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PAthogenisity Island DataBase (PAI DB)

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Homologs of polA gene of NC_007297_P1

499

protein-level

Hit (GenBank Accn)

Product

Source Genome

Eval.

Ident.(%)

1) polA
( YP_006932255.1 )

DNA polymerase I family protein

NC_018936
(Streptococcus pyogenes A20)

0.0

100

2) polA
( YP_007586735.1 )

DNA polymerase I

NC_020540
(Streptococcus pyogenes M1 476)

0.0

100

3) polA
( YP_281523.1 )

DNA polymerase I

NC_007297
(Streptococcus pyogenes MGAS5005)

0.0

100

4) polA
( YP_595893.1 )

DNA polymerase I

NC_008021
(Streptococcus pyogenes MGAS9429)

0.0

100

5) pol
( YP_001127749.1 )

DNA polymerase I

NC_009332
(Streptococcus pyogenes Manfredo)

0.0

6) spyM18_0184
( NP_606485.1 )

DNA polymerase I

NC_003485
(Streptococcus pyogenes MGAS8232)

0.0

7) L897_01030
( YP_008242500.1 )

DNA polymerase I

NC_021807
(Streptococcus pyogenes HSC5)

0.0

8) polA
( YP_597770.1 )

DNA polymerase I

NC_008022
(Streptococcus pyogenes MGAS10270)

0.0

9) polA
( NP_268564.1 )

DNA polymerase I

NC_002737
(Streptococcus pyogenes SF370)

0.0

10) polA
( YP_006071361.1 )

DNA polymerase I family protein

NC_017596
(Streptococcus pyogenes Alab49)

0.0

11) polA.1
( NP_663949.1 )

DNA polymerase I

NC_004070
(Streptococcus pyogenes MGAS315)

0.0

12) SPs0149
( NP_801411.1 )

DNA polymerase I

NC_004606
(Streptococcus pyogenes SSI-1)

0.0

13) polA
( YP_601659.1 )

DNA polymerase I

NC_008024
(Streptococcus pyogenes MGAS10750)

0.0

14) polA
( YP_279626.1 )

DNA polymerase I

NC_007296
(Streptococcus pyogenes MGAS6180)

0.0

15) SDE12394_10115
( YP_006014017.1 )

DNA polymerase I

NC_017567
(Streptococcus dysgalactiae ATCC 12394)

0.0

16) M6_Spy0205
( YP_059523.1 )

DNA polymerase I

NC_006086
(Streptococcus pyogenes MGAS10394)

0.0

17) polA
( YP_005388256.1 )

DNA-directed DNA polymerase I PolA/PolI

NC_017040
(Streptococcus pyogenes MGAS15252)

0.0

18) polA
( YP_005410963.1 )

DNA-directed DNA polymerase I PolA/PolI

NC_017053
(Streptococcus pyogenes MGAS1882)

0.0

19) polA
( YP_002285207.1 )

DNA polymerase I

NC_011375
(Streptococcus pyogenes NZ131)

0.0

20) polA
( YP_006860458.1 )

DNA polymerase I

NC_018712
(Streptococcus dysgalactiae RE378)

0.0

21) SDEG_2002
( YP_002997698.1 )

DNA polymerase I

NC_012891
(Streptococcus dysgalactiae GGS_124)

0.0

22) SEQ_0252
( YP_002745662.1 )

DNA polymerase I

NC_012471
(Streptococcus equi 4047)

0.0

23) SZO_01560
( YP_002743718.1 )

DNA polymerase I

NC_012470
(Streptococcus equi H70)

0.0

24) polA
( YP_599766.1 )

DNA polymerase I

NC_008023
(Streptococcus pyogenes MGAS2096)

0.0

100

25) polA
( YP_002122573.1 )

DNA polymerase I

NC_011134
(Streptococcus equi MGCS10565)

0.0

26) polA
( YP_006905636.1 )

DNA polymerase I

NC_019042
(Streptococcus dysgalactiae AC-2713)

0.0

27) polA
( YP_006042086.1 )

DNA polymerase I

NC_017582
(Streptococcus equi ATCC 35246)

0.0

28) K710_2019
( YP_008057698.1 )

DNA-directed DNA polymerase

NC_021314
(Streptococcus iniae SF1)

0.0

29) polA
( YP_004479854.1 )

DNA polymerase I

NC_015558
(Streptococcus parauberis KCTC 11537)

0.0

30) polA
( YP_002562989.1 )

DNA polymerase I

NC_012004
(Streptococcus uberis 0140J)

0.0

31) polA
( YP_004728665.1 )

DNA polymerase I

NC_015760
(Streptococcus salivarius CCHSS3)

0.0

32) polA
( YP_006070965.1 )

DNA polymerase I

NC_017595
(Streptococcus salivarius JIM8777)

0.0

33) polI
( YP_003485588.1 )

DNA polymerase I

NC_013928
(Streptococcus mutans NN2025)

0.0

34) polI
( NP_720755.1 )

DNA polymerase I

NC_004350
(Streptococcus mutans UA159)

0.0

35) SMUGS5_01195
( YP_006489562.1 )

DNA polymerase I

NC_018089
(Streptococcus mutans GS-5)

0.0

36) polI
( YP_006251947.1 )

DNA polymerase I

NC_017768
(Streptococcus mutans LJ23)

0.0

37) polA
( YP_004622541.1 )

DNA-directed DNA polymerase I

NC_015678
(Streptococcus parasanguinis ATCC 15912)

0.0

38) polA
( YP_006308953.1 )

DNA polymerase I

NC_017905
(Streptococcus parasanguinis FW213)

0.0

39) STER_1736
( YP_821073.1 )

DNA polymerase I

NC_008532
(Streptococcus thermophilus LMD-9)

0.0

40) STND_1696
( YP_006003235.1 )

DNA polymerase I

NC_017563
(Streptococcus thermophilus ND03)

0.0

41) polA
( YP_006041633.1 )

DNA-directed DNA polymerase I

NC_017581
(Streptococcus thermophilus JIM 8232)

0.0

42) Y1U_C1648
( YP_006340762.1 )

DNA polymerase I

NC_017927
(Streptococcus thermophilus MN-ZLW-002)

0.0

43) polA
( YP_142094.1 )

DNA polymerase I

NC_006449
(Streptococcus thermophilus CNRZ1066)

0.0

44) polA
( YP_140175.1 )

DNA polymerase I

NC_006448
(Streptococcus thermophilus LMG 18311)

0.0

45) BSA_4690
( YP_008084131.1 )

DNA polymerase I

NC_021485
(Streptococcus agalactiae 09mas018883)

0.0

46) polA
( NP_687423.1 )

DNA polymerase I

NC_004116
(Streptococcus agalactiae 2603V/R)

0.0

47) polA
( YP_329109.1 )

DNA polymerase I

NC_007432
(Streptococcus agalactiae A909)

0.0

48) polA
( YP_006763636.1 )

DNA polymerase I

NC_018646
(Streptococcus agalactiae GD201008-001)

0.0

49) polA
( NP_734893.1 )

DNA polymerase I

NC_004368
(Streptococcus agalactiae NEM316)

0.0

50) MSA_4610
( YP_008086212.1 )

DNA polymerase I

NC_021486
(Streptococcus agalactiae ILRI005)

0.0

51) SAIL_4710
( YP_008117100.1 )

DNA polymerase I

NC_021507
(Streptococcus agalactiae ILRI112)

0.0

52) polA
( YP_005095637.1 )

DNA polymerase I

NC_016749
(Streptococcus macedonicus ACA-DC 198)

0.0

53) polA
( YP_007967989.1 )

DNA polymerase I

NC_021195
(Streptococcus agalactiae 2-22)

0.0

54) polA
( YP_006950784.1 )

DNA polymerase

NC_019048
(Streptococcus agalactiae SA20-06)

0.0

55) polI
( YP_001449466.1 )

DNA polymerase I

NC_009785
(Streptococcus gordonii Challis)

0.0

56) I872_00430
( YP_007922375.1 )

DNA polymerase I

NC_021175
(Streptococcus oligofermentans AS 1.3089)

0.0

57) polA
( YP_001034111.1 )

DNA polymerase I

NC_009009
(Streptococcus sanguinis SK36)

0.0

58) polA
( YP_008513668.1 )

DNA polymerase I

NC_022246
(Streptococcus intermedius B196)

0.0

59) polA
( YP_008497874.1 )

DNA polymerase I

NC_022237
(Streptococcus intermedius C270)

0.0

60) polA
( YP_008499683.1 )

DNA polymerase I

NC_022238
(Streptococcus constellatus C1050)

0.0

61) polA
( YP_008496108.1 )

DNA polymerase I

NC_022236
(Streptococcus constellatus C232)

0.0

62) polA
( YP_008511869.1 )

DNA polymerase I

NC_022245
(Streptococcus constellatus C818)

0.0

63) polA
( YP_006080092.1 )

DNA polymerase I

NC_017620
(Streptococcus suis D9)

0.0

64) polA
( YP_006076689.1 )

DNA polymerase I

NC_017618
(Streptococcus suis JS14)

0.0

65) NJAUSS_1282
( YP_007571229.1 )

DNA polymerase I

NC_020526
(Streptococcus suis SC070731)

0.0

66) polA
( YP_006358490.1 )

DNA polymerase I

NC_017950
(Streptococcus suis ST1)

0.0

67) polA
( YP_008501644.1 )

DNA polymerase I

NC_022239
(Streptococcus anginosus C238)

0.0

68) polA
( YP_006082145.1 )

DNA polymerase I

NC_017621
(Streptococcus suis D12)

0.0

69) polA
( YP_004401251.1 )

DNA polymerase I

NC_015433
(Streptococcus suis ST3)

0.0

70) polA
( YP_006470462.1 )

DNA polymerase I

NC_018073
(Streptococcus intermedius JTH08)

0.0

71) polA
( YP_007974976.1 )

DNA polymerase I

NC_021213
(Streptococcus suis TL13)

0.0

72) polA
( YP_006034903.1 )

DNA polymerase I

NC_017576
(Streptococcus gallolyticus ATCC 43143)

0.0

73) polA
( YP_004289023.1 )

DNA polymerase I

NC_015215
(Streptococcus gallolyticus ATCC BAA-2069)

0.0

74) polA
( YP_003431515.1 )

DNA polymerase I

NC_013798
(Streptococcus gallolyticus UCN34)

0.0

75) polA
( YP_008510111.1 )

DNA polymerase I

NC_022244
(Streptococcus anginosus C1051)

0.0

76) SSU05_1378
( YP_001198744.1 )

DNA polymerase I

NC_009442
(Streptococcus suis 05ZYH33)

0.0

77) SSU98_1393
( YP_001200951.1 )

DNA polymerase I

NC_009443
(Streptococcus suis 98HAH33)

0.0

78) SSUA7_1222
( YP_006084884.1 )

DNA polymerase I

NC_017622
(Streptococcus suis A7)

0.0

79) polA
( YP_003028343.1 )

DNA polymerase I

NC_012926
(Streptococcus suis BM407)

0.0

80) SSGZ1_1224
( YP_006074623.1 )

DNA polymerase I

NC_017617
(Streptococcus suis GZ1)

0.0

81) polA
( YP_003027063.1 )

DNA polymerase I

NC_012925
(Streptococcus suis P1/7)

0.0

82) YYK_05770
( YP_006650069.1 )

DNA polymerase I

NC_018526
(Streptococcus suis S735)

0.0

83) polA
( YP_003025238.1 )

DNA polymerase I

NC_012924
(Streptococcus suis SC84)

0.0

84) SSU12_1273
( YP_006078700.1 )

DNA polymerase I

NC_017619
(Streptococcus suis SS12)

0.0

85) polA
( YP_004559985.1 )

DNA polymerase I

NC_015600
(Streptococcus pasteurianus ATCC 43144)

0.0

86) KE3_1916
( YP_008357175.1 )

DNA polymerase I

NC_021900
(Streptococcus lutetiensis 033)

0.0

87) polA
( YP_005204612.1 )

DNA polymerase I

NC_016826
(Streptococcus infantarius CJ18)

0.0

88) polI
( YP_004326927.1 )

DNA-directed DNA polymerase

NC_015291
(Streptococcus oralis Uo5)

0.0

89) polI
( YP_003445215.1 )

DNA-directed DNA polymerase

NC_013853
(Streptococcus mitis B6)

0.0

90) SPPN_00560
( YP_004767416.1 )

DNA polymerase I

NC_015875
(Streptococcus pseudopneumoniae IS7493)

0.0

91) polA
( YP_002036753.1 )

DNA polymerase I

NC_011072
(Streptococcus pneumoniae G54)

0.0

92) polA
( YP_006067532.1 )

DNA polymerase I

NC_017594
(Streptococcus salivarius 57.I)

0.0

93) SP70585_0092
( YP_002739404.1 )

DNA polymerase I

NC_012468
(Streptococcus pneumoniae 70585)

0.0

94) polA
( YP_006702352.1 )

DNA polymerase I

NC_018594
(Streptococcus pneumoniae A45)

0.0

95) polA
( YP_002510134.1 )

DNA polymerase I

NC_011900
(Streptococcus pneumoniae ATCC 700669)

0.0

96) SPD_0038
( YP_815461.1 )

DNA polymerase I

NC_008533
(Streptococcus pneumoniae D39)

0.0

97) polA
( NP_357626.1 )

DNA polymerase I

NC_003098
(Streptococcus pneumoniae R6)

0.0

98) MYY_0106
( YP_006252304.1 )

DNA polymerase I

NC_017769
(Streptococcus pneumoniae ST556)

0.0

99) SPT_0070
( YP_002741582.1 )

DNA polymerase I

NC_012469
(Streptococcus pneumoniae Taiwan19F-14)

0.0

100) polA
( YP_003723761.1 )

DNA-directed DNA polymerase

NC_014251
(Streptococcus pneumoniae TCH8431/19A)

0.0

101) SPAP_0083
( YP_003875679.1 )

DNA polymerase I - 3'-5' exonuclease and polymerase domains

NC_014494
(Streptococcus pneumoniae AP200)

0.0

102) polA
( YP_006742303.1 )

DNA-directed DNA polymerase I

NC_018630
(Streptococcus pneumoniae gamPNI0373)

0.0

103) polA
( YP_006065390.1 )

DNA polymerase I

NC_017593
(Streptococcus pneumoniae INV200)

0.0

104) SPP_0095
( YP_002737330.1 )

DNA polymerase I

NC_012467
(Streptococcus pneumoniae P1031)

0.0

105) SP_0032
( NP_344582.1 )

DNA polymerase I

NC_003028
(Streptococcus pneumoniae TIGR4)

0.0

106) polA
( YP_006061737.1 )

DNA polymerase I

NC_017591
(Streptococcus pneumoniae INV104)

0.0

107) polA
( YP_007765423.1 )

DNA polymerase I

NC_021006
(Streptococcus pneumoniae SNP034156)

0.0

108) polA
( YP_001834749.1 )

DNA polymerase I

NC_010582
(Streptococcus pneumoniae CGSP14)

0.0

109) SPH_0131
( YP_001693553.1 )

DNA polymerase I

NC_010380
(Streptococcus pneumoniae Hungary19A-6)

0.0

110) polA
( YP_006063607.1 )

DNA polymerase I

NC_017592
(Streptococcus pneumoniae OXC141)

0.0

111) polA
( YP_007813771.1 )

DNA polymerase I

NC_021028
(Streptococcus pneumoniae SNP034183)

0.0

112) polA
( YP_007811952.1 )

DNA polymerase I

NC_021026
(Streptococcus pneumoniae SNP994038)

0.0

113) polA
( YP_007762626.1 )

DNA polymerase I

NC_021005
(Streptococcus pneumoniae SNP994039)

0.0

114) SPJ_0056
( YP_002735172.1 )

DNA polymerase I

NC_012466
(Streptococcus pneumoniae JJA)

0.0

115) SP670_0108
( YP_003878290.1 )

DNA polymerase I

NC_014498
(Streptococcus pneumoniae 670-6B)

0.0

116) polA
( NP_268299.1 )

DNA polymerase I

NC_002662
(Lactococcus lactis IL1403)

0.0

117) polA
( YP_005869529.1 )

DNA polymerase I

NC_017486
(Lactococcus lactis CV56)

0.0

118) polA
( YP_007509444.1 )

DNA polymerase I

NC_020450
(Lactococcus lactis IO-1)

0.0

119) polA
( YP_003354781.1 )

DNA polymerase I

NC_013656
(Lactococcus lactis KF147)

0.0

120) polA
( YP_008569825.1 )

DNA polymerase I PolA

NC_022369
(Lactococcus lactis KW2)

0.0

121) polA
( YP_001033666.1 )

DNA polymerase I

NC_009004
(Lactococcus lactis MG1363)

0.0

122) LLNZ_12535
( YP_006357814.1 )

DNA polymerase I

NC_017949
(Lactococcus lactis NZ9000)

0.0

123) LACR_2445
( YP_812001.1 )

DNA polymerase I

NC_008527
(Lactococcus lactis SK11)

0.0

124) polA
( YP_007000371.1 )

DNA polymerase I

NC_019435
(Lactococcus lactis UC509.9)

0.0

125) LCGL_1869
( YP_005871613.1 )

DNA polymerase I

NC_017490
(Lactococcus garvieae Lg2)

0.0

126) LCGT_1848
( YP_004780025.1 )

DNA polymerase I

NC_015930
(Lactococcus garvieae ATCC 49156)

0.0

127) llh_12435
( YP_005877086.1 )

DNA polymerase I

NC_017492
(Lactococcus lactis A76)

0.0

128) EFAU004_01550
( YP_005354752.1 )

DNA polymerase I

NC_017022
(Enterococcus faecium Aus0004)

0.0

129) EFAU085_01632
( YP_008395154.1 )

DNA polymerase I

NC_021994
(Enterococcus faecium AUS0085)

0.0

130) polA
( YP_006376168.1 )

DNA-directed DNA polymerase I

NC_017960
(Enterococcus faecium DO)

0.0

131) M7W_1304
( YP_007393988.1 )

DNA polymerase I

NC_020207
(Enterococcus faecium NRRL B-2354)

0.0

132) EFD32_0689
( YP_006537056.1 )

DNA polymerase I

NC_018221
(Enterococcus faecalis D32)

0.0

133) polA
( YP_007152495.1 )

DNA polymerase I

NC_019770
(Enterococcus faecalis Symbioflor 1)

0.0

134) polA
( NP_814617.1 )

DNA polymerase I

NC_004668
(Enterococcus faecalis V583)

0.0

135) ENT_22130
( YP_007808419.1 )

DNA polymerase I

NC_021023
(Enterococcus sp. 7L76)

0.0

136) polA
( YP_005707663.1 )

DNA-directed DNA polymerase I

NC_017316
(Enterococcus faecalis OG1RF)

0.0

137) ECBG_00868
( YP_007752737.1 )

DNA polymerase I

NC_020995
(Enterococcus casseliflavus EC20)

0.0

138) polA
( YP_004886996.1 )

DNA polymerase I

NC_016052
(Tetragenococcus halophilus NBRC 12172)

0.0

139) MPTP_1619
( YP_004456856.1 )

DNA polymerase I

NC_015516
(Melissococcus plutonius ATCC 35311)

0.0

140) MPD5_0433
( YP_005319202.1 )

DNA polymerase I

NC_016938
(Melissococcus plutonius DAT561)

0.0

141) polA
( YP_006991899.2 )

DNA polymerase I family protein

NC_019425
(Carnobacterium maltaromaticum LMA28)

0.0

142) polA
( YP_003062846.1 )

DNA-directed DNA polymerase I

NC_012984
(Lactobacillus plantarum JDM1)

0.0

143) polA
( YP_004889348.1 )

DNA-directed DNA polymerase I

NC_004567
(Lactobacillus plantarum WCFS1)

0.0

144) polA
( YP_003924501.1 )

DNA-directed DNA polymerase I

NC_014554
(Lactobacillus plantarum ST-III)

0.0

145) polA
( YP_007414201.1 )

DNA polymerase

NC_020229
(Lactobacillus plantarum ZJ316)

0.0

146) Lp16_1139
( YP_008120969.1 )

DNA-directed DNA polymerase I

NC_021514
(Lactobacillus plantarum 16)

0.0

147) polA
( YP_007986787.1 )

DNA polymerase I

NC_021224
(Lactobacillus plantarum P-8)

0.0

148) polA
( YP_396016.1 )

DNA-directed DNA polymerase I

NC_007576
(Lactobacillus sakei 23K)

0.0

149) polA
( YP_004374439.1 )

DNA polymerase I

NC_015391
(Carnobacterium sp. 17-4)

0.0

150) polA
( YP_005873354.1 )

DNA polymerase I family protein

NC_017491
(Lactobacillus rhamnosus ATCC 8530)

0.0

151) LOCK900_1700
( YP_008203322.1 )

DNA polymerase I

NC_021723
(Lactobacillus rhamnosus LOCK900)

0.0

152) LOCK908_1794
( YP_008206287.1 )

DNA polymerase I

NC_021725
(Lactobacillus rhamnosus LOCK908)

0.0

153) polA
( YP_003602003.1 )

DNA polymerase i

NC_014106
(Lactobacillus crispatus ST1)

0.0

154) polA
( YP_003171507.1 )

DNA polymerase I

NC_013198
(Lactobacillus rhamnosus GG)

0.0

155) LRHM_1697
( YP_005866189.1 )

DNA polymerase I

NC_017482
(Lactobacillus rhamnosus GG)

0.0

156) LCBD_1905
( YP_005859942.1 )

DNA polymerase I

NC_017474
(Lactobacillus casei BD-II)

0.0

157) LC2W_1884
( YP_005856800.1 )

DNA polymerase I

NC_017473
(Lactobacillus casei LC2W)

0.0

158) polA
( YP_006751959.1 )

DNA polymerase I

NC_018641
(Lactobacillus casei W56)

0.0

159) polA
( YP_001987865.1 )

DNA-directed DNA polymerase I

NC_010999
(Lactobacillus casei BL23)

0.0

160) LBPG_00987
( YP_008446969.1 )

DNA polymerase I

NC_022112
(Lactobacillus paracasei 8700:2)

0.0

161) LVIS_1042
( YP_795206.1 )

DNA polymerase I

NC_008497
(Lactobacillus brevis ATCC 367)

0.0

162) LVISKB_0929
( YP_007653769.1 )

DNA polymerase I

NC_020819
(Lactobacillus brevis KB290)

0.0

163) LSEI_1709
( YP_806924.1 )

DNA polymerase I

NC_008526
(Lactobacillus casei ATCC 334)

0.0

164) LOCK919_1880
( YP_008200391.1 )

DNA polymerase I

NC_021721
(Lactobacillus casei LOCK919)

0.0

165) LCAZH_1699
( YP_003788777.1 )

DNA polymerase I - 3'-5' exonuclease and polymerase domains

NC_014334
(Lactobacillus casei Zhang)

0.0

166) lhv_1617
( YP_001577834.1 )

DNA polymerase

NC_010080
(Lactobacillus helveticus DPC 4571)

0.0

167) LDBND_1445
( YP_004034451.1 )

DNA polymerase i

NC_014727
(Lactobacillus delbrueckii ND02)

0.0

168) polA
( YP_003293572.1 )

DNA polymerase I

NC_013504
(Lactobacillus johnsonii FI9785)

0.0

169) LBU_1297
( YP_005852506.1 )

DNA polymerase I

NC_017469
(Lactobacillus delbrueckii 2038)

0.0

170) LJ1651
( NP_965458.1 )

DNA polymerase I

NC_005362
(Lactobacillus johnsonii NCC 533)

0.0

171) LJP_1393c
( YP_005862665.1 )

DNA polymerase I

NC_017477
(Lactobacillus johnsonii DPC 6026)

0.0

172) polA
( YP_619338.1 )

DNA polymerase I

NC_008054
(Lactobacillus delbrueckii ATCC 11842)

0.0

173) LBUL_1407
( YP_813358.1 )

DNA polymerase I

NC_008529
(Lactobacillus delbrueckii ATCC BAA-365)

0.0

174) WANG_0240
( YP_004562037.1 )

DNA polymerase I

NC_015602
(Lactobacillus kefiranofaciens ZW3)

0.0

175) LGAS_1421
( YP_815220.1 )

DNA polymerase I

NC_008530
(Lactobacillus gasseri ATCC 33323)

0.0

176) polA
( YP_008236858.1 )

DNA polymerase I PolA

NC_021744
(Lactobacillus helveticus CNRZ32)

0.0

177) polA
( YP_006725960.1 )

DNA polymerase I

NC_018610
(Lactobacillus buchneri CD034)

0.0

178) Lbuc_1217
( YP_004398535.1 )

DNA polymerase I

NC_015428
(Lactobacillus buchneri NRRL B-30929)

0.0

179) LAB52_07810
( YP_005854486.1 )

DNA polymerase I

NC_017470
(Lactobacillus amylovorus GRL1118)

0.0

180) LBFF_1431
( YP_007995607.1 )

DNA polymerase I

NC_021235
(Lactobacillus fermentum F-6)

0.0

181) LBHH_0560
( YP_005849771.1 )

DNA polymerase I

NC_017467
(Lactobacillus helveticus H10)

0.0

182) LAC30SC_08380
( YP_004292716.1 )

DNA polymerase I

NC_015214
(Lactobacillus acidophilus 30SC)

0.0

183) LC40_0841
( YP_005848927.1 )

DNA-directed DNA polymerase

NC_017465
(Lactobacillus fermentum CECT 5716)

0.0

184) LA14_1542
( YP_007938384.1 )

DNA polymerase I

NC_021181
(Lactobacillus acidophilus La-14)

0.0

185) polA
( YP_194398.1 )

DNA polymerase I

NC_006814
(Lactobacillus acidophilus NCFM)

0.0

186) LA2_08635
( YP_004032431.1 )

DNA polymerase

NC_014724
(Lactobacillus amylovorus GRL 1112)

0.0

187) LAF_1317
( YP_001844133.1 )

DNA-directed DNA polymerase I

NC_010610
(Lactobacillus fermentum IFO 3956)

0.0

188) R0052_03345
( YP_006655425.1 )

DNA polymerase I

NC_018528
(Lactobacillus helveticus R0052)

0.0

189) polA
( YP_535380.1 )

DNA polymerase I

NC_007929
(Lactobacillus salivarius UCC118)

0.0

190) polA
( NP_693084.1 )

DNA polymerase I

NC_004193
(Oceanobacillus iheyensis HTE831)

0.0

191) polA
( YP_005863519.1 )

DNA polymerase I

NC_017481
(Lactobacillus salivarius CECT 5713)

0.0

192) N134_06975
( YP_008326681.1 )

DNA polymerase I

NC_021872
(Lactobacillus reuteri TD1)

0.0

193) PEPE_0688
( YP_804191.1 )

DNA polymerase I

NC_008525
(Pediococcus pentosaceus ATCC 25745)

0.0

194) polA
( YP_004648764.1 )

DNA-directed DNA polymerase I

NC_015697
(Lactobacillus reuteri SD2112)

0.0

195) Lreu_1247
( YP_001271841.1 )

DNA polymerase I

NC_009513
(Lactobacillus reuteri DSM 20016)

0.0

196) LAR_1181
( YP_001842177.1 )

DNA-directed DNA polymerase I

NC_010609
(Lactobacillus reuteri JCM 1112)

0.0

197) LRI_0722
( YP_008099076.1 )

DNA-directed DNA polymerase I

NC_021494
(Lactobacillus reuteri I5007)

0.0

198) polA
( YP_004832294.1 )

DNA polymerase I

NC_015975
(Lactobacillus ruminis ATCC 27782)

0.0

199) polA
( YP_004321655.1 )

DNA-directed DNA polymerase

NC_015278
(Aerococcus urinae ACS-120-V-Col10a)

0.0

200) polA
( YP_002314879.1 )

DNA polymerase I

NC_011567
(Anoxybacillus flavithermus WK1)

0.0

201) C270_03045
( YP_006795521.1 )

DNA polymerase I

NC_018673
(Leuconostoc carnosum JB16)

0.0

202) Geoth_0907
( YP_004586986.1 )

DNA polymerase I

NC_015660
(Geobacillus thermoglucosidasius C56-YS93)

0.0

203) Bcer98_3272
( YP_001376486.1 )

DNA polymerase I

NC_009674
(Bacillus cytotoxicus NVH 391-98)

0.0

204) GY4MC1_0838
( YP_003988264.1 )

DNA polymerase I

NC_014650
(Geobacillus sp. Y4.1MC1)

0.0

205) GWCH70_2673
( YP_002950632.1 )

DNA polymerase I

NC_012793
(Geobacillus sp. WCH70)

0.0

206) SSIL_1198
( YP_006461767.1 )

DNA polymerase I

NC_018065
(Solibacillus silvestris StLB046)

0.0

207) polA
( YP_006844833.1 )

DNA polymerase I

NC_018704
(Amphibacillus xylanus NBRC 15112)

0.0

208) polA
( YP_002751942.1 )

DNA polymerase I

NC_012472
(Bacillus cereus 03BB102)

0.0

209) bcf_22975
( YP_005121227.1 )

DNA polymerase I

NC_016779
(Bacillus cereus F837/76)

0.0

210) polA
( YP_896885.1 )

DNA polymerase I

NC_008600
(Bacillus thuringiensis Al Hakam)

0.0

211) polA
( YP_085907.1 )

DNA polymerase I

NC_006274
(Bacillus cereus E33L)

0.0

212) polA
( YP_038632.1 )

DNA polymerase I

NC_005957
(Bacillus thuringiensis 97-27)

0.0

213) polA
( YP_002532105.1 )

DNA polymerase i

NC_011969
(Bacillus cereus Q1)

0.0

214) YBT020_22555
( YP_005568157.1 )

DNA polymerase I

NC_017200
(Bacillus thuringiensis YBT-020)

0.0

215) polA
( YP_005005080.1 )

DNA polymerase I

NC_016605
(Pediococcus claussenii ATCC BAA-344)

0.0

216) polA
( YP_002340636.1 )

DNA polymerase I

NC_011658
(Bacillus cereus AH187)

0.0

217) polA
( YP_003794303.1 )

DNA polymerase I

NC_014335
(Bacillus cereus CI)

0.0

218) BCN_4487
( YP_005107020.1 )

DNA polymerase I

NC_016771
(Bacillus cereus NC7401)

0.0

219) polA
( YP_004840967.1 )

DNA polymerase I

NC_015978
(Lactobacillus sanfranciscensis TMW 1.1304)

0.0

220) GTNG_2654
( YP_001126744.1 )

DNA polymerase I

NC_009328
(Geobacillus thermodenitrificans NG80-2)

0.0

221) polA
( YP_002448151.1 )

DNA polymerase I

NC_011772
(Bacillus cereus G9842)

0.0

222) BTF1_21475
( YP_006612384.1 )

DNA polymerase I

NC_018508
(Bacillus thuringiensis HD-789)

0.0

223) BTG_25930
( YP_006606622.1 )

DNA polymerase I

NC_018500
(Bacillus thuringiensis HD-771)

0.0

224) polA
( YP_002369383.1 )

DNA polymerase I

NC_011725
(Bacillus cereus B4264)

0.0

225) HD73_4882
( YP_007423981.1 )

DNA polymerase I

NC_020238
(Bacillus cereus HD73)

0.0

226) polA
( YP_003599923.1 )

DNA polymerase I

NC_014103
(Bacillus megaterium DSM 319)

0.0

227) polA
( YP_003565200.1 )

DNA polymerase I

NC_014019
(Bacillus megaterium QM B1551)

0.0

228) A284_05335
( YP_007384828.1 )

DNA polymerase I

NC_020164
(Staphylococcus warneri SG1)

0.0

229) polA
( YP_002868866.1 )

DNA polymerase I

NC_012659
(Bacillus anthracis A0248)

0.0

230) polA
( NP_847034.1 )

DNA polymerase I

NC_003997
(Bacillus anthracis Ames)

0.0

231) polA
( YP_021476.2 )

DNA polymerase I

NC_007530
(Bacillus anthracis Ames Ancestor)

0.0

232) polA
( YP_002817380.1 )

DNA polymerase I

NC_012581
(Bacillus anthracis CDC 684)

0.0

233) H9401_4610
( YP_006211664.1 )

DNA polymerase I

NC_017729
(Bacillus anthracis H9401)

0.0

234) BAS4482
( YP_030729.1 )

DNA polymerase I

NC_005945
(Bacillus anthracis Sterne)

0.0

235) polA
( YP_002453648.1 )

DNA polymerase I

NC_011773
(Bacillus cereus AH820)

0.0

236) BC4587
( NP_834293.1 )

DNA polymerase I

NC_004722
(Bacillus cereus ATCC 14579 )

0.0

237) MC28_3865
( YP_006830686.1 )

DeoR family transcriptional regulator

NC_018693
(Bacillus thuringiensis MC28)

0.0

238) polA
( YP_001728398.1 )

DNA polymerase I

NC_010471
(Leuconostoc citreum KM20)

0.0

239) polA
( YP_003666759.1 )

DNA polymerase I

NC_014171
(Bacillus thuringiensis BMB171)

0.0

240) polA
( YP_005492680.1 )

DNA polymerase I

NC_017138
(Bacillus megaterium WSH-002)

0.0

241) polA2
( YP_006929354.1 )

DNA polymerase I

NC_018877
(Bacillus thuringiensis Bt407)

0.0

242) polA
( YP_005574557.1 )

DNA polymerase I

NC_017208
(Bacillus thuringiensis CT-43)

0.0

243) H175_ch4680
( YP_007481138.1 )

DNA polymerase I

NC_020376
(Bacillus thuringiensis IS5056)

0.0

244) polA
( NP_981011.1 )

DNA polymerase I

NC_003909
(Bacillus cereus ATCC 10987)

0.0

245) polA
( YP_006015222.1 )

DNA polymerase I

NC_017568
(Staphylococcus pseudintermedius ED99)

0.0

246) polA
( NP_244019.1 )

DNA polymerase I

NC_002570
(Bacillus halodurans C-125)

0.0

247) BCK_12285
( YP_006596558.1 )

DNA polymerase I

NC_018491
(Bacillus cereus FRI-35)

0.0

248) BcerKBAB4_4417
( YP_001647204.1 )

DNA polymerase I

NC_010184
(Bacillus weihenstephanensis KBAB4)

0.0

249) Bsph_4111
( YP_001699707.1 )

DNA polymerase I

NC_010382
(Lysinibacillus sphaericus C3-41)

0.0

250) polA
( YP_005562120.1 )

DNA polymerase I

NC_017196
(Bacillus subtilis BEST195)

0.0

251) polA
( YP_003772238.1 )

DNA polymerase I

NC_014319
(Leuconostoc gasicomitatum LMG 18811)

0.0

252) polA
( NP_390787.1 )

DNA polymerase I

NC_000964
(Bacillus subtilis 168)

0.0

253) polA
( YP_007534896.1 )

DNA polymerase I PolA

NC_020507
(Bacillus subtilis 6051-HGW)

0.0

254) polA
( YP_006631008.1 )

DNA polymerase I

NC_018520
(Bacillus subtilis QB928)

0.0

255) polA
( YP_007427844.1 )

DNA polymerase I

NC_020244
(Bacillus subtilis XF-1)

0.0

256) I653_13895
( YP_007663534.1 )

DNA polymerase I

NC_020832
(subtilis subtilis BAB-1)

0.0

257) SPSINT_1449
( YP_004149613.1 )

DNA polymerase I

NC_014925
(Staphylococcus pseudintermedius HKU10-03)

0.0

258) BSn5_05375
( YP_004204730.1 )

DNA polymerase I

NC_014976
(Bacillus subtilis BSn5)

0.0

259) A7A1_0772
( YP_007208586.1 )

DNA polymerase I

NC_019896
(Bacillus subtilis BSP1)

0.0

260) Bcoa_2523
( YP_004860481.1 )

DNA polymerase I

NC_016023
(Bacillus coagulans 36D1)

0.0

261) M493_14160
( REF_PRJNA208285:M493 )

DNA polymerase I

NC_022080
(Geobacillus sp. JF8)

0.0

262) LGMK_03120
( YP_004705305.1 )

DNA polymerase I

NC_015734
(Leuconostoc sp. C2)

0.0

263) MY9_2900
( YP_006232689.1 )

hypothetical protein

NC_017743
(Bacillus sp. JS)

0.0

264) polA
( YP_005557883.1 )

DNA polymerase I superfamily

NC_017195
(Bacillus subtilis RO-NN-1)

0.0

265) LKI_08995
( YP_003622307.1 )

DNA-directed DNA polymerase I

NC_014136
(Leuconostoc kimchii IMSNU 11154)

0.0

266) polA
( YP_003867174.1 )

DNA polymerase I

NC_014479
(Bacillus subtilis W23)

0.0

267) polA
( YP_148583.1 )

DNA polymerase I

NC_006510
(Geobacillus kaustophilus HTA426)

0.0

268) polA
( YP_007403073.1 )

DNA polymerase I

NC_020210
(Geobacillus sp. GHH01)

0.0

269) GYMC52_2765
( YP_004133285.1 )

DNA polymerase I

NC_014915
(Geobacillus sp. Y412MC52)

0.0

270) GYMC61_0787
( YP_003251938.1 )

DNA polymerase I

NC_013411
(Geobacillus sp. Y412MC61)

0.0

271) GTCCBUS3UF5_30750
( YP_004983477.1 )

DNA polymerase I

NC_016593
(Geobacillus thermoleovorans CCB_US3_UF5)

0.0

272) polA
( YP_004878393.1 )

DNA polymerase I superfamily

NC_016047
(Bacillus subtilis TU-B-10)

0.0

273) GC56T3_0763
( YP_003670385.1 )

DNA polymerase I

NC_014206
(Geobacillus sp. C56-T3)

0.0

274) polA3
( YP_003921308.1 )

DNA polymerase I

NC_014551
(Bacillus amyloliquefaciens DSM 7)

0.0

275) polA
( YP_005546756.1 )

DNA polymerase I

NC_017190
(Bacillus amyloliquefaciens LL3)

0.0

276) polA
( YP_005542511.1 )

DNA polymerase I

NC_017188
(Bacillus amyloliquefaciens TA208)

0.0

277) BAXH7_02925
( YP_005550897.1 )

DNA polymerase I

NC_017191
(Bacillus amyloliquefaciens XH7)

0.0

278) BCO26_1960
( YP_004569405.1 )

DNA polymerase I

NC_015634
(Bacillus coagulans 2-6)

0.0

279) polA
( YP_008413730.1 )

DNA polymerase I

NC_022075
(Bacillus amyloliquefaciens UCMB-5033)

0.0

280) polA
( YP_008421974.1 )

DNA polymerase I

NC_022081
(Bacillus amyloliquefaciens UCMB5113)

0.0

281) polA
( YP_253149.1 )

DNA polymerase I

NC_007168
(Staphylococcus haemolyticus JCSC1435)

0.0

282) B938_13510
( YP_007187382.1 )

DNA polymerase I

NC_019842
(Bacillus amyloliquefaciens AS43.3)

0.0

283) polA
( YP_007498241.1 )

DNA polymerase I

NC_020410
(Bacillus amyloliquefaciens UCMB5036)

0.0

284) polA
( YP_001422202.1 )

DNA polymerase I

NC_009725
(Bacillus amyloliquefaciens FZB42)

0.0

285) polA
( YP_005131359.1 )

DNA polymerase I

NC_016784
(Bacillus amyloliquefaciens CAU B946)

0.0

286) SLGD_01238
( YP_003471456.1 )

DNA polymerase I

NC_013893
(Staphylococcus lugdunensis HKU09-01)

0.0

287) polA
( YP_005760354.1 )

DNA polymerase I

NC_017353
(Staphylococcus lugdunensis N920143)

0.0

288) KSO_005970
( YP_007444572.1 )

DNA polymerase I

NC_020272
(Bacillus amyloliquefaciens IT-45)

0.0

289) polA
( YP_006329794.1 )

DNA polymerase I

NC_017912
(Bacillus amyloliquefaciens Y2)

0.0

290) polA
( YP_005422165.1 )

DNA polymerase I

NC_017061
(Bacillus amyloliquefaciens YAU B9601-Y2)

0.0

291) C269_03740
( YP_006745077.1 )

DNA polymerase I

NC_018631
(Leuconostoc gelidum JB7)

0.0

292) polA
( YP_006690719.1 )

DNA polymerase I

NC_018590
(Listeria monocytogenes SLCC2376)

0.0

293) polA
( YP_001487771.1 )

DNA polymerase I

NC_009848
(Bacillus pumilus SAFR-032)

0.0

294) B1NLA3E_17130
( YP_007911669.1 )

DNA polymerase I

NC_021171
(Bacillus sp. 1NLA3E)

0.0

295) OEOE_0673
( YP_810275.1 )

DNA polymerase I

NC_008528
(Oenococcus oeni PSU-1)

0.0

296) polA
( YP_006673377.1 )

DNA polymerase I

NC_018584
(Listeria monocytogenes ATCC 19117)

0.0

297) LM220_12122
( YP_008289815.1 )

DNA polymerase I

NC_021830
(Listeria monocytogenes J1-220)

0.0

298) M640_06800
( YP_008301906.1 )

DNA polymerase I

NC_021839
(Listeria monocytogenes J1776)

0.0

299) LM1816_06755
( YP_008287974.1 )

DNA polymerase I

NC_021829
(Listeria monocytogenes J1816)

0.0

300) M644_08125
( YP_008284216.1 )

DNA polymerase I

NC_021827
(Listeria monocytogenes J1817)

0.0

301) M645_07335
( YP_008304897.1 )

DNA polymerase I

NC_021840
(Listeria monocytogenes J1926)

0.0

302) M637_10810
( YP_008275957.1 )

DNA polymerase I

NC_021824
(Listeria monocytogenes J2-064)

0.0

303) M638_10545
( YP_008278748.1 )

DNA polymerase I

NC_021825
(Listeria monocytogenes J2-1091)

0.0

304) polA
( YP_006754694.1 )

DNA polymerase I

NC_018642
(Listeria monocytogenes L312)

0.0

305) polA
( YP_005926614.1 )

DNA polymerase I

NC_017529
(Listeria monocytogenes L99)

0.0

306) polA
( YP_007015155.1 )

DNA polymerase I

NC_019556
(Listeria monocytogenes LL195)

0.0

307) M643_02315
( YP_008280061.1 )

DNA polymerase I

NC_021826
(Listeria monocytogenes N1-011A)

0.0

308) M641_05650
( YP_008298641.1 )

DNA polymerase I

NC_021838
(Listeria monocytogenes R2-502)

0.0

309) polA
( YP_006676252.1 )

DNA polymerase I

NC_018585
(Listeria monocytogenes SLCC2378)

0.0

310) polA
( YP_006693575.1 )

DNA polymerase I

NC_018591
(Listeria monocytogenes SLCC2482)

0.0

311) polA
( YP_006682023.1 )

DNA polymerase I

NC_018587
(Listeria monocytogenes SLCC2755)

0.0

312) MUO_08055
( YP_006205799.1 )

DNA polymerase I

NC_017728
(Listeria monocytogenes 07PF0776)

0.0

313) polA
( YP_002758273.1 )

DNA polymerase I

NC_012488
(Listeria monocytogenes Clip81459)

0.0

314) polA
( YP_014185.1 )

DNA polymerase I

NC_002973
(Listeria monocytogenes F2365)

0.0

315) polA
( YP_002349966.1 )

DNA polymerase I

NC_011660
(Listeria monocytogenes HCC23)

0.0

316) M639_09500
( YP_008296462.1 )

DNA polymerase I

NC_021837
(Listeria monocytogenes J2-031)

0.0

317) polA
( YP_005947714.1 )

DNA polymerase I

NC_017537
(Listeria monocytogenes M7)

0.0

318) polA
( YP_006699232.1 )

DNA polymerase I

NC_018593
(Listeria monocytogenes SLCC7179)

0.0

319) Bsel_1359
( YP_003699437.1 )

DNA polymerase I

NC_014219
(Bacillus selenitireducens MLS10)

0.0

320) polA
( YP_188827.1 )

DNA polymerase I

NC_002976
(Staphylococcus epidermidis RP62A)

0.0

321) WKK_00380
( YP_004725631.1 )

DNA polymerase I

NC_015759
(Weissella koreensis KACC 15510)

0.0

322) M642_05760
( YP_008272015.1 )

DNA polymerase I

NC_021823
(Listeria monocytogenes C1-387)

0.0

323) polA
( YP_006684955.1 )

DNA polymerase I

NC_018588
(Listeria monocytogenes SLCC2372)

0.0

324) polA
( YP_006687890.1 )

DNA polymerase I

NC_018589
(Listeria monocytogenes SLCC2479)

0.0

325) polA
( YP_006679188.1 )

DNA polymerase I

NC_018586
(Listeria monocytogenes SLCC2540)

0.0

326) polA
( YP_003413821.1 )

DNA polymerase I

NC_013766
(Listeria monocytogenes 08-5578)

0.0

327) polA
( YP_003416866.1 )

DNA polymerase I

NC_013768
(Listeria monocytogenes 08-5923)

0.0

328) polA
( NP_465090.1 )

DNA polymerase I

NC_003210
(Listeria monocytogenes EGD-e)

0.0

329) LMLG_1764
( YP_005971376.1 )

DNA polymerase I

NC_017547
(Listeria monocytogenes Finland 1988)

0.0

330) LMKG_00643
( YP_005968532.1 )

DNA polymerase I

NC_017546
(Listeria monocytogenes FSL R2-561)

0.0

331) LMOG_00130
( YP_005965549.1 )

DNA polymerase I

NC_017545
(Listeria monocytogenes J0161)

0.0

332) polA
( NP_470936.1 )

DNA polymerase I

NC_003212
(Listeria innocua Clip11262)

0.0

333) polA
( YP_849775.1 )

DNA polymerase I

NC_008555
(Listeria welshimeri SLCC5334)

0.0

334) polA
( YP_006696456.1 )

DNA polymerase I

NC_018592
(Listeria monocytogenes SLCC5850)

0.0

335) LMRG_01402
( YP_005962681.1 )

DNA polymerase I

NC_017544
(Listeria monocytogenes 10403S)

0.0

336) polA
( YP_002634387.1 )

DNA polymerase I

NC_012121
(Staphylococcus carnosus TM300)

0.0

337) SSP1075
( YP_301165.1 )

DNA polymerase I

NC_007350
(Staphylococcus saprophyticus ATCC 15305)

0.0

338) MI1_03255
( YP_005174077.1 )

DNA polymerase I

NC_016805
(Leuconostoc mesenteroides J18)

0.0

339) LEUM_0713
( YP_818196.1 )

DNA polymerase I

NC_008531
(Leuconostoc mesenteroides ATCC 8293)

0.0

340) SE1367
( NP_764922.1 )

DNA polymerase I

NC_004461
(Staphylococcus epidermidis ATCC 12228)

0.0

341) polA
( YP_002560760.1 )

DNA polymerase I

NC_011999
(Macrococcus caseolyticus JCSC5402)

0.0

342) EAT1b_0662
( YP_002885038.1 )

DNA polymerase I

NC_012673
(Exiguobacterium sp. AT1b)

0.0

343) polA
( YP_006237943.1 )

DNA polymerase I

NC_017763
(Staphylococcus aureus HO 5096 0412)

0.0

344) polA
( YP_417019.1 )

DNA polymerase I

NC_007622
(Staphylococcus aureus RF122)

0.0

345) SAOV_1678
( YP_005737164.1 )

DNA polymerase I

NC_017337
(Staphylococcus aureus ED133)

0.0

346) polA
( YP_005755566.1 )

DNA polymerase I

NC_017349
(Staphylococcus aureus LGA251)

0.0

347) polA
( YP_008485565.1 )

DNA polymerase I

NC_022222
(Staphylococcus aureus 6850)

0.0

348) M013TW_1703
( YP_005298128.1 )

DNA polymerase I

NC_016928
(Staphylococcus aureus M013)

0.0

349) polA
( YP_008588194.1 )

DNA polymerase I

NC_022443
(Staphylococcus aureus SA40)

0.0

350) polA
( YP_008585729.1 )

DNA polymerase I

NC_022442
(Staphylococcus aureus SA957)

0.0

351) Bcell_3214
( YP_004096187.1 )

DNA polymerase I

NC_014829
(Bacillus cellulosilyticus DSM 2522)

0.0

352) polA
( YP_008128540.1 )

DNA polymerase I

NC_021554
(Staphylococcus aureus CA-347)

0.0

353) polA
( YP_041156.1 )

DNA polymerase I

NC_002952
(Staphylococcus aureus MRSA252)

0.0

354) polA
( YP_008079219.1 )

DNA polymerase I

NC_021362
(Bacillus licheniformis 9945A)

0.0

355) polA
( YP_008168839.1 )

DNA polymerase I

NC_021670
(Staphylococcus aureus Bmb9393)

0.0

356) polA
( YP_005742398.1 )

DNA polymerase I

NC_017340
(Staphylococcus aureus 04-02981)

0.0

357) polA
( YP_005758136.1 )

DNA polymerase I

NC_017351
(Staphylococcus aureus 11819-97)

0.0

358) SAAG_01594
( YP_008449599.1 )

DNA polymerase I

NC_022113
(Staphylococcus aureus 55/2053)

0.0

359) polA
( YP_005750260.1 )

DNA polymerase I

NC_017343
(Staphylococcus aureus ECT-R 2)

0.0

360) polA
( YP_003282577.1 )

DNA polymerase I

NC_013450
(Staphylococcus aureus ED98)

0.0

361) SaurJH1_1781
( YP_001316912.1 )

DNA polymerase I

NC_009632
(Staphylococcus aureus JH1)

0.0

362) SaurJH9_1747
( YP_001247113.1 )

DNA polymerase I

NC_009487
(Staphylococcus aureus JH9)

0.0

363) polA
( YP_001442266.1 )

DNA polymerase I

NC_009782
(Staphylococcus aureus Mu3)

0.0

364) polA
( NP_372214.1 )

DNA polymerase I

NC_002758
(Staphylococcus aureus Mu50)

0.0

365) polA
( NP_374801.1 )

DNA polymerase I

NC_002745
(Staphylococcus aureus N315)

0.0

366) polA
( YP_007583819.1 )

DNA polymerase

NC_020536
(Staphylococcus aureus ST228)

0.0

367) polA
( YP_007621533.1 )

DNA polymerase

NC_020566
(Staphylococcus aureus ST228)

0.0

368) polA
( YP_007623522.1 )

DNA polymerase

NC_020568
(Staphylococcus aureus ST228)

0.0

369) polA
( YP_007577832.1 )

DNA polymerase

NC_020529
(Staphylococcus aureus ST228 (isolate=10388))

0.0

370) polA
( YP_007619549.1 )

DNA polymerase

NC_020564
(Staphylococcus aureus ST228 (isolate=10497))

0.0

371) polA
( YP_007579840.1 )

DNA polymerase

NC_020532
(Staphylococcus aureus ST228 (isolate=15532))

0.0

372) polA
( YP_007581805.1 )

DNA polymerase

NC_020533
(Staphylococcus aureus ST228 (isolate=16035))

0.0

373) polA
( YP_007585786.1 )

DNA polymerase

NC_020537
(Staphylococcus aureus ST228 (isolate=18412))

0.0

374) polA
( YP_006710470.1 )

DNA polymerase I

NC_018608
(Staphylococcus aureus 08BA02176)

0.0

375) ST398NM01_1744
( YP_006195763.1 )

DNA polymerase I

NC_017673
(Staphylococcus aureus 71193)

0.0

376) polA
( YP_186574.1 )

DNA polymerase I

NC_002951
(Staphylococcus aureus COL)

0.0

377) polA
( YP_494331.1 )

DNA polymerase I superfamily protein

NC_007793
(Staphylococcus aureus FPR3757)

0.0

378) polA
( YP_005745007.1 )

DNA-directed DNA polymerase I

NC_017341
(Staphylococcus aureus JKD6008)

0.0

379) BN843_16900
( YP_007868755.1 )

DNA polymerase I

NC_021059
(Staphylococcus aureus M1)

0.0

380) SAS1618
( YP_043737.1 )

DNA polymerase I

NC_002953
(Staphylococcus aureus MSSA476)

0.0

381) polA
( NP_646450.1 )

DNA polymerase I

NC_003923
(Staphylococcus aureus MW2)

0.0

382) SAOUHSC_01797
( YP_500301.1 )

DNA polymerase I

NC_007795
(Staphylococcus aureus NCTC 8325)

0.0

383) polA
( YP_001332617.1 )

DNA polymerase I

NC_009641
(Staphylococcus aureus Newman)

0.0

384) SAT0131_01792
( YP_005752941.1 )

DNA polymerase I

NC_017347
(Staphylococcus aureus T0131)

0.0

385) polA
( YP_001575563.1 )

DNA polymerase I

NC_010079
(Staphylococcus aureus TCH1516)

0.0

386) polA
( YP_005731680.1 )

DNA polymerase I

NC_017331
(Staphylococcus aureus TW20)

0.0

387) SAVC_07655
( YP_005291124.1 )

DNA polymerase I

NC_016912
(Staphylococcus aureus VC40)

0.0

388) SAPIG1744
( YP_005734540.1 )

DNA polymerase I (POL I)

NC_017333
(Staphylococcus aureus ST398)

0.0

389) SAA6159_01614
( YP_005739758.1 )

DNA-directed DNA polymerase I

NC_017338
(Staphylococcus aureus JKD6159)

0.0

390) polA
( YP_005747543.1 )

DNA-directed DNA polymerase I

NC_017342
(Staphylococcus aureus TCH60)

0.0

391) SAKOR_01630
( YP_008491818.1 )

DNA polymerase I

NC_022226
(Staphylococcus aureus CN1)

0.0

392) polA
( YP_004855276.1 )

putative DNA polymerase I

NC_016011
(Listeria ivanovii PAM 55)

0.0

393) polA
( YP_003464717.1 )

DNA polymerase I

NC_013891
(Listeria seeligeri SLCC3954)

0.0

394) polA
( YP_176205.1 )

DNA polymerase I

NC_006582
(Bacillus clausii KSM-K16)

0.0

395) polA
( YP_006714393.1 )

DNA polymerase I

NC_006322
(Bacillus licheniformis DSM 13)

0.0

396) polA
( YP_080201.1 )

DNA polymerase I

NC_006270
(Bacillus licheniformis DSM 13)

0.0

397) polA
( YP_002770886.1 )

DNA polymerase I

NC_012491
(Brevibacillus brevis NBRC 100599)

0.0

398) HPL003_16285
( YP_005076226.1 )

DNA polymerase i

NC_016641
(Paenibacillus terrae HPL-003)

0.0

399) GYMC10_4912
( YP_003244933.1 )

DNA polymerase I

NC_013406
(Paenibacillus sp. Y412MC10)

0.0

400) SAMSHR1132_15210
( YP_005326035.1 )

DNA polymerase I

NC_016941
(Staphylococcus aureus MSHR1132)

0.0

401) polA
( YP_005959228.1 )

DNA polymerase I

NC_017542
(Paenibacillus polymyxa M1)

0.0

402) PPSC2_c1766
( YP_003945981.1 )

DNA polymerase i

NC_014622
(Paenibacillus polymyxa SC2)

0.0

403) PPE_01596
( YP_003869973.1 )

DNA polymerase I

NC_014483
(Paenibacillus polymyxa E681)

0.0

404) Exig_2202
( YP_001814671.1 )

DNA polymerase I

NC_010556
(Exiguobacterium sibiricum 255-15)

0.0

405) polA
( YP_006181372.1 )

DNA polymerase I

NC_017668
(Halobacillus halophilus DSM 2266)

0.0

406) polA
( YP_006791759.1 )

DNA polymerase I

NC_018665
(Exiguobacterium antarcticum Eab7)

0.0

407) BATR1942_12330
( YP_003974328.1 )

DNA polymerase I

NC_014639
(Bacillus atrophaeus 1942)

0.0

408) polA
( YP_003425624.1 )

DNA polymerase I

NC_013791
(Bacillus pseudofirmus OF4)

0.0

409) Aaci_2345
( YP_003185741.1 )

DNA polymerase I

NC_013205
(Alicyclobacillus acidocaldarius DSM 446)

0.0

410) polA
( YP_005519042.1 )

DNA polymerase I

NC_017167
(Alicyclobacillus acidocaldarius Tc-4-1)

0.0

411) Pjdr2_1523
( YP_003010281.1 )

DNA polymerase I

NC_012914
(Paenibacillus sp. JDR-2)

3e-178

412) polA
( YP_006787851.1 )

DNA polymerase I

NC_018664
(Clostridium acidurici 9a)

2e-171

413) TherJR_0963
( YP_003639730.1 )

DNA polymerase I

NC_014152
(Thermincola potens JR)

4e-170

414) Apre_1330
( YP_003153074.1 )

DNA polymerase I

NC_013171
(Anaerococcus prevotii DSM 20548)

9e-170

415) polA-2
( YP_005675860.1 )

DNA polymerase I

NC_017297
(Clostridium botulinum 230613)

3e-169

416) polA-2
( YP_001392289.1 )

DNA polymerase I

NC_009699
(Clostridium botulinum Langeland)

3e-169

417) polA
( YP_001394071.1 )

DNA polymerase I

NC_009706
(Clostridium kluyveri DSM 555)

2e-168

418) CKR_0594
( YP_002471059.1 )

DNA polymerase I

NC_011837
(Clostridium kluyveri NBRC 12016)

2e-168

419) polA
( YP_001782645.1 )

DNA polymerase I

NC_010516
(Clostridium botulinum Okra)

6e-168

420) CbC4_0864
( YP_004395541.1 )

DNA polymerase I

NC_015425
(Clostridium botulinum BKT015925)

4e-167

421) Mahau_1179
( YP_004463198.1 )

DNA polymerase I

NC_015520
(Mahella australiensis 50-1 BON)

5e-166

422) polA
( YP_001385333.1 )

DNA polymerase I

NC_009697
(Clostridium botulinum ATCC 19397)

7e-166

423) polA
( YP_001255504.1 )

DNA polymerase I

NC_009495
(Clostridium botulinum ATCC 3502)

7e-166

424) polA
( YP_001388741.1 )

DNA polymerase I

NC_009698
(Clostridium botulinum Hall)

7e-166

425) H04402_03109
( YP_005679641.1 )

DNA polymerase I

NC_017299
(Clostridium botulinum H04402 065)

1e-165

426) polA
( YP_002805528.1 )

DNA polymerase I

NC_012563
(Clostridium botulinum Kyoto)

2e-165

427) polA
( YP_002864017.1 )

DNA polymerase I

NC_012658
(Clostridium botulinum 657)

4e-165

428) polA
( YP_001788325.1 )

DNA polymerase I

NC_010520
(Clostridium botulinum Loch Maree)

2e-164

429) Desku_0593
( YP_004516008.1 )

DNA polymerase I

NC_015573
(Desulfotomaculum kuznetsovii DSM 6115)

6e-163

430) CTC02103
( NP_782664.1 )

DNA polymerase I

NC_004557
(Clostridium tetani E88)

2e-162

431) Moth_1841
( YP_430684.1 )

DNA polymerase I

NC_007644
(Moorella thermoacetica ATCC 39073)

7e-162

432) polA
( YP_007372572.1 )

DNA polymerase I

NC_020134
(Clostridium stercorarium DSM 8532)

8e-162

433) Clst_0924
( YP_007679016.1 )

DNA polymerase-1

NC_020887
(Clostridium stercorarium DSM 8532)

8e-162

434) FMG_0343
( YP_001691651.1 )

DNA polymerase I

NC_010376
(Finegoldia magna ATCC 29328)

2e-161

435) Clocl_2645
( YP_005047135.1 )

DNA polymerase I

NC_016627
(Clostridium clariflavum DSM 19732)

4e-161

436) Toce_1653
( YP_003826013.1 )

DNA polymerase I

NC_014377
(Thermosediminibacter oceani DSM 16646)

1e-160

437) PolA
( NP_622526.1 )

DNA polymerase I

NC_003869
(Thermoanaerobacter tengcongensis MB4)

2e-160

438) Thexy_1599
( YP_004471302.1 )

DNA polymerase I

NC_015555
(Thermoanaerobacterium xylanolyticum LX-11)

4e-160

439) NT01CX_1677
( YP_877757.1 )

DNA polymerase I

NC_008593
(Clostridium novyi NT)

7e-160

440) Desca_1026
( YP_004496809.1 )

DNA polymerase I

NC_015565
(Desulfotomaculum carboxydivorans CO-1-SRB)

1e-159

441) polA
( YP_003781508.1 )

DNA polymerase I

NC_014328
(Clostridium ljungdahlii ATCC 49587)

2e-159

442) Desru_2499
( YP_004546016.1 )

DNA polymerase I

NC_015589
(Desulfotomaculum ruminis DSM 2154)

2e-159

443) polA
( YP_006920508.1 )

DNA polymerase I

NC_018870
(Thermacetogenium phaeum DSM 12270)

2e-159

444) polA
( YP_001620348.1 )

DNA polymerase I

NC_010163
(Acholeplasma laidlawii PG-8A)

4e-159

445) Tsac_2145
( YP_006392748.1 )

DNA polymerase I

NC_017992
(Thermoanaerobacterium saccharolyticum JW/SL-YS485)

8e-159

446) TepRe1_1612
( YP_004461058.1 )

DNA polymerase I

NC_015519
(Tepidanaerobacter acetatoxydans Re1)

6e-157

447) polA
( YP_008619037.1 )

DNA polymerase I

NC_019954
(Tepidanaerobacter acetatoxydans Re1)

6e-157

448) Dred_1599
( YP_001112952.1 )

DNA polymerase I

NC_009253
(Desulfotomaculum reducens MI-1)

2e-155

449) STH848
( YP_074677.1 )

DNA polymerase I

NC_006177
(Symbiobacterium thermophilum IAM 14863)

3e-155

450) polA
( YP_696673.1 )

DNA polymerase I

NC_008261
(Clostridium perfringens ATCC 13124)

4e-155

451) Hore_04860
( YP_002508239.1 )

DNA polymerase I

NC_011899
(Halothermothrix orenii H 168)

8e-155

452) polA
( NP_562910.1 )

DNA polymerase I

NC_003366
(Clostridium perfringens 13)

9e-155

453) polA
( YP_699271.1 )

DNA polymerase I

NC_008262
(Clostridium perfringens SM101)

2e-154

454) Dtox_2415
( YP_003191849.1 )

DNA polymerase I

NC_013216
(Desulfotomaculum acetoxidans DSM 771)

8e-154

455) MMALV_07150
( YP_007713378.1 )

DNA polymerase I

NC_020913
(Candidatus Methanomethylophilus alvus Mx1201)

2e-153

456) polA
( YP_003936432.1 )

DNA polymerase I

NC_014614
(Clostridium sticklandii DSM 519)

3e-153

457) Clopa_2063
( YP_007940626.1 )

DNA polymerase I

NC_021182
(Clostridium pasteurianum BC1)

6e-153

458) polA
( YP_005433236.1 )

putative DNA polymerase I

NC_017068
(Selenomonas ruminantium TAM6421)

7e-153

459) polA
( YP_008027093.1 )

DNA polymerase I

NC_021284
(Spiroplasma syrphidicola EA-1)

