKTENAIPRSSDGQLL  360
             +FDFML NPPYGKSW +EQK I +GKEV+D RF+V L+D+ G    ++AIPRSSDGQLL
Sbjct  299  NRFDFMLSNPPYGKSWASEQKHIKEGKEVVDGRFKVKLKDYWGVESEQEAIPRSSDGQLL  358

Query  361  FLMDMVSKMKPLEMSPLGSRIASVHNGSALFTGDAGSGESNIRRYIIENDWLEAIIQLPQ  420
            FLM+MV+KMK+ + SPLGSRIASVHNGS+LFTGDAGSGESNIRRYIIEND L+AI+QLP+
Sbjct  359  FLMEMVTKMKSPQDSPLGSRIASVHNGSSLFTGDAGSGESNIRRYIIENDMLDAIVQLPN  418

Query  421  NLFYNTGISTYIWVLSNHKAPDRKGKVQLIDGSDLYRKLRKNLGAKNCELAPEHIEQITE  480
            NLFYNTGI+TYIW+L+N+K+ +R+GKVQLID+S L+RKLRKNLG KNCE++PEHI +I  
Sbjct  419  NLFYNTGITTYIWLLNNNKPENRQGKVQLIDASLLFRKLRKNLGNKNCEFSPEHIAEIVS  478

Query  481  LYL-------SMKDEG-----ISKVFNNQDFGFYKVTVERPLRLAAQFTSERIASLRFIG  528
             YL       ++ + G      ++VF+NQDFG+YKV +ERP R  AQF ++ I +LRF  
Sbjct  479  TYLENQSVERAIDEKGDPVGIAAQVFKNQDFGYYKVNIERPDRRNAQFRADLIEPLRFEN  538

Query  529  AIAEPMMWVYEQWGDPIYSN--IKDHekeikayiekeeiTITPKNLKVLLSSQAWLGQRD  586
            +  E M  +Y + G+ +Y    +K+ EKEI    E ++I++       LL ++ W+ QR 
Sbjct  539  SQREVMEYLYAEYGEQVYDAGFVKGIEKEITKWCEENDISLNKAAKTKLLDTKNWMKQRT  598

Query  587  LMEIGEKLAYTVGDELWRDFNQFSTAVDDAIADLKLKLSATEKKQIVSAMSWAEESAAPV  646
            L++ + +L   +GDE+  DFNQF   VD  ++ L LKLSA EKK I+ A+SW +E+A  V
Sbjct  599  LVNAASQLHKKIGDEVYNDFNQFKQLVDAELTSLGLKLSAPEKKAILDAVSWYDENAEKV  658

Query  647  VKKYHklkgeklagllaqlNTIEANLADFGYFPTEKAGVWVEYETDSNLRDTENIPLSED  706
            +KK  KLK +KL +LL + +    +L+DFGY+PT +    V YE+ S+LRD+E++PL + 
Sbjct  659  IKKVAKLKQDKLDDLLENYECELEDLPDFGYYPTGNHNEFVTYESSSDLRDSESVPLEQS  718

Query  707  IHGYFLQEVRPHVEDAWLDLSKTAIGYELSFNKYFYKHQPLRSLEEVTAEILQLEAETEG  766
            I  YFL+EV+PHV++AW++L    IGYE+SFNKYFY+H+PLRS++EV+ EI+ LE  +EG
Sbjct  719  IYQYFLDEVKPHVDEAWVNLESVKIGYEISFNKYFYRHKPLRSMDEVAKEIIALEQKAEG  778

Query  767  LLKNLVTFG  775
            L+ +++ ++
Sbjct  779  LIADILGIS  787

52) AM1_4786 in NC_009925


> EU272902|18|G17|167832524|ACA01834.1|Vibrio_cholerae_Amazonia_3509|-|21794..24175|-|VPI2_0017c|DNA 
methylase HsdM
Length=793

 Score =  757 bits (2865),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 467/777 (61%), Positives = 605/777 (78%), Gaps = 19/777 (2%)

Query  1    MDAASQNKLISFIWSIADDCLRDVYVRGKYRDVILPMFVLRRLDCLLEETKDAVMEEVRF  60
            MD + +NKL+SFIWSIADDCLRDVYVRGKYRDVILPM VLRRLD LLE +K+AV+EEVRF
Sbjct  1    MDHSVHNKLVSFIWSIADDCLRDVYVRGKYRDVILPMVVLRRLDTLLEPSKEAVLEEVRF  60

Query  61   QRESVGLTELESGALKDASGYVFYNTSDWTLKRLVETASNNRQILEANFKAYLDGFSENV  120
            Q+E +   EL+ ++L  +SGYVFYNTS WTL+ L  TA+NN+QIL ANF  YL+GFSENV
Sbjct  61   QKEEMNEIELDDAPLCATSGYVFYNTSKWTLQTLFSTATNNQQILLANFEDYLNGFSENV  120

Query  121  KEIIDSFYLRDQIKRMVQADVLLDVLEKFTSPYINFSPTQGEDPDGRKLAGLSNLGMGYV  180
            KEI++ F L+ QI++M   +VLLDV+EKF SPYIN++P+  EDP+G KL++LSNLGMGYV
Sbjct  121  KEIVECFNLKAQIRHMAGKNVLLDVVEKFVSPYINLTPAVKEDPEGNKLPALSNLGMGYV  180

Query  181  FEELIRKFNEENNEEAGEHFTPREVIKLMTHLLFMPVKEQLPPVMLIYDGACGSGGMLTE  240
            FEELIRKFNEENNEEAGEHFTPREVI LMTHL+F P+K++LP  + +YD ACGSGGMLTE
Sbjct  181  FEELIRKFNEENNEEAGEHFTPREVIELMTHLVFDPIKDNLPLSITVYDPACGSGGMLTE  240

Query  241  SQNFISDPEGGIKSDAQVYLYGKEVNPETYGICKSDMMIKGNSPENIKLGSTLAMDEFAG  300
            +QNF+ +   +  S+ ++YLYGKE+N ETY+ICKSDMMIKGN+PENI++GSTL+ DEF++
Sbjct  241  TQNFVEEKYPA--SNRDIYLYGKEINDETYAICKSDMMIKGNNPENIRVGSTLSTDEFSS  298

Query  301  MRFDFMLENPPYGKSYAADQKHILDGKDVLDERFLLPLKDFWDEESLEKATPRSSDGQLL  360
             RFDFML NPPYGKS A++QKHI +GK+V+D RF + LKD+W+ ES + A PRSSDGQLL
Sbjct  299  NRFDFMLSNPPYGKSWASEQKHIKEGKEVVDGRFKVKLKDYWGVESEQEAIPRSSDGQLL  358

Query  361  FLMDMVSKMKPLDQSPAGSRIASVHNGSSLFTGDAGSGESNIRRYIIENDWLEAIVQLPQ  420
            FLM+MV+KMK+ ++SP GSRIASVHNGSSLFTGDAGSGESNIRRYIIEND L+AIVQLP+
Sbjct  359  FLMEMVTKMKSPQDSPLGSRIASVHNGSSLFTGDAGSGESNIRRYIIENDMLDAIVQLPN  418

Query  421  NMFYNTGISTYVWVLSNNKAPERQGKVQLIDRSELYRKLRKNLGAKNCEFAPEQIEKITH  480
            N+FYNTGI+TY+W+L+NNK+ +RQGKVQLID S L+RKLRKNLG KNCEF+PE+I  I  
Sbjct  419  NLFYNTGITTYIWLLNNNKPENRQGKVQLIDASLLFRKLRKNLGNKNCEFSPEHIAEIVS  478

Query  481  LYLDRVHQPTlppsedrelppppISKVFDNQDFGFYKVTVERPLRLLAQFTPERVATLRY  540
             YL+  +Q+   + +++  P    ++VF NQDFG+YKV +ERP R  AQF ++ +  LR+
Sbjct  479  TYLE--NQSVERAIDEKGDPVGIAAQVFKNQDFGYYKVNIERPDRRNAQFRADLIEPLRF  536

Query  541  VPVLAEVMEWAYGEWGDEIYTS--LTDHKQKIEEYLEKEEISLTAKNRKALFTAKTWENQ  598
                 EVME  Y+E G+++Y +  + +  + I    E ++ISL    +  L+ +K W +Q
Sbjct  537  ENSQREVMEYLYAEYGEQVYDAGFVKGIEKEITKWCEENDISLNKAAKTKLLDTKNWMKQ  596

Query  599  RDLMQVAEQLMASVEQEVWHDFNDFAERVNDTLKTLARQLDSKLSASEKRQIFNAVSWRD  658
            R L++ A QL   + +EV +DFN+F + V+  L +L+     KLSA+EK+ I++AVSW D
Sbjct  597  RTLVNAASQLHKKIGDEVYNDFNQFKQLVDAELTSLG----LKLSAPEKKAILDAVSWYD  652

Query  659  EAAARVIKKVhklkgeklaellehlgtteehlaDFGYWPGETAGQWIEYETDSELRDTES  718
            E A +VIKKV KLK +KL +LLE+     E+L+DFGY P     + + YE+ S+LRD+ES
Sbjct  653  ENAEKVIKKVAKLKQDKLDDLLENYECELEDLPDFGYYPTGNHNEFVTYESSSDLRDSES  712

Query  719  VPLNYGQALERGTAQIHGYFLAEVRPHVEDAWIALDSTKIGYEINFNKYFYQHKPLR  775
            VPL+           I  YFL EV+PHV++AW+ L+S KIGYEI+FNKYFY+HKPLR
Sbjct  713  VPLE---------QSIYQYFLDEVKPHVDEAWVNLESVKIGYEISFNKYFYRHKPLR  760

53) BVU_3413 in NC_009614


> EU272902|18|G17|167832524|ACA01834.1|Vibrio_cholerae_Amazonia_3509|-|21794..24175|-|VPI2_0017c|DNA 
methylase HsdM
Length=793

 Score =  604 bits (2281),  Expect = 6e-174, Method: Compositional matrix adjust.
 Identities = 381/781 (49%), Positives = 566/781 (73%), Gaps = 13/781 (1%)

Query  2    EQLIALIWNIADDVLRDVFLRGQYRDVILPMVVLRRLDALLEPTKVAVEQEYKSQIEAGL  61
            ++L+++IW+IADD LRDV++RG+YRDVILPMVVLRRLD+LLEP+K AV +E + Q E   
Sbjct  7    NKLVSFIWSIADDCLRDVYVRGKYRDVILPMVVLRRLDTLLEPSKEAVLEEVRFQKEEMN  66

Query  62   ADNLDEEALKDESGQTYYNLSKWTLNRLKNQSSDNNDINYTNFIEYLNGYSENVKDVLKN  121
              +LD+ +L   SG  +YN SKWTL+ L + +++N++I  +NF +YLNG+SENVK+++  
Sbjct  67   EIELDDAPLCATSGYVFYNTSKWTLQTLFSTATNNQQILLANFEDYLNGFSENVKEIVEC  126

Query  122  FEFYAKVKKLADNDRLISIIERITDPRLNLTDRPATDPDGLPLPAVSNLQMGTlfeellr  181
            F++ A+++ +A+++ L+ ++E++  P +NLT     DP+G  LPA+SNL MG +FEEL+R
Sbjct  127  FNLKAQIRHMAGKNVLLDVVEKFVSPYINLTPAVKEDPEGNKLPALSNLGMGYVFEELIR  186

Query  182  rfneenneeAGEHFTPRDVIELLAKMVFEPVKDNLPKIISLYDPACGSGGMLTEGRDYLL  241
            +FNEENNEEAGEHFTPR+VIEL++ +VF+P+KDNLP  I++YDPACGSGGMLTE ++++ 
Sbjct  187  KFNEENNEEAGEHFTPREVIELMTHLVFDPIKDNLPLSITVYDPACGSGGMLTETQNFVE  246

Query  242  NM-GVTPNAIQMYGTEVNPETYAICKSDFIIKGVDPEGMHRGNTITENHFHNKQFGYMLT  300
            +    +   I +YG E+N ETYAICKSD +IKG +PE ++ G+T++ ++F +++F++ML+
Sbjct  247  EKYPASNRDIYLYGKEINDETYAICKSDMMIKGNNPENIRVGSTLSTDEFSSNRFDFMLS  306

Query  301  NPPYGKSWKEDKKKIYHDKDLLDARFNLKLTNFIGEEEIVDSTPRTSDGQLLFILEEVDK  360
            NPPYGKSW  ++K I ++K+++D+RF++KL ++ G E   ++ PR+SDGQLLF++E V K
Sbjct  307  NPPYGKSWASEQKHIKEGKEVVDGRFKVKLKDYWGVESEQEAIPRSSDGQLLFLMEMVTK  366

Query  361  MKSLEAQPQGSRVASIHNGSSLFTGDAGSGESNIRRYYLIENNLVDAIVQLPNNIFYNTG  420
            MKS +  P GSR+AS+HNGSSLFTGDAGSGESNIRR Y+IEN+++DAIVQLPNN+FYNTG
Sbjct  367  MKSPQDSPLGSRIASVHNGSSLFTGDAGSGESNIRR-YIIENDMLDAIVQLPNNLFYNTG  425

Query  421  ISTYVWLLSNHKQDH---KVQLIDASKAFDKLRKNLGSRNCEVTPKDADDIVRIYM----  473
            I+TY+WLL+N+K ++   KVQLIDAS  F KLRKNLG++NCE +P +  +IV  Y+    
Sbjct  426  ITTYIWLLNNNKPENRQGKVQLIDASLLFRKLRKNLGNKNCEFSPEHIAEIVSTYLENQS  485

Query  474  -NRTECEANDDVRISSKIFDGDDFRYYSVQIERPLRLRCRFSAVKCDELLFDSSMMELSK  532
             +R+  E  D V I++++F  +DF YY V+IERP R   +F A   + L F++S  E+  
Sbjct  486  VERAIDEKGDPVGIAAQVFKNQDFGYYKVNIERPDRRNAQFRADLIEPLRFENSQREVME  545

Query  533  WLYQTYGDKVYSG--LEAEVTDIKEYLNENELKLTDKKFTTLVSAKKWQERRALQQAAMK  590
             LY  YG++VY +  + +   +I    +EN++ L     T L+ +K+W  +R+L +AA +
Sbjct  546  YLYAEYGEQVYDAGFVKGIEKEITKWCEENDISLNKAAKTKLLDTKNWMKQRTLVNAASQ  605

Query  591  LMHKVGTAEYDDYNLFLALNQKAIKELGLKLTAAQLKTILRTNAVQDPTAKPVIAKVLKA  650
            L  K+G   Y+D+N F  L +  +  LGLKL+A++ K+IL + +  D  A  VI KV K 
Sbjct  606  LHKKIGDEVYNDFNQFKQLVDAELTSLGLKLSAPEKKAILDAVSWYDENAEKVIKKVAKL  665

Query  651  KNKDIPAFLATYGIDESLLPDYGYYPQTD-GTYVTYEADSDLRDIEKIPVKEDIWEYVQR  709
            K+  +  +L  Y  +   LPD+GYYP  +   +VTYE+ SDLRD E +P+ + I +Y   
Sbjct  666  KQDKLDDLLENYECELEDLPDFGYYPTGNHNEFVTYESSSDLRDSESVPLEQSIYQYFLD  725

Query  710  EVNPYVSEAWINLPVTKIGCEISFNKYFYKPAQLRSLEENEHDILELDRQSQGFIEALLK  769
            EV+P V EAW+NL   KIG EISFNKYFY+   LRS++E   +I+ L+++++G+I  +L 
Sbjct  726  EVKPHVDEAWVNLESVKIGYEISFNKYFYRHKPLRSMDEVAKEIIALEQKAEGLIADILG  785

Query  770  L  770
            +
Sbjct  786  I  786

54) Bacsa_0512 in NC_015164


> EU272902|18|G17|167832524|ACA01834.1|Vibrio_cholerae_Amazonia_3509|-|21794..24175|-|VPI2_0017c|DNA 
methylase HsdM
Length=793

 Score =  591 bits (2232),  Expect = 4e-170, Method: Compositional matrix adjust.
 Identities = 381/782 (49%), Positives = 562/782 (72%), Gaps = 14/782 (1%)

Query  2    DSSYSQIVALIWNIADDVLRDVFLRGQYRDVILPMVVLRRLDALLEPTKEDVEEEIK---  58
            +S  +++V++IW+IADD LRDV++RG+YRDVILPMVVLRRLD+LLEP+KE V EE++   
Sbjct  3    HSVHNKLVSFIWSIADDCLRDVYVRGKYRDVILPMVVLRRLDTLLEPSKEAVLEEVRFQK  62

Query  59   -ESGVDNIDEGVLKDITRLSYFNTSKWTLNRLKSQASDNNDILYDNFVEYLNGYSENVRD  117
             E    ++D++ L   +   ++NTSKWTL+ L S A++N++IL  NF +YLNG+SENV++
Sbjct  63   EEMNEIELDDAPLCATSGYVFYNTSKWTLQTLFSTATNNQQILLANFEDYLNGFSENVKE  122

Query  118  VLRNFEYYTKARKLADNDRLLSIIERITDPRINLTDKNTIDPDGLPLPALTNVGMGTVfe  177
            ++  F+  ++ R +A+++ LL ++E++  P INLT     DP+G  LPAL+N+GMG VFE
Sbjct  123  IVECFNLKAQIRHMAGKNVLLDVVEKFVSPYINLTPAVKEDPEGNKLPALSNLGMGYVFE  182

Query  178  ellrrfneenneeAGEHFTPRDAISLLAHLVFEPVKENLPKIITLYDPACGSGGMLTESR  237
            EL+R+FNEENNEEAGEHFTPR+ I L++HLVF+P+K+NLP  IT+YDPACGSGGMLTE++
Sbjct  183  ELIRKFNEENNEEAGEHFTPREVIELMTHLVFDPIKDNLPLSITVYDPACGSGGMLTETQ  242

Query  238  EYLLD-LGVRSAAIQLSGTEINPETYAICKSDLIIKGVDPSGIHWGNTITDNSFSDKSFG  296
            +++ +     +  I L G EIN ETYAICKSD++IKG +P  I+ G+T++ + FS + F+
Sbjct  243  NFVEEKYPASNRDIYLYGKEINDETYAICKSDMMIKGNNPENIRVGSTLSTDEFSSNRFD  302

Query  297  YMITNPPYGKSWKEDKKKIYHEKMLLDHRFELTLTNYVGEEEVLDSTPRTSDGQLLFLLE  356
            +M++NPPYGKSW  ++K I + K ++D RF + L +Y G E   ++ PR+SDGQLLFL+E
Sbjct  303  FMLSNPPYGKSWASEQKHIKEGKEVVDGRFKVKLKDYWGVESEQEAIPRSSDGQLLFLME  362

Query  357  EVDKMKPLEFQPQGSRIASIHNGSSLFTGDAGSGESNIRRYLIEKDLVEAIIQLPNNIFY  416
             V KMK+ +  P GSRIAS+HNGSSLFTGDAGSGESNIRRY+IE+D+++AI+QLPNN+FY
Sbjct  363  MVTKMKSPQDSPLGSRIASVHNGSSLFTGDAGSGESNIRRYIIENDMLDAIVQLPNNLFY  422

Query  417  NTGISTYVWMLTNKKKDNRKGKVQLIDASQAFEKLRKNQGSRNCTIEP-YRTDILRVY--  473
            NTGI+TY+W+L N+K +NR+GKVQLIDAS  F KLRKN G++NC + P   ++I+  Y  
Sbjct  423  NTGITTYIWLLNNNKPENRQGKVQLIDASLLFRKLRKNLGNKNCEFSPEHIAEIVSTYLE  482

Query  474  TDFVE---QEANEELKVGSKIFDDDDFRYYNVTIERPLRLRCQFNSLKIDEMLYDSSDIE  530
             + VE   +E  + + +++++F ++DF YY+V IERP R   QF +  I+ + +++S+ E
Sbjct  483  NQSVERAIDEKGDPVGIAAQVFKNQDFGYYKVNIERPDRRNAQFRADLIEPLRFENSQRE  542

Query  531  VSKWLYNTYKDRVF-SGLDSEIPT-IKEYLNDQDIKITDKKLNKLISAKAWKDRQRLMIA  588
            V   LY  Y ++V+ +G+   I   I    +++DI +      KL+ +K W  ++ L+ A
Sbjct  543  VMEYLYAEYGEQVYDAGFVKGIEKEITKWCEENDISLNKAAKTKLLDTKNWMKQRTLVNA  602

Query  589  AKVLMKDMGTDVYMDYNLFSAKVNATAKVLKLETSAAELKTICRAMSVTDSKATPVVKKE  648
            A  L K +G +VY D+N F   V+A    L L  SA+E K+I  A+S  D +A  V+KK 
Sbjct  603  ASQLHKKIGDEVYNDFNQFKQLVDAELTSLGLKLSAPEKKAILDAVSWYDENAEKVIKKV  662

Query  649  HKVNSKDVVMLLETYGVPEEKLSDYG-YHSVKKGMYVEFESDSELRDSEKIPVKEDIYDY  707
             K++   +  LLE Y    E L+D+G Y + +   +V +ES S+LRDSE +P+ + IY+Y
Sbjct  663  AKLKQDKLDDLLENYECELEDLPDFGYYPTGNHNEFVTYESSSDLRDSESVPLEQSIYQY  722

Query  708  FQREVRPYVEDAWINLPQTKIGCEISFNKYFYKPTPLRSLEENERDIIALDEQSQGFIKS  767
            F  EV+P V++AW+NL   KIG EISFNKYFY+  PLRS++E  ++IIAL+++++G+I  
Sbjct  723  FLDEVKPHVDEAWVNLESVKIGYEISFNKYFYRHKPLRSMDEVAKEIIALEQKAEGLIAD  782

Query  768  LF  769
            ++
Sbjct  783  IL  784

55) H681_00040 in NC_020829


> EU272902|18|G17|167832524|ACA01834.1|Vibrio_cholerae_Amazonia_3509|-|21794..24175|-|VPI2_0017c|DNA 
methylase HsdM
Length=793

 Score =  543 bits (2049),  Expect = 1e-155, Method: Compositional matrix adjust.
 Identities = 374/819 (46%), Positives = 536/819 (66%), Gaps = 69/819 (8%)

Query  8    DQSQIKWISDFIWNIADDRLRDVYVRGKYRDVILPFTVLRRLDAVLEATKDAVLERKKLL  67
            D+S  + +  FIW+IADD LRDVYVRGKYRDVILP  VLRRLD++LE++K+AVLE  ++ 
Sbjct  2    DHSVHNKLVSFIWSIADDCLRDVYVRGKYRDVILPMVVLRRLDTLLEPSKEAVLEEVRFQ  61

Query  68   --DAHNVAEQDGALRDAAKQAFYNVSEFTLAKL--KASAAGQRLRDDFIAYLDGFSPNVQ  123
              + +++  +D++L  ++   FYN S  TL  L   A+   Q L  +F  YL+GFS NV+
Sbjct  62   KEEMNEIELDDAPLCATSGYVFYNTSKWTLQTLFSTATNNQQILLANFEDYLNGFSENVK  121

Query  124  EILTKFNFRNQIQKLVDSHVLGYLIDDFLDPEINLAPLPVKDADGRIKLPALDNHGMGTV  183
            EI+  FN++ QI+ + + +VL  +++ F+ P INL+P +VK+     KLPAL N GMG V
Sbjct  122  EIVECFNLKAQIRHMAGKNVLLDVVEKFVSPYINLTP-AVKEDPEGNKLPALSNLGMGYV  180

Query  184  FEELIRRFNEENNEEAGEHFTPRDVVQLMAKLLFLPVADWIESSTYSLYDGSCGTGGMLT  243
            FEELIR+FNEENNEEAGEHFTPR+V++LM+ L+F P+ D +  S  ++YD +CG+GGMLT
Sbjct  181  FEELIRKFNEENNEEAGEHFTPREVIELMTHLVFDPIKDNLPLSI-TVYDPACGSGGMLT  239

Query  244  VAEEVLHELADEHDKEVSIHLFGQEISDETYAICKADLLLKGEGAEAENIVGGADKSTLS  303
             +++ ++E     +++  I L+G+EI+DETYAICK+D+++KG+ +E   +      STLS
Sbjct  240  ETQNFVEEKYPASNRD--IYLYGKEINDETYAICKSDMMIKGNNPENIRVG-----STLS  292

Query  304  ADQFRSREFDFMISNPPYGKSWKTDLERMGGKKEFNDPRFIVSH----AGESEFKLITRS  359
            +D+F S  FDFM+SNPPYGKSW ++  ++   KE  D RF V      + ESE   I RS
Sbjct  293  TDEFSSNRFDFMLSNPPYGKSWASEQKHIKEGKEVVDGRFKVKLKDYWGVESEQEAIPRS  352

Query  360  SDGQLMFLVNKLQKMK--HNTPLGSRIALVHNGSALFTGDAGQGESNIRRWVLENDWLEA  417
            SDGQL+FL++ + KMK  +++PLGSRIA VHNGS+LFTGDAG GESNIRR ++END L+A
Sbjct  353  SDGQLLFLMEMVTKMKSPQDSPLGSRIASVHNGSSLFTGDAGSGESNIRRYIIENDMLDA  412

Query  418  IIALPLNIFYNTGIATYIWVLANKKAQARRGKVQLIDASQWFQPLRRNLGKKNCELSDSD  477
            I+ LP N+FYNTGI+TYIW+L N+K++ R+GKVQLIDAS  F+ LR+NLG+KNCE+S  +
Sbjct  413  IVQLPNNLFYNTGITTYIWLLNNNKPENRQGKVQLIDASLLFRKLRKNLGNKNCEFSPEH  472

Query  478  VACILDLYLGE-----------AQETAQSKWFDTQDFGYWKITVERPLRLKSQLSDERIE  526
            +A I+  YL +                 ++ F  QDFGY K+ +ERP R ++Q+  + IE
Sbjct  473  IAEIVSTYLENQSVERAIDEKGDPVGIAAQVFKNQDFGYYKVNIERPDRRNAQFRADLIE  532

Query  527  PLRFASSDEALRAEIYATHGEALY-SEFAK-RKTAIEAWLKgedenededsedgdsddds  584
            PLRF +S+  +   +YA  GE +Y + F K     I  W                     
Sbjct  533  PLRFENSQREVMEYLYAEYGEQVYDAGFVKGIEKEITKW---------------------  571

Query  585  eTPATRKAVPAKRRKKLLDASTWQRDKRLLEVAQRARKALGSAVFDDHNEFRTCFDAALK  644
                   ++    + KLLD+  W +++ L++ A + +K +G  V++D N+F+   DA L 
Sbjct  572  -CEENDISLNKAAKTKLLDTKNWMKQRTLVNAASQLHKKIGDEVYNDFNQFKQLVDAELT  630

Query  645  AQGDKLSASEKKAIYKAVSWRDETAPPVIAKRTKLKAS--DPFVGNYDGRYLLDE-----  697
            + G KLSA+EKKAI  AVSW DE A  VI K +KLK    D ++ NY+    L++     
Sbjct  631  SLGLKLSAPEKKAILDAVSWYDENAEKVIKKVAKLKQDKLDDLLENYECE--LEDLPDFG  688

Query  698  ----HNHREVVEYESDADLRDTEQVPLKEPGGIDAFFAREVRPHTPDAWIATDKTQIGYE  753
                 NH E V YES +DLRD+E VPL +  +I  +F  EV+PH  +AW+  +  +IGYE
Sbjct  689  YYPTGNHNEFVTYESSSDLRDSESVPLEQ--SIYQYFLDEVKPHVDEAWVNLESVKIGYE  746

Query  754  ISFARYFYKPTPLRTLAEIRADILALEQQSEGLLHKIVG  792
            ISF +YFY+  PLR++ E+  +I+ALEQ++EGL+  I+G
Sbjct  747  ISFNKYFYRHKPLRSMDEVAKEIIALEQKAEGLIADILG  785

56) Ilyop_1055 in NC_014632


> EU272902|18|G17|167832524|ACA01834.1|Vibrio_cholerae_Amazonia_3509|-|21794..24175|-|VPI2_0017c|DNA 
methylase HsdM
Length=793

 Score =  538 bits (2029),  Expect = 7e-154, Method: Compositional matrix adjust.
 Identities = 369/804 (46%), Positives = 545/804 (68%), Gaps = 84/804 (10%)

Query  257  MDHKVHNKIVSYIWSIADDVLRDIFVRGKYRDVILPFTVLRRIDILLEESKEKVLEMNKF  316
            MDH VHNK+VS+IWSIADD LRD++VRGKYRDVILP  VLRR+D LLE SKE VLE  +F
Sbjct  1    MDHSVHNKLVSFIWSIADDCLRDVYVRGKYRDVILPMVVLRRLDTLLEPSKEAVLEEVRF  60

Query  317  FEENNIN---DKSGLEKITGYPFYNTSPFTMGKNSLKDSEYPFVSLLSDPDKIDSNLEEY  373
              E+  +   D + L   +GY FYNTS  T+  ++L      F +  ++ + + +N+E+Y
Sbjct  61   QKEEMNEIELDDAPLCATSGYVFYNTSKWTL--QTL------FSTATNNQQILLANFEDY  112

Query  374  LDGFSPNIQEIISKFKVRNQLETMQDAGITFGLIDKLTSGSINLSPYEVKNSKGEILPAL  433
            L+GFS N++EI+  F+++ Q+  M +  + +++++K+ S  INL+P    ++ G+ LPAL
Sbjct  113  LNGFSENVKEIVECFNLKAQIRHMAGKNVLLDVVEKFVSPYINLTPAVKEDPEGNKLPAL  172

Query  434  TNLGMGYVFEELIRKFNEENNEEAGEHFTPREIIKLMTHIIFEPIKDILKEREGARFSIY  493
            +NLGMGYVFEELIRKFNEENNEEAGEHFTPRE+I LMTH++F+PIKD L       +++Y
Sbjct  173  SNLGMGYVFEELIRKFNEENNEEAGEHFTPREVIELMTHLVFDPIKDNL----PLSITVY  228

Query  494  DPACGSGGMLTEAEDFALK--ITDNKCIFSLFGQEVNPETWAICTGDMLIKGEKASNIGY  551
            DPACGSGGMLTE+++F      + N+ I+ L+G+E+N ET AIC +DM+IKG+++ NI  
Sbjct  229  DPACGSGGMLTETQNFVEEKYPASNRDIY-LYGKEINDETYAICKSDMMIKGNNPENIRV  287

Query  552  GSTLSNDEFKGHKFDFILSNPPYGKSWKNDVDAIVENRGKKGKEIIKDPRFKV-------  604
            GSTLS DEF +++FDF+LSNPPYGKSW ++     +++ K GKE++ D RFKV       
Sbjct  288  GSTLSTDEFSSNRFDFMLSNPPYGKSWASE-----QKHIKEGKEVV-DGRFKVKLKDYWG  341

Query  605  ------GLPTISDGQLLFLVNMISKMKN--DTELGSRIASVHNGSSLFTGDAGQGESEIR  656
                  ++P  SDGQLLFL++M++KMK+  D+ LGSRIASVHNGSSLFTGDAG GES+IR
Sbjct  342  VESEQEAIPRSSDGQLLFLMEMVTKMKSPQDSPLGSRIASVHNGSSLFTGDAGSGESNIR  401

Query  657  KMILENDLLECIIALSTNIFYNTGIPTYIWILSNRKEERRKGKVQLINAIDIYTPLRKNL  716
            + I+END+L+ I+ L+ N+FYNTGI TYIW+L+N K E R+GKVQLI+A  ++  LRKNL
Sbjct  402  RYIIENDMLDAIVQLPNNLFYNTGITTYIWLLNNNKPENRQGKVQLIDASLLFRKLRKNL  461

Query  717  GQKNCELTKTQIDSITKIYLDFKKTE------------TSKIFDNEDFGYNKIIVERPLR  764
            G+KNCE++  +I  I   YL+ +  E            ++++F N+DFGY K+ +ERP R
Sbjct  462  GNKNCEFSPEHIAEIVSTYLENQSVERAIDEKGDPVGIAAQVFKNQDFGYYKVNIERPDR  521