1e-151

460) polA
( YP_003174431.1 )

DNA polymerase I

NC_013199
(Lactobacillus rhamnosus Lc 705)

7e-152

461) Halha_0427
( YP_007314513.1 )

DNA polymerase I

NC_019978
(Halobacteroides halobius DSM 5150)

1e-151

462) Cbei_0801
( YP_001307941.1 )

DNA polymerase I

NC_009617
(Clostridium beijerinckii NCIMB 8052)

2e-151

463) HMPREF0389_00606
( YP_005054746.1 )

DNA polymerase I

NC_016630
(Filifactor alocis ATCC 35896)

8e-151

464) polA
( YP_008018339.1 )

DNA polymerase I

NC_021280
(Spiroplasma chrysopicola DF-1)

6e-150

465) polA
( NP_347732.1 )

DNA polymerase I

NC_003030
(Clostridium acetobutylicum ATCC 824)

7e-150

466) polA
( YP_004635762.1 )

DNA polymerase I

NC_015687
(Clostridium acetobutylicum DSM 1731)

7e-150

467) polA
( YP_005670242.1 )

DNA polymerase I

NC_017295
(Clostridium acetobutylicum EA 2018)

7e-150

468) Clos_1206
( YP_001512748.1 )

DNA polymerase I

NC_009922
(Alkaliphilus oremlandii OhILAs)

1e-149

469) Slip_1695
( YP_003703018.1 )

DNA polymerase I

NC_014220
(Syntrophothermus lipocalidus DSM 12680)

1e-149

470) Daud_1403
( YP_001717544.1 )

DNA polymerase I

NC_010424
(Candidatus Desulforudis audaxviator MP104C)

1e-149

471) Swol_2017
( YP_754683.1 )

DNA polymerase I

NC_008346
(Syntrophomonas wolfei Goettingen)

1e-148

472) Clocel_2730
( YP_003844191.1 )

DNA polymerase I

NC_014393
(Clostridium cellulovorans 743B)

2e-148

473) Desde_1951
( YP_006430132.1 )

DNA polymerase I

NC_018017
(Desulfitobacterium dehalogenans ATCC 51507)

2e-148

474) Amet_3125
( YP_001320923.1 )

DNA polymerase I

NC_009633
(Alkaliphilus metalliredigens QYMF)

2e-148

475) Clole_2063
( YP_004308975.1 )

DNA polymerase I

NC_015275
(Clostridium lentocellum DSM 5427)

1e-147

476) Thit_0811
( YP_003476651.1 )

DNA polymerase I

NC_013921
(Thermoanaerobacter italicus Ab9)

1e-147

477) Tmath_0850
( YP_003676598.1 )

DNA polymerase I

NC_014209
(Thermoanaerobacter mathranii A3)

1e-147

478) Acear_0340
( YP_003826952.1 )

DNA polymerase I

NC_014378
(Acetohalobium arabaticum DSM 5501)

9e-148

479) polA
( YP_007453912.1 )

DNA polymerase I

NC_020291
(Clostridium saccharoperbutylacetonicum N1-4(HMT))

2e-147

480) Desdi_1602
( YP_007220490.1 )

DNA polymerase I

NC_019903
(Desulfitobacterium dichloroeliminans LMG P-21439)

1e-146

481) Clo1100_2472
( YP_005148446.1 )

DNA polymerase I

NC_016791
(Clostridium sp. BNL1100)

2e-146

482) CC1_18790
( YP_007770023.1 )

DNA polymerase I

NC_021009
(Coprococcus catus GD/7)

5e-146

483) Tthe_1101
( YP_003851706.1 )

DNA polymerase I

NC_014410
(Thermoanaerobacterium thermosaccharolyticum DSM 571)

5e-145

484) Thet_0779
( YP_003903700.1 )

DNA polymerase I

NC_014538
(Thermoanaerobacter sp. X513)

1e-144

485) Teth514_2156
( YP_001663764.1 )

DNA polymerase I

NC_010320
(Thermoanaerobacter sp. X514)

1e-144

486) polA
( YP_360471.1 )

DNA polymerase I

NC_007503
(Carboxydothermus hydrogenoformans Z-2901)

8e-143

487) Cthe_0886
( YP_001037313.1 )

DNA polymerase I

NC_009012
(Clostridium thermocellum ATCC 27405)

8e-142

488) Clo1313_1334
( YP_005687848.1 )

DNA polymerase I

NC_017304
(Clostridium thermocellum DSM 1313)

8e-142

489) polA
( YP_004897432.1 )

DNA polymerase I

NC_016077
(Acidaminococcus intestini RyC-MR95)

9e-142

490) SFBM_0266
( YP_004770787.1 )

DNA polymerase I

NC_015913
(Candidatus Arthromitus sp. mouse isolate)

4e-141

491) polA2
( YP_005667960.1 )

DNA polymerase I

NC_017294
(Candidatus Arthromitus sp. SFB-mouse-Yit)

4e-141

492) Ccel_2075
( YP_002506400.1 )

DNA polymerase I

NC_011898
(Clostridium cellulolyticum H10)

3e-140

493) Calow_1220
( YP_004002578.1 )

DNA polymerase i

NC_014657
(Caldicellulosiruptor owensensis OL)

2e-139

494) polA
( YP_005269800.1 )

DNA polymerase I

NC_016894
(Acetobacterium woodii DSM 1030)

3e-138

495) polA
( YP_003214017.1 )

DNA polymerase I

NC_013315
(Clostridium difficile CD196)

7e-137

496) polA
( YP_003217463.1 )

DNA polymerase I

NC_013316
(Clostridium difficile R20291)

7e-137

497) Adeg_1024
( YP_003239007.1 )

DNA polymerase I

NC_013385
(Ammonifex degensii KC4)

9e-135

498) COB47_1113
( YP_003840398.1 )

DNA polymerase I

NC_014392
(Caldicellulosiruptor obsidiansis OB47)

2e-132

499) EC1_00380
( YP_007797452.1 )

DNA polymerase I

NC_021019
(Eubacterium cylindroides T2-87)

8e-126

• Sequence Alignments

1) polA in NC_018936


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score = 1427 bits (5418),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 880/880 (100%), Positives = 880/880 (100%), Gaps = 0/880 (0%)

Query  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60
            MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV
Sbjct  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60

Query  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120
            LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII
Sbjct  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120

Query  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180
            GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT
Sbjct  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180

Query  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240
            PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQE  300
            DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQE
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQE  300

Query  301  PVAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLAT  360
            PVAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLAT
Sbjct  301  PVAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLAT  360

Query  361  DSFKQVFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIFT  420
            DSFKQVFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIFT
Sbjct  361  DSFKQVFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIFT  420

Query  421  DISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNIE  480
            DISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNIE
Sbjct  421  DISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNIE  480

Query  481  LPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSIL  540
            LPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSIL
Sbjct  481  LPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSIL  540

Query  541  FEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYIL  600
            FEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYIL
Sbjct  541  FEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYIL  600

Query  601  ADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQI  660
            ADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQI
Sbjct  601  ADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQI  660

Query  661  ELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGI  720
            ELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGI
Sbjct  661  ELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGI  720

Query  721  SDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDI  780
            SDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDI
Sbjct  721  SDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDI  780

Query  781  NSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEV  840
            NSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEV
Sbjct  781  NSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEV  840

Query  841  PNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880
            PNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK
Sbjct  841  PNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

2) polA in NC_020540


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score = 1427 bits (5418),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 880/880 (100%), Positives = 880/880 (100%), Gaps = 0/880 (0%)

Query  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60
            MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV
Sbjct  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60

Query  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120
            LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII
Sbjct  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120

Query  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180
            GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT
Sbjct  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180

Query  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240
            PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQE  300
            DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQE
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQE  300

Query  301  PVAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLAT  360
            PVAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLAT
Sbjct  301  PVAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLAT  360

Query  361  DSFKQVFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIFT  420
            DSFKQVFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIFT
Sbjct  361  DSFKQVFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIFT  420

Query  421  DISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNIE  480
            DISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNIE
Sbjct  421  DISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNIE  480

Query  481  LPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSIL  540
            LPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSIL
Sbjct  481  LPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSIL  540

Query  541  FEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYIL  600
            FEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYIL
Sbjct  541  FEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYIL  600

Query  601  ADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQI  660
            ADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQI
Sbjct  601  ADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQI  660

Query  661  ELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGI  720
            ELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGI
Sbjct  661  ELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGI  720

Query  721  SDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDI  780
            SDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDI
Sbjct  721  SDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDI  780

Query  781  NSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEV  840
            NSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEV
Sbjct  781  NSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEV  840

Query  841  PNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880
            PNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK
Sbjct  841  PNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

3) polA in NC_007297


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score = 1427 bits (5418),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 880/880 (100%), Positives = 880/880 (100%), Gaps = 0/880 (0%)

Query  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60
            MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV
Sbjct  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60

Query  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120
            LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII
Sbjct  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120

Query  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180
            GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT
Sbjct  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180

Query  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240
            PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQE  300
            DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQE
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQE  300

Query  301  PVAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLAT  360
            PVAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLAT
Sbjct  301  PVAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLAT  360

Query  361  DSFKQVFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIFT  420
            DSFKQVFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIFT
Sbjct  361  DSFKQVFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIFT  420

Query  421  DISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNIE  480
            DISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNIE
Sbjct  421  DISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNIE  480

Query  481  LPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSIL  540
            LPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSIL
Sbjct  481  LPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSIL  540

Query  541  FEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYIL  600
            FEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYIL
Sbjct  541  FEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYIL  600

Query  601  ADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQI  660
            ADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQI
Sbjct  601  ADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQI  660

Query  661  ELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGI  720
            ELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGI
Sbjct  661  ELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGI  720

Query  721  SDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDI  780
            SDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDI
Sbjct  721  SDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDI  780

Query  781  NSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEV  840
            NSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEV
Sbjct  781  NSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEV  840

Query  841  PNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880
            PNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK
Sbjct  841  PNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

4) polA in NC_008021


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score = 1427 bits (5418),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 880/880 (100%), Positives = 880/880 (100%), Gaps = 0/880 (0%)

Query  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60
            MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV
Sbjct  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60

Query  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120
            LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII
Sbjct  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120

Query  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180
            GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT
Sbjct  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180

Query  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240
            PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQE  300
            DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQE
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQE  300

Query  301  PVAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLAT  360
            PVAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLAT
Sbjct  301  PVAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLAT  360

Query  361  DSFKQVFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIFT  420
            DSFKQVFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIFT
Sbjct  361  DSFKQVFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIFT  420

Query  421  DISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNIE  480
            DISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNIE
Sbjct  421  DISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNIE  480

Query  481  LPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSIL  540
            LPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSIL
Sbjct  481  LPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSIL  540

Query  541  FEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYIL  600
            FEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYIL
Sbjct  541  FEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYIL  600

Query  601  ADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQI  660
            ADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQI
Sbjct  601  ADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQI  660

Query  661  ELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGI  720
            ELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGI
Sbjct  661  ELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGI  720

Query  721  SDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDI  780
            SDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDI
Sbjct  721  SDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDI  780

Query  781  NSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEV  840
            NSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEV
Sbjct  781  NSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEV  840

Query  841  PNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880
            PNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK
Sbjct  841  PNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

5) pol in NC_009332


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score = 1425 bits (5408),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 876/880 (99%), Positives = 879/880 (99%), Gaps = 0/880 (0%)

Query  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60
            MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV
Sbjct  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60

Query  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFPYIREMLTALGIAYYELEHYEADDII  120
            LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQF+YIREMLTALGIAYYELEHYEADDII
Sbjct  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120

Query  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180
            GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT
Sbjct  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180

Query  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKASKMKENLIN  240
            PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFK+SKMKENLIN
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQE  300
            DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQE
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQE  300

Query  301  PVAAISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLAT  360
            PVA ISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLAT
Sbjct  301  PVAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLAT  360

Query  361  DSFKQVFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIFT  420
            DSFKQVFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIFT
Sbjct  361  DSFKQVFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIFT  420

Query  421  DISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNIE  480
            DISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNIE
Sbjct  421  DISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNIE  480

Query  481  LPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSIL  540
            LPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSIL
Sbjct  481  LPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSIL  540

Query  541  FEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYIL  600
            FEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYIL
Sbjct  541  FEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYIL  600

Query  601  ADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQI  660
            ADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQI
Sbjct  601  ADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQI  660

Query  661  ELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGI  720
            ELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGI
Sbjct  661  ELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGI  720

Query  721  SDFGLSNNLGITRKQAKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDI  780
            SDFGLSNNLGITRKQ+KSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDI
Sbjct  721  SDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDI  780

Query  781  NSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEV  840
            NSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEV
Sbjct  781  NSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEV  840

Query  841  PNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880
            PNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK
Sbjct  841  PNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

6) spyM18_0184 in NC_003485


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score = 1424 bits (5405),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 875/880 (99%), Positives = 879/880 (99%), Gaps = 0/880 (0%)

Query  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60
            MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV
Sbjct  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60

Query  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFPYIREMLTALGIAYYELEHYEADDII  120
            LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQF+YIREMLTALGIAYYELEHYEADDII
Sbjct  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120

Query  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180
            GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT
Sbjct  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180

Query  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKASKMKENLIN  240
            PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFK+SKMKENLIN
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQE  300
            DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQE
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQE  300

Query  301  PVAAISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLAT  360
            PVA ISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLAT
Sbjct  301  PVAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLAT  360

Query  361  DSFKQVFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIFT  420
            DSFKQVFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIFT
Sbjct  361  DSFKQVFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIFT  420

Query  421  DISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNIE  480
            DISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNIE
Sbjct  421  DISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNIE  480

Query  481  LPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSIL  540
            LPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSIL
Sbjct  481  LPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSIL  540

Query  541  FEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYIL  600
            FEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYIL
Sbjct  541  FEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYIL  600

Query  601  ADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLGSDYSQI  660
            ADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLL+SDYSQI
Sbjct  601  ADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQI  660

Query  661  ELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGI  720
            ELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGI
Sbjct  661  ELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGI  720

Query  721  SDFGLSNNLGITRKQAKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDI  780
            SDFGLSNNLGITRKQ+KSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDI
Sbjct  721  SDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDI  780

Query  781  NSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEV  840
            NSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEV
Sbjct  781  NSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEV  840

Query  841  PNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880
            PNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK
Sbjct  841  PNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

7) L897_01030 in NC_021807


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score = 1423 bits (5400),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 873/880 (99%), Positives = 879/880 (99%), Gaps = 0/880 (0%)

Query  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVQPTHV  60
            MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRV+PTHV
Sbjct  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60

Query  61   LVAFDAGKTTFRTEMYADYKAGRAKTPEEFREQFPYIREMLTALGIAYYELEHYEADDII  120
            LVAFDAGKTTFRTEMYADYKAGRAKTP+EFREQF+YIREMLTALGIAYYELEHYEADDII
Sbjct  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120

Query  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180
            GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT
Sbjct  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180

Query  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKASKMKENLIN  240
            PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFK+SKMKENLIN
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQE  300
            DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQE
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQE  300

Query  301  PVAAISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLGLLAT  360
            PVA ISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDL+LLAT
Sbjct  301  PVAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLAT  360

Query  361  DSFKQVFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIFT  420
            DSFKQVFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIFT
Sbjct  361  DSFKQVFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIFT  420

Query  421  DISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNIE  480
            DISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNIE
Sbjct  421  DISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNIE  480

Query  481  LPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSIL  540
            LPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSIL
Sbjct  481  LPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSIL  540

Query  541  FEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYIL  600
            FEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYIL
Sbjct  541  FEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYIL  600

Query  601  ADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQI  660
            ADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQI
Sbjct  601  ADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQI  660

Query  661  ELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGI  720
            ELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGI
Sbjct  661  ELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGI  720

Query  721  SDFGLSNNLGITRKQAKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDI  780
            SDFGLSNNLGITRKQ+KSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDI
Sbjct  721  SDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDI  780

Query  781  NSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEV  840
            NSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEV
Sbjct  781  NSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEV  840

Query  841  PNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880
            PNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK
Sbjct  841  PNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

8) polA in NC_002737


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score = 1422 bits (5397),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 872/880 (99%), Positives = 880/880 (100%), Gaps = 0/880 (0%)

Query  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVQPTHV  60
            MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRV+PTHV
Sbjct  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60

Query  61   LVAFDAGKTTFRTEMYADYKAGRAKTPEEFREQFPYIREMLTALGIAYYELEHYEADDII  120
            LVAFDAGKTTFRTEMYADYKAGRAKTP+EFREQF+YIREMLTALGIAYYELEHYEADDII
Sbjct  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120

Query  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180
            GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT
Sbjct  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180

Query  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240
            PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQE  300
            DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQE
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQE  300

Query  301  PVAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLGLLAT  360
            PVAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDL+LLAT
Sbjct  301  PVAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLAT  360

Query  361  DSFKQVFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIFT  420
            DSFKQVFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIFT
Sbjct  361  DSFKQVFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIFT  420

Query  421  DISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNIE  480
            DISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNIE
Sbjct  421  DISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNIE  480

Query  481  LPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSIL  540
            LPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSIL
Sbjct  481  LPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSIL  540

Query  541  FEKMQLPLEMTKKTKTGYSTAVNVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYIL  600
            FEKMQLPLEMTKKTKTGYSTAV+VLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYIL
Sbjct  541  FEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYIL  600

Query  601  ADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQI  660
            ADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQI
Sbjct  601  ADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQI  660

Query  661  ELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDRAADVTANDRRNAKAVNFGIVYGI  720
            ELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGID+AADVTANDRRNAKAVNFGIVYGI
Sbjct  661  ELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGI  720

Query  721  SDFGLSNNLGITRKQAKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDI  780
            SDFGLSNNLGITRKQ+KSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDI
Sbjct  721  SDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDI  780

Query  781  NSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEV  840
            NSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEV
Sbjct  781  NSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEV  840

Query  841  PNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGHSWYEAK  880
            PNDELTAIKKLVKDTMEAAVDLAVPLCVDESTG+SWYEAK
Sbjct  841  PNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

9) polA in NC_008022


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score = 1422 bits (5399),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 874/880 (99%), Positives = 879/880 (99%), Gaps = 0/880 (0%)

Query  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVQPTHV  60
            MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRV+PTHV
Sbjct  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60

Query  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFPYIREMLTALGIAYYELEHYEADDII  120
            LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQF+YIREMLTALGIAYYELEHYEADDII
Sbjct  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120

Query  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180
            GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT
Sbjct  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180

Query  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKASKMKENLIN  240
            PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFK+SKMKENLIN
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQE  300
            DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQE
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQE  300

Query  301  PVAAISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLGLLAT  360
            PVA ISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDL+LLAT
Sbjct  301  PVAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLAT  360

Query  361  DSFKQVFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIFT  420
            DSFKQVFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIFT
Sbjct  361  DSFKQVFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIFT  420

Query  421  DISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNIE  480
            DISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNIE
Sbjct  421  DISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNIE  480

Query  481  LPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSIL  540
            LPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSIL
Sbjct  481  LPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSIL  540

Query  541  FEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYIL  600
            FEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYIL
Sbjct  541  FEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYIL  600

Query  601  ADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQI  660
            ADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQI
Sbjct  601  ADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQI  660

Query  661  ELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGI  720
            ELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGI
Sbjct  661  ELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGI  720

Query  721  SDFGLSNNLGITRKQAKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDI  780
            SDFGLSNNLGITRKQ+KSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDI
Sbjct  721  SDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDI  780

Query  781  NSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEV  840
            NSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEV
Sbjct  781  NSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEV  840

Query  841  PNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880
            PNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK
Sbjct  841  PNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

10) polA in NC_017596


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score = 1421 bits (5393),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 872/880 (99%), Positives = 878/880 (99%), Gaps = 0/880 (0%)

Query  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVQPTHV  60
            MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRV+PTHV
Sbjct  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60

Query  61   LVAFDAGKTTFRTEMYADYKAGRAKTPEEFREQFPYIREMLTALGIAYYELEHYEADDII  120
            LVAFDAGKTTFRTEMYADYKAGRAKTP+EFREQF+YIREMLTALGIAYYELEHYEADDII
Sbjct  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120

Query  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180
            GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT
Sbjct  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180

Query  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKASKMKENLIN  240
            PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFK+SKMKENLIN
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQE  300
            DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQE
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQE  300

Query  301  PVAAISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLGLLAT  360
            PVA ISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDL+LLAT
Sbjct  301  PVAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLAT  360

Query  361  DSFKQVFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIFT  420
            DSFKQVFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIFT
Sbjct  361  DSFKQVFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIFT  420

Query  421  DISLEEDDIVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNIE  480
            DISLEEDD VYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNIE
Sbjct  421  DISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNIE  480

Query  481  LPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSIL  540
            LPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSIL
Sbjct  481  LPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSIL  540

Query  541  FEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYIL  600
            FEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYIL
Sbjct  541  FEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYIL  600

Query  601  ADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQI  660
            ADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQI
Sbjct  601  ADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQI  660

Query  661  ELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGI  720
            ELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGI
Sbjct  661  ELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGI  720

Query  721  SDFGLSNNLGITRKQAKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDI  780
            SDFGLSNNLGITRKQ+KSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDI
Sbjct  721  SDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDI  780

Query  781  NSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEV  840
            NSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEV
Sbjct  781  NSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEV  840

Query  841  PNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880
            PNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK
Sbjct  841  PNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

11) polA.1 in NC_004070


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score = 1421 bits (5394),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 874/880 (99%), Positives = 878/880 (99%), Gaps = 0/880 (0%)

Query  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVQPTHV  60
            MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRV+PTHV
Sbjct  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60

Query  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFPYIREMLTALGIAYYELEHYEADDII  120
            LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQF+YIREMLTALGIAYYELEHYEADDII
Sbjct  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120

Query  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180
            GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT
Sbjct  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180

Query  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHKFGSLEGIYEHIDGFKASKMKENLIN  240
            PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLH FGSLEGIYEHIDGFK+SKMKENLIN
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQE  300
            DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQE
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQE  300

Query  301  PVAAISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLAT  360
            PVA ISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLAT
Sbjct  301  PVAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLAT  360

Query  361  DSFKQVFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIFT  420
            DSFKQVFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIFT
Sbjct  361  DSFKQVFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIFT  420

Query  421  DISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNIE  480
            DISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNIE
Sbjct  421  DISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNIE  480

Query  481  LPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSIL  540
            LPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSIL
Sbjct  481  LPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSIL  540

Query  541  FEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYIL  600
            FEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYIL
Sbjct  541  FEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYIL  600

Query  601  ADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQI  660
            ADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQI
Sbjct  601  ADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQI  660

Query  661  ELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGI  720
            ELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGI
Sbjct  661  ELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGI  720

Query  721  SDFGLSNNLGITRKQAKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDI  780
            SDFGLSNNLGITRKQ+KSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDI
Sbjct  721  SDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDI  780

Query  781  NSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEV  840
            NSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEV
Sbjct  781  NSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEV  840

Query  841  PNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880
            PNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK
Sbjct  841  PNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

12) SPs0149 in NC_004606


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score = 1421 bits (5394),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 874/880 (99%), Positives = 878/880 (99%), Gaps = 0/880 (0%)

Query  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVQPTHV  60
            MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRV+PTHV
Sbjct  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60

Query  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFPYIREMLTALGIAYYELEHYEADDII  120
            LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQF+YIREMLTALGIAYYELEHYEADDII
Sbjct  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120

Query  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180
            GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT
Sbjct  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180

Query  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHKFGSLEGIYEHIDGFKASKMKENLIN  240
            PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLH FGSLEGIYEHIDGFK+SKMKENLIN
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQE  300
            DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQE
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQE  300

Query  301  PVAAISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLAT  360
            PVA ISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLAT
Sbjct  301  PVAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLAT  360

Query  361  DSFKQVFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIFT  420
            DSFKQVFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIFT
Sbjct  361  DSFKQVFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIFT  420

Query  421  DISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNIE  480
            DISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNIE
Sbjct  421  DISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNIE  480

Query  481  LPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSIL  540
            LPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSIL
Sbjct  481  LPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSIL  540

Query  541  FEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYIL  600
            FEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYIL
Sbjct  541  FEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYIL  600

Query  601  ADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQI  660
            ADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQI
Sbjct  601  ADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQI  660

Query  661  ELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGI  720
            ELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGI
Sbjct  661  ELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGI  720

Query  721  SDFGLSNNLGITRKQAKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDI  780
            SDFGLSNNLGITRKQ+KSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDI
Sbjct  721  SDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDI  780

Query  781  NSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEV  840
            NSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEV
Sbjct  781  NSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEV  840

Query  841  PNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880
            PNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK
Sbjct  841  PNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

13) polA in NC_008024


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score = 1420 bits (5390),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 873/880 (99%), Positives = 879/880 (99%), Gaps = 0/880 (0%)

Query  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVQPTHV  60
            MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRV+PTHV
Sbjct  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60

Query  61   LVAFDAGKTTFRTEMYADYKAGRAKTPEEFREQFPYIREMLTALGIAYYELEHYEADDII  120
            LVAFDAGKTTFRTEMYADYKAGRAKTP+EFREQF+YIREMLTALGIAYYELEHYEADDII
Sbjct  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120

Query  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTAAYLMEKMGLT  180
            GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFT+AYLMEKMGLT
Sbjct  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180

Query  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240
            PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQE  300
            DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQE
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQE  300

Query  301  PVAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLAT  360
            PVAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLAT
Sbjct  301  PVAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLAT  360

Query  361  DSFKQVFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIFT  420
            DSFKQVFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIFT
Sbjct  361  DSFKQVFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIFT  420

Query  421  DISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNIE  480
            DISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNIE
Sbjct  421  DISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNIE  480

Query  481  LPLANVLAKMEIEGIKVNRTTLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSIL  540
            LPLANVLAKMEIEGIKVNR+TLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSIL
Sbjct  481  LPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSIL  540

Query  541  FEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYIL  600
            FEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYIL
Sbjct  541  FEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYIL  600

Query  601  ADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQI  660
            ADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQI
Sbjct  601  ADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQI  660

Query  661  ELRVLAHISGDKHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGI  720
            ELRVLAHISGD HLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGI
Sbjct  661  ELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGI  720

Query  721  SDFGLSNNLGITRKQAKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDI  780
            SDFGLSNNLGITRKQ+KSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDI
Sbjct  721  SDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDI  780

Query  781  NSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEV  840
            NSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEV
Sbjct  781  NSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEV  840

Query  841  PNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880
            PNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK
Sbjct  841  PNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

14) polA in NC_007296


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score = 1420 bits (5388),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 873/880 (99%), Positives = 878/880 (99%), Gaps = 0/880 (0%)

Query  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVQPTHV  60
            MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRV+PTHV
Sbjct  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60

Query  61   LVAFDAGKTTFRTEMYADYKAGRAKTPEEFREQFPYIREMLTALGIAYYELEHYEADDII  120
            LVAFDAGKTTFRTEMYADYKAGRAKTP+EFREQF+YIREMLTALGIAYYELEHYEADDII
Sbjct  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120

Query  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180
            GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT
Sbjct  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180

Query  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKASKMKENLIN  240
            PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFK+SKMKENLIN
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQE  300
            DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQE
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQE  300

Query  301  PVAAISYQEVTNVSADLFSAEDIFYFETLRDNYHCEAIIGFAWGHGEQIYASTDLSLLAT  360
            PVA ISYQEVTNVSADLFSAEDIFYFETLRDNYH EAIIGFAWGHGEQIYASTDLSLLAT
Sbjct  301  PVAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLAT  360

Query  361  DSFKQVFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIFT  420
            DSFKQVFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIFT
Sbjct  361  DSFKQVFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIFT  420

Query  421  DISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNIE  480
            DISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNIE
Sbjct  421  DISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNIE  480

Query  481  LPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSIL  540
            LPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSIL
Sbjct  481  LPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSIL  540

Query  541  FEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYIL  600
            FEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYIL
Sbjct  541  FEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYIL  600

Query  601  ADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQI  660
            ADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQI
Sbjct  601  ADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQI  660

Query  661  ELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGI  720
            ELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGI
Sbjct  661  ELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGI  720

Query  721  SDFGLSNNLGITRKQAKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDI  780
            SDFGLSNNLGITRKQ+KSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDI
Sbjct  721  SDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDI  780

Query  781  NSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEV  840
            NSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEV
Sbjct  781  NSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEV  840

Query  841  PNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880
            PNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK
Sbjct  841  PNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

15) SDE12394_10115 in NC_017567


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score = 1419 bits (5387),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 871/880 (99%), Positives = 877/880 (99%), Gaps = 0/880 (0%)

Query  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVQPTHV  60
            MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRV+PTHV
Sbjct  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60

Query  61   LVAFDAGKTTFRTEMYADYKAGRAKTPEEFREQFPYIREMLTALGIAYYELEHYEADDII  120
            LVAFDAGKTTFRTEMYADYKAGRAKTP+EFREQF+YIREMLTALGIAYYELEHYEADDII
Sbjct  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120

Query  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180
            GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT
Sbjct  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180

Query  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHKFGSLEGIYEHIDGFKASKMKENLIN  240
            PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLH FGSLEGIYEHIDGFK+SKMKENLIN
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQE  300
            DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQE
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQE  300

Query  301  PVAAISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLAT  360
            PVA ISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLAT
Sbjct  301  PVAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLAT  360

Query  361  DSFKQVFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIFT  420
            DSFKQVFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIFT
Sbjct  361  DSFKQVFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIFT  420

Query  421  DISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNIE  480
            DISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNIE
Sbjct  421  DISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNIE  480

Query  481  LPLANVLAKMEIEGIKVNRATLQDMAEQNKAIIEALTQEIYDMAGQEFNINSPKQLGSIL  540
            LPLANVLAKMEIEGIKVNRATLQDMAEQNK IIEALTQEIYDMAGQEFNINSPKQLGSIL
Sbjct  481  LPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSIL  540

Query  541  FEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYIL  600
            FEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYIL
Sbjct  541  FEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYIL  600

Query  601  TDGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQI  660
            +DGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQI
Sbjct  601  ADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQI  660

Query  661  ELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGI  720
            ELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGI
Sbjct  661  ELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGI  720

Query  721  SDFGLSNNLGITRKQAKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDI  780
            SDFGLSNNLGITRKQ+KSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDI
Sbjct  721  SDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDI  780

Query  781  NSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEV  840
            NSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEV
Sbjct  781  NSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEV  840

Query  841  PNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880
            PNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK
Sbjct  841  PNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

16) M6_Spy0205 in NC_006086


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score = 1419 bits (5384),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 871/880 (99%), Positives = 877/880 (99%), Gaps = 0/880 (0%)

Query  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVQPTHV  60
            MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRV+PTHV
Sbjct  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60

Query  61   LVAFDAGKTTFRTEMYADYKAGRAKTPEEFREQFPYIREMLTALGIAYYELEHYEADDII  120
            LVAFDAGKTTFRTEMYADYKAGRAKTP+EFREQF+YIREMLTALGIAYYELEHYEADDII
Sbjct  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120

Query  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180
            GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT
Sbjct  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180

Query  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKASKMKENLIN  240
            PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFK+SKMKENLIN
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQE  300
            DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQE
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQE  300

Query  301  PVAAISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLAT  360
            PVA ISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLAT
Sbjct  301  PVAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLAT  360

Query  361  DSFKQVFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIFT  420
            DSFKQVFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIFT
Sbjct  361  DSFKQVFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIFT  420

Query  421  DISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNIE  480
            DISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNIE
Sbjct  421  DISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNIE  480

Query  481  LPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSIL  540
            LPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSIL
Sbjct  481  LPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSIL  540

Query  541  FEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILAYRQITKLQSTYVIGLQDYIL  600
            FEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKIL YRQITKLQSTYVIGLQDYIL
Sbjct  541  FEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYIL  600

Query  601  ADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQI  660
            ADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQI
Sbjct  601  ADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQI  660

Query  661  ELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGI  720
            ELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGI
Sbjct  661  ELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGI  720

Query  721  SDFGLSNNLGITRKQAKTYIDTYFERYPRIKAYMENVVREAKDKGYVETLFKRRRELPDI  780
            SDFGLSNNLGITRKQ+K+YIDTYFERYP IKAYMENVVREAKDKGYVETLFKRRRELPDI
Sbjct  721  SDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDI  780

Query  781  NSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEV  840
            NSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEV
Sbjct  781  NSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEV  840

Query  841  PNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880
            PNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK
Sbjct  841  PNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

17) polA in NC_017040


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score = 1419 bits (5384),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 871/880 (99%), Positives = 877/880 (99%), Gaps = 0/880 (0%)

Query  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVQPTHV  60
            MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRV+PTHV
Sbjct  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60

Query  61   LVAFDAGKTTFRTEMYADYKAGRAKTPEEFREQFPYIREMLTALGIAYYELEHYEADDII  120
            LVAFDAGKTTFRTEMYADYKAGRAKTP+EFREQF+YIREMLTALGIAYYELEHYEADDII
Sbjct  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120

Query  121  GTLDKMAERTEAPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180
            GTLDKMAERTE PFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT
Sbjct  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180

Query  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKASKMKENLIN  240
            PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFK+SKMKENLIN
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQE  300
            DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQE
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQE  300

Query  301  PVAAISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYVSTDLSLLAT  360
            PVA ISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIY STDLSLLAT
Sbjct  301  PVAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLAT  360

Query  361  DSFKQVFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIFT  420
            DSFKQVFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIFT
Sbjct  361  DSFKQVFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIFT  420

Query  421  DISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNIE  480
            DISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNIE
Sbjct  421  DISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNIE  480

Query  481  LPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSIL  540
            LPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSIL
Sbjct  481  LPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSIL  540

Query  541  FEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYIL  600
            FEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYIL
Sbjct  541  FEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYIL  600

Query  601  ADGKIHTRYVQDFTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQI  660
            ADGKIHTRYVQD+TQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQI
Sbjct  601  ADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQI  660

Query  661  ELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGI  720
            ELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGI
Sbjct  661  ELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGI  720

Query  721  SDFGLSNNLGITRKQAKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDI  780
            SDFGLSNNLGITRKQ+KSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDI
Sbjct  721  SDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDI  780

Query  781  NSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEV  840
            NSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEV
Sbjct  781  NSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEV  840

Query  841  PNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880
            PNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK
Sbjct  841  PNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

18) polA in NC_017053


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score = 1419 bits (5384),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 871/880 (99%), Positives = 877/880 (99%), Gaps = 0/880 (0%)

Query  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVQPTHV  60
            MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRV+PTHV
Sbjct  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60

Query  61   LVAFDAGKTTFRTEMYADYKAGRAKTPEEFREQFPYIREMLTALGIAYYELEHYEADDII  120
            LVAFDAGKTTFRTEMYADYKAGRAKTP+EFREQF+YIREMLTALGIAYYELEHYEADDII
Sbjct  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120

Query  121  GTLDKMAERTEAPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180
            GTLDKMAERTE PFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT
Sbjct  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180

Query  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKASKMKENLIN  240
            PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFK+SKMKENLIN
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQE  300
            DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQE
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQE  300

Query  301  PVAAISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYVSTDLSLLAT  360
            PVA ISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIY STDLSLLAT
Sbjct  301  PVAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLAT  360

Query  361  DSFKQVFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIFT  420
            DSFKQVFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIFT
Sbjct  361  DSFKQVFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIFT  420

Query  421  DISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNIE  480
            DISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNIE
Sbjct  421  DISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNIE  480

Query  481  LPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSIL  540
            LPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSIL
Sbjct  481  LPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSIL  540

Query  541  FEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYIL  600
            FEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYIL
Sbjct  541  FEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYIL  600

Query  601  ADGKIHTRYVQDFTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQI  660
            ADGKIHTRYVQD+TQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQI
Sbjct  601  ADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQI  660

Query  661  ELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGI  720
            ELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGI
Sbjct  661  ELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGI  720

Query  721  SDFGLSNNLGITRKQAKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDI  780
            SDFGLSNNLGITRKQ+KSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDI
Sbjct  721  SDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDI  780

Query  781  NSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEV  840
            NSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEV
Sbjct  781  NSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEV  840

Query  841  PNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880
            PNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK
Sbjct  841  PNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

19) polA in NC_011375


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score = 1417 bits (5377),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 871/880 (99%), Positives = 877/880 (99%), Gaps = 0/880 (0%)

Query  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVQPTHV  60
            MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRV+PTHV
Sbjct  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60

Query  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFPYIREMLTALGIAYYELEHYEADDII  120
            LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQF+YIREMLTALGIAYYELEHYEADDII
Sbjct  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120

Query  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180
            GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT
Sbjct  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180

Query  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKASKMKENLIN  240
            PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFK+SKMKENLIN
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQE  300
            DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQE
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQE  300

Query  301  PVAAISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYVSTDLSLLAT  360
            PVA ISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIY STDLSLLAT
Sbjct  301  PVAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLAT  360

Query  361  DSFKQVFQKPIATYDFKRSKVLLSHLGIEVVAPSYDARLANYLLSTVEDNELSTIARIFT  420
            DSFKQVFQKPIATYDFKRSKVLLSHLGIE+VAPSYDARLANYLLSTVEDNELSTIARIFT
Sbjct  361  DSFKQVFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIFT  420

Query  421  DISLEEDDTVYGKGTKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNIE  480
            DISLEEDDTVYGKG+KRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNIE
Sbjct  421  DISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNIE  480

Query  481  LPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSIL  540
            LPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSIL
Sbjct  481  LPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSIL  540

Query  541  FEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYIL  600
            FEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYIL
Sbjct  541  FEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYIL  600

Query  601  ADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQI  660
            ADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQI
Sbjct  601  ADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQI  660

Query  661  ELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGI  720
            ELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGI
Sbjct  661  ELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGI  720

Query  721  SDFGLSNNLGITRKQAKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDI  780
            SDFGLSNNLGITRKQ+KSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDI
Sbjct  721  SDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDI  780

Query  781  NSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKCLLQVHDEIVLEV  840
            NSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAK LLQVHDEIVLEV
Sbjct  781  NSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEV  840

Query  841  PNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880
            PNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK
Sbjct  841  PNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

20) polA in NC_018712


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score = 1405 bits (5332),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 865/880 (99%), Positives = 876/880 (99%), Gaps = 0/880 (0%)

Query  45   MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVQPTHV  104
            MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRV+PTHV
Sbjct  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60

Query  105  LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFPYIREMLTALGIAYYELEHYEADDII  164
            LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQF+YIREMLTALGIAYYELEHYEADDII
Sbjct  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120

Query  165  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  224
            GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT
Sbjct  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180

Query  225  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHVEGFKASKMKENLIN  284
            PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEH++GFK+SKMKENLIN
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  285  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQE  344
            DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQE
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQE  300

Query  345  PVAAISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLAT  404
            PVA ISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLAT
Sbjct  301  PVAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLAT  360

Query  405  DSFKQVFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIFT  464
            DSFKQVFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIFT
Sbjct  361  DSFKQVFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIFT  420

Query  465  DISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNIE  524
            DISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNIE
Sbjct  421  DISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNIE  480

Query  525  LPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSIL  584
            LPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSIL
Sbjct  481  LPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSIL  540

Query  585  FEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYIL  644
            FEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYIL
Sbjct  541  FEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYIL  600

Query  645  ADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSQEDAVLLSSDYSQI  704
            ADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPS+EDAVLLSSDYSQI
Sbjct  601  ADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQI  660

Query  705  ELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAEDVTANDRRNAKAVNFGIVYGI  764
            ELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKA DVTANDRRNAKAVNFGIVYGI
Sbjct  661  ELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGI  720

Query  765  SDFGLSNNLGITRKQAKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDI  824
            SDFGLSNNLGITRKQ+KSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDI
Sbjct  721  SDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDI  780

Query  825  NSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDNALQAGGFKAKMLLQVHDEIVLEV  884
            NSRNFNVRSFAERTAINSPIQGSAADILKIAMINLD+ALQAGGF+AKMLLQVHDEIVLEV
Sbjct  781  NSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEV  840

Query  885  PNDELTAIKKLVKDTMEAAVDLAVPLRADENAGQSWYEAK  924
            PNDELTAIKKLVKDTMEAAVDLAVPL  DE++GQSWYEAK
Sbjct  841  PNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

21) SDEG_2002 in NC_012891


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score = 1366 bits (5183),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 828/880 (95%), Positives = 866/880 (99%), Gaps = 0/880 (0%)

Query  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLEHMMKRVQPTHV  60
            MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLML+HMMKRV+PTHV
Sbjct  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60

Query  61   LVAFDAGKTTFRTEMYADYKAGRAKTPEEFREQFPYIREMLTALGIAYYELEHYEADDII  120
            LVAFDAGKTTFRTEMYADYKAGRAKTP+EFREQF+YIREMLTALGIAYYELEHYEADDII
Sbjct  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120

Query  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVIEISKKGVAEFEEFTPAYLMEKMGLT  180
            GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTV+EISKKGVAEFEEFTPAYLMEKMGLT
Sbjct  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180

Query  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHVEGFKASKMKENLLN  240
            PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEH++GFK+SKMKENL+N
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSKFYDEMDFVQLKKGLASQMPQE  300
            DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLS+FYDEMDFVQLKKGLASQMPQE
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQE  300

Query  301  AIAAVSYQEVTSLSDDLFSDEDIFYFEVLRDNYHREDIIGFAWGHGEQIYAstdlsllst  360
            ++A +SYQEVT++S DLFS EDIFYFE LRDNYHRE IIGFAWGHGEQIYASTDLSLL+T
Sbjct  301  PVAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLAT  360

Query  361  dlFKKVFEKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSNVEDNELTTIARLFT  420
            D FK+VF+KPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLS VEDNEL+TIAR+FT
Sbjct  361  DSFKQVFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIFT  420

Query  421  DISLEADDSIYGKGVKRAVPEKEVLLGHLARKVKVLLDSRAPMVEKLADHDQIDLYHEIE  480
            DISLE DD++YGKG KRAVP+K+VLL HLARKVKVLLDS++ M++KL+ H+Q+DLY++IE
Sbjct  421  DISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNIE  480

Query  481  LPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSIL  540
            LPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSIL
Sbjct  481  LPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSIL  540

Query  541  FEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYIL  600
            FEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYIL
Sbjct  541  FEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYIL  600

Query  601  ADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQI  660
            ADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQI
Sbjct  601  ADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQI  660

Query  661  ELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGI  720
            ELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGI
Sbjct  661  ELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGI  720

Query  721  SDFGLSNNLGITRKQAKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDI  780
            SDFGLSNNLGITRKQ+KSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDI
Sbjct  721  SDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDI  780

Query  781  NSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDNALQAGGFKAKMLLQVHDEIVLEV  840
            NSRNFNVRSFAERTAINSPIQGSAADILKIAMINLD+ALQAGGF+AKMLLQVHDEIVLEV
Sbjct  781  NSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEV  840

Query  841  PNDELTAIKKLVKDTMEAAVDLAVPLRADENAGQSWYEAK  880
            PNDELTAIKKLVKDTMEAAVDLAVPL  DE++GQSWYEAK
Sbjct  841  PNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

22) SEQ_0252 in NC_012471


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score = 1303 bits (4942),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 760/880 (87%), Positives = 842/880 (96%), Gaps = 0/880 (0%)

Query  7    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVQPTHV  66
            MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRV+PTHV
Sbjct  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60

Query  67   LVAFDAGKTTFRTELFADYKAGRAKTPDEFREQFPYIRDMLGALGIAFYELEHYEADDII  126
            LVAFDAGKTTFRTE++ADYKAGRAKTPDEFREQF+YIR+ML ALGIA+YELEHYEADDII
Sbjct  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120

Query  127  GTLDKMAERTEIPFDVTIVSGDKDLIQLTDANTVVEISKKGVAEFEEFTPAYLMDKMGLT  186
            GTLDKMAERTE+PFDVTIVSGDKDLIQLTD NTVVEISKKGVAEFEEFTPAYLM+KMGLT
Sbjct  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180

Query  187  PEQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEYGSLEGIYEHIDSFKPSKMKENLLH  246
            P+QFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHE+GSLEGIYEHID+FK SKMKENL++
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  247  DKEQAFLSKTLATINTSAPITIGLEDIVYQGPDLDRLSQFYDEMDFVQLKNALASQLPQE  306
            D++QAFLSKTLATINT++PITIGL+DIVY+GPD+  LSQFYDEMDFVQLK++LASQ+PQE
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQE  300

Query  307  PVAEIAYQEVTDIRADMFSDDTVFYFEALRDNYHREELIGFAWGNQGQIYASADISLLTT  366
            PVA I+YQEVT++ AD+FS + +FYFE+LRDNYHRE +IGFAWG+  QIYAS+D+SLL+T
Sbjct  301  PVAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLAT  360

Query  367  KLFKKVLEQPIATYDFKRSKVLLSHLGLDLPAASYDARLANYLLSTVEDNEMATLARLYT  426
              FK+V+++PIATYDFKRSKVLLSHLG++L A+SYDARLANYLLSTVEDNE++T+AR++T
Sbjct  361  DSFKQVFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIFT  420

Query  427  TISLDTDEVVYGKGVKRAVPDKAVLLGHLARKVQVLLDSRPVMLDKLAEHEQADLYTDIE  486
             ISL+ D+ VYGKG KRAVPDK VLL HLARKV+VLLDS++ MLDKL+ HEQ DLY +IE
Sbjct  421  DISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNIE  480

Query  487  LPLANVLAKMEIEGIAVNQDSLQEMAEQNKVVIEELTQEIYEMAGEVFNINSPKQLGVIL  546
            LPLANVLAKMEIEGI VN+ +LQ+MAEQNKV+IE LTQEIY+MAG+ FNINSPKQLG IL
Sbjct  481  LPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSIL  540

Query  547  FEKMQLPLHLTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYIM  606
            FEKMQLPL++TKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYI+
Sbjct  541  FEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYIL  600

Query  607  ADGRIHTRYLQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHDDAVLLSSDYSQI  666
            ADG+IHTRY+QDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSH+DAVLLSSDYSQI
Sbjct  601  ADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQI  660

Query  667  ELRVLAHISGDEHLIAAFKEGADIHTSTAMRVFGIEKPEDVTANDRRNAKAVNFGIVYGI  726
            ELRVLAHISGDEHLIAAF+EGADIHTSTAMRVFGI+K+ DVTANDRRNAKAVNFGIVYGI
Sbjct  661  ELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGI  720

Query  727  SDFGLSNNLGIPRKQAKAYIDTYFERYPGIKAYMERVVREAKDKGYVETLFKRRRQLPDI  786
            SDFGLSNNLGI RKQ+K+YIDTYFERYPGIKAYME VVREAKDKGYVETLFKRRR+LPDI
Sbjct  721  SDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDI  780

Query  787  NSRQFNVRSFAERTAINSPIQGSAADILKIAMINLDQALVAGGFETKMLLQVHDEIVLEV  846
            NSR+FNVRSFAERTAINSPIQGSAADILKIAMINLD+AL AGGF +KMLLQVHDEIVLEV
Sbjct  781  NSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEV  840

Query  847  PNHELAAVKALVKETMESAVSLAVPLRVDESAGKSWYEAK  886
            PN+EL+A+K LVK+TME+AV LAVPL VDES+G+SWYEAK
Sbjct  841  PNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

23) SZO_01560 in NC_012470


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score = 1302 bits (4940),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 755/880 (86%), Positives = 843/880 (96%), Gaps = 0/880 (0%)

Query  7    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVQPTHV  66
            MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRV+PTHV
Sbjct  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60

Query  67   LVAFDAGKTTFRTELFADYKAGRAKTPDEFREQFPYIRDMLGALGIAFYELEHYEADDII  126
            LVAFDAGKTTFRTE++ADYKAGRAKTPDEFREQF+YIR+ML ALGIA+YELEHYEADDII
Sbjct  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120

Query  127  GTLDKMAERTEIPFDVTIVSGDKDLIQLTDANTVVEISKKGVAEFEEFTPAYLMDKMGLT  186
            GTLDKMAERTE+PFDVTIVSGDKDLIQLTD NTVVEISKKGVAEFEEFTPAYLM+KMGLT
Sbjct  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180

Query  187  PEQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEYGSLEGIYQHVDSFKPSKMKENLLH  246
            P+QFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHE+GSLEGIY+H+D+FK SKMKENL++
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  247  DKEQAFLSKTLATINTSAPIAIGLEDIVYQGPDLDRLSQFYDEMDFVQLKNALASQLPQE  306
            D++QAFLSKTLATINT++PI+IGL+DIVY+GPD+  LSQFYDEMDFVQLK++LASQ+PQE
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQE  300

Query  307  PVAEIAYQEVTDIRADMFSDDTVFYFEALRDNYHREELIGFAWGNQGQIYASADISLLTT  366
            PVA I+YQEVT++ AD+FS + +FYFE+LRDNYHRE +IGFAWG+  QIYAS+D+SLL+T
Sbjct  301  PVAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLAT  360

Query  367  ELFKKVLEQPIATYDFKRSKVLLSHLGLDLPAASYDARLANYLLSTVEDNEMATLARLYT  426
            + FK+V+++PIATYDFKRSKVLLSHLG++L A+SYDARLANYLLSTVEDNE++T+AR++T
Sbjct  361  DSFKQVFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIFT  420

Query  427  TIPLDTDEVVYGKGVKRAVPDKAVLLGHLARKVQVLLDSRPVMLDKLAEHEQADLYTDIE  486
             I+L+ D+ VYGKG KRAVPDK VLL HLARKV+VLLDS++ MLDKL+ HEQ DLY +IE
Sbjct  421  DISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNIE  480

Query  487  LPLANVLAKMEIEGIAVNQDSLQEMAEQNKVVIEELTQEIYEMAGEVFNINSPKQLGVIL  546
            LPLANVLAKMEIEGI VN+ +LQ+MAEQNKV+IE LTQEIY+MAG+ FNINSPKQLG IL
Sbjct  481  LPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSIL  540

Query  547  FEKMQLPLHLTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYIM  606
            FEKMQLPL++TKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYI+
Sbjct  541  FEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYIL  600

Query  607  ADGRIHTRYLQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHDDAVLLSSDYSQI  666
            ADG+IHTRY+QDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSH+DAVLLSSDYSQI
Sbjct  601  ADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQI  660

Query  667  ELRVLAHISGDEHLIAAFKEGADIHTSTAMRVFGIEKPEDVTANDRRNAKAVNFGIVYGI  726
            ELRVLAHISGDEHLIAAF+EGADIHTSTAMRVFGI+K+ DVTANDRRNAKAVNFGIVYGI
Sbjct  661  ELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGI  720

Query  727  SDFGLSNNLGIPRKQAKAYIDTYFERYPGIKDYMERVVREAKDKGYVETLFKRRRQLPDI  786
            SDFGLSNNLGI RKQ+K+YIDTYFERYPGIK YME VVREAKDKGYVETLFKRRR+LPDI
Sbjct  721  SDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDI  780

Query  787  NSRQFNVRSFAERTAINSPIQGSAADILKIAMINLDQALVAGGFETKMLLQVHDEIVLEV  846
            NSR+FNVRSFAERTAINSPIQGSAADILKIAMINLD+AL AGGF +KMLLQVHDEIVLEV
Sbjct  781  NSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEV  840

Query  847  PNHELAAVKELVKETMESAVNLAVPLRVDESAGKSWYEAK  886
            PN+EL+A+K LVK+TME+AV+LAVPL VDES+G+SWYEAK
Sbjct  841  PNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

24) polA in NC_008023


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score = 1300 bits (4934),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 806/806 (100%), Positives = 806/806 (100%), Gaps = 0/806 (0%)

Query  1    MYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLDKMAERTEVPF  60
            MYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLDKMAERTEVPF
Sbjct  75   MYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLDKMAERTEVPF  134

Query  61   DVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQFIDLKALMGDK  120
            DVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQFIDLKALMGDK
Sbjct  135  DVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQFIDLKALMGDK  194

Query  121  SDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRDQAFLSKTLATI  180
            SDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRDQAFLSKTLATI
Sbjct  195  SDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRDQAFLSKTLATI  254

Query  181  NTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEPVAVISYQEVTNVS  240
            NTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEPVAVISYQEVTNVS
Sbjct  255  NTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEPVAVISYQEVTNVS  314

Query  241  ADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLATDSFKQVFQKPIATY  300
            ADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLATDSFKQVFQKPIATY
Sbjct  315  ADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLATDSFKQVFQKPIATY  374

Query  301  DFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIFTDISLEEDDTVYGKG  360
            DFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIFTDISLEEDDTVYGKG
Sbjct  375  DFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIFTDISLEEDDTVYGKG  434

Query  361  AKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNIELPLANVLAKMEIEG  420
            AKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNIELPLANVLAKMEIEG
Sbjct  435  AKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNIELPLANVLAKMEIEG  494

Query  421  IKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSILFEKMQLPLEMTKKT  480
            IKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSILFEKMQLPLEMTKKT
Sbjct  495  IKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSILFEKMQLPLEMTKKT  554

Query  481  KTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYILADGKIHTRYVQDLT  540
            KTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYILADGKIHTRYVQDLT
Sbjct  555  KTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYILADGKIHTRYVQDLT  614

Query  541  QTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQIELRVLAHISGDEHL  600
            QTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQIELRVLAHISGDEHL
Sbjct  615  QTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQIELRVLAHISGDEHL  674

Query  601  IAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGISDFGLSNNLGITRK  660
            IAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGISDFGLSNNLGITRK
Sbjct  675  IAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGISDFGLSNNLGITRK  734

Query  661  QSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDINSRNFNVRSFAERT  720
            QSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDINSRNFNVRSFAERT
Sbjct  735  QSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDINSRNFNVRSFAERT  794

Query  721  AINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEVPNDELTAIKKLVKD  780
            AINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEVPNDELTAIKKLVKD
Sbjct  795  AINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEVPNDELTAIKKLVKD  854

Query  781  TMEAAVDLAVPLCVDESTGQSWYEAK  806
            TMEAAVDLAVPLCVDESTGQSWYEAK
Sbjct  855  TMEAAVDLAVPLCVDESTGQSWYEAK  880

25) polA in NC_011134


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score = 1300 bits (4934),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 755/880 (86%), Positives = 844/880 (96%), Gaps = 0/880 (0%)

Query  20   MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVQPTHV  79
            MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRV+PTHV
Sbjct  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60

Query  80   LVAFDAGKTTFRTELFADYKAGRAKTPDEFREQFPYIRDMLGALGIAFYELEHYEADDII  139
            LVAFDAGKTTFRTE++ADYKAGRAKTPDEFREQF+YIR+ML ALGIA+YELEHYEADDII
Sbjct  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120

Query  140  GTLDKMAERTELPFDVTIVSGDKDLIQLTDANTVVEISKKGVAEFEEFTPAYLMDKMGLT  199
            GTLDKMAERTE+PFDVTIVSGDKDLIQLTD NTVVEISKKGVAEFEEFTPAYLM+KMGLT
Sbjct  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180

Query  200  PEQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEYGSLEGIYQHVDSFKPSKMKENLLH  259
            P+QFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHE+GSLEGIY+H+D+FK SKMKENL++
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  260  DKEQAFLSKTLATINTSAPITIGLEDIVYQGPDLDRLSQFYDEMDFVQLKNALASQLPQE  319
            D++QAFLSKTLATINT++PITIGL+DIVY+GPD+  LSQFYDEMDFVQLK++LASQ+PQE
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQE  300

Query  320  PVAEIAYQEVTDIRADMFSDDTVFYFEALRDNYHREELIGFAWGNQGQIYASADISLLTT  379
            PVA I+YQEVT++ AD+FS + +FYFE+LRDNYHRE +IGFAWG+  QIYAS+D+SLL+T
Sbjct  301  PVAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLAT  360

Query  380  ELFKKVLEQPIATYDFKRSKVLLSHLGLDLPAASYDARLANYLLSTVEDNEMATLARLYT  439
            + FK+V+++PIATYDFKRSKVLLSHLG++L A+SYDARLANYLLSTVEDNE++T+AR++T
Sbjct  361  DSFKQVFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIFT  420

Query  440  TIPLDTDEVVYGKGVKRAVPDKAVLLGHLARKVQVLLDSRPVMLDKLAEHEQADLYTDIE  499
             I+L+ D+ VYGKG KRAVPDK VLL HLARKV+VLLDS++ MLDKL+ HEQ DLY +IE
Sbjct  421  DISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNIE  480

Query  500  LPLANVLAKMEIEGIAVNQDSLQEMAEQNKVVIEELTQEIYEMAGEVFNINSPKQLGVIL  559
            LPLANVLAKMEIEGI VN+ +LQ+MAEQNKV+IE LTQEIY+MAG+ FNINSPKQLG IL
Sbjct  481  LPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSIL  540

Query  560  FEKMQLPLHLTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYIM  619
            FEKMQLPL++TKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYI+
Sbjct  541  FEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYIL  600

Query  620  ADGRIHTRYLQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHDDAVLLSSDYSQI  679
            ADG+IHTRY+QDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSH+DAVLLSSDYSQI
Sbjct  601  ADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQI  660

Query  680  ELRVLAHISGDEHLIAAFKEGADIHTSTAMRVFGIEKPEDVTANDRRNAKAVNFGIVYGI  739
            ELRVLAHISGDEHLIAAF+EGADIHTSTAMRVFGI+K+ DVTANDRRNAKAVNFGIVYGI
Sbjct  661  ELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGI  720

Query  740  SDFGLSNNLGIPRKQAKAYIDTYFERYPGIKAYMERVVREAKDKGYVETLFKRRRQLPDI  799
            SDFGLSNNLGI RKQ+K+YIDTYFERYPGIKAYME VVREAKDKGYVETLFKRRR+LPDI
Sbjct  721  SDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDI  780

Query  800  NSRQFNLRSFAERTAINSPIQGSAADILKIAMINLDQALVAGGFETKMLLQVHDEIVLEV  859
            NSR+FN+RSFAERTAINSPIQGSAADILKIAMINLD+AL AGGF +KMLLQVHDEIVLEV
Sbjct  781  NSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEV  840

Query  860  PSHELAAVKELVKETMESAVNLAVPLRVDESAGKSWYEAK  899
            P++EL+A+K LVK+TME+AV+LAVPL VDES+G+SWYEAK
Sbjct  841  PNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

26) polA in NC_019042


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score = 1287 bits (4883),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 779/834 (94%), Positives = 819/834 (99%), Gaps = 0/834 (0%)

Query  1    MLDHMMKRVQPTHVLVAFDAGKTTFRTEMYADYKAGRAKTPEEFREQFPYIREMLTALGI  60
            MLDHMMKRV+PTHVLVAFDAGKTTFRTEMYADYKAGRAKTP+EFREQF+YIREMLTALGI
Sbjct  47   MLDHMMKRVRPTHVLVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGI  106

Query  61   AYYELEHYEADDIIGTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFE  120
            AYYELEHYEADDIIGTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFE
Sbjct  107  AYYELEHYEADDIIGTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFE  166

Query  121  EFTPAYLMEKMGLTPNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHV  180
            EFTPAYLMEKMGLTPNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEH+
Sbjct  167  EFTPAYLMEKMGLTPNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHI  226

Query  181  EGFKASKMKENLLNDRDQAFLSKTLATINTTSPITIGLDDIVYNGPDVASLSKFYDEMDF  240
            +GFK+SKMKENL+NDRDQAFLSKTLATINT+SPITIGLDDIVYNGPDVASLS+FYDEMDF
Sbjct  227  DGFKTSKMKENLINDRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDF  286

Query  241  VQLKKGLASQMPQEAIAAVSYQEVTSLSDDLFSDEDIFYFEVLRDNYHREDIIGFAWGHG  300
            VQLKKGLASQMPQE++A +SYQEVT++S DLFS EDIFYFE LRDNYHRE IIGFAWGHG
Sbjct  287  VQLKKGLASQMPQEPVAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHG  346

Query  301  EQIYAstdlsllstdlFKKVFEKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSN  360
            EQIYASTDLSLL+TD FK+VF+KPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLS 
Sbjct  347  EQIYASTDLSLLATDSFKQVFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLST  406

Query  361  VEDNELTTIARLFTDISLEADDSIYGKGVKRAVPEKEVLLGHLARKVKVLLDSRAPMVEK  420
            VEDNEL+TIAR+FTDISLE DD++YGKG KRAVP+K+VLL HLARKVKVLLDS++ M++K
Sbjct  407  VEDNELSTIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDK  466

Query  421  LADHDQIDLYHEIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQ  480
            L+ H+Q+DLY++IELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQ
Sbjct  467  LTAHEQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQ  526

Query  481  EFNINSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITK  540
            EFNINSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITK
Sbjct  527  EFNINSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITK  586

Query  541  LQSTYVIGLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPS  600
            LQSTYVIGLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPS
Sbjct  587  LQSTYVIGLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPS  646

Query  601  HEDAVLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDR  660
            HEDAVLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDR
Sbjct  647  HEDAVLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDR  706

Query  661  RNAKAVNFGIVYGISDFGLSNNLGITRKQAKSYIDTYFERYPGIKAYMENVVREAKDKGY  720
            RNAKAVNFGIVYGISDFGLSNNLGITRKQ+KSYIDTYFERYPGIKAYMENVVREAKDKGY
Sbjct  707  RNAKAVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGY  766

Query  721  VETLFKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDNALQAGGFKA  780
            VETLFKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLD+ALQAGGF+A
Sbjct  767  VETLFKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRA  826

Query  781  KMLLQVHDEIVLEVPNTELAAVKKLVKETMEAAVDLAVPLRADENAGQSWYEAK  834
            KMLLQVHDEIVLEVPN EL+A+KKLVK+TMEAAVDLAVPL  DE++GQSWYEAK
Sbjct  827  KMLLQVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

27) polA in NC_017582


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score = 1285 bits (4874),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 759/880 (87%), Positives = 845/880 (97%), Gaps = 0/880 (0%)

Query  7    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVQPTHV  66
            MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRV+PTHV
Sbjct  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60

Query  67   LVAFDAGKTTFRTELFADYKAGRAKTPDEFREQFPYIRDMLGALGIAFYELEHYEADDII  126
            LVAFDAGKTTFRTE++ADYKAGRAKTPDEFREQF+YIR+ML ALGIA+YELEHYEADDII
Sbjct  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120

Query  127  GTLDKMAERTELPFDVTIVSGDKDLIQLTDANTVVEISKKGVAEFEEFTPAYLMDKMGLT  186
            GTLDKMAERTE+PFDVTIVSGDKDLIQLTD NTVVEISKKGVAEFEEFTPAYLM+KMGLT
Sbjct  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180

Query  187  PEQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEYGSLEGIYQHVDSFKPSKMKENLLH  246
            P+QFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHE+GSLEGIY+H+D+FK SKMKENL++
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  247  DKEQAFLSKTLATINTSAPITIGLEDIVYQGPDLDRLSQFYDEMDFVQLKNALASQLPQE  306
            D++QAFLSKTLATINT++PITIGL+DIVY+GPD+  LSQFYDEMDFVQLK++LASQ+PQE
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQE  300