Query  765  LKAKITNEAIESLRYEKTIIDEAKWIYRKYGDKVYDG--LKDVkkdienwiekneikiSP  822
             +A++  + IE+LR+E++  +    +Y  YG++VYD+  +K++ K+I +W E N+I ++ 
Sbjct  522  RNAQFRADLIEPLRFENSQREVMEYLYAEYGEQVYDAGFVKGIEKEITKWCEENDISLNK  581

Query  823  ANKKKIFDVNVWKSQEELMKITEQLLEEIGEIEFDNFNTFKDLIGDTLNkldikigkkdl  882
            A K K++D + W  Q  L++ + QL   IG+  +++FN FK+L++  L  L++K++  + 
Sbjct  582  AAKTKLLDTKNWMKQRTLVNAASQLHKKIGDEVYNDFNQFKQLVDAELTSLGLKLSAPEK  641

Query  883  dliFNAITWKDEEGEPVIKKVEK-------------------------------DGTIIY  911
              I++A++W DE++E VIKKV K                               +  + Y
Sbjct  642  KAILDAVSWYDENAEKVIKKVAKLKQDKLDDLLENYECELEDLPDFGYYPTGNHNEFVTY  701

Query  912  EADSDLRDSESVPLNEDIHEYFEREVLNYIPDAWIDESKTQKGYSISFTRYFYNFTPPRS  971
            E+ SDLRDSESVPL++ I +YF  EV   + +AW++    + GY ISF +YFY   P RS
Sbjct  702  ESSSDLRDSESVPLEQSIYQYFLDEVKPHVDEAWVNLESVKIGYEISFNKYFYRHKPLRS  761

Query  972  LEAIASEIEKLQEETEGIMEEFLN  995
            ++ +A EI  L++ +EG++ ++L 
Sbjct  762  MDEVAKEIIALEQKAEGLIADILG  785

57) Glov_2201 in NC_010814


> EU272902|18|G17|167832524|ACA01834.1|Vibrio_cholerae_Amazonia_3509|-|21794..24175|-|VPI2_0017c|DNA 
methylase HsdM
Length=793

 Score =  537 bits (2028),  Expect = 6e-154, Method: Compositional matrix adjust.
 Identities = 371/810 (46%), Positives = 554/810 (69%), Gaps = 63/810 (7%)

Query  1    MDQATHNKIVSFIWGIADDVLRDLFKRGKYPDVILPMCVLRRLDAVLEPTKQAVLDT---  57
            MD++ HNK+VSFIW+IADD LRD++ RGKY DVILPM VLRRLD++LEP+K+AVL+    
Sbjct  1    MDHSVHNKLVSFIWSIADDCLRDVYVRGKYRDVILPMVVLRRLDTLLEPSKEAVLEEVRF  60

Query  58   -KQMLDDAGITEQKAALCEAAGQAFYNTSRFTLRDL--RSRANQQQLKLDFEDYLDGFSQ  114
             K+ +++  + +  A+LC ++G  FYNTS+ TL+ L   +  NQQ L  +FEDYL+GFS+
Sbjct  61   QKEEMNEIELDD--APLCATSGYVFYNTSKWTLQTLFSTATNNQQILLANFEDYLNGFSE  118

Query  115  NVQDILENFKFRNQISTLSKADAIGTLIEKFLDPDINVSPNPVLNSDGSVRLPAMDNHSM  174
            NV++I+E F+++ QI  ++  + +  ++EKF+ P IN++P    +++G+ +LPA+ N +M
Sbjct  119  NVKEIVECFNLKAQIRHMAGKNVLLDVVEKFVSPYINLTPAVKEDPEGN-KLPALSNLGM  177

Query  175  GTVFEELVRKFNEDNNEEAGEHWTPRDAVKLMARLIFLPIADQVQSGSYQLYDGACGTGG  234
            G VFEEL+RKFNE+NNEEAGEH TPR+ + LM++L+F PI D++  +   +YD ACG+GG
Sbjct  178  GYVFEELIRKFNEENNEEAGEHFTPREVIELMTHLVFDPIKDNLPLSI-TVYDPACGSGG  236

Query  235  MltlaeetlleltaaQDKQVKTYLFGQEINPETYAICKADMLMKGEGENADHIVGGAEWS  294
            MLT +++ + E  +A ++++  YL+G+EIN ETYAICK+DM++KG+  N+++I  G   S
Sbjct  237  MLTETQNFVEEKYPASNRDI--YLYGKEINDETYAICKSDMMIKGN--NPENIRVG---S  289

Query  295  TLAHDAFPAHEFDFMLSNPPYGKSWKKDLDTMGGKDGIRDSRFKITHAD----DTDYSLI  350
            TL+ D F+++ FDFMLSNPPYGKSW  +   +     + D+RFK+   D    +++   I
Sbjct  290  TLSTDEFSSNRFDFMLSNPPYGKSWASEQKHIKEGKEVVDGRFKVKLKDYWGVESEQEAI  349

Query  351  TRSSDGQMMFLANMVAKMN--HTSRLGSRIAEVHNGSSLFTGDAGQGESNIRRWIIEKDW  408
             RSSDGQ++FL +MV+KM+  + S LGSRIA VHNGSSLFTGDAG GESNIRR IIE+D 
Sbjct  350  PRSSDGQLLFLMEMVTKMKSPQDSPLGSRIASVHNGSSLFTGDAGSGESNIRRYIIENDM  409

Query  409  LEAIVALPLNLFYNTGIATYIWVLSNRKPDHRKGKVQLIDATAWFKPLRKNLGKKNCELS  468
            L+AIV LP NLFYNTGI+TYIW+L+N KP++R+GKVQLIDA+  F+ LRKNLG+KNCE+S
Sbjct  410  LDAIVQLPNNLFYNTGITTYIWLLNNNKPENRQGKVQLIDASLLFRKLRKNLGNKNCEFS  469

Query  469  DDDIQRICDTY-------QSFTESEQ-----SKIFQNKAFGYWKVTVERPLRLHSQLSLP  516
             ++I  I  TY       +++ E  +     +++F+N+ FGY KV +ERP R ++Q+   
Sbjct  470  PEHIAEIVSTYLENQSVERAIDEKGDPVGIAAQVFKNQDFGYYKVNIERPDRRNAQFRAD  529

Query  517  AIESLRFASGDEEIRTQLYEEFGDVLFEQ-F-SSIEKELAKRLaewgagddegeddeaPR  574
             IE+LRF +++ E+   LY E+G+ +++  F  +IEKE++K+              E   
Sbjct  530  LIEPLRFENSQREVMEYLYAEYGEQVYDAGFVKGIEKEITKW-------------CEEND  576

Query  575  KGLSEkkkkkllDAGTWARDARLMETAQSLRDLLGGDLYEDHNRFRIDVDTALKKLGRKL  634
             +L+   K KLLD+  W ++  L+++A  L+  +G+++Y+D N+F+  VD+ L  LG KL
Sbjct  577  ISLNKAAKTKLLDTKNWMKQRTLVNAASQLHKKIGDEVYNDFNQFKQLVDAELTSLGLKL  636

Query  635  PAAELKLILKAVSWRVETAPPVIARLHKPGKATPDPLRGLYPVTID-----------GKA  683
            +A+E K IL AVSW  E A  VI ++ K  +   D L   Y   ++              
Sbjct  637  SAPEKKAILDAVSWYDENAEKVIKKVAKLKQDKLDDLLENYECELEDLPDFGYYPTGNHN  696

Query  684  CVVEYEPDTDLRDTEQVPLLEDGGIEAFIQREVLPYTPDAWLDESKTKIGYEISFTRHFY  743
              V YE+ +DLRD+E VPL  + +I  ++  EV P   +AW++    KIGYEISF + FY
Sbjct  697  EFVTYESSSDLRDSESVPL--EQSIYQYFLDEVKPHVDEAWVNLESVKIGYEISFNKYFY  754

Query  744  KPQPLRTLEEIRADILAVEQEAEGLLDDLL  773
            + +PLR+++E+  +I+A+EQ AEGL+ D+L
Sbjct  755  RHKPLRSMDEVAKEIIALEQKAEGLIADIL  784

58) CAP2UW1_4292 in NC_013194


> EU272902|18|G17|167832524|ACA01834.1|Vibrio_cholerae_Amazonia_3509|-|21794..24175|-|VPI2_0017c|DNA 
methylase HsdM
Length=793

 Score =  536 bits (2021),  Expect = 2e-153, Method: Compositional matrix adjust.
 Identities = 355/808 (44%), Positives = 544/808 (68%), Gaps = 69/808 (8%)

Query  1    MDQATHNKIVSFIWGIADDVLRDLFKRGKYPDVILPMCVIRRMDAVLEPTKQSVLDTRRM  60
            MD++ HNK+VSFIW+IADD LRD++ RGKY DVILPM V+RR+D++LEP+K++VL+  R 
Sbjct  1    MDHSVHNKLVSFIWSIADDCLRDVYVRGKYRDVILPMVVLRRLDTLLEPSKEAVLEEVRF  60

Query  61   L--DAAGITEQRAALCDAAGQAFYNTSRFTLRDL--KSRGSQQRLLADFEDYLNGFSANV  116
               +   I  + A+LC ++G  FYNTS+ TL+ L   +  +QQ LLA+FEDYLNGFS NV
Sbjct  61   QKEEMNEIELDDAPLCATSGYVFYNTSKWTLQTLFSTATNNQQILLANFEDYLNGFSENV  120

Query  117  QDILDNFKFRNQLQTLSRADAIGTLINKFLDPDIDLSPA-----------GIDNHSMGTV  165
            ++I++ F+++ Q++ ++  + +  +++KF+ P I+L+PA           ++ N +MG V
Sbjct  121  KEIVECFNLKAQIRHMAGKNVLLDVVEKFVSPYINLTPAVKEDPEGNKLPALSNLGMGYV  180

Query  166  FEELVRKFNEENNEEAGEHWTPRDAVRLMANLVFRPIESAIRSGTYLLYDCACGTGGMLT  225
            FEEL+RKFNEENNEEAGEH TPR+ + LM++LVF PI   +  +   +YD ACG+GGMLT
Sbjct  181  FEELIRKFNEENNEEAGEHFTPREVIELMTHLVFDPIKDNLPLSI-TVYDPACGSGGMLT  239

Query  226  VAEETLTAIAAGRGQQVRCLLYGQEINPETYAVCKADMLLKGEGESADHIVGGAEWSTLA  285
             +++ +    ++  +++   LYG+EIN ETYA+CK+DM++KG+  ++++I  G   STL+
Sbjct  240  ETQNFVEEKYPASNRDI--YLYGKEINDETYAICKSDMMIKGN--NPENIRVG---STLS  292

Query  286  HDAFPAREFDFMLANPPYGKSWKKDLEAMGGKDGMRDPRFKVMHQG-----EELSLVTRS  340
             D F++  FDFML+NPPYGKSW  +   +     + D RFKV  ++      E   + RS
Sbjct  293  TDEFSSNRFDFMLSNPPYGKSWASEQKHIKEGKEVVDGRFKVKLKDYWGVESEQEAIPRS  352

Query  341  SDGQMLFLANMASKMNG--QSALGSRIAEVHNGSSLFTGDAGQGESNIRRWLIENDWLEA  398
            SDGQ+LFL +M +KM++  +S+LGSRIA VHNGSSLFTGDAG GESNIRR +IEND L+A
Sbjct  353  SDGQLLFLMEMVTKMKSPQDSPLGSRIASVHNGSSLFTGDAGSGESNIRRYIIENDMLDA  412

Query  399  IVALPLNLFYNTGIATYIWVLSNRKPAHRQGRVQLIDASQWFKPLRKNLGKKNCELSPED  458
            IV LP NLFYNTGI+TYIW+L+N KP +RQG+VQLIDAS  F+ LRKNLG+KNCE+SPE+
Sbjct  413  IVQLPNNLFYNTGITTYIWLLNNNKPENRQGKVQLIDASLLFRKLRKNLGNKNCEFSPEH  472

Query  459  IERISRSFLD-------FAETPE-----SKIFPNAAFGYWKVTVERPLRLYSQLSLKAIE  506
            I  I  ++L+       + E  +     +++F N  FGY KV +ERP R  +Q+    IE
Sbjct  473  IAEIVSTYLENQSVERAIDEKGDPVGIAAQVFKNQDFGYYKVNIERPDRRNAQFRADLIE  532

Query  507  TLRFNSGDEDLRATLYEEFGDDLFTRFSAVSAALEKRLADWgssddsegeddegggTKKG  566
             LRF++++ ++   LY E+G++++   ++   ++EK ++ W                  +
Sbjct  533  PLRFENSQREVMEYLYAEYGEQVYD--AGFVKGIEKEITKW------------CEENDIS  578

Query  567  LPERQKKKLLDARTWERDGRLVDVATRLRVLLGEALFDDHNAFRDRVDTalkaagiklaa  626
            L    K KLLD++ W ++  LV+ A++L+  +G+ +++D N F++ VD+ L + G+KL+A
Sbjct  579  LNKAAKTKLLDTKNWMKQRTLVNAASQLHKKIGDEVYNDFNQFKQLVDAELTSLGLKLSA  638

Query  627  adlkQILKVVSWRDESAPPVIARVHKPGKLRAEPLRGFYEATVD-----------GRSSI  675
            ++ K IL  VSW DE+A  VI +V K  + + + L   YE  ++            ++ +
Sbjct  639  PEKKAILDAVSWYDENAEKVIKKVAKLKQDKLDDLLENYECELEDLPDFGYYPTGNHNEF  698

Query  676  VEYEPDADLRDTEQVPLLEDGGIAAFIRREVLPYTPDAWIKEDATKIGYEISFTRHFYKP  735
            V YE+ +DLRD+E VPL  + +I  ++  EV P   +AW++ ++ KIGYEISF + FY+ 
Sbjct  699  VTYESSSDLRDSESVPL--EQSIYQYFLDEVKPHVDEAWVNLESVKIGYEISFNKYFYRH  756

Query  736  QPLRTLEEISADILAIEKEAEGLLDGLL  763
            +PLR+++E++ +I+A+E+ AEGL+ ++L
Sbjct  757  KPLRSMDEVAKEIIALEQKAEGLIADIL  784

59) PSJM300_00040 in NC_018177


> EU272902|18|G17|167832524|ACA01834.1|Vibrio_cholerae_Amazonia_3509|-|21794..24175|-|VPI2_0017c|DNA 
methylase HsdM
Length=793

 Score =  533 bits (2013),  Expect = 9e-153, Method: Compositional matrix adjust.
 Identities = 370/819 (46%), Positives = 540/819 (66%), Gaps = 69/819 (8%)

Query  8    DQSQIKWISDFIWNIADDRLRDVYVRGKYRDVILPFTVLRRLDAVLESTKDAVLERKKFL  67
            D+S  + +  FIW+IADD LRDVYVRGKYRDVILP  VLRRLD++LE++K+AVLE  +F 
Sbjct  2    DHSVHNKLVSFIWSIADDCLRDVYVRGKYRDVILPMVVLRRLDTLLEPSKEAVLEEVRFQ  61

Query  68   --DTHKVAEQDGALRMAAGQAFYNVSEFTLAKL--KASAAGQRLRDDFTDYLDGFSPNVQ  123
              + + +  +D++L  ++G  FYN S  TL  L   A+   Q L  +F DYL+GFS NV+
Sbjct  62   KEEMNEIELDDAPLCATSGYVFYNTSKWTLQTLFSTATNNQQILLANFEDYLNGFSENVK  121

Query  124  EILAKFNFRNQIQKLVDSHVLGYLIEDFLDPEINLSPLPVKDTDGSIKLPALDNHGMGTV  183
            EI+  FN++ QI+ + + +VL  ++E F+ P INL+P +VK+   + KLPAL N GMG V
Sbjct  122  EIVECFNLKAQIRHMAGKNVLLDVVEKFVSPYINLTP-AVKEDPEGNKLPALSNLGMGYV  180

Query  184  FEELIRRFNEDNNLEAGEHYTPRDVVKLMAKLLFLPVANLIESSTYSLYDGSCGTGGMLT  243
            FEELIR+FNE+NN EAGEH+TPR+V+ LM+ L+F P+ + +  S  ++YD +CG+GGMLT
Sbjct  181  FEELIRKFNEENNEEAGEHFTPREVIELMTHLVFDPIKDNLPLSI-TVYDPACGSGGMLT  239

Query  244  VaeealhelaeehGKEVSIHLFGQEISDETYAICKADLLLKGEGAEAENIVGGADKSTLS  303
             +++ ++E      ++  I L+G+EI+DETYAICK+D+++KG+ +E   +      STLS
Sbjct  240  ETQNFVEEKYPASNRD--IYLYGKEINDETYAICKSDMMIKGNNPENIRVG-----STLS  292

Query  304  SDHFRSREFDFMISNPPYGKSWKTDLERMGGRKEFSDPRFIVSH----AGESEFKLITRS  359
            +D+F S  FDFM+SNPPYGKSW ++  ++   KE  D RF V      + ESE   I RS
Sbjct  293  TDEFSSNRFDFMLSNPPYGKSWASEQKHIKEGKEVVDGRFKVKLKDYWGVESEQEAIPRS  352

Query  360  SDGQLMFLVNKLQKMK--HNTPLGSRIALVHNGSALFTGDAGQGESNIRRWVLENDWLES  417
            SDGQL+FL++ + KMK  +++PLGSRIA VHNGS+LFTGDAG GESNIRR ++END L++
Sbjct  353  SDGQLLFLMEMVTKMKSPQDSPLGSRIASVHNGSSLFTGDAGSGESNIRRYIIENDMLDA  412

Query  418  IIALPLNIFYNTGIATYIWVLANKKAEERRGKVQLIDASQWFQPLRRNLGKKNCELSDAD  477
            I+ LP N+FYNTGI+TYIW+L N+K+E+R+GKVQLIDAS  F+ LR+NLG+KNCE+S  +
Sbjct  413  IVQLPNNLFYNTGITTYIWLLNNNKPENRQGKVQLIDASLLFRKLRKNLGNKNCEFSPEH  472

Query  478  IACILDLYLGE--AQQTVQSK---------WFDTQDFGYWKITVERPLRLKSQLSDERIE  526
            IA I+  YL +   +++++ K          F  QDFGY K+ +ERP R ++Q+  + IE
Sbjct  473  IAEIVSTYLENQSVERAIDEKGDPVGIAAQVFKNQDFGYYKVNIERPDRRNAQFRADLIE  532

Query  527  PLRFASGDEVLRAEIYATHGEALY-TDFIN-RKPAIEAWLKGedenedddsedsdssdds  584
            PLRF +++  +   +YA  GE +Y ++F++     I  W                     
Sbjct  533  PLRFENSQREVMEYLYAEYGEQVYDAGFVKGIEKEITKW---------------------  571

Query  585  eapaarkavpakrrkkLLDASTWQRDKALMEVAQRAQKALGSAVFDDHNDFRTRFGEALK  644
                   ++    + KLLD+  W ++++L++ A + +K +G  V++D N+F+   +  L 
Sbjct  572  -CEENDISLNKAAKTKLLDTKNWMKQRTLVNAASQLHKKIGDEVYNDFNQFKQLVDAELT  630

Query  645  AEGDKLGAPEKKVIYKAVSWRDETAPPVIAKRTKLKAT--DAFVANND---------GRF  693
            + G KL+APEKK I  AVSW DE A  VI K +KLK    D ++ N +         G +
Sbjct  631  SLGLKLSAPEKKAILDAVSWYDENAEKVIKKVAKLKQDKLDDLLENYECELEDLPDFGYY  690

Query  694  LVGEDKHREVVEYESDTDLRDTEQVPLKEPGGIDAFFAREVLPHASDAWIAMDKTQIGYE  753
              G+  H E V YES +DLRD+E VPL +  +I  +F  EV PH  +AW+ ++  +IGYE
Sbjct  691  PTGN--HNEFVTYESSSDLRDSESVPLEQ--SIYQYFLDEVKPHVDEAWVNLESVKIGYE  746

Query  754  ISFARYFYKPAPLRTLKEIRADILALEQQSEGLLHKIVG  792
            ISF +YFY+  PLR++ E+  +I+ALEQ++EGL+  I+G
Sbjct  747  ISFNKYFYRHKPLRSMDEVAKEIIALEQKAEGLIADILG  785

60) Alide2_2051 in NC_015422


> EU272902|18|G17|167832524|ACA01834.1|Vibrio_cholerae_Amazonia_3509|-|21794..24175|-|VPI2_0017c|DNA 
methylase HsdM
Length=793

 Score =  532 bits (2009),  Expect = 2e-152, Method: Compositional matrix adjust.
 Identities = 363/808 (45%), Positives = 528/808 (66%), Gaps = 67/808 (8%)

Query  18   FIWNIADDRLRDVYVRGKYRDVILPFTVLRRLDAVLEATKDAVLERKKFL--DTHKVAEQ  75
            FIW+IADD LRDVYVRGKYRDVILP  VLRRLD++LE++K+AVLE  +F   + + +  +
Sbjct  12   FIWSIADDCLRDVYVRGKYRDVILPMVVLRRLDTLLEPSKEAVLEEVRFQKEEMNEIELD  71

Query  76   DGALRMAAGQAFYNVSEFTLAKL--KASAAGQRLRDDFIAYLDGFSPNVQEILTKFNFRN  133
            D++L  ++G  FYN S  TL  L   A+   Q L  +F  YL+GFS NV+EI+  FN++ 
Sbjct  72   DAPLCATSGYVFYNTSKWTLQTLFSTATNNQQILLANFEDYLNGFSENVKEIVECFNLKA  131

Query  134  QIQKLVDSHVLGYLIDDFLDPEVNLAPLPVKDADGRIKLPALDNHGMGTVFEELIRRFNE  193
            QI+ + + +VL  +++ F+ P +NL+P +VK+     KLPAL N GMG VFEELIR+FNE
Sbjct  132  QIRHMAGKNVLLDVVEKFVSPYINLTP-AVKEDPEGNKLPALSNLGMGYVFEELIRKFNE  190

Query  194  DNNEEAGEHFTPRDVVQLMAKLLFLPVADRIDSSTYSLYDGSCGTGGMLTVaeealhela  253
            +NNEEAGEHFTPR+V++LM+ L+F P+ D +  S  ++YD +CG+GGMLT +++ ++E  
Sbjct  191  ENNEEAGEHFTPREVIELMTHLVFDPIKDNLPLSI-TVYDPACGSGGMLTETQNFVEEKY  249

Query  254  eehGKEVSIHLFGQEISDETYAICKADLLLKGEGAEAENIVGGADKSTLSADQFRSREFD  313
                ++  I L+G+EI+DETYAICK+D+++KG+ +E   +      STLS+D+F S  FD
Sbjct  250  PASNRD--IYLYGKEINDETYAICKSDMMIKGNNPENIRVG-----STLSTDEFSSNRFD  302

Query  314  FMISNPPYGKSWKTDLERMGGKKEFNDPRFIVSH----AGNAEFKLLTRSSDGQLMFQVN  369
            FM+SNPPYGKSW ++  ++   KE  D RF V      + ++E   + RSSDGQL+F ++
Sbjct  303  FMLSNPPYGKSWASEQKHIKEGKEVVDGRFKVKLKDYWGVESEQEAIPRSSDGQLLFLME  362

Query  370  KLQKMK--HNTPLGSRIALVHNGSALFTGDAGQGESNIRRWVLENDWLEAIIALPLNIFY  427
             + KMK  +++PLGSRIA VHNGS+LFTGDAG GESNIRR ++END L+AI+ LP N+FY
Sbjct  363  MVTKMKSPQDSPLGSRIASVHNGSSLFTGDAGSGESNIRRYIIENDMLDAIVQLPNNLFY  422

Query  428  NTGIATYIWVLANKKAEARRGKVQLIDASGWFQPLRRNLGKKNCELADADIARILDLYLG  487
            NTGI+TYIW+L N+K+E R+GKVQLIDAS  F+ LR+NLG+KNCE++  +IA I+  YL 
Sbjct  423  NTGITTYIWLLNNNKPENRQGKVQLIDASLLFRKLRKNLGNKNCEFSPEHIAEIVSTYLE  482

Query  488  E-----------AQETAQSKWFDTQDFGYWKITVERPLRLKSQLSDERIEPLRFATGDEA  536
            +                 ++ F  QDFGY K+ +ERP R ++Q+  + IEPLRF  ++  
Sbjct  483  NQSVERAIDEKGDPVGIAAQVFKNQDFGYYKVNIERPDRRNAQFRADLIEPLRFENSQRE  542

Query  537  LRAEIYATHGDALY-TEFAK-RKPAIEAWLKgedenedddsedsdsgddseapaarkavp  594
            +   +YA  G+ +Y + F K     I  W                            ++ 
Sbjct  543  VMEYLYAEYGEQVYDAGFVKGIEKEITKW----------------------CEENDISLN  580

Query  595  akrrkkLLDATTWQRDKGLMEVAQRAQQALGSAVFDDHNEFRTRFDAALKARGEKLGAPE  654
               + KLLD+  W +++ L++ A + ++ +G  V++D N+F+   DA L + G KL+APE
Sbjct  581  KAAKTKLLDTKNWMKQRTLVNAASQLHKKIGDEVYNDFNQFKQLVDAELTSLGLKLSAPE  640

Query  655  KKAIYKAVSWRDEAAPPVIAKRSKLKAG------EHFEPGFDG----AYLETVGKDRFMV  704
            KKAI  AVSW DE A  VI K +KLK +      E++E  +++    +Y  T   + F V
Sbjct  641  KKAILDAVSWYDENAEKVIKKVAKLKQDKLDDLLENYECELEDLPDFGYYPTGNHNEF-V  699

Query  705  EYEPDSELRDTEQVPLKEPGGIDAFFAREVLPHAPDAWIATDKTQIGYEISFARYFYKPA  764
             YE+ S+LRD+E VPL +  +I  +F  EV PH  +AW+  +  +IGYEISF +YFY+  
Sbjct  700  TYESSSDLRDSESVPLEQ--SIYQYFLDEVKPHVDEAWVNLESVKIGYEISFNKYFYRHK  757

Query  765  PLRTLAEIRADILALEQQSEGLLHKIVG  792
            PLR++ E+  +I+ALEQ++EGL+  I+G
Sbjct  758  PLRSMDEVAKEIIALEQKAEGLIADILG  785

61) MCA0278 in NC_002977


> EU272902|18|G17|167832524|ACA01834.1|Vibrio_cholerae_Amazonia_3509|-|21794..24175|-|VPI2_0017c|DNA 
methylase HsdM
Length=793

 Score =  531 bits (2002),  Expect = 7e-152, Method: Compositional matrix adjust.
 Identities = 370/815 (46%), Positives = 532/815 (66%), Gaps = 65/815 (7%)

Query  8    DQSQIKWISDFIWNIADNRLRDVYVRGKYRDVILPFTVLRRLDAVLEETKQKVLERKRFL  67
            D+S  + +  FIW+IAD+ LRDVYVRGKYRDVILP  VLRRLD++LE +K+ VLE  RF 
Sbjct  2    DHSVHNKLVSFIWSIADDCLRDVYVRGKYRDVILPMVVLRRLDTLLEPSKEAVLEEVRFQ  61

Query  68   --DKNNVAEQDGALRMAAGQAFYNVSEFTLAKL--KASSQGQRLREDFIAYLDGFSPNVQ  123
              + N++  +D++L  ++G  FYN S  TL  L   A+++ Q L  +F  YL+GFS NV+
Sbjct  62   KEEMNEIELDDAPLCATSGYVFYNTSKWTLQTLFSTATNNQQILLANFEDYLNGFSENVK  121

Query  124  EILTKFKFRDQIQTLVDAHVLGYLIEDFLDPEINLSPLPVKDADGRIKLPALDNHGMGTV  183
            EI+  F+++ QI+ + + +VL  ++E F+ P INL+P +VK+     KLPAL N GMG V
Sbjct  122  EIVECFNLKAQIRHMAGKNVLLDVVEKFVSPYINLTP-AVKEDPEGNKLPALSNLGMGYV  180

Query  184  FEELIRRFNEENNEEAGEHFTPRDVVRLMAKLMFMPVADQIQSGTYLLYDGACGTGGMLT  243
            FEELIR+FNEENNEEAGEHFTPR+V+ LM+ L+F P+ D++  +   +YD ACG+GGMLT
Sbjct  181  FEELIRKFNEENNEEAGEHFTPREVIELMTHLVFDPIKDNLPLSI-TVYDPACGSGGMLT  239

Query  244  VAEETLRELAEEQGKEVSIHLFGQEINPETYAICKADLLLKGEGDEAEHIVGGADKSTLS  303
             +++ + E      ++  I L+G+EIN ETYAICK+D+++KG+  E  ++      STLS
Sbjct  240  ETQNFVEEKYPASNRD--IYLYGKEINDETYAICKSDMMIKGNNPENIRVG-----STLS  292

Query  304  NDQFRSREFDFMISNPPYGKSWKTDLDRMGGKKGFNDPRFIVSH----SGDPEFKLITRS  359
             D+F S  FDFM+SNPPYGKSW ++  ++   K   D RF V      + ++E   I RS
Sbjct  293  TDEFSSNRFDFMLSNPPYGKSWASEQKHIKEGKEVVDGRFKVKLKDYWGVESEQEAIPRS  352

Query  360  SDGQLMFLVNKLQKMK--QHSPLGSRIAIVHNGSALFTGDAGQGESNIRRWILENDWCEA  417
            SDGQL+FL++ + KMK  Q+SPLGSRIA VHNGS+LFTGDAG GESNIRR I+END  +A
Sbjct  353  SDGQLLFLMEMVTKMKSPQDSPLGSRIASVHNGSSLFTGDAGSGESNIRRYIIENDMLDA  412

Query  418  IIALPLNIFYNTGIATYIWVLTNRKAKHRKGRVQLIDATRWFQPLRRNLGKKNCELSEAD  477
            I+ LP N+FYNTGI+TYIW+L N K+ +R+G+VQLIDA+  F+ LR+NLG+KNCE+S  +
Sbjct  413  IVQLPNNLFYNTGITTYIWLLNNNKPENRQGKVQLIDASLLFRKLRKNLGNKNCEFSPEH  472

Query  478  IQRILDLYL------------GQPQNTPECKWFDNADFGYWKITVERPLRLKSQLTRRAI  525
            I  I+  YL            G+P   +  + F N DFGY K+ +ERP R ++Q+    I
Sbjct  473  IAEIVSTYLENQSVERAIDEKGDPVGIAA-QVFKNQDFGYYKVNIERPDRRNAQFRADLI  531

Query  526  ETLRFASGDEALRAEIWAKYGDKLY-AEFSK-LKPEIEAWLKgdtgedddepegdedegA  583
            E LRF +++  +   + A YG+++Y A F K +  EI  W                    
Sbjct  532  EPLRFENSQREVMEYLYAEYGEQVYDAGFVKGIEKEITKW------------------CE  573

Query  584  PAKKAVPEKRRKKLLDVSTWQRDKTLIelallaqqelGDGVFDDHNDFRARFEAAMAKHG  643
                ++    + KLLD   W +++TL++ A   ++ +GD V++D N+F+   +A ++  G
Sbjct  574  ENDISLNKAAKTKLLDTKNWMKQRTLVNAASQLHKKIGDEVYNDFNQFKQLVDAELTSLG  633

Query  644  KKLAAAEKKAIFKAVSWRDETAPPVIAKRTKLKKD------EPFEPGLDGV----YLEVA  693
             KL+A+EKKAI+ AVSW DE A  VI K +KLK+D      E +E  L+++    Y   +
Sbjct  634  LKLSAPEKKAILDAVSWYDENAEKVIKKVAKLKQDKLDDLLENYECELEDLPDFGYYPTG  693

Query  694  GKDRFLVEYEPDADLRDTEQVPLKEPGGIDAFFRREVLPHAPDAWIARDKTQIGYEISFA  753
              + F V YE+ +DLRD+E VPL +  +I  +F  EV PH  +AW+  +  +IGYEISF 
Sbjct  694  NHNEF-VTYESSSDLRDSESVPLEQ--SIYQYFLDEVKPHVDEAWVNLESVKIGYEISFN  750