Query  307  PVAEIAYQEVTDIRADMFSDDTVFYFEALRDNYHREELIGFAWGNQEQIYASADISLLTT  366
            PVA I+YQEVT++ AD+FS + +FYFE+LRDNYHRE +IGFAWG+ EQIYAS+D+SLL+T
Sbjct  301  PVAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLAT  360

Query  367  ELFKKVLEQPIATYDFKRSKVllshlgldllAASYDARLANYLLSTVEDNEMATLARLYT  426
            + FK+V+++PIATYDFKRSKVLLSHLG++L+A+SYDARLANYLLSTVEDNE++T+AR++T
Sbjct  361  DSFKQVFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIFT  420

Query  427  TIPLDTDEVVYGKGVKRAVPDKAVLLGHLARKVQVLLDSRPVMLDKLAEHEQADLYTDIE  486
             I+L+ D+ VYGKG KRAVPDK VLL HLARKV+VLLDS++ MLDKL+ HEQ DLY +IE
Sbjct  421  DISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNIE  480

Query  487  LPLANVLAKMEIEGIAVNQDSLQEMAEQNKVVIEELTQEIYEMAGEVFNINSPKQLGVIL  546
            LPLANVLAKMEIEGI VN+ +LQ+MAEQNKV+IE LTQEIY+MAG+ FNINSPKQLG IL
Sbjct  481  LPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSIL  540

Query  547  FEKMQLPLHLTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYIM  606
            FEKMQLPL++TKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYI+
Sbjct  541  FEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYIL  600

Query  607  ADGRIHTRYLQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHDDAVLLSSDYSQI  666
            ADG+IHTRY+QDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSH+DAVLLSSDYSQI
Sbjct  601  ADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQI  660

Query  667  ELRVLAHISGDEHLIAAFKEGADIHTSTAMRVFGIEKPEDVTANDRRNAKAVNFGIVYGI  726
            ELRVLAHISGDEHLIAAF+EGADIHTSTAMRVFGI+K+ DVTANDRRNAKAVNFGIVYGI
Sbjct  661  ELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGI  720

Query  727  SDFGLSNNLGIPRKQAKAYIDTYFERYPGIKAYMERVVREAKDKGYVETLFKRRRELPDI  786
            SDFGLSNNLGI RKQ+K+YIDTYFERYPGIKAYME VVREAKDKGYVETLFKRRRELPDI
Sbjct  721  SDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDI  780

Query  787  NSRQFNVRSFAERTAINSPIQGSAADILKIAMINLDQALVAGGFETKMLLQVHDEIVLEV  846
            NSR+FNVRSFAERTAINSPIQGSAADILKIAMINLD+AL AGGF +KMLLQVHDEIVLEV
Sbjct  781  NSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEV  840

Query  847  PNHELAAVKALVKETMESAVSLAVPLRVDESAGKSWYEAK  886
            PN+EL+A+K LVK+TME+AV LAVPL VDES+G+SWYEAK
Sbjct  841  PNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

28) K710_2019 in NC_021314


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score = 1240 bits (4705),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 706/880 (81%), Positives = 810/880 (93%), Gaps = 0/880 (0%)

Query  1    MDKKNRLLLIDGSSVAFRAFFALYNQIDRFKNQAGLHTNAIYGFHLMLDHMMKRVDPTHI  60
            M++KN+LLLIDGSSVAFRAFFALYNQIDRFKN++GLHTNAIYGFHLMLDHMMKRV PTH+
Sbjct  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60

Query  61   LVAFDAGKTTFRTEMFADYKAGRAKTPEEFREQFPYIREMLTALGVPFYDLDNYEADDII  120
            LVAFDAGKTTFRTEM+ADYKAGRAKTP+EFREQF+YIREMLTALG+++Y+L++YEADDII
Sbjct  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120

Query  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180
            GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT
Sbjct  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180

Query  181  PAQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYENVDGFKASKMKENLIN  240
            P QFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYE++DGFK+SKMKENLIN
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  241  DKEQAFLSKTLATINTTSPITIGLDDLAYKGPNLDTLAAFYEDMGFHQLRAGLAQTMPEA  300
            D++QAFLSKTLATINT+SPITIGLDD+ Y+GP++ +L+ FY++M+F QL+ GLA  MP+ 
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQE  300

Query  301  EKEEINFQEVEQLTKEHFADDDVIYFEVLNENYHRESIAAFAWGNSQRIFVSENQELLKD  360
                I++QEV +++ + F+ +D++YFE L +NYHRE+I +FAWG++++I+ S +  LL  
Sbjct  301  PVAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLAT  360

Query  361  PLFKTFLAKPMATYDFKRAKVLLSHLEIAVPAAAYDARLANYLLSNVEDNELETIARLHT  420
              FK  + KP+ATYDFKR+KVLLSHL I + A++YDARLANYLLS VEDNEL TIAR+ T
Sbjct  361  DSFKQVFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIFT  420

Query  421  TMTLASDEAVYGKGVKRAFPEKAIFLDHLARKVKVLVDSRATMLAKLEEHQQSELFTDIE  480
             ++L  D++VYGKG KRA P+K ++L+HLARKVKVL+DS++ ML KL  H+Q +L+ +IE
Sbjct  421  DISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNIE  480

Query  481  LPLANVLAKMEIAGIKVNKESLVDMAEQNKIIIESLTQEIYEMAGEEFNINSPKQLGVIL  540
            LPLANVLAKMEI GIKVN+ +L DMAEQNK+IIE+LTQEIY+MAG+EFNINSPKQLG IL
Sbjct  481  LPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSIL  540

Query  541  FEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYIM  600
            FEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYI+
Sbjct  541  FEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYIL  600

Query  601  SDGKIHTRYVQDLTQTGRLSSSDPNLQNIPVRLEQGRLIRKAFTASKEGSLLLSSDYSQI  660
            +DGKIHTRYVQDLTQTGRLSS DPNLQNIP+RLEQGRLIRKAFT+S E+++LLSSDYSQI
Sbjct  601  ADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQI  660

Query  661  ELRVLAHISGDQHLIAAFNEDADIHTSTAMRVFGIAKPEDVTANDRRNAKAVNFGIVYGI  720
            ELRVLAHISGD+HLIAAFNE+ADIHTSTAMRVFGI K+ DVTANDRRNAKAVNFGIVYGI
Sbjct  661  ELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGI  720

Query  721  SDFGLSNNLGISRKQAKDYIDTYFQQYPGIKSYMDTVVREAKDKGYVETLFKRRRELPEI  780
            SDFGLSNNLGI+RKQ+K YIDTYF++YPGIK+YM+ VVREAKDKGYVETLFKRRRELP+I
Sbjct  721  SDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDI  780

Query  781  NSRNFNIRSFAERTAINSPIQGSAADILKIAMINLDKALADGQFESRMLLQVHDEIVLEV  840
            NSRNFN+RSFAERTAINSPIQGSAADILKIAMINLDKAL  G F ++MLLQVHDEIVLEV
Sbjct  781  NSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEV  840

Query  841  PEAELPAIKALVKETMEAAVALSVPLRADENAGQSWYEAK  880
            P+ EL AIK LVK+TMEAAV L+VPL  DE++GQSWYEAK
Sbjct  841  PNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

29) polA in NC_015558


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score = 1231 bits (4671),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 712/880 (81%), Positives = 813/880 (93%), Gaps = 1/880 (0%)

Query  1    MEKKNKLLLIDGSSVAFRAFFALYSQIDRFKNQSGLHTNAIYGFHLMLDHMMKRIQPTHI  60
            ME+KNKLLLIDGSSVAFRAFFALY+QIDRFKN+SGLHTNAIYGFHLMLDHMMKR++PTH+
Sbjct  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60

Query  61   LVAFDAGKTTFRTEMFADYKAGRAKTPDEFREQFPYIREMLTALGVPFYDLANYEADDII  120
            LVAFDAGKTTFRTEM+ADYKAGRAKTPDEFREQF+YIREMLTALG+++Y+L +YEADDII
Sbjct  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120

Query  121  GTLDKMAEKTEVPFDVTIVSGDKDLIQLTDANTVVEISRKGVTDFEEFTPAYLMEKMGLT  180
            GTLDKMAE+TEVPFDVTIVSGDKDLIQLTD NTVVEIS+KGV++FEEFTPAYLMEKMGLT
Sbjct  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180

Query  181  PEQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYENIDSFKASKMKENLIN  240
            P+QFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYE+ID+FK+SKMKENLIN
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  241  DKEQAFLSKTLATINTESPITIGLEDLVYHGPNVQVLMEFYDEMDFKQLKAGLETEVPQE  300
            D++QAFLSKTLATINT SPITIGL+D+VY+GP+V  L +FYDEMDF QLK GL +++PQE
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQE  300

Query  301  KAE-ISFEVVTSEDQIVFADQDLFYFEILKDNYHREDIHAFAWGNSDYIYVSKDSALLTG  359
                IS++ VT+    +F+ +D+FYFE L+DNYHRE I +FAWG+++ IY S D +LL+ 
Sbjct  301  PVAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLAT  360

Query  360  PSFTKRLAEPIATYDFKRSKVLLSHLGIDLPQANYDARLANYLLSNIEDNELATIARLHT  419
             SF + +  PIATYDFKRSKVLLSHLGI+L  ++YDARLANYLLS +EDNEL+TIAR+ T
Sbjct  361  DSFKQVFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIFT  420

Query  420  NLNMEADEVVYGKGVKRAFPEDEALFDHLARKIQVLVDSKAVILDKLAVNKEEDLYFDIE  479
            ++++E D+ VYGKG KRA P+ + L++HLARK++VL+DSK+ +LDKL+ + + DLY +IE
Sbjct  421  DISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNIE  480

Query  480  LPLANVLAKMEIAGITVNKTALQEMAEQNKAVIESLTEEIYEMAGEEFNINSPKQLGSIL  539
            LPLANVLAKMEI GI VN+++LQ+MAEQNK +IE+LT+EIY+MAG+EFNINSPKQLGSIL
Sbjct  481  LPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSIL  540

Query  540  FEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQISKLQSTYVIGLQDYIM  599
            FEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQI+KLQSTYVIGLQDYI+
Sbjct  541  FEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYIL  600

Query  600  SDGKIHTRYIQDLTQTGRLSSSDPNLQNIPVRLEQGRLIRKAFLPSSEDAVLLSSDYSQI  659
            +DGKIHTRY+QDLTQTGRLSS DPNLQNIP+RLEQGRLIRKAF PS EDAVLLSSDYSQI
Sbjct  601  ADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQI  660

Query  660  ELRVLAHISGDEHLIAAFKENADIHTSTAMRVFGIEKEEDVTPNDRRNAKAVNFGIVYGI  719
            ELRVLAHISGDEHLIAAF+E ADIHTSTAMRVFGI+K  DVT+NDRRNAKAVNFGIVYGI
Sbjct  661  ELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGI  720

Query  720  SDFGLSNNLGITRKKAKDYIETYFERYPGIKEYMETVVRDARDTGYVETLFNRRRELPDI  779
            SDFGLSNNLGITRK++K YI+TYFERYPGIK YME VVR+A+D GYVETLF+RRRELPDI
Sbjct  721  SDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDI  780

Query  780  NSRNFNIRSFAERTAINSPIQGSAADILKIAMINLDKALNEGQFKAKMLLQVHDEIVLEV  839
            NSRNFN+RSFAERTAINSPIQGSAADILKIAMINLDKAL+ G F+AKMLLQVHDEIVLEV
Sbjct  781  NSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEV  840

Query  840  PNDELEAIKALVKKTMEGAVDLAVPLLADENTGKTWYEAK  879
            PNDEL AIK LVK TME+AVDLAVPL  DE+TG++WYEAK
Sbjct  841  PNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

30) polA in NC_012004


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score = 1205 bits (4571),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 700/881 (80%), Positives = 815/881 (93%), Gaps = 1/881 (0%)

Query  1    MENKNRLLLIDGSSVAFRAFFALYQQIDRFRNQAGLHTNAIYGFHLMLDHMMKRVQPTHI  60
            MENKN+LLLIDGSSVAFRAFFALY+QIDRF+N++GLHTNAIYGFHLMLDHMMKRV+PTH+
Sbjct  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60

Query  61   LVAFDAGKTTFRTEMYADYKGGRAKTPDEFREQFPYIREMLKALGVPYYDLVNYEADDII  120
            LVAFDAGKTTFRTEMYADYK+GRAKTPDEFREQF+YIREML ALG++YY+L +YEADDII
Sbjct  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120

Query  121  GTLDKIAERTEVPFDVTIVSGDKDLIQLTDANTVVEISKKGVAEFEEFTPDYLMEKMGIT  180
            GTLDK+AERTEVPFDVTIVSGDKDLIQLTD NTVVEISKKGVAEFEEFTP YLMEKMG+T
Sbjct  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180

Query  181  PEQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLQEYGSLEGIYANVDSFKPSKMKENLIN  240
            P+QFIDLKALMGDKSDNIPGVTKIGEKTGLKLL+E+GSLEGIY ++D+FK SKMKENLIN
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  241  DKAQAFLSKTLATIDTNAPITIGLEDLVYHGPNHEALASFYDEMGFVQLRAALSNQLPKE  300
            D+ QAFLSKTLATI+T +PITIGL+D+VY+GP+  +L+ FYDEM+FVQL+ +L++Q+P+E
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQE  300

Query  301  PEEEIVYHEVVDDISPDMFTDDTFIYFELLNDNYHREDITTFAWGNTENIYVSQNPEVLK  360
            P   I Y+EV + +S+D+F+ + ++YFE L DNYHRE I  FAWG+ E+IY S +  +L 
Sbjct  301  PVAVISYQEVTN-VSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLA  359

Query  361  TDVFQAFLRKPMATYDFKRAKILLSHLNIDVPRGAFDARLANYLLSNVDDNQLSTIARVH  420
            TD F+  ++KP+ATYDFKR+K+LLSHL I++   ++DARLANYLLS V+DN+LSTIAR+ 
Sbjct  360  TDSFKQVFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIF  419

Query  421  TNIHLESDDVVYGKGVKRAFPDKGLLFAHLAKKIKVLVESKATMLDKLSDHDQLALFEDI  480
            T+I LE DD VYGKG KRA PDK++L+ HLA+K+KVL++SK+ MLDKL+ H+QL L+++I
Sbjct  420  TDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNI  479

Query  481  EMPLANVLAKMEITGIKVNKETLVEMAEQNKVIIDRLTQEIYDLAGEEFNINSPKQLGSI  540
            E+PLANVLAKMEI GIKVN+ TL +MAEQNKVII+ LTQEIYD+AG+EFNINSPKQLGSI
Sbjct  480  ELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSI  539

Query  541  LFEKMQLPIEMTKKTKTGYSTAVDVLERLAPIAPVVAKILDYRQITKLQSTYLIGLQDYI  600
            LFEKMQLP+EMTKKTKTGYSTAVDVLERLAPIAP+VAKILDYRQITKLQSTY+IGLQDYI
Sbjct  540  LFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYI  599

Query  601  MEDGKIHTRYVQDLTQTGRLSSIDPNLQNIPIRMEQGRLIRKAFTassedalllssdysQ  660
            + DGKIHTRYVQDLTQTGRLSS+DPNLQNIPIR+EQGRLIRKAFT+S EDA+LLSSDYSQ
Sbjct  600  LADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQ  659

Query  661  IELRVLAHISGDQHLITAFNEDADIHTSTAMRVFAIDKEEDVTANDRRNAKAVNFGIVYG  720
            IELRVLAHISGD+HLI+AFNE+ADIHTSTAMRVF+IDK  DVTANDRRNAKAVNFGIVYG
Sbjct  660  IELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYG  719

Query  721  ISDFGLSNNLGISRQKAKEYINTYFDRYPGIKDYMDSIVREAKDKGYVETLFKRRRELPD  780
            ISDFGLSNNLGI+R+++K YI+TYF+RYPGIK YM+++VREAKDKGYVETLFKRRRELPD
Sbjct  720  ISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPD  779

Query  781  INSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALEEGRFKTKMLLQVHDEIVLE  840
            INSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKAL+ G F++KMLLQVHDEIVLE
Sbjct  780  INSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLE  839

Query  841  VPKDELEKVKQLVKETMEHAVDLSVPLRADENSGKSWYEAK  881
            VP+DEL  +K+LVK+TME AVDL+VPL  DE++G+SWYEAK
Sbjct  840  VPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

31) polA in NC_015760


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score = 1193 bits (4525),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 694/880 (79%), Positives = 799/880 (91%), Gaps = 1/880 (0%)

Query  1    MTNQKKLLLIDGSSVAFRAFFALYNQIDRFRNNNGLHTNAIYGFHLMLDNLLERIQPTHV  60
            M N++KLLLIDGSSVAFRAFFALYNQIDRF+N++GLHTNAIYGFHLMLD+++ R++PTHV
Sbjct  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60

Query  61   LVAFDAGKTTFRTEMFADYKAGRAKTPEEFREQFPYIREMLAARGIAYYDLAQYEADDII  120
            LVAFDAGKTTFRTEM+ADYKAGRAKTP+EFREQF+YIREML+A GIAYY+L +YEADDII
Sbjct  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120

Query  121  GTLAKMAENTSEDYQITVVSGDKDLIQLTDDNTVVEISKKGVAEFEAFTPDYLMEKMGIT  180
            GTL KMAE T   +++T+VSGDKDLIQLTD+NTVVEISKKGVAEFE FTP YLMEKMG+T
Sbjct  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180

Query  181  PAQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLLEHGSLEGIYDHIDEMKKSKMKENLIN  240
            P QFIDLKALMGDKSDNIPGVTKIGEKTGLKLL E GSLEGIY+HID  K SKMKENLIN
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  241  DKEQAFLSKTLATIDTQSPIEIGLDDTAFTGPDLEKLAAFYDEMGFVQFKNALGGEAVPK  300
            D++QAFLSKTLATI+T SPI IGLDD  + GPD+  L+ FYDEM+FVQ+K++L+++    
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQE  300

Query  301  DFDV-AYTEPSQVTEDHFSPDDFFYFEILDDNYHTEPIIGFAWGNDKQIYASTDTNLLKS  359
               V +Y E ++V+ D FS++D+FYFE L DNYH E+IIGFAWG++ QIYASTD +LL +
Sbjct  301  PVAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLAT  360

Query  360  DAFQTALSKAVNIYDFKRSKVLLSHLGIDLPTANFDARLAKYLLSTVEDNELSTIARLYT  419
            D+F+  + K++  YDFKRSKVLLSHLGI+L ++++DARLA+YLLSTVEDNELSTIAR++T
Sbjct  361  DSFKQVFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIFT  420

Query  420  DLPLETDEVVYGKGAKRAVPEKEVLLSHLAKKVKVLQVARPVMLEKLAEHGQSELLFDME  479
            D++LE D+ VYGKGAKRAVP+K+VLL HLA+KVKVL  +++ ML+KL+ H Q +L  ++E
Sbjct  421  DISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNIE  480

Query  480  LPLANVLAKMEIAGIKVKGQTLNEMAVENQVVIDKLTQEIYEMAGEEFNINSPKQLGVIL  539
            LPLANVLAKMEI GIKV+  TL++MA +N+V+I+ LTQEIY+MAG+EFNINSPKQLG IL
Sbjct  481  LPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSIL  540

Query  540  FEKMGLPLEYTKKTKTGYSTAVDVLERLAPIAPIVAKILEYRQITKLQSTYVLGLQDYIL  599
            FEKM LPLE TKKTKTGYSTAVDVLERLAPIAPIVAKIL+YRQITKLQSTYV+GLQDYIL
Sbjct  541  FEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYIL  600

Query  600  EDGKIHTRYVQDLTQTGRLSSVDPNLQNIPVRLEQGRLIRKAFVPSTEDAVLLSSDYSQI  659
             DGKIHTRYVQDLTQTGRLSSVDPNLQNIP+RLEQGRLIRKAF PS EDAVLLSSDYSQI
Sbjct  601  ADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQI  660

Query  660  ELRVLAHISGDEHLIAAFKEGADIHTSTAMRVFGIEKPEDVTPNDRRNAKAVNFGIVYGI  719
            ELRVLAHISGDEHLIAAF+EGADIHTSTAMRVFGI+K+ DVT+NDRRNAKAVNFGIVYGI
Sbjct  661  ELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGI  720

Query  720  SDFGLSNNLGISRKKAKEYIDTYFERYPGIKAYMDNVVREAKDKGYVETLFHRRRELPDI  779
            SDFGLSNNLGI+RK++K YIDTYFERYPGIKAYM+NVVREAKDKGYVETLF RRRELPDI
Sbjct  721  SDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDI  780

Query  780  NSRNFNVRNFAERTAINSPIQGSAADILKIAMINLDKALVEGGYKTKMLLQVHDEIVLEV  839
            NSRNFNVR+FAERTAINSPIQGSAADILKIAMINLDKAL  GG+++KMLLQVHDEIVLEV
Sbjct  781  NSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEV  840

Query  840  PNDELVAMKTLVKETMEAAVELAVPLIADENDGRTWYEAK  879
            PNDEL A+K LVK+TMEAAV+LAVPL  DE+ G++WYEAK
Sbjct  841  PNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

32) polA in NC_017595


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score = 1175 bits (4458),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 697/881 (80%), Positives = 801/881 (91%), Gaps = 3/881 (0%)

Query  1    MTNQKKLLLIDGSSVAFRAFFALYNQIDRFRNNSGLHTNAIYGFHLMLDNLLERIQPTHV  60
            M N++KLLLIDGSSVAFRAFFALYNQIDRF+N+SGLHTNAIYGFHLMLD+++ R++PTHV
Sbjct  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60

Query  61   LVAFDAGKTTFRTEMFADYKAGRAKTPEEFREQFPYIREMLAARGIAYYDLAQYEADDII  120
            LVAFDAGKTTFRTEM+ADYKAGRAKTP+EFREQF+YIREML+A GIAYY+L +YEADDII
Sbjct  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120

Query  121  GTLAKMAENTSEDYQITVVSGDKDLIQLTDENTVVEISKKGVAEFEAFTPDYLMEKMGIT  180
            GTL KMAE T   +++T+VSGDKDLIQLTDENTVVEISKKGVAEFE FTP YLMEKMG+T
Sbjct  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180

Query  181  PAQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLLEHGSLEGIYEHIDEMKKSKMKENLIN  240
            P QFIDLKALMGDKSDNIPGVTKIGEKTGLKLL E GSLEGIYEHID  K SKMKENLIN
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  241  DKEQAFLSKTLATIDTQSPIEIGLDDTAFTGPDLEKLAAFYDEMGFVQFKNALGGEAMPQ  300
            D++QAFLSKTLATI+T SPI IGLDD  + GPD+  L+ FYDEM+FVQ+K++L+++ MPQ
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQ-MPQ  299

Query  301  D--FDVAYAEPSQVTEAHFSSDDFFYFEILGDNYHTEPIIGFAWGNDKQIYASTDTDLLK  358
            +    ++Y E ++V+   FS++D+FYFE L DNYH E+IIGFAWG++ QIYASTD  LL 
Sbjct  300  EPVAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLA  359

Query  359  SEAFQAALSKAVNIYDFKRSKVLLSHLGIDLPTANFDARLAKYLLSTVEDNELSTIARLY  418
            +++F+  + K++  YDFKRSKVLLSHLGI+L ++++DARLA+YLLSTVEDNELSTIAR++
Sbjct  360  TDSFKQVFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIF  419

Query  419  TDLPLETDEVVYGKGAKRAVPEKEVLLSHlakkvkvlqvakpvMLEKLAEHGQSELLFDM  478
            TD++LE D+ VYGKGAKRAVP+K+VLL HLA+KVKVL  +K+ ML+KL+ H Q +L  ++
Sbjct  420  TDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNI  479

Query  479  ELPLANVLAKMEIAGIKVKGQTLNEMAVENQVVIDKLTQEIYEMAGEEFNINSPKQLGVI  538
            ELPLANVLAKMEI GIKV+  TL++MA +N+V+I+ LTQEIY+MAG+EFNINSPKQLG I
Sbjct  480  ELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSI  539

Query  539  LFEKMGLPLEYTKKTKTGYSTAVDVLERLAPIAPIVAKILEYRQITKLQSTYVLGLQDYI  598
            LFEKM LPLE TKKTKTGYSTAVDVLERLAPIAPIVAKIL+YRQITKLQSTYV+GLQDYI
Sbjct  540  LFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYI  599

Query  599  LEDGKIHTRYVQDLTQTGRLSSVDPNLQNIPVRLEQGRLIRKAFVPSTEDAVLLSSDYSQ  658
            L DGKIHTRYVQDLTQTGRLSSVDPNLQNIP+RLEQGRLIRKAF PS EDAVLLSSDYSQ
Sbjct  600  LADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQ  659

Query  659  IELRVLAHISGDEHLIAAFKEGADIHTSTAMRVFGIEKPEDVTPNDRRNAKAVNFGIVYG  718
            IELRVLAHISGDEHLIAAF+EGADIHTSTAMRVFGI+K+ DVT+NDRRNAKAVNFGIVYG
Sbjct  660  IELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYG  719

Query  719  ISDFGLSNNLGISRKKAKEYIDTYFERYPGIKAYMDNVVREAKDKGFVETLFHRRRELPD  778
            ISDFGLSNNLGI+RK++K YIDTYFERYPGIKAYM+NVVREAKDKG+VETLF RRRELPD
Sbjct  720  ISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPD  779

Query  779  INSRNFNVRNFAERTAINSPIQGSAADILKIAMINLDKALVEGGYKTKMLLQVHDEIVLE  838
            INSRNFNVR+FAERTAINSPIQGSAADILKIAMINLDKAL  GG+++KMLLQVHDEIVLE
Sbjct  780  INSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLE  839

Query  839  VPNDELVAMKALVKETMEAAVELAVPLIADENDGRTWYEAK  879
            VPNDEL A+K LVK+TMEAAV+LAVPL  DE+ G++WYEAK
Sbjct  840  VPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

33) polI in NC_013928


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score = 1169 bits (4433),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 673/880 (77%), Positives = 796/880 (91%), Gaps = 2/880 (0%)

Query  1    MTNKKKLLLIDGSSVAYRAFFALYNQIDRFKNPAGLHTNAIYGFHLMLDHMMKRVEPTHV  60
            M NK+KLLLIDGSSVA+RAFFALYNQIDRFKN +GLHTNAIYGFHLMLDHMMKRV PTHV
Sbjct  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60

Query  61   LVAFDAGKTTFRTEMFADYKAGRAKTPEEFREQLPYIREMLTALGVSYYDLENYEADDII  120
            LVAFDAGKTTFRTEM+ADYKAGRAKTP+EFREQ++YIREMLTALG++YY+LE+YEADDII
Sbjct  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120

Query  121  GTLDKLAENED-AYDVTIVSGDKDLIQLTDSNTTVEISKKGVAEFEEFTPDYLMEKMGLT  179
            GTLDK+AE  + ++DVTIVSGDKDLIQLTD NT VEISKKGVAEFEEFTP YLMEKMGLT
Sbjct  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180

Query  180  PKQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEHGSLEAIYEHIDSFKTTKMKENLIN  239
            P+QFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHE GSLE+IYEHID+FKT+KMKENLIN
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  240  DKEKAFLSKTLATIDTQAPITITLDDIDYSGPQLDALVKFYDEMDFRQFRSQLDSSSKAE  299
            D+++AFLSKTLATI+T +PITI LDDI Y+GP++ +L +FYDEMDF Q++  L S    E
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQE  300

Query  300  NFEV-SYTEVTELKPDMFAPDQFFYFEILNDNYHTQEMIGLAWGDDQAIYATTDTSLLTH  358
               V SY EVT++ +D+F+++++FYFE L DNYH + +IG+AWG+++ IYA+TD SLL+ 
Sbjct  301  PVAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLAT  360

Query  359  DLFKEALSKPIKTYDFKRGKVLLSHLGIDLLTASFDSRLAKYLLSTVENNNISTIARLYT  418
            D FK+ + KPI TYDFKR+KVLLSHLGI+L+++S+D+RLA+YLLSTVE+N++STIAR++T
Sbjct  361  DSFKQVFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIFT  420

Query  419  DLPLETDDDVYGKGAKRAIPEKNVLLSHLAKKISVLLASEEPMRQKLSANDQLDLLFEME  478
            D++LE DD VYGKGAKRA+P+K+VLL HLA+K+ VLL S   M +KL+A++QLDL  ++E
Sbjct  421  DISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNIE  480

Query  479  LPLANVLAKMEIAGISVRKETLQDMERANEIELQALTQEIYDLAGEAFNINSPKQLGVIL  538
            LPLANVLAKMEI GI V + TLQDM   N + ++ALTQEIYD+AG+ FNINSPKQLG IL
Sbjct  481  LPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSIL  540

Query  539  FEKLGLPLSATKKTKTGYSTAVDVLERLAHRSPIVAKILEYRQIAKLQSTYIIGLQDSIS  598
            FEK+ LPL  TKKTKTGYSTAVDVLERLA  +PIVAKIL+YRQI+KLQSTY+IGLQD I 
Sbjct  541  FEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYIL  600

Query  599  FDGKIHTRYLQDLTQTGRLSSVDPNLQNIPVRLEQGRLIRKAFVPEWKESVLLSSDYSQI  658
             DGKIHTRY+QDLTQTGRLSSVDPNLQNIP+RLEQGRLIRKAF P   ++VLLSSDYSQI
Sbjct  601  ADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQI  660

Query  659  ELRVLAHISGDEHLIAAFKEGADIHTSTAMRVFGIERPEDVTPNDRRNAKAVNFGVVYGI  718
            ELRVLAHISGDEHLIAAF+EGADIHTSTAMRVFGI+++ DVT+NDRRNAKAVNFG+VYGI
Sbjct  661  ELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGI  720

Query  719  SDFGLANNLGISRKAAKNYIETYFERYPGIKNYMDRVVREARDKGYVETLFHRRRELPDI  778
            SDFGL+NNLGI+RK +K+YI+TYFERYPGIK YM+ VVREA+DKGYVETLF RRRELPDI
Sbjct  721  SDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDI  780

Query  779  NSRNFNIRSFAERTAINSPIQGSAADILKVAMIHLDQALKKGDYQSRMLLQVHDEIVLEV  838
            NSRNFN+RSFAERTAINSPIQGSAADILK+AMI+LD+AL+ G+++++MLLQVHDEIVLEV
Sbjct  781  NSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEV  840

Query  839  PNAELEAIQKLVKETMESAIELSVPLVADENAGQTWYEAK  878
            PN EL AI+KLVK+TME+A++L+VPL  DE++GQ+WYEAK
Sbjct  841  PNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

34) polI in NC_004350


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score = 1168 bits (4429),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 673/880 (77%), Positives = 795/880 (91%), Gaps = 2/880 (0%)

Query  1    MTNKKKLLLIDGSSVAYRAFFALYNQIDRFKNPAGLHTNAIYGFHLMLDHMMKRVEPTHV  60
            M NK+KLLLIDGSSVA+RAFFALYNQIDRFKN +GLHTNAIYGFHLMLDHMMKRV PTHV
Sbjct  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60

Query  61   LVAFDAGKTTFRTEMFADYKAGRAKTPEEFREQLPYIREMLTALGVSYYDLENYEADDII  120
            LVAFDAGKTTFRTEM+ADYKAGRAKTP+EFREQ++YIREMLTALG++YY+LE+YEADDII
Sbjct  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120

Query  121  GTLDKLAENED-EYDVTIVSGDKDLIQLTDSNTTVEISKKGVAEFEEFTPDYLMEKMGLT  179
            GTLDK+AE  +  +DVTIVSGDKDLIQLTD NT VEISKKGVAEFEEFTP YLMEKMGLT
Sbjct  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180

Query  180  PKQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEHGSLEAIYEHIDSFKTTKMKENLIN  239
            P+QFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHE GSLE+IYEHID+FKT+KMKENLIN
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  240  DKEKAFLSKTLATIDTQAPITITLDDIDYSGPQLDALAKFYDEMDFRQFRSQLDSSPKTE  299
            D+++AFLSKTLATI+T +PITI LDDI Y+GP++ +L++FYDEMDF Q++  L S    E
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQE  300

Query  300  NFEV-SYTEVTELKPDMFAPDQFFYFEILNDNYHTQEMIGLAWGDDQAIYATTDTSLLTH  358
               V SY EVT++ +D+F+++++FYFE L DNYH + +IG+AWG+++ IYA+TD SLL+ 
Sbjct  301  PVAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLAT  360

Query  359  DLFKEALSKPIKTYDFKRGKVLLSHLGIDLPTASFDSRLAKYLLSTVENNNISTIARLYT  418
            D FK+ + KPI TYDFKR+KVLLSHLGI+L ++S+D+RLA+YLLSTVE+N++STIAR++T
Sbjct  361  DSFKQVFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIFT  420

Query  419  DLPLETDDDVYGKGAKRAIPEKNVLLSHLAKKISVLLASEEPMRQKLSANDQLDLLFEME  478
            D++LE DD VYGKGAKRA+P+K+VLL HLA+K+ VLL S   M +KL+A++QLDL  ++E
Sbjct  421  DISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNIE  480

Query  479  LPLANVLAKMEIAGISVRKETLQDMERANEIELQALTQEIYDLAGEAFNINSPKQLGVIL  538
            LPLANVLAKMEI GI V + TLQDM   N + ++ALTQEIYD+AG+ FNINSPKQLG IL
Sbjct  481  LPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSIL  540

Query  539  FEKLGLPLSATKKTKTGYSTAVDVLERLAHRSPIVAKILEYRQIAKLQSTYIIGLQDSIS  598
            FEK+ LPL  TKKTKTGYSTAVDVLERLA  +PIVAKIL+YRQI+KLQSTY+IGLQD I 
Sbjct  541  FEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYIL  600

Query  599  FDGKIHTRYLQDLTQTGRLSSVDPNLQNIPVRLEQGRLIRKAFVPEWKESVLLSSDYSQI  658
             DGKIHTRY+QDLTQTGRLSSVDPNLQNIP+RLEQGRLIRKAF P   ++VLLSSDYSQI
Sbjct  601  ADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQI  660

Query  659  ELRVLAHISGDEHLIAAFKEGADIHTSTAMRVFGIERPEDVTPNDRRNAKAVNFGVVYGI  718
            ELRVLAHISGDEHLIAAF+EGADIHTSTAMRVFGI+++ DVT+NDRRNAKAVNFG+VYGI
Sbjct  661  ELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGI  720

Query  719  SDFGLANNLGISRKAAKNYIETYFERYPGIKNYMDRVVREARDKGYVETLFHRRRELPDI  778
            SDFGL+NNLGI+RK +K+YI+TYFERYPGIK YM+ VVREA+DKGYVETLF RRRELPDI
Sbjct  721  SDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDI  780

Query  779  NSRNFNIRSFAERTAINSPIQGSAADILKVAMIHLDQALKKGDYQSRMLLQVHDEIVLEV  838
            NSRNFN+RSFAERTAINSPIQGSAADILK+AMI+LD+AL+ G+++++MLLQVHDEIVLEV
Sbjct  781  NSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEV  840

Query  839  PNAELEAIQKLVKETMESAIELSVPLVADENAGQTWYEAK  878
            PN EL AI+KLVK+TME+A++L+VPL  DE++GQ+WYEAK
Sbjct  841  PNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

35) SMUGS5_01195 in NC_018089


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score = 1166 bits (4424),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 672/880 (77%), Positives = 795/880 (91%), Gaps = 2/880 (0%)

Query  1    MTNKKKLLLIDGSSVAYRAFFALYNQIDRFKNPAGLHTNAIYGFHLMLDHMMKRVEPTHV  60
            M NK+KLLLIDGSSVA+RAFFALYNQIDRFKN +GLHTNAIYGFHLMLDHMMKRV PTHV
Sbjct  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60

Query  61   LVAFDAGKTTFRTEMFADYKAGRAKTPEEFREQLPYIREMLTALGVSYYDLENYEADDII  120
            LVAFDAGKTTFRTEM+ADYKAGRAKTP+EFREQ++YIREMLTALG++YY+LE+YEADDII
Sbjct  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120

Query  121  GTLDKLAENED-EYDVTIVSGDKDLIQLTDSNTTVEISKKGVAEFEEFTPDYLMEKMGLT  179
            GTLDK+AE  +  +DVTIVSGDKDLIQLTD NT VEISKKGVAEFEEFTP YLMEKMGLT
Sbjct  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180

Query  180  PKQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEHGSLEAIYEHIDSFKTTKMKENLIN  239
            P+QFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHE GSLE+IYEHID+FKT+KMKENLIN
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  240  DKEKAFLSKTLATIDTQAPITITLDDIDYSGPQLDALAKFYDEMDFRQFRSQLDSSSKSE  299
            D+++AFLSKTLATI+T +PITI LDDI Y+GP++ +L++FYDEMDF Q++  L S    E
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQE  300

Query  300  NFEV-SYTEVTELKPDMFAPDQFFYFEILNDNYHTQEMIGLAWGDDQAIYATTDTSLLTH  358
               V SY EVT++ +D+F+++++FYFE L DNYH + +IG+AWG+++ IYA+TD SLL+ 
Sbjct  301  PVAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLAT  360

Query  359  DLFKEALSKPIKTYDFKRGKVLLSHLGLDLPTASFDSRLAKYLLSTVENNNISTIARLYT  418
            D FK+ + KPI TYDFKR+KVLLSHLG++L ++S+D+RLA+YLLSTVE+N++STIAR++T
Sbjct  361  DSFKQVFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIFT  420

Query  419  DLPLETDDDVYGKGAKRAIPEKNVLLSHLAKKISVLLASEEPMRQKLSANDQLDLLFEME  478
            D++LE DD VYGKGAKRA+P+K+VLL HLA+K+ VLL S   M +KL+A++QLDL  ++E
Sbjct  421  DISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNIE  480

Query  479  LPLANVLAKMEIAGISVRKETLQDMERANEIELQALTQEIYDLAGEAFNINSPKQLGVIL  538
            LPLANVLAKMEI GI V + TLQDM   N + ++ALTQEIYD+AG+ FNINSPKQLG IL
Sbjct  481  LPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSIL  540

Query  539  FEKLGLPLSATKKTKTGYSTAVDVLERLAHRSPIVAKILEYRQIAKLQSTYIIGLQDSIS  598
            FEK+ LPL  TKKTKTGYSTAVDVLERLA  +PIVAKIL+YRQI+KLQSTY+IGLQD I 
Sbjct  541  FEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYIL  600

Query  599  FDGKIHTRYLQDLTQTGRLSSVDPNLQNIPVRLEQGRLIRKAFVPEWKESVLLSSDYSQI  658
             DGKIHTRY+QDLTQTGRLSSVDPNLQNIP+RLEQGRLIRKAF P   ++VLLSSDYSQI
Sbjct  601  ADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQI  660

Query  659  ELRVLAHISGDEHLIAAFKEGADIHTSTAMRVFGIERPEDVTPNDRRNAKAVNFGVVYGI  718
            ELRVLAHISGDEHLIAAF+EGADIHTSTAMRVFGI+++ DVT+NDRRNAKAVNFG+VYGI
Sbjct  661  ELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGI  720

Query  719  SDFGLANNLGISRKAAKNYIETYFERYPGIKNYMDRVVREARDKGYVETLFHRRRELPDI  778
            SDFGL+NNLGI+RK +K+YI+TYFERYPGIK YM+ VVREA+DKGYVETLF RRRELPDI
Sbjct  721  SDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDI  780

Query  779  NSRNFNIRSFAERTAINSPIQGSAADILKVAMIHLDQALKKGDYQSRMLLQVHDEIVLEV  838
            NSRNFN+RSFAERTAINSPIQGSAADILK+AMI+LD+AL+ G+++++MLLQVHDEIVLEV
Sbjct  781  NSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEV  840

Query  839  PNAELEAIQKLVKETMESAIELSVPLVADENAGQTWYEAK  878
            PN EL AI+KLVK+TME+A++L+VPL  DE++GQ+WYEAK
Sbjct  841  PNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

36) polI in NC_017768


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score = 1165 bits (4419),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 672/880 (77%), Positives = 794/880 (91%), Gaps = 2/880 (0%)

Query  1    MTNKKKLLLIDGSSVAYRAFFALYNQIDRFKNPAGLHTNAIYGFHLMLDHMMKRVEPTHV  60
            M NK+KLLLIDGSSVA+RAFFALYNQIDRFKN +GLHTNAIYGFHLMLDHMMKRV PTHV
Sbjct  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60

Query  61   LVAFDAGKTTFRTEMFADYKAGRAKTPEEFREQLPYIREMLTALGVSYYDLENYEADDII  120
            LVAFDAGKTTFRTEM+ADYKAGRAKTP+EFREQ++YIREMLTALG++YY+LE+YEADDII
Sbjct  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120

Query  121  GTLDKLAENED-EYDVTIVSGDKDLIQLTDSNTTVEISKKGVAEFEEFTPDYLMEKMGLT  179
            GTLDK+AE  +  +DVTIVSGDKDLIQLTD NT VEISKKGVAEFEEFTP YLMEKMGLT
Sbjct  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180

Query  180  PKQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEHGSLEAIYEHIDSFKTTKMKKNLIN  239
            P+QFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHE GSLE+IYEHID+FKT+KMK NLIN
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  240  DKEKAFLSKTLATIDTQAPITITLDDIDYSGPQLDALAKFYDEMDFRQFRSQLDSSPKAE  299
            D+++AFLSKTLATI+T +PITI LDDI Y+GP++ +L++FYDEMDF Q++  L S    E
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQE  300

Query  300  NFEV-SYTEVTELKPDMFAPDQFFYFEILNDNYHTQEMIGLAWGDDQAIYATTDTSLLTH  358
               V SY EVT++ +D+F+++++FYFE L DNYH + +IG+AWG+++ IYA+TD SLL+ 
Sbjct  301  PVAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLAT  360

Query  359  DLFKEALSKPIKTYDFKRGKVLLSHLGIDLPTASFDSRLAKYLLSTVENNNISTIARLYT  418
            D FK+ + KPI TYDFKR+KVLLSHLGI+L ++S+D+RLA+YLLSTVE+N++STIAR++T
Sbjct  361  DSFKQVFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIFT  420

Query  419  DLPLETDDDVYGKGAKRAIPEKNVLLSHLAKKISVLLASEEPMCQKLSANDQLDLLFEME  478
            D++LE DD VYGKGAKRA+P+K+VLL HLA+K+ VLL S   M +KL+A++QLDL  ++E
Sbjct  421  DISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNIE  480

Query  479  LPLANVLAKMEIAGISVRKETLQDMERANEIELQALTQEIYDLAGEAFNINSPKQLGVIL  538
            LPLANVLAKMEI GI V + TLQDM   N + ++ALTQEIYD+AG+ FNINSPKQLG IL
Sbjct  481  LPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSIL  540

Query  539  FEKLGLPLSATKKTKTGYSTAVDVLERLAHRSPIVAKILEYRQIAKLQSTYIIGLQDSIS  598
            FEK+ LPL  TKKTKTGYSTAVDVLERLA  +PIVAKIL+YRQI+KLQSTY+IGLQD I 
Sbjct  541  FEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYIL  600

Query  599  FDGKIHTRYLQDLTQTGRLSSVDPNLQNIPVRLEQGRLIRKAFVPEWKESVLLSSDYSQI  658
             DGKIHTRY+QDLTQTGRLSSVDPNLQNIP+RLEQGRLIRKAF P   ++VLLSSDYSQI
Sbjct  601  ADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQI  660

Query  659  ELRVLAHISGDEHLIAAFKEGADIHTSTAMRVFGIERPEDVTPNDRRNAKAVNFGVVYGI  718
            ELRVLAHISGDEHLIAAF+EGADIHTSTAMRVFGI+++ DVT+NDRRNAKAVNFG+VYGI
Sbjct  661  ELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGI  720

Query  719  SDFGLANNLGISRKAAKNYIETYFERYPGIKNYMDRVVREARDKGYVETLFHRRRELPDI  778
            SDFGL+NNLGI+RK +K+YI+TYFERYPGIK YM+ VVREA+DKGYVETLF RRRELPDI
Sbjct  721  SDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDI  780

Query  779  NSRNFNIRSFAERTAINSPIQGSAADILKVAMIHLDQALKKGDYQSRMLLQVHDEIVLEV  838
            NSRNFN+RSFAERTAINSPIQGSAADILK+AMI+LD+AL+ G+++++MLLQVHDEIVLEV
Sbjct  781  NSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEV  840

Query  839  PNAELEAIQKLVKETMESAIELSVPLVADENAGQTWYEAK  878
            PN EL AI+KLVK+TME+A++L+VPL  DE++GQ+WYEAK
Sbjct  841  PNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

37) polA in NC_015678


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score = 1163 bits (4411),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 667/881 (76%), Positives = 790/881 (90%), Gaps = 1/881 (0%)

Query  1    MEKKNKLLLIDGSSVAFRAFFALYHQIDRFKNANGLHTNAVYGFNLMLSHLLERIQPTHV  60
            ME+KNKLLLIDGSSVAFRAFFALY+QIDRFKN +GLHTNA+YGF+LML H++ R++PTHV
Sbjct  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60

Query  61   LVAFDAGKTTFRTEMYADYKGGRAKTPDEFREQFPFIREQLDHLGIRHYELAQYEADDII  120
            LVAFDAGKTTFRTEMYADYK+GRAKTPDEFREQF++IRE L  LGI  YEL +YEADDII
Sbjct  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120

Query  121  GTLDKMAETTSVPFDVTIVSGDKDLIQLTDDNTVVEISKKGVAEFEEFTPAYLKEKMGLT  180
            GTLDKMAE T VPFDVTIVSGDKDLIQLTD+NTVVEISKKGVAEFEEFTPAYL EKMGLT
Sbjct  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180

Query  181  PEQFIDLKALMGDKSDNIPGVTKIGEKTGIKLLLKYGSLDGIYEHIDEMKASKMKENLIN  240
            P+QFIDLKALMGDKSDNIPGVTKIGEKTG+KLL  +GSL+GIYEHID  K+SKMKENLIN
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  241  DKEQAYLSKTLATIDTNAPIEIGLDDITYTGPHLENLAKFYEEMGFKQLRQALDLSGEEA  300
            D++QA+LSKTLATI+T +PI IGLDDI Y GP++ +L++FY+EM+F QL+++L     + 
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQE  300

Query  301  APVAIDYTEVEQVASDMLTEDSFFHFEIFGDNYHTEPIIGFAWGTKGQLYASTDTGLLQT  360
            +   I Y EV +V++D+++ + +F FE + DNYH E+IIGFAWG   Q+YASTD +LL T
Sbjct  301  PVAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLAT  360

Query  361  PIFKEFLEKTPLKVYDFKRAKVLLSHLGITLQNPAFDSRLAKYLLSTVEDNEISTIASLY  420
              FK+ ++K P+  YDFKR+KVLLSHLGI L  P++D+RLA+YLLSTVEDNE+STIA ++
Sbjct  361  DSFKQVFQK-PIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIF  419

Query  421  SQIALPLDEVVYGKGVKRAIPERAVLLEHLALKVAVLLDTEEPMVEQLQAHDQLDLLYDM  480
            ++I+L  D+ VYGKG KRA+P++ VLLEHLA KV VLLD+   M+++L AH+QLDL  ++
Sbjct  420  TDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNI  479

Query  481  EQPLAAVLAKMEIAGIKVERQTLEDMQVENEVVLERLTQEIYELAGEEFNINSPKQLGVI  540
            E PLA VLAKMEI GIKV+R TL+DM  +N V++E LTQEIY++AG+EFNINSPKQLG I
Sbjct  480  ELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSI  539

Query  541  LFEKLELPLEYTKKTKTGYSTAVDVLERLAPIAPIVSKILEYRQIAKIQSTYVIGLQDWI  600
            LFEK++LPLE TKKTKTGYSTAVDVLERLAPIAPIV+KIL+YRQI+K+QSTYVIGLQD I
Sbjct  540  LFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYI  599

Query  601  LEDGKIHTRYVQDLTQTGRLSSVDPNLQNIPVRLEQGRLIRKAFVPEEENSVLLSSDYSQ  660
            L DGKIHTRYVQDLTQTGRLSSVDPNLQNIP+RLEQGRLIRKAF P +E++VLLSSDYSQ
Sbjct  600  LADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQ  659

Query  661  IELRVLAHISGDEHLIDAFKHGADIHTSTAMRVFNIEKPEDVTPNDRRNAKAVNFGVVYG  720
            IELRVLAHISGDEHLI AF++GADIHTSTAMRVF I+K+ DVT+NDRRNAKAVNFG+VYG
Sbjct  660  IELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYG  719

Query  721  ISDFGLSNNLGISRKEAKAYIETYFERYPGIKDYMERVVREARDKGYVETLFKRRREIPD  780
            ISDFGLSNNLGI+RK++K+YI+TYFERYPGIK YME VVREA+DKGYVETLFKRRRE+PD
Sbjct  720  ISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPD  779

Query  781  INSRNFNVRGFAERTAINSPIQGSAADILKIAMIHLDQALEAGAYKTKMLLQVHDEIVLQ  840
            INSRNFNVR+FAERTAINSPIQGSAADILKIAMI+LD+AL+AG++++KMLLQVHDEIVL+
Sbjct  780  INSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLE  839

Query  841  VPSDELAAIKELVKETMESAIELAVPLEADENEGKTWYEAK  881
            VP+DEL+AIK LVK+TME+A++LAVPL  DE+ G++WYEAK
Sbjct  840  VPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

38) polA in NC_017905


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score = 1163 bits (4412),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 666/881 (76%), Positives = 791/881 (90%), Gaps = 1/881 (0%)

Query  14   MEKKNKLLLIDGSSVAFRAFFALYHQIDRFKNSNGLHTNAVYGFNLMLSHLLERIQPTHV  73
            ME+KNKLLLIDGSSVAFRAFFALY+QIDRFKN +GLHTNA+YGF+LML H++ R++PTHV
Sbjct  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60

Query  74   LVAFDAGKTTFRTEMYADYKGGRAKTPDEFREQFPFIREQLDHLGIRHYELAQYEADDII  133
            LVAFDAGKTTFRTEMYADYK+GRAKTPDEFREQF++IRE L  LGI  YEL +YEADDII
Sbjct  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120

Query  134  GTLDKMAEATSVPFEVTIVSGDKDLIQLTDDNTVVEISKKGVAEFEEFTPAYLKEKMGLT  193
            GTLDKMAE T VPF+VTIVSGDKDLIQLTD+NTVVEISKKGVAEFEEFTPAYL EKMGLT
Sbjct  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180

Query  194  PEQFIDLKALMGDKSDNIPGVTKIGEKTGIKLLLEYGSLDGIYEHIDEMKASKMKENLIN  253
            P+QFIDLKALMGDKSDNIPGVTKIGEKTG+KLL E+GSL+GIYEHID  K+SKMKENLIN
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  254  DKEQAYLSKTLATIDTNAPIEIGLDDITYTGPHLENLAEFYEEMGFKQLRQALDLSGEEA  313
            D++QA+LSKTLATI+T +PI IGLDDI Y GP++ +L++FY+EM+F QL+++L     + 
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQE  300

Query  314  APVVIDYTEVEQVTSDMLTEDSFFHFEIFGDNYHTEPIIGFAWGTKGQLYASTDTGLLQT  373
            +  VI Y EV +V++D+++ + +F FE + DNYH E+IIGFAWG   Q+YASTD +LL T
Sbjct  301  PVAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLAT  360

Query  374  PIFKEFLEKTPLKVYDFKRAKVLLSHLGITLQNPAFDSRLAKYLLSTVEDNEISTIASLY  433
              FK+ ++K P+  YDFKR+KVLLSHLGI L  P++D+RLA+YLLSTVEDNE+STIA ++
Sbjct  361  DSFKQVFQK-PIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIF  419

Query  434  SQIALPLDEVVYGKGAKKTIPEKTALLEHLARKVAVLLDTEEPMIEQLQAHDQLDLLYDM  493
            ++I+L  D+ VYGKGAK+++P+K  LLEHLARKV VLLD+   M+++L AH+QLDL  ++
Sbjct  420  TDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNI  479

Query  494  EQPLAAVLAKMEIAGIKVERQTLEDMQVENEVVLERLTQEIYELAGEEFNINSPKQLGVI  553
            E PLA VLAKMEI GIKV+R TL+DM  +N V++E LTQEIY++AG+EFNINSPKQLG I
Sbjct  480  ELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSI  539

Query  554  LFEKLELPLEYTKKTKTGYSTAVDVLGRLAPIAPIVSKILEYRQIAKIQSTYVIGLQDWI  613
            LFEK++LPLE TKKTKTGYSTAVDVL RLAPIAPIV+KIL+YRQI+K+QSTYVIGLQD I
Sbjct  540  LFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYI  599

Query  614  LEDGKIHTRYVQDLTQTGRLSSVDPNLQNIPVRLEQGRLIRKAFVPEEENSVLLSSDYSQ  673
            L DGKIHTRYVQDLTQTGRLSSVDPNLQNIP+RLEQGRLIRKAF P +E++VLLSSDYSQ
Sbjct  600  LADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQ  659

Query  674  IELRVLAHISGDEHLIDAFKHGADIHTSTAMRVFNIEKPEDVTPNDRRNAKAVNFGVVYG  733
            IELRVLAHISGDEHLI AF++GADIHTSTAMRVF I+K+ DVT+NDRRNAKAVNFG+VYG
Sbjct  660  IELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYG  719

Query  734  ISDFGLSNNLGISRKEAKAYIETYFERYPGIKDYMERVVREARDKGYVETLFKRRREIPD  793
            ISDFGLSNNLGI+RK++K+YI+TYFERYPGIK YME VVREA+DKGYVETLFKRRRE+PD
Sbjct  720  ISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPD  779

Query  794  INSRNFNVRGFAERTAINSPIQGSAADILKIAMIHLDQALERGAYKTKMLLQVHDEIVLQ  853
            INSRNFNVR+FAERTAINSPIQGSAADILKIAMI+LD+AL+ G++++KMLLQVHDEIVL+
Sbjct  780  INSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLE  839

Query  854  VPSDELAAIKELVKETMESAIELAVPLEADENEGKTWYEAK  894
            VP+DEL+AIK LVK+TME+A++LAVPL  DE+ G++WYEAK
Sbjct  840  VPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

39) STER_1736 in NC_008532


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score = 1160 bits (4398),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 685/880 (78%), Positives = 795/880 (91%), Gaps = 1/880 (0%)

Query  1    MTNQKKLLLIDGSSVAFRAFFALYNQIDRFRNNNGLHTNAIYGFHLMLDNLLERIQPTHV  60
            M N++KLLLIDGSSVAFRAFFALYNQIDRF+N++GLHTNAIYGFHLMLD+++ R++PTHV
Sbjct  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60

Query  61   LVAFDAGKTTFRTEMFADYKAGRAKTPEEFREQLPYIREMLAARGIAYYDLAQYEADDII  120
            LVAFDAGKTTFRTEM+ADYKAGRAKTP+EFREQ++YIREML+A GIAYY+L +YEADDII
Sbjct  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120

Query  121  GTLAKMAENTSEAFQITVVSGDKDLIQLTDENTVVEISKKGVAEFEAFTPDYLMEKMGIT  180
            GTL KMAE T  +F++T+VSGDKDLIQLTDENTVVEISKKGVAEFE FTP YLMEKMG+T
Sbjct  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180

Query  181  PAQFVDLKALMGDKSDNIPGVTKIGEKTGLKLLLEHGSLEGIYDHIDEMKKSKMKENLIN  240
            P QF+DLKALMGDKSDNIPGVTKIGEKTGLKLL E GSLEGIY+HID  K SKMKENLIN
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  241  DKEQAFLSKTLATIDTQSPIEIGLDDTAFKGPNLEKLLAFYDEMGFVHFKNALRGEAVPQ  300
            D++QAFLSKTLATI+T SPI IGLDD  ++GP++  L  FYDEM+FV++K++L ++   +
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQE  300

Query  301  DFDV-AYVEPSQVTADHFSSEDFFYFEILGDNYHTEPIIGFAWGNEKQIYASTDTDLLKS  359
               V +Y E ++V+AD FS+ED+FYFE L DNYH E+IIGFAWG+  QIYASTD  LL +
Sbjct  301  PVAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLAT  360

Query  360  EAFQAALSKAVNIYDFKRSKVLLSHLGIDLPTANFDARLAKYLLSTVEDNELSTIARLYT  419
            ++F+  + K++  YDFKRSKVLLSHLGI+L ++++DARLA+YLLSTVEDNELSTIAR++T
Sbjct  361  DSFKQVFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIFT  420

Query  420  DLPLETDEVVYGKGAKRAIPEKEVLLSHlakkvkvlqvakpvMLEKLAEHGQSELLFDME  479
            D++LE D+ VYGKGAKRA+P+K+VLL HLA+KVKVL  +K+ ML+KL+ H Q +L  ++E
Sbjct  421  DISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNIE  480

Query  480  LPLANVLAKMEMAGIKVDGQTLNEMAVENQAVIDKLTQDIYEMAGEEFNINSPKQLGVIL  539
            LPLANVLAKME+ GIKV+  TL++MA +N+ +I+ LTQ+IY+MAG+EFNINSPKQLG IL
Sbjct  481  LPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSIL  540

Query  540  FEKMGLPLEYTKKTKTGYSTAVDVLERLAPIAPIVAKILEYRQITKLQSTYVLGLQDYIL  599
            FEKM LPLE TKKTKTGYSTAVDVLERLAPIAPIVAKIL+YRQITKLQSTYV+GLQDYIL
Sbjct  541  FEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYIL  600

Query  600  EDGKIHTRYMQDLTQTGRLSSVDPNLQNIPVRLEQGRLIRKAFVPSTKDAVLLSSDYSQI  659
             DGKIHTRY+QDLTQTGRLSSVDPNLQNIP+RLEQGRLIRKAF PS  DAVLLSSDYSQI
Sbjct  601  ADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQI  660

Query  660  ELRVLAHISGDEHLIAAFKEGADIHTSTAMRVFGIEKPEDVTPNDRRNAKAVNFGIVYGI  719
            ELRVLAHISGDEHLIAAF+EGADIHTSTAMRVFGI+K+ DVT+NDRRNAKAVNFGIVYGI
Sbjct  661  ELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGI  720

Query  720  SDFGLSNNLGISRKKAKEYIDTYFERYPGIKAYMDNVVREAKDKGYVSTLFHRRRELPDI  779
            SDFGLSNNLGI+RK++K YIDTYFERYPGIKAYM+NVVREAKDKGYV TLF RRRELPDI
Sbjct  721  SDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDI  780

Query  780  NSRNFNVRNFAERTAINSPIQGSAADILKIAMINLDKALVEGGYKTKMLLQVHDEIVLEV  839
            NSRNFNVR+FAERTAINSPIQGSAADILKIAMINLDKAL  GG+++KMLLQVHDEIVLEV
Sbjct  781  NSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEV  840

Query  840  PSDELLAMKALVKETMESAVELAVPLIADENEGCTWYEAK  879
            P+DEL A+K LVK+TME+AV+LAVPL  DE+ G +WYEAK
Sbjct  841  PNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

40) STND_1696 in NC_017563


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score = 1160 bits (4398),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 685/880 (78%), Positives = 795/880 (91%), Gaps = 1/880 (0%)

Query  1    MTNQKKLLLIDGSSVAFRAFFALYNQIDRFRNNNGLHTNAIYGFHLMLDNLLERIQPTHV  60
            M N++KLLLIDGSSVAFRAFFALYNQIDRF+N++GLHTNAIYGFHLMLD+++ R++PTHV
Sbjct  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60

Query  61   LVAFDAGKTTFRTEMFADYKAGRAKTPEEFREQLPYIREMLAARGIAYYDLAQYEADDII  120
            LVAFDAGKTTFRTEM+ADYKAGRAKTP+EFREQ++YIREML+A GIAYY+L +YEADDII
Sbjct  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120

Query  121  GTLAKMAENTSEAFQITVVSGDKDLIQLTDENTVVEISKKGVAEFEAFTPDYLMEKMGIT  180
            GTL KMAE T  +F++T+VSGDKDLIQLTDENTVVEISKKGVAEFE FTP YLMEKMG+T
Sbjct  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180

Query  181  PAQFVDLKALMGDKSDNIPGVTKIGEKTGLKLLLEHGSLEGIYDHIDEMKKSKMKENLIN  240
            P QF+DLKALMGDKSDNIPGVTKIGEKTGLKLL E GSLEGIY+HID  K SKMKENLIN
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  241  DKEQAFLSKTLATIDTQSPIEIGLDDTAFKGPNLEKLLAFYDEMGFVHFKNALRGEAVPQ  300
            D++QAFLSKTLATI+T SPI IGLDD  ++GP++  L  FYDEM+FV++K++L ++   +
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQE  300

Query  301  DFDV-AYVEPSQVTADHFSSEDFFYFEILGDNYHTEPIIGFAWGNEKQIYASTDTDLLKS  359
               V +Y E ++V+AD FS+ED+FYFE L DNYH E+IIGFAWG+  QIYASTD  LL +
Sbjct  301  PVAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLAT  360

Query  360  EAFQAALSKAVNIYDFKRSKVLLSHLGIDLPTANFDARLAKYLLSTVEDNELSTIARLYT  419
            ++F+  + K++  YDFKRSKVLLSHLGI+L ++++DARLA+YLLSTVEDNELSTIAR++T
Sbjct  361  DSFKQVFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIFT  420

Query  420  DLPLETDEVVYGKGAKRAIPEKEVLLSHlakkvkvlqvakpvMLEKLAEHGQSELLFDME  479
            D++LE D+ VYGKGAKRA+P+K+VLL HLA+KVKVL  +K+ ML+KL+ H Q +L  ++E
Sbjct  421  DISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNIE  480

Query  480  LPLANVLAKMEMAGIKVDGQTLNEMAVENQAVIDKLTQDIYEMAGEEFNINSPKQLGVIL  539
            LPLANVLAKME+ GIKV+  TL++MA +N+ +I+ LTQ+IY+MAG+EFNINSPKQLG IL
Sbjct  481  LPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSIL  540

Query  540  FEKMGLPLEYTKKTKTGYSTAVDVLERLAPIAPIVAKILEYRQITKLQSTYVLGLQDYIL  599
            FEKM LPLE TKKTKTGYSTAVDVLERLAPIAPIVAKIL+YRQITKLQSTYV+GLQDYIL
Sbjct  541  FEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYIL  600

Query  600  EDGKIHTRYMQDLTQTGRLSSVDPNLQNIPVRLEQGRLIRKAFVPSTKDAVLLSSDYSQI  659
             DGKIHTRY+QDLTQTGRLSSVDPNLQNIP+RLEQGRLIRKAF PS  DAVLLSSDYSQI
Sbjct  601  ADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQI  660

Query  660  ELRVLAHISGDEHLIAAFKEGADIHTSTAMRVFGIEKPEDVTPNDRRNAKAVNFGIVYGI  719
            ELRVLAHISGDEHLIAAF+EGADIHTSTAMRVFGI+K+ DVT+NDRRNAKAVNFGIVYGI
Sbjct  661  ELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGI  720