Query  754  RYFYKPAPLRTLDEIRADILRLEQQTEGLLQKIVG  788
            +YFY+  PLR++DE+  +I+ LEQ++EGL+  I+G
Sbjct  751  KYFYRHKPLRSMDEVAKEIIALEQKAEGLIADILG  785

62) PA2735 in NC_002516


> EU272902|18|G17|167832524|ACA01834.1|Vibrio_cholerae_Amazonia_3509|-|21794..24175|-|VPI2_0017c|DNA 
methylase HsdM
Length=793

 Score =  526 bits (1983),  Expect = 2e-150, Method: Compositional matrix adjust.
 Identities = 364/816 (45%), Positives = 546/816 (67%), Gaps = 60/816 (7%)

Query  7    DQSQIKWVADFIWNIADDRLRDVYVRGKYRDVILPFTVLRRIDAVLEPTKQAVLERKKLL  66
            D+S  + +  FIW+IADD LRDVYVRGKYRDVILP  VLRR+D++LEP+K+AVLE  ++ 
Sbjct  2    DHSVHNKLVSFIWSIADDCLRDVYVRGKYRDVILPMVVLRRLDTLLEPSKEAVLEEVRFQ  61

Query  67   --DSAKVanqngalqaaagqaFYNVSEFTLAKL--KASAAGQRLREDFIAYLDGFSPNVQ  122
              +   +  ++++L A++G  FYN S  TL  L   A+   Q L  +F  YL+GFS NV+
Sbjct  62   KEEMNEIELDDAPLCATSGYVFYNTSKWTLQTLFSTATNNQQILLANFEDYLNGFSENVK  121

Query  123  EVLTKFNFRNQIQKLVDAHILGYLIEDFLDPEVNLSPLPVKDADGRTKLPALDNHGMGTV  182
            E++  FN++ QI+ + + ++L  ++E F+ P +NL+P +VK+     KLPAL N GMG V
Sbjct  122  EIVECFNLKAQIRHMAGKNVLLDVVEKFVSPYINLTP-AVKEDPEGNKLPALSNLGMGYV  180

Query  183  FEELIRRFNEENNEEAGEHFTPRDVVQLMAKLLFLPVADRIESSTYSLYDGSCGTGGMLT  242
            FEELIR+FNEENNEEAGEHFTPR+V++LM+ L+F P+ D +  S  ++YD +CG+GGMLT
Sbjct  181  FEELIRKFNEENNEEAGEHFTPREVIELMTHLVFDPIKDNLPLSI-TVYDPACGSGGMLT  239

Query  243  VAEEALKELAEQHGKDVSIHLFGQEISDETYAICKADLLLKGEGAEAENIVGGADKSTLS  302
             +++ + E      +D  I L+G+EI+DETYAICK+D+++KG+ +E   +      STLS
Sbjct  240  ETQNFVEEKYPASNRD--IYLYGKEINDETYAICKSDMMIKGNNPENIRVG-----STLS  292

Query  303  ADQFRSREFDFMISNPPYGKSWKTDLERMGGKKEFSDPRFIVNH----GGDAEFKLITRS  358
            +D+F S  FDFM+SNPPYGKSW ++  ++   KE  D RF V+     G ++E   I RS
Sbjct  293  TDEFSSNRFDFMLSNPPYGKSWASEQKHIKEGKEVVDGRFKVKLKDYWGVESEQEAIPRS  352

Query  359  SDGQLMFQVNKLSKMK--HDTALGSRIALVHNGSALFTGDAGQGESNIRRWVLENDWLEA  416
            SDGQL+F ++ ++KMK  +D++LGSRIA VHNGS+LFTGDAG GESNIRR ++END L+A
Sbjct  353  SDGQLLFLMEMVTKMKSPQDSPLGSRIASVHNGSSLFTGDAGSGESNIRRYIIENDMLDA  412

Query  417  IIALPLNIFYNTGIATYIWVLANKKAEHRKGRVQLIDASQWFAPLRRNLGKKNCELAEGD  476
            I+ LP N+FYNTGI+TYIW+L N+K+E+R+G+VQLIDAS  F  LR+NLG+KNCE++  +
Sbjct  413  IVQLPNNLFYNTGITTYIWLLNNNKPENRQGKVQLIDASLLFRKLRKNLGNKNCEFSPEH  472

Query  477  IRRILDLYLGEAQETDSSTDQ--------SKWFDTQDFGYWKITVERPLRLKSQLKTSAI  528
            I  I+  YL E Q  + + D+        ++ F  QDFGY K+ +ERP R ++Q+++  I
Sbjct  473  IAEIVSTYL-ENQSVERAIDEKGDPVGIAAQVFKNQDFGYYKVNIERPDRRNAQFRADLI  531

Query  529  DTLRFASGDEELRTEIYAEHGDKLY-TSFAK-LKPEIEAWLKggseddddaedgdeegTH  586
            + LRF +++ E+   +YAE G+++Y ++F K +  EI  W                   +
Sbjct  532  EPLRFENSQREVMEYLYAEYGEQVYDAGFVKGIEKEITKW-----------------CEE  574

Query  587  AKKAVPEKRRKRLLDATTWqrdkglldlallaqkvlgDAVFDDHNVFRAEFDIAMKAHDK  646
               ++    + +LLD+  W +++ L++ A   +K +GD V++D N F+   D  + + + 
Sbjct  575  NDISLNKAAKTKLLDTKNWMKQRTLVNAASQLHKKIGDEVYNDFNQFKQLVDAELTSLGL  634

Query  647  KLTAADKKAIFKAVSWRDDTAPPVVAKRHKLKAS--DAFIPSFDGR--------YFIETG  696
            KL+A++KKAI+ AVSW D+ A  V+ K  KLK    D ++ +++          Y+  TG
Sbjct  635  KLSAPEKKAILDAVSWYDENAEKVIKKVAKLKQDKLDDLLENYECELEDLPDFGYY-PTG  693

Query  697  KHREVVWYEPDADLRDTEQVPLKELGGIDAFFEREVLPHAPDAWIDGEKTQIGYEISFAR  756
            +H E V YE+ +DLRD+E VPL +  +I  +F  EV PH  +AW++ E  +IGYEISF +
Sbjct  694  NHNEFVTYESSSDLRDSESVPLEQ--SIYQYFLDEVKPHVDEAWVNLESVKIGYEISFNK  751

Query  757  YFYKPTPLRPLDDIRADILKLEQQTEGLLHKIVGTA  792
            YFY+  PLR++D++  +I+ LEQ++EGL+  I+G +
Sbjct  752  YFYRHKPLRSMDEVAKEIIALEQKAEGLIADILGIS  787

63) XFLM_04895 in NC_017562


> EU272902|18|G17|167832524|ACA01834.1|Vibrio_cholerae_Amazonia_3509|-|21794..24175|-|VPI2_0017c|DNA 
methylase HsdM
Length=793

 Score =  515 bits (1943),  Expect = 3e-147, Method: Compositional matrix adjust.
 Identities = 359/818 (44%), Positives = 532/818 (66%), Gaps = 67/818 (8%)

Query  7    DQSQIKWISDFIWNIADNRLRDVYVRGKYRDVILPFTVLRRLDAVLEATKDAVLERKKFL  66
            D+S  + +  FIW+IAD+ LRDVYVRGKYRDVILP  VLRRLD++LE++K+AVLE  +F 
Sbjct  2    DHSVHNKLVSFIWSIADDCLRDVYVRGKYRDVILPMVVLRRLDTLLEPSKEAVLEEVRFQ  61

Query  67   --DAHNVVEQDGALRMAAGQAFYNVSEFTLAKL--KASAAGQRLRDDFIAYLDGFSRDVQ  122
              + +++  +D++L  ++G  FYN S  TL  L   A+   Q L  +F  YL+GFS +V+
Sbjct  62   KEEMNEIELDDAPLCATSGYVFYNTSKWTLQTLFSTATNNQQILLANFEDYLNGFSENVK  121

Query  123  EILTKFNFRNQIQKLVDSHVLGYLIEDFLDPEVNLAPLPVKDADGRIKLPALDNHGMGTV  182
            EI+  FN++ QI+ + + +VL  ++E F+ P +NL+P +VK+     KLPAL N GMG V
Sbjct  122  EIVECFNLKAQIRHMAGKNVLLDVVEKFVSPYINLTP-AVKEDPEGNKLPALSNLGMGYV  180

Query  183  FEELIRRFNEDNNEEAGEHFTPRDVVQLMAKLLFLPVAERIESSTYSLYDGSCGTGGMLT  242
            FEELIR+FNE+NNEEAGEHFTPR+V++LM+ L+F P+ + +  S  ++YD +CG+GGMLT
Sbjct  181  FEELIRKFNEENNEEAGEHFTPREVIELMTHLVFDPIKDNLPLSI-TVYDPACGSGGMLT  239

Query  243  VaeealhalaeQHGKEVSIHLFGQEISDETYAICKADLLLKGEGAEAENIVGGADKSTLS  302
             +++ ++       ++  I L+G+EI+DETYAICK+D+++KG+ +E   +      STLS
Sbjct  240  ETQNFVEEKYPASNRD--IYLYGKEINDETYAICKSDMMIKGNNPENIRVG-----STLS  292

Query  303  ADQFPSRAFDFMISNPPYGKSWKTDLDRMGGKKGFSDRRFIVSH----GGDPEFKLLTRS  358
            +D+F+S  FDFM+SNPPYGKSW ++  ++   K   D RF V      G ++E   + RS
Sbjct  293  TDEFSSNRFDFMLSNPPYGKSWASEQKHIKEGKEVVDGRFKVKLKDYWGVESEQEAIPRS  352

Query  359  SDGQLMFQVNKLQKMK--HNTPLGSRIALVHNGSALFTGDAGQGESNIRRWVLENDWLEA  416
            SDGQL+F ++ + KMK  +++PLGSRIA VHNGS+LFTGDAG GESNIRR ++END L+A
Sbjct  353  SDGQLLFLMEMVTKMKSPQDSPLGSRIASVHNGSSLFTGDAGSGESNIRRYIIENDMLDA  412

Query  417  IIALPLNIFYNTGIATYIWVLANKKAQARRGKVQLIDASQWFQPLRRNLGKKNCELGAAD  476
            I+ LP N+FYNTGI+TYIW+L N+K++ R+GKVQLIDAS  F+ LR+NLG+KNCE+++ +
Sbjct  413  IVQLPNNLFYNTGITTYIWLLNNNKPENRQGKVQLIDASLLFRKLRKNLGNKNCEFSPEH  472

Query  477  IARILDLYLGQ-----------TQEAAQSKWFDTQDFGYWKVTIERPLRLKSQLSDERIE  525
            IA I+  YL +              +  ++ F  QDFGY KV IERP R ++Q+  + IE
Sbjct  473  IAEIVSTYLENQSVERAIDEKGDPVGIAAQVFKNQDFGYYKVNIERPDRRNAQFRADLIE  532

Query  526  SLRFATGEEALRAEIYATHGEALY-TEFAK-CKPAIEAWLKgedenedddsddsdsgddn  583
            +LRF  ++  +   +YA  GE +Y + F K     I  W                     
Sbjct  533  PLRFENSQREVMEYLYAEYGEQVYDAGFVKGIEKEITKW---------------------  571

Query  584  eapaarkavpvkrrkkLLDASTWQRDKALMEVAQRAQQALGRAVFDDHNAFCVGFDAVCK  643
                   ++    + KLLD+  W ++++L++ A + ++ +G  V++D N F    DA   
Sbjct  572  -CEENDISLNKAAKTKLLDTKNWMKQRTLVNAASQLHKKIGDEVYNDFNQFKQLVDAELT  630

Query  644  AQDARLSAPEKKAIYKAVSWRDDAALPVIAKRSKLKAG------ECFEPGFDG----AYL  693
            + + +LSAPEKKAI  AVSW D+ A  VI K +KLK +      E +E  +++    +Y 
Sbjct  631  SLGLKLSAPEKKAILDAVSWYDENAEKVIKKVAKLKQDKLDDLLENYECELEDLPDFGYY  690

Query  694  ETVGKDRFMVEYEPDSALRDTEQVPLQEPGGIDAFFAREVLPHAPDAWIATDKTQIGYEI  753
             T   + F V YE+ S LRD+E VPL++  +I  +F  EV PH  +AW+  +  +IGYEI
Sbjct  691  PTGNHNEF-VTYESSSDLRDSESVPLEQ--SIYQYFLDEVKPHVDEAWVNLESVKIGYEI  747

Query  754  SFARYFYKPVPLRTLADIRADILALEQQTEGLLHKIVG  791
            SF +YFY+  PLR++ ++  +I+ALEQ++EGL+  I+G
Sbjct  748  SFNKYFYRHKPLRSMDEVAKEIIALEQKAEGLIADILG  785

64) XfasM23_2177 in NC_010577


> EU272902|18|G17|167832524|ACA01834.1|Vibrio_cholerae_Amazonia_3509|-|21794..24175|-|VPI2_0017c|DNA 
methylase HsdM
Length=793

 Score =  515 bits (1943),  Expect = 3e-147, Method: Compositional matrix adjust.
 Identities = 359/818 (44%), Positives = 532/818 (66%), Gaps = 67/818 (8%)

Query  7    DQSQIKWISDFIWNIADNRLRDVYVRGKYRDVILPFTVLRRLDAVLEATKDAVLERKKFL  66
            D+S  + +  FIW+IAD+ LRDVYVRGKYRDVILP  VLRRLD++LE++K+AVLE  +F 
Sbjct  2    DHSVHNKLVSFIWSIADDCLRDVYVRGKYRDVILPMVVLRRLDTLLEPSKEAVLEEVRFQ  61

Query  67   --DAHNVVEQDGALRMAAGQAFYNVSEFTLAKL--KASAAGQRLRDDFIAYLDGFSRDVQ  122
              + +++  +D++L  ++G  FYN S  TL  L   A+   Q L  +F  YL+GFS +V+
Sbjct  62   KEEMNEIELDDAPLCATSGYVFYNTSKWTLQTLFSTATNNQQILLANFEDYLNGFSENVK  121

Query  123  EILTKFNFRNQIQKLVDSHVLGYLIEDFLDPEVNLAPLPVKDADGRIKLPALDNHGMGTV  182
            EI+  FN++ QI+ + + +VL  ++E F+ P +NL+P +VK+     KLPAL N GMG V
Sbjct  122  EIVECFNLKAQIRHMAGKNVLLDVVEKFVSPYINLTP-AVKEDPEGNKLPALSNLGMGYV  180

Query  183  FEELIRRFNEDNNEEAGEHFTPRDVVQLMAKLLFLPVAERIESSTYSLYDGSCGTGGMLT  242
            FEELIR+FNE+NNEEAGEHFTPR+V++LM+ L+F P+ + +  S  ++YD +CG+GGMLT
Sbjct  181  FEELIRKFNEENNEEAGEHFTPREVIELMTHLVFDPIKDNLPLSI-TVYDPACGSGGMLT  239

Query  243  VaeealhalaeQHGKEVSIHLFGQEISDETYAICKADLLLKGEGAEAENIVGGADKSTLS  302
             +++ ++       ++  I L+G+EI+DETYAICK+D+++KG+ +E   +      STLS
Sbjct  240  ETQNFVEEKYPASNRD--IYLYGKEINDETYAICKSDMMIKGNNPENIRVG-----STLS  292

Query  303  ADQFPSRAFDFMISNPPYGKSWKTDLDRMGGKKGFSDRRFIVSH----GGDPEFKLLTRS  358
            +D+F+S  FDFM+SNPPYGKSW ++  ++   K   D RF V      G ++E   + RS
Sbjct  293  TDEFSSNRFDFMLSNPPYGKSWASEQKHIKEGKEVVDGRFKVKLKDYWGVESEQEAIPRS  352

Query  359  SDGQLMFQVNKLQKMK--HNTPLGSRIALVHNGSALFTGDAGQGESNIRRWVLENDWLEA  416
            SDGQL+F ++ + KMK  +++PLGSRIA VHNGS+LFTGDAG GESNIRR ++END L+A
Sbjct  353  SDGQLLFLMEMVTKMKSPQDSPLGSRIASVHNGSSLFTGDAGSGESNIRRYIIENDMLDA  412

Query  417  IIALPLNIFYNTGIATYIWVLANKKAQARRGKVQLIDASQWFQPLRRNLGKKNCELGAAD  476
            I+ LP N+FYNTGI+TYIW+L N+K++ R+GKVQLIDAS  F+ LR+NLG+KNCE+++ +
Sbjct  413  IVQLPNNLFYNTGITTYIWLLNNNKPENRQGKVQLIDASLLFRKLRKNLGNKNCEFSPEH  472

Query  477  IARILDLYLGQ-----------TQEAAQSKWFDTQDFGYWKVTIERPLRLKSQLSDERIE  525
            IA I+  YL +              +  ++ F  QDFGY KV IERP R ++Q+  + IE
Sbjct  473  IAEIVSTYLENQSVERAIDEKGDPVGIAAQVFKNQDFGYYKVNIERPDRRNAQFRADLIE  532

Query  526  SLRFATGEEALRAEIYATHGEALY-TEFAK-CKPAIEAWLKgedenedddsddsdsgddn  583
            +LRF  ++  +   +YA  GE +Y + F K     I  W                     
Sbjct  533  PLRFENSQREVMEYLYAEYGEQVYDAGFVKGIEKEITKW---------------------  571

Query  584  eapaarkavpvkrrkkLLDASTWQRDKALMEVAQRAQQALGRAVFDDHNAFCVGFDAVCK  643
                   ++    + KLLD+  W ++++L++ A + ++ +G  V++D N F    DA   
Sbjct  572  -CEENDISLNKAAKTKLLDTKNWMKQRTLVNAASQLHKKIGDEVYNDFNQFKQLVDAELT  630

Query  644  AQDARLSAPEKKAIYKAVSWRDDAALPVIAKRSKLKAG------ECFEPGFDG----AYL  693
            + + +LSAPEKKAI  AVSW D+ A  VI K +KLK +      E +E  +++    +Y 
Sbjct  631  SLGLKLSAPEKKAILDAVSWYDENAEKVIKKVAKLKQDKLDDLLENYECELEDLPDFGYY  690

Query  694  ETVGKDRFMVEYEPDSALRDTEQVPLQEPGGIDAFFAREVLPHAPDAWIATDKTQIGYEI  753
             T   + F V YE+ S LRD+E VPL++  +I  +F  EV PH  +AW+  +  +IGYEI
Sbjct  691  PTGNHNEF-VTYESSSDLRDSESVPLEQ--SIYQYFLDEVKPHVDEAWVNLESVKIGYEI  747

Query  754  SFARYFYKPVPLRTLADIRADILALEQQTEGLLHKIVG  791
            SF +YFY+  PLR++ ++  +I+ALEQ++EGL+  I+G
Sbjct  748  SFNKYFYRHKPLRSMDEVAKEIIALEQKAEGLIADILG  785

65) hsdM in NC_004556


> EU272902|18|G17|167832524|ACA01834.1|Vibrio_cholerae_Amazonia_3509|-|21794..24175|-|VPI2_0017c|DNA 
methylase HsdM
Length=793

 Score =  515 bits (1943),  Expect = 3e-147, Method: Compositional matrix adjust.
 Identities = 359/818 (44%), Positives = 532/818 (66%), Gaps = 67/818 (8%)

Query  7    DQSQIKWISDFIWNIADNRLRDVYVRGKYRDVILPFTVLRRLDAVLEATKDAVLERKKFL  66
            D+S  + +  FIW+IAD+ LRDVYVRGKYRDVILP  VLRRLD++LE++K+AVLE  +F 
Sbjct  2    DHSVHNKLVSFIWSIADDCLRDVYVRGKYRDVILPMVVLRRLDTLLEPSKEAVLEEVRFQ  61

Query  67   --DAHNVVEQDGALRMAAGQAFYNVSEFTLAKL--KASAAGQRLRDDFIAYLDGFSRDVQ  122
              + +++  +D++L  ++G  FYN S  TL  L   A+   Q L  +F  YL+GFS +V+
Sbjct  62   KEEMNEIELDDAPLCATSGYVFYNTSKWTLQTLFSTATNNQQILLANFEDYLNGFSENVK  121

Query  123  EILTKFNFRNQIQKLVDSHVLGYLIEDFLDPEVNLAPLPVKDADGRIKLPALDNHGMGTV  182
            EI+  FN++ QI+ + + +VL  ++E F+ P +NL+P +VK+     KLPAL N GMG V
Sbjct  122  EIVECFNLKAQIRHMAGKNVLLDVVEKFVSPYINLTP-AVKEDPEGNKLPALSNLGMGYV  180

Query  183  FEELIRRFNEDNNEEAGEHFTPRDVVQLMAKLLFLPVAERIESSTYSLYDGSCGTGGMLT  242
            FEELIR+FNE+NNEEAGEHFTPR+V++LM+ L+F P+ + +  S  ++YD +CG+GGMLT
Sbjct  181  FEELIRKFNEENNEEAGEHFTPREVIELMTHLVFDPIKDNLPLSI-TVYDPACGSGGMLT  239

Query  243  VaeealhalaeQHGKEVSIHLFGQEISDETYAICKADLLLKGEGAEAENIVGGADKSTLS  302
             +++ ++       ++  I L+G+EI+DETYAICK+D+++KG+ +E   +      STLS
Sbjct  240  ETQNFVEEKYPASNRD--IYLYGKEINDETYAICKSDMMIKGNNPENIRVG-----STLS  292

Query  303  ADQFPSRAFDFMISNPPYGKSWKTDLDRMGGKKGFSDRRFIVSH----GGDPEFKLLTRS  358
            +D+F+S  FDFM+SNPPYGKSW ++  ++   K   D RF V      G ++E   + RS
Sbjct  293  TDEFSSNRFDFMLSNPPYGKSWASEQKHIKEGKEVVDGRFKVKLKDYWGVESEQEAIPRS  352

Query  359  SDGQLMFQVNKLQKMK--HNTPLGSRIALVHNGSALFTGDAGQGESNIRRWVLENDWLEA  416
            SDGQL+F ++ + KMK  +++PLGSRIA VHNGS+LFTGDAG GESNIRR ++END L+A
Sbjct  353  SDGQLLFLMEMVTKMKSPQDSPLGSRIASVHNGSSLFTGDAGSGESNIRRYIIENDMLDA  412

Query  417  IIALPLNIFYNTGIATYIWVLANKKAQARRGKVQLIDASQWFQPLRRNLGKKNCELGAAD  476
            I+ LP N+FYNTGI+TYIW+L N+K++ R+GKVQLIDAS  F+ LR+NLG+KNCE+++ +
Sbjct  413  IVQLPNNLFYNTGITTYIWLLNNNKPENRQGKVQLIDASLLFRKLRKNLGNKNCEFSPEH  472

Query  477  IARILDLYLGQ-----------TQEAAQSKWFDTQDFGYWKVTIERPLRLKSQLSDERIE  525
            IA I+  YL +              +  ++ F  QDFGY KV IERP R ++Q+  + IE
Sbjct  473  IAEIVSTYLENQSVERAIDEKGDPVGIAAQVFKNQDFGYYKVNIERPDRRNAQFRADLIE  532

Query  526  SLRFATGEEALRAEIYATHGEALY-TEFAK-CKPAIEAWLKgedenedddsddsdsgddn  583
            +LRF  ++  +   +YA  GE +Y + F K     I  W                     
Sbjct  533  PLRFENSQREVMEYLYAEYGEQVYDAGFVKGIEKEITKW---------------------  571

Query  584  eapaarkavpvkrrkkLLDASTWQRDKALMEVAQRAQQALGRAVFDDHNAFCVGFDAVCK  643
                   ++    + KLLD+  W ++++L++ A + ++ +G  V++D N F    DA   
Sbjct  572  -CEENDISLNKAAKTKLLDTKNWMKQRTLVNAASQLHKKIGDEVYNDFNQFKQLVDAELT  630

Query  644  AQDARLSAPEKKAIYKAVSWRDDAALPVIAKRSKLKAG------ECFEPGFDG----AYL  693
            + + +LSAPEKKAI  AVSW D+ A  VI K +KLK +      E +E  +++    +Y 
Sbjct  631  SLGLKLSAPEKKAILDAVSWYDENAEKVIKKVAKLKQDKLDDLLENYECELEDLPDFGYY  690

Query  694  ETVGKDRFMVEYEPDSALRDTEQVPLQEPGGIDAFFAREVLPHAPDAWIATDKTQIGYEI  753
             T   + F V YE+ S LRD+E VPL++  +I  +F  EV PH  +AW+  +  +IGYEI
Sbjct  691  PTGNHNEF-VTYESSSDLRDSESVPLEQ--SIYQYFLDEVKPHVDEAWVNLESVKIGYEI  747

Query  754  SFARYFYKPVPLRTLADIRADILALEQQTEGLLHKIVG  791
            SF +YFY+  PLR++ ++  +I+ALEQ++EGL+  I+G
Sbjct  748  SFNKYFYRHKPLRSMDEVAKEIIALEQKAEGLIADILG  785

66) Xfasm12_2269 in NC_010513


> EU272902|18|G17|167832524|ACA01834.1|Vibrio_cholerae_Amazonia_3509|-|21794..24175|-|VPI2_0017c|DNA 
methylase HsdM
Length=793

 Score =  491 bits (1850),  Expect = 7e-140, Method: Compositional matrix adjust.
 Identities = 343/794 (44%), Positives = 513/794 (65%), Gaps = 67/794 (8%)

Query  1    MRGKYRDVILPFTVLRRLDAVLEATKDAVLERKKFL--DAHNVAEQDGALRMAAGQAFYN  58
            +RGKYRDVILP  VLRRLD++LE++K+AVLE  +F   + +++  +D++L  ++G  FYN
Sbjct  26   VRGKYRDVILPMVVLRRLDTLLEPSKEAVLEEVRFQKEEMNEIELDDAPLCATSGYVFYN  85

Query  59   VSEFTLAKL--KASAAGQRLRDDFIAYLDGFSRDVQEILTKFNFRNQIQKLVDSHVLGYL  116
             S  TL  L   A+   Q L  +F  YL+GFS +V+EI+  FN++ QI+ + + +VL  +
Sbjct  86   TSKWTLQTLFSTATNNQQILLANFEDYLNGFSENVKEIVECFNLKAQIRHMAGKNVLLDV  145

Query  117  IEDFLNPEVNLAPLPVKDADGRIKLPALDNHGMGTVFEELIRRFNEDNNEEAGEHFTPRD  176
            +E F++P +NL+P +VK+     KLPAL N GMG VFEELIR+FNE+NNEEAGEHFTPR+
Sbjct  146  VEKFVSPYINLTP-AVKEDPEGNKLPALSNLGMGYVFEELIRKFNEENNEEAGEHFTPRE  204

Query  177  VVQLMAKLLFLPVAERIESSTYSLYDGSCGTGGMLTVaeealhalaeQHGKEVSIHLFGQ  236
            V++LM+ L+F P+ + +  S  ++YD +CG+GGMLT +++ ++       ++  I L+G+
Sbjct  205  VIELMTHLVFDPIKDNLPLSI-TVYDPACGSGGMLTETQNFVEEKYPASNRD--IYLYGK  261

Query  237  EISDETYAICKADLLLKGEGAEAQNIVGGADKSTLSADQFHSRAFDFMISNPPYGKSWKT  296
            EI+DETYAICK+D+++KG+ +E   +      STLS+D+F S  FDFM+SNPPYGKSW +
Sbjct  262  EINDETYAICKSDMMIKGNNPENIRVG-----STLSTDEFSSNRFDFMLSNPPYGKSWAS  316

Query  297  DLERMGGKKGFSDPRFIVSH----GGDSEFKLLTRSSDGQLMFQVNKLQKMK--HNTPLG  350
            +  ++   K   D RF V      G +SE   + RSSDGQL+F ++ + KMK  +++PLG
Sbjct  317  EQKHIKEGKEVVDGRFKVKLKDYWGVESEQEAIPRSSDGQLLFLMEMVTKMKSPQDSPLG  376

Query  351  SRIALVHNGSALFTGDAGQGESNIRRWVLENDWLEAIIALPLNIFYNTGIATYIWVLANK  410
            SRIA VHNGS+LFTGDAG GESNIRR ++END L+AI+ LP N+FYNTGI+TYIW+L N+
Sbjct  377  SRIASVHNGSSLFTGDAGSGESNIRRYIIENDMLDAIVQLPNNLFYNTGITTYIWLLNNN  436

Query  411  KAEARRGKVQLIDASQWFQPLRRNLGKKNCELGAADIARILDLYLGQ-----------AQ  459
            K+E R+GKVQLIDAS  F+ LR+NLG+KNCE+++ +IA I+  YL +             
Sbjct  437  KPENRQGKVQLIDASLLFRKLRKNLGNKNCEFSPEHIAEIVSTYLENQSVERAIDEKGDP  496

Query  460  EAAQSKWFDTQDFGYWKITIERPLRLKSQLSDERIESLRFATGDEALRAEIYATHGEALY  519
             +  ++ F  QDFGY K+ IERP R ++Q+  + IE+LRF  ++  +   +YA  GE +Y
Sbjct  497  VGIAAQVFKNQDFGYYKVNIERPDRRNAQFRADLIEPLRFENSQREVMEYLYAEYGEQVY  556

Query  520  -TEFAK-RKPAIEAWLKgedenedddnedsdsgddneapaarkavpvkrrkkLLDASTWQ  577
             + F K     I  W                            ++    + KLLD+  W 
Sbjct  557  DAGFVKGIEKEITKW----------------------CEENDISLNKAAKTKLLDTKNWM  594

Query  578  RDKALMEVAQRAQQTLGHAVFDDHNAFCACFDAVCKAQDARLSAPEKKVIYKAVSWRDDA  637
            ++++L++ A + ++ +G+ V++D N F    DA   + + +LSAPEKK I  AVSW D+ 
Sbjct  595  KQRTLVNAASQLHKKIGDEVYNDFNQFKQLVDAELTSLGLKLSAPEKKAILDAVSWYDEN  654

Query  638  ALPVIAKRSKLKAG------DYFEPGFDG----AYLETVGKDRFMVEYEPDSALRDTEQV  687
            A  VI K +KLK +      + +E  +++    +Y  T   + F V YE+ S LRD+E V
Sbjct  655  AEKVIKKVAKLKQDKLDDLLENYECELEDLPDFGYYPTGNHNEF-VTYESSSDLRDSESV  713

Query  688  PLKEPGGIDAFFSREVLPHAPDAWIATNKTQVGYEISFSRYFYKPVPLRTLAEIRADILV  747
            PL +  +I  +F  EV PH  +AW+  +  ++GYEISF++YFY+  PLR++ E+  +I+ 
Sbjct  714  PLEQ--SIYQYFLDEVKPHVDEAWVNLESVKIGYEISFNKYFYRHKPLRSMDEVAKEIIA  771

Query  748  LEQQTEGLLHKIVG  761
            LEQ++EGL+  I+G
Sbjct  772  LEQKAEGLIADILG  785

67) Metho_0633 in NC_019977


> EU272902|18|G17|167832524|ACA01834.1|Vibrio_cholerae_Amazonia_3509|-|21794..24175|-|VPI2_0017c|DNA 
methylase HsdM
Length=793

 Score =  474 bits (1785),  Expect = 9e-135, Method: Compositional matrix adjust.
 Identities = 340/798 (43%), Positives = 511/798 (65%), Gaps = 102/798 (12%)

Query  1    MSDNSVNWIANFIWGIADDVLRDLYVRGKYRDVVLPMTVLRRLDAVLEPTKQNVLD----  56
            M ++  N + +FIW+IADD LRD+YVRGKYRDV+LPM VLRRLD++LEP+K+ VL+    
Sbjct  1    MDHSVHNKLVSFIWSIADDCLRDVYVRGKYRDVILPMVVLRRLDTLLEPSKEAVLEEVRF  60