Query  720  SDFGLSNNLGISRKKAKEYIDTYFERYPGIKAYMDNVVREAKDKGYVSTLFHRRRELPDI  779
            SDFGLSNNLGI+RK++K YIDTYFERYPGIKAYM+NVVREAKDKGYV TLF RRRELPDI
Sbjct  721  SDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDI  780

Query  780  NSRNFNVRNFAERTAINSPIQGSAADILKIAMINLDKALVEGGYKTKMLLQVHDEIVLEV  839
            NSRNFNVR+FAERTAINSPIQGSAADILKIAMINLDKAL  GG+++KMLLQVHDEIVLEV
Sbjct  781  NSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEV  840

Query  840  PSDELLAMKALVKETMESAVELAVPLIADENEGCTWYEAK  879
            P+DEL A+K LVK+TME+AV+LAVPL  DE+ G +WYEAK
Sbjct  841  PNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

41) polA in NC_017581


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score = 1159 bits (4395),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 685/880 (78%), Positives = 794/880 (91%), Gaps = 1/880 (0%)

Query  1    MTNQKKLLLIDGSSVAFRAFFALYNQIDRFRNNNGLHTNAIYGFHLMLDNLLERIQPTHV  60
            M N++KLLLIDGSSVAFRAFFALYNQIDRF+N++GLHTNAIYGFHLMLD+++ R++PTHV
Sbjct  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60

Query  61   LVAFDAGKTTFRTEMFADYKAGRAKTPEEFREQLPYIREMLAARGIAYYDLAQYEADDII  120
            LVAFDAGKTTFRTEM+ADYKAGRAKTP+EFREQ++YIREML+A GIAYY+L +YEADDII
Sbjct  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120

Query  121  GTLAKMAENTSEAFQITVVSGDKDLIQLTDENTVVEISKKGVAEFEAFTPDYLMEKMGIT  180
            GTL KMAE T  +F++T+VSGDKDLIQLTDENTVVEISKKGVAEFE FTP YLMEKMG+T
Sbjct  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180

Query  181  PAQFVDLKALMGDKSDNIPGVTKIGEKTGLKLLLEHGSLEGIYDHIDEMKKSKMKENLIN  240
            P QF+DLKALMGDKSDNIPGVTKIGEKTGLKLL E GSLEGIY+HID  K SKMKENLIN
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  241  DKEQAFLSKTLATIDTQSPIEIGLDDTAFKGPNLEKLLAFYDEMGFVHFKNALRGEAVPQ  300
            D++QAFLSKTLATI+T SPI IGLDD  ++GP++  L  FYDEM+FV++K++L ++   +
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQE  300

Query  301  DFDV-AYVEPSQVTADHFSSEDFFYFEILGDNYHTEPIIGFAWGNEKQIYASTDTDLLKS  359
               V +Y E ++V+AD FS+ED+FYFE L DNYH E+IIGFAWG+  QIYASTD  LL +
Sbjct  301  PVAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLAT  360

Query  360  EAFQAALSKAVNIYDFKRSKVLLSHLGIDLPTANFDARLAKYLLSTVEDNELSTIARLYT  419
            ++F+  + K++  YDFKRSKVLLSHLGI+L ++++DARLA+YLLSTVEDNELSTIAR++T
Sbjct  361  DSFKQVFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIFT  420

Query  420  DLPLETDEVVYGKGAKRAIPEKEVLLSHlakkvkvlqvakpvMLEKLAEHGQSELLFDME  479
            D++LE D+ VYGKGAKRA+P+K+VLL HLA+KVKVL  +K+ ML+KL+ H Q +L  ++E
Sbjct  421  DISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNIE  480

Query  480  LPLANVLAKMEMAGIKVDGQTLNEMAVENQAVIDKLTQDIYEMAGEEFNINSPKQLGVIL  539
            LPLANVLAKME+ GIKV+  TL++MA +N+ +I+ LTQ+IY+MAG+EFNINSPKQLG IL
Sbjct  481  LPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSIL  540

Query  540  FEKMGLPLEYTKKTKTGYSTAVDVLERLAPIAPIVAKILEYRQITKLQSTYVLGLQDYIL  599
            FEKM LPLE TKKTKTGYSTAVDVLERLAPIAPIVAKIL+YRQITKLQSTYV+GLQDYIL
Sbjct  541  FEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYIL  600

Query  600  EDGKIHTRYMQDLTQTGRLSSVDPNLQNIPVRLEQGRLIRKAFVPSTKDAVLLSSDYSQI  659
             DGKIHTRY+QDLTQTGRLSSVDPNLQNIP+RLEQGRLIRKAF PS  DAVLLSSDYSQI
Sbjct  601  ADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQI  660

Query  660  ELRVLAHISGDEHLIAAFKEGADIHTSTAMRVFGIEKPEDVTPNDRRNAKAVNFGIVYGI  719
            ELRVLAHISGDEHLIAAF+EGADIHTSTAMRVFGI+K+ DVT+NDRRNAKAVNFGIVYGI
Sbjct  661  ELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGI  720

Query  720  SDFGLSNNLGISRKKAKEYIDTYFERYPGIKAYMDNVVREAKDKGYVSTLFHRRRELPDI  779
            SDFGLSNNLGI+RK++K YIDTYFERYPGIKAYM+NVVREAKDKGYV TLF RRRELPDI
Sbjct  721  SDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDI  780

Query  780  NSRNFNVRNFAERTAINSPIQGSAADILKIAMINLDKALVEGGYKTKMLLQVHDEIILEV  839
            NSRNFNVR+FAERTAINSPIQGSAADILKIAMINLDKAL  GG+++KMLLQVHDEI+LEV
Sbjct  781  NSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEV  840

Query  840  PRDELLAMKALVKETMEAAVELAVPLIADENEGCTWYEAK  879
            P DEL A+K LVK+TMEAAV+LAVPL  DE+ G +WYEAK
Sbjct  841  PNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

42) Y1U_C1648 in NC_017927


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score = 1159 bits (4395),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 685/880 (78%), Positives = 794/880 (91%), Gaps = 1/880 (0%)

Query  1    MTNQKKLLLIDGSSVAFRAFFALYNQIDRFRNNNGLHTNAIYGFHLMLDNLLERIQPTHV  60
            M N++KLLLIDGSSVAFRAFFALYNQIDRF+N++GLHTNAIYGFHLMLD+++ R++PTHV
Sbjct  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60

Query  61   LVAFDAGKTTFRTEMFADYKAGRAKTPEEFREQLPYIREMLAARGIAYYDLAQYEADDII  120
            LVAFDAGKTTFRTEM+ADYKAGRAKTP+EFREQ++YIREML+A GIAYY+L +YEADDII
Sbjct  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120

Query  121  GTLAKMAENTSEAFQITVVSGDKDLIQLTDENTVVEISKKGVAEFEAFTPDYLMEKMGIT  180
            GTL KMAE T  +F++T+VSGDKDLIQLTDENTVVEISKKGVAEFE FTP YLMEKMG+T
Sbjct  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180

Query  181  PAQFVDLKALMGDKSDNIPGVTKIGEKTGLKLLLEHGSLEGIYDHIDEMKKSKMKENLIN  240
            P QF+DLKALMGDKSDNIPGVTKIGEKTGLKLL E GSLEGIY+HID  K SKMKENLIN
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  241  DKEQAFLSKTLATIDTQSPIEIGLDDTAFKGPNLEKLLAFYDEMGFVHFKNALRREAVPQ  300
            D++QAFLSKTLATI+T SPI IGLDD  ++GP++  L  FYDEM+FV++K++L  +   +
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQE  300

Query  301  DFDV-AYVEPSQVTADHFSSEDFFYFEILGDNYHTEPIIGFAWGNEKQIYASTDTDLLKS  359
               V +Y E ++V+AD FS+ED+FYFE L DNYH E+IIGFAWG+  QIYASTD  LL +
Sbjct  301  PVAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLAT  360

Query  360  EAFQAALSKAVNIYDFKRSKVLLSHLGIDLPTANFDARLAKYLLSTVEDNELSTIARLYT  419
            ++F+  + K++  YDFKRSKVLLSHLGI+L ++++DARLA+YLLSTVEDNELSTIAR++T
Sbjct  361  DSFKQVFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIFT  420

Query  420  DLPLETDEVVYGKGAKRAIPEKEVLLSHlakkvkvlqvakpvMLEKLAEHGQSELLFDME  479
            D++LE D+ VYGKGAKRA+P+K+VLL HLA+KVKVL  +K+ ML+KL+ H Q +L  ++E
Sbjct  421  DISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNIE  480

Query  480  LPLANVLAKMEMAGIKVDGQTLNEMAVENQAVIDKLTQDIYEMAGEEFNINSPKQLGVIL  539
            LPLANVLAKME+ GIKV+  TL++MA +N+ +I+ LTQ+IY+MAG+EFNINSPKQLG IL
Sbjct  481  LPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSIL  540

Query  540  FEKMGLPLEYTKKTKTGYSTAVDVLERLAPIAPIVAKILEYRQITKLQSTYVLGLQDYIL  599
            FEKM LPLE TKKTKTGYSTAVDVLERLAPIAPIVAKIL+YRQITKLQSTYV+GLQDYIL
Sbjct  541  FEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYIL  600

Query  600  EDGKIHTRYMQDLTQTGRLSSVDPNLQNIPVRLEQGRLIRKAFVPSTKDAVLLSSDYSQI  659
             DGKIHTRY+QDLTQTGRLSSVDPNLQNIP+RLEQGRLIRKAF PS  DAVLLSSDYSQI
Sbjct  601  ADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQI  660

Query  660  ELRVLAHISGDEHLIAAFKEGADIHTSTAMRVFGIEKPEDVTPNDRRNAKAVNFGIVYGI  719
            ELRVLAHISGDEHLIAAF+EGADIHTSTAMRVFGI+K+ DVT+NDRRNAKAVNFGIVYGI
Sbjct  661  ELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGI  720

Query  720  SDFGLSNNLGISRKKAKEYIDTYFERYPGIKAYMDNVVREAKDKGYVSTLFHRRRELPDI  779
            SDFGLSNNLGI+RK++K YIDTYFERYPGIKAYM+NVVREAKDKGYV TLF RRRELPDI
Sbjct  721  SDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDI  780

Query  780  NSRNFNVRNFAERTAINSPIQGSAADILKIAMINLDKALVEGGYKTKMLLQVHDEIVLEV  839
            NSRNFNVR+FAERTAINSPIQGSAADILKIAMINLDKAL  GG+++KMLLQVHDEIVLEV
Sbjct  781  NSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEV  840

Query  840  PSDELLAMKALVKETMESAVELAVPLIADENEGCTWYEAK  879
            P+DEL A+K LVK+TME+AV+LAVPL  DE+ G +WYEAK
Sbjct  841  PNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

43) polA in NC_006449


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score = 1158 bits (4393),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 684/880 (78%), Positives = 794/880 (91%), Gaps = 1/880 (0%)

Query  1    MTNQKKLLLIDGSSVAFRAFFALYNQIDRFRNNNGLHTNAIYGFHLMLDNLLERIQPTHV  60
            M N++KLLLIDGSSVAFRAFFALYNQIDRF+N++GLHTNAIYGFHLMLD+++ R++PTHV
Sbjct  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60

Query  61   LVAFDAGKTTFRTEMFADYKAGRAKTPEEFREQLPYIREMLAARGIAYYDLAQYEADDII  120
            LVAFDAGKTTFRTEM+ADYKAGRAKTP+EFREQ++YIREML+A GIAYY+L +YEADDII
Sbjct  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120

Query  121  GTLAKMAENTSEAFQITVVSGDKDLIQLTDENTVVEISKKGVAEFEAFTPDYLMEKMGIT  180
            GTL KMAE T  +F++T+VSGDKDLIQLTDENTVVEISKKGVAEFE FTP YLMEKMG+T
Sbjct  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180

Query  181  PAQFVDLKALMGDKSDNIPGVTKIGEKTGLKLLLEHGSLEGIYDHIDEMKKSKMKENLIN  240
            P QF+DLKALMGDKSDNIPGVTKIGEKTGLKLL E GSLEGIY+HID  K SKMKENLIN
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  241  DKEQAFLSKTLATIDTQSPIEIGLDDTAFKGPNLEKLLAFYDEMGFVHFKNALRGEAVPQ  300
            D++QAFLSKTLATI+T SPI IGLDD  ++GP++  L  FYDEM+FV++K++L ++   +
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQE  300

Query  301  DFDV-AYVEPSQVTADHFSSEDFFYFEILGDNYHTEPIIGFAWGNEKQIYASTDTDLLKS  359
               V +Y E ++V+AD FS+ED+FYFE L DNYH E+IIGFAWG+  QIYASTD  LL +
Sbjct  301  PVAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLAT  360

Query  360  EAFQAALSKAVNIYDFKRSKVLLSHLGIDLPTANFDARLAKYLLSTVEDNELSTIARLYT  419
            ++F+  + K++  YDFKRSKVLLSHLGI+L ++++DARLA+YLLSTVEDNELSTIAR++T
Sbjct  361  DSFKQVFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIFT  420

Query  420  DLPLETDEVVYGKGAKRAIPEKEVLLSHlakkvkvlqvakpvMLEKLAEHGQSELLFDME  479
            D++LE D+ VYGKGAKRA+P+K+VLL HLA+KVKVL  +K+ ML+KL+ H Q +L  ++E
Sbjct  421  DISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNIE  480

Query  480  LPLANVLAKMEMAGIKVDGQTLNEMAVENQAVIDKLTQDIYEMAGEEFNINSPKQLGVIL  539
            LPLANVLAKME+ GIKV+  TL++MA +N+ +I+ LTQ+IY+MAG+EFNINSPKQLG IL
Sbjct  481  LPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSIL  540

Query  540  FEKMGLPLEYTKKTKTGYSTAVDVLERLAPIAPIVAKILEYRQITKLQSTYVLGLQDYIL  599
            FEKM LPLE TKKTKTGYSTAVDVLERLAPIAPIVAKIL+YRQITKLQSTYV+GLQDYIL
Sbjct  541  FEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYIL  600

Query  600  EDGKIHTRYMQDLTQTGRLSSVDPNLQNIPVRLEQGRLIRKAFVPSTKDAVLLSSDYSQI  659
             DGKIHTRY+QDLTQTGRLSSVDPNLQNIP+RLEQGRLIRKAF PS  DAVLLSSDYSQI
Sbjct  601  ADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQI  660

Query  660  ELRVLAHISGDEHLIAAFKEGADIHTSTAMRVFGIEKPEDVTPNDRRNAKAVNFGIVYGI  719
            ELRVLAHISGDEHLIAAF+EGADIHTSTAMRVFGI+K+ DVT+NDRRNAKAVNFGIVYGI
Sbjct  661  ELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGI  720

Query  720  SDFGLSNNLGISRKKAKEYIDTYFERYPGIKAYMDNVVREAKNKGYVSTLFHRRRELPDI  779
            SDFGLSNNLGI+RK++K YIDTYFERYPGIKAYM+NVVREAK+KGYV TLF RRRELPDI
Sbjct  721  SDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDI  780

Query  780  NSRNFNVRNFAERTAINSPIQGSAADILKIAMINLDKALVEGGYKTKMLLQVHDEIILEV  839
            NSRNFNVR+FAERTAINSPIQGSAADILKIAMINLDKAL  GG+++KMLLQVHDEI+LEV
Sbjct  781  NSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEV  840

Query  840  PRDELLAMKALVKETMEAAVELAVPLIADENEGCTWYEAK  879
            P DEL A+K LVK+TMEAAV+LAVPL  DE+ G +WYEAK
Sbjct  841  PNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

44) polA in NC_006448


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score = 1158 bits (4391),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 684/880 (78%), Positives = 793/880 (91%), Gaps = 1/880 (0%)

Query  1    MTNQKKLLLIDGSSVAFRAFFALYNQIDRFRNNNGLHTNAIYGFHLMLDNLLERIQPTHV  60
            M N++KLLLIDGSSVAFRAFFALYNQIDRF+N++GLHTNAIYGFHLMLD+++ R++PTHV
Sbjct  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60

Query  61   LVAFDAGKTTFRTEMFADYKAGRAKTPEEFREQLPYIREMLAARGIAYYDLAQYEADDII  120
            LVAFDAGKTTFRTEM+ADYKAGRAKTP+EFREQ++YIREML+A GIAYY+L +YEADDII
Sbjct  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120

Query  121  GTLAKMAENTSEAFQITVVSGDKDLIQLTDENTVVEISKKGVAEFEAFTPDYLMEKMGIT  180
            GTL KMAE T  +F++T+VSGDKDLIQLTDENTVVEISKKGVAEFE FTP YLMEKMG+T
Sbjct  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180

Query  181  PAQFVDLKALMGDKSDNIPGVTKIGEKTGLKLLLEHGSLEGIYDHIDEMKKSKMKENLIN  240
            P QF+DLKALMGDKSDNIPGVTKIGEKTGLKLL E GSLEGIY+HID  K SKMKENLIN
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  241  DKEQAFLSKTLATIDTQSPIEIGLDDTAFKGPNLEKLLAFYDEMGFVHFKNALRGEAVPQ  300
            D++QAFLSKTLATI+T SPI IGLDD  ++GP++  L  FYDEM+FV++K++L ++   +
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQE  300

Query  301  DFDV-AYVEPSQVTADHFSSEDFFYFEILGDNYHTEPIIGFAWGNEKQIYASTDTDLLKS  359
               V +Y E ++V+AD FS+ED+FYFE L DNYH E+IIGFAWG+  QIYASTD  LL +
Sbjct  301  PVAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLAT  360

Query  360  EAFQAALSKAVNIYDFKRSKVLLSHLGIDLPTANFDARLAKYLLSTVEDNELSTIARLYT  419
            ++F+  + K++  YDFKRSKVLLSHLGI+L ++++DARLA+YLLSTVEDNELSTIAR++T
Sbjct  361  DSFKQVFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIFT  420

Query  420  DLPLETDEVVYGKGAKRAIPEKEVLLSHlakkvkvlqvakpvMLEKLAEHGQSELLFDME  479
            D++LE D+ VYGKGAKRA+P+K+VLL HLA+KVKVL  +K+ ML+KL+ H Q +L  ++E
Sbjct  421  DISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNIE  480

Query  480  LPLANVLAKMEMAGIKVDGQTLNEMAVENQAVIDKLTQDIYEMAGEEFNINSPKQLGVIL  539
            LPLANVLAKME+ GIKV+  TL++MA +N+ +I+ LTQ+IY+MAG+EFNINSPKQLG IL
Sbjct  481  LPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSIL  540

Query  540  FEKMGLPLEYTKKTKTGYSTAVDVLERLAPIAPIVAKILEYRQITKLQSTYVLGLQDYIL  599
            FEKM LPLE TKKTKTGYSTAVDVLERLAPIAPIVAKIL+YRQITKLQSTYV+GLQDYIL
Sbjct  541  FEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYIL  600

Query  600  EDGKIHTRYMQDLTQTGRLSSVDPNLQNIPVRLEQGRLIRKAFVPSTKDAVLLSSDYSQI  659
             DGKIHTRY+QDLTQTGRLSSVDPNLQNIP+RLEQGRLIRKAF PS  DAVLLSSDYSQI
Sbjct  601  ADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQI  660

Query  660  ELRVLAHISGDEHLIAAFKEGADIHTSTAMRVFGIEKPEDVTPNDRRNAKAVNFGIVYGI  719
            ELRVLAHISGDEHLIAAF+EGADIHTSTAMRVFGI+K+ DVT+NDRRNAKAVNFGIVYGI
Sbjct  661  ELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGI  720

Query  720  SDFGLSNNLGISRKKAKEYIDTYFERYPGIKAYMDNVVREAKDKGYVSTLFHRRRELPDI  779
            SDFGLSNNLGI+RK++K YIDTYFERYPGIKAYM+NVVREAKDKGYV TLF RRRELPDI
Sbjct  721  SDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDI  780

Query  780  NSRNFNVRNFAERTAINSPIQGSAADILKIAMINLDKALVEGGYKTKMLLQVHDEIILEV  839
            NSRNFNVR+FAERTAINSPIQGSAADILKIAMINLDKAL  GG+++KMLLQVHDEI+LEV
Sbjct  781  NSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEV  840

Query  840  PRDELLAMKALVKETMEDAVELAVPLIADENEGCTWYEAK  879
            P DEL A+K LVK+TME AV+LAVPL  DE+ G +WYEAK
Sbjct  841  PNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

45) BSA_4690 in NC_021485


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score = 1157 bits (4386),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 666/881 (76%), Positives = 794/881 (91%), Gaps = 2/881 (0%)

Query  1    MTNKNKLLLIDGSSVAFRAFFALYNQIDRFKNNSGLHTNAIYGFHLMLNHILGRVQPSHI  60
            M NKNKLLLIDGSSVAFRAFFALYNQIDRFKN+SGLHTNAIYGFHLML+H++ RV+P+H+
Sbjct  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60

Query  61   LVAFDAGKTTFRTEMYADYKGGRAKTPDEFREQFPYIRQQLDVLGIKHYELEHYEADDII  120
            LVAFDAGKTTFRTEMYADYK+GRAKTPDEFREQF+YIR+ L  LGI  YELEHYEADDII
Sbjct  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120

Query  121  GTLAKQAEASNEHFDITVVSGDKDLIQLTDTNTVVEISKKGVAEFEEFTPAYLMEKMGIT  180
            GTL K AE ++  FD+T+VSGDKDLIQLTD NTVVEISKKGVAEFEEFTPAYLMEKMG+T
Sbjct  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180

Query  181  PSQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLSEYGSLEGIYENIEAMKQSKMKENLIN  240
            P+QFIDLKALMGDKSDNIPGVTKIGEKTGLKLL E+GSLEGIYE+I++ K SKMKENLIN
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  241  DKEQAFLSKTLATINIASPITIGLEDILYSGPQDIKALSQFYDEMDFKQFKAALGEETSQ  300
            D++QAFLSKTLATIN ASPITIGL+DI+Y+GP D+ +LSQFYDEMDF Q+K +L+ + +Q
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGP-DVASLSQFYDEMDFVQLKKGLASQMPQ  299

Query  301  EDFEV-DFTEVEQLKTEMFSDNDFYYFEMLGDNYHVEDLIGIAWGNSDTIYATSNVSLLQ  359
            E   V  + EV ++ +++FS +D++YFE L DNYH E +IG+AWG+++ IYA++++SLL 
Sbjct  300  EPVAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLA  359

Query  360  EALFKKALSKPIKTYDFKRSKVLLNRFNIDLPEPAFDTRLAKYLLSTTEDNLVSTIARLY  419
               FK+ + KPI TYDFKRSKVLL+++ I+L  P++D+RLA+YLLST EDN +STIAR++
Sbjct  360  TDSFKQVFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIF  419

Query  420  TNLPLDTDDAVYGKGAKRAIPEKTRFLEHLAKKVKVLVDSEANIMQQLKANEQEELLFEM  479
            T+++L+ DD+VYGKGAKRA+P+K  +LEHLA+KVKVL+DS ++++++L A+EQ +L  ++
Sbjct  420  TDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNI  479

Query  480  EQPLANVLAKMEIRGIKVKKNTLNEMAIENQKVIETLTQEIYELAGQEFNINSPKQLGKL  539
            E PLANVLAKMEI GIKV++ TL++MA +N+ +IE+LTQEIY++AGQEFNINSPKQLG +
Sbjct  480  ELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSI  539

Query  540  LFETLGLPVEMTKKTKTGYSTAVDVLERLAPISPLVTKILEYRQITKLQSTYIIGLQDYI  599
            LFE + LP+EMTKKTKTGYSTAVDVLERLAPI+P+V+KIL+YRQITKLQSTY+IGLQDYI
Sbjct  540  LFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYI  599

Query  600  LEDGKIHTRYVQDLTQTGRLSSSDPNLQNIPVRLEQGRLIRKAFVPSEDNAVLLSSDYSQ  659
            L DGKIHTRYVQDLTQTGRLSS DPNLQNIP+RLEQGRLIRKAF PS+++AVLLSSDYSQ
Sbjct  600  LADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQ  659

Query  660  IELRVLAHISKDEHLIAAFKEGADIHTSTAMRVFGIEKPENVTPNDRRNAKAVNFGIVYG  719
            IELRVLAHIS DEHLIAAF+EGADIHTSTAMRVFGI+K+ +VT+NDRRNAKAVNFGIVYG
Sbjct  660  IELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYG  719

Query  720  ISDFGLSHNLGIPRKLAKQYIDTYFERYPGIKNYMETVVREAKDKGYVETLFHRRRSLPD  779
            ISDFGLS+NLGI RK +K YIDTYFERYPGIK YME VVREAKDKGYVETLF RRR LPD
Sbjct  720  ISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPD  779

Query  780  INSRNFNIRQFAERTAINSPIQGSAADILKIAMINLDRVLDKGGYKSKMLLQVHDEIVLE  839
            INSRNFN+R FAERTAINSPIQGSAADILKIAMINLD+ L+ GG+++KMLLQVHDEIVLE
Sbjct  780  INSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLE  839

Query  840  VPNEEIGAIRELVTKTMESAISLSVPLIADENAGETWYEAK  880
            VPN+E+ AI+ LV  TME+A+ L+VPL  DE++G++WYEAK
Sbjct  840  VPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

46) polA in NC_004116


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score = 1157 bits (4386),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 666/881 (76%), Positives = 794/881 (91%), Gaps = 2/881 (0%)

Query  1    MTNKNKLLLIDGSSVAFRAFFALYNQIDRFKNNSGLHTNAIYGFHLMLNHILGRVQPSHI  60
            M NKNKLLLIDGSSVAFRAFFALYNQIDRFKN+SGLHTNAIYGFHLML+H++ RV+P+H+
Sbjct  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60

Query  61   LVAFDAGKTTFRTEMYADYKGGRAKTPDEFREQFPYIRQQLDVLGIKHYELEHYEADDII  120
            LVAFDAGKTTFRTEMYADYK+GRAKTPDEFREQF+YIR+ L  LGI  YELEHYEADDII
Sbjct  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120

Query  121  GTLAKQAEASNEHFDITVVSGDKDLIQLTDTNTVVEISKKGVAEFEEFTPAYLMEKMGIT  180
            GTL K AE ++  FD+T+VSGDKDLIQLTD NTVVEISKKGVAEFEEFTPAYLMEKMG+T
Sbjct  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180

Query  181  PSQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLSEYGSLEGIYENIEAMKQSKMKENLIN  240
            P+QFIDLKALMGDKSDNIPGVTKIGEKTGLKLL E+GSLEGIYE+I++ K SKMKENLIN
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  241  DKEQAFLSKTLATINIASPITIGLEDILYSGPQDIKALSQFYDEMDFKQFKAALGEETSQ  300
            D++QAFLSKTLATIN ASPITIGL+DI+Y+GP D+ +LSQFYDEMDF Q+K +L+ + +Q
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGP-DVASLSQFYDEMDFVQLKKGLASQMPQ  299

Query  301  EDFEV-DFTEVEQLKTEMFSDNDFYYFEMLGDNYHVEDLIGIAWGNSDTIYATSNVSLLQ  359
            E   V  + EV ++ +++FS +D++YFE L DNYH E +IG+AWG+++ IYA++++SLL 
Sbjct  300  EPVAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLA  359

Query  360  EALFKKALSKPIKTYDFKRSKVLLNRFNIDLPEPAFDTRLAKYLLSTTEDNLVSTIARLY  419
               FK+ + KPI TYDFKRSKVLL+++ I+L  P++D+RLA+YLLST EDN +STIAR++
Sbjct  360  TDSFKQVFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIF  419

Query  420  TNLPLDTDDAVYGKGAKRAIPEKTRFLEHLAKKVKVLVDSEANIMQQLKANEQEELLFEM  479
            T+++L+ DD+VYGKGAKRA+P+K  +LEHLA+KVKVL+DS ++++++L A+EQ +L  ++
Sbjct  420  TDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNI  479

Query  480  EQPLANVLAKMEIRGIKVKKNTLNEMAIENQKVIETLTQEIYELAGQEFNINSPKQLGKL  539
            E PLANVLAKMEI GIKV++ TL++MA +N+ +IE+LTQEIY++AGQEFNINSPKQLG +
Sbjct  480  ELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSI  539

Query  540  LFETLGLPVEMTKKTKTGYSTAVDVLERLAPISPLVTKILEYRQITKLQSTYIIGLQDYI  599
            LFE + LP+EMTKKTKTGYSTAVDVLERLAPI+P+V+KIL+YRQITKLQSTY+IGLQDYI
Sbjct  540  LFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYI  599

Query  600  LEDGKIHTRYVQDLTQTGRLSSSDPNLQNIPVRLEQGRLIRKAFVPSEDNAVLLSSDYSQ  659
            L DGKIHTRYVQDLTQTGRLSS DPNLQNIP+RLEQGRLIRKAF PS+++AVLLSSDYSQ
Sbjct  600  LADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQ  659

Query  660  IELRVLAHISKDEHLIAAFKEGADIHTSTAMRVFGIEKPENVTPNDRRNAKAVNFGIVYG  719
            IELRVLAHIS DEHLIAAF+EGADIHTSTAMRVFGI+K+ +VT+NDRRNAKAVNFGIVYG
Sbjct  660  IELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYG  719

Query  720  ISDFGLSHNLGIPRKLAKQYIDTYFERYPGIKNYMETVVREAKDKGYVETLFHRRRSLPD  779
            ISDFGLS+NLGI RK +K YIDTYFERYPGIK YME VVREAKDKGYVETLF RRR LPD
Sbjct  720  ISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPD  779

Query  780  INSRNFNIRQFAERTAINSPIQGSAADILKIAMINLDRVLDKGGYKSKMLLQVHDEIVLE  839
            INSRNFN+R FAERTAINSPIQGSAADILKIAMINLD+ L+ GG+++KMLLQVHDEIVLE
Sbjct  780  INSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLE  839

Query  840  VPNEEIGAIRELVTKTMESAISLSVPLIADENAGETWYEAK  880
            VPN+E+ AI+ LV  TME+A+ L+VPL  DE++G++WYEAK
Sbjct  840  VPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

47) polA in NC_007432


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score = 1157 bits (4386),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 666/881 (76%), Positives = 794/881 (91%), Gaps = 2/881 (0%)

Query  1    MTNKNKLLLIDGSSVAFRAFFALYNQIDRFKNNSGLHTNAIYGFHLMLNHILGRVQPSHI  60
            M NKNKLLLIDGSSVAFRAFFALYNQIDRFKN+SGLHTNAIYGFHLML+H++ RV+P+H+
Sbjct  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60

Query  61   LVAFDAGKTTFRTEMYADYKGGRAKTPDEFREQFPYIRQQLDVLGIKHYELEHYEADDII  120
            LVAFDAGKTTFRTEMYADYK+GRAKTPDEFREQF+YIR+ L  LGI  YELEHYEADDII
Sbjct  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120

Query  121  GTLAKQAEASNEHFDITVVSGDKDLIQLTDTNTVVEISKKGVAEFEEFTPAYLMEKMGIT  180
            GTL K AE ++  FD+T+VSGDKDLIQLTD NTVVEISKKGVAEFEEFTPAYLMEKMG+T
Sbjct  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180

Query  181  PSQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLSEYGSLEGIYENIEAMKQSKMKENLIN  240
            P+QFIDLKALMGDKSDNIPGVTKIGEKTGLKLL E+GSLEGIYE+I++ K SKMKENLIN
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  241  DKEQAFLSKTLATINIASPITIGLEDILYSGPQDIKALSQFYDEMDFKQFKAALGEETSQ  300
            D++QAFLSKTLATIN ASPITIGL+DI+Y+GP D+ +LSQFYDEMDF Q+K +L+ + +Q
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGP-DVASLSQFYDEMDFVQLKKGLASQMPQ  299

Query  301  EDFEV-DFTEVEQLKTEMFSDNDFYYFEMLGDNYHVEDLIGIAWGNSDTIYATSNVSLLQ  359
            E   V  + EV ++ +++FS +D++YFE L DNYH E +IG+AWG+++ IYA++++SLL 
Sbjct  300  EPVAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLA  359

Query  360  EALFKKALSKPIKTYDFKRSKVLLNRFNIDLPEPAFDTRLAKYLLSTTEDNLVSTIARLY  419
               FK+ + KPI TYDFKRSKVLL+++ I+L  P++D+RLA+YLLST EDN +STIAR++
Sbjct  360  TDSFKQVFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIF  419

Query  420  TNLPLDTDDAVYGKGAKRAIPEKTRFLEHLAKKVKVLVDSEANIMQQLKANEQEELLFEM  479
            T+++L+ DD+VYGKGAKRA+P+K  +LEHLA+KVKVL+DS ++++++L A+EQ +L  ++
Sbjct  420  TDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNI  479

Query  480  EQPLANVLAKMEIRGIKVKKNTLNEMAIENQKVIETLTQEIYELAGQEFNINSPKQLGKL  539
            E PLANVLAKMEI GIKV++ TL++MA +N+ +IE+LTQEIY++AGQEFNINSPKQLG +
Sbjct  480  ELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSI  539

Query  540  LFETLGLPVEMTKKTKTGYSTAVDVLERLAPISPLVTKILEYRQITKLQSTYIIGLQDYI  599
            LFE + LP+EMTKKTKTGYSTAVDVLERLAPI+P+V+KIL+YRQITKLQSTY+IGLQDYI
Sbjct  540  LFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYI  599

Query  600  LEDGKIHTRYVQDLTQTGRLSSSDPNLQNIPVRLEQGRLIRKAFVPSEDNAVLLSSDYSQ  659
            L DGKIHTRYVQDLTQTGRLSS DPNLQNIP+RLEQGRLIRKAF PS+++AVLLSSDYSQ
Sbjct  600  LADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQ  659

Query  660  IELRVLAHISKDEHLIAAFKEGADIHTSTAMRVFGIEKPENVTPNDRRNAKAVNFGIVYG  719
            IELRVLAHIS DEHLIAAF+EGADIHTSTAMRVFGI+K+ +VT+NDRRNAKAVNFGIVYG
Sbjct  660  IELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYG  719

Query  720  ISDFGLSHNLGIPRKLAKQYIDTYFERYPGIKNYMETVVREAKDKGYVETLFHRRRSLPD  779
            ISDFGLS+NLGI RK +K YIDTYFERYPGIK YME VVREAKDKGYVETLF RRR LPD
Sbjct  720  ISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPD  779

Query  780  INSRNFNIRQFAERTAINSPIQGSAADILKIAMINLDRVLDKGGYKSKMLLQVHDEIVLE  839
            INSRNFN+R FAERTAINSPIQGSAADILKIAMINLD+ L+ GG+++KMLLQVHDEIVLE
Sbjct  780  INSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLE  839

Query  840  VPNEEIGAIRELVTKTMESAISLSVPLIADENAGETWYEAK  880
            VPN+E+ AI+ LV  TME+A+ L+VPL  DE++G++WYEAK
Sbjct  840  VPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

48) polA in NC_018646


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score = 1157 bits (4386),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 666/881 (76%), Positives = 794/881 (91%), Gaps = 2/881 (0%)

Query  1    MTNKNKLLLIDGSSVAFRAFFALYNQIDRFKNNSGLHTNAIYGFHLMLNHILGRVQPSHI  60
            M NKNKLLLIDGSSVAFRAFFALYNQIDRFKN+SGLHTNAIYGFHLML+H++ RV+P+H+
Sbjct  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60

Query  61   LVAFDAGKTTFRTEMYADYKGGRAKTPDEFREQFPYIRQQLDVLGIKHYELEHYEADDII  120
            LVAFDAGKTTFRTEMYADYK+GRAKTPDEFREQF+YIR+ L  LGI  YELEHYEADDII
Sbjct  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120

Query  121  GTLAKQAEASNEHFDITVVSGDKDLIQLTDTNTVVEISKKGVAEFEEFTPAYLMEKMGIT  180
            GTL K AE ++  FD+T+VSGDKDLIQLTD NTVVEISKKGVAEFEEFTPAYLMEKMG+T
Sbjct  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180

Query  181  PSQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLSEYGSLEGIYENIEAMKQSKMKENLIN  240
            P+QFIDLKALMGDKSDNIPGVTKIGEKTGLKLL E+GSLEGIYE+I++ K SKMKENLIN
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  241  DKEQAFLSKTLATINIASPITIGLEDILYSGPQDIKALSQFYDEMDFKQFKAALGEETSQ  300
            D++QAFLSKTLATIN ASPITIGL+DI+Y+GP D+ +LSQFYDEMDF Q+K +L+ + +Q
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGP-DVASLSQFYDEMDFVQLKKGLASQMPQ  299

Query  301  EDFEV-DFTEVEQLKTEMFSDNDFYYFEMLGDNYHVEDLIGIAWGNSDTIYATSNVSLLQ  359
            E   V  + EV ++ +++FS +D++YFE L DNYH E +IG+AWG+++ IYA++++SLL 
Sbjct  300  EPVAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLA  359

Query  360  EALFKKALSKPIKTYDFKRSKVLLNRFNIDLPEPAFDTRLAKYLLSTTEDNLVSTIARLY  419
               FK+ + KPI TYDFKRSKVLL+++ I+L  P++D+RLA+YLLST EDN +STIAR++
Sbjct  360  TDSFKQVFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIF  419

Query  420  TNLPLDTDDAVYGKGAKRAIPEKTRFLEHLAKKVKVLVDSEANIMQQLKANEQEELLFEM  479
            T+++L+ DD+VYGKGAKRA+P+K  +LEHLA+KVKVL+DS ++++++L A+EQ +L  ++
Sbjct  420  TDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNI  479

Query  480  EQPLANVLAKMEIRGIKVKKNTLNEMAIENQKVIETLTQEIYELAGQEFNINSPKQLGKL  539
            E PLANVLAKMEI GIKV++ TL++MA +N+ +IE+LTQEIY++AGQEFNINSPKQLG +
Sbjct  480  ELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSI  539

Query  540  LFETLGLPVEMTKKTKTGYSTAVDVLERLAPISPLVTKILEYRQITKLQSTYIIGLQDYI  599
            LFE + LP+EMTKKTKTGYSTAVDVLERLAPI+P+V+KIL+YRQITKLQSTY+IGLQDYI
Sbjct  540  LFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYI  599

Query  600  LEDGKIHTRYVQDLTQTGRLSSSDPNLQNIPVRLEQGRLIRKAFVPSEDNAVLLSSDYSQ  659
            L DGKIHTRYVQDLTQTGRLSS DPNLQNIP+RLEQGRLIRKAF PS+++AVLLSSDYSQ
Sbjct  600  LADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQ  659

Query  660  IELRVLAHISKDEHLIAAFKEGADIHTSTAMRVFGIEKPENVTPNDRRNAKAVNFGIVYG  719
            IELRVLAHIS DEHLIAAF+EGADIHTSTAMRVFGI+K+ +VT+NDRRNAKAVNFGIVYG
Sbjct  660  IELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYG  719

Query  720  ISDFGLSHNLGIPRKLAKQYIDTYFERYPGIKNYMETVVREAKDKGYVETLFHRRRSLPD  779
            ISDFGLS+NLGI RK +K YIDTYFERYPGIK YME VVREAKDKGYVETLF RRR LPD
Sbjct  720  ISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPD  779

Query  780  INSRNFNIRQFAERTAINSPIQGSAADILKIAMINLDRVLDKGGYKSKMLLQVHDEIVLE  839
            INSRNFN+R FAERTAINSPIQGSAADILKIAMINLD+ L+ GG+++KMLLQVHDEIVLE
Sbjct  780  INSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLE  839

Query  840  VPNEEIGAIRELVTKTMESAISLSVPLIADENAGETWYEAK  880
            VPN+E+ AI+ LV  TME+A+ L+VPL  DE++G++WYEAK
Sbjct  840  VPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

49) polA in NC_004368


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score = 1157 bits (4386),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 666/881 (76%), Positives = 794/881 (91%), Gaps = 2/881 (0%)

Query  1    MTNKNKLLLIDGSSVAFRAFFALYNQIDRFKNNSGLHTNAIYGFHLMLNHILGRVQPSHI  60
            M NKNKLLLIDGSSVAFRAFFALYNQIDRFKN+SGLHTNAIYGFHLML+H++ RV+P+H+
Sbjct  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60

Query  61   LVAFDAGKTTFRTEMYADYKGGRAKTPDEFREQFPYIRQQLDVLGIKHYELEHYEADDII  120
            LVAFDAGKTTFRTEMYADYK+GRAKTPDEFREQF+YIR+ L  LGI  YELEHYEADDII
Sbjct  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120

Query  121  GTLAKQAEASNEHFDITVVSGDKDLIQLTDTNTVVEISKKGVAEFEEFTPAYLMEKMGIT  180
            GTL K AE ++  FD+T+VSGDKDLIQLTD NTVVEISKKGVAEFEEFTPAYLMEKMG+T
Sbjct  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180

Query  181  PSQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLSEYGSLEGIYENIEAMKQSKMKENLIN  240
            P+QFIDLKALMGDKSDNIPGVTKIGEKTGLKLL E+GSLEGIYE+I++ K SKMKENLIN
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  241  DKEQAFLSKTLATINIASPITIGLEDILYSGPQDIKALSQFYDEMDFKQFKAALGEETSQ  300
            D++QAFLSKTLATIN ASPITIGL+DI+Y+GP D+ +LSQFYDEMDF Q+K +L+ + +Q
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGP-DVASLSQFYDEMDFVQLKKGLASQMPQ  299

Query  301  EDFEV-DFTEVEQLKTEMFSDNDFYYFEMLGDNYHVEDLIGIAWGNSDTIYATSNVSLLQ  359
            E   V  + EV ++ +++FS +D++YFE L DNYH E +IG+AWG+++ IYA++++SLL 
Sbjct  300  EPVAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLA  359

Query  360  EALFKKALSKPIKTYDFKRSKVLLNRFNIDLPEPAFDTRLAKYLLSTTEDNLVSTIARLY  419
               FK+ + KPI TYDFKRSKVLL+++ I+L  P++D+RLA+YLLST EDN +STIAR++
Sbjct  360  TDSFKQVFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIF  419

Query  420  TNLPLDTDDAVYGKGAKRAIPEKTRFLEHLAKKVKVLVDSEANIMQQLKANEQEELLFEM  479
            T+++L+ DD+VYGKGAKRA+P+K  +LEHLA+KVKVL+DS ++++++L A+EQ +L  ++
Sbjct  420  TDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNI  479

Query  480  EQPLANVLAKMEIRGIKVKKNTLNEMAIENQKVIETLTQEIYELAGQEFNINSPKQLGKL  539
            E PLANVLAKMEI GIKV++ TL++MA +N+ +IE+LTQEIY++AGQEFNINSPKQLG +
Sbjct  480  ELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSI  539

Query  540  LFETLGLPVEMTKKTKTGYSTAVDVLERLAPISPLVTKILEYRQITKLQSTYIIGLQDYI  599
            LFE + LP+EMTKKTKTGYSTAVDVLERLAPI+P+V+KIL+YRQITKLQSTY+IGLQDYI
Sbjct  540  LFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYI  599

Query  600  LEDGKIHTRYVQDLTQTGRLSSSDPNLQNIPVRLEQGRLIRKAFVPSEDNAVLLSSDYSQ  659
            L DGKIHTRYVQDLTQTGRLSS DPNLQNIP+RLEQGRLIRKAF PS+++AVLLSSDYSQ
Sbjct  600  LADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQ  659

Query  660  IELRVLAHISKDEHLIAAFKEGADIHTSTAMRVFGIEKPENVTPNDRRNAKAVNFGIVYG  719
            IELRVLAHIS DEHLIAAF+EGADIHTSTAMRVFGI+K+ +VT+NDRRNAKAVNFGIVYG
Sbjct  660  IELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYG  719

Query  720  ISDFGLSHNLGIPRKLAKQYIDTYFERYPGIKNYMETVVREAKDKGYVETLFHRRRSLPD  779
            ISDFGLS+NLGI RK +K YIDTYFERYPGIK YME VVREAKDKGYVETLF RRR LPD
Sbjct  720  ISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPD  779

Query  780  INSRNFNIRQFAERTAINSPIQGSAADILKIAMINLDRVLDKGGYKSKMLLQVHDEIVLE  839
            INSRNFN+R FAERTAINSPIQGSAADILKIAMINLD+ L+ GG+++KMLLQVHDEIVLE
Sbjct  780  INSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLE  839

Query  840  VPNEEIGAIRELVTKTMESAISLSVPLIADENAGETWYEAK  880
            VPN+E+ AI+ LV  TME+A+ L+VPL  DE++G++WYEAK
Sbjct  840  VPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

50) MSA_4610 in NC_021486


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score = 1156 bits (4383),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 666/881 (76%), Positives = 793/881 (91%), Gaps = 2/881 (0%)

Query  1    MTNKNKLLLIDGSSVAFRAFFALYNQIDRFKNNSGLHTNAIYGFHLMLNHILGRVQPSHI  60
            M NKNKLLLIDGSSVAFRAFFALYNQIDRFKN+SGLHTNAIYGFHLML+H++ RV+P+H+
Sbjct  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60

Query  61   LVAFDAGKTTFRTEMYADYKGGRAKTPDEFREQFPYIRQQLDVLGIKHYELEHYEADDII  120
            LVAFDAGKTTFRTEMYADYK+GRAKTPDEFREQF+YIR+ L  LGI  YELEHYEADDII
Sbjct  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120

Query  121  GTLAKQAEASNEHFDITVVSGDKDLIQLTDTNTVVEISKKGVAEFEEFTPAYLMEKMGIT  180
            GTL K AE ++  FD+T+VSGDKDLIQLTD NTVVEISKKGVAEFEEFTPAYLMEKMG+T
Sbjct  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180

Query  181  PSQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLSEYGSLEGIYENIEAMKQSKMKENLIN  240
            P+QFIDLKALMGDKSDNIPGVTKIGEKTGLKLL E+GSLEGIYE+I++ K SKMKENLIN
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  241  DKEQAFLSKTLATINIASPITIGLEDILYSGPQDIKALSQFYDEMDFKQFKAALGEETSQ  300
            D++QAFLSKTLATIN ASPITIGL+DI+Y+GP D+ +LSQFYDEMDF Q+K +L+ + +Q
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGP-DVASLSQFYDEMDFVQLKKGLASQMPQ  299

Query  301  EDFEV-DFTEVEQLKPEMFSDNDFYYFEMLGDNYHVEDLIGIAWGNSDTIYATSNVSLLQ  359
            E   V  + EV ++ +++FS +D++YFE L DNYH E +IG+AWG+++ IYA++++SLL 
Sbjct  300  EPVAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLA  359

Query  360  EALFKKALSKPIKTYDFKRSKVLLNRFNIDLPEPAFDTRLAKYLLSTTEDNLVSTIARLY  419
               FK+ + KPI TYDFKRSKVLL+++ I+L  P++D+RLA+YLLST EDN +STIAR++
Sbjct  360  TDSFKQVFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIF  419

Query  420  TNLPLDTDDAVYGKGAKRAIPEKTRFLEHLAKKVKVLVDSEANIMQQLKVNEQEELLFEM  479
            T+++L+ DD+VYGKGAKRA+P+K  +LEHLA+KVKVL+DS ++++++L  +EQ +L  ++
Sbjct  420  TDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNI  479

Query  480  EQPLANVLAKMEIRGIKVKKNTLNEMAIENQKVIETLTQEIYELAGQEFNINSPKQLGKL  539
            E PLANVLAKMEI GIKV++ TL++MA +N+ +IE+LTQEIY++AGQEFNINSPKQLG +
Sbjct  480  ELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSI  539

Query  540  LFETLGLPVEMTKKTKTGYSTAVDVLERLAPISPLVTKILEYRQITKLQSTYIIGLQDYI  599
            LFE + LP+EMTKKTKTGYSTAVDVLERLAPI+P+V+KIL+YRQITKLQSTY+IGLQDYI
Sbjct  540  LFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYI  599

Query  600  LEDGKIHTRYVQDLTQTGRLSSSDPNLQNIPVRLEQGRLIRKAFVPSEDNAVLLSSDYSQ  659
            L DGKIHTRYVQDLTQTGRLSS DPNLQNIP+RLEQGRLIRKAF PS+++AVLLSSDYSQ
Sbjct  600  LADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQ  659

Query  660  IELRVLAHISKDEHLIAAFKEGADIHTSTAMRVFGIEKPENVTPNDRRNAKAVNFGIVYG  719
            IELRVLAHIS DEHLIAAF+EGADIHTSTAMRVFGI+K+ +VT+NDRRNAKAVNFGIVYG
Sbjct  660  IELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYG  719

Query  720  ISDFGLSHNLGIPRKLAKQYIDTYFERYPGIKNYMETVVREAKDKGYVETLFHRRRSLPD  779
            ISDFGLS+NLGI RK +K YIDTYFERYPGIK YME VVREAKDKGYVETLF RRR LPD
Sbjct  720  ISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPD  779

Query  780  INSRNFNIRQFAERTAINSPIQGSAADILKIAMINLDRVLDKGGYKSKMLLQVHDEIVLE  839
            INSRNFN+R FAERTAINSPIQGSAADILKIAMINLD+ L+ GG+++KMLLQVHDEIVLE
Sbjct  780  INSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLE  839

Query  840  VPNEEIGAIKELVTKTMESAISLSVPLIADENAGETWYEAK  880
            VPN+E+ AIK LV  TME+A+ L+VPL  DE++G++WYEAK
Sbjct  840  VPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

51) SAIL_4710 in NC_021507


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score = 1156 bits (4384),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 667/881 (76%), Positives = 793/881 (91%), Gaps = 2/881 (0%)

Query  1    MTNKNKLLLIDGSSVAFRAFFALYNQIDRFKNNSGLHTNAIYGFHLMLNHILGRVQPSHI  60
            M NKNKLLLIDGSSVAFRAFFALYNQIDRFKN+SGLHTNAIYGFHLML+H++ RV+P+H+
Sbjct  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60

Query  61   LVAFDAGKTTFRTEMYADYKGGRAKTPDEFREQFPYIRQQLDVLGIKHYELEHYEADDII  120
            LVAFDAGKTTFRTEMYADYK+GRAKTPDEFREQF+YIR+ L  LGI  YELEHYEADDII
Sbjct  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120

Query  121  GTLAKQAEASNEHFDITVVSGDKDLIQLTDTNTVVEISKKGVAEFEEFTPAYLMEKMGIT  180
            GTL K AE ++  FD+T+VSGDKDLIQLTD NTVVEISKKGVAEFEEFTPAYLMEKMG+T
Sbjct  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180

Query  181  PSQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLSEYGSLEGIYENIEAMKQSKMKENLIN  240
            P+QFIDLKALMGDKSDNIPGVTKIGEKTGLKLL E+GSLEGIYE+I++ K SKMKENLIN
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  241  DKEQAFLSKTLATINIASPITIGLEDILYNGPQDIKALSQFYDEMDFKQFKAALGEETSQ  300
            D++QAFLSKTLATIN ASPITIGL+DI+YNGP D+ +LSQFYDEMDF Q+K +L+ + +Q
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGP-DVASLSQFYDEMDFVQLKKGLASQMPQ  299

Query  301  EDFEV-DFTEVEQLKPEMFSDNDFYYFEMLGDNYHVEDLIGIAWGNSDTIYATSNVSLLQ  359
            E   V  + EV ++ +++FS +D++YFE L DNYH E +IG+AWG+++ IYA++++SLL 
Sbjct  300  EPVAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLA  359

Query  360  EALFKKALSKPIKTYDFKRSKVLLNRFNIDLPEPAFDTRLAKYLLSTTEDNLVSTIARLY  419
               FK+ + KPI TYDFKRSKVLL+++ I+L  P++D+RLA+YLLST EDN +STIAR++
Sbjct  360  TDSFKQVFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIF  419

Query  420  TNLPLDTDDAVYGKGAKRAIPEKTRFLEHLAKKVKVLVDSEANIMQQLKVNEQEELLFEM  479
            T+++L+ DD+VYGKGAKRA+P+K  +LEHLA+KVKVL+DS ++++++L  +EQ +L  ++
Sbjct  420  TDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNI  479

Query  480  EQPLANVLAKMEIRGIKVKKNTLNEMAIENQKVIETLTQEIYELAGQEFNINSPKQLGKL  539
            E PLANVLAKMEI GIKV++ TL++MA +N+ +IE+LTQEIY++AGQEFNINSPKQLG +
Sbjct  480  ELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSI  539

Query  540  LFETLGLPVEMTKKTKTGYSTAVDVLERLAPISPLVTKILEYRQITKLQSTYIIGLQDYI  599
            LFE + LP+EMTKKTKTGYSTAVDVLERLAPI+P+V+KIL+YRQITKLQSTY+IGLQDYI
Sbjct  540  LFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYI  599

Query  600  LEDGKIHTRYVQDLTQTGRLSSSDPNLQNIPVRLEQGRLIRKAFIPSEDNAVLLSSDYSQ  659
            L DGKIHTRYVQDLTQTGRLSS DPNLQNIP+RLEQGRLIRKAF PS+++AVLLSSDYSQ
Sbjct  600  LADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQ  659

Query  660  IELRVLAHISKDEHLIAAFKEGADIHTSTAMRVFGIEKPENVTPNDRRNAKAVNFGIVYG  719
            IELRVLAHIS DEHLIAAF+EGADIHTSTAMRVFGI+K+ +VT+NDRRNAKAVNFGIVYG
Sbjct  660  IELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYG  719

Query  720  ISDFGLSHNLGIPRKLAKQYIDTYFERYPGIKNYMETVVREAKDKGYVETLFHRRRSLPD  779
            ISDFGLS+NLGI RK +K YIDTYFERYPGIK YME VVREAKDKGYVETLF RRR LPD
Sbjct  720  ISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPD  779

Query  780  INSRNFNIRQFAERTAINSPIQGSAADILKIAMINLDRVLDKGGYKSKMLLQVHDEIVLE  839
            INSRNFN+R FAERTAINSPIQGSAADILKIAMINLD+ L+ GG+++KMLLQVHDEIVLE
Sbjct  780  INSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLE  839

Query  840  VPNEEIGAIKELVTKTMESAISLSVPLIADENAGETWYEAK  880
            VPN+E+ AIK LV  TME+A+ L+VPL  DE++G++WYEAK
Sbjct  840  VPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

52) polA in NC_016749


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score = 1150 bits (4361),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 678/880 (78%), Positives = 780/880 (89%), Gaps = 2/880 (0%)

Query  1    MENKKKLLLIDGSSVAYRAFFALYNQIDRFKNRAGLHTNAIYGFHLMLNHLLERVQPTHV  60
            MENK+KLLLIDGSSVA+RAFFALYNQIDRFKN++GLHTNAIYGFHLML+H++ RV+PTHV
Sbjct  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60

Query  61   LVAFDAGKTTFRTEMYKDYKAGRAKTPDEFREQLPYIREMLSALGITFYDLENYEADDII  120
            LVAFDAGKTTFRTEMY DYKAGRAKTPDEFREQ++YIREML+ALGI++Y+LE+YEADDII
Sbjct  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120

Query  121  GTLDKLAENED-EYDVTIVSGDKDLIQLADNNTTVEISKKGVAEFEEFTPDYLMEKMGIT  179
            GTLDK+AE  +  +DVTIVSGDKDLIQL+D+NT VEISKKGVAEFEEFTP YLMEKMG+T
Sbjct  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180

Query  180  PKQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLLEYGSLEGVYESIDGMKKSKTKENLIN  239
            P+QFIDLKALMGDKSDNIPGVTKIGEKTGLKLL E+GSLEG+YE IDG K SK KENLIN
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  240  DKEQAFLSKTLATINISAPITIGLDDINYQGPDLDKLVPFYDEMDFKQFKDNLGAPKKQE  299
            D++QAFLSKTLATIN ++PITIGLDDI Y+GPD+  L  FYDEMDF Q+K  L++   QE
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQE  300

Query  300  KFDV-SYTEVDSLSADMFTDDQFFYFEILGDNYHVENIIGFAWGNDKVIYASTNlellkd  358
               V SY EV ++SAD+F+ +++FYFE L DNYH E IIGFAWG++  IYAST+L LL  
Sbjct  301  PVAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLAT  360

Query  359  dlfkaalakPIKTYDFKRSKVLLSHLSVDLPAPAFDSRLAKYLLSTVDDNELSTIARLYT  418
            D FK  + KPI TYDFKRSKVLLSHL+++L AP++D+RLA+YLLSTV+DNELSTIAR++T
Sbjct  361  DSFKQVFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIFT  420

Query  419  DYVLDSDEAVYGKGVKRAVPEKAVLLSHLARKIVVLNHSEKVMLDKLTEHQQASLLFDIE  478
            D  L+ D++VYGKG KRAVP+K VLL HLARK+ VL +S   MLDKLT H+Q  L  +IE
Sbjct  421  DISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNIE  480

Query  479  QPLANVLAKMEIAGISVKKTTLQEMEASNQAIIDELTQEIYDLAGMEFNINSPKQLSELL  538
             PLANVLAKMEI GI V+++TLQ+M   N+ II+ LTQEIYD+AG EFNINSPKQL+ +L
Sbjct  481  LPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSIL  540

Query  539  FDKMQLPTSYTKKTKIGYSTAVDVLERLAPISPIVSKILEYRQIAKLQSTYIVGLQDFIL  598
            F+KMQLP   TKKTK GYSTAVDVLERLAPI+PIV+KIL+YRQI+KLQSTY++GLQD+IL
Sbjct  541  FEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYIL  600

Query  599  QDGKIHTRYLQDLTQTGRLSSVDPNLQNIPVRLEQGRLIRKAFVPETEDEVLLSSDYSQI  658
             DGKIHTRY+QDLTQTGRLSSVDPNLQNIP+RLEQGRLIRKAF P  ED VLLSSDYSQI
Sbjct  601  ADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQI  660

Query  659  ELRVLAHISNDEHLIAAFREGADIHTSTAMRVFGIEKTEDVTPNDRRNAKAVNFGIVYGI  718
            ELRVLAHIS DEHLIAAF EGADIHTSTAMRVFGI+K+ DVT+NDRRNAKAVNFGIVYGI
Sbjct  661  ELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGI  720

Query  719  SDYGLANNLGIPRKVAKQYIETYFERYPGIKNYMERVVRDAKDKGYVETLFHRRRELPDI  778
            SD+GL+NNLGI RK +K YI+TYFERYPGIK YME VVR+AKDKGYVETLF RRRELPDI
Sbjct  721  SDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDI  780

Query  779  NSRNFNIRQFAERTAINSPIQGSAADILKIAMINLDKALVDGQFKTKMLLQVHDEIILQV  838
            NSRNFN+R FAERTAINSPIQGSAADILKIAMINLDKAL  G F++KMLLQVHDEI+L+V
Sbjct  781  NSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEV  840

Query  839  PKDELEAVKTLVKETMESAIDLSVPLIADENVGQTWYEAK  878
            P+DEL A+K LVK+TME+A+DL+VPL  DE+ GQ+WYEAK
Sbjct  841  PNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

53) polA in NC_021195


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score = 1149 bits (4357),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 663/881 (76%), Positives = 790/881 (90%), Gaps = 2/881 (0%)

Query  1    MTNKNKLLLIDGSSVAFRAFFALYNQIDRFKNNSGLHTNAIYGFHLMLNHILGRVQPSHI  60
            M NKNKLLLIDGSSVAFRAFFALYNQIDRFKN+SGLHTNAIYGFHLML+H++ RV+P+H+
Sbjct  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60

Query  61   LVAFDAGKTTFRTEMYADYKGGRAKTPDEFREQFPYIRQQLDVLGIKHYELEHYEADDII  120
            LVAFDAGKTTFRTEMYADYK+GRAKTPDEFREQF+YIR+ L  LGI  YELEHYEADDII
Sbjct  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120

Query  121  GTLAKQAEASKEHFDITVVSGDKDLIQLTDTNTVVEISKKGVAEFEEFTPAYLMEKMGIT  180
            GTL K AE +   FD+T+VSGDKDLIQLTD NTVVEISKKGVAEFEEFTPAYLMEKMG+T
Sbjct  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180

Query  181  PSQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLSEYGSLEGIYENIEAMKQSKMKENLIN  240
            P+QFIDLKALMGDKSDNIPGVTKIGEKTGLKLL E+GSLEGIYE+I++ K SKMKENLIN
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  241  DKEQAFLSKTLATINIASPITIGLEDVLYSGPQDIKALSQFYDEMDFKQFKAALGEETSQ  300
            D++QAFLSKTLATIN ASPITIGL+D++Y+GP D+ +LSQFYDEMDF Q+K +L+ + +Q
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGP-DVASLSQFYDEMDFVQLKKGLASQMPQ  299

Query  301  EDFEV-DFTEVEQLKPEMFSDNDFYYFEMLGDNYHVEDLIGIAWGNSDTIYATSNVSLLQ  359
            E   V  + EV ++ +++FS +D++YFE L DNYH E +IG+AWG+++ IYA++++SLL 
Sbjct  300  EPVAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLA  359

Query  360  EALFKKALSKPIKTYDFKRSKVLLNRFNIDLPEPAFDTRLAKYLLSTTEDNLVSTIARLY  419
               FK+ + KPI TYDFKRSKVLL+++ I+L  P++D+RLA+YLLST EDN +STIAR++
Sbjct  360  TDSFKQVFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIF  419

Query  420  TNLPLDTDDAVYGKGAKRAIPEKTRFLEHLAKKVKVLVDSEANIMQQLKANEQEELLFEM  479
            T+++L+ DD+VYGKGAKRA+P+K  +LEHLA+KVKVL+DS ++++++L A+EQ +L  ++
Sbjct  420  TDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNI  479

Query  480  EQPLANVLAKMEIRGIKVKKNTLNEMAIENQKVIETLTQEIYELAGQEFNINSPKQLGKL  539
            E PLANVLAKMEI GIKV++ TL++MA +N+ +IE+LTQEIY++AGQEFNINSPKQLG +
Sbjct  480  ELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSI  539

Query  540  LFETLGLPVEMTKKTKIGYSTAVDVLERLAPISPLVTKILEYRQITKLQSTYIIGLQDYI  599
            LFE + LP+EMTKKTK GYSTAVDVLERLAPI+P+V+KIL+YRQITKLQSTY+IGLQDYI
Sbjct  540  LFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYI  599

Query  600  LEDGKIHTRYVQDLTQTGRLSSSDPNLQNIPVRLEQGRLIRKAFVPSEDNAVLLSSDYSQ  659
            L DGKIHTRYVQDLTQTGRLSS DPNLQNIP+RLEQGRLIRKAF PS+++AVLLSSDYSQ
Sbjct  600  LADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQ  659

Query  660  IELRVLAHISKDKHLIAAFKEGADIHTSTAMRVFGIEKPENVTPNDRRNAKAVNFGIVYG  719
            IELRVLAHIS D HLIAAF+EGADIHTSTAMRVFGI+K+ +VT+NDRRNAKAVNFGIVYG
Sbjct  660  IELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYG  719

Query  720  ISDFGLSHNLGIPRKLAKQYIDTYFERYPGIKNYMETVVREAKDKGYVETLFHRRRSLPD  779
            ISDFGLS+NLGI RK +K YIDTYFERYPGIK YME VVREAKDKGYVETLF RRR LPD
Sbjct  720  ISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPD  779

Query  780  INSRNFNIRQFAERTAINSPIQGSAADILKIAMINLDRVLDKGGYKSKMLLQVHDEIVLE  839
            INSRNFN+R FAERTAINSPIQGSAADILKIAMINLD+ L+ GG+++KMLLQVHDEIVLE
Sbjct  780  INSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLE  839

Query  840  VLNEEIGAIKELVTKTMESAISLSVPLIADENAGETWYEAK  880
            V N+E+ AIK LV  TME+A+ L+VPL  DE++G++WYEAK
Sbjct  840  VPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

54) polA in NC_019048


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score = 1148 bits (4352),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 662/881 (76%), Positives = 790/881 (90%), Gaps = 2/881 (0%)

Query  1    MTNKNKLLFIDGSSVAFRAFFALYNQIDRFKNNSGLHTNAIYGFHLMLNHILGRVQPSHI  60
            M NKNKLL+IDGSSVAFRAFFALYNQIDRFKN+SGLHTNAIYGFHLML+H++ RV+P+H+
Sbjct  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60

Query  61   LVAFDAGKTTFRTEMYADYKGGRAKTPDEFREQFPYIRQQLDVLGIKHYELEHYEADDII  120
            LVAFDAGKTTFRTEMYADYK+GRAKTPDEFREQF+YIR+ L  LGI  YELEHYEADDII
Sbjct  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120

Query  121  GTLAKQAEASKEHFDITVVSGDKDLIQLTDTNTVVEISKKGVAEFEEFTPAYLMEKMGIT  180
            GTL K AE +   FD+T+VSGDKDLIQLTD NTVVEISKKGVAEFEEFTPAYLMEKMG+T
Sbjct  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180

Query  181  PSQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLSEYGSLEGIYENIEAMKQSKMKENLIN  240
            P+QFIDLKALMGDKSDNIPGVTKIGEKTGLKLL E+GSLEGIYE+I++ K SKMKENLIN
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  241  DKEQAFLSKTLATINIASPITIGLEDVLYSGPQDIKALSQFYDEMDFKQFKAALGEETSQ  300
            D++QAFLSKTLATIN ASPITIGL+D++Y+GP D+ +LSQFYDEMDF Q+K +L+ + +Q
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGP-DVASLSQFYDEMDFVQLKKGLASQMPQ  299

Query  301  EDFEV-DFTEVEQLKPEMFSDNDFYYFEMLGDNYHVEDLIGIAWGNSDTIYATSNVSLLQ  359
            E   V  + EV ++ +++FS +D++YFE L DNYH E +IG+AWG+++ IYA++++SLL 
Sbjct  300  EPVAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLA  359

Query  360  EALFKKALSKPIKTYDFKRSKVLLNRFNIDLPEPAFDTRLAKYLLSTTEDNLVSTIARLY  419
               FK+ + KPI TYDFKRSKVLL+++ I+L  P++D+RLA+YLLST EDN +STIAR++
Sbjct  360  TDSFKQVFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIF  419

Query  420  TNLPLDTDDAVYGKGAKRAIPEKTRFLEHLAKKVKVLVDSEANIMQQLKANEQEELLFEM  479
            T+++L+ DD+VYGKGAKRA+P+K  +LEHLA+KVKVL+DS ++++++L A+EQ +L  ++
Sbjct  420  TDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNI  479

Query  480  EQPLANVLAKMEIRGIKVKKNTLNEMAIENQKVIETLTQEIYELAGQEFNINSPKQLGKL  539
            E PLANVLAKMEI GIKV++ TL++MA +N+ +IE+LTQEIY++AGQEFNINSPKQLG +
Sbjct  480  ELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSI  539

Query  540  LFETLGLPVEMTKKTKIGYSTAVDVLERLAPISPLVTKILEYRQITKLQSTYIIGLQDYI  599
            LFE + LP+EMTKKTK GYSTAVDVLERLAPI+P+V+KIL+YRQITKLQSTY+IGLQDYI
Sbjct  540  LFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYI  599

Query  600  LEDGKIHTRYVQDLTQTGRLSSSDPNLQNIPVRLEQGRLIRKAFVPSEDNAVLLSSDYSQ  659
            L DGKIHTRYVQDLTQTGRLSS DPNLQNIP+RLEQGRLIRKAF PS+++AVLLSSDYSQ
Sbjct  600  LADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQ  659

Query  660  IELRVLAHISKDKHLIAAFKEGADIHTSTAMRVFGIEKPENVTPNDRRNAKAVNFGIVYG  719
            IELRVLAHIS D HLIAAF+EGADIHTSTAMRVFGI+K+ +VT+NDRRNAKAVNFGIVYG
Sbjct  660  IELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYG  719

Query  720  ISDFGLSHNLGIPRKLAKQYIDTYFERYPGIKNYMETVVREAKDKGYVETLFHRRRSLPD  779
            ISDFGLS+NLGI RK +K YIDTYFERYPGIK YME VVREAKDKGYVETLF RRR LPD
Sbjct  720  ISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPD  779

Query  780  INSRNFNIRQFAERTAINSPIQGSAADILKIAMINLDRVLDKGGYKSKMLLQVHDEIVLE  839
            INSRNFN+R FAERTAINSPIQGSAADILKIAMINLD+ L+ GG+++KMLLQVHDEIVLE
Sbjct  780  INSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLE  839

Query  840  VLNEEIGAIKELVTKTMESAISLSVPLIADENAGETWYEAK  880
            V N+E+ AIK LV  TME+A+ L+VPL  DE++G++WYEAK
Sbjct  840  VPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

55) polI in NC_009785


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score = 1147 bits (4348),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 671/883 (76%), Positives = 793/883 (90%), Gaps = 6/883 (0%)

Query  1    MEKKNKLLLIDGSSVAFRAFFALYNQIDRFKSPSGLHTNAIYGFHLMLNHLLERVQPTHV  60
            ME+KNKLLLIDGSSVAFRAFFALYNQIDRFK+ SGLHTNAIYGFHLML+H++ RV+PTHV
Sbjct  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60

Query  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQLPFIREMLQHLGIHYYDLAQYEADDII  120
            LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQ+++IREML  LGI YY+L +YEADDII
Sbjct  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120

Query  121  GTLDKMAEKTAVPYDVTIVSGDKDLIQLTDDNTVVEISKKGVAEFEEFTPAYLMEKMGIT  180
            GTLDKMAE+T VP+DVTIVSGDKDLIQLTD+NTVVEISKKGVAEFEEFTPAYLMEKMG+T
Sbjct  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180

Query  181  PEQFIDLKALMGDQSDNIPGVTKIGEKTGLKLLLEYGSLENLYENIDQLKASKMKENLIN  240
            P+QFIDLKALMGD+SDNIPGVTKIGEKTGLKLL E+GSLE +YE+ID +K+SKMKENLIN
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  241  DKDKAFLSKTLATINTQAPIEIGLDDLVYKGPQVEALSKFYDEMGFKQLKAQLGT--TQE  298
            D+D+AFLSKTLATINT +PI IGLDD+VY+GP+V +LS+FYDEM+F QLK  L++   QE
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQE  300

Query  299  PVEVKPIEFTKVTEVTADMLGPEQFFYFEILGDNYHREEIVGLAWGDSRQIYVGSS-DLL  357
            PV V  I +  VT+V+AD++++E++FYFE L DNYHRE I+G+AWG++ QIY ++   LL
Sbjct  301  PVAV--ISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLL  358

Query  358  QQPLFQEFLTKTALKTYDLKRAKVLLSHYGIELPAATFDARLAKYLLSTVEDNELATIAR  417
                F++ + K ++ TYD+KR+KVLLSH GIEL A+++DARLA+YLLSTVEDNEL+TIAR
Sbjct  359  ATDSFKQVFQK-PIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIAR  417

Query  418  LYGQTILPTDDEVYGKGAKRALPEQEQLFEHLARKVQVLLETEEPMQEQLRSHDQLDLLF  477
            ++ +  L  DD VYGKGAKRA+P+++ L+EHLARKV+VLL++   M ++L +H+QLDL  
Sbjct  418  IFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQ  477

Query  478  EMEQPLAFVLAKMEIAGIKVERETLQGMQAENEKTLESLTQEIYDLAGQEFNINSPKQLG  537
            ++E PLA VLAKMEI GIKV+R TLQ+M  +N   +E+LTQEIYD+AGQEFNINSPKQLG
Sbjct  478  NIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLG  537

Query  538  TILFEDMGLPLEYTKKTKTGYSTAVDVLERLAPIAPIVSKILEYRQISKLQSTYIIGLQE  597
            +ILFE M LPLE TKKTKTGYSTAVDVLERLAPIAPIV+KIL+YRQI+KLQSTY+IGLQ+
Sbjct  538  SILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQD  597

Query  598  AIAADGKIHTRYVQDLTQTGRLSSVDPNLQNIPVRLEQGRLIRKAFVPEWADSVLLSSDY  657
             I ADGKIHTRYVQDLTQTGRLSSVDPNLQNIP+RLEQGRLIRKAF P   D+VLLSSDY
Sbjct  598  YILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDY  657

Query  658  SQIELRVLAHISQDEHLIAAFQHGEDIHTATAMRVFGIEKAEDVTPNDRRNAKAVNFGVV  717
            SQIELRVLAHIS DEHLIAAF++G DIHT+TAMRVFGI+KA DVT+NDRRNAKAVNFG+V
Sbjct  658  SQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIV  717

Query  718  YGISDFGLANNLGISRKAAKDYIQTYFERFPGIKNYMETIVREARDKGYVETIYHRRRSL  777
            YGISDFGL+NNLGI+RK +K YI+TYFER+PGIK YME +VREA+DKGYVET++ RRR L
Sbjct  718  YGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRREL  777

Query  778  PDINSRNFNIRNFAERTAINSPIQGSAADILKVAMINLDRALTEKNFKSRMLLQVHDEIV  837
            PDINSRNFN+R+FAERTAINSPIQGSAADILK+AMINLD+AL    F+++MLLQVHDEIV
Sbjct  778  PDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIV  837

Query  838  LEVPNDELTAVRQLVKETMEAAIELAVPLVADENAGQTWYEAK  880
            LEVPNDELTA+++LVK+TMEAA++LAVPL  DE++GQ+WYEAK
Sbjct  838  LEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

56) I872_00430 in NC_021175


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score = 1146 bits (4346),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 674/883 (77%), Positives = 792/883 (90%), Gaps = 6/883 (0%)

Query  1    MEKKNKLLLIDGSSVAFRAFFALYNQIDRFKSPSGLHTNAIYGFHLMLNHLLERVQPTHV  60
            ME+KNKLLLIDGSSVAFRAFFALYNQIDRFK+ SGLHTNAIYGFHLML+H++ RV+PTHV
Sbjct  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60

Query  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQLPFIREMLDYLGIRYYDLAQYEADDII  120
            LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQ+++IREML  LGI YY+L +YEADDII
Sbjct  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120

Query  121  GTLDKMAEKTAVPYDVTIVSGDKDLIQLTDDNTVVEISKKGVAEFEEFTPAYLMEKMGIT  180
            GTLDKMAE+T VP+DVTIVSGDKDLIQLTD+NTVVEISKKGVAEFEEFTPAYLMEKMG+T
Sbjct  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180

Query  181  PEQFIDLKALMGDQSDNIPGVTKIGEKTGLKLLLEYGSLENLYENIDQLKASKMKENLIN  240
            P+QFIDLKALMGD+SDNIPGVTKIGEKTGLKLL E+GSLE +YE+ID +K+SKMKENLIN
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  241  DKDKAFLSKTLATINTQAPIEIGLDDLVYNGPQLEALSKFYDEMGFKQLKAQLGT--TQE  298
            D+D+AFLSKTLATINT +PI IGLDD+VYNGP++ +LS+FYDEM+F QLK  L++   QE
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQE  300

Query  299  PVEVKPIEFTKVTEVTADMLVPEQFFYFEILGDNYHKEEIVGLAWGDSRQIYVGTS-DLL  357
            PV V  I +  VT+V+AD++ +E++FYFE L DNYH+E I+G+AWG++ QIY +T   LL
Sbjct  301  PVAV--ISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLL  358

Query  358  QQPLFQEFLTKTALKTYDLKRTKVLLSHYGIELPAASFDARLAKYLLSTVEDNELATIAR  417
                F++ + K ++ TYD+KR+KVLLSH GIEL A+S+DARLA+YLLSTVEDNEL+TIAR
Sbjct  359  ATDSFKQVFQK-PIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIAR  417

Query  418  LYGRTILPTDDEVYGKGAKRALPEQEQLFEHLARKVQVLLETEEPMLEQLRAHDQLDLLL  477
            ++    L  DD VYGKGAKRA+P+++ L+EHLARKV+VLL++   ML++L AH+QLDL  
Sbjct  418  IFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQ  477

Query  478  EMEQPLAFVLAKMEIAGIKVERETLQGMQAENEKTLESLTQEIYDLAGQEFNINSPKQLG  537
            ++E PLA VLAKMEI GIKV+R TLQ+M  +N   +E+LTQEIYD+AGQEFNINSPKQLG
Sbjct  478  NIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLG  537

Query  538  TILFEDMGLPLEYTKKTKTGYSTAVDVLERLAPIAPIVSKILEYRQISKLQSTYIIGLQE  597
            +ILFE M LPLE TKKTKTGYSTAVDVLERLAPIAPIV+KIL+YRQI+KLQSTY+IGLQ+
Sbjct  538  SILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQD  597

Query  598  AIAADGKIHTRYVQDLTQTGRLSSVDPNLQNIPVRLEQGRLIRKAFVPEWADSVLLSSDY  657
             I ADGKIHTRYVQDLTQTGRLSSVDPNLQNIP+RLEQGRLIRKAF P   D+VLLSSDY
Sbjct  598  YILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDY  657

Query  658  SQIELRVLAHISQDEHLIAAFQHGEDIHTATAMRVFGIEKAEDVTPNDRRNAKAVNFGVV  717
            SQIELRVLAHIS DEHLIAAF++G DIHT+TAMRVFGI+KA DVT+NDRRNAKAVNFG+V
Sbjct  658  SQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIV  717

Query  718  YGISDFGLANNLGISRKAAKDYIQTYFERFPGIKNYMETIVREARDKGYVETIYHRRRSL  777
            YGISDFGL+NNLGI+RK +K YI+TYFER+PGIK YME +VREA+DKGYVET++ RRR L
Sbjct  718  YGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRREL  777

Query  778  PDINSRNFNIRNFAERTAINSPIQGSAADILKVAMINLDRALTEKNFKSRMLLQVHDEIV  837
            PDINSRNFN+R+FAERTAINSPIQGSAADILK+AMINLD+AL    F+++MLLQVHDEIV
Sbjct  778  PDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIV  837

Query  838  LEVPNDELTAVRQLVKETMEAAIELAVPLVADENAGQTWYEAK  880
            LEVPNDELTA+++LVK+TMEAA++LAVPL  DE++GQ+WYEAK
Sbjct  838  LEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

57) polA in NC_009009


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score = 1145 bits (4343),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 668/883 (76%), Positives = 791/883 (90%), Gaps = 6/883 (0%)

Query  1    MEKKNKLLLIDGSSVAFRAFFALYNQIDRFKSPSGLHTNAIYGFHLMLNHLLERVQPTHV  60
            ME+KNKLLLIDGSSVAFRAFFALYNQIDRFK+ SGLHTNAIYGFHLML+H++ RV+PTHV
Sbjct  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60

Query  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQLPFIREMLKHLGIHYYDLAQYEADDII  120
            LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQ+++IREML  LGI YY+L +YEADDII
Sbjct  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120

Query  121  GTLDKMAEKTAVPYDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGIT  180
            GTLDKMAE+T VP+DVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMG+T
Sbjct  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180

Query  181  PEQFIDLKALMGDQSDNIPGVTKIGEKTGLKLLLEYGSLENLYENIDQLKASKMKENLIN  240
            P+QFIDLKALMGD+SDNIPGVTKIGEKTGLKLL E+GSLE +YE+ID +K+SKMKENLIN
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  241  DKDKAFLSKTLATINTQAPIEIGLDDLVYKGPQVEALSKFYDEMGFKQLKAQLGT--GQD  298
            D+D+AFLSKTLATINT +PI IGLDD+VY+GP+V +LS+FYDEM+F QLK  L++   Q+
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQE  300

Query  299  PVEVKPIEFTKVTEVTADMLAPEQFFYFEILGDNYHKEEVVGLAWGDSRQIYVGSS-DLL  357
            PV V  I +  VT+V+AD++++E++FYFE L DNYH+E ++G+AWG++ QIY ++   LL
Sbjct  301  PVAV--ISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLL  358

Query  358  QQPLFQEFLTKTALKTYDIKRAKVLLSHYGIELPAAAFDARLAKYLLSTVEDNELVTIAR  417
                F++ + K ++ TYD+KR+KVLLSH GIEL A+++DARLA+YLLSTVEDNEL TIAR
Sbjct  359  ATDSFKQVFQK-PIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIAR  417

Query  418  LYGQTILPTDDEVYGKGAKRALPEQEQLFKHLARKIQVLLETEEPMQEQLRAHDQLDLLL  477
            ++ +  L  DD VYGKGAKRA+P+++ L+ HLARK++VLL++   M ++L AH+QLDL  
Sbjct  418  IFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQ  477

Query  478  EMEQPLAFVLAKMEIAGIKVERETLQGMQAENEKTLESLTQEIYDLAGQEFNINSPKQLG  537
            ++E PLA VLAKMEI GIKV+R TLQ+M  +N   +E+LTQEIYD+AGQEFNINSPKQLG
Sbjct  478  NIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLG  537

Query  538  TILFEDMGLPLEYTKKTKTGYSTAVDVLERLAPIAPIVSKILEYRQISKLQSTYIIGLQE  597
            +ILFE M LPLE TKKTKTGYSTAVDVLERLAPIAPIV+KIL+YRQI+KLQSTY+IGLQ+
Sbjct  538  SILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQD  597

Query  598  AIAADGKIHTRYVQDLTQTGRLSSVDPNLQNIPVRLEQGRLIRKAFVPEWADSVLLSSDY  657
             I ADGKIHTRYVQDLTQTGRLSSVDPNLQNIP+RLEQGRLIRKAF P   D+VLLSSDY
Sbjct  598  YILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDY  657

Query  658  SQIELRVLAHISQDEHLIAAFQHGEDIHTATAMRVFGIEKAEDVTPNDRRNAKAVNFGVV  717
            SQIELRVLAHIS DEHLIAAF++G DIHT+TAMRVFGI+KA DVT+NDRRNAKAVNFG+V
Sbjct  658  SQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIV  717

Query  718  YGISDFGLANNLGISRKAAKDYIQTYFERFPGIKNYMETIVREARDKGYVETIYHRRRSL  777
            YGISDFGL+NNLGI+RK +K YI+TYFER+PGIK YME +VREA+DKGYVET++ RRR L
Sbjct  718  YGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRREL  777

Query  778  PDINSRNFNIRNFAERTAINSPIQGSAADILKVAMINLDRALTEKNFKSRMLLQVHDEIV  837
            PDINSRNFN+R+FAERTAINSPIQGSAADILK+AMINLD+AL    F+++MLLQVHDEIV
Sbjct  778  PDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIV  837

Query  838  LEVPNDELTAVRKLVKETMETAIELAVPLVADENAGQTWYEAK  880
            LEVPNDELTA++KLVK+TME+A++LAVPL  DE++GQ+WYEAK
Sbjct  838  LEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

58) polA in NC_022246


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score = 1142 bits (4330),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 655/881 (75%), Positives = 786/881 (90%), Gaps = 1/881 (0%)

Query  1    MEKKNKLLLIDGSSVAYRAFFALYNQIDRFKSPSGLHTNAIYGFHLMLNHLLERVQPTHI  60
            ME+KNKLLLIDGSSVA+RAFFALYNQIDRFK+ SGLHTNAIYGFHLML+H++ RV+PTH+
Sbjct  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60

Query  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQLPFIREMLQHLGIHYYDLAQYEADDII  120
            LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQ+++IREML  LGI YY+L +YEADDII
Sbjct  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120

Query  121  GTLDKMAEKTAVPYDVTIVSGDKDLIQLTDDNTVVEISKKGVAEFEEFTPAYLMEKMGIS  180
            GTLDKMAE+T VP+DVTIVSGDKDLIQLTD+NTVVEISKKGVAEFEEFTPAYLMEKMG++
Sbjct  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180

Query  181  PVQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLLEYGSLEGIYDHIDQLKQSKMKENLIK  240
            P QFIDLKALMGDKSDNIPGVTKIGEKTGLKLL E+GSLEGIY+HID +K SKMKENLI+
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  241  DKEIAFLSRKLVTIDTQAPIEIGLEDILYQGSDIKQLGRFYDEMGFKQFKQALESEVEPE  300
            D++ AFLS+ L TI+T +PI IGL+DI+Y+G+D+  L++FYDEM+F Q+K++L S++  E
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQE  300

Query  301  EMADIAFEEVMEVRPEMLSADDFFYFEMLGDNYHIDEMVGFAWGNAQKIYVSQDVRLLQQ  360
             +A I+++EV +V ++++SA+D+FYFE L DNYH + ++GFAWG++++IY S D+ LL  
Sbjct  301  PVAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLAT  360

Query  361  PIFKEFLENTALKVYDLKRSKVLLSRLGIELSQLAFDSRLAKYLLSTVDNNEIATIASLY  420
              FK+ +++ ++  YD+KRSKVLLS+LGIEL   ++D+RLA+YLLSTV++NE++TIA ++
Sbjct  361  DSFKQVFQK-PIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIF  419

Query  421  GKTKLDEDEVIYGKGAKRALPEKPILLNHLARKVAVLVETEQPMLDLLRQHDQLNLLYEM  480
                L+ED+ +YGKGAKRA+P+K +LL+HLARKV VL+++   MLD L  H+QL+L  ++
Sbjct  420  TDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNI  479

Query  481  EQPLALVLAKMEIAGIKVERETLQTMQVENERVLTQLTQEIYDLAGEEFNINSPKQLGGI  540
            E PLA VLAKMEI GIKV+R TLQ M  +N  ++  LTQEIYD+AG+EFNINSPKQLG+I
Sbjct  480  ELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSI  539

Query  541  LFEKLGLPTSFTKKTKTGYSTAVDVLERLAPIAPIVEKILEYRQIAKIQSTYVMGLQDWI  600
            LFEK+ LP   TKKTKTGYSTAVDVLERLAPIAPIV KIL+YRQI+K+QSTYV+GLQD I
Sbjct  540  LFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYI  599

Query  601  LADGKIHTRYLQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFVPEWKDSVLLSSDYSQ  660
            LADGKIHTRY+QDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAF P   D+VLLSSDYSQ
Sbjct  600  LADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQ  659

Query  661  IELRVLAHISGDKHLIEAFRHGADIHTSTAMRVFGIEKPEDVTPNDRRNAKAVNFGVVYG  720
            IELRVLAHISGD HLI AF +GADIHTSTAMRVFGI+K+ DVT+NDRRNAKAVNFG+VYG
Sbjct  660  IELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYG  719

Query  721  ISDFGLANNLGISRKEAKSYIDTYFERYPRIKNYMENVVREARDKGYVETLFHRRREIPD  780
            ISDFGL+NNLGI+RK++KSYIDTYFERYP IK YMENVVREA+DKGYVETLF RRRE+PD
Sbjct  720  ISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPD  779

Query  781  INSRNFNVRGFAERTAINSPIQGSAADILKIAMIRLDQALRAGRFKSRMLLQVHDEIVLE  840
            INSRNFNVR+FAERTAINSPIQGSAADILKIAMI LD+AL+AG F+++MLLQVHDEIVLE
Sbjct  780  INSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLE  839

Query  841  VPANELTAIKTLVKEIMESAIELSVPLKADESAGETWYEAK  881
            VP +ELTAIK LVK+ ME+A++L+VPL  DES+G++WYEAK
Sbjct  840  VPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

59) polA in NC_022237


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score = 1141 bits (4328),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 654/881 (75%), Positives = 786/881 (90%), Gaps = 1/881 (0%)

Query  1    MEKKNKLLLIDGSSVAYRAFFALYNQIDRFKSPSGLHTNAIYGFHLMLNHLLERVQPTHI  60
            ME+KNKLLLIDGSSVA+RAFFALYNQIDRFK+ SGLHTNAIYGFHLML+H++ RV+PTH+
Sbjct  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60

Query  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQLPFIREMLQHLGIHYYDLAQYEADDII  120
            LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQ+++IREML  LGI YY+L +YEADDII
Sbjct  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120

Query  121  GTLDKMAEKTAVPYDVTIVSGDKDLIQLTDDNTVVEISKKGVAEFEEFTPAYLMEKMGIS  180
            GTLDKMAE+T VP+DVTIVSGDKDLIQLTD+NTVVEISKKGVAEFEEFTPAYLMEKMG++
Sbjct  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180

Query  181  PVQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLLEYGSLEGIYDHIDQLKQSKMKENLIK  240
            P QFIDLKALMGDKSDNIPGVTKIGEKTGLKLL E+GSLEGIY+HID +K SKMKENLI+
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  241  DKEIAFLSRKLVTIDTQAPIEIGLEDILYQGSDIKQLGRFYDEMGFKQFKQALESEVEPE  300
            D++ AFLS+ L TI+T +PI IGL+DI+Y+G+D+  L++FYDEM+F Q+K++L S++  E
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQE  300

Query  301  EMADIAFEEVMEVRPEMLSADDFFYFEMLGDNYHIDEMVGFAWGNAQKIYVSQDVRLLQQ  360
             +A I+++EV +V ++++SA+D+FYFE L DNYH + ++GFAWG++++IY S D+ LL  
Sbjct  301  PVAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLAT  360

Query  361  PIFKEFLENTALKVYDLKRSKVLLSRLGIELSQLAFDSRLAKYLLSTVDNNEIATIASLY  420
              FK+ +++ ++  YD+KRSKVLLS+LGIEL   ++D+RLA+YLLSTV++NE++TIA ++
Sbjct  361  DSFKQVFQK-PIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIF  419

Query  421  GKTKLDEDEVIYGKGAKRALPEKPILLNHLARKVAVLVETEQPMIDLLRQHDQLNLLYEM  480
                L+ED+ +YGKGAKRA+P+K +LL+HLARKV VL+++   M+D L  H+QL+L  ++
Sbjct  420  TDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNI  479

Query  481  EQPLALVLAKMEIAGIKVERETLQTMQVENERVLTQLTQEIYDLAGEEFNINSPKQLGGI  540
            E PLA VLAKMEI GIKV+R TLQ M  +N  ++  LTQEIYD+AG+EFNINSPKQLG+I
Sbjct  480  ELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSI  539

Query  541  LFEKLGLPTAFTKKTKTGYSTAVDVLERLAPIAPIVEKILEYRQIAKIQSTYVMGLQDWI  600
            LFEK+ LP   TKKTKTGYSTAVDVLERLAPIAPIV KIL+YRQI+K+QSTYV+GLQD I
Sbjct  540  LFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYI  599

Query  601  LADGKIHTRYLQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFVPEWKDSVLLSSDYSQ  660
            LADGKIHTRY+QDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAF P   D+VLLSSDYSQ
Sbjct  600  LADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQ  659

Query  661  IELRVLAHISGDKHLIEAFRHGADIHTSTAMRVFGIEKPEDVTPNDRRNAKAVNFGVVYG  720
            IELRVLAHISGD HLI AF +GADIHTSTAMRVFGI+K+ DVT+NDRRNAKAVNFG+VYG
Sbjct  660  IELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYG  719

Query  721  ISDFGLANNLGISRKEAKSYIDTYFERYPRIKNYMENVVREARDKGYVETLFHRRREIPD  780
            ISDFGL+NNLGI+RK++KSYIDTYFERYP IK YMENVVREA+DKGYVETLF RRRE+PD
Sbjct  720  ISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPD  779

Query  781  INSRNFNVRGFAERTAINSPIQGSAADILKIAMIRLDQALRAGRFKSRMLLQVHDEIVLE  840
            INSRNFNVR+FAERTAINSPIQGSAADILKIAMI LD+AL+AG F+++MLLQVHDEIVLE
Sbjct  780  INSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLE  839

Query  841  VPANELTAIKTLVKEIMESAIELSVPLKADESAGETWYEAK  881
            VP +ELTAIK LVK+ ME+A++L+VPL  DES+G++WYEAK
Sbjct  840  VPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

60) polA in NC_022238


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score = 1140 bits (4325),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 655/881 (75%), Positives = 781/881 (89%), Gaps = 1/881 (0%)

Query  1    MENKNKLLLIDGSSVAYRAFFALYNQIDRFKSPSGLHTNAIYGFHLMLNHLMERVQPTHI  60
            MENKNKLLLIDGSSVA+RAFFALYNQIDRFK+ SGLHTNAIYGFHLML+H+M RV+PTH+
Sbjct  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60

Query  61   LVAFDAGKTTFRTEMYADYKGGRAKTPEEFREQLPFIREMLDKLGIRYYDLDQYEADDII  120
            LVAFDAGKTTFRTEMYADYK+GRAKTP+EFREQ+++IREML  LGI YY+L++YEADDII
Sbjct  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120

Query  121  GTLDKMAENTPVPYDVTIVSGDKDLIQLTDDNTIVEISKKGVAEFEEFTPAYLMEKMGIT  180
            GTLDKMAE T VP+DVTIVSGDKDLIQLTD+NT+VEISKKGVAEFEEFTPAYLMEKMG+T
Sbjct  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180

Query  181  PAQIIDLKALMGDSSDNIPGVTKIGEKTGLKLLLEYGSLEGIYNSIDQMKQSKMKENLIK  240
            P Q+IDLKALMGD SDNIPGVTKIGEKTGLKLL E+GSLEGIY+ ID  K SKMKENLI+
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  241  DKEIAFLSRKLVTIDTQAPIEIGLEDILYQGSDIKQLGRFYDEMGFKQFKQALEAEIEPE  300
            D++ AFLS+ L TI+T +PI IGL+DI+Y+G+D+  L++FYDEM+F Q+K++L +++  E
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQE  300

Query  301  ETTDITFEEVTEVCPEMLSADGFFYFEMLGDNYHIDEMVGFAWGNSQQIYASQDISLLQQ  360
              + I+++EVT+V ++++SA+++FYFE L DNYH + ++GFAWG+++QIYAS D+SLL  
Sbjct  301  PVAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLAT  360

Query  361  PVFKEFLENTALKVYDFKRSKVLLSCLGIELSQPAFDSRLAKYLLSTVDNNEIATIANLY  420
              FK+ +++ ++  YDFKRSKVLLS LGIEL  P++D+RLA+YLLSTV++NE++TIA ++
Sbjct  361  DSFKQVFQK-PIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIF  419

Query  421  GKTRLVEDEVVYGKGAKRALPEKAILLSHLAKKVTVLVETEQPMTDLLRQHDQLNLLYEM  480
                L ED+ VYGKGAKRA+P+K +LL HLA+KV VL+++   M D L  H+QL+L  ++
Sbjct  420  TDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNI  479

Query  481  EQPLAFVLAKMEIAGIKVERETLQTMQTENEEVLARLTQEIYDLAGEEFNINSPKQLGGI  540
            E PLA VLAKMEI GIKV+R TLQ M  +N  ++  LTQEIYD+AG+EFNINSPKQLG+I
Sbjct  480  ELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSI  539

Query  541  LFEKLGLPTSFTKKTKTGYSTAVDVLERLAPIAPIVEKILDYRQIAKIQSTYVMGLQDWI  600
            LFEK+ LP   TKKTKTGYSTAVDVLERLAPIAPIV KILDYRQI+K+QSTYV+GLQD I
Sbjct  540  LFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYI  599

Query  601  LADGKIHTRYLQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFVPEWKDSVLLSSDYSQ  660
            LADGKIHTRY+QDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAF P   D+VLLSSDYSQ
Sbjct  600  LADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQ  659

Query  661  IELRVLAHISGDEHLIEAFRHGADIHTSTAMRVFGIEKPEDVTPNDRRNAKAVNFGVVYG  720
            IELRVLAHISGDEHLI AF +GADIHTSTAMRVFGI+K+ DVT+NDRRNAKAVNFG+VYG
Sbjct  660  IELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYG  719

Query  721  ISDFGLANNLGISRKEAKSYIDTYFERYPGIKNYMENVVREARDKGYVETLFHRRRDIPD  780
            ISDFGL+NNLGI+RK++KSYIDTYFERYPGIK YMENVVREA+DKGYVETLF RRR++PD
Sbjct  720  ISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPD  779

Query  781  INSRNFNVRGFAERTAINSPIQGSAADILKIAMIRLDQALTDRNFKTRMLLQVHDEIVLE  840
            INSRNFNVR+FAERTAINSPIQGSAADILKIAMI LD+AL    F+++MLLQVHDEIVLE
Sbjct  780  INSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLE  839

Query  841  VPENELTAIKTLVKDIMESAIELVVPLKADESAGKTWYEAK  881
            VP++ELTAIK LVKD ME+A++L VPL  DES+G++WYEAK
Sbjct  840  VPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

61) polA in NC_022236


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score = 1140 bits (4325),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 655/881 (75%), Positives = 781/881 (89%), Gaps = 1/881 (0%)

Query  1    MENKNKLLLIDGSSVAYRAFFALYNQIDRFKSPSGLHTNAIYGFHLMLNHLMERVQPTHI  60
            MENKNKLLLIDGSSVA+RAFFALYNQIDRFK+ SGLHTNAIYGFHLML+H+M RV+PTH+
Sbjct  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60

Query  61   LVAFDAGKTTFRTEMYADYKGGRAKTPEEFREQLPFIREMLDKLGIRYYDLDQYEADDII  120
            LVAFDAGKTTFRTEMYADYK+GRAKTP+EFREQ+++IREML  LGI YY+L++YEADDII
Sbjct  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120

Query  121  GTLDKMAENTPVPYDVTIVSGDKDLIQLTDDNTIVEISKKGVAEFEEFTPAYLMEKMGIT  180
            GTLDKMAE T VP+DVTIVSGDKDLIQLTD+NT+VEISKKGVAEFEEFTPAYLMEKMG+T
Sbjct  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180

Query  181  PAQIIDLKALMGDSSDNIPGVTKIGEKTGLKLLLEYGSLEGIYNSIDQMKQSKMKENLIK  240
            P Q+IDLKALMGD SDNIPGVTKIGEKTGLKLL E+GSLEGIY+ ID  K SKMKENLI+
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  241  DKEIAFLSRKLVTIDTQAPIEIGLEDILYQGSDIKQLGRFYDEMGFKQFKQALEAEIEPE  300
            D++ AFLS+ L TI+T +PI IGL+DI+Y+G+D+  L++FYDEM+F Q+K++L +++  E
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQE  300

Query  301  ETTDITFEEVTEVCPEMLSADGFFYFEMLGDNYHIDEMVGFAWGNSQQIYASQDISLLQQ  360
              + I+++EVT+V ++++SA+++FYFE L DNYH + ++GFAWG+++QIYAS D+SLL  
Sbjct  301  PVAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLAT  360

Query  361  PVFKEFLENTALKVYDFKRSKVLLSCLGIELSQPAFDSRLAKYLLSTVDNNEIATIANLY  420
              FK+ +++ ++  YDFKRSKVLLS LGIEL  P++D+RLA+YLLSTV++NE++TIA ++
Sbjct  361  DSFKQVFQK-PIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIF  419

Query  421  GKTRLVEDEVVYGKGAKRALPEKAILLSHLAKKVTVLVETEQPMTDLLRQHDQLNLLYEM  480
                L ED+ VYGKGAKRA+P+K +LL HLA+KV VL+++   M D L  H+QL+L  ++
Sbjct  420  TDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNI  479

Query  481  EQPLAFVLAKMEIAGIKVERETLQTMQTENEEVLARLTQEIYDLAGEEFNINSPKQLGGI  540
            E PLA VLAKMEI GIKV+R TLQ M  +N  ++  LTQEIYD+AG+EFNINSPKQLG+I
Sbjct  480  ELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSI  539

Query  541  LFEKLGLPTSFTKKTKTGYSTAVDVLERLAPIAPIVEKILDYRQIAKIQSTYVMGLQDWI  600
            LFEK+ LP   TKKTKTGYSTAVDVLERLAPIAPIV KILDYRQI+K+QSTYV+GLQD I
Sbjct  540  LFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYI  599

Query  601  LADGKIHTRYLQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFVPEWKDSVLLSSDYSQ  660
            LADGKIHTRY+QDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAF P   D+VLLSSDYSQ
Sbjct  600  LADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQ  659

Query  661  IELRVLAHISGDEHLIEAFRHGADIHTSTAMRVFGIEKPEDVTPNDRRNAKAVNFGVVYG  720
            IELRVLAHISGDEHLI AF +GADIHTSTAMRVFGI+K+ DVT+NDRRNAKAVNFG+VYG
Sbjct  660  IELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYG  719

Query  721  ISDFGLANNLGISRKEAKSYIDTYFERYPGIKNYMENVVREARDKGYVETLFHRRRDIPD  780
            ISDFGL+NNLGI+RK++KSYIDTYFERYPGIK YMENVVREA+DKGYVETLF RRR++PD
Sbjct  720  ISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPD  779

Query  781  INSRNFNVRGFAERTAINSPIQGSAADILKIAMIRLDQALTDRNFKTRMLLQVHDEIVLE  840
            INSRNFNVR+FAERTAINSPIQGSAADILKIAMI LD+AL    F+++MLLQVHDEIVLE
Sbjct  780  INSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLE  839

Query  841  VPENELTAIKTLVKDIMESAIELVVPLKADESAGKTWYEAK  881
            VP++ELTAIK LVKD ME+A++L VPL  DES+G++WYEAK
Sbjct  840  VPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

62) polA in NC_022245


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score = 1140 bits (4325),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 655/881 (75%), Positives = 781/881 (89%), Gaps = 1/881 (0%)

Query  1    MENKNKLLLIDGSSVAYRAFFALYNQIDRFKSPSGLHTNAIYGFHLMLNHLMERVQPTHI  60
            MENKNKLLLIDGSSVA+RAFFALYNQIDRFK+ SGLHTNAIYGFHLML+H+M RV+PTH+
Sbjct  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60

Query  61   LVAFDAGKTTFRTEMYADYKGGRAKTPEEFREQLPFIREMLDKLGIRYYDLDQYEADDII  120
            LVAFDAGKTTFRTEMYADYK+GRAKTP+EFREQ+++IREML  LGI YY+L++YEADDII
Sbjct  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120

Query  121  GTLDKMAENTPVPYDVTIVSGDKDLIQLTDDNTIVEISKKGVAEFEEFTPAYLMEKMGIT  180
            GTLDKMAE T VP+DVTIVSGDKDLIQLTD+NT+VEISKKGVAEFEEFTPAYLMEKMG+T
Sbjct  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180

Query  181  PAQIIDLKALMGDSSDNIPGVTKIGEKTGLKLLLEYGSLEGIYNSIDQMKQSKMKENLIK  240
            P Q+IDLKALMGD SDNIPGVTKIGEKTGLKLL E+GSLEGIY+ ID  K SKMKENLI+
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  241  DKEIAFLSRKLVTIDTQAPIEIGLEDILYQGSDIKQLGRFYDEMGFKQFKQALEAEIEPE  300
            D++ AFLS+ L TI+T +PI IGL+DI+Y+G+D+  L++FYDEM+F Q+K++L +++  E
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQE  300

Query  301  ETTDITFEEVTEVCPEMLSADGFFYFEMLGDNYHIDEMVGFAWGNSQQIYASQDISLLQQ  360
              + I+++EVT+V ++++SA+++FYFE L DNYH + ++GFAWG+++QIYAS D+SLL  
Sbjct  301  PVAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLAT  360

Query  361  PVFKEFLENTALKVYDFKRSKVLLSCLGIELSQPAFDSRLAKYLLSTVDNNEIATIANLY  420
              FK+ +++ ++  YDFKRSKVLLS LGIEL  P++D+RLA+YLLSTV++NE++TIA ++
Sbjct  361  DSFKQVFQK-PIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIF  419

Query  421  GKTRLVEDEVVYGKGAKRALPEKAILLSHLAKKVTVLVETEQPMTDLLRQHDQLNLLYEM  480
                L ED+ VYGKGAKRA+P+K +LL HLA+KV VL+++   M D L  H+QL+L  ++
Sbjct  420  TDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNI  479

Query  481  EQPLAFVLAKMEIAGIKVERETLQTMQTENEEVLARLTQEIYDLAGEEFNINSPKQLGGI  540
            E PLA VLAKMEI GIKV+R TLQ M  +N  ++  LTQEIYD+AG+EFNINSPKQLG+I
Sbjct  480  ELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSI  539

Query  541  LFEKLGLPTSFTKKTKTGYSTAVDVLERLAPIAPIVEKILDYRQIAKIQSTYVMGLQDWI  600
            LFEK+ LP   TKKTKTGYSTAVDVLERLAPIAPIV KILDYRQI+K+QSTYV+GLQD I
Sbjct  540  LFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYI  599

Query  601  LADGKIHTRYLQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFVPEWKDSVLLSSDYSQ  660
            LADGKIHTRY+QDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAF P   D+VLLSSDYSQ
Sbjct  600  LADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQ  659

Query  661  IELRVLAHISGDEHLIEAFRHGADIHTSTAMRVFGIEKPEDVTPNDRRNAKAVNFGVVYG  720
            IELRVLAHISGDEHLI AF +GADIHTSTAMRVFGI+K+ DVT+NDRRNAKAVNFG+VYG
Sbjct  660  IELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYG  719

Query  721  ISDFGLANNLGISRKEAKSYIDTYFERYPGIKNYMENVVREARDKGYVETLFHRRRDIPD  780
            ISDFGL+NNLGI+RK++KSYIDTYFERYPGIK YMENVVREA+DKGYVETLF RRR++PD
Sbjct  720  ISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPD  779

Query  781  INSRNFNVRGFAERTAINSPIQGSAADILKIAMIRLDQALTDRNFKTRMLLQVHDEIVLE  840
            INSRNFNVR+FAERTAINSPIQGSAADILKIAMI LD+AL    F+++MLLQVHDEIVLE
Sbjct  780  INSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLE  839

Query  841  VPENELTAIKTLVKDIMESAIELVVPLKADESAGKTWYEAK  881
            VP++ELTAIK LVKD ME+A++L VPL  DES+G++WYEAK
Sbjct  840  VPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

63) polA in NC_017620


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score = 1140 bits (4322),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 651/879 (75%), Positives = 781/879 (89%), Gaps = 3/879 (0%)

Query  2    KKNKLLLIDGSSVAFRAFFALYNQIDRFKSPTGLHTNAIYGFNLMLDHMMKRIEPTHILV  61
            +KNKLLLIDGSSVAFRAFFALYNQIDRFK+ +GLHTNAIYGF+LMLDHMMKR+ PTH+LV
Sbjct  3    NKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLV  62

Query  62   AFDAGKTTFRTEMYADYKAGRAKTPDEFREQFPFIRQMLDAMGVKHYELAQYEADDIIGT  121
            AFDAGKTTFRTEMYADYKAGRAKTPDEFREQF++IR+ML A+G+  YEL +YEADDIIGT
Sbjct  63   AFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGT  122

Query  122  LDKMAERTEIPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGITPT  181
            LDKMAERTE+PFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMG+TP 
Sbjct  123  LDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPN  182

Query  182  QFIDLKALMGDKSDNIPGVTKIGEKTGLKLLTEFGSLDGIYENIDSMKASKMKENLIADK  241
            QFIDLKALMGDKSDNIPGVTKIGEKTGLKLL EFGSL+GIYE+ID+ K+SKMKENLI D+
Sbjct  183  QFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDR  242

Query  242  EKAFLSRTLATIDTQAPIEIGLDDIVYQGPKVDELGQFYDDMGFKQLRAQLGTTSSQEE-  300
            ++AFLS+TLATI+T +PI IGLDDIVY+GP V  L+QFYD+M+F QL+  L++  +QE  
Sbjct  243  DQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEPV  302

Query  301  AVLDFQIVTEISPAMLKQDQFFYFEILGENYHREDLVGLAWGDKEKIYVGGP-ELLDSPV  359
            AV+ +Q VT++S+ ++  +++FYFE L +NYHRE ++G+AWG+ E+IY +    LL +  
Sbjct  303  AVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLATDS  362

Query  360  LRDFLENQTIKTYDFKRGKVLLDRKEITLPPATFDSRLAKYLLSTVEDNSLTTIANLYGQ  419
            +++ +++  I TYDFKR+KVLL +  I L ++++D+RLA+YLLSTVEDN L+TIA ++ +
Sbjct  363  FKQVFQK-PIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIFTD  421

Query  420  ISLVPDEAVYGKGAKLDLPEREIFFPHLARKVQVLIETEEPMLTKLEENQQLDLLFDMEL  479
            ISL  D++VYGKGAK  +P++++++ HLARKV+VL+++   ML KL  ++QLDL  ++EL
Sbjct  422  ISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNIEL  481

Query  480  PLANVLAKMEIAGIKVEAETLKAMQSENEVLIDQLTKEIYELAGQEFNINSPKQLGTILF  539
            PLANVLAKMEI GIKV+  TL+ M  +N V+I+ LT+EIY++AGQEFNINSPKQLG+ILF
Sbjct  482  PLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSILF  541

Query  540  EEMGLPLEYTKKTKTGYSTAVDVLERLAPIAPVVSKILEYRQITKLQSTYVVGLQDAILE  599
            E M LPLE TKKTKTGYSTAVDVLERLAPIAP+V+KIL+YRQITKLQSTYV+GLQD IL 
Sbjct  542  EKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYILA  601

Query  600  DGKIHTRYVQDLTQTGRLSSTDPNLQNIPVRLEQGRLIRKAFVPSLENSVLLASDYSQIE  659
            DGKIHTRYVQDLTQTGRLSS DPNLQNIP+RLEQGRLIRKAF PS E++VLL+SDYSQIE
Sbjct  602  DGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQIE  661

Query  660  LRVLAHISQDKHLIEAFQQGADIHTSTAMRVFGIEKAEDVTPNDRRNAKAVNFGVVYGIS  719
            LRVLAHIS D HLI AF++GADIHTSTAMRVFGI+KA DVT+NDRRNAKAVNFG+VYGIS
Sbjct  662  LRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGIS  721

Query  720  DFGLSNNLGITRKEAKAYIDTYFERFPGIKNYMETIVREARDKGYVETIYKRRRELPDIN  779
            DFGLSNNLGITRK++K+YIDTYFER+PGIK YME +VREA+DKGYVET++KRRRELPDIN
Sbjct  722  DFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDIN  781

Query  780  SRNFNVRNFAERTAINSPIQGSAADILKVAMINLDKALTEAGLATRMLLQVHDEIVLEVP  839
            SRNFNVR+FAERTAINSPIQGSAADILK+AMINLDKAL  +G+ ++MLLQVHDEIVLEVP
Sbjct  782  SRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEVP  841

Query  840  VAELETVKAMVKETMESAISLSVPLIADENEGSTWYEAK  878
              EL ++K +VK+TME+A+ L+VPL  DE+ G +WYEAK
Sbjct  842  NDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

64) polA in NC_017618


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score = 1139 bits (4320),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 652/879 (75%), Positives = 782/879 (89%), Gaps = 3/879 (0%)

Query  2    KKNKLLLIDGSSVAFRAFFALYNQIDRFKSPTGLHTNAIYGFNLMLDHMMKRIEPTHILV  61
            +KNKLLLIDGSSVAFRAFFALYNQIDRFK+ +GLHTNAIYGF+LMLDHMMKR+ PTH+LV
Sbjct  3    NKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLV  62

Query  62   AFDAGKTTFRTEMYADYKAGRAKTPDEFREQFPFIRQMLDAMGVKHYELDQYEADDIIGT  121
            AFDAGKTTFRTEMYADYKAGRAKTPDEFREQF++IR+ML A+G+  YEL++YEADDIIGT
Sbjct  63   AFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGT  122

Query  122  LDKMAERTEIPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGITPT  181
            LDKMAERTE+PFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMG+TP 
Sbjct  123  LDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPN  182

Query  182  QFIDLKALMGDKSDNIPGVTKIGEKTGLKLLTEFGSLDGIYENIDSMKASKMKENLIADK  241
            QFIDLKALMGDKSDNIPGVTKIGEKTGLKLL EFGSL+GIYE+ID+ K+SKMKENLI D+
Sbjct  183  QFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDR  242

Query  242  EKAFLSRTLATIDTQAPIEIGLDDIVYQGPKVDELGQFYDDMGFKQLRAQLGTTSSQEE-  300
            ++AFLS+TLATI+T +PI IGLDDIVY+GP V  L+QFYD+M+F QL+  L++  +QE  
Sbjct  243  DQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEPV  302

Query  301  AVLDFQIVTEISPAMLKQDQFFYFEILGENYHREDLVGLAWGDKEKIYVGGP-ELLDSPV  359
            AV+ +Q VT++S+ ++  +++FYFE L +NYHRE ++G+AWG+ E+IY +    LL +  
Sbjct  303  AVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLATDS  362

Query  360  LRDFLENQTIKTYDFKRGKVLLDRKEITLPPATFDSRLAKYLLSTVEDNSLTTIANLYGQ  419
            +++ +++  I TYDFKR+KVLL +  I L ++++D+RLA+YLLSTVEDN L+TIA ++ +
Sbjct  363  FKQVFQK-PIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIFTD  421

Query  420  ISLVPDEAVYGKGAKLDLPEREIFFPHLARKVQVLIETEEPMLTKLEENQQLDLLFDMEL  479
            ISL  D++VYGKGAK  +P++++++ HLARKV+VL+++   ML KL  ++QLDL  ++EL
Sbjct  422  ISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNIEL  481

Query  480  PLANVLAKMEIAGIKVEAETLKAMQSENEVLIDQLTKEIYELAGQEFNINSPKQLGIILF  539
            PLANVLAKMEI GIKV+  TL+ M  +N V+I+ LT+EIY++AGQEFNINSPKQLG ILF
Sbjct  482  PLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSILF  541

Query  540  EEMGLPLEYTKKTKTGYSTAVDVLERLAPIAPVVSKILEYRQITKLQSTYVVGLQDAILE  599
            E M LPLE TKKTKTGYSTAVDVLERLAPIAP+V+KIL+YRQITKLQSTYV+GLQD IL 
Sbjct  542  EKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYILA  601

Query  600  DGKIHTRYVQDLTQTGRLSSTDPNLQNIPVRLEQGRLIRKAFVPSLENSVLLASDYSQIE  659
            DGKIHTRYVQDLTQTGRLSS DPNLQNIP+RLEQGRLIRKAF PS E++VLL+SDYSQIE
Sbjct  602  DGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQIE  661

Query  660  LRVLAHISQDKHLIEAFQQGADIHTSTAMRVFGIEKAEDVTPNDRRNAKAVNFGVVYGIS  719
            LRVLAHIS D HLI AF++GADIHTSTAMRVFGI+KA DVT+NDRRNAKAVNFG+VYGIS
Sbjct  662  LRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGIS  721

Query  720  DFGLSNNLGITRKEAKAYIDTYFERFPGIKNYMETIVREARDKGYVETIYKRRRELPDIN  779
            DFGLSNNLGITRK++K+YIDTYFER+PGIK YME +VREA+DKGYVET++KRRRELPDIN
Sbjct  722  DFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDIN  781

Query  780  SRNFNVRNFAERTAINSPIQGSAADILKVAMINLDKALTEAGLATRMLLQVHDEIVLEVP  839
            SRNFNVR+FAERTAINSPIQGSAADILK+AMINLDKAL  +G+ ++MLLQVHDEIVLEVP
Sbjct  782  SRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEVP  841

Query  840  VAELETVKAMVKETMESAISLSVPLIVDENEGPTWYEAK  878
              EL ++K +VK+TME+A+ L+VPL VDE+ G +WYEAK
Sbjct  842  NDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

65) NJAUSS_1282 in NC_020526


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score = 1139 bits (4320),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 652/879 (75%), Positives = 782/879 (89%), Gaps = 3/879 (0%)

Query  2    KKNKLLLIDGSSVAFRAFFALYNQIDRFKSPTGLHTNAIYGFNLMLDHMMKRIEPTHILV  61
            +KNKLLLIDGSSVAFRAFFALYNQIDRFK+ +GLHTNAIYGF+LMLDHMMKR+ PTH+LV
Sbjct  3    NKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLV  62

Query  62   AFDAGKTTFRTEMYADYKAGRAKTPDEFREQFPFIRQMLDAMGVKHYELDQYEADDIIGT  121
            AFDAGKTTFRTEMYADYKAGRAKTPDEFREQF++IR+ML A+G+  YEL++YEADDIIGT
Sbjct  63   AFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGT  122

Query  122  LDKMAERTEIPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGITPT  181
            LDKMAERTE+PFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMG+TP 
Sbjct  123  LDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPN  182

Query  182  QFIDLKALMGDKSDNIPGVTKIGEKTGLKLLTEFGSLDGIYENIDSMKASKMKENLIADK  241
            QFIDLKALMGDKSDNIPGVTKIGEKTGLKLL EFGSL+GIYE+ID+ K+SKMKENLI D+
Sbjct  183  QFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDR  242

Query  242  EKAFLSRTLATIDTQAPIEIGLDDIVYQGPKVDELGQFYDDMGFKQLRAQLGTTSSQEE-  300
            ++AFLS+TLATI+T +PI IGLDDIVY+GP V  L+QFYD+M+F QL+  L++  +QE  
Sbjct  243  DQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEPV  302

Query  301  AVLDFQIVTEISPAMLKQDQFFYFEILGENYHREDLVGLAWGDKEKIYVGGP-ELLDSPV  359
            AV+ +Q VT++S+ ++  +++FYFE L +NYHRE ++G+AWG+ E+IY +    LL +  
Sbjct  303  AVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLATDS  362

Query  360  LRDFLENQTIKTYDFKRGKVLLDRKEITLPPATFDSRLAKYLLSTVEDNSLTTIANLYGQ  419
            +++ +++  I TYDFKR+KVLL +  I L ++++D+RLA+YLLSTVEDN L+TIA ++ +
Sbjct  363  FKQVFQK-PIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIFTD  421

Query  420  ISLVPDEAVYGKGAKLDLPEREIFFPHLARKVQVLIETEEPMLTKLEENQQLDLLFDMEL  479
            ISL  D++VYGKGAK  +P++++++ HLARKV+VL+++   ML KL  ++QLDL  ++EL
Sbjct  422  ISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNIEL  481

Query  480  PLANVLAKMEIAGIKVEAETLKAMQSENEVLIDQLTKEIYELAGQEFNINSPKQLGIILF  539
            PLANVLAKMEI GIKV+  TL+ M  +N V+I+ LT+EIY++AGQEFNINSPKQLG ILF
Sbjct  482  PLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSILF  541

Query  540  EEMGLPLEYTKKTKTGYSTAVDVLERLAPIAPVVSKILEYRQITKLQSTYVVGLQDAILE  599
            E M LPLE TKKTKTGYSTAVDVLERLAPIAP+V+KIL+YRQITKLQSTYV+GLQD IL 
Sbjct  542  EKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYILA  601

Query  600  DGKIHTRYVQDLTQTGRLSSTDPNLQNIPVRLEQGRLIRKAFVPSLENSVLLASDYSQIE  659
            DGKIHTRYVQDLTQTGRLSS DPNLQNIP+RLEQGRLIRKAF PS E++VLL+SDYSQIE
Sbjct  602  DGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQIE  661

Query  660  LRVLAHISQDKHLIEAFQQGADIHTSTAMRVFGIEKAEDVTPNDRRNAKAVNFGVVYGIS  719
            LRVLAHIS D HLI AF++GADIHTSTAMRVFGI+KA DVT+NDRRNAKAVNFG+VYGIS
Sbjct  662  LRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGIS  721

Query  720  DFGLSNNLGITRKEAKAYIDTYFERFPGIKNYMETIVREARDKGYVETIYKRRRELPDIN  779
            DFGLSNNLGITRK++K+YIDTYFER+PGIK YME +VREA+DKGYVET++KRRRELPDIN
Sbjct  722  DFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDIN  781

Query  780  SRNFNVRNFAERTAINSPIQGSAADILKVAMINLDKALTEAGLATRMLLQVHDEIVLEVP  839
            SRNFNVR+FAERTAINSPIQGSAADILK+AMINLDKAL  +G+ ++MLLQVHDEIVLEVP
Sbjct  782  SRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEVP  841

Query  840  VAELETVKAMVKETMESAISLSVPLIVDENEGPTWYEAK  878
              EL ++K +VK+TME+A+ L+VPL VDE+ G +WYEAK
Sbjct  842  NDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

66) polA in NC_017950


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score = 1139 bits (4320),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 652/879 (75%), Positives = 780/879 (89%), Gaps = 3/879 (0%)

Query  2    KKNKLLLIDGSSVAFRAFFALYNQIDRFKSPTGLHTNAIYGFNLMLDHMMKRIEPTHILV  61
            +KNKLLLIDGSSVAFRAFFALYNQIDRFK+ +GLHTNAIYGF+LMLDHMMKR+ PTH+LV
Sbjct  3    NKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLV  62

Query  62   AFDAGKTTFRTEMYADYKAGRAKTPDEFREQFPFIRQMLDAMGVKHYELDQYEADDIIGT  121
            AFDAGKTTFRTEMYADYKAGRAKTPDEFREQF++IR+ML A+G+  YEL++YEADDIIGT
Sbjct  63   AFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGT  122

Query  122  LDKMAERTDVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGITPT  181
            LDKMAERT+VPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMG+TP 
Sbjct  123  LDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPN  182

Query  182  QFIDLKALMGDKSDNIPGVTKIGEKTGLKLLTEFGSLDGIYENIDSMKASKMKENLIADK  241
            QFIDLKALMGDKSDNIPGVTKIGEKTGLKLL EFGSL+GIYE+ID+ K+SKMKENLI D+
Sbjct  183  QFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDR  242

Query  242  EKAFLSRTLATIDTQAPIEIGLDDIVYQGPKVDELGQFYDDMGFKQLRAQLGTTSSQEE-  300
            ++AFLS+TLATI+T +PI IGLDDIVY+GP V  L+QFYD+M+F QL+  L++  +QE  
Sbjct  243  DQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEPV  302

Query  301  AVLDFQIVTEISLAMLKQDQFFYFEILGENYHREDLVGLAWGDKEKIYVGGP-ELLDSPV  359
            AV+ +Q VT++S  ++  +++FYFE L +NYHRE ++G+AWG+ E+IY +    LL +  
Sbjct  303  AVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLATDS  362

Query  360  LRDFLENQTIKTYDFKRGKVLLDRKEITLPPATFDSRLAKYLLSTVEDNSLTTIANLYGQ  419
            +++ +++  I TYDFKR+KVLL +  I L ++++D+RLA+YLLSTVEDN L+TIA ++ +
Sbjct  363  FKQVFQK-PIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIFTD  421

Query  420  TSLVPDEAVYGKGAKLDLPEREVFFPHLARKVQVLIETEEPMLTKLEENQQLDLLFDMEL  479
             SL  D++VYGKGAK  +P+++V++ HLARKV+VL+++   ML KL  ++QLDL  ++EL
Sbjct  422  ISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNIEL  481

Query  480  PLANVLAKMEIAGIKVEAETLKAMQSENEVLIDQLTQEIYELAGQEFNINSPKQLGTILF  539
            PLANVLAKMEI GIKV+  TL+ M  +N V+I+ LTQEIY++AGQEFNINSPKQLG+ILF
Sbjct  482  PLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSILF  541

Query  540  EDMGLPLEYTKKTKTGYSTAVDVLERLAPIAPVVSKILEYRQITKLQSTYVVGLQDAILE  599
            E M LPLE TKKTKTGYSTAVDVLERLAPIAP+V+KIL+YRQITKLQSTYV+GLQD IL 
Sbjct  542  EKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYILA  601

Query  600  DGKIHTRYVQDLTQTGRLSSTDPNLQNIPVRLEQGRLIRKAFVPSLENSVLLASDYSQIE  659
            DGKIHTRYVQDLTQTGRLSS DPNLQNIP+RLEQGRLIRKAF PS E++VLL+SDYSQIE
Sbjct  602  DGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQIE  661

Query  660  LRVLAHISQDKHLIEAFQQGADIHTSTAMRVFGIEKAEDVTPNDRRNAKAVNFGVVYGIS  719
            LRVLAHIS D HLI AF++GADIHTSTAMRVFGI+KA DVT+NDRRNAKAVNFG+VYGIS
Sbjct  662  LRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGIS  721

Query  720  DFGLSNNLGITRKEAKAYIDTYFERFPGIKNYMETIVREARDKGYVETIYKRRRELPDIN  779
            DFGLSNNLGITRK++K+YIDTYFER+PGIK YME +VREA+DKGYVET++KRRRELPDIN
Sbjct  722  DFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDIN  781

Query  780  SRNFNVRNFAERTAINSPIQGSAADILKVAMINLDKALTEAGLATRMLLQVHDEIVLEVP  839
            SRNFNVR+FAERTAINSPIQGSAADILK+AMINLDKAL  +G+ ++MLLQVHDEIVLEVP
Sbjct  782  SRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEVP  841

Query  840  VAELETVKAMVKETMESAISLSVPLIADENEGSTWYEAK  878
              EL ++K +VK+TME+A+ L+VPL  DE+ G +WYEAK
Sbjct  842  NDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

67) polA in NC_022239


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score = 1138 bits (4316),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 653/881 (75%), Positives = 782/881 (89%), Gaps = 1/881 (0%)

Query  1    MENKNKLLLIDGSSVAYRAFFALYNQIDRFKSPSGLHTNAIYGFHLMLNHLMERVQPTHI  60
            MENKNKLLLIDGSSVA+RAFFALYNQIDRFK+ SGLHTNAIYGFHLML+H+M RV+PTH+
Sbjct  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60

Query  61   LVAFDAGKTTFRTEMYADYKGGRAKTPEEFREQLPFIREMLDKLGIRYYDLDQYEADDII  120
            LVAFDAGKTTFRTEMYADYK+GRAKTP+EFREQ+++IREML  LGI YY+L++YEADDII
Sbjct  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120

Query  121  GTLDKMAENTPVPYDVTIVSGDKDLIQLTDDNTIVEISKKGVAEFEEFTPAYLMEKMGIT  180
            GTLDKMAE T VP+DVTIVSGDKDLIQLTD+NT+VEISKKGVAEFEEFTPAYLMEKMG+T
Sbjct  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180