Query  57   MKSTLDNAGITNQDQALRQAAGQAFYNTSQFTLRDL--RSRASQQQLKADFEAYLDGFSP  114
             K  +++  +  +D +L  ++G  FYNTS+ TL+ L   +  +QQ L A+FE YL+GFS 
Sbjct  61   QKEEMNEIEL--DDAPLCATSGYVFYNTSKWTLQTLFSTATNNQQILLANFEDYLNGFSE  118

Query  115  NVQEILDNFEFRNQIPRLSKADALGKLIEKFLDPSINLSPNPVLNGDGSVKHPGPDNHAM  174
            NV+EI++ F+++ QI +++  + L  ++EKF+ P INL+P    + +G+ K P+  N +M
Sbjct  119  NVKEIVECFNLKAQIRHMAGKNVLLDVVEKFVSPYINLTPAVKEDPEGN-KLPALSNLGM  177

Query  175  GTIFEELVRRFNEENNEEAGEHWTPRDAVKLMANLIFLPIADDIESGTYLLYDGACGTGG  234
            G +FEEL+R+FNEENNEEAGEH TPR+ + LM++L+F PI D++  +   +YD ACG+GG
Sbjct  178  GYVFEELIRKFNEENNEEAGEHFTPREVIELMTHLVFDPIKDNLPLSI-TVYDPACGSGG  236

Query  235  MLTVAEETLLQLSQEHGKQVATHLYGQEINAETYAIAKADFLLKGEGDAADNLVGGPEHS  294
            MLT +++ + +      +++   LYG+EIN ETYAI K+D ++KG  + ++N+  G   S
Sbjct  237  MLTETQNFVEEKYPASNRDI--YLYGKEINDETYAICKSDMMIKG--NNPENIRVG---S  289

Query  295  TLANDAFPAREFDFMLSNPPYGKSWKSDLERMGGKDGIKDPRFVIEH----AGDPEYSLL  350
            TL+ D F++  FDFMLSNPPYGKSW S+  ++     + D RF +      + ++E   +
Sbjct  290  TLSTDEFSSNRFDFMLSNPPYGKSWASEQKHIKEGKEVVDGRFKVKLKDYWGVESEQEAI  349

Query  351  TRSSDGQMLFLANMLSKMK--RNTKLGSRIAEVHNGSSLFTGDAGQGESNIRRWIIENDW  408
             RSSDGQ+LFL +M++KMK  +++ LGSRIA VHNGSSLFTGDAG GESNIRR IIEND 
Sbjct  350  PRSSDGQLLFLMEMVTKMKSPQDSPLGSRIASVHNGSSLFTGDAGSGESNIRRYIIENDM  409

Query  409  LEAIVALPLNMFYNTGIATYIWVLGNRKPEHRRGKVQLIDATQWYKPLRKNLGKKNCELS  468
            L+AIV LP N+FYNTGI+TYIW+L N KPE+R+GKVQLIDA+  ++ LRKNLG+KNCE+S
Sbjct  410  LDAIVQLPNNLFYNTGITTYIWLLNNNKPENRQGKVQLIDASLLFRKLRKNLGNKNCEFS  469

Query  469  DEDIKKICDTFLAFEESEQS------------KIFPNAAFGYWKVTVER-----------  505
             E+I  I  T+L  +  E++            ++F N  FGY KV +ER           
Sbjct  470  PEHIAEIVSTYLENQSVERAIDEKGDPVGIAAQVFKNQDFGYYKVNIERPDRRNAQFRAD  529

Query  506  ---PLR-----------LTVDLGEKSREV-FRKS--------CGTGEEQLA---------  533
               PLR           L  + GE+  +  F K+        C   +  L          
Sbjct  530  LIEPLRFENSQREVMEYLYAEYGEQVYDAGFVKGIEKEITKWCEENDISLNKAAKTKLLD  589

Query  534  --------GLIDKAAE---KLGSGSHNDFNVFISALEAMASGFGVKLTAKRQKLVQNSLA  582
                     L++ A++   K+G    NDFN F   ++A  +++G+KL+A  +K + ++++
Sbjct  590  TKNWMKQRTLVNAASQLHKKIGDEVYNDFNQFKQLVDAELTSLGLKLSAPEKKAILDAVS  649

Query  583  QRDESAERVVSKVHRLGKTEADPLKGLFEATVN----------GKHV-VVEYEPDSELRD  631
              DE+AE+V+ KV +L +   D L   +E  ++          G+H   V YE+ S+LRD
Sbjct  650  WYDENAEKVIKKVAKLKQDKLDDLLENYECELEDLPDFGYYPTGNHNEFVTYESSSDLRD  709

Query  632  TEQIPLMEEGGIESFIRREVLPHAADAWIDESSVKVGYEVSFTRYFYKPQPMRSLEEIRA  691
            +E +PL  E +I  ++  EV PH  +AW++  SVK+GYE+SF +YFY+ +P+RS++E+  
Sbjct  710  SESVPL--EQSIYQYFLDEVKPHVDEAWVNLESVKIGYEISFNKYFYRHKPLRSMDEVAK  767

Query  692  DILALEKETDGLLAEIIG  709
            +I+ALE+ ++GL+A+I+G
Sbjct  768  EIIALEQKAEGLIADILG  785

68) GM18_2924 in NC_014973


> EU272902|18|G17|167832524|ACA01834.1|Vibrio_cholerae_Amazonia_3509|-|21794..24175|-|VPI2_0017c|DNA 
methylase HsdM
Length=793

 Score =  424 bits (1595),  Expect = 1e-119, Method: Compositional matrix adjust.
 Identities = 288/607 (48%), Positives = 419/607 (70%), Gaps = 47/607 (7%)

Query  1    MNHVIHNSIVNFIWGIADDVLRDVYVRGKYRDVILPMTVIRRLDALLEPSKEKVLG---M  57
            M+H +HN +V+FIW+IADD LRDVYVRGKYRDVILPM V+RRLD+LLEPSKE VL     
Sbjct  1    MDHSVHNKLVSFIWSIADDCLRDVYVRGKYRDVILPMVVLRRLDTLLEPSKEAVLEEVRF  60

Query  58   KKQLDGAGIANQHAALCQAAGEAFYNVSPFTLRDL--KNRAKQQQLKADFEAYLDGFSPN  115
            +K+ +   I  ++A+LC ++G  FYN S  TL+ L      +QQ L A+FE YL+GFS N
Sbjct  61   QKE-EMNEIELDDAPLCATSGYVFYNTSKWTLQTLFSTATNNQQILLANFEDYLNGFSEN  119

Query  116  VQEILDKFKFRNQIPTLIEADILGHLIEKFLDGRVNLSPKPVQDVDGNEILPALDNHSMG  175
            V+EI++ F+++ QI  +   ++L +++EKF+   +NL+P   +D +GN  LPAL N +MG
Sbjct  120  VKEIVECFNLKAQIRHMAGKNVLLDVVEKFVSPYINLTPAVKEDPEGNK-LPALSNLGMG  178

Query  176  TIFEELIRRFNEENNEEAGEHFTPRDVVKLMADLIFLPVADDIESGTYLVYDGACGTGGM  235
             +FEELIR+FNEENNEEAGEHFTPR+V+ LM++L+F P+ D++  +   VYD ACG+GGM
Sbjct  179  YVFEELIRKFNEENNEEAGEHFTPREVIELMTHLVFDPIKDNLPLSI-TVYDPACGSGGM  237

Query  236  LTVAEERLAELAESHGKDVSIHLFGQEVQPETYAISKADLLLKGEGAEAENMKYGSTLSS  295
            LT +++ + E   +  +D  I L+G+E++ ETYAI K+D+++KG+  ++EN++ GSTLS+
Sbjct  238  LTETQNFVEEKYPASNRD--IYLYGKEINDETYAICKSDMMIKGN--NPENIRVGSTLST  293

Query  296  DAFPSQEFDFMLSNPPYGKSWKTDLERLGGKGDIKDPRFVTQH----GGDPEYKMITRSS  351
            D F+S+ FDFMLSNPPYGKSW ++  ++    ++ D RF  +     G ++E   I RSS
Sbjct  294  DEFSSNRFDFMLSNPPYGKSWASEQKHIKEGKEVVDGRFKVKLKDYWGVESEQEAIPRSS  353

Query  352  DGQLMFLVNKLSKMK--HTTRLGSRIAEVHNGSSLFTGDAGQGESNIRRWIIENDWLEAI  409
            DGQL+FL++ ++KMK  + + LGSRIA VHNGSSLFTGDAG GESNIRR IIEND L+AI
Sbjct  354  DGQLLFLMEMVTKMKSPQDSPLGSRIASVHNGSSLFTGDAGSGESNIRRYIIENDMLDAI  413

Query  410  IALPENMFYNTGIATYIWVLTNRKSDTRRGKVQLIDATEWYVPLRRNLGKKNCEFSEEHI  469
            + LP+N+FYNTGI+TYIW+L N K++ R+GKVQLIDA+  +  LR+NLG+KNCEFS EHI
Sbjct  414  VQLPNNLFYNTGITTYIWLLNNNKPENRQGKVQLIDASLLFRKLRKNLGNKNCEFSPEHI  473

Query  470  RAICDLVVNPVETDK------------SKIFPNEAFGYWKVTVDRPLRLAVDLSPARLE-  516
              I    ++    ++            +++F N+ FGY KV ++RP R   ++ +  +E 
Sbjct  474  AEIVSTYLENQSVERAIDEKGDPVGIAAQVFKNQDFGYYKVNIERPDRRNAQFRADLIEP  533

Query  517  -RFERACAKAKEEPLANLASRVAEALGVGPHLDFNAFMNAVEADADK----HGVKLT-AK  570
             RFE +     E   A+ + +V +A          +F++++E +  K    +++ L  A 
Sbjct  534  LRFENSQREVMEYLYAEYGEQVYDA----------GFVKGIEKEITKWCEENDISLNKAA  583

Query  571  RKKLLQS  577
            + KLL++
Sbjct  584  KTKLLDT  590


 Score = 90.7 bits (325),  Expect = 2e-19, Method: Compositional matrix adjust.
 Identities = 68/196 (35%), Positives = 107/196 (55%), Gaps = 19/196 (9%)

Query  526  KEEPLANLASRVAEALGVGPHLDFNAFMNAVEADADKHGVKLTAKRKKLLQSDLCDTRED  585
            K+  L N AS++   +G     DFN F + V+A+    G+KL+A  KK +   +    E+
Sbjct  595  KQRTLVNAASQLHKKIGDEVYNDFNQFKQLVDAELTSLGLKLSAPEKKAILDAVSWYDEN  654

Query  586  AAPVLKKVHKPGKATPDPIHGLVEA--------------EVNGKTCVVEYEPDTALRDTE  631
            A  V+KKV   +K   D +++L+E                       V YE+ + LRD+E
Sbjct  655  AEKVIKKV---AKLKQDKLDDLLENYECELEDLPDFGYYPTGNHNEFVTYESSSDLRDSE  711

Query  632  QVPLLEEGGIEAFIRREVLPYTPDAWIDPDKTLVGYEISFTRHFYRPAPMRTLDEIKADI  691
             VPL  E +I  ++  EV P   +AW++ +   +GYEISF + FYR  P+R++DE+  +I
Sbjct  712  SVPL--EQSIYQYFLDEVKPHVDEAWVNLESVKIGYEISFNKYFYRHKPLRSMDEVAKEI  769

Query  692  YALEQETEGLLEQIVG  707
             ALEQ +EGL+ +I+G
Sbjct  770  IALEQKAEGLIADILG  785

69) Tery_4473 in NC_008312


> EU272902|18|G17|167832524|ACA01834.1|Vibrio_cholerae_Amazonia_3509|-|21794..24175|-|VPI2_0017c|DNA 
methylase HsdM
Length=793

 Score =  421 bits (1586),  Expect = 5e-119, Method: Compositional matrix adjust.
 Identities = 285/564 (51%), Positives = 402/564 (72%), Gaps = 36/564 (6%)

Query  1    MDQNIHNGIVSFIWGIADDVLRDIYVRGKYRDVILPMTVIRRLDCLLEPTKAAVLKENNF  60
            MD+++HN +VSFIW+IADD LRD+YVRGKYRDVILPM V+RRLD LLEP+K AVL E  F
Sbjct  1    MDHSVHNKLVSFIWSIADDCLRDVYVRGKYRDVILPMVVLRRLDTLLEPSKEAVLEEVRF  60

Query  61   YENMEIS----DKSGLTEFTKYPFYNTSGFTLKKLLDEPRSIKENLI----DYLNGFSDN  112
             ++ E++    D + L   + Y FYNTS  TL+ L+  + + ++ L+    DYLNGFS+N
Sbjct  61   -QKEEMNEIELDDAPLCATSGYVFYNTSKWTLQTLFSTATNNQQILLANFEDYLNGFSEN  119

Query  113  VQEIINKFKFRNQLETLVEHKRLYALIQKFTDSDINLSPEPRKDKKGKVIQPGLSNLGMG  172
            V+EI++ F+++ Q+  +   + L  +++KF  + INL+P  + D  G+ + P+LSNLGMG
Sbjct  120  VKEIVECFNLKAQIRHMAGKNVLLDVVEKFVSPYINLTPAVKEDPEGNKL-PALSNLGMG  178

Query  173  YVFEELIRKFNEENNEEAGEHFTPRDIIKLMVNLIFMPVKDQIKNTTYLVYDCACGSGGM  232
            YVFEELIRKFNEENNEEAGEHFTPR++I LM +L+F P+KD++  +   VYD ACGSGGM
Sbjct  179  YVFEELIRKFNEENNEEAGEHFTPREVIELMTHLVFDPIKDNLPLSI-TVYDPACGSGGM  237

Query  233  LTEAENFLLELATGMGKKVVIHLFGQEVNPETYAICQADMLIKVKETDNIKYASTLASDG  292
            LTE++NF+ E   +  +   I L+G+E+N ETYAIC++DM+IK ++ +NI+ +STL++D 
Sbjct  238  LTETQNFVEEKYPASNRD--IYLYGKEINDETYAICKSDMMIKGNNPENIRVGSTLSTDE  295

Query  293  FPDFTFDFMLANPPYGKSWKVDQDKILVGRKKEVKDNRFLVKHQG-----EELQLIPRSS  347
            F+   FDFML+NPPYGKSW  +Q  I  G  KEV D RF VK ++      E + IPRSS
Sbjct  296  FSSNRFDFMLSNPPYGKSWASEQKHIKEG--KEVVDGRFKVKLKDYWGVESEQEAIPRSS  353

Query  348  DGQLLFLVNKLSKMKDS--TKLGSRIAIVHNGSALFTGDAGSGESNIRRWIIENDWLECI  405
            DGQLLFL++ ++KMK +  + LGSRIA VHNGS+LFTGDAGSGESNIRR IIEND L+ I
Sbjct  354  DGQLLFLMEMVTKMKSPQDSPLGSRIASVHNGSSLFTGDAGSGESNIRRYIIENDMLDAI  413

Query  406  VGLPLNMFYNTGIATYIWIISNKKSVERRGKVQLIDGREWYGKLRKSLGSKSCELRGEDI  465
            V LP N+FYNTGI+TYIW+++N+K+ +R+GKVQLID+   + KLRK+LG+K+CE+  E+I
Sbjct  414  VQLPNNLFYNTGITTYIWLLNNNKPENRQGKVQLIDASLLFRKLRKNLGNKNCEFSPEHI  473

Query  466  DRITEEFLDFSESD------------NSRIFDNEDFGFHKIVVERPLRFSFQVTAARVQE  513
              I   +L+    +             +++F N+DFG+ K+ +ERP R + Q  A  ++ 
Sbjct  474  AEIVSTYLENQSVERAIDEKGDPVGIAAQVFKNQDFGYYKVNIERPDRRNAQFRADLIEP  533

Query  514  FGEKMGDDLLGVVDILRGLFGEEV  537
            +  +  +    V++ L + +GE+V
Sbjct  534  L--RFENSQREVMEYLYAEYGEQV  555


 Score = 72.1 bits (254),  Expect = 1e-13, Method: Compositional matrix adjust.
 Identities = 33/63 (53%), Positives = 49/63 (78%), Gaps = 0/63 (0%)