Query  181  PAQIIDLKALMGDSSDNIPGVTKIGEKTGLKLLLEYGSLEGIYNSIDQMKQSKMKENLIK  240
            P Q+IDLKALMGD SDNIPGVTKIGEKTGLKLL E+GSLEGIY+ ID  K SKMKENLI+
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  241  DKEIAFLSRKLVTIDTQAPIEIGLEDILYQGSDIKQLGRFYDEMGFKQFKQALEAEIEPE  300
            D++ AFLS+ L TI+T +PI IGL+DI+Y+G+D+  L++FYDEM+F Q+K++L +++  E
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQE  300

Query  301  ETTDITFKEVTEVCPEMLSADGFFYFEMLGDNYHIDEMVGFAWGNSQQIYASQDISLLQQ  360
              + I+++EVT+V ++++SA+++FYFE L DNYH + ++GFAWG+++QIYAS D+SLL  
Sbjct  301  PVAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLAT  360

Query  361  PVFKEFLENTALKVYDFKRSKVLLSRLGIELSQPAFDSRLAKYLLSTVDNNEIATIANLY  420
              FK+ +++ ++  YDFKRSKVLLS+LGIEL  P++D+RLA+YLLSTV++NE++TIA ++
Sbjct  361  DSFKQVFQK-PIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIF  419

Query  421  GKTRLVEDEVVYGKGAKRALPEKAILLSHLAKKVTVLVETEQPMTDLLRQHDQLNLLYEM  480
                L ED+ VYGKGAKRA+P+K +LL HLA+KV VL+++   M D L  H+QL+L  ++
Sbjct  420  TDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNI  479

Query  481  EQPLAFVLAKMEIAGIKVERETLQTMQTENEEVLARLTQEIYDLAGEEFNINSPKQLGGI  540
            E PLA VLAKMEI GIKV+R TLQ M  +N  ++  LTQEIYD+AG+EFNINSPKQLG+I
Sbjct  480  ELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSI  539

Query  541  LFEKLDLPTSFTKKTKTGYSTAVDVLERLSPIAPIVEKILDYRQIAKIQSTYVMGLQDWI  600
            LFEK++LP   TKKTKTGYSTAVDVLERL+PIAPIV KILDYRQI+K+QSTYV+GLQD I
Sbjct  540  LFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYI  599

Query  601  LADGKIHTRYLQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFVPEWKDSVLLSSDYSQ  660
            LADGKIHTRY+QDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAF P   D+VLLSSDYSQ
Sbjct  600  LADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQ  659

Query  661  IELRVLAHISGDEYLIEAFRHGADIHTSTAMRVFGIEKPEDVTPNDRRNAKAVNFGVVYG  720
            IELRVLAHISGDE LI AF +GADIHTSTAMRVFGI+K+ DVT+NDRRNAKAVNFG+VYG
Sbjct  660  IELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYG  719

Query  721  ISDFGLANNLGISRKEAKSYIDTYFERYPGIKNYMENVVREARDKGYVETLFHRRRDIPD  780
            ISDFGL+NNLGI+RK++KSYIDTYFERYPGIK YMENVVREA+DKGYVETLF RRR++PD
Sbjct  720  ISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPD  779

Query  781  INSRNFNVRGFAERTAINSPIQGSAADILKIAMIRLDQALTDRNFKTRMLLQVHDEIVLE  840
            INSRNFNVR+FAERTAINSPIQGSAADILKIAMI LD+AL    F+++MLLQVHDEIVLE
Sbjct  780  INSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLE  839

Query  841  VPENELTAIKTLVKDIMESAIELVVPLKADESAGKTWYEAK  881
            VP++ELTAIK LVKD ME+A++L VPL  DES+G++WYEAK
Sbjct  840  VPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

68) polA in NC_017621


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score = 1138 bits (4317),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 649/879 (74%), Positives = 781/879 (89%), Gaps = 3/879 (0%)

Query  2    KKNKLLLIDGSSVAFRAFFALYNQIDRFKSPTGLHTNAIYGFNLMLDHMMKRIEPTHILV  61
            +KNKLLLIDGSSVAFRAFFALYNQIDRFK+ +GLHTNAIYGF+LMLDHMMKR+ PTH+LV
Sbjct  3    NKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLV  62

Query  62   AFDAGKTTFRTEMYADYKAGRAKTPDEFREQFPFIRQMLDAMGVKHYELDQYEADDIIGT  121
            AFDAGKTTFRTEMYADYKAGRAKTPDEFREQF++IR+ML A+G+  YEL++YEADDIIGT
Sbjct  63   AFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGT  122

Query  122  LDKMAERTDIPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGITPT  181
            LDKMAERT++PFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMG+TP 
Sbjct  123  LDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPN  182

Query  182  QFIDLKALMGDKSDNIPGVTKIGEKTGLKLLTEFGSLDGIYENIDSMKASKMKENLIADK  241
            QFIDLKALMGDKSDNIPGVTKIGEKTGLKLL EFGSL+GIYE+ID+ K+SKMKENLI D+
Sbjct  183  QFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDR  242

Query  242  EKAFLSRTLATIDTQAPIEIGLDDIVYQGPKVDELGQFYDDMGFKQLRAQLGTTSSQEE-  300
            ++AFLS+TLATI+T +PI IGLDDIVY+GP V  L+QFYD+M+F QL+  L++  +QE  
Sbjct  243  DQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEPV  302

Query  301  AVLDFQIVTEISPAMLKQDQFFYFEILGENYHREDLVGLAWGDKEKIYVGGP-ELLDSPV  359
            AV+ +Q VT++S+ ++  +++FYFE L +NYHRE ++G+AWG+ E+IY +    LL +  
Sbjct  303  AVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLATDS  362

Query  360  LRDFLENQTIKTYDFKRGKVLLDRKEITLPPATFDSRLAKYLLSTVEDNSLTTIANLYGR  419
            +++ +++  I TYDFKR+KVLL +  I L ++++D+RLA+YLLSTVEDN L+TIA ++  
Sbjct  363  FKQVFQK-PIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIFTD  421

Query  420  TSLVPDEAVYGKGAKLDLPEREVFFPHLARKVQVLIETEEPMLTKLEGNQQLDLLFDMEL  479
             SL  D++VYGKGAK  +P+++V++ HLARKV+VL+++   ML KL +++QLDL  ++EL
Sbjct  422  ISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNIEL  481

Query  480  PLANVLAKMEIAGIKVEAETLKAMQSENEVLIDQLTKEIYELAGQEFNINSPKQLGTILF  539
            PLANVLAKMEI GIKV+  TL+ M  +N V+I+ LT+EIY++AGQEFNINSPKQLG+ILF
Sbjct  482  PLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSILF  541

Query  540  EDMGLPLEYTKKTKTGYSTAVDVLERLAPIAPVVSKILEYRQITKLQSTYVVGLQDAILE  599
            E M LPLE TKKTKTGYSTAVDVLERLAPIAP+V+KIL+YRQITKLQSTYV+GLQD IL 
Sbjct  542  EKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYILA  601

Query  600  DGKIHTRYVQDLTQTGRLSSTDPNLQNIPVRLDQGRLIRKAFVPSLENSVLLASDYSQIE  659
            DGKIHTRYVQDLTQTGRLSS DPNLQNIP+RL+QGRLIRKAF PS E++VLL+SDYSQIE
Sbjct  602  DGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQIE  661

Query  660  LRVLAHISQDQHLIEAFQQGADIHTSTAMRVFGIEKAEDVTPNDRRNAKAVNFGVVYGIS  719
            LRVLAHIS D+HLI AF++GADIHTSTAMRVFGI+KA DVT+NDRRNAKAVNFG+VYGIS
Sbjct  662  LRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGIS  721

Query  720  DFGLSNNLGITRKEAKAYIDTYFERFPGIKNYMETIVREARDKGYVETIYKRRRELPDIN  779
            DFGLSNNLGITRK++K+YIDTYFER+PGIK YME +VREA+DKGYVET++KRRRELPDIN
Sbjct  722  DFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDIN  781

Query  780  SRNFNVRNFAERTAINSPIQGSAADILKVAMINLDKALTETGLATRMLLQVHDEIVLEVP  839
            SRNFNVR+FAERTAINSPIQGSAADILK+AMINLDKAL   G+ ++MLLQVHDEIVLEVP
Sbjct  782  SRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEVP  841

Query  840  VAELETVKAMVKETMESAISLSVPLIADENEGSTWYEAK  878
              EL ++K +VK+TME+A+ L+VPL  DE+ G +WYEAK
Sbjct  842  NDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

69) polA in NC_015433


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score = 1138 bits (4314),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 649/879 (74%), Positives = 780/879 (89%), Gaps = 3/879 (0%)

Query  2    KKNKLLLIDGSSVAFRAFFALYNQIDRFKSPTGLHTNAIYGFNLMLDHMMKRIEPTHILV  61
            +KNKLLLIDGSSVAFRAFFALYNQIDRFK+ +GLHTNAIYGF+LMLDHMMKR+ PTH+LV
Sbjct  3    NKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLV  62

Query  62   AFDAGKTTFRTEMYADYKAGRAKTPDEFREQFPFIRQMLDAMGVKHYELAQYEADDIIGT  121
            AFDAGKTTFRTEMYADYKAGRAKTPDEFREQF++IR+ML A+G+  YEL +YEADDIIGT
Sbjct  63   AFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGT  122

Query  122  LDKMAERTEIPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGITPT  181
            LDKMAERTE+PFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMG+TP 
Sbjct  123  LDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPN  182

Query  182  QFIDLKALMGDKSDNIPGVTKIGEKTGLKLLTEFGSLDGIYENIDSMKASKMKENLIADK  241
            QFIDLKALMGDKSDNIPGVTKIGEKTGLKLL EFGSL+GIYE+ID+ K+SKMKENLI D+
Sbjct  183  QFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDR  242

Query  242  EKAFLSRTLATIDTQAPIEIGLDDIVYQGPKVDELGQFYDDMGFKQLRAQLGTTSSQEE-  300
            ++AFLS+TLATI+T +PI IGLDDIVY+GP V  L+QFYD+M+F QL+  L++  +QE  
Sbjct  243  DQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEPV  302

Query  301  AVLDFQIVTEISPAMLKQDQFFYFEILGENYHREDLVGLAWGDKEKIYVGGP-ELLDSPV  359
            AV+ +Q VT++S+ ++  +++FYFE L +NYHRE ++G+AWG+ E+IY +    LL +  
Sbjct  303  AVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLATDS  362

Query  360  LRDFLENQTIKTYDFKRGKVLLDRKEITLPPATFDSRLAKYLLSTVEDNSLTTIANLYGQ  419
            +++ +++  I TYDFKR+KVLL +  I L ++++D+RLA+YLLSTVEDN L+TIA ++ +
Sbjct  363  FKQVFQK-PIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIFTD  421

Query  420  TSLVPDEAIYGKGAKLDLPEREIFFPHLARKVQVLIETEEPMLTKLEENQQLDLLFDMEL  479
             SL  D+++YGKGAK  +P++++++ HLARKV+VL+++   ML KL  ++QLDL  ++EL
Sbjct  422  ISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNIEL  481

Query  480  PLANVLAKMEIAGIKVEAETLKAMQSENEVLIDQLTKEIYELAGQEFNINSPKQLGTILF  539
            PLANVLAKMEI GIKV+  TL+ M  +N V+I+ LT+EIY++AGQEFNINSPKQLG+ILF
Sbjct  482  PLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSILF  541

Query  540  EEMGLPLEYTKKTKTGYSTAVDVLERLAPIAPVVSKILEYRQITKLQSTYVVGLQDAILE  599
            E M LPLE TKKTKTGYSTAVDVLERLAPIAP+V+KIL+YRQITKLQSTYV+GLQD IL 
Sbjct  542  EKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYILA  601

Query  600  DGKIHTRYVQDLTQTGRLSSTDPNLQNIPVRLEQGRLIRKAFVPSLENSVLLASDYSQIE  659
            DGKIHTRYVQDLTQTGRLSS DPNLQNIP+RLEQGRLIRKAF PS E++VLL+SDYSQIE
Sbjct  602  DGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQIE  661

Query  660  LRVLAHISQDKHLIEAFQQGADIHTSTAMRVFGIEKAEDVTPNDRRNAKAVNFGVVYGIS  719
            LRVLAHIS D HLI AF++GADIHTSTAMRVFGI+KA DVT+NDRRNAKAVNFG+VYGIS
Sbjct  662  LRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGIS  721

Query  720  DFGLSNNLGITRKEAKAYIDTYFERFPGIKNYMETIVREARDKGYVETIYKRRRELPDIN  779
            DFGLSNNLGITRK++K+YIDTYFER+PGIK YME +VREA+DKGYVET++KRRRELPDIN
Sbjct  722  DFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDIN  781

Query  780  SRNFNVRNFAERTAINSPIQGSAADILKVAMINLDKALTEAGLATRMLLQVHDEIVLEVP  839
            SRNFNVR+FAERTAINSPIQGSAADILK+AMINLDKAL  +G+ ++MLLQVHDEIVLEVP
Sbjct  782  SRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEVP  841

Query  840  VAELETVKAMVKETMESAISLSVPLIADENEGSTWYEAK  878
              EL ++K +VK+TME+A+ L+VPL  DE+ G +WYEAK
Sbjct  842  NDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

70) polA in NC_018073


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score = 1136 bits (4309),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 650/881 (74%), Positives = 786/881 (90%), Gaps = 1/881 (0%)

Query  1    MEKKNKLLLIDGSSVAYRAFFALYNQIDRFKSPSGLHTNAIYGFHLMINHLLERVQPTHI  60
            ME+KNKLLLIDGSSVA+RAFFALYNQIDRFK+ SGLHTNAIYGFHLM++H++ RV+PTH+
Sbjct  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60

Query  61   LVAFDAGKTTFRTEMYADYKGGRAKTPEEFREQLPFIREMLQHLGIHYYDLAQYEADDII  120
            LVAFDAGKTTFRTEMYADYK+GRAKTP+EFREQ+++IREML  LGI YY+L +YEADDII
Sbjct  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120

Query  121  GTLDKMAEKTAVPYDVTIVSGDKDLIQLTDDNTVVEISKKGVAEFEEFTPAYLMEKMGIS  180
            GTLDKMAE+T VP+DVTIVSGDKDLIQLTD+NTVVEISKKGVAEFEEFTPAYLMEKMG++
Sbjct  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180

Query  181  PVQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLLEYGSLEGIYDHIDQLKQSKMKENLIK  240
            P QFIDLKALMGDKSDNIPGVTKIGEKTGLKLL E+GSLEGIY+HID +K SKMKENLI+
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  241  DKEIAFLSRKLVTIDTQAPIEIGLEDILYQGSDIKQLGRFYDEMGFKQFKQALESEVEPE  300
            D++ AFLS+ L TI+T +PI IGL+DI+Y+G+D+  L++FYDEM+F Q+K++L S++  E
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQE  300

Query  301  EMADIAFEEVMEVRPEMLSADDFFYFEMLGDNYHIDEMVGFAWGNAQKIYVSQDVRLLQQ  360
             +A I+++EV +V ++++SA+D+FYFE L DNYH + ++GFAWG++++IY S D+ LL  
Sbjct  301  PVAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLAT  360

Query  361  PIFKEFLENTALKVYDLKRSKVLLSRLGIELSQLAFDSRLAKYLLSTVDNNEIATIASLY  420
              FK+ +++ ++  YD+KRSKVLLS+LGIEL   ++D+RLA+YLLSTV++NE++TIA ++
Sbjct  361  DSFKQVFQK-PIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIF  419

Query  421  GKTKLDEDEVIYGKGAKRALPEKPILLNHLARKVAVLVETEQPMIDLLRQHDQLNLLYEM  480
                L+ED+ +YGKGAKRA+P+K +LL+HLARKV VL+++   M+D L  H+QL+L  ++
Sbjct  420  TDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNI  479

Query  481  EQPLALVLAKMEIAGIKVERETLQTMQVENERVLTQLTQEIYDLAGEEFNINSPKQLGGI  540
            E PLA VLAKMEI GIKV+R TLQ M  +N  ++  LTQEIYD+AG+EFNINSPKQLG+I
Sbjct  480  ELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSI  539

Query  541  LFEKLGLPTAFTKKTKTGYSTAVDVLERLAPIAPIVEKILEYRQIAKIQSTYVMGLQDWI  600
            LFEK+ LP   TKKTKTGYSTAVDVLERLAPIAPIV KIL+YRQI+K+QSTYV+GLQD I
Sbjct  540  LFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYI  599

Query  601  LADGKIHTRYLQDLTQTGRLSSVYPNLQNIPIRLEQGRLIRKAFVPEWKDSVLLSSDYSQ  660
            LADGKIHTRY+QDLTQTGRLSSV PNLQNIPIRLEQGRLIRKAF P   D+VLLSSDYSQ
Sbjct  600  LADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQ  659

Query  661  IELRVLAHISGDKHLIEAFRHGADIHTSTAMRVFGIEKPEDVTPNDRRNAKAVNFGVVYG  720
            IELRVLAHISGD HLI AF +GADIHTSTAMRVFGI+K+ DVT+NDRRNAKAVNFG+VYG
Sbjct  660  IELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYG  719

Query  721  ISDFGLANNLGISRKEAKSYIDTYFERYPGIKNYMENVVREARDQGYVETLFHRRREIPD  780
            ISDFGL+NNLGI+RK++KSYIDTYFERYPGIK YMENVVREA+D+GYVETLF RRRE+PD
Sbjct  720  ISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPD  779

Query  781  INSRNFNVRGFAERTAINSPIQGSAADILKIAMIRLDQALRAGRFKSRMLLQVHDEIVLE  840
            INSRNFNVR+FAERTAINSPIQGSAADILKIAMI LD+AL+AG F+++MLLQVHDEIVLE
Sbjct  780  INSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLE  839

Query  841  VPANELTAIKTLVKEIMESAIELSVPLKADESAGETWYEAK  881
            VP +ELTAIK LVK+ ME+A++L+VPL  DES+G++WYEAK
Sbjct  840  VPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

71) polA in NC_021213


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score = 1136 bits (4307),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 649/879 (74%), Positives = 780/879 (89%), Gaps = 3/879 (0%)

Query  2    KKNKLLLIDGSSVAFRAFFALYNQIDRFKNANGLHTNAIYGFNLMLDHMMKRIEPTHILV  61
            +KNKLLLIDGSSVAFRAFFALYNQIDRFKN +GLHTNAIYGF+LMLDHMMKR+ PTH+LV
Sbjct  3    NKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLV  62

Query  62   AFDAGKTTFRTEMYADYKAGRAKTPDEFREQFPFIRQMLDAMGVKHYELAQYEADDIIGT  121
            AFDAGKTTFRTEMYADYKAGRAKTPDEFREQF++IR+ML A+G+  YEL +YEADDIIGT
Sbjct  63   AFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGT  122

Query  122  LDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGISPT  181
            LDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMG++P 
Sbjct  123  LDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPN  182

Query  182  QFIDLKALMGDKSDNIPGVTKIGEKTGLKLLTEFGSLDGIYENIDSMKASKMKENLIADK  241
            QFIDLKALMGDKSDNIPGVTKIGEKTGLKLL EFGSL+GIYE+ID+ K+SKMKENLI D+
Sbjct  183  QFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDR  242

Query  242  EKAFLSRTLATIDTQAPIEIGLDDIVYQGPKLEELGQFYDDMGFKQLRAQLGTTSSQEE-  300
            ++AFLS+TLATI+T +PI IGLDDIVY+GP +  L+QFYD+M+F QL+  L++  +QE  
Sbjct  243  DQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEPV  302

Query  301  AVLDFQIVTEISPAMLKQDQFFYFEILGENYHREDLVGLAWGDKEKIYVGGP-ELLDSPV  359
            AV+ +Q VT++S+ ++  +++FYFE L +NYHRE ++G+AWG+ E+IY +    LL +  
Sbjct  303  AVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLATDS  362

Query  360  LRDFLENQTIKTYDFKRGKVLLDRKEITLPPATFDSRLAKYLLSTVEDNSLTTIANLYGQ  419
            +++ +++  I TYDFKR+KVLL +  I L ++++D+RLA+YLLSTVEDN L+TIA ++ +
Sbjct  363  FKQVFQK-PIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIFTD  421

Query  420  TSLVPDEAIYGKGAKLDLPEREIFFPHLARKVQVLIETEEPMLTKLEENQQLDLLFDMEL  479
             SL  D+++YGKGAK  +P++++++ HLARKV+VL+++   ML KL  ++QLDL  ++EL
Sbjct  422  ISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNIEL  481

Query  480  PLANVLAKMEIAGIKVEAETLKAMQSENEVLIDQLTKEIYELAGQEFNINSPKQLGTILF  539
            PLANVLAKMEI GIKV+  TL+ M  +N V+I+ LT+EIY++AGQEFNINSPKQLG+ILF
Sbjct  482  PLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSILF  541

Query  540  EDMGLPLEYTKKTKTGYSTAVDVLERLAPIAPVVSKILEYRQITKLQSTYVVGLQDAILE  599
            E M LPLE TKKTKTGYSTAVDVLERLAPIAP+V+KIL+YRQITKLQSTYV+GLQD IL 
Sbjct  542  EKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYILA  601

Query  600  DGKIHTRYVQDLTQTGRLSSTDPNLQNIPVRLEQGRLIRKAFVPSLENSVLLASDYSQIE  659
            DGKIHTRYVQDLTQTGRLSS DPNLQNIP+RLEQGRLIRKAF PS E++VLL+SDYSQIE
Sbjct  602  DGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQIE  661

Query  660  LRVLAHISQDKHLIEAFQQGADIHTSTAMRVFGIEKAEDVTPNDRRNAKAVNFGVVYGIS  719
            LRVLAHIS D HLI AF++GADIHTSTAMRVFGI+KA DVT+NDRRNAKAVNFG+VYGIS
Sbjct  662  LRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGIS  721

Query  720  DFGLSNNLGITRKEAKAYIDTYFERFPGIKNYMETIVREARDKGYVETIYKRRRELPDIN  779
            DFGLSNNLGITRK++K+YIDTYFER+PGIK YME +VREA+DKGYVET++KRRRELPDIN
Sbjct  722  DFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDIN  781

Query  780  SRNFNVRNFAERTAINSPIQGSAADILKVAMINLDKALTEAGLATRMLLQVHDEIVLEVP  839
            SRNFNVR+FAERTAINSPIQGSAADILK+AMINLDKAL  +G+ ++MLLQVHDEIVLEVP
Sbjct  782  SRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEVP  841

Query  840  VAELETVKAMVKETMESAISLSVPLIADENEGSTWYEAK  878
              EL ++K +VK+TME+A+ L+VPL  DE+ G +WYEAK
Sbjct  842  NDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

72) polA in NC_017576


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score = 1134 bits (4302),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 681/880 (78%), Positives = 783/880 (89%), Gaps = 2/880 (0%)

Query  1    MENKKKLLLIDGSSVAYRAFFALYNQIDRFKNRAGLHTNAIYGFHLMLNHLLERVQPTHV  60
            MENK+KLLLIDGSSVA+RAFFALYNQIDRFKN++GLHTNAIYGFHLML+H++ RV+PTHV
Sbjct  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60

Query  61   LVAFDAGKTTFRTEMYKDYKAGRAKTPDEFREQLPYIREMLSALGITFYDLENYEADDII  120
            LVAFDAGKTTFRTEMY DYKAGRAKTPDEFREQ++YIREML+ALGI++Y+LE+YEADDII
Sbjct  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120

Query  121  GTLDKLAENED-EYDVTIVSGDKDLIQLADNNTTVEISKKGVAEFEEFTPAYLMEKMGIT  179
            GTLDK+AE  +  +DVTIVSGDKDLIQL+D+NT VEISKKGVAEFEEFTPAYLMEKMG+T
Sbjct  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180

Query  180  PKQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLLEYGSLEGVYENIDGMKKSKMKENLIN  239
            P+QFIDLKALMGDKSDNIPGVTKIGEKTGLKLL E+GSLEG+YE+IDG K SKMKENLIN
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  240  DKEQAFLSKTLATINISAPITIGLDDINYQGPDLDKLVPFYDEMGFKQFKDNLGAPKKQE  299
            D++QAFLSKTLATIN ++PITIGLDDI Y+GPD+  L  FYDEM+F Q+K  L++   QE
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQE  300

Query  300  KFDV-SYAEVDSLSADMFTDDQFFYFEILGDNYHVENIIGFAWGNDKAIYASTNldllkd  358
               V SY EV ++SAD+F+ +++FYFE L DNYH E IIGFAWG++  IYAST+L LL  
Sbjct  301  PVAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLAT  360

Query  359  dlfkaalakPIKTYDFKRSKVLLSHLGVDLPAPAFDSRLAKYLLSTVDDNELSTIARLYT  418
            D FK  + KPI TYDFKRSKVLLSHLG++L AP++D+RLA+YLLSTV+DNELSTIAR++T
Sbjct  361  DSFKQVFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIFT  420

Query  419  DYVLDSDEAVYGKGVKRAVPKKAVLLSHLARKIVVLNYSEKVMLDKLTEHQQASLLFDME  478
            D  L+ D++VYGKG KRAVP K VLL HLARK+ VL  S   MLDKLT H+Q  L  ++E
Sbjct  421  DISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNIE  480

Query  479  QPLANVLAKMEIAGISVKKATLQEMEASNQAVIDELTQEIYDLAGMEFNINSPKQLGELL  538
             PLANVLAKMEI GI V++ATLQ+M   N+ +I+ LTQEIYD+AG EFNINSPKQLG +L
Sbjct  481  LPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSIL  540

Query  539  FDKMQLPtsytkktktgystAVDVLERLAPISPIVSKILEYRQIAKLQSTYIVGLQDFIL  598
            F+KMQLP   TKKTKTGYSTAVDVLERLAPI+PIV+KIL+YRQI+KLQSTY++GLQD+IL
Sbjct  541  FEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYIL  600

Query  599  QDGKIHTRYLQDLTQTGRLSSVDPNLQNIPVRLEQGRLIRKAFVPETEDEVLLSSDYSQI  658
             DGKIHTRY+QDLTQTGRLSSVDPNLQNIP+RLEQGRLIRKAF P  ED VLLSSDYSQI
Sbjct  601  ADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQI  660

Query  659  ELRVLAHISNDEHLIAAFREGADIHTSTAMRVFGIEKTEDVTPNDRRNAKAVNFGIVYGI  718
            ELRVLAHIS DEHLIAAF EGADIHTSTAMRVFGI+K+ DVT+NDRRNAKAVNFGIVYGI
Sbjct  661  ELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGI  720

Query  719  SDYGLANNLGIPRKVAKQYIETYFERYPGIKNYMERVVRDAKDKGYVETLFHRRRELPDI  778
            SD+GL+NNLGI RK +K YI+TYFERYPGIK YME VVR+AKDKGYVETLF RRRELPDI
Sbjct  721  SDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDI  780

Query  779  NSRNFNIRQFAERTAINSPIQGSAADILKIAMINLDKALVDGQFKTKMLLQVHDEIILQV  838
            NSRNFN+R FAERTAINSPIQGSAADILKIAMINLDKAL  G F++KMLLQVHDEI+L+V
Sbjct  781  NSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEV  840

Query  839  PKDELEAVKTLVKETMESAIDLSVPLIADENAGQTWYEAK  878
            P+DEL A+K LVK+TME+A+DL+VPL  DE++GQ+WYEAK
Sbjct  841  PNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

73) polA in NC_015215


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score = 1134 bits (4302),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 681/880 (78%), Positives = 783/880 (89%), Gaps = 2/880 (0%)

Query  1    MENKKKLLLIDGSSVAYRAFFALYNQIDRFKNRAGLHTNAIYGFHLMLNHLLERVQPTHV  60
            MENK+KLLLIDGSSVA+RAFFALYNQIDRFKN++GLHTNAIYGFHLML+H++ RV+PTHV
Sbjct  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60

Query  61   LVAFDAGKTTFRTEMYKDYKAGRAKTPDEFREQLPYIREMLSALGITFYDLENYEADDII  120
            LVAFDAGKTTFRTEMY DYKAGRAKTPDEFREQ++YIREML+ALGI++Y+LE+YEADDII
Sbjct  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120

Query  121  GTLDKLAENED-EYDVTIVSGDKDLIQLADNNTTVEISKKGVAEFEEFTPAYLMEKMGIT  179
            GTLDK+AE  +  +DVTIVSGDKDLIQL+D+NT VEISKKGVAEFEEFTPAYLMEKMG+T
Sbjct  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180

Query  180  PKQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLLEYGSLEGVYENIDGMKKSKMKENLIN  239
            P+QFIDLKALMGDKSDNIPGVTKIGEKTGLKLL E+GSLEG+YE+IDG K SKMKENLIN
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  240  DKEQAFLSKTLATINISAPITIGLDDINYQGPDLDKLVPFYDEMGFKQFKDNLGAPKKQE  299
            D++QAFLSKTLATIN ++PITIGLDDI Y+GPD+  L  FYDEM+F Q+K  L++   QE
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQE  300

Query  300  KFDV-SYAEVDSLSADMFTDDQFFYFEILGDNYHVENIIGFAWGNDKAIYASTNldllkd  358
               V SY EV ++SAD+F+ +++FYFE L DNYH E IIGFAWG++  IYAST+L LL  
Sbjct  301  PVAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLAT  360

Query  359  dlfkaalakPIKTYDFKRSKVLLSHLGVDLPAPAFDSRLAKYLLSTVDDNELSTIARLYT  418
            D FK  + KPI TYDFKRSKVLLSHLG++L AP++D+RLA+YLLSTV+DNELSTIAR++T
Sbjct  361  DSFKQVFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIFT  420

Query  419  DYVLDSDEAVYGKGVKRAVPKKAVLLSHLARKIVVLNYSEKVMLDKLTEHQQASLLFDME  478
            D  L+ D++VYGKG KRAVP K VLL HLARK+ VL  S   MLDKLT H+Q  L  ++E
Sbjct  421  DISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNIE  480

Query  479  QPLANVLAKMEIAGISVKKATLQEMEASNQAVIDELTQEIYDLAGMEFNINSPKQLGELL  538
             PLANVLAKMEI GI V++ATLQ+M   N+ +I+ LTQEIYD+AG EFNINSPKQLG +L
Sbjct  481  LPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSIL  540

Query  539  FDKMQLPtsytkktktgystAVDVLERLAPISPIVSKILEYRQIAKLQSTYIVGLQDFIL  598
            F+KMQLP   TKKTKTGYSTAVDVLERLAPI+PIV+KIL+YRQI+KLQSTY++GLQD+IL
Sbjct  541  FEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYIL  600

Query  599  QDGKIHTRYLQDLTQTGRLSSVDPNLQNIPVRLEQGRLIRKAFVPETEDEVLLSSDYSQI  658
             DGKIHTRY+QDLTQTGRLSSVDPNLQNIP+RLEQGRLIRKAF P  ED VLLSSDYSQI
Sbjct  601  ADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQI  660

Query  659  ELRVLAHISNDEHLIAAFREGADIHTSTAMRVFGIEKTEDVTPNDRRNAKAVNFGIVYGI  718
            ELRVLAHIS DEHLIAAF EGADIHTSTAMRVFGI+K+ DVT+NDRRNAKAVNFGIVYGI
Sbjct  661  ELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGI  720

Query  719  SDYGLANNLGIPRKVAKQYIETYFERYPGIKNYMERVVRDAKDKGYVETLFHRRRELPDI  778
            SD+GL+NNLGI RK +K YI+TYFERYPGIK YME VVR+AKDKGYVETLF RRRELPDI
Sbjct  721  SDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDI  780

Query  779  NSRNFNIRQFAERTAINSPIQGSAADILKIAMINLDKALVDGQFKTKMLLQVHDEIILQV  838
            NSRNFN+R FAERTAINSPIQGSAADILKIAMINLDKAL  G F++KMLLQVHDEI+L+V
Sbjct  781  NSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEV  840

Query  839  PKDELEAVKTLVKETMESAIDLSVPLIADENAGQTWYEAK  878
            P+DEL A+K LVK+TME+A+DL+VPL  DE++GQ+WYEAK
Sbjct  841  PNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

74) polA in NC_013798


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score = 1134 bits (4302),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 681/880 (78%), Positives = 783/880 (89%), Gaps = 2/880 (0%)

Query  1    MENKKKLLLIDGSSVAYRAFFALYNQIDRFKNRAGLHTNAIYGFHLMLNHLLERVQPTHV  60
            MENK+KLLLIDGSSVA+RAFFALYNQIDRFKN++GLHTNAIYGFHLML+H++ RV+PTHV
Sbjct  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60

Query  61   LVAFDAGKTTFRTEMYKDYKAGRAKTPDEFREQLPYIREMLSALGITFYDLENYEADDII  120
            LVAFDAGKTTFRTEMY DYKAGRAKTPDEFREQ++YIREML+ALGI++Y+LE+YEADDII
Sbjct  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120

Query  121  GTLDKLAENED-EYDVTIVSGDKDLIQLADNNTTVEISKKGVAEFEEFTPAYLMEKMGIT  179
            GTLDK+AE  +  +DVTIVSGDKDLIQL+D+NT VEISKKGVAEFEEFTPAYLMEKMG+T
Sbjct  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180

Query  180  PKQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLLEYGSLEGVYENIDGMKKSKMKENLIN  239
            P+QFIDLKALMGDKSDNIPGVTKIGEKTGLKLL E+GSLEG+YE+IDG K SKMKENLIN
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  240  DKEQAFLSKTLATINISAPITIGLDDINYQGPDLDKLVPFYDEMGFKQFKDNLGAPKKQE  299
            D++QAFLSKTLATIN ++PITIGLDDI Y+GPD+  L  FYDEM+F Q+K  L++   QE
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQE  300

Query  300  KFDV-SYAEVDSLSADMFTDDQFFYFEILGDNYHVENIIGFAWGNDKAIYASTNldllkd  358
               V SY EV ++SAD+F+ +++FYFE L DNYH E IIGFAWG++  IYAST+L LL  
Sbjct  301  PVAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLAT  360

Query  359  dlfkaalakPIKTYDFKRSKVLLSHLGVDLPAPAFDSRLAKYLLSTVDDNELSTIARLYT  418
            D FK  + KPI TYDFKRSKVLLSHLG++L AP++D+RLA+YLLSTV+DNELSTIAR++T
Sbjct  361  DSFKQVFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIFT  420

Query  419  DYVLDSDEAVYGKGVKRAVPKKAVLLSHLARKIVVLNYSEKVMLDKLTEHQQASLLFDME  478
            D  L+ D++VYGKG KRAVP K VLL HLARK+ VL  S   MLDKLT H+Q  L  ++E
Sbjct  421  DISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNIE  480

Query  479  QPLANVLAKMEIAGISVKKATLQEMEASNQAVIDELTQEIYDLAGMEFNINSPKQLGELL  538
             PLANVLAKMEI GI V++ATLQ+M   N+ +I+ LTQEIYD+AG EFNINSPKQLG +L
Sbjct  481  LPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSIL  540

Query  539  FDKMQLPtsytkktktgystAVDVLERLAPISPIVSKILEYRQIAKLQSTYIVGLQDFIL  598
            F+KMQLP   TKKTKTGYSTAVDVLERLAPI+PIV+KIL+YRQI+KLQSTY++GLQD+IL
Sbjct  541  FEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYIL  600

Query  599  QDGKIHTRYLQDLTQTGRLSSVDPNLQNIPVRLEQGRLIRKAFVPETEDEVLLSSDYSQI  658
             DGKIHTRY+QDLTQTGRLSSVDPNLQNIP+RLEQGRLIRKAF P  ED VLLSSDYSQI
Sbjct  601  ADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQI  660

Query  659  ELRVLAHISNDEHLIAAFREGADIHTSTAMRVFGIEKTEDVTPNDRRNAKAVNFGIVYGI  718
            ELRVLAHIS DEHLIAAF EGADIHTSTAMRVFGI+K+ DVT+NDRRNAKAVNFGIVYGI
Sbjct  661  ELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGI  720

Query  719  SDYGLANNLGIPRKVAKQYIETYFERYPGIKNYMERVVRDAKDKGYVETLFHRRRELPDI  778
            SD+GL+NNLGI RK +K YI+TYFERYPGIK YME VVR+AKDKGYVETLF RRRELPDI
Sbjct  721  SDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDI  780

Query  779  NSRNFNIRQFAERTAINSPIQGSAADILKIAMINLDKALVDGQFKTKMLLQVHDEIILQV  838
            NSRNFN+R FAERTAINSPIQGSAADILKIAMINLDKAL  G F++KMLLQVHDEI+L+V
Sbjct  781  NSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEV  840

Query  839  PKDELEAVKTLVKETMESAIDLSVPLIADENAGQTWYEAK  878
            P+DEL A+K LVK+TME+A+DL+VPL  DE++GQ+WYEAK
Sbjct  841  PNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

75) polA in NC_022244


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score = 1134 bits (4299),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 659/881 (75%), Positives = 786/881 (90%), Gaps = 1/881 (0%)

Query  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKSPSGLHTNAIYGFHLMLNHLIERVQPTHI  60
            MENKNKLLLIDGSSVAFRAFFALYNQIDRFK+ SGLHTNAIYGFHLML+H++ RV+PTH+
Sbjct  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60

Query  61   LVAFDAGKTTFRTEMYADYKGGRAKTPEEFREQLPFIREMLDKLGIRDYDLDQYEADDII  120
            LVAFDAGKTTFRTEMYADYK+GRAKTP+EFREQ+++IREML  LGI  Y+L++YEADDII
Sbjct  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120

Query  121  GTLDKMAENTPVPYDVTIVSGDKDLIQLTDDNTIVEISKKGVAEFEEFTPAYLMEKMGIT  180
            GTLDKMAE T VP+DVTIVSGDKDLIQLTD+NT+VEISKKGVAEFEEFTPAYLMEKMG+T
Sbjct  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180

Query  181  PTQFIDLKALMGDSSDNIPGVTKIGEKTGLKLLLEYGSLEGIYDNIDQMKQSKMKENLIN  240
            P QFIDLKALMGD SDNIPGVTKIGEKTGLKLL E+GSLEGIY++ID  K SKMKENLIN
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  241  DKDIAFLSRTLATIDTQAPIEIGLEDILYRGSDIKQLGRFYDEMGFKQFKQaleaevepe  300
            D+D AFLS+TLATI+T +PI IGL+DI+Y G+D+  L++FYDEM+F Q+K++L +++  E
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQE  300

Query  301  eaadiaFEEVTEVRPEMLSKDDFFYFEMLGDNYHIDEMVGFAWGNAQQIYASQDINLLHQ  360
              A I+++EVT+V ++++S +D+FYFE L DNYH + ++GFAWG+++QIYAS D++LL  
Sbjct  301  PVAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLAT  360

Query  361  PAFKEFLENTALKVYDFKRSKVLLSRLGIELSRPAFDSRLAKYLLSTVDNNEIATIAGLY  420
             +FK+ +++ ++  YDFKRSKVLLS+LGIEL  P++D+RLA+YLLSTV++NE++TIA ++
Sbjct  361  DSFKQVFQK-PIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIF  419

Query  421  GKTKLAEDEAVYGKGAKRALPEKAILLSHLARKVTVLVETEKPMTDLLRQHDQLNLLYEM  480
                L ED++VYGKGAKRA+P+K +LL HLARKV VL+++   M D L  H+QL+L  ++
Sbjct  420  TDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNI  479

Query  481  EQPLAFVLAKMEIAGIKVKRETLQTMQAENEVLLTQLTQDIYELAGEEFNINSPKQLGGI  540
            E PLA VLAKMEI GIKV+R TLQ M  +N V++  LTQ+IY++AG+EFNINSPKQLG+I
Sbjct  480  ELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSI  539

Query  541  LFEKLGLPTSFTKKTKTGYSTAVDVLERLAPIAPIVEKILDYRQIAKIQSTYVTGLQDWI  600
            LFEK+ LP   TKKTKTGYSTAVDVLERLAPIAPIV KILDYRQI+K+QSTYV GLQD I
Sbjct  540  LFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYI  599

Query  601  LADGKIHTRYLQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFVPEWENSVLLSSDYSQ  660
            LADGKIHTRY+QDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAF P  E++VLLSSDYSQ
Sbjct  600  LADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQ  659

Query  661  IELRVLAHISGDEHLIEAFRHGADIHTSTAMRVFNIERPEDVTPNDRRNAKAVNFGVVYG  720
            IELRVLAHISGDEHLI AF +GADIHTSTAMRVF I+++ DVT+NDRRNAKAVNFG+VYG
Sbjct  660  IELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYG  719

Query  721  ISDFGLANNLGISRKEAKSYIDTYFERYPGIKNYMENVVREARDKGYVETLFHRRREIPD  780
            ISDFGL+NNLGI+RK++KSYIDTYFERYPGIK YMENVVREA+DKGYVETLF RRRE+PD
Sbjct  720  ISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPD  779

Query  781  INSRNFNVRGFAERTAINSPIQGSAADILKIAMIRLDQALIDGNFKTRMLLQVHDEIVLE  840
            INSRNFNVR+FAERTAINSPIQGSAADILKIAMI LD+AL  G F+++MLLQVHDEIVLE
Sbjct  780  INSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLE  839

Query  841  VPENELTAIKALVKDIMESAIELSVPLKADESAGKTWYEAK  881
            VP++ELTAIK LVKD ME+A++L+VPL  DES+G++WYEAK
Sbjct  840  VPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

76) SSU05_1378 in NC_009442


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score = 1134 bits (4301),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 648/879 (74%), Positives = 781/879 (89%), Gaps = 3/879 (0%)

Query  2    KKNKLLLIDGSSVAFRAFFALYNQIDRFKNANGLHTNAIYGFNLMLDHMMKRIEPTHILV  61
            +KNKLLLIDGSSVAFRAFFALYNQIDRFKN +GLHTNAIYGF+LMLDHMMKR+ PTH+LV
Sbjct  3    NKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLV  62

Query  62   AFDAGKTTFRTEMYADYKAGRAKTPDEFREQFPFIRQMLDAMGVKHYELDQYEADDIIGT  121
            AFDAGKTTFRTEMYADYKAGRAKTPDEFREQF++IR+ML A+G+  YEL++YEADDIIGT
Sbjct  63   AFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGT  122

Query  122  LDKMAERTDIPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGISPT  181
            LDKMAERT++PFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMG++P 
Sbjct  123  LDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPN  182

Query  182  QFIDLKALMGDKSDNIPGVTKIGEKTGLKLLTEFGSLDGIYENIDSMKASKMKENLIADK  241
            QFIDLKALMGDKSDNIPGVTKIGEKTGLKLL EFGSL+GIYE+ID+ K+SKMKENLI D+
Sbjct  183  QFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDR  242

Query  242  EKAFLSRTLATIDTQAPIEIGLDDIVYQGPKVDELGQFYDDMGFKQLRAQLGTTSSQEE-  300
            ++AFLS+TLATI+T +PI IGLDDIVY+GP V  L+QFYD+M+F QL+  L++  +QE  
Sbjct  243  DQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEPV  302

Query  301  AVLDFQIVTEISPAMLKQDQFFYFEILGENYHREDLVGLAWGDKEKIYVGGP-ELLDSPV  359
            AV+ +Q VT++S+ ++  +++FYFE L +NYHRE ++G+AWG+ E+IY +    LL +  
Sbjct  303  AVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLATDS  362

Query  360  LRDFLESQTIKTYDFKRGKVLLDRKEIKLPPATFDSRLAKYLLSTVEDNSLTTIANLYGQ  419
            +++ ++ + I TYDFKR+KVLL +  I L ++++D+RLA+YLLSTVEDN L+TIA ++ +
Sbjct  363  FKQVFQ-KPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIFTD  421

Query  420  TSLVPDEAVYGKGAKLDLPEREIFFPHLARKVQVLIETEEPMLTKLEENQQLDLLFDMEL  479
             SL  D++VYGKGAK  +P++++++ HLARKV+VL+++   ML KL  ++QLDL  ++EL
Sbjct  422  ISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNIEL  481

Query  480  PLANVLAKMEIAGIKVEAETLKAMQSENEVLIDQLTKEIYELAGQEFNINSPKQLGTILF  539
            PLANVLAKMEI GIKV+  TL+ M  +N V+I+ LT+EIY++AGQEFNINSPKQLG+ILF
Sbjct  482  PLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSILF  541

Query  540  EDMGLPLEYTKKTKTGYSTAVDVLERLAPIAPVVSKILEYRQITKLQSTYVVGLQDAILE  599
            E M LPLE TKKTKTGYSTAVDVLERLAPIAP+V+KIL+YRQITKLQSTYV+GLQD IL 
Sbjct  542  EKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYILA  601

Query  600  DGKIHTRYVQDLTQTGRLSSTDPNLQNIPVRLEQGRLIRKAFVPSLENSVLLASDYSQIE  659
            DGKIHTRYVQDLTQTGRLSS DPNLQNIP+RLEQGRLIRKAF PS E++VLL+SDYSQIE
Sbjct  602  DGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQIE  661

Query  660  LRVLAHISQDQHLIEAFQQGADIHTSTAMRVFGIEKAEYVTPNDRRNAKAVNFGVVYGIS  719
            LRVLAHIS D+HLI AF++GADIHTSTAMRVFGI+KA  VT+NDRRNAKAVNFG+VYGIS
Sbjct  662  LRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGIS  721

Query  720  DFGLSNNLGITRKEAKAYIDTYFERFPGIKNYMETIVREARDKGYVETIYKRRRELPDIN  779
            DFGLSNNLGITRK++K+YIDTYFER+PGIK YME +VREA+DKGYVET++KRRRELPDIN
Sbjct  722  DFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDIN  781

Query  780  SRNFNVRNFAERTAINSPIQGSAADILKVAMINLDKALTEAGLATRMLLQVHDEIVLEVP  839
            SRNFNVR+FAERTAINSPIQGSAADILK+AMINLDKAL  +G+ ++MLLQVHDEIVLEVP
Sbjct  782  SRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEVP  841

Query  840  VAELETVKAMVKETMESAISLSVPLIADENEGSTWYEAK  878
              EL ++K +VK+TME+A+ L+VPL  DE+ G +WYEAK
Sbjct  842  NDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

77) SSU98_1393 in NC_009443


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score = 1134 bits (4301),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 648/879 (74%), Positives = 781/879 (89%), Gaps = 3/879 (0%)

Query  2    KKNKLLLIDGSSVAFRAFFALYNQIDRFKNANGLHTNAIYGFNLMLDHMMKRIEPTHILV  61
            +KNKLLLIDGSSVAFRAFFALYNQIDRFKN +GLHTNAIYGF+LMLDHMMKR+ PTH+LV
Sbjct  3    NKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLV  62

Query  62   AFDAGKTTFRTEMYADYKAGRAKTPDEFREQFPFIRQMLDAMGVKHYELDQYEADDIIGT  121
            AFDAGKTTFRTEMYADYKAGRAKTPDEFREQF++IR+ML A+G+  YEL++YEADDIIGT
Sbjct  63   AFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGT  122

Query  122  LDKMAERTDIPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGISPT  181
            LDKMAERT++PFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMG++P 
Sbjct  123  LDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPN  182

Query  182  QFIDLKALMGDKSDNIPGVTKIGEKTGLKLLTEFGSLDGIYENIDSMKASKMKENLIADK  241
            QFIDLKALMGDKSDNIPGVTKIGEKTGLKLL EFGSL+GIYE+ID+ K+SKMKENLI D+
Sbjct  183  QFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDR  242

Query  242  EKAFLSRTLATIDTQAPIEIGLDDIVYQGPKVDELGQFYDDMGFKQLRAQLGTTSSQEE-  300
            ++AFLS+TLATI+T +PI IGLDDIVY+GP V  L+QFYD+M+F QL+  L++  +QE  
Sbjct  243  DQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEPV  302

Query  301  AVLDFQIVTEISPAMLKQDQFFYFEILGENYHREDLVGLAWGDKEKIYVGGP-ELLDSPV  359
            AV+ +Q VT++S+ ++  +++FYFE L +NYHRE ++G+AWG+ E+IY +    LL +  
Sbjct  303  AVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLATDS  362

Query  360  LRDFLESQTIKTYDFKRGKVLLDRKEIKLPPATFDSRLAKYLLSTVEDNSLTTIANLYGQ  419
            +++ ++ + I TYDFKR+KVLL +  I L ++++D+RLA+YLLSTVEDN L+TIA ++ +
Sbjct  363  FKQVFQ-KPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIFTD  421

Query  420  TSLVPDEAVYGKGAKLDLPEREIFFPHLARKVQVLIETEEPMLTKLEENQQLDLLFDMEL  479
             SL  D++VYGKGAK  +P++++++ HLARKV+VL+++   ML KL  ++QLDL  ++EL
Sbjct  422  ISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNIEL  481

Query  480  PLANVLAKMEIAGIKVEAETLKAMQSENEVLIDQLTKEIYELAGQEFNINSPKQLGTILF  539
            PLANVLAKMEI GIKV+  TL+ M  +N V+I+ LT+EIY++AGQEFNINSPKQLG+ILF
Sbjct  482  PLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSILF  541

Query  540  EDMGLPLEYTKKTKTGYSTAVDVLERLAPIAPVVSKILEYRQITKLQSTYVVGLQDAILE  599
            E M LPLE TKKTKTGYSTAVDVLERLAPIAP+V+KIL+YRQITKLQSTYV+GLQD IL 
Sbjct  542  EKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYILA  601

Query  600  DGKIHTRYVQDLTQTGRLSSTDPNLQNIPVRLEQGRLIRKAFVPSLENSVLLASDYSQIE  659
            DGKIHTRYVQDLTQTGRLSS DPNLQNIP+RLEQGRLIRKAF PS E++VLL+SDYSQIE
Sbjct  602  DGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQIE  661

Query  660  LRVLAHISQDQHLIEAFQQGADIHTSTAMRVFGIEKAEYVTPNDRRNAKAVNFGVVYGIS  719
            LRVLAHIS D+HLI AF++GADIHTSTAMRVFGI+KA  VT+NDRRNAKAVNFG+VYGIS
Sbjct  662  LRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGIS  721

Query  720  DFGLSNNLGITRKEAKAYIDTYFERFPGIKNYMETIVREARDKGYVETIYKRRRELPDIN  779
            DFGLSNNLGITRK++K+YIDTYFER+PGIK YME +VREA+DKGYVET++KRRRELPDIN
Sbjct  722  DFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDIN  781

Query  780  SRNFNVRNFAERTAINSPIQGSAADILKVAMINLDKALTEAGLATRMLLQVHDEIVLEVP  839
            SRNFNVR+FAERTAINSPIQGSAADILK+AMINLDKAL  +G+ ++MLLQVHDEIVLEVP
Sbjct  782  SRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEVP  841

Query  840  VAELETVKAMVKETMESAISLSVPLIADENEGSTWYEAK  878
              EL ++K +VK+TME+A+ L+VPL  DE+ G +WYEAK
Sbjct  842  NDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

78) SSUA7_1222 in NC_017622


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score = 1134 bits (4301),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 648/879 (74%), Positives = 781/879 (89%), Gaps = 3/879 (0%)

Query  2    KKNKLLLIDGSSVAFRAFFALYNQIDRFKNANGLHTNAIYGFNLMLDHMMKRIEPTHILV  61
            +KNKLLLIDGSSVAFRAFFALYNQIDRFKN +GLHTNAIYGF+LMLDHMMKR+ PTH+LV
Sbjct  3    NKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLV  62

Query  62   AFDAGKTTFRTEMYADYKAGRAKTPDEFREQFPFIRQMLDAMGVKHYELDQYEADDIIGT  121
            AFDAGKTTFRTEMYADYKAGRAKTPDEFREQF++IR+ML A+G+  YEL++YEADDIIGT
Sbjct  63   AFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGT  122

Query  122  LDKMAERTDIPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGISPT  181
            LDKMAERT++PFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMG++P 
Sbjct  123  LDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPN  182

Query  182  QFIDLKALMGDKSDNIPGVTKIGEKTGLKLLTEFGSLDGIYENIDSMKASKMKENLIADK  241
            QFIDLKALMGDKSDNIPGVTKIGEKTGLKLL EFGSL+GIYE+ID+ K+SKMKENLI D+
Sbjct  183  QFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDR  242

Query  242  EKAFLSRTLATIDTQAPIEIGLDDIVYQGPKVDELGQFYDDMGFKQLRAQLGTTSSQEE-  300
            ++AFLS+TLATI+T +PI IGLDDIVY+GP V  L+QFYD+M+F QL+  L++  +QE  
Sbjct  243  DQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEPV  302

Query  301  AVLDFQIVTEISPAMLKQDQFFYFEILGENYHREDLVGLAWGDKEKIYVGGP-ELLDSPV  359
            AV+ +Q VT++S+ ++  +++FYFE L +NYHRE ++G+AWG+ E+IY +    LL +  
Sbjct  303  AVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLATDS  362

Query  360  LRDFLESQTIKTYDFKRGKVLLDRKEIKLPPATFDSRLAKYLLSTVEDNSLTTIANLYGQ  419
            +++ ++ + I TYDFKR+KVLL +  I L ++++D+RLA+YLLSTVEDN L+TIA ++ +
Sbjct  363  FKQVFQ-KPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIFTD  421

Query  420  TSLVPDEAVYGKGAKLDLPEREIFFPHLARKVQVLIETEEPMLTKLEENQQLDLLFDMEL  479
             SL  D++VYGKGAK  +P++++++ HLARKV+VL+++   ML KL  ++QLDL  ++EL
Sbjct  422  ISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNIEL  481

Query  480  PLANVLAKMEIAGIKVEAETLKAMQSENEVLIDQLTKEIYELAGQEFNINSPKQLGTILF  539
            PLANVLAKMEI GIKV+  TL+ M  +N V+I+ LT+EIY++AGQEFNINSPKQLG+ILF
Sbjct  482  PLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSILF  541

Query  540  EDMGLPLEYTKKTKTGYSTAVDVLERLAPIAPVVSKILEYRQITKLQSTYVVGLQDAILE  599
            E M LPLE TKKTKTGYSTAVDVLERLAPIAP+V+KIL+YRQITKLQSTYV+GLQD IL 
Sbjct  542  EKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYILA  601

Query  600  DGKIHTRYVQDLTQTGRLSSTDPNLQNIPVRLEQGRLIRKAFVPSLENSVLLASDYSQIE  659
            DGKIHTRYVQDLTQTGRLSS DPNLQNIP+RLEQGRLIRKAF PS E++VLL+SDYSQIE
Sbjct  602  DGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQIE  661

Query  660  LRVLAHISQDQHLIEAFQQGADIHTSTAMRVFGIEKAEYVTPNDRRNAKAVNFGVVYGIS  719
            LRVLAHIS D+HLI AF++GADIHTSTAMRVFGI+KA  VT+NDRRNAKAVNFG+VYGIS
Sbjct  662  LRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGIS  721

Query  720  DFGLSNNLGITRKEAKAYIDTYFERFPGIKNYMETIVREARDKGYVETIYKRRRELPDIN  779
            DFGLSNNLGITRK++K+YIDTYFER+PGIK YME +VREA+DKGYVET++KRRRELPDIN
Sbjct  722  DFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDIN  781

Query  780  SRNFNVRNFAERTAINSPIQGSAADILKVAMINLDKALTEAGLATRMLLQVHDEIVLEVP  839
            SRNFNVR+FAERTAINSPIQGSAADILK+AMINLDKAL  +G+ ++MLLQVHDEIVLEVP
Sbjct  782  SRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEVP  841

Query  840  VAELETVKAMVKETMESAISLSVPLIADENEGSTWYEAK  878
              EL ++K +VK+TME+A+ L+VPL  DE+ G +WYEAK
Sbjct  842  NDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

79) polA in NC_012926


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score = 1134 bits (4301),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 648/879 (74%), Positives = 781/879 (89%), Gaps = 3/879 (0%)

Query  2    KKNKLLLIDGSSVAFRAFFALYNQIDRFKNANGLHTNAIYGFNLMLDHMMKRIEPTHILV  61
            +KNKLLLIDGSSVAFRAFFALYNQIDRFKN +GLHTNAIYGF+LMLDHMMKR+ PTH+LV
Sbjct  3    NKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLV  62

Query  62   AFDAGKTTFRTEMYADYKAGRAKTPDEFREQFPFIRQMLDAMGVKHYELDQYEADDIIGT  121
            AFDAGKTTFRTEMYADYKAGRAKTPDEFREQF++IR+ML A+G+  YEL++YEADDIIGT
Sbjct  63   AFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGT  122

Query  122  LDKMAERTDIPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGISPT  181
            LDKMAERT++PFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMG++P 
Sbjct  123  LDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPN  182

Query  182  QFIDLKALMGDKSDNIPGVTKIGEKTGLKLLTEFGSLDGIYENIDSMKASKMKENLIADK  241
            QFIDLKALMGDKSDNIPGVTKIGEKTGLKLL EFGSL+GIYE+ID+ K+SKMKENLI D+
Sbjct  183  QFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDR  242

Query  242  EKAFLSRTLATIDTQAPIEIGLDDIVYQGPKVDELGQFYDDMGFKQLRAQLGTTSSQEE-  300
            ++AFLS+TLATI+T +PI IGLDDIVY+GP V  L+QFYD+M+F QL+  L++  +QE  
Sbjct  243  DQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEPV  302

Query  301  AVLDFQIVTEISPAMLKQDQFFYFEILGENYHREDLVGLAWGDKEKIYVGGP-ELLDSPV  359
            AV+ +Q VT++S+ ++  +++FYFE L +NYHRE ++G+AWG+ E+IY +    LL +  
Sbjct  303  AVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLATDS  362

Query  360  LRDFLESQTIKTYDFKRGKVLLDRKEIKLPPATFDSRLAKYLLSTVEDNSLTTIANLYGQ  419
            +++ ++ + I TYDFKR+KVLL +  I L ++++D+RLA+YLLSTVEDN L+TIA ++ +
Sbjct  363  FKQVFQ-KPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIFTD  421

Query  420  TSLVPDEAVYGKGAKLDLPEREIFFPHLARKVQVLIETEEPMLTKLEENQQLDLLFDMEL  479
             SL  D++VYGKGAK  +P++++++ HLARKV+VL+++   ML KL  ++QLDL  ++EL
Sbjct  422  ISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNIEL  481

Query  480  PLANVLAKMEIAGIKVEAETLKAMQSENEVLIDQLTKEIYELAGQEFNINSPKQLGTILF  539
            PLANVLAKMEI GIKV+  TL+ M  +N V+I+ LT+EIY++AGQEFNINSPKQLG+ILF
Sbjct  482  PLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSILF  541

Query  540  EDMGLPLEYTKKTKTGYSTAVDVLERLAPIAPVVSKILEYRQITKLQSTYVVGLQDAILE  599
            E M LPLE TKKTKTGYSTAVDVLERLAPIAP+V+KIL+YRQITKLQSTYV+GLQD IL 
Sbjct  542  EKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYILA  601

Query  600  DGKIHTRYVQDLTQTGRLSSTDPNLQNIPVRLEQGRLIRKAFVPSLENSVLLASDYSQIE  659
            DGKIHTRYVQDLTQTGRLSS DPNLQNIP+RLEQGRLIRKAF PS E++VLL+SDYSQIE
Sbjct  602  DGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQIE  661

Query  660  LRVLAHISQDQHLIEAFQQGADIHTSTAMRVFGIEKAEYVTPNDRRNAKAVNFGVVYGIS  719
            LRVLAHIS D+HLI AF++GADIHTSTAMRVFGI+KA  VT+NDRRNAKAVNFG+VYGIS
Sbjct  662  LRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGIS  721

Query  720  DFGLSNNLGITRKEAKAYIDTYFERFPGIKNYMETIVREARDKGYVETIYKRRRELPDIN  779
            DFGLSNNLGITRK++K+YIDTYFER+PGIK YME +VREA+DKGYVET++KRRRELPDIN
Sbjct  722  DFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDIN  781

Query  780  SRNFNVRNFAERTAINSPIQGSAADILKVAMINLDKALTEAGLATRMLLQVHDEIVLEVP  839
            SRNFNVR+FAERTAINSPIQGSAADILK+AMINLDKAL  +G+ ++MLLQVHDEIVLEVP
Sbjct  782  SRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEVP  841

Query  840  VAELETVKAMVKETMESAISLSVPLIADENEGSTWYEAK  878
              EL ++K +VK+TME+A+ L+VPL  DE+ G +WYEAK
Sbjct  842  NDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

80) SSGZ1_1224 in NC_017617


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score = 1134 bits (4301),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 648/879 (74%), Positives = 781/879 (89%), Gaps = 3/879 (0%)

Query  2    KKNKLLLIDGSSVAFRAFFALYNQIDRFKNANGLHTNAIYGFNLMLDHMMKRIEPTHILV  61
            +KNKLLLIDGSSVAFRAFFALYNQIDRFKN +GLHTNAIYGF+LMLDHMMKR+ PTH+LV
Sbjct  3    NKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLV  62

Query  62   AFDAGKTTFRTEMYADYKAGRAKTPDEFREQFPFIRQMLDAMGVKHYELDQYEADDIIGT  121
            AFDAGKTTFRTEMYADYKAGRAKTPDEFREQF++IR+ML A+G+  YEL++YEADDIIGT
Sbjct  63   AFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGT  122

Query  122  LDKMAERTDIPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGISPT  181
            LDKMAERT++PFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMG++P 
Sbjct  123  LDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPN  182

Query  182  QFIDLKALMGDKSDNIPGVTKIGEKTGLKLLTEFGSLDGIYENIDSMKASKMKENLIADK  241
            QFIDLKALMGDKSDNIPGVTKIGEKTGLKLL EFGSL+GIYE+ID+ K+SKMKENLI D+
Sbjct  183  QFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDR  242

Query  242  EKAFLSRTLATIDTQAPIEIGLDDIVYQGPKVDELGQFYDDMGFKQLRAQLGTTSSQEE-  300
            ++AFLS+TLATI+T +PI IGLDDIVY+GP V  L+QFYD+M+F QL+  L++  +QE  
Sbjct  243  DQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEPV  302

Query  301  AVLDFQIVTEISPAMLKQDQFFYFEILGENYHREDLVGLAWGDKEKIYVGGP-ELLDSPV  359
            AV+ +Q VT++S+ ++  +++FYFE L +NYHRE ++G+AWG+ E+IY +    LL +  
Sbjct  303  AVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLATDS  362

Query  360  LRDFLESQTIKTYDFKRGKVLLDRKEIKLPPATFDSRLAKYLLSTVEDNSLTTIANLYGQ  419
            +++ ++ + I TYDFKR+KVLL +  I L ++++D+RLA+YLLSTVEDN L+TIA ++ +
Sbjct  363  FKQVFQ-KPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIFTD  421

Query  420  TSLVPDEAVYGKGAKLDLPEREIFFPHLARKVQVLIETEEPMLTKLEENQQLDLLFDMEL  479
             SL  D++VYGKGAK  +P++++++ HLARKV+VL+++   ML KL  ++QLDL  ++EL
Sbjct  422  ISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNIEL  481