Query  590  VVYQADAELRDTENVPLKENIQEYFEREVLPHVSDAWIDFDKVVRGYEISFTKYFYKFQK  649
            V Y++ ++LRD+E+VPL ++I +YF  EV PHV +AW++++ V  GYEISF KYFY+ + 
Sbjct  699  VTYESSSDLRDSESVPLEQSIYQYFLDEVKPHVDEAWVNLESVKIGYEISFNKYFYRHKP  758

Query  650  LRS  652
            LRS
Sbjct  759  LRS  761

70) Dd1591_4253 in NC_012912


> EU272902|18|G17|167832524|ACA01834.1|Vibrio_cholerae_Amazonia_3509|-|21794..24175|-|VPI2_0017c|DNA 
methylase HsdM
Length=793

 Score =  329 bits (1233),  Expect = 4e-91, Method: Compositional matrix adjust.
 Identities = 244/563 (44%), Positives = 354/563 (63%), Gaps = 68/563 (12%)

Query  1    MNGETHRQLANFIWSI---CNLLRGPYKRNEYRKVILPLTVLRRFECLLEPTRQDALAEF  57
            M+   H +L +FIWSI   C  LR+ Y R  YR VILP+ VLRR++ LLEP+++  L E 
Sbjct  1    MDHSVHNKLVSFIWSIADDC--LRDVYVRGKYRDVILPMVVLRRLDTLLEPSKEAVLEEV  58

Query  58   QWLKTKPERVQ--QARLQQITGYRFYNLSR--MQLTLSGENIHSllddpnnlapnlnSYI  113
            +  K   + ++  +A L   +GY FYN S+  +Q  +S    +  +  +N        Y+
Sbjct  59   RFQKEEMNEIELDDAPLCATSGYVFYNTSKWTLQTLFSTATNNQQILLANFE-----DYL  113

Query  114  NGFSANVRAIMERFKFSEQITHMAEKNILFEVVKAFAK--IDLSP-----------QRVD  160
            NGFS NV+ I+E F++  QI HMA KN+L++VV  F    I+L+P             + 
Sbjct  114  NGFSENVKEIVECFNLKAQIRHMAGKNVLLDVVEKFVSPYINLTPAVKEDPEGNKLPALS  173

Query  161  QMQMGYVFEELIRIGAEQSNEEAGEHFTPREVIKLMVNLLLAP-EEDLAKSDVVKTIYDP  219
            ++ MGYVFEELIR   E++NEEAGEHFTPREVI LM +L++ P  ++L+   +  T+YDP
Sbjct  174  NLGMGYVFEELIRKFNEENNEEAGEHFTPREVIELMTHLVFDPIKDNLP---LSITVYDP  230

Query  220  ACGTGGMLSVAEEYI--RHLNSDARPHLYGQDWNDEAWAVCKSDMLIKGEDADNIILGDT  277
            ACG+GGML+ +++++  +   S+    LYG++ NDE+ A+CKSDM+IKG++++NI +G T
Sbjct  231  ACGSGGMLTETQNFVEEKYPASNRDIYLYGKEINDETYAICKSDMMIKGNNPENIRVGST  290

Query  278  FTRDGFDRDSDGNKWIFDYMLANPPFGVEWKQQQKYIQKEADELGYAGRF----------  327
            ++ D F  +       FD+ML+NPP+G  W  +QK I KE+ E+   GRF          
Sbjct  291  LSTDEFSSNR------FDFMLSNPPYGKSWASEQKHI-KEGKEVV-DGRFKVKLKDYWGV  342

Query  328  ---GAGTPRINDGALLFLQHMISKMRPVNKD--GSRIGIVFNGSPLFTGDAGSGESEIRR  382
                 + PR +DG LLFL +M++KM++ +    GSRI+ V NGS+LFTGDAGSGES+IRR
Sbjct  343  ESEQEAIPRSSDGQLLFLMEMVTKMKSPQDSPLGSRIASVHNGSSLFTGDAGSGESNIRR  402

Query  383  WIIENDWLEAIVALPEQLFYNTGIATYIWVITNRKAKERKGKVQLIDARNFWVPMEKSLG  442
             IIEND L+AIV LP++LFYNTGI+TYIW++ N K+ +R+GKVQLIDA  +   + K+LG
Sbjct  403  YIIENDMLDAIVQLPNNLFYNTGITTYIWLLNNNKPENRQGKVQLIDASLLFRKLRKNLG  462

Query  443  NKRRRIGDPQDRPKDPNHIAEITRIYENFQDGETRTFFLDGKEKEL-VVSKLFDNDDFGY  501
            NK   ++        P+HIAEI   Y + Q  E     +D K   + + +++F N+DFGY
Sbjct  463  NKNCEFS--------PEHIAEIVSTYLENQSVERA---IDEKGDPVGIAAQVFKNQDFGY  511

Query  502  HKITVERPLRLNFQATAERIARL  524
             K+ +ERP R N Q  A+ I  L
Sbjct  512  YKVNIERPDRRNAQFRADLIEPL  534


 Score = 68.7 bits (241),  Expect = 9e-13, Method: Compositional matrix adjust.
 Identities = 36/82 (44%), Positives = 54/82 (66%), Gaps = 0/82 (0%)

Query  625  EADTDLRDTETVPLKESIEEYFQREVLLHVPDAWIDYAKTKIGYEIPLNRHFYRYEEPRE  684
            E+ +DLRD+E+VPL +SI +YF  EV  HV +AW++    KIGYEI++N+ FYR    R 
Sbjct  702  ESSSDLRDSESVPLEQSIYQYFLDEVKPHVDEAWVNLESVKIGYEISFNKYFYRHKPLRS  761

Query  685  LTEIEAEIKGLESEILELLKEV  706
            + E+  EI +LE     L+ ++
Sbjct  762  MDEVAKEIIALEQKAEGLIADI  783

71) B932_2648 in NC_019396


> EU272902|18|G17|167832524|ACA01834.1|Vibrio_cholerae_Amazonia_3509|-|21794..24175|-|VPI2_0017c|DNA 
methylase HsdM
Length=793

 Score =  317 bits (1188),  Expect = 1e-87, Method: Compositional matrix adjust.
 Identities = 242/586 (42%), Positives = 366/586 (63%), Gaps = 60/586 (10%)

Query  1    MQREEIRNLSGFAWSVAE-ILRGDFKQSEYGKVILPFVVLRRLDCILETSKAQVLDAAKA  59
            M++    +L +F WS+A+  LR+ + ++ Y  VILP VVLRRLD +LE SK  VL+  + 
Sbjct  1    MDHSVHNKLVSFIWSIADDCLRDVYVRGKYRDVILPMVVLRRLDTLLEPSKEAVLEEVRF  60

Query  60   LPDGVDEATRDMILFGAVGGNVKVYNLSRFTFATL---KGQDPGQLHQNLVDYITNFSSN  116
              + ++E   D   + A +G V  YN S+ T+ TL     ++   L  N+ DY+  FS N
Sbjct  61   QKEEMNEIELDDAPLCATSGYV-FYNTSKWTLQTLFSTATNNQQILLANFEDYLNGFSEN  119

Query  117  VRDIFLDKFLFTDQIKRLKDGGILWNVFQRMTE--IDLHPN-----------RVTNIEMG  163
            V++I ++ F +  QI+++ +  +L +V ++     I+L P             ++N+ MG
Sbjct  120  VKEI-VECFNLKAQIRHMAGKNVLLDVVEKFVSPYINLTPAVKEDPEGNKLPALSNLGMG  178

Query  164  YLFEELIRRFSEISNETAGEHFTPREVIRLIVDLLIANDDTKLTKRGIIRQVYDPACGTG  223
            Y+FEELIR+F+E +NE AGEHFTPREVI L+ +L++     +L    +   VYDPACG+G
Sbjct  179  YVFEELIRKFNEENNEEAGEHFTPREVIELMTHLVFDPIKDNLP---LSITVYDPACGSG  235

Query  224  GMLALTEEALQD-FNPSIR-VELFGQEINAESFGICKSDMLVTGHDPEQIAFGNTLTQDA  281
            GML+ T++ +++ + +S R + L+G+EIN E+++ICKSDM++ G++PE+I  G+TL+ D 
Sbjct  236  GMLTETQNFVEEKYPASNRDIYLYGKEINDETYAICKSDMMIKGNNPENIRVGSTLSTDE  295

Query  282  HKDKRFHYMLSNPPYGVDWKKYQDPIKEEADTLGFSGRF-------------GAGTPRIS  328
               +RF++MLSNPPYG  W   Q  IKE  + ++  GRF               + PR S
Sbjct  296  FSSNRFDFMLSNPPYGKSWASEQKHIKEGKEVVD--GRFKVKLKDYWGVESEQEAIPRSS  353

Query  329  DGQLLFLQHMISKMRDDED---GSRIGIVMNGSPLFTGGAGSGESEIRRWMFENDWVEAI  385
            DGQLLFL +M++KM+  +D   GSRI+ V NGS+LFTG+AGSGES+IRR ++END ++AI
Sbjct  354  DGQLLFLMEMVTKMKSPQDSPLGSRIASVHNGSSLFTGDAGSGESNIRRYIIENDMLDAI  413

Query  386  VALPTDLFYNTGIQTYIWLLTNRKPANRQGKVQLIDASGERFWKSMRKSLGSKRREIPEE  445
            V LP +LFYNTGI TYIWLL N KP NRQGKVQLIDAS   + + +RK+LG+K  E++ E
Sbjct  414  VQLPNNLFYNTGITTYIWLLNNNKPENRQGKVQLIDAS--LLFRKLRKNLGNKNCEFSPE  471

Query  446  ARADIVRIY-------EGFLNGGNGEGDVAKIFDVDDFGYREIRIERPLRLNFQASHERI  498
              A+IV  Y        ++ + G+  G  A++F  +DFGY  + IERP R N Q   + I
Sbjct  472  HIAEIVSTYLENQSVERAIDEKGDPVGIAAQVFKNQDFGYYKVNIERPDRRNAQFRADLI  531

Query  499  ARLAKEKAFTRLPDDEQEEIEVVLLGMGDKLFTN--RKAFEKALTK  542
              L       R+ + ++E +E +    G++++     K++EK +TK
Sbjct  532  EPL-------RFENSQREVMEYLYAEYGEQVYDAGFVKGIEKEITK  570


 Score = 57.4 bits (198),  Expect = 2e-09, Method: Compositional matrix adjust.
 Identities = 35/90 (39%), Positives = 53/90 (59%), Gaps = 8/90 (8%)

Query  581  EPNTDLRDYEFVPLKEDWREYVAREVTPFAPDTWVDESYRDARDHEIGRIGYEINFNRYF  640
            E+++DLRD E VPL +   +Y   EV P   ++WV+         E  +IGYEI+FN+YF
Sbjct  702  ESSSDLRDSESVPLEQSIYQYFLDEVKPHVDEAWVN--------LESVKIGYEISFNKYF  753

Query  641  YRYAPPRPLEKIDVELKALETEIAELLREI  670
            YR  P R+++ +  E+ ALE     L+ +I
Sbjct  754  YRHKPLRSMDEVAKEIIALEQKAEGLIADI  783

72) Metme_4216 in NC_015572


> EU272902|18|G17|167832524|ACA01834.1|Vibrio_cholerae_Amazonia_3509|-|21794..24175|-|VPI2_0017c|DNA 
methylase HsdM
Length=793

 Score =  315 bits (1182),  Expect = 4e-87, Method: Compositional matrix adjust.
 Identities = 233/562 (42%), Positives = 354/562 (63%), Gaps = 68/562 (12%)

Query  1    MNGETHSQLANFIWSI---CNLLRGPYKRNEYRKVILPLTVLRRFDCLIAPSKDAAFEE-  56
            M+   H++L +FIWSI   C  LR+ Y R  YR VILP+ VLRR+D L+ PSK+A +EE 
Sbjct  1    MDHSVHNKLVSFIWSIADDC--LRDVYVRGKYRDVILPMVVLRRLDTLLEPSKEAVLEEV  58

Query  57   -FQSLKSKPERVIQARLQTITGHRFYNLSR----MQFDKNADHSilndpnnlapnlnnyi  111
             FQ    +   + +A L + +G  FYN S+      F   +++  +  +N          
Sbjct  59   RFQKEEMNEIELDDAPLCATSGYVFYNTSKWTLQTLFSTATNNQQILLANFEDYLNG---  115

Query  112  naFSPNVRAIMEKFKFSEQIAHMAEKNILFEVVKAFAA--IDLSP-----------QRVD  158
              FS NV+ I+E F++  QI HMA KN+L++VV  F +  I+L+P             + 
Sbjct  116  --FSENVKEIVECFNLKAQIRHMAGKNVLLDVVEKFVSPYINLTPAVKEDPEGNKLPALS  173

Query  159  NVQMGYVFEELIRIGAEQSNEEAGEHFTPREVIKLMVNLLLVPEQDLAQSHVVKTIYDPA  218
            N+ MGYVFEELIR   E++NEEAGEHFTPREVI LM +L++ P +D  +  +  T+YDPA
Sbjct  174  NLGMGYVFEELIRKFNEENNEEAGEHFTPREVIELMTHLVFDPIKD--NLPLSITVYDPA  231

Query  219  CGTGGMLSVAEEYIRKLNADAQPK--LFGQDFNDEAWAVCKSDMLIKGEDADNVILGDTF  276
            CG+GGML+ +++++    + ++    L+G+++NDE+ A+CKSDM+IKG++++N+ +G T+
Sbjct  232  CGSGGMLTETQNFVEEKYPASNRDIYLYGKEINDETYAICKSDMMIKGNNPENIRVGSTL  291

Query  277  TRDGFDRDNDGNKWTFDYMLANPPFGVEWKQQQKHIQQETDTLGFAGRF-----------  325
            + D F  +       FD+ML+NPP+G  W  +QKHI++  + ++  GRF           
Sbjct  292  STDEFSSNR------FDFMLSNPPYGKSWASEQKHIKEGKEVVD--GRFKVKLKDYWGVE  343

Query  326  --GAGTPRINDGAFLFLQHMIAKMRPVSAG--GSRIGIVFNGSPLFTGDAGSGESEIRRW  381
                + PR +DG +LFL +M++KM++   +  GSRI+ V NGS+LFTGDAGSGES+IRR 
Sbjct  344  SEQEAIPRSSDGQLLFLMEMVTKMKSPQDSPLGSRIASVHNGSSLFTGDAGSGESNIRRY  403

Query  382  LIENDWLEAIVALPEQLFYNTGISTYIWIVSNRKEPQRKGKVQLIDARNFWVPMEKSLGN  441
            +IEND L+AIV LP++LFYNTGI+TYIW+++N K  +R+GKVQLIDA  +   + K+LGN
Sbjct  404  IIENDMLDAIVQLPNNLFYNTGITTYIWLLNNNKPENRQGKVQLIDASLLFRKLRKNLGN  463

Query  442  KRRRIGDPSDKAKDPDHIGDITRIYASFSDGETRLFTLDGKDKEL-VVNKLFDNEDFGYH  500
            K   ++        P+HI++I   Y   +++  R  ++D K+  + +  ++F N+DFGY 
Sbjct  464  KNCEFS--------PEHIAEIVSTYLE-NQSVER--AIDEKGDPVGIAAQVFKNQDFGYY  512

Query  501  KITVERPLRLNFQASAERIARL  522
            K+ +ERP R N Q  A+ I  L
Sbjct  513  KVNIERPDRRNAQFRADLIEPL  534


 Score = 76.0 bits (269),  Expect = 6e-15, Method: Compositional matrix adjust.
 Identities = 38/82 (47%), Positives = 58/82 (71%), Gaps = 0/82 (0%)

Query  623  EPDADLRDTETVPLKQSIDEYFQREVLPHVPDAWIDHSKTKVGYEIPLNRHFYRYEPPRA  682
            E+ +DLRD+E+VPL QSI +YF  EV PHV +AW++    K+GYEI++N+ FYR  P R+
Sbjct  702  ESSSDLRDSESVPLEQSIYQYFLDEVKPHVDEAWVNLESVKIGYEISFNKYFYRHKPLRS  761

Query  683  LEVIEAEIKALEGEIVDLLREV  704
            ++ +  EI ALE    +L+ ++
Sbjct  762  MDEVAKEIIALEQKAEGLIADI  783