Query  480  PLANVLAKMEIAGIKVEAETLKAMQSENEVLIDQLTKEIYELAGQEFNINSPKQLGTILF  539
            PLANVLAKMEI GIKV+  TL+ M  +N V+I+ LT+EIY++AGQEFNINSPKQLG+ILF
Sbjct  482  PLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSILF  541

Query  540  EDMGLPLEYTKKTKTGYSTAVDVLERLAPIAPVVSKILEYRQITKLQSTYVVGLQDAILE  599
            E M LPLE TKKTKTGYSTAVDVLERLAPIAP+V+KIL+YRQITKLQSTYV+GLQD IL 
Sbjct  542  EKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYILA  601

Query  600  DGKIHTRYVQDLTQTGRLSSTDPNLQNIPVRLEQGRLIRKAFVPSLENSVLLASDYSQIE  659
            DGKIHTRYVQDLTQTGRLSS DPNLQNIP+RLEQGRLIRKAF PS E++VLL+SDYSQIE
Sbjct  602  DGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQIE  661

Query  660  LRVLAHISQDQHLIEAFQQGADIHTSTAMRVFGIEKAEYVTPNDRRNAKAVNFGVVYGIS  719
            LRVLAHIS D+HLI AF++GADIHTSTAMRVFGI+KA  VT+NDRRNAKAVNFG+VYGIS
Sbjct  662  LRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGIS  721

Query  720  DFGLSNNLGITRKEAKAYIDTYFERFPGIKNYMETIVREARDKGYVETIYKRRRELPDIN  779
            DFGLSNNLGITRK++K+YIDTYFER+PGIK YME +VREA+DKGYVET++KRRRELPDIN
Sbjct  722  DFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDIN  781

Query  780  SRNFNVRNFAERTAINSPIQGSAADILKVAMINLDKALTEAGLATRMLLQVHDEIVLEVP  839
            SRNFNVR+FAERTAINSPIQGSAADILK+AMINLDKAL  +G+ ++MLLQVHDEIVLEVP
Sbjct  782  SRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEVP  841

Query  840  VAELETVKAMVKETMESAISLSVPLIADENEGSTWYEAK  878
              EL ++K +VK+TME+A+ L+VPL  DE+ G +WYEAK
Sbjct  842  NDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

81) polA in NC_012925


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score = 1134 bits (4301),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 648/879 (74%), Positives = 781/879 (89%), Gaps = 3/879 (0%)

Query  2    KKNKLLLIDGSSVAFRAFFALYNQIDRFKNANGLHTNAIYGFNLMLDHMMKRIEPTHILV  61
            +KNKLLLIDGSSVAFRAFFALYNQIDRFKN +GLHTNAIYGF+LMLDHMMKR+ PTH+LV
Sbjct  3    NKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLV  62

Query  62   AFDAGKTTFRTEMYADYKAGRAKTPDEFREQFPFIRQMLDAMGVKHYELDQYEADDIIGT  121
            AFDAGKTTFRTEMYADYKAGRAKTPDEFREQF++IR+ML A+G+  YEL++YEADDIIGT
Sbjct  63   AFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGT  122

Query  122  LDKMAERTDIPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGISPT  181
            LDKMAERT++PFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMG++P 
Sbjct  123  LDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPN  182

Query  182  QFIDLKALMGDKSDNIPGVTKIGEKTGLKLLTEFGSLDGIYENIDSMKASKMKENLIADK  241
            QFIDLKALMGDKSDNIPGVTKIGEKTGLKLL EFGSL+GIYE+ID+ K+SKMKENLI D+
Sbjct  183  QFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDR  242

Query  242  EKAFLSRTLATIDTQAPIEIGLDDIVYQGPKVDELGQFYDDMGFKQLRAQLGTTSSQEE-  300
            ++AFLS+TLATI+T +PI IGLDDIVY+GP V  L+QFYD+M+F QL+  L++  +QE  
Sbjct  243  DQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEPV  302

Query  301  AVLDFQIVTEISPAMLKQDQFFYFEILGENYHREDLVGLAWGDKEKIYVGGP-ELLDSPV  359
            AV+ +Q VT++S+ ++  +++FYFE L +NYHRE ++G+AWG+ E+IY +    LL +  
Sbjct  303  AVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLATDS  362

Query  360  LRDFLESQTIKTYDFKRGKVLLDRKEIKLPPATFDSRLAKYLLSTVEDNSLTTIANLYGQ  419
            +++ ++ + I TYDFKR+KVLL +  I L ++++D+RLA+YLLSTVEDN L+TIA ++ +
Sbjct  363  FKQVFQ-KPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIFTD  421

Query  420  TSLVPDEAVYGKGAKLDLPEREIFFPHLARKVQVLIETEEPMLTKLEENQQLDLLFDMEL  479
             SL  D++VYGKGAK  +P++++++ HLARKV+VL+++   ML KL  ++QLDL  ++EL
Sbjct  422  ISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNIEL  481

Query  480  PLANVLAKMEIAGIKVEAETLKAMQSENEVLIDQLTKEIYELAGQEFNINSPKQLGTILF  539
            PLANVLAKMEI GIKV+  TL+ M  +N V+I+ LT+EIY++AGQEFNINSPKQLG+ILF
Sbjct  482  PLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSILF  541

Query  540  EDMGLPLEYTKKTKTGYSTAVDVLERLAPIAPVVSKILEYRQITKLQSTYVVGLQDAILE  599
            E M LPLE TKKTKTGYSTAVDVLERLAPIAP+V+KIL+YRQITKLQSTYV+GLQD IL 
Sbjct  542  EKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYILA  601

Query  600  DGKIHTRYVQDLTQTGRLSSTDPNLQNIPVRLEQGRLIRKAFVPSLENSVLLASDYSQIE  659
            DGKIHTRYVQDLTQTGRLSS DPNLQNIP+RLEQGRLIRKAF PS E++VLL+SDYSQIE
Sbjct  602  DGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQIE  661

Query  660  LRVLAHISQDQHLIEAFQQGADIHTSTAMRVFGIEKAEYVTPNDRRNAKAVNFGVVYGIS  719
            LRVLAHIS D+HLI AF++GADIHTSTAMRVFGI+KA  VT+NDRRNAKAVNFG+VYGIS
Sbjct  662  LRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGIS  721

Query  720  DFGLSNNLGITRKEAKAYIDTYFERFPGIKNYMETIVREARDKGYVETIYKRRRELPDIN  779
            DFGLSNNLGITRK++K+YIDTYFER+PGIK YME +VREA+DKGYVET++KRRRELPDIN
Sbjct  722  DFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDIN  781

Query  780  SRNFNVRNFAERTAINSPIQGSAADILKVAMINLDKALTEAGLATRMLLQVHDEIVLEVP  839
            SRNFNVR+FAERTAINSPIQGSAADILK+AMINLDKAL  +G+ ++MLLQVHDEIVLEVP
Sbjct  782  SRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEVP  841

Query  840  VAELETVKAMVKETMESAISLSVPLIADENEGSTWYEAK  878
              EL ++K +VK+TME+A+ L+VPL  DE+ G +WYEAK
Sbjct  842  NDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

82) YYK_05770 in NC_018526


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score = 1134 bits (4301),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 648/879 (74%), Positives = 781/879 (89%), Gaps = 3/879 (0%)

Query  2    KKNKLLLIDGSSVAFRAFFALYNQIDRFKNANGLHTNAIYGFNLMLDHMMKRIEPTHILV  61
            +KNKLLLIDGSSVAFRAFFALYNQIDRFKN +GLHTNAIYGF+LMLDHMMKR+ PTH+LV
Sbjct  3    NKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLV  62

Query  62   AFDAGKTTFRTEMYADYKAGRAKTPDEFREQFPFIRQMLDAMGVKHYELDQYEADDIIGT  121
            AFDAGKTTFRTEMYADYKAGRAKTPDEFREQF++IR+ML A+G+  YEL++YEADDIIGT
Sbjct  63   AFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGT  122

Query  122  LDKMAERTDIPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGISPT  181
            LDKMAERT++PFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMG++P 
Sbjct  123  LDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPN  182

Query  182  QFIDLKALMGDKSDNIPGVTKIGEKTGLKLLTEFGSLDGIYENIDSMKASKMKENLIADK  241
            QFIDLKALMGDKSDNIPGVTKIGEKTGLKLL EFGSL+GIYE+ID+ K+SKMKENLI D+
Sbjct  183  QFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDR  242

Query  242  EKAFLSRTLATIDTQAPIEIGLDDIVYQGPKVDELGQFYDDMGFKQLRAQLGTTSSQEE-  300
            ++AFLS+TLATI+T +PI IGLDDIVY+GP V  L+QFYD+M+F QL+  L++  +QE  
Sbjct  243  DQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEPV  302

Query  301  AVLDFQIVTEISPAMLKQDQFFYFEILGENYHREDLVGLAWGDKEKIYVGGP-ELLDSPV  359
            AV+ +Q VT++S+ ++  +++FYFE L +NYHRE ++G+AWG+ E+IY +    LL +  
Sbjct  303  AVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLATDS  362

Query  360  LRDFLESQTIKTYDFKRGKVLLDRKEIKLPPATFDSRLAKYLLSTVEDNSLTTIANLYGQ  419
            +++ ++ + I TYDFKR+KVLL +  I L ++++D+RLA+YLLSTVEDN L+TIA ++ +
Sbjct  363  FKQVFQ-KPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIFTD  421

Query  420  TSLVPDEAVYGKGAKLDLPEREIFFPHLARKVQVLIETEEPMLTKLEENQQLDLLFDMEL  479
             SL  D++VYGKGAK  +P++++++ HLARKV+VL+++   ML KL  ++QLDL  ++EL
Sbjct  422  ISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNIEL  481

Query  480  PLANVLAKMEIAGIKVEAETLKAMQSENEVLIDQLTKEIYELAGQEFNINSPKQLGTILF  539
            PLANVLAKMEI GIKV+  TL+ M  +N V+I+ LT+EIY++AGQEFNINSPKQLG+ILF
Sbjct  482  PLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSILF  541

Query  540  EDMGLPLEYTKKTKTGYSTAVDVLERLAPIAPVVSKILEYRQITKLQSTYVVGLQDAILE  599
            E M LPLE TKKTKTGYSTAVDVLERLAPIAP+V+KIL+YRQITKLQSTYV+GLQD IL 
Sbjct  542  EKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYILA  601

Query  600  DGKIHTRYVQDLTQTGRLSSTDPNLQNIPVRLEQGRLIRKAFVPSLENSVLLASDYSQIE  659
            DGKIHTRYVQDLTQTGRLSS DPNLQNIP+RLEQGRLIRKAF PS E++VLL+SDYSQIE
Sbjct  602  DGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQIE  661

Query  660  LRVLAHISQDQHLIEAFQQGADIHTSTAMRVFGIEKAEYVTPNDRRNAKAVNFGVVYGIS  719
            LRVLAHIS D+HLI AF++GADIHTSTAMRVFGI+KA  VT+NDRRNAKAVNFG+VYGIS
Sbjct  662  LRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGIS  721

Query  720  DFGLSNNLGITRKEAKAYIDTYFERFPGIKNYMETIVREARDKGYVETIYKRRRELPDIN  779
            DFGLSNNLGITRK++K+YIDTYFER+PGIK YME +VREA+DKGYVET++KRRRELPDIN
Sbjct  722  DFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDIN  781

Query  780  SRNFNVRNFAERTAINSPIQGSAADILKVAMINLDKALTEAGLATRMLLQVHDEIVLEVP  839
            SRNFNVR+FAERTAINSPIQGSAADILK+AMINLDKAL  +G+ ++MLLQVHDEIVLEVP
Sbjct  782  SRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEVP  841

Query  840  VAELETVKAMVKETMESAISLSVPLIADENEGSTWYEAK  878
              EL ++K +VK+TME+A+ L+VPL  DE+ G +WYEAK
Sbjct  842  NDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

83) polA in NC_012924


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score = 1134 bits (4301),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 648/879 (74%), Positives = 781/879 (89%), Gaps = 3/879 (0%)

Query  2    KKNKLLLIDGSSVAFRAFFALYNQIDRFKNANGLHTNAIYGFNLMLDHMMKRIEPTHILV  61
            +KNKLLLIDGSSVAFRAFFALYNQIDRFKN +GLHTNAIYGF+LMLDHMMKR+ PTH+LV
Sbjct  3    NKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLV  62

Query  62   AFDAGKTTFRTEMYADYKAGRAKTPDEFREQFPFIRQMLDAMGVKHYELDQYEADDIIGT  121
            AFDAGKTTFRTEMYADYKAGRAKTPDEFREQF++IR+ML A+G+  YEL++YEADDIIGT
Sbjct  63   AFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGT  122

Query  122  LDKMAERTDIPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGISPT  181
            LDKMAERT++PFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMG++P 
Sbjct  123  LDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPN  182

Query  182  QFIDLKALMGDKSDNIPGVTKIGEKTGLKLLTEFGSLDGIYENIDSMKASKMKENLIADK  241
            QFIDLKALMGDKSDNIPGVTKIGEKTGLKLL EFGSL+GIYE+ID+ K+SKMKENLI D+
Sbjct  183  QFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDR  242

Query  242  EKAFLSRTLATIDTQAPIEIGLDDIVYQGPKVDELGQFYDDMGFKQLRAQLGTTSSQEE-  300
            ++AFLS+TLATI+T +PI IGLDDIVY+GP V  L+QFYD+M+F QL+  L++  +QE  
Sbjct  243  DQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEPV  302

Query  301  AVLDFQIVTEISPAMLKQDQFFYFEILGENYHREDLVGLAWGDKEKIYVGGP-ELLDSPV  359
            AV+ +Q VT++S+ ++  +++FYFE L +NYHRE ++G+AWG+ E+IY +    LL +  
Sbjct  303  AVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLATDS  362

Query  360  LRDFLESQTIKTYDFKRGKVLLDRKEIKLPPATFDSRLAKYLLSTVEDNSLTTIANLYGQ  419
            +++ ++ + I TYDFKR+KVLL +  I L ++++D+RLA+YLLSTVEDN L+TIA ++ +
Sbjct  363  FKQVFQ-KPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIFTD  421

Query  420  TSLVPDEAVYGKGAKLDLPEREIFFPHLARKVQVLIETEEPMLTKLEENQQLDLLFDMEL  479
             SL  D++VYGKGAK  +P++++++ HLARKV+VL+++   ML KL  ++QLDL  ++EL
Sbjct  422  ISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNIEL  481

Query  480  PLANVLAKMEIAGIKVEAETLKAMQSENEVLIDQLTKEIYELAGQEFNINSPKQLGTILF  539
            PLANVLAKMEI GIKV+  TL+ M  +N V+I+ LT+EIY++AGQEFNINSPKQLG+ILF
Sbjct  482  PLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSILF  541

Query  540  EDMGLPLEYTKKTKTGYSTAVDVLERLAPIAPVVSKILEYRQITKLQSTYVVGLQDAILE  599
            E M LPLE TKKTKTGYSTAVDVLERLAPIAP+V+KIL+YRQITKLQSTYV+GLQD IL 
Sbjct  542  EKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYILA  601

Query  600  DGKIHTRYVQDLTQTGRLSSTDPNLQNIPVRLEQGRLIRKAFVPSLENSVLLASDYSQIE  659
            DGKIHTRYVQDLTQTGRLSS DPNLQNIP+RLEQGRLIRKAF PS E++VLL+SDYSQIE
Sbjct  602  DGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQIE  661

Query  660  LRVLAHISQDQHLIEAFQQGADIHTSTAMRVFGIEKAEYVTPNDRRNAKAVNFGVVYGIS  719
            LRVLAHIS D+HLI AF++GADIHTSTAMRVFGI+KA  VT+NDRRNAKAVNFG+VYGIS
Sbjct  662  LRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGIS  721

Query  720  DFGLSNNLGITRKEAKAYIDTYFERFPGIKNYMETIVREARDKGYVETIYKRRRELPDIN  779
            DFGLSNNLGITRK++K+YIDTYFER+PGIK YME +VREA+DKGYVET++KRRRELPDIN
Sbjct  722  DFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDIN  781

Query  780  SRNFNVRNFAERTAINSPIQGSAADILKVAMINLDKALTEAGLATRMLLQVHDEIVLEVP  839
            SRNFNVR+FAERTAINSPIQGSAADILK+AMINLDKAL  +G+ ++MLLQVHDEIVLEVP
Sbjct  782  SRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEVP  841

Query  840  VAELETVKAMVKETMESAISLSVPLIADENEGSTWYEAK  878
              EL ++K +VK+TME+A+ L+VPL  DE+ G +WYEAK
Sbjct  842  NDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

84) SSU12_1273 in NC_017619


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score = 1134 bits (4301),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 648/879 (74%), Positives = 781/879 (89%), Gaps = 3/879 (0%)

Query  2    KKNKLLLIDGSSVAFRAFFALYNQIDRFKNANGLHTNAIYGFNLMLDHMMKRIEPTHILV  61
            +KNKLLLIDGSSVAFRAFFALYNQIDRFKN +GLHTNAIYGF+LMLDHMMKR+ PTH+LV
Sbjct  3    NKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLV  62

Query  62   AFDAGKTTFRTEMYADYKAGRAKTPDEFREQFPFIRQMLDAMGVKHYELDQYEADDIIGT  121
            AFDAGKTTFRTEMYADYKAGRAKTPDEFREQF++IR+ML A+G+  YEL++YEADDIIGT
Sbjct  63   AFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGT  122

Query  122  LDKMAERTDIPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGISPT  181
            LDKMAERT++PFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMG++P 
Sbjct  123  LDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPN  182

Query  182  QFIDLKALMGDKSDNIPGVTKIGEKTGLKLLTEFGSLDGIYENIDSMKASKMKENLIADK  241
            QFIDLKALMGDKSDNIPGVTKIGEKTGLKLL EFGSL+GIYE+ID+ K+SKMKENLI D+
Sbjct  183  QFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDR  242

Query  242  EKAFLSRTLATIDTQAPIEIGLDDIVYQGPKVDELGQFYDDMGFKQLRAQLGTTSSQEE-  300
            ++AFLS+TLATI+T +PI IGLDDIVY+GP V  L+QFYD+M+F QL+  L++  +QE  
Sbjct  243  DQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEPV  302

Query  301  AVLDFQIVTEISPAMLKQDQFFYFEILGENYHREDLVGLAWGDKEKIYVGGP-ELLDSPV  359
            AV+ +Q VT++S+ ++  +++FYFE L +NYHRE ++G+AWG+ E+IY +    LL +  
Sbjct  303  AVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLATDS  362

Query  360  LRDFLESQTIKTYDFKRGKVLLDRKEIKLPPATFDSRLAKYLLSTVEDNSLTTIANLYGQ  419
            +++ ++ + I TYDFKR+KVLL +  I L ++++D+RLA+YLLSTVEDN L+TIA ++ +
Sbjct  363  FKQVFQ-KPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIFTD  421

Query  420  TSLVPDEAVYGKGAKLDLPEREIFFPHLARKVQVLIETEEPMLTKLEENQQLDLLFDMEL  479
             SL  D++VYGKGAK  +P++++++ HLARKV+VL+++   ML KL  ++QLDL  ++EL
Sbjct  422  ISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNIEL  481

Query  480  PLANVLAKMEIAGIKVEAETLKAMQSENEVLIDQLTKEIYELAGQEFNINSPKQLGTILF  539
            PLANVLAKMEI GIKV+  TL+ M  +N V+I+ LT+EIY++AGQEFNINSPKQLG+ILF
Sbjct  482  PLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSILF  541

Query  540  EDMGLPLEYTKKTKTGYSTAVDVLERLAPIAPVVSKILEYRQITKLQSTYVVGLQDAILE  599
            E M LPLE TKKTKTGYSTAVDVLERLAPIAP+V+KIL+YRQITKLQSTYV+GLQD IL 
Sbjct  542  EKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYILA  601

Query  600  DGKIHTRYVQDLTQTGRLSSTDPNLQNIPVRLEQGRLIRKAFVPSLENSVLLASDYSQIE  659
            DGKIHTRYVQDLTQTGRLSS DPNLQNIP+RLEQGRLIRKAF PS E++VLL+SDYSQIE
Sbjct  602  DGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQIE  661

Query  660  LRVLAHISQDQHLIEAFQQGADIHTSTAMRVFGIEKAEYVTPNDRRNAKAVNFGVVYGIS  719
            LRVLAHIS D+HLI AF++GADIHTSTAMRVFGI+KA  VT+NDRRNAKAVNFG+VYGIS
Sbjct  662  LRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGIS  721

Query  720  DFGLSNNLGITRKEAKAYIDTYFERFPGIKNYMETIVREARDKGYVETIYKRRRELPDIN  779
            DFGLSNNLGITRK++K+YIDTYFER+PGIK YME +VREA+DKGYVET++KRRRELPDIN
Sbjct  722  DFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDIN  781

Query  780  SRNFNVRNFAERTAINSPIQGSAADILKVAMINLDKALTEAGLATRMLLQVHDEIVLEVP  839
            SRNFNVR+FAERTAINSPIQGSAADILK+AMINLDKAL  +G+ ++MLLQVHDEIVLEVP
Sbjct  782  SRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEVP  841

Query  840  VAELETVKAMVKETMESAISLSVPLIADENEGSTWYEAK  878
              EL ++K +VK+TME+A+ L+VPL  DE+ G +WYEAK
Sbjct  842  NDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

85) polA in NC_015600


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score = 1133 bits (4298),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 679/880 (78%), Positives = 785/880 (90%), Gaps = 2/880 (0%)

Query  1    MENKKKLLLIDGSSVAYRAFFALYNQIDRFKNRAGLHTNAIYGFHLMLNHLLERVQPTHV  60
            MENK+KLLLIDGSSVA+RAFFALYNQIDRFKN++GLHTNAIYGFHLML+H++ RV+PTHV
Sbjct  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60

Query  61   LVAFDAGKTTFRTEMYKDYKAGRAKTPDEFREQLPYIREMLSALGITFYDLENYEADDII  120
            LVAFDAGKTTFRTEMY DYKAGRAKTPDEFREQ++YIREML+ALGI++Y+LE+YEADDII
Sbjct  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120

Query  121  GTLDKLAENED-EYDVTIVSGDKDLIQLADNNTTVEISKKGVAEFEEFTPAYLMEKIGIT  179
            GTLDK+AE  +  +DVTIVSGDKDLIQL+D+NT VEISKKGVAEFEEFTPAYLMEK+G+T
Sbjct  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180

Query  180  PKQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLLEYGSLEGVYENIDGMKKSKMKENLIN  239
            P+QFIDLKALMGDKSDNIPGVTKIGEKTGLKLL E+GSLEG+YE+IDG K SKMKENLIN
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  240  DKEQAFLSKTLATINISAPITIGLDDIDYQGPDLDKLVPFYDEMGFKQFKDNLGAPKKQE  299
            D++QAFLSKTLATIN ++PITIGLDDI Y+GPD+  L  FYDEM+F Q+K  L++   QE
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQE  300

Query  300  KFDV-SYTEVDSLSADMFADDQFFYFEILGDNYHVENIIGFAWGNDKAIYASTNldllkd  358
               V SY EV ++SAD+F+ +++FYFE L DNYH E IIGFAWG++  IYAST+L LL  
Sbjct  301  PVAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLAT  360

Query  359  dlfkaalakPIKTYDFKRSKVLLSHFGVDLPAPAFDSRLAKYLLSTVDDNELSTIARLYT  418
            D FK  + KPI TYDFKRSKVLLSH+G++L AP++D+RLA+YLLSTV+DNELSTIAR++T
Sbjct  361  DSFKQVFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIFT  420

Query  419  DYVLDSDEAVYGKGVKRAVPEKSVLLSHLARKIVVLNHSEKVMLDKLTEHQQASLLFDME  478
            D  L+ D++VYGKG KRAVP+K VLL HLARK+ VL +S   MLDKLT H+Q  L  ++E
Sbjct  421  DISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNIE  480

Query  479  QPLANVLAKMEIAGISVKKATLQEMEASNQAVIDELTQEIYDLAGMEFNINSPKQLGELL  538
             PLANVLAKMEI GI V++ATLQ+M   N+ +I+ LTQEIYD+AG EFNINSPKQLG +L
Sbjct  481  LPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSIL  540

Query  539  FDKMQLPtsytkktktgystAVDVLERLAPISPIVSKILEYRQIAKLQSTYIVGLQDFIL  598
            F+KMQLP   TKKTKTGYSTAVDVLERLAPI+PIV+KIL+YRQI+KLQSTY++GLQD+IL
Sbjct  541  FEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYIL  600

Query  599  QDGKIHTRYLQDLTQTGRLSSVDPNLQNIPVRLEQGRLIRKAFVPETEDEVLLSSDYSQI  658
             DGKIHTRY+QDLTQTGRLSSVDPNLQNIP+RLEQGRLIRKAF P  ED VLLSSDYSQI
Sbjct  601  ADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQI  660

Query  659  ELRVLAHISNDEHLIAAFREGADIHTSTAMRVFGIEKTEDVTPNDRRNAKAVNFGIVYGI  718
            ELRVLAHIS DEHLIAAF EGADIHTSTAMRVFGI+K+ DVT+NDRRNAKAVNFGIVYGI
Sbjct  661  ELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGI  720

Query  719  SDYGLANNLGIPRKVAKQYIETYFERYPGIKNYMERVVRDAKDKGYVETLFHRRRELPDI  778
            SD+GL+NNLGI RK +K YI+TYFERYPGIK YME VVR+AKDKGYVETLF RRRELPDI
Sbjct  721  SDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDI  780

Query  779  NSRNFNIRQFAERTAINSPIQGSAADILKIAMINLDKALVDGQFKTKMLLQVHDEIILQV  838
            NSRNFN+R FAERTAINSPIQGSAADILKIAMINLDKAL  G F++KMLLQVHDEI+L+V
Sbjct  781  NSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEV  840

Query  839  PKDELEAVKTLVKETMESAIDLSVPLIADENAGQTWYEAK  878
            P+DEL A+K LVK+TME+A+DL+VPL  DE++GQ+WYEAK
Sbjct  841  PNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

86) KE3_1916 in NC_021900


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score = 1132 bits (4291),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 680/880 (78%), Positives = 781/880 (89%), Gaps = 2/880 (0%)

Query  7    MENKKKLLLIDGSSVAYRAFFALYNQIDRFKNRAGLHTNAIYGFHLMLNHLLERIQPTHV  66
            MENK+KLLLIDGSSVA+RAFFALYNQIDRFKN++GLHTNAIYGFHLML+H++ R++PTHV
Sbjct  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60

Query  67   LVAFDAGKTTFRTEMYKDYKAGRAKTPDEFREQLPYIREMLTALGINWYELENYEADDII  126
            LVAFDAGKTTFRTEMY DYKAGRAKTPDEFREQ++YIREMLTALGI  YELE+YEADDII
Sbjct  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120

Query  127  GTLDKLAENED-EYDVTIVSGDKDLIQLADNNTTVEISKKGVAEFEEFTPTYLMEKMGIT  185
            GTLDK+AE  +  +DVTIVSGDKDLIQL+D+NT VEISKKGVAEFEEFTP+YLMEKMG+T
Sbjct  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180

Query  186  PKQFIDLKALMGDKSDNIPGVTKVGEKTGLKLLLEYGSLEGVYENIDGMKKSKMKENLIN  245
            P+QFIDLKALMGDKSDNIPGVTK+GEKTGLKLL E+GSLEG+YE+IDG K SKMKENLIN
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  246  DKEQAFLSKTLATINITAPIAIGLDDINYSGPDLKKLVPFYDEMGFKQFKDNLGATKKQE  305
            D++QAFLSKTLATIN ++PI+IGLDDI Y+GPD+  L  FYDEM+F Q+K  L++   QE
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQE  300

Query  306  KFDV-SYTEVDSLSADMFTDDQFFYFEILGDNYHIENIIGFAWGNDKAIYASTNlellkd  364
               V SY EV ++SAD+F+ +++FYFE L DNYH E IIGFAWG++  IYAST+L LL  
Sbjct  301  PVAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLAT  360

Query  365  dlfkaalakPIKTYDFKRSKVLLSHLGIDLPAPAFDSRLAKYLLSTVDDNELSTIARLYT  424
            D FK  + KPI TYDFKRSKVLLSHLGI+L AP++D+RLA+YLLSTV+DNELSTIAR++T
Sbjct  361  DSFKQVFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIFT  420

Query  425  EYVLDSDEAVYGKGAKRAVPDKAVLLSHLARKIVVLNHSEKAMLDKLTEHQQASLLFDME  484
            +  L+ D++VYGKGAKRAVPDK VLL HLARK+ VL +S   MLDKLT H+Q  L  ++E
Sbjct  421  DISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNIE  480

Query  485  QPLANVLAKMEITGISVKKETLQDMEKANQAVIDELTQEIYDLAGMEFNINSPKQLGELL  544
             PLANVLAKMEI GI V++ TLQDM   N+ +I+ LTQEIYD+AG EFNINSPKQLG +L
Sbjct  481  LPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSIL  540

Query  545  FDKMQLPtsytkktktgystAVDVLERLAPISPIVSKILEYRQIAKLQSTYIVGLQDFIL  604
            F+KMQLP   TKKTKTGYSTAVDVLERLAPI+PIV+KIL+YRQI+KLQSTY++GLQD+IL
Sbjct  541  FEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYIL  600

Query  605  KDGKIHTRYLQDLTQTGRLSSVDPNLQNIPVRLEQGRLIRKAFVPETADEVLLSSDYSQI  664
             DGKIHTRY+QDLTQTGRLSSVDPNLQNIP+RLEQGRLIRKAF P   D VLLSSDYSQI
Sbjct  601  ADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQI  660

Query  665  ELRVLAHISNDEHLIAAFREGADIHTSTAMRVFGIEKPEDVTPNDRRNAKAVNFGIVYGI  724
            ELRVLAHIS DEHLIAAF EGADIHTSTAMRVFGI+K+ DVT+NDRRNAKAVNFGIVYGI
Sbjct  661  ELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGI  720

Query  725  SDYGLANNLGIPRKVAKQYIETYFERYPGIKDYMERVVRDSKAKGYVETLFHRRRELPDI  784
            SD+GL+NNLGI RK +K YI+TYFERYPGIK YME VVR++K KGYVETLF RRRELPDI
Sbjct  721  SDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDI  780

Query  785  NARNFNVRQFAERTAINSPIQGSAADILKIAMINLDKALVEGKFKTKMLLQVHDEIILEV  844
            N+RNFNVR FAERTAINSPIQGSAADILKIAMINLDKAL  G F++KMLLQVHDEI+LEV
Sbjct  781  NSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEV  840

Query  845  PKDELEAIEKLVKETMESAIELSVPLVADESAGQTWYEAK  884
            P+DEL AI KLVK+TME+A++L+VPL  DES+GQ+WYEAK
Sbjct  841  PNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

87) polA in NC_016826


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score = 1128 bits (4278),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 681/880 (78%), Positives = 780/880 (89%), Gaps = 2/880 (0%)

Query  1    MENKKKLLLIDGSSVAYRAFFALYNQIDRFKNRAGLHTNAIYGFHLMLNHLLERIQPTHV  60
            MENK+KLLLIDGSSVA+RAFFALYNQIDRFKN++GLHTNAIYGFHLML+H++ R++PTHV
Sbjct  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60

Query  61   LVAFDAGKTTFRTEMYKDYKAGRAKTPDEFREQLPYIREMLTALGIKWYELENYEADDII  120
            LVAFDAGKTTFRTEMY DYKAGRAKTPDEFREQ++YIREMLTALGI  YELE+YEADDII
Sbjct  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120

Query  121  GTLDKLAENED-EYDVTIVSGDKDLIQLADNNTTVEISKKGVAEFEEFTPAYLMEKMGIT  179
            GTLDK+AE  +  +DVTIVSGDKDLIQL+D+NT VEISKKGVAEFEEFTPAYLMEKMG+T
Sbjct  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180

Query  180  PKQFIDLKALMGDKSDNIPGVTKVGEKTGLKLLLEYGSLEGVYENIDGMKKSKMKENLIN  239
            P+QFIDLKALMGDKSDNIPGVTK+GEKTGLKLL E+GSLEG+YE+IDG K SKMKENLIN
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  240  DKEQAFLSKTLATINITAPIAIGLDDINYSRPDLEKLVPFYDEMGFKQFKDNLGATKKQE  299
            D++QAFLSKTLATIN ++PI+IGLDDI Y+ PD+  L  FYDEM+F Q+K  L++   QE
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQE  300

Query  300  KFDV-AYTEVDSLSADMFTDDQFFYFEILGDNYHVENIIGFAWGNDKAIYASTNldllkd  358
               V +Y EV ++SAD+F+ +++FYFE L DNYH E IIGFAWG++  IYAST+L LL  
Sbjct  301  PVAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLAT  360

Query  359  dlfkaalakPIKTYDFKRSKVLLSHLGIDLPAPAFDSRLAKYLLSTVDDNELSTIARLYT  418
            D FK  + KPI TYDFKRSKVLLSHLGI+L AP++D+RLA+YLLSTV+DNELSTIAR++T
Sbjct  361  DSFKQVFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIFT  420

Query  419  EYVLDSDEAVYGKGAKRAVPDKAVLLSHLARKIVVLNHSEKAMLDKLTEHQQASLLFDME  478
            +  L+ D++VYGKGAKRAVPDK VLL HLARK+ VL +S   MLDKLT H+Q  L  ++E
Sbjct  421  DISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNIE  480

Query  479  QPLANVLAKMEIAGISVKKETLQDMEKANQAVIDELTQEIYDLAGMEFNINSPKQLGELL  538
             PLANVLAKMEI GI V++ TLQDM   N+ +I+ LTQEIYD+AG EFNINSPKQLG +L
Sbjct  481  LPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSIL  540

Query  539  FDKMQLPtsytkktktgystAVDVLERLAPISPIVSKILEYRQIAKLQSTYIVGLQDFIL  598
            F+KMQLP   TKKTKTGYSTAVDVLERLAPI+PIV+KIL+YRQI+KLQSTY++GLQD+IL
Sbjct  541  FEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYIL  600

Query  599  KDGKIHTRYLQDLTQTGRLSSVDPNLQNIPVRLEQGRLIRKAFVPETADEVLLSSDYSQI  658
             DGKIHTRY+QDLTQTGRLSSVDPNLQNIP+RLEQGRLIRKAF P   D VLLSSDYSQI
Sbjct  601  ADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQI  660

Query  659  ELRVLAHISNDEHLIAAFRKGADIHTSTAMRVFGIEKAEDVTPNDRRNAKAVNFGIVYGI  718
            ELRVLAHIS DEHLIAAF  GADIHTSTAMRVFGI+KA DVT+NDRRNAKAVNFGIVYGI
Sbjct  661  ELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGI  720

Query  719  SDYGLANNLGIPRKVAKQYIETYFERYPGIKDYMERVVRDAKDKGYVETLFHRRRELPDI  778
            SD+GL+NNLGI RK +K YI+TYFERYPGIK YME VVR+AKDKGYVETLF RRRELPDI
Sbjct  721  SDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDI  780

Query  779  NARNFNVRQFAERTAINSPIQGSAADILKIAMINLDKALVDGRFKTKMLLQVHDEIILEV  838
            N+RNFNVR FAERTAINSPIQGSAADILKIAMINLDKAL  G F++KMLLQVHDEI+LEV
Sbjct  781  NSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEV  840

Query  839  PKDELEAIEKLVKETMESAIELSVPLVADESAGQTWYEAK  878
            P+DEL AI KLVK+TME+A++L+VPL  DES+GQ+WYEAK
Sbjct  841  PNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

88) polI in NC_015291


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score = 1119 bits (4245),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 645/879 (74%), Positives = 781/879 (89%), Gaps = 4/879 (0%)

Query  2    DKKKLLLIDGSSVAFRAFFALYQQLDRFKNANGLHTNAIYGFQLMLNHVLERVEPSHVLV  61
            +K+KLLLIDGSSVAFRAFFALY+Q+DRFKN +GLHTNAIYGF+LML+H++ RV P+HVLV
Sbjct  3    NKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLV  62

Query  62   AFDAGKTTFRTEMYADYKGGRAKTPDEFREQFPFIRELLDHLGIRHYELPQYEADDIIGT  121
            AFDAGKTTFRTEMYADYK+GRAKTPDEFREQF++IRE+L  LGI  YEL +YEADDIIGT
Sbjct  63   AFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGT  122

Query  122  LGRLAEKD--SFDVTIVSGDKDLIQLTDEHTVVEISKKGVAEFEAFTPDYLMEKMGLTPA  179
            L+++AE+   +FDVTIVSGDKDLIQLTDE+TVVEISKKGVAEFE FTP YLMEKMGLTP 
Sbjct  123  LDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPN  182

Query  180  QFIDLKALMGDKSDNIPGVTKVGEKTGIKLLLEHGSLEGIYENIDGMKASKMKENLINDK  239
            QFIDLKALMGDKSDNIPGVTK+GEKTG+KLL E GSLEGIYE+IDG K+SKMKENLIND+
Sbjct  183  QFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDR  242

Query  240  EQAFLSKTLATIETQAPIEIGLDDLVYNGPDVENLGKFYDEMGFKQLKQALNVS-SKDAP  298
            +QAFLSKTLATI+T +PI IGLDD+VYNGPDV +L++FYDEM+F QLK++L    ++++ 
Sbjct  243  DQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEPV  302

Query  299  ESLDFTIVDQVSQDMLSADSIFHFELFGENYHTDDLVGFAWSCGDKLYTTDKLELLQEPI  358
              + +  V +VS D++SA+ IF FE + +NYH + ++GFAW+ G+++Y++  L LL    
Sbjct  303  AVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLATDS  362

Query  359  LKEFLEKTPLKVYDFKKAKVLLNRLGLNLQAPAYDSRLAKYLLSTVENNEISTIANLYGQ  418
            +K+ ++K P+  YDFK++KVLL++LG++L AP+YD+RLA+YLLSTVE+NE+STIA ++ +
Sbjct  363  FKQVFQK-PIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIFTD  421

Query  419  TYLVDDETFYGKGVKKAIPEREKFLEHLARKVAVLVETEPVLLEKLSEHGQLDLLYDMEQ  478
              L +D+T YGKG K+A+P+++ +LEHLARKV VL+++ + +L+KL+ H QLDL  ++E 
Sbjct  422  ISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNIEL  481

Query  479  PLAFVLAKMEIAGIKVKKETLLEMQAENEVVIEQLTQEIYELAGEEFNINSPKQLGVLLF  538
            PLA VLAKMEI GIKV++ TL +M  +N V+IE LTQEIY++AG+EFNINSPKQLG +LF
Sbjct  482  PLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSILF  541

Query  539  EKLGLPLEYTKKTKTGYSTAVDVLERLAPIAPIVKKILDYRQIAKIQSTYVIGLQDWILD  598
            EK+ LPLE TKKTKTGYSTAVDVLERLAPIAPIV KILDYRQI+K+QSTYVIGLQD IL 
Sbjct  542  EKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYILA  601

Query  599  DGKIHTRYVQDLTQTGRLSSVDPNLQNIPVRLEQGRLIRKAFVPEWEDSVLLSSDYSQIE  658
            DGKIHTRYVQDLTQTGRLSSVDPNLQNIP+RLEQGRLIRKAF P  ED+VLLSSDYSQIE
Sbjct  602  DGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQIE  661

Query  659  LRVLAHISKDEHLIKAFQEGADIHTSTAMRVFGIERPEDVTPNDRRNAKAVNFGVVYGIS  718
            LRVLAHIS DEHLI AF+EGADIHTSTAMRVFGI+++ DVT+NDRRNAKAVNFG+VYGIS
Sbjct  662  LRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGIS  721

Query  719  DFGLSNNLGISRKEAKAYIDTYFERFPGIKNYMDEVVREARDKGYVETLFKRRRELPDIN  778
            DFGLSNNLGI+RK++K+YIDTYFER+PGIK YM++VVREA+DKGYVETLFKRRRELPDIN
Sbjct  722  DFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDIN  781

Query  779  SRNFNIRGFAERTAINSPIQGSAADILKIAMIQLDKALVEGGYQTKMLLQVHDEIVLEVP  838
            SRNFN+R+FAERTAINSPIQGSAADILKIAMI+LDKAL  GG+++KMLLQVHDEIVLEVP
Sbjct  782  SRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEVP  841

Query  839  KSELAAVKDLVKQTMEEAIQLSVPLIADENEGATWYEAK  877
            + EL+A+K LVK+TME A++L+VPL  DE+ G +WYEAK
Sbjct  842  NDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

89) polI in NC_013853


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score = 1109 bits (4205),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 636/879 (73%), Positives = 776/879 (89%), Gaps = 4/879 (0%)

Query  2    DKKKLLLIDGSSVAFRAFFALYQQLDRFKNAAGLHTNAIYGFQLMLSHLLERVEPSHILV  61
            +K+KLLLIDGSSVAFRAFFALY+Q+DRFKN +GLHTNAIYGF+LML H++ RV P+H+LV
Sbjct  3    NKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLV  62

Query  62   AFDAGKTTFRTEMYADYKGGRAKTPDEFREQFPFIRELLDHMGIRHYELAQYEADDIIGT  121
            AFDAGKTTFRTEMYADYK+GRAKTPDEFREQF++IRE+L  +GI  YEL +YEADDIIGT
Sbjct  63   AFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGT  122

Query  122  LDKLAEQDG--FDITIVSGDKDLIQLTDEHTVVEISKKGVAEFEAFTPEYLMEKLGITPT  179
            LDK+AE+    FD+TIVSGDKDLIQLTDE+TVVEISKKGVAEFE FTP YLMEK+G+TP 
Sbjct  123  LDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPN  182

Query  180  QFIDLKALMGDKSDNIPGVTKIGEKTGIKLLLEHGSLEGIYENIDGMKASKMKDNLINDK  239
            QFIDLKALMGDKSDNIPGVTKIGEKTG+KLL E GSLEGIYE+IDG K+SKMK+NLIND+
Sbjct  183  QFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDR  242

Query  240  EQAFLSKTLATIDTKAPIEIGLEDLVYSGPDVENLGKFYDEMGFKQLKQALNVS-SADVT  298
            +QAFLSKTLATI+T +PI IGL+D+VY+GPDV +L++FYDEM+F QLK++L    + +  
Sbjct  243  DQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEPV  302

Query  299  ESLDFTIVDQISQDMLSEESIFHFELFGENYHTDDLVGFAWSCGDKLYATDKLELLQEPI  358
              + +  V ++S D++S E IF FE + +NYH + ++GFAW+ G+++YA+  L LL    
Sbjct  303  AVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLATDS  362

Query  359  FKDFLEKTPLRVYDFKKAKVLLNRFGVDLQAPAFDSRLAKYLLSTVEDNEIATIASLYGQ  418
            FK+ ++K P+  YDFK++KVLL+++G++L AP++D+RLA+YLLSTVEDNE++TIA ++ +
Sbjct  363  FKQVFQK-PIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIFTD  421

Query  419  TYLVDDETFYGKGVKKAIPEREKFLEHLARKLAVLVETEPILLEKLSENGQLELLYDMEQ  478
              L +D+T YGKG K+A+P+++ +LEHLARK+ VL+++ + +L+KL+ + QL+L  ++E 
Sbjct  422  ISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNIEL  481

Query  479  PLAFVLAKMEIAGITVKKETLLEMQAENELVIEKLTQEIYELAGEEFNINSPKQLGVLLF  538
            PLA VLAKMEI GI V++ TL +M  +N ++IE LTQEIY++AG+EFNINSPKQLG +LF
Sbjct  482  PLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSILF  541

Query  539  EKLALPLEYTKKTKTGYSTAVDVLERLAPIAPIVKKILDYRQIAKIQSTYVIGLQDWILA  598
            EK+ LPLE TKKTKTGYSTAVDVLERLAPIAPIV KILDYRQI+K+QSTYVIGLQD ILA
Sbjct  542  EKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYILA  601

Query  599  DGKIHTRYVQDLTQTGRLSSVDPNLQNIPARLEQGRLIRKAFVPEWENSVLLSSDYSQIE  658
            DGKIHTRYVQDLTQTGRLSSVDPNLQNIP RLEQGRLIRKAF P  E++VLLSSDYSQIE
Sbjct  602  DGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQIE  661

Query  659  LRVLAHISKDEHLIKAFQEGADIHTSTAMRVFGIERPEDVTANDRRNAKAVNFGVVYGIS  718
            LRVLAHIS DEHLI AF+EGADIHTSTAMRVFGI+++ DVTANDRRNAKAVNFG+VYGIS
Sbjct  662  LRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGIS  721

Query  719  DFGLSNNLGISRKEAKAYIDTYFERFPGIKNYMDEVVREARDKGYVETLFKRRRELPDIN  778
            DFGLSNNLGI+RK++K+YIDTYFER+PGIK YM++VVREA+DKGYVETLFKRRRELPDIN
Sbjct  722  DFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDIN  781

Query  779  SRNFNIRGFAERTAINSPIQGSAADILKIAMIQLDKALVAGGYQTKMLLQVHDEIVLEVP  838
            SRNFN+R+FAERTAINSPIQGSAADILKIAMI+LDKAL AGG+++KMLLQVHDEIVLEVP
Sbjct  782  SRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEVP  841

Query  839  KSELAEMKKLVKQTMEEAIQLSVPLIADENEGATWYEAK  877
            + EL+ +KKLVK+TME A++L+VPL  DE+ G +WYEAK
Sbjct  842  NDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

90) SPPN_00560 in NC_015875


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score = 1105 bits (4188),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 635/879 (73%), Positives = 774/879 (89%), Gaps = 4/879 (0%)

Query  2    DKKKLLLIDGSSVAFRAFFALYQQLDRFKNAAGLHTNAIYGFQLMLSHLLERVEPSHILV  61
            +K+KLLLIDGSSVAFRAFFALY+Q+DRFKN +GLHTNAIYGF+LML H++ RV P+H+LV
Sbjct  3    NKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLV  62

Query  62   AFDAGKTTFRTEMYADYKGGRAKTPDEFREQFPFIRELLDHMGIRHYELAQYEADDIIGT  121
            AFDAGKTTFRTEMYADYK+GRAKTPDEFREQF++IRE+L  +GI  YEL +YEADDIIGT
Sbjct  63   AFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGT  122

Query  122  LDKLAEQDG--FDITIVSGDKDLIQLTDEHTVVEISKKGVAEFEAFTPDYLMEKMGITPT  179
            LDK+AE+    FD+TIVSGDKDLIQLTDE+TVVEISKKGVAEFE FTP YLMEKMG+TP 
Sbjct  123  LDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPN  182

Query  180  QFIDLKALMGDKSDNIPGVTKIGEKTGIKLLLEYGSLEGIYENIDGMKASKMKENLINDK  239
            QFIDLKALMGDKSDNIPGVTKIGEKTG+KLL E+GSLEGIYE+IDG K+SKMKENLIND+
Sbjct  183  QFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDR  242

Query  240  EQAFLSKTLATIDTKAPIAIGLEDLVYSGPDVENLGKFYDEMGFKQLKQALNVS-SADVS  298
            +QAFLSKTLATI+T +PI+IGL+D+VY+GPDV +L++FYDEM+F QLK++L    + +  
Sbjct  243  DQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEPV  302

Query  299  ESLDFTIVDQISQDMLSEESIFHFELFGENYHTDNLVGFAWSCGDKLYATDKIELLQDPI  358
              + +  V ++S D++S E IF FE + +NYH + ++GFAW+ G+++YA+  + LL    
Sbjct  303  AVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLATDS  362

Query  359  FKDFLEKTSLRVYDFKKVKVLLQRLGVDLQAPAFDIRLAKYLLSTVEDNEIATIASLYGQ  418
            FK+ ++K ++  YDFK+ KVLL +LG++L AP++D RLA+YLLSTVEDNE++TIA ++ +
Sbjct  363  FKQVFQK-PIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIFTD  421

Query  419  TYLVDDETFYGKGVKKAIPEREKFLEHLACKLAVLVETEPILLEKLSENGQLELLYEMEQ  478
              L +D+T YGKG K+A+P+++ +LEHLA K+ VL+++ + +L+KL+ + QL+L  ++E 
Sbjct  422  ISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNIEL  481

Query  479  PLAFVLAKMEIAGIRVKKETLCEMQAENELVIEKLTQEIYELAGEEFNINSPKQLGVLLF  538
            PLA VLAKMEI GI+V++ TL +M  +N ++IE LTQEIY++AG+EFNINSPKQLG +LF
Sbjct  482  PLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSILF  541

Query  539  EKLGLPLEYTKKTKTGYSTAVDVLERLAPIAPIVKKILDYRQIAKIQSTYVIGLQDWILD  598
            EK+ LPLE TKKTKTGYSTAVDVLERLAPIAPIV KILDYRQI+K+QSTYVIGLQD IL 
Sbjct  542  EKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYILA  601

Query  599  DGKIHTRYVQDLTQTGRLSSVDPNLQNIPARLEQGRLIRKAFVPEWEDSVLLSSDYSQIE  658
            DGKIHTRYVQDLTQTGRLSSVDPNLQNIP RLEQGRLIRKAF P  ED+VLLSSDYSQIE
Sbjct  602  DGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQIE  661

Query  659  LRVLAHISKDEHLIKAFQEGADIHTSTAMRVFGIERPEDVTANDRRNAKAVNFGVVYGIS  718
            LRVLAHIS DEHLI AF+EGADIHTSTAMRVFGI+++ DVTANDRRNAKAVNFG+VYGIS
Sbjct  662  LRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGIS  721

Query  719  DFGLSNNLGISRKEAKAYIDTYFERFPGIKNYMDEVVREARDKGYVETLFKRRRELPDIN  778
            DFGLSNNLGI+RK++K+YIDTYFER+PGIK YM++VVREA+DKGYVETLFKRRRELPDIN
Sbjct  722  DFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDIN  781

Query  779  SRNFNIRGFAERTAINSPIQGSAADILKIAMIQLDKALVAGAYQTKMLLQVHDEIVLEVP  838
            SRNFN+R+FAERTAINSPIQGSAADILKIAMI+LDKAL AG++++KMLLQVHDEIVLEVP
Sbjct  782  SRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEVP  841

Query  839  KSELAEMKKLVKQTMEEAIQLSVPLIADENEGATWYEAK  877
            + EL+ +KKLVK+TME A++L+VPL  DE+ G +WYEAK
Sbjct  842  NDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

91) polA in NC_011072


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score = 1104 bits (4187),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 636/879 (73%), Positives = 772/879 (88%), Gaps = 4/879 (0%)

Query  2    DKKKLLLIDGSSVAFRAFFALYQQLDRFKNAAGLHTNAIYGFQLMLSHLLERVEPSHILV  61
            +K+KLLLIDGSSVAFRAFFALY+Q+DRFKN +GLHTNAIYGF+LML H++ RV P+H+LV
Sbjct  3    NKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLV  62

Query  62   AFDAGKTTFRTEMYADYKGGRAKTPDEFREQFPFIRELLDHMGIRHYELAQYEADDIIGT  121
            AFDAGKTTFRTEMYADYK+GRAKTPDEFREQF++IRE+L  +GI  YEL +YEADDIIGT
Sbjct  63   AFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGT  122

Query  122  LDKLAEQDG--FDITIVSGDKDLIQLTDEHTVVEISKKGVAEFEAFTPDYLMEEMGLTPA  179
            LDK+AE+    FD+TIVSGDKDLIQLTDE+TVVEISKKGVAEFE FTP YLME MGLTP 
Sbjct  123  LDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPN  182

Query  180  QFIDLKALMGDKSDNIPGVTKVGEKTGIKLLLEYGSLEGIYENIDGMKTSKMKENLINDK  239
            QFIDLKALMGDKSDNIPGVTK+GEKTG+KLL E+GSLEGIYE+IDG KTSKMKENLIND+
Sbjct  183  QFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDR  242

Query  240  EQAFLSKTLATIDTKAPIAIGLEDLVYSGPDVENLGKFYDEMGFKQLKQALNVS-SADVS  298
            +QAFLSKTLATI+T +PI+IGL+D+VY+GPDV +L++FYDEM+F QLK++L    + +  
Sbjct  243  DQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEPV  302

Query  299  ESLDFTIVDQISQDMLSEESIFHFELFGENYHTDNLVGFAWSCGDKLYATDKLELLQDPI  358
              + +  V ++S D++S E IF FE + +NYH + ++GFAW+ G+++YA+  L LL    
Sbjct  303  AVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLATDS  362

Query  359  FKDFLEKTSLRVYDFKKVKVLLQRFGVDLQAPAFDIRLAKYLLSTVEDNEIATIASLYGQ  418
            FK+ ++K ++  YDFK+ KVLL ++G++L AP++D RLA+YLLSTVEDNE++TIA ++ +
Sbjct  363  FKQVFQK-PIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIFTD  421

Query  419  TYLVDDETFYGKGVKKAIPEREKFLEHLACKLAVLVETEPILLEKLSENGQLELLYDMEQ  478
              L +D+T YGKG K+A+P+++ +LEHLA K+ VL+++ + +L+KL+ + QL+L  ++E 
Sbjct  422  ISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNIEL  481

Query  479  PLAFVLAKMEIAGIMVKKETLLEMQAENELVIEKLTQEIYELAGEEFNVNSPKQLGVLLF  538
            PLA VLAKMEI GI V++ TL +M  +N ++IE LTQEIY++AG+EFN+NSPKQLG +LF
Sbjct  482  PLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSILF  541

Query  539  EKLGLPLEYTKKTKTGYSTAVDVLERLAPIAPIVKKILDYRQIAKIQSTYVIGLQDWILA  598
            EK+ LPLE TKKTKTGYSTAVDVLERLAPIAPIV KILDYRQI+K+QSTYVIGLQD ILA
Sbjct  542  EKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYILA  601

Query  599  DGKIHTRYVQDLTQTGRLSSVDPNLQNIPARLEQGRLIRKAFVPEWEDSVLLSSDYSQIE  658
            DGKIHTRYVQDLTQTGRLSSVDPNLQNIP RLEQGRLIRKAF P  ED+VLLSSDYSQIE
Sbjct  602  DGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQIE  661

Query  659  LRVLAHISKDEHLIKAFQEGADIHTSTAMRVFGIERPDDVTANDRRNAKAVNFGVVYGIS  718
            LRVLAHIS DEHLI AF+EGADIHTSTAMRVFGI+++ DVTANDRRNAKAVNFG+VYGIS
Sbjct  662  LRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGIS  721

Query  719  DFGLSNNLGISRKEAKAYIDTYFERFPGIKNYMDEVVREARDKGYVETLFKRRRELPDIN  778
            DFGLSNNLGI+RK++K+YIDTYFER+PGIK YM++VVREA+DKGYVETLFKRRRELPDIN
Sbjct  722  DFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDIN  781

Query  779  SRNFNIRGFAERTAINSPIQGSAADILKIAMIQLDKALVAGGYQTKMLLQVHDEIVLEVP  838
            SRNFN+R+FAERTAINSPIQGSAADILKIAMI+LDKAL AGG+++KMLLQVHDEIVLEVP
Sbjct  782  SRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEVP  841

Query  839  KSELVEMKKLVKQTMEEAIQLSVPLIADENEGATWYEAK  877
            + EL  +KKLVK+TME A++L+VPL  DE+ G +WYEAK
Sbjct  842  NDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

92) polA in NC_017594


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score = 1103 bits (4182),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 654/834 (79%), Positives = 753/834 (91%), Gaps = 1/834 (0%)

Query  1    MLDNLLERIQPTHVLVAFDAGKTTFRTEMFADYKAGRAKTPEEFREQFPYIREMLAARGI  60
            MLD+++ R++PTHVLVAFDAGKTTFRTEM+ADYKAGRAKTP+EFREQF+YIREML+A GI
Sbjct  47   MLDHMMKRVRPTHVLVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGI  106

Query  61   AYYDLAQYEADDIIGTLAKMAENTSEDYQITVVSGDKDLIQLTDENTVVEISKKGVAEFE  120
            AYY+L +YEADDIIGTL KMAE T   +++T+VSGDKDLIQLTDENTVVEISKKGVAEFE
Sbjct  107  AYYELEHYEADDIIGTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFE  166

Query  121  AFTPDYLMKKMGITPAQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLLEHGSLEGIYNHI  180
             FTP YLM KMG+TP QFIDLKALMGDKSDNIPGVTKIGEKTGLKLL E GSLEGIY+HI
Sbjct  167  EFTPAYLMEKMGLTPNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHI  226

Query  181  DEMKKSKMKENLINDKEQAFLSKTLATIDTQSPIEIGLDDTAFTGPDLEKLTAFYDEMGF  240
            D  K SKMKENLIND++QAFLSKTLATI+T SPI IGLDD  + GPD+  L+ FYDEM+F
Sbjct  227  DGFKTSKMKENLINDRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDF  286

Query  241  VQFKNALGGEAVPQDFDV-AYAEPSQVTEDHFSPDDFFYFEILGDNYHTEPIIGFAWGND  299
            VQ+K++L+++   +   V +Y E ++V+ D FS++D+FYFE L DNYH E+IIGFAWG++
Sbjct  287  VQLKKGLASQMPQEPVAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHG  346

Query  300  KQIYASTDTDLLKSEAFQAALSKAVNIYDFKRSKVLLSHLGIDLPTANFDARLAKYLLST  359
             QIYASTD  LL +++F+  + K++  YDFKRSKVLLSHLGI+L ++++DARLA+YLLST
Sbjct  347  EQIYASTDLSLLATDSFKQVFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLST  406

Query  360  VEDNELSTIARLYTDLPLETDEVVYGKGAKRAVPEKEVLLSHlakkvkvlqvakpvMLEK  419
            VEDNELSTIAR++TD++LE D+ VYGKGAKRAVP+K+VLL HLA+KVKVL  +K+ ML+K
Sbjct  407  VEDNELSTIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDK  466

Query  420  LAEHGQSELLFDMELPLANVLAKMEIAGIKVKGQTLNEMAVENQVVIDKLTQEIYEMAGE  479
            L+ H Q +L  ++ELPLANVLAKMEI GIKV+  TL++MA +N+V+I+ LTQEIY+MAG+
Sbjct  467  LTAHEQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQ  526

Query  480  EFNINSPKQLGVILFEKMGLPLEYTKKTKTGYSTAVDVLERLAPIAPIVAKILEYRQITK  539
            EFNINSPKQLG ILFEKM LPLE TKKTKTGYSTAVDVLERLAPIAPIVAKIL+YRQITK
Sbjct  527  EFNINSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITK  586

Query  540  LQSTYVLGLQDYILEDGKIHTRYVQDLTQTGRLSSVDPNLQNIPVRLEQGRLIRKAFVPS  599
            LQSTYV+GLQDYIL DGKIHTRYVQDLTQTGRLSSVDPNLQNIP+RLEQGRLIRKAF PS
Sbjct  587  LQSTYVIGLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPS  646

Query  600  TEDAVLLSSDYSQIELRVLAHISGDEHLIAAFKEGADIHTSTAMRVFGIEKPEDVTPNDR  659
             EDAVLLSSDYSQIELRVLAHISGDEHLIAAF+EGADIHTSTAMRVFGI+K+ DVT+NDR
Sbjct  647  HEDAVLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDR  706

Query  660  RNAKAVNFGIVYGISDFGLSNNLGISRKKAKEYIDTYFERYPGIKAYMDNVVREAKDKGY  719
            RNAKAVNFGIVYGISDFGLSNNLGI+RK++K YIDTYFERYPGIKAYM+NVVREAKDKGY
Sbjct  707  RNAKAVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGY  766

Query  720  VETLFHRRRELPDINSRNFNVRNFAERTAINSPIQGSAADILKIAMINLDKALVEGGYKT  779
            VETLF RRRELPDINSRNFNVR+FAERTAINSPIQGSAADILKIAMINLDKAL  GG+++
Sbjct  767  VETLFKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRA  826

Query  780  KMLLQVHDEIVLEVPNDELVAMKALVKETMEAAVELAVPLIADENDGRTWYEAK  833
            KMLLQVHDEIVLEVPNDEL A+K LVK+TMEAAV+LAVPL  DE+ G++WYEAK
Sbjct  827  KMLLQVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

93) SP70585_0092 in NC_012468


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score = 1102 bits (4180),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 636/879 (73%), Positives = 771/879 (88%), Gaps = 4/879 (0%)

Query  2    DKKKLLLIDGSSVAFRAFFALYQQLDRFKNAAGLHTNAIYGFQLMLSHLLERVEPSHILV  61
            +K+KLLLIDGSSVAFRAFFALY+Q+DRFKN +GLHTNAIYGF+LML H++ RV P+H+LV
Sbjct  3    NKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLV  62

Query  62   AFDAGKTTFRTEMYADYKGGRAKTPDEFREQFPFIRELLDHMGIRHYELAQYEADDIIGT  121
            AFDAGKTTFRTEMYADYK+GRAKTPDEFREQF++IRE+L  +GI  YEL +YEADDIIGT
Sbjct  63   AFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGT  122

Query  122  LDKLAEQDG--FDITIVSGDKDLIQLTDEHTVVEISKKGVAEFEAFTPDYLMEEMGLTPA  179
            LDK+AE+    FD+TIVSGDKDLIQLTDE+TVVEISKKGVAEFE FTP YLME MGLTP 
Sbjct  123  LDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPN  182

Query  180  QFIDLKALMGDKSDNIPGVTKVGEKTGIKLLLEHGSLEGIYENIDGMKTSKMKENLINDK  239
            QFIDLKALMGDKSDNIPGVTK+GEKTG+KLL E GSLEGIYE+IDG KTSKMKENLIND+
Sbjct  183  QFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDR  242

Query  240  EQAFLSKTLATIDTKAPIAIGLEDLVYSGPDVENLGKFYDEMGFKQLKQALNVS-SADVA  298
            +QAFLSKTLATI+T +PI+IGL+D+VY+GPDV +L++FYDEM+F QLK++L    + +  
Sbjct  243  DQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEPV  302

Query  299  EGLDFTIVDQISQDMLSEESIFHFELFGENYHTDNLVGFAWSCGDKLYATDKLELLQDPI  358
              + +  V ++S D++S E IF FE + +NYH + ++GFAW+ G+++YA+  L LL    
Sbjct  303  AVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLATDS  362

Query  359  FKDFLEKTSLRVYDFKKVKVLLQRFGVDLQAPAFDIRLAKYLLSTVEDNEIATIASLYGQ  418
            FK+ ++K ++  YDFK+ KVLL ++G++L AP++D RLA+YLLSTVEDNE++TIA ++ +
Sbjct  363  FKQVFQK-PIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIFTD  421

Query  419  TYLVDDETFYGKGVKKAIPEREKFLEHLACKLAVLVETEPILLEKLSENGQLELLYDMEQ  478
              L +D+T YGKG K+A+P+++ +LEHLA K+ VL+++ + +L+KL+ + QL+L  ++E 
Sbjct  422  ISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNIEL  481

Query  479  PLAFVLAKMEIAGIMVKKETLLEMQAENELVIEKLTQEIYELAGEEFNVNSPKQLGVLLF  538
            PLA VLAKMEI GI V++ TL +M  +N ++IE LTQEIY++AG+EFN+NSPKQLG +LF
Sbjct  482  PLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSILF  541

Query  539  EKLGLPLEYTKKTKTGYSTAVDVLERLAPIAPIVKKILDYRQIAKIQSTYVIGLQDWILA  598
            EK+ LPLE TKKTKTGYSTAVDVLERLAPIAPIV KILDYRQI+K+QSTYVIGLQD ILA
Sbjct  542  EKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYILA  601

Query  599  DGKIHTRYVQDLTQTGRLSSVDPNLQNIPARLEQGRLIRKAFVPEWEDSVLLSSDYSQIE  658
            DGKIHTRYVQDLTQTGRLSSVDPNLQNIP RLEQGRLIRKAF P  ED+VLLSSDYSQIE
Sbjct  602  DGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQIE  661

Query  659  LRVLAHISKDEHLIKAFQEGADIHTSTAMRVFGIERPDNVTANDRRNAKAVNFGVVYGIS  718
            LRVLAHIS DEHLI AF+EGADIHTSTAMRVFGI+++ +VTANDRRNAKAVNFG+VYGIS
Sbjct  662  LRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGIS  721

Query  719  DFGLSNNLGISRKEAKAYIDTYFERFPGIKNYMDEVVREARDKGYVETLFKRRRELPDIN  778
            DFGLSNNLGI+RK++K+YIDTYFER+PGIK YM++VVREA+DKGYVETLFKRRRELPDIN
Sbjct  722  DFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDIN  781

Query  779  SRNFNIRGFAERTAINSPIQGSAADILKIAMIQLDKALVAGGYQTKMLLQVHDEIVLEVP  838
            SRNFN+R+FAERTAINSPIQGSAADILKIAMI+LDKAL AGG+++KMLLQVHDEIVLEVP
Sbjct  782  SRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEVP  841

Query  839  KSELVEIKKLVKQTMEEAIQLSVPLIADENEGATWYEAK  877
            + EL  IKKLVK+TME A++L+VPL  DE+ G +WYEAK
Sbjct  842  NDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

94) polA in NC_011900


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score = 1101 bits (4174),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 634/879 (73%), Positives = 771/879 (88%), Gaps = 4/879 (0%)

Query  2    DKKKLLLIDGSSVAFRAFFALYQQLDRFKNAAGLHTNAIYGFQLMLSHLLERVEPSHILV  61
            +K+KLLLIDGSSVAFRAFFALY+Q+DRFKN +GLHTNAIYGF+LML H++ RV P+H+LV
Sbjct  3    NKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLV  62

Query  62   AFDAGKTTFRTEMYADYKGGRAKTPDEFREQFPFIRELLDHMGIRHYELAQYEADDIIGT  121
            AFDAGKTTFRTEMYADYK+GRAKTPDEFREQF++IRE+L  +GI  YEL +YEADDIIGT
Sbjct  63   AFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGT  122

Query  122  LDKLAEQDG--FDITIVSGDKDLIQLTDEHTVVEISKKGVAEFEAFTPDYLMEEMGLTPA  179
            LDK+AE+    FD+TIVSGDKDLIQLTDE+TVVEISKKGVAEFE FTP YLME MGLTP 
Sbjct  123  LDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPN  182

Query  180  QFIDLKALMGDKSDNIPGVTKVGEKTGIKLLLEHGSLEGIYENIDGMKTSKMKENLINDK  239
            QFIDLKALMGDKSDNIPGVTK+GEKTG+KLL E GSLEGIYE+IDG KTSKMKENLIND+
Sbjct  183  QFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDR  242

Query  240  EQAFLSKTLATIDTKAPIAIGLEDLVYSGPDVENLGKFYDEMGFKQLKQALNMS-SADVA  298
            +QAFLSKTLATI+T +PI+IGL+D+VY+GPDV +L++FYDEM+F QLK++L    + +  
Sbjct  243  DQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEPV  302

Query  299  EGLDFTIVDQISQDMLSEESIFHFELFGENYHTDNLVGFAWSCGDQLYATDKLELLQDPI  358
              + +  V ++S D++S E IF FE + +NYH + ++GFAW+ G+Q+YA+  L LL    
Sbjct  303  AVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLATDS  362

Query  359  FKDFLEKTSLRVYDFKKVKVLLQRFGVDLQAPAFDIRLAKYLLSTVEDNEIATIASLYGQ  418
            FK+ ++K ++  YDFK+ KVLL ++G++L AP++D RLA+YLLSTVEDNE++TIA ++ +
Sbjct  363  FKQVFQK-PIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIFTD  421

Query  419  TYLVDDETFYGKGVKKAIPEREKFLEHLACKLAVLVETEPILLEKLSENGQLELLYDMEQ  478
              L +D+T YGKG K+A+P+++ +LEHLA K+ VL+++ + +L+KL+ + QL+L  ++E 
Sbjct  422  ISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNIEL  481

Query  479  PLAFVLAKMEIAGIMVKKETLLEMQAENELVIEKLSQEIYELAGEEFNVNSPKQLGVLLF  538
            PLA VLAKMEI GI V++ TL +M  +N ++IE L+QEIY++AG+EFN+NSPKQLG +LF
Sbjct  482  PLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSILF  541

Query  539  EKLGLPLEYTKKTKTGYSTAVDVLERLAPIAPIVKKILDYRQIAKIQSTYVIGLQDWILA  598
            EK+ LPLE TKKTKTGYSTAVDVLERLAPIAPIV KILDYRQI+K+QSTYVIGLQD ILA
Sbjct  542  EKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYILA  601

Query  599  DGKIHTRYLQDLTQTGRLSSVDPNLQNIPARLEQGRLIRKAFVPEWEDSVLLSSDYSQIE  658
            DGKIHTRY+QDLTQTGRLSSVDPNLQNIP RLEQGRLIRKAF P  ED+VLLSSDYSQIE
Sbjct  602  DGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQIE  661

Query  659  LRVLAHISKDEHLIKAFQEGADIHTSTAMRVFGIERPDNVTANDRRNAKAVNFGVVYGIS  718
            LRVLAHIS DEHLI AF+EGADIHTSTAMRVFGI+++ +VTANDRRNAKAVNFG+VYGIS
Sbjct  662  LRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGIS  721

Query  719  DFGLSNNLGISRKEAKAYIDTYFERFPGIKNYMDEVVREARDKGYVETLFKRRRELPDIN  778
            DFGLSNNLGI+RK++K+YIDTYFER+PGIK YM++VVREA+DKGYVETLFKRRRELPDIN
Sbjct  722  DFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDIN  781

Query  779  SRNFNIRGFAERTAINSPIQGSAADILKIAMIQLDKALVAGGYQTKMLLQVHDEIVLEVP  838
            SRNFN+R+FAERTAINSPIQGSAADILKIAMI+LDKAL AGG+++KMLLQVHDEIVLEVP
Sbjct  782  SRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEVP  841

Query  839  KSELVEMKKLVKQTMEEAIQLSVPLIADENEGATWYEAK  877
            + EL  +KKLVK+TME A++L+VPL  DE+ G +WYEAK
Sbjct  842  NDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

95) SPD_0038 in NC_008533


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score = 1101 bits (4176),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 636/879 (73%), Positives = 771/879 (88%), Gaps = 4/879 (0%)

Query  2    DKKKLLLIDGSSVAFRAFFALYQQLDRFKNAAGLHTNAIYGFQLMLSHLLERVEPSHILV  61
            +K+KLLLIDGSSVAFRAFFALY+Q+DRFKN +GLHTNAIYGF+LML H++ RV P+H+LV
Sbjct  3    NKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLV  62

Query  62   AFDAGKTTFRTEMYADYKGGRAKTPDEFREQFPFIRELLDHMGIRHYELAQYEADDIIGT  121
            AFDAGKTTFRTEMYADYK+GRAKTPDEFREQF++IRE+L  +GI  YEL +YEADDIIGT
Sbjct  63   AFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGT  122

Query  122  LDKLAEQDG--FDITIVSGDKDLIQLTDEHTVVEISKKGVAEFEAFTPDYLMEEMGLTPA  179
            LDK+AE+    FD+TIVSGDKDLIQLTDE+TVVEISKKGVAEFE FTP YLME MGLTP 
Sbjct  123  LDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPN  182

Query  180  QFIDLKALMGDKSDNIPGVTKVGEKTGIKLLLEHGSLEGIYENIDGMKTSKMKENLINDK  239
            QFIDLKALMGDKSDNIPGVTK+GEKTG+KLL E GSLEGIYE+IDG KTSKMKENLIND+
Sbjct  183  QFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDR  242

Query  240  EQAFLSKTLATIDTKAPIAIGLEDLVYSGPDVENLGKFYDEMGFKQLKQALNMS-SADVA  298
            +QAFLSKTLATI+T +PI+IGL+D+VY+GPDV +L++FYDEM+F QLK++L    + +  
Sbjct  243  DQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEPV  302

Query  299  EGLDFTIVDQISQDMLSEESIFHFELFGENYHTDNLVGFAWSCGDQLYATDKLELLQDPI  358
              + +  V ++S D++S E IF FE + +NYH + ++GFAW+ G+Q+YA+  L LL    
Sbjct  303  AVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLATDS  362

Query  359  FKDFLEKTSLRVYDFKKVKVLLQRFGVDLQAPAFDIRLAKYLLSTVEDNEIATIASLYGQ  418
            FK+ ++K ++  YDFK+ KVLL ++G++L AP++D RLA+YLLSTVEDNE++TIA ++ +
Sbjct  363  FKQVFQK-PIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIFTD  421

Query  419  TYLVDDETFYGKGVKKAIPEREKFLEHLACKLAVLVETEPILLEKLSENGQLELLYDMEQ  478
              L +D+T YGKG K+A+P+++ +LEHLA K+ VL+++ + +L+KL+ + QL+L  ++E 
Sbjct  422  ISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNIEL  481

Query  479  PLAFVLAKMEIAGIVVKKETLLEMQAENELVIEKLTQEIYELAGEEFNVNSPKQLGVLLF  538
            PLA VLAKMEI GI V++ TL +M  +N ++IE LTQEIY++AG+EFN+NSPKQLG +LF
Sbjct  482  PLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSILF  541

Query  539  EKLGLPLEYTKKTKTGYSTAVDVLERLAPIAPIVKKILDYRQIAKIQSTYVIGLQDWILA  598
            EK+ LPLE TKKTKTGYSTAVDVLERLAPIAPIV KILDYRQI+K+QSTYVIGLQD ILA
Sbjct  542  EKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYILA  601

Query  599  DGKIHTRYVQDLTQTGRLSSVDPNLQNIPARLEQGRLIRKAFVPEWEDSVLLSSDYSQIE  658
            DGKIHTRYVQDLTQTGRLSSVDPNLQNIP RLEQGRLIRKAF P  ED+VLLSSDYSQIE
Sbjct  602  DGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQIE  661

Query  659  LRVLAHISKDEHLIKAFQEGADIHTSTAMRVFGIERPDNVTANDRRNAKAVNFGVVYGIS  718
            LRVLAHIS DEHLI AF+EGADIHTSTAMRVFGI+++ +VTANDRRNAKAVNFG+VYGIS
Sbjct  662  LRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGIS  721

Query  719  DFGLSNNLGISRKEAKAYIDTYFERFPGIKNYMDEVVREARDKGYVETLFKRRRELPDIN  778
            DFGLSNNLGI+RK++K+YIDTYFER+PGIK YM++VVREA+DKGYVETLFKRRRELPDIN
Sbjct  722  DFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDIN  781

Query  779  SRNFNIRGFAERTAINSPIQGSAADILKIAMIQLDKALVAGGYQTKMLLQVHDEIVLEVP  838
            SRNFN+R+FAERTAINSPIQGSAADILKIAMI+LDKAL AGG+++KMLLQVHDEIVLEVP
Sbjct  782  SRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEVP  841

Query  839  KSELVEMKKLVKQTMEEAIQLSVPLIADENEGATWYEAK  877
            + EL  +KKLVK+TME A++L+VPL  DE+ G +WYEAK
Sbjct  842  NDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

96) polA in NC_003098


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score = 1101 bits (4176),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 636/879 (73%), Positives = 771/879 (88%), Gaps = 4/879 (0%)

Query  2    DKKKLLLIDGSSVAFRAFFALYQQLDRFKNAAGLHTNAIYGFQLMLSHLLERVEPSHILV  61
            +K+KLLLIDGSSVAFRAFFALY+Q+DRFKN +GLHTNAIYGF+LML H++ RV P+H+LV
Sbjct  3    NKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLV  62

Query  62   AFDAGKTTFRTEMYADYKGGRAKTPDEFREQFPFIRELLDHMGIRHYELAQYEADDIIGT  121
            AFDAGKTTFRTEMYADYK+GRAKTPDEFREQF++IRE+L  +GI  YEL +YEADDIIGT
Sbjct  63   AFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGT  122

Query  122  LDKLAEQDG--FDITIVSGDKDLIQLTDEHTVVEISKKGVAEFEAFTPDYLMEEMGLTPA  179
            LDK+AE+    FD+TIVSGDKDLIQLTDE+TVVEISKKGVAEFE FTP YLME MGLTP 
Sbjct  123  LDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPN  182

Query  180  QFIDLKALMGDKSDNIPGVTKVGEKTGIKLLLEHGSLEGIYENIDGMKTSKMKENLINDK  239
            QFIDLKALMGDKSDNIPGVTK+GEKTG+KLL E GSLEGIYE+IDG KTSKMKENLIND+
Sbjct  183  QFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDR  242

Query  240  EQAFLSKTLATIDTKAPIAIGLEDLVYSGPDVENLGKFYDEMGFKQLKQALNMS-SADVA  298
            +QAFLSKTLATI+T +PI+IGL+D+VY+GPDV +L++FYDEM+F QLK++L    + +  
Sbjct  243  DQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEPV  302

Query  299  EGLDFTIVDQISQDMLSEESIFHFELFGENYHTDNLVGFAWSCGDQLYATDKLELLQDPI  358
              + +  V ++S D++S E IF FE + +NYH + ++GFAW+ G+Q+YA+  L LL    
Sbjct  303  AVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLATDS  362

Query  359  FKDFLEKTSLRVYDFKKVKVLLQRFGVDLQAPAFDIRLAKYLLSTVEDNEIATIASLYGQ  418
            FK+ ++K ++  YDFK+ KVLL ++G++L AP++D RLA+YLLSTVEDNE++TIA ++ +
Sbjct  363  FKQVFQK-PIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIFTD  421

Query  419  TYLVDDETFYGKGVKKAIPEREKFLEHLACKLAVLVETEPILLEKLSENGQLELLYDMEQ  478
              L +D+T YGKG K+A+P+++ +LEHLA K+ VL+++ + +L+KL+ + QL+L  ++E 
Sbjct  422  ISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNIEL  481

Query  479  PLAFVLAKMEIAGIVVKKETLLEMQAENELVIEKLTQEIYELAGEEFNVNSPKQLGVLLF  538
            PLA VLAKMEI GI V++ TL +M  +N ++IE LTQEIY++AG+EFN+NSPKQLG +LF
Sbjct  482  PLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSILF  541

Query  539  EKLGLPLEYTKKTKTGYSTAVDVLERLAPIAPIVKKILDYRQIAKIQSTYVIGLQDWILA  598
            EK+ LPLE TKKTKTGYSTAVDVLERLAPIAPIV KILDYRQI+K+QSTYVIGLQD ILA
Sbjct  542  EKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYILA  601

Query  599  DGKIHTRYVQDLTQTGRLSSVDPNLQNIPARLEQGRLIRKAFVPEWEDSVLLSSDYSQIE  658
            DGKIHTRYVQDLTQTGRLSSVDPNLQNIP RLEQGRLIRKAF P  ED+VLLSSDYSQIE
Sbjct  602  DGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQIE  661

Query  659  LRVLAHISKDEHLIKAFQEGADIHTSTAMRVFGIERPDNVTANDRRNAKAVNFGVVYGIS  718
            LRVLAHIS DEHLI AF+EGADIHTSTAMRVFGI+++ +VTANDRRNAKAVNFG+VYGIS
Sbjct  662  LRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGIS  721

Query  719  DFGLSNNLGISRKEAKAYIDTYFERFPGIKNYMDEVVREARDKGYVETLFKRRRELPDIN  778
            DFGLSNNLGI+RK++K+YIDTYFER+PGIK YM++VVREA+DKGYVETLFKRRRELPDIN
Sbjct  722  DFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDIN  781

Query  779  SRNFNIRGFAERTAINSPIQGSAADILKIAMIQLDKALVAGGYQTKMLLQVHDEIVLEVP  838
            SRNFN+R+FAERTAINSPIQGSAADILKIAMI+LDKAL AGG+++KMLLQVHDEIVLEVP
Sbjct  782  SRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEVP  841

Query  839  KSELVEMKKLVKQTMEEAIQLSVPLIADENEGATWYEAK  877
            + EL  +KKLVK+TME A++L+VPL  DE+ G +WYEAK
Sbjct  842  NDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

97) polA in NC_018594


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score = 1101 bits (4174),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 635/879 (73%), Positives = 771/879 (88%), Gaps = 4/879 (0%)

Query  2    DKKKLLLIDGSSVAFRAFFALYQQLDRFKNAAGLHTNAIYGFQLMLSHLLERVEPSHILV  61
            +K+KLLLIDGSSVAFRAFFALY+Q+DRFKN +GLHTNAIYGF+LML H++ RV P+H+LV
Sbjct  3    NKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLV  62

Query  62   AFDAGKTTFRTEMYADYKGGRAKTPDEFREQFPFIRELLDHMGIRHYELAQYEADDIIGT  121
            AFDAGKTTFRTEMYADYK+GRAKTPDEFREQF++IRE+L  +GI  YEL +YEADDIIGT
Sbjct  63   AFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGT  122

Query  122  LDKLAEQDG--FDITIVSGDKDLIQLTDEHTVVEISKKGVAEFEAFTPDYLMEEMGLTPA  179
            LDK+AE+    FD+TIVSGDKDLIQLTDE+TVVEISKKGVAEFE FTP YLME MGLTP 
Sbjct  123  LDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPN  182

Query  180  QFIDLKALMGDKSDNIPGVTKVGEKTGIKLLLEHGSLEGIYENIDGMKTSKMKENLINDK  239
            QFIDLKALMGDKSDNIPGVTK+GEKTG+KLL E GSLEGIYE+IDG KTSKMKENLIND+
Sbjct  183  QFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDR  242

Query  240  EQAFLSKTLATIDTKAPIAIGLEDLVYSGPDVENLGKFYDEMGFKQLKQALNVS-SADVA  298
            +QAFLSKTLATI+T +PI+IGL+D+VY+GPDV +L++FYDEM+F QLK++L    + +  
Sbjct  243  DQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEPV  302

Query  299  KGLDFTIVDQISQDMLSEESIFHFELFGENYHTDNLVGFAWSCGDKLYATDKLELLQDPI  358
              + +  V ++S D++S E IF FE + +NYH + ++GFAW+ G+++YA+  L LL    
Sbjct  303  AVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLATDS  362

Query  359  FKDFLEKTSLRVYDFKKVKVLLQRFGVDLQAPAFDIRLAKYLLSTVEDNEIATIASLYGQ  418
            FK+ ++K ++  YDFK+ KVLL ++G++L AP++D RLA+YLLSTVEDNE++TIA ++ +
Sbjct  363  FKQVFQK-PIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIFTD  421

Query  419  TYLVDDETFYGKGVKKAIPEREKFLEHLACKLAVLVETEPILLEKLSENGQLELLYDMEQ  478
              L +D+T YGKG K+A+P+++ +LEHLA K+ VL+++ + +L+KL+ + QL+L  ++E 
Sbjct  422  ISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNIEL  481

Query  479  PLAFVLAKMEIAGIMVKKETLLEMQAENELVIEKLTQEIYELAGEEFNVNSPKQLGVLLF  538
            PLA VLAKMEI GI V++ TL +M  +N ++IE LTQEIY++AG+EFN+NSPKQLG +LF
Sbjct  482  PLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSILF  541

Query  539  EKLGLPLEYTKKTKTGYSTAVDVLERLAPIAPIVKKILDYRQIAKIQSTYVIGLQDWILA  598
            EK+ LPLE TKKTKTGYSTAVDVLERLAPIAPIV KILDYRQI+K+QSTYVIGLQD ILA
Sbjct  542  EKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYILA  601

Query  599  DGKIHTRYVQDLTQTGRLSSVDPNLQNIPARLEQGRLIRKAFVPEWEDSVLLSSDYSQIE  658
            DGKIHTRYVQDLTQTGRLSSVDPNLQNIP RLEQGRLIRKAF P  ED+VLLSSDYSQIE
Sbjct  602  DGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQIE  661

Query  659  LRVLAHISKDEHLIKAFQEGADIHTSTAMRVFGIERPDNVTANDRRNAKAVNFGVVYGIS  718
            LRVLAHIS DEHLI AF+EGADIHTSTAMRVFGI+++ +VTANDRRNAKAVNFG+VYGIS
Sbjct  662  LRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGIS  721

Query  719  DFGLSNNLGISRKEAKAYIDTYFERFPGIKNYMDEVVREARDKGYVETLFKRRRELPDIN  778
            DFGLSNNLGI+RK++K+YIDTYFER+PGIK YM++VVREA+DKGYVETLFKRRRELPDIN
Sbjct  722  DFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDIN  781

Query  779  SRNFNIRGFAERTAINSPIQGSAADILKIAMIQLDKALVAGGYQTKMLLQVHDEIVLEVP  838
            SRNFN+R+FAERTAINSPIQGSAADILKIAMI+LDKAL AGG+++KMLLQVHDEIVLEVP
Sbjct  782  SRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEVP  841

Query  839  KSELVEMKKLVKQTMEEAIQLSVPLIADENEGATWYEAK  877
            + EL  +KKLVK+TME A++L+VPL  DE+ G +WYEAK
Sbjct  842  NDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

98) MYY_0106 in NC_017769


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score = 1101 bits (4176),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 636/879 (73%), Positives = 771/879 (88%), Gaps = 4/879 (0%)

Query  2    DKKKLLLIDGSSVAFRAFFALYQQLDRFKNAAGLHTNAIYGFQLMLSHLLERVEPSHILV  61
            +K+KLLLIDGSSVAFRAFFALY+Q+DRFKN +GLHTNAIYGF+LML H++ RV P+H+LV
Sbjct  3    NKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLV  62

Query  62   AFDAGKTTFRTEMYADYKGGRAKTPDEFREQFPFIRELLDHMGIRHYELAQYEADDIIGT  121
            AFDAGKTTFRTEMYADYK+GRAKTPDEFREQF++IRE+L  +GI  YEL +YEADDIIGT
Sbjct  63   AFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGT  122

Query  122  LDKLAEQDG--FDITIVSGDKDLIQLTDEHTVVEISKKGVAEFEAFTPDYLMEEMGLTPA  179
            LDK+AE+    FD+TIVSGDKDLIQLTDE+TVVEISKKGVAEFE FTP YLME MGLTP 
Sbjct  123  LDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPN  182

Query  180  QFIDLKALMGDKSDNIPGVTKVGEKTGIKLLLEHGSLEGIYENIDGMKTSKMKENLINDK  239
            QFIDLKALMGDKSDNIPGVTK+GEKTG+KLL E GSLEGIYE+IDG KTSKMKENLIND+
Sbjct  183  QFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDR  242

Query  240  EQAFLSKTLATIDTKAPIAIGLEDLVYSGPDVENLGKFYDEMGFKQLKQALNVS-SADVS  298
            +QAFLSKTLATI+T +PI+IGL+D+VY+GPDV +L++FYDEM+F QLK++L    + +  
Sbjct  243  DQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEPV  302

Query  299  ESLDFTIVDQISQDMLSEESIFHFELFGENYHTDNLVGFAWSCGDKLYATDKLELLQDPI  358
              + +  V ++S D++S E IF FE + +NYH + ++GFAW+ G+++YA+  L LL    
Sbjct  303  AVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLATDS  362

Query  359  FKDFLEKTSLRVYDFKKVKVLLQRFGVDLQAPAFDIRLAKYLLSTVEDNEIATIASLYGQ  418
            FK+ ++K ++  YDFK+ KVLL ++G++L AP++D RLA+YLLSTVEDNE++TIA ++ +
Sbjct  363  FKQVFQK-PIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIFTD  421

Query  419  TYLVDDETFYGKGVKKAIPEREKFLEHLACKLAVLVETEPILLEKLSENGQLELLYDMEQ  478
              L +D+T YGKG K+A+P+++ +LEHLA K+ VL+++ + +L+KL+ + QL+L  ++E 
Sbjct  422  ISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNIEL  481

Query  479  PLAFVLAKMEIAGIMVKKETLLEMQAENELVIEKLTQEIYELAGEEFNVNSPKQLGVLLF  538
            PLA VLAKMEI GI V++ TL +M  +N ++IE LTQEIY++AG+EFN+NSPKQLG +LF
Sbjct  482  PLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSILF  541

Query  539  EKLGLPLEYTKKTKTGYSTAVDVLERLAPIAPIVKKILDYRQIAKIQSTYVIGLQDWILA  598
            EK+ LPLE TKKTKTGYSTAVDVLERLAPIAPIV KILDYRQI+K+QSTYVIGLQD ILA
Sbjct  542  EKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYILA  601

Query  599  DGKIHTRYVQDLTQTGRLSSVDPNLQNIPARLEQGRLIRKAFVPEWEDSVLLSSDYSQIE  658
            DGKIHTRYVQDLTQTGRLSSVDPNLQNIP RLEQGRLIRKAF P  ED+VLLSSDYSQIE
Sbjct  602  DGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQIE  661

Query  659  LRVLAHISKDEHLIKAFQEGADIHTSTAMRVFGIERPDDVTANDRRNAKAVNFGVVYGIS  718
            LRVLAHIS DEHLI AF+EGADIHTSTAMRVFGI+++ DVTANDRRNAKAVNFG+VYGIS
Sbjct  662  LRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGIS  721

Query  719  DFGLSNNLGISRKEAKAYIDTYFERFPGIKNYMDEVVREARDKGYVETLFKRRRELPDIN  778
            DFGLSNNLGI+RK++K+YIDTYFER+PGIK YM++VVREA+DKGYVETLFKRRRELPDIN
Sbjct  722  DFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDIN  781

Query  779  SRNFNIRGFAERTAINSPIQGSAADILKIAMIQLDKALVAGGYQTKMLLQVHDEIVLEVP  838
            SRNFN+R+FAERTAINSPIQGSAADILKIAMI+LDKAL AGG+++KMLLQVHDEIVLEVP
Sbjct  782  SRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEVP  841

Query  839  KSELVEMKKLVKQTMEEAIQLSVPLIADENEGATWYEAK  877
            + EL  +KKLVK+TME A++L+VPL  DE+ G +WYEAK
Sbjct  842  NDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

99) SPT_0070 in NC_012469


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score = 1101 bits (4176),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 636/879 (73%), Positives = 771/879 (88%), Gaps = 4/879 (0%)

Query  2    DKKKLLLIDGSSVAFRAFFALYQQLDRFKNAAGLHTNAIYGFQLMLSHLLERVEPSHILV  61
            +K+KLLLIDGSSVAFRAFFALY+Q+DRFKN +GLHTNAIYGF+LML H++ RV P+H+LV
Sbjct  3    NKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLV  62

Query  62   AFDAGKTTFRTEMYADYKGGRAKTPDEFREQFPFIRELLDHMGIRHYELAQYEADDIIGT  121
            AFDAGKTTFRTEMYADYK+GRAKTPDEFREQF++IRE+L  +GI  YEL +YEADDIIGT
Sbjct  63   AFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGT  122

Query  122  LDKLAEQDG--FDITIVSGDKDLIQLTDEHTVVEISKKGVAEFEAFTPDYLMEEMGLTPA  179
            LDK+AE+    FD+TIVSGDKDLIQLTDE+TVVEISKKGVAEFE FTP YLME MGLTP 
Sbjct  123  LDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPN  182

Query  180  QFIDLKALMGDKSDNIPGVTKVGEKTGIKLLLEHGSLEGIYENIDGMKTSKMKENLINDK  239
            QFIDLKALMGDKSDNIPGVTK+GEKTG+KLL E GSLEGIYE+IDG KTSKMKENLIND+
Sbjct  183  QFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDR  242

Query  240  EQAFLSKTLATIDTKAPIAIGLEDLVYSGPDVENLGKFYDEMGFKQLKQALNVS-SADVS  298
            +QAFLSKTLATI+T +PI+IGL+D+VY+GPDV +L++FYDEM+F QLK++L    + +  
Sbjct  243  DQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEPV  302

Query  299  ESLDFTIVDQISQDMLSEESIFHFELFGENYHTDNLVGFAWSCGDKLYATDKLELLQDPI  358
              + +  V ++S D++S E IF FE + +NYH + ++GFAW+ G+++YA+  L LL    
Sbjct  303  AVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLATDS  362

Query  359  FKDFLEKTSLRVYDFKKVKVLLQRFGVDLQAPAFDIRLAKYLLSTVEDNEIATIASLYGQ  418
            FK+ ++K ++  YDFK+ KVLL ++G++L AP++D RLA+YLLSTVEDNE++TIA ++ +
Sbjct  363  FKQVFQK-PIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIFTD  421

Query  419  TYLVDDETFYGKGVKKAIPEREKFLEHLACKLAVLVETEPILLEKLSENGQLELLYDMEQ  478
              L +D+T YGKG K+A+P+++ +LEHLA K+ VL+++ + +L+KL+ + QL+L  ++E 
Sbjct  422  ISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNIEL  481

Query  479  PLAFVLAKMEIAGIMVKKETLLEMQAENELVIEKLTQEIYELAGEEFNVNSPKQLGVLLF  538
            PLA VLAKMEI GI V++ TL +M  +N ++IE LTQEIY++AG+EFN+NSPKQLG +LF
Sbjct  482  PLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSILF  541

Query  539  EKLGLPLEYTKKTKTGYSTAVDVLERLAPIAPIVKKILDYRQIAKIQSTYVIGLQDWILA  598
            EK+ LPLE TKKTKTGYSTAVDVLERLAPIAPIV KILDYRQI+K+QSTYVIGLQD ILA
Sbjct  542  EKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYILA  601

Query  599  DGKIHTRYVQDLTQTGRLSSVDPNLQNIPARLEQGRLIRKAFVPEWEDSVLLSSDYSQIE  658
            DGKIHTRYVQDLTQTGRLSSVDPNLQNIP RLEQGRLIRKAF P  ED+VLLSSDYSQIE
Sbjct  602  DGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQIE  661

Query  659  LRVLAHISKDEHLIKAFQEGADIHTSTAMRVFGIERPDDVTANDRRNAKAVNFGVVYGIS  718
            LRVLAHIS DEHLI AF+EGADIHTSTAMRVFGI+++ DVTANDRRNAKAVNFG+VYGIS
Sbjct  662  LRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGIS  721

Query  719  DFGLSNNLGISRKEAKAYIDTYFERFPGIKNYMDEVVREARDKGYVETLFKRRRELPDIN  778
            DFGLSNNLGI+RK++K+YIDTYFER+PGIK YM++VVREA+DKGYVETLFKRRRELPDIN
Sbjct  722  DFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDIN  781

Query  779  SRNFNIRGFAERTAINSPIQGSAADILKIAMIQLDKALVAGGYQTKMLLQVHDEIVLEVP  838
            SRNFN+R+FAERTAINSPIQGSAADILKIAMI+LDKAL AGG+++KMLLQVHDEIVLEVP
Sbjct  782  SRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEVP  841

Query  839  KSELVEMKKLVKQTMEEAIQLSVPLIADENEGATWYEAK  877
            + EL  +KKLVK+TME A++L+VPL  DE+ G +WYEAK
Sbjct  842  NDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

100) polA in NC_014251


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score = 1101 bits (4176),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 636/879 (73%), Positives = 771/879 (88%), Gaps = 4/879 (0%)

Query  2    DKKKLLLIDGSSVAFRAFFALYQQLDRFKNAAGLHTNAIYGFQLMLSHLLERVEPSHILV  61
            +K+KLLLIDGSSVAFRAFFALY+Q+DRFKN +GLHTNAIYGF+LML H++ RV P+H+LV
Sbjct  3    NKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLV  62

Query  62   AFDAGKTTFRTEMYADYKGGRAKTPDEFREQFPFIRELLDHMGIRHYELAQYEADDIIGT  121
            AFDAGKTTFRTEMYADYK+GRAKTPDEFREQF++IRE+L  +GI  YEL +YEADDIIGT
Sbjct  63   AFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGT  122

Query  122  LDKLAEQDG--FDITIVSGDKDLIQLTDEHTVVEISKKGVAEFEAFTPDYLMEEMGLTPA  179
            LDK+AE+    FD+TIVSGDKDLIQLTDE+TVVEISKKGVAEFE FTP YLME MGLTP 
Sbjct  123  LDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPN  182

Query  180  QFIDLKALMGDKSDNIPGVTKVGEKTGIKLLLEHGSLEGIYENIDGMKTSKMKENLINDK  239
            QFIDLKALMGDKSDNIPGVTK+GEKTG+KLL E GSLEGIYE+IDG KTSKMKENLIND+
Sbjct  183  QFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDR  242

Query  240  EQAFLSKTLATIDTKAPIAIGLEDLVYSGPDVENLGKFYDEMGFKQLKQALNVS-SADVS  298
            +QAFLSKTLATI+T +PI+IGL+D+VY+GPDV +L++FYDEM+F QLK++L    + +  
Sbjct  243  DQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEPV  302

Query  299  ESLDFTIVDQISQDMLSEESIFHFELFGENYHTDNLVGFAWSCGDKLYATDKLELLQDPI  358
              + +  V ++S D++S E IF FE + +NYH + ++GFAW+ G+++YA+  L LL    
Sbjct  303  AVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLATDS  362

Query  359  FKDFLEKTSLRVYDFKKVKVLLQRFGVDLQAPAFDIRLAKYLLSTVEDNEIATIASLYGQ  418
            FK+ ++K ++  YDFK+ KVLL ++G++L AP++D RLA+YLLSTVEDNE++TIA ++ +
Sbjct  363  FKQVFQK-PIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIFTD  421

Query  419  TYLVDDETFYGKGVKKAIPEREKFLEHLACKLAVLVETEPILLEKLSENGQLELLYDMEQ  478
              L +D+T YGKG K+A+P+++ +LEHLA K+ VL+++ + +L+KL+ + QL+L  ++E 
Sbjct  422  ISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNIEL  481

Query  479  PLAFVLAKMEIAGIMVKKETLLEMQAENELVIEKLTQEIYELAGEEFNVNSPKQLGVLLF  538
            PLA VLAKMEI GI V++ TL +M  +N ++IE LTQEIY++AG+EFN+NSPKQLG +LF
Sbjct  482  PLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSILF  541

Query  539  EKLGLPLEYTKKTKTGYSTAVDVLERLAPIAPIVKKILDYRQIAKIQSTYVIGLQDWILA  598
            EK+ LPLE TKKTKTGYSTAVDVLERLAPIAPIV KILDYRQI+K+QSTYVIGLQD ILA
Sbjct  542  EKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYILA  601

Query  599  DGKIHTRYVQDLTQTGRLSSVDPNLQNIPARLEQGRLIRKAFVPEWEDSVLLSSDYSQIE  658
            DGKIHTRYVQDLTQTGRLSSVDPNLQNIP RLEQGRLIRKAF P  ED+VLLSSDYSQIE
Sbjct  602  DGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQIE  661

Query  659  LRVLAHISKDEHLIKAFQEGADIHTSTAMRVFGIERPDDVTANDRRNAKAVNFGVVYGIS  718
            LRVLAHIS DEHLI AF+EGADIHTSTAMRVFGI+++ DVTANDRRNAKAVNFG+VYGIS
Sbjct  662  LRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGIS  721

Query  719  DFGLSNNLGISRKEAKAYIDTYFERFPGIKNYMDEVVREARDKGYVETLFKRRRELPDIN  778
            DFGLSNNLGI+RK++K+YIDTYFER+PGIK YM++VVREA+DKGYVETLFKRRRELPDIN
Sbjct  722  DFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDIN  781

Query  779  SRNFNIRGFAERTAINSPIQGSAADILKIAMIQLDKALVAGGYQTKMLLQVHDEIVLEVP  838
            SRNFN+R+FAERTAINSPIQGSAADILKIAMI+LDKAL AGG+++KMLLQVHDEIVLEVP
Sbjct  782  SRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEVP  841

Query  839  KSELVEMKKLVKQTMEEAIQLSVPLIADENEGATWYEAK  877
            + EL  +KKLVK+TME A++L+VPL  DE+ G +WYEAK
Sbjct  842  NDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

101) SPAP_0083 in NC_014494


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score = 1100 bits (4171),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 636/879 (73%), Positives = 771/879 (88%), Gaps = 4/879 (0%)

Query  14   DKKKLLLIDGSSVAFRAFFALYQQLDRFKNAAGLHTNAIYGFQLMLSHLLERVEPSHILV  73
            +K+KLLLIDGSSVAFRAFFALY+Q+DRFKN +GLHTNAIYGF+LML H++ RV P+H+LV
Sbjct  3    NKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLV  62

Query  74   AFDAGKTTFRTEMYADYKGGRAKTPDEFREQFPFIRELLDHMGIRHYELAQYEADDIIGT  133
            AFDAGKTTFRTEMYADYK+GRAKTPDEFREQF++IRE+L  +GI  YEL +YEADDIIGT
Sbjct  63   AFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGT  122

Query  134  LDKLAEQDG--FDITIVSGDKDLIQLTDEHTVVEISKKGVAEFEAFTPDYLMEEMGLTPA  191
            LDK+AE+    FD+TIVSGDKDLIQLTDE+TVVEISKKGVAEFE FTP YLME MGLTP 
Sbjct  123  LDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPN  182

Query  192  QFIDLKALMGDKSDNIPGVTKVGEKTGIKLLLEHGSLEGIYENIDGMKTSKMKENLINDK  251
            QFIDLKALMGDKSDNIPGVTK+GEKTG+KLL E GSLEGIYE+IDG KTSKMKENLIND+
Sbjct  183  QFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDR  242

Query  252  EQAFLSKTLATIDTKAPIAIGLEDLVYSGPDVENLGKFYDEMGFKQLKQALNVS-SADVS  310
            +QAFLSKTLATI+T +PI+IGL+D+VY+GPDV +L++FYDEM+F QLK++L    + +  
Sbjct  243  DQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEPV  302

Query  311  ESLDFTIVDQISQDMLSEESIFHFELFGENYHTDNLVGFAWSCGDKLYATDKLELLQDPI  370
              + +  V ++S D++S E IF FE + +NYH + ++GFAW+ G+++YA+  L LL    
Sbjct  303  AVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLATDS  362

Query  371  FKDFLEKTSLRVYDFKKVKVLLQRFGVDLQAPAFDIRLAKYLLSTVEDNEIATIASLYGQ  430
            FK+ ++K ++  YDFK+ KVLL ++G++L AP++D RLA+YLLSTVEDNE++TIA ++ +
Sbjct  363  FKQVFQK-PIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIFTD  421

Query  431  TYLVDDETFYGKGVKKAIPEREKFLEHLACKLAVLVETEPILLEKLSENGQLELLYDMEQ  490
              L +D+T YGKG K+A+P+++ +LEHLA K+ VL+++ + +L+KL+ + QL+L  ++E 
Sbjct  422  ISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNIEL  481

Query  491  PLAFVLAKMEIAGIMVKKETLLEMQAENELVIEKLTQEIYELAGEEFNVNSPKQLGVLLF  550
            PLA VLAKMEI GI V++ TL +M  +N ++IE LTQEIY++AG+EFN+NSPKQLG +LF
Sbjct  482  PLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSILF  541

Query  551  EKLGLPLEYTKKTKTGYSTAVDVLERLAPIAPIVKKILDYRQIAKIQSTYVIGLQDWILA  610
            EK+ LPLE TKKTKTGYSTAVDVLERLAPIAPIV KILDYRQI+K+QSTYVIGLQD ILA
Sbjct  542  EKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYILA  601

Query  611  DGKIHTRYVQDLTQTGRLSSVDPNLQNIPARLEQGRLIRKAFVPEWEDSVLLSSDYSQIE  670
            DGKIHTRYVQDLTQTGRLSSVDPNLQNIP RLEQGRLIRKAF P  ED+VLLSSDYSQIE
Sbjct  602  DGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQIE  661

Query  671  LRVLAHISKDEHLIKAFQEGADIHTSTAMRVFGIERPDDVTANDRRNAKAVNFGVVYGIS  730
            LRVLAHIS DEHLI AF+EGADIHTSTAMRVFGI+++ DVTANDRRNAKAVNFG+VYGIS
Sbjct  662  LRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGIS  721

Query  731  DFGLSNNLGISRKEAKAYIDTYFERFPGIKNYMDEVVREARDKGYVETLFKRRRELPDIN  790
            DFGLSNNLGI+RK++K+YIDTYFER+PGIK YM++VVREA+DKGYVETLFKRRRELPDIN
Sbjct  722  DFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDIN  781

Query  791  SRNFNIRGFAERTAINSPIQGSAADILKIAMIQLDKALVAGGYQTKMLLQVHDEIVLEVP  850
            SRNFN+R+FAERTAINSPIQGSAADILKIAMI+LDKAL AGG+++KMLLQVHDEIVLEVP
Sbjct  782  SRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEVP  841

Query  851  KSELVEMKKLVKQTMEEAIQLSVPLIADENEGATWYEAK  889
            + EL  +KKLVK+TME A++L+VPL  DE+ G +WYEAK
Sbjct  842  NDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

102) polA in NC_018630


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score = 1100 bits (4170),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 634/879 (73%), Positives = 771/879 (88%), Gaps = 4/879 (0%)

Query  2    DKKKLLLIDGSSVAFRAFFALYQQLDRFKNAAGLHTNAIYGFQLMLSHLLERVEPSHILV  61
            +K+KLLLIDGSSVAFRAFFALY+Q+DRFKN +GLHTNAIYGF+LML H++ RV P+H+LV
Sbjct  3    NKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLV  62

Query  62   AFDAGKTTFRTEMYADYKGGRAKTPDEFREQFPFIRELLDHMGIRHYELAQYEADDIIGT  121
            AFDAGKTTFRTEMYADYK+GRAKTPDEFREQF++IRE+L  +GI  YEL +YEADDIIGT
Sbjct  63   AFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGT  122

Query  122  LDKLAEQDG--FDITIVSGDKDLIQLTDEHTVVEISKKGVAEFEAFTPDYLMEEMGLTPA  179
            LDK+AE+    FD+TIVSGDKDLIQLTDE+TVVEISKKGVAEFE FTP YLME MGLTP 
Sbjct  123  LDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPN  182

Query  180  QFIDLKALMGDKSDNIPGVTKVGEKTGIKLLLEHGSLEGIYENIDGMKTSKMKENLINDK  239
            QFIDLKALMGDKSDNIPGVTK+GEKTG+KLL E GSLEGIYE+IDG KTSKMKENLIND+
Sbjct  183  QFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDR  242

Query  240  EQAFLSKTLATIDTKAPIAIGLEDLVYSGPDVENLGKFYDEMGFKQLKQALNVS-SADVS  298
            +QAFLSKTLATI+T +PI+IGL+D+VY+GPDV +L++FYDEM+F QLK++L    + +  
Sbjct  243  DQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEPV  302

Query  299  ESLDFTIVDQISQDMLSEESIFHFELFGENYHTDNLVGFAWSCGDKLYATDKLELLQDPI  358
              + +  V ++S D++S E IF FE + +NYH + ++GFAW+ G+++YA+  L LL    
Sbjct  303  AVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLATDS  362

Query  359  FKDFLEKTSLRVYDFKKVKVLLQRFGVDLQAPAFDIRLAKYLLSTVEDNEIATIASLYGQ  418
            FK+ ++K ++  YDFK+ KVLL ++G++L AP++D RLA+YLLSTVEDNE++TIA ++ +
Sbjct  363  FKQVFQK-PIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIFTD  421

Query  419  TYLVDDETFYGKGVKKAIPEREKFLEHLACKLAVLVETEPILLEKLSENGQLELLYDMEQ  478
              L +D+T YGKG K+A+P+++ +LEHLA K+ VL+++ + +L+KL+ + QL+L  ++E 
Sbjct  422  ISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNIEL  481

Query  479  PLAFVLAKMEIAGIMVKKETLLEMQAENELVIEKLTQEIYELAGEEFNVNSPKQLGVLLF  538
            PLA VLAKMEI GI V++ TL +M  +N ++IE LTQEIY++AG+EFN+NSPKQLG +LF
Sbjct  482  PLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSILF  541

Query  539  EKLGLPLEYTKKTKTGYSTAVDVLERLAPIAPIVKKILDYRQIAKIQSTYVIGLQDWILA  598
            EK+ LPLE TKKTKTGYSTAVDVLERLAPIAPIV KILDYRQI+K+QSTYVIGLQD ILA
Sbjct  542  EKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYILA  601

Query  599  DGKIHTRYMQDLTQTGRLSSVDPNLQNIPARLEQGRLIRKAFVPEWEDSVLLSSDYSQIE  658
            DGKIHTRY+QDLTQTGRLSSVDPNLQNIP RLEQGRLIRKAF P  ED+VLLSSDYSQIE
Sbjct  602  DGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQIE  661

Query  659  LRVLAHISKDEHLIKAFQEGADIHTSTAMRVFGIERPDNVTANDRRNAKAVNFGVVYGIS  718
            LRVLAHIS DEHLI AF+EGADIHTSTAMRVFGI+++ +VTANDRRNAKAVNFG+VYGIS
Sbjct  662  LRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGIS  721

Query  719  DFGLSNNLGISRKEAKAYIDTYFERFPGIKNYMDEVVREARDKGYVETLFKRRRELPDIN  778
            DFGLSNNLGI+RK++K+YIDTYFER+PGIK YM++VVREA+DKGYVETLFKRRRELPDIN
Sbjct  722  DFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDIN  781

Query  779  SRNFNIRGFAERTAINSPIQGSAADILKIAMIQLDKALVAGGYQTKMLLQVHDEIVLEVP  838
            SRNFN+R+FAERTAINSPIQGSAADILKIAMI+LDKAL AGG+++KMLLQVHDEIVLEVP
Sbjct  782  SRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEVP  841

Query  839  KSELVEMKKLVKQTMEEAIQLSVPLIADENEGATWYEAK  877
            + EL  +KKLVK+TME A++L+VPL  DE+ G +WYEAK
Sbjct  842  NDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

103) polA in NC_017593


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score = 1100 bits (4171),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 634/879 (73%), Positives = 771/879 (88%), Gaps = 4/879 (0%)

Query  2    DKKKLLLIDGSSVAFRAFFALYQQLDRFKNVAGLHTNAIYGFQLMLSHLLERVEPSHILV  61
            +K+KLLLIDGSSVAFRAFFALY+Q+DRFKN +GLHTNAIYGF+LML H++ RV P+H+LV
Sbjct  3    NKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLV  62

Query  62   AFDAGKTTFRTEMYADYKGGRAKTPDEFREQFPFIRELLDHMGIRHYDLAQYEADDIIGT  121
            AFDAGKTTFRTEMYADYK+GRAKTPDEFREQF++IRE+L  +GI  Y+L +YEADDIIGT
Sbjct  63   AFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGT  122

Query  122  LDKLAEQDG--FDITIVSGDKDLIQLTDEHTVVEISKKGVSEFEAFTPDYLMEEMGLTPA  179
            LDK+AE+    FD+TIVSGDKDLIQLTDE+TVVEISKKGV+EFE FTP YLME MGLTP 
Sbjct  123  LDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPN  182

Query  180  QFIDLKALMGDKSDNIPGVTKVGEKTGIKLLLEHGSLEGIYENIDGMKTSKMKENLINDK  239
            QFIDLKALMGDKSDNIPGVTK+GEKTG+KLL E GSLEGIYE+IDG KTSKMKENLIND+
Sbjct  183  QFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDR  242

Query  240  EQAFLSKTLATIDTKAPIAIGLEDLVYSGPDVENLGKFYDEMGFKQLKQALNVS-SADVS  298
            +QAFLSKTLATI+T +PI+IGL+D+VY+GPDV +L++FYDEM+F QLK++L    + +  
Sbjct  243  DQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEPV  302

Query  299  ESLDFTIVDQISQDMLSEESIFHFELFGENYHTDNLVGFAWSCGDKLYATDKLELLQDPI  358
              + +  V ++S D++S E IF FE + +NYH + ++GFAW+ G+++YA+  L LL    
Sbjct  303  AVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLATDS  362

Query  359  FKDFLEKTSLRVYDFKKVKVLLQRFGVDLQAPAFDIRLAKYLLSTVEDNEIATIASLYGQ  418
            FK+ ++K ++  YDFK+ KVLL ++G++L AP++D RLA+YLLSTVEDNE++TIA ++ +
Sbjct  363  FKQVFQK-PIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIFTD  421

Query  419  TYLVDDETFYGKGVKKAIPEREKFLEHLACKLAVLVETEPILLEKLSENGQLELLYDMEQ  478
              L +D+T YGKG K+A+P+++ +LEHLA K+ VL+++ + +L+KL+ + QL+L  ++E 
Sbjct  422  ISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNIEL  481

Query  479  PLAFVLAKMEIAGIMVKKETLLEMQAENELVIEKLTQEIYELAGEEFNVNSPKQLGVLLF  538
            PLA VLAKMEI GI V++ TL +M  +N ++IE LTQEIY++AG+EFN+NSPKQLG +LF
Sbjct  482  PLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSILF  541

Query  539  EKLGLPLEYTKKTKTGYSTAVDVLERLAPIAPIVKKILDYRQIAKIQSTYVIGLQDWILA  598
            EK+ LPLE TKKTKTGYSTAVDVLERLAPIAPIV KILDYRQI+K+QSTYVIGLQD ILA
Sbjct  542  EKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYILA  601

Query  599  DGKIHTRYVQDLTQTGRLSSVDPNLQNIPARLEQGRLIRKAFVPEWEDSVLLSSDYSQIE  658
            DGKIHTRYVQDLTQTGRLSSVDPNLQNIP RLEQGRLIRKAF P  ED+VLLSSDYSQIE
Sbjct  602  DGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQIE  661

Query  659  LRVLAHISKDEHLIKAFQEGADIHTSTAMRVFGIERPDDVTANDRRNAKAVNFGVVYGIS  718
            LRVLAHIS DEHLI AF+EGADIHTSTAMRVFGI+++ DVTANDRRNAKAVNFG+VYGIS
Sbjct  662  LRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGIS  721

Query  719  DFGLSNNLGISRKEAKAYIDTYFERFPGIKNYMDEVVREARDKGYVETLFKRRRELPDIN  778
            DFGLSNNLGI+RK++K+YIDTYFER+PGIK YM++VVREA+DKGYVETLFKRRRELPDIN
Sbjct  722  DFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDIN  781

Query  779  SRNFNIRGFAERTAINSPIQGSAADILKIAMIQLDKALVAGGYQTKMLLQVHDEIVLEVP  838
            SRNFN+R+FAERTAINSPIQGSAADILKIAMI+LDKAL AGG+++KMLLQVHDEIVLEVP
Sbjct  782  SRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEVP  841

Query  839  KSELVEMKKLVKQTMEEAIQLSVPLIADENEGATWYEAK  877
            + EL  +KKLVK+TME A++L+VPL  DE+ G +WYEAK
Sbjct  842  NDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

104) SPP_0095 in NC_012467


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score = 1100 bits (4170),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 634/879 (73%), Positives = 771/879 (88%), Gaps = 4/879 (0%)

Query  2    DKKKLLLIDGSSVAFRAFFALYQQLDRFKNAAGLHTNAIYGFQLMLSHLLERVEPSHILV  61
            +K+KLLLIDGSSVAFRAFFALY+Q+DRFKN +GLHTNAIYGF+LML H++ RV P+H+LV
Sbjct  3    NKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLV  62

Query  62   AFDAGKTTFRTEMYADYKGGRAKTPDEFREQFPFIRELLDHMGIRHYELAQYEADDIIGT  121
            AFDAGKTTFRTEMYADYK+GRAKTPDEFREQF++IRE+L  +GI  YEL +YEADDIIGT
Sbjct  63   AFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGT  122

Query  122  LDKLAEQDG--FDITIVSGDKDLIQLTDEHTVVEISKKGVAEFEAFTPDYLMEEMGLTPA  179
            LDK+AE+    FD+TIVSGDKDLIQLTDE+TVVEISKKGVAEFE FTP YLME MGLTP 
Sbjct  123  LDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPN  182

Query  180  QFIDLKALMGDKSDNIPGVTKVGEKTGIKLLLEHGSLEGIYENIDGMKTSKMKENLINDK  239
            QFIDLKALMGDKSDNIPGVTK+GEKTG+KLL E GSLEGIYE+IDG KTSKMKENLIND+
Sbjct  183  QFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDR  242

Query  240  EQAFLSKTLATIDTKAPIAIGLEDLVYSGPDVENLGKFYDEMGFKQLKQALNVS-SADVS  298
            +QAFLSKTLATI+T +PI+IGL+D+VY+GPDV +L++FYDEM+F QLK++L    + +  
Sbjct  243  DQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEPV  302

Query  299  ESLDFTIVDQISQDMLSEESIFHFELFGENYHTDNLVGFAWSCGDKLYATDKLELLQDPI  358
              + +  V ++S D++S E IF FE + +NYH + ++GFAW+ G+++YA+  L LL    
Sbjct  303  AVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLATDS  362

Query  359  FKDFLEKTSLRVYDFKKVKVLLQRFGVDLQAPAFDIRLAKYLLSTVEDNEIATIASLYGQ  418
            FK+ ++K ++  YDFK+ KVLL ++G++L AP++D RLA+YLLSTVEDNE++TIA ++ +
Sbjct  363  FKQVFQK-PIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIFTD  421

Query  419  TYLVDDETFYGKGVKKAIPEREKFLEHLACKLAVLVETEPILLEKLSENGQLELLYDMEQ  478
              L +D+T YGKG K+A+P+++ +LEHLA K+ VL+++ + +L+KL+ + QL+L  ++E 
Sbjct  422  ISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNIEL  481

Query  479  PLAFVLAKMEIAGIMVKKETLLEMQAENELVIEKLTQEIYELAGEEFNVNSPKQLGVLLF  538
            PLA VLAKMEI GI V++ TL +M  +N ++IE LTQEIY++AG+EFN+NSPKQLG +LF
Sbjct  482  PLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSILF  541

Query  539  EKLGLPLEYTKKTKTGYSTAVDVLERLAPIAPIVKKILDYRQIAKIQSTYVIGLQDWILA  598
            EK+ LPLE TKKTKTGYSTAVDVLERLAPIAPIV KILDYRQI+K+QSTYVIGLQD ILA
Sbjct  542  EKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYILA  601

Query  599  DGKIHTRYMQDLTQTGRLSSVDPNLQNIPARLEQGRLIRKAFVPEWEDSVLLSSDYSQIE  658
            DGKIHTRY+QDLTQTGRLSSVDPNLQNIP RLEQGRLIRKAF P  ED+VLLSSDYSQIE
Sbjct  602  DGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQIE  661

Query  659  LRVLAHISKDEHLIKAFQEGADIHTSTAMRVFGIERPDNVTANDRRNAKAVNFGVVYGIS  718
            LRVLAHIS DEHLI AF+EGADIHTSTAMRVFGI+++ +VTANDRRNAKAVNFG+VYGIS
Sbjct  662  LRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGIS  721

Query  719  DFGLSNNLGISRKEAKAYIDTYFERFPGIKNYMDEVVREARDKGYVETLFKRRRELPDIN  778
            DFGLSNNLGI+RK++K+YIDTYFER+PGIK YM++VVREA+DKGYVETLFKRRRELPDIN
Sbjct  722  DFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDIN  781

Query  779  SRNFNIRGFAERTAINSPIQGSAADILKIAMIQLDKALVAGGYQTKMLLQVHDEIVLEVP  838
            SRNFN+R+FAERTAINSPIQGSAADILKIAMI+LDKAL AGG+++KMLLQVHDEIVLEVP
Sbjct  782  SRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEVP  841

Query  839  KSELVEMKKLVKQTMEEAIQLSVPLIADENEGATWYEAK  877
            + EL  +KKLVK+TME A++L+VPL  DE+ G +WYEAK
Sbjct  842  NDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

105) SP_0032 in NC_003028


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score = 1100 bits (4169),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 634/879 (73%), Positives = 770/879 (88%), Gaps = 4/879 (0%)

Query  2    DKKKLLLIDGSSVAFRAFFALYQQLDRFKNVAGLHTNAIYGFQLMLSHLLERVEPSHILV  61
            +K+KLLLIDGSSVAFRAFFALY+Q+DRFKN +GLHTNAIYGF+LML H++ RV P+H+LV
Sbjct  3    NKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLV  62

Query  62   AFDAGKTTFRTEMYADYKGGRAKTPDEFREQFPFIRELLDHMGIRHYDLAQYEADDIIGT  121
            AFDAGKTTFRTEMYADYK+GRAKTPDEFREQF++IRE+L  +GI  Y+L +YEADDIIGT
Sbjct  63   AFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGT  122

Query  122  LDKLAEQDG--FDITIVSGDKDLIQLTDEHTVVEISKKGVAEFEAFTPDYLMEEMGLTPA  179
            LDK+AE+    FD+TIVSGDKDLIQLTDE+TVVEISKKGVAEFE FTP YLME MGLTP 
Sbjct  123  LDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPN  182

Query  180  QFIDLKALMGDKSDNIPGVTKVGEKTGIKLLLEHGSLEGIYENIDGMKTSKMKENLINDK  239
            QFIDLKALMGDKSDNIPGVTK+GEKTG+KLL E GSLEGIYE+IDG KTSKMKENLIND+
Sbjct  183  QFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDR  242

Query  240  EQAFLSKTLATIDTKAPIAIGLEDLVYSGPDVENLGKFYDEMGFKQLKQALNVS-SADVS  298
            +QAFLSKTLATI+T +PI+IGL+D+VY+GPDV +L++FYDEM+F QLK++L    + +  
Sbjct  243  DQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEPV  302

Query  299  ESLDFTIVDQISQDMLSEESIFHFELFGENYHTDNLVGFVWSCGDKLYATDKLELLQDPI  358
              + +  V ++S D++S E IF FE + +NYH + ++GF W+ G+++YA+  L LL    
Sbjct  303  AVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLATDS  362

Query  359  FKDFLEKTSLRVYDFKKVKVLLQRFGVDLQAPAFDIRLAKYLLSTVEDNEIATIASLYGQ  418
            FK+ ++K ++  YDFK+ KVLL ++G++L AP++D RLA+YLLSTVEDNE++TIA ++ +
Sbjct  363  FKQVFQK-PIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIFTD  421

Query  419  TYLVDDETFYGKGVKKAIPEREKFLEHLACKLAVLVETEPILLEKLSENGQLELLYDMEQ  478
              L +D+T YGKG K+A+P+++ +LEHLA K+ VL+++ + +L+KL+ + QL+L  ++E 
Sbjct  422  ISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNIEL  481

Query  479  PLAFVLAKMEIAGIMVKKETLLEMQAENELVIEKLTQEIYELAGEEFNVNSPKQLGVLLF  538
            PLA VLAKMEI GI V++ TL +M  +N ++IE LTQEIY++AG+EFN+NSPKQLG +LF
Sbjct  482  PLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSILF  541

Query  539  EKLGLPLEYTKKTKTGYSTAVDVLERLAPIAPIVKKILDYRQIAKIQSTYVIGLQDWILA  598
            EK+ LPLE TKKTKTGYSTAVDVLERLAPIAPIV KILDYRQI+K+QSTYVIGLQD ILA
Sbjct  542  EKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYILA  601

Query  599  DGKIHTRYVQDLTQTGRLSSVDPNLQNIPARLEQGRLIRKAFVPEWEDSVLLSSDYSQIE  658
            DGKIHTRYVQDLTQTGRLSSVDPNLQNIP RLEQGRLIRKAF P  ED+VLLSSDYSQIE
Sbjct  602  DGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQIE  661

Query  659  LRVLAHISKDEHLIKAFQEGADIHTSTAMRVFGIERPDDVTANDRRNAKAVNFGVVYGIS  718
            LRVLAHIS DEHLI AF+EGADIHTSTAMRVFGI+++ DVTANDRRNAKAVNFG+VYGIS
Sbjct  662  LRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGIS  721

Query  719  DFGLSNNLGISRKEAKAYIDTYFERFPGIKNYMDEVVREARDKGYVETLFKRRRELPDIN  778
            DFGLSNNLGI+RK++K+YIDTYFER+PGIK YM++VVREA+DKGYVETLFKRRRELPDIN
Sbjct  722  DFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDIN  781

Query  779  SRNFNIRGFAERTAINSPIQGSAADILKIAMIQLDKALVAGGYQTKMLLQVHDEIVLEVP  838
            SRNFN+R+FAERTAINSPIQGSAADILKIAMI+LDKAL AGG+++KMLLQVHDEIVLEVP
Sbjct  782  SRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEVP  841

Query  839  KSELVEMKKLVKQTMEEAIQLSVPLIADENEGATWYEAK  877
            + EL  +KKLVK+TME A++L+VPL  DE+ G +WYEAK
Sbjct  842  NDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

106) polA in NC_017591


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score = 1099 bits (4166),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 634/879 (73%), Positives = 771/879 (88%), Gaps = 4/879 (0%)

Query  2    DKKKLLLIDGSSVAFRAFFALYQQLDRFKNAAGLHTNAIYGFQLMLSHLLERVEPSHILV  61
            +K+KLLLIDGSSVAFRAFFALY+Q+DRFKN +GLHTNAIYGF+LML H++ RV P+H+LV
Sbjct  3    NKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLV  62

Query  62   AFDAGKTTFRTEMYADYKGGRAKTPDEFREQFPFIRELLDHMGIRHYELAQYEADDIIGT  121
            AFDAGKTTFRTEMYADYK+GRAKTPDEFREQF++IRE+L  +GI  YEL +YEADDIIGT
Sbjct  63   AFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGT  122

Query  122  LDKLAEQDG--FDITIVSGDKDLIQLTDEHTVVEISKKGVAEFEAFTPDYLMEEMGLTPA  179
            LDK+AE+    FD+TIVSGDKDLIQLTDE+TVVEISKKGVAEFE FTP YLME MGLTP 
Sbjct  123  LDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPN  182

Query  180  QFIDLKALMGDKSDNIPGVTKVGEKTGIKLLLEHGSLEGIYENIDGMKTSKMKENLINDK  239
            QFIDLKALMGDKSDNIPGVTK+GEKTG+KLL E GSLEGIYE+IDG KTSKMKENLIND+
Sbjct  183  QFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDR  242

Query  240  EQAFLSKTLATIDTKAPIAIGLEDLVYSGPDVENLGKFYDEMGFKQLKQALNVS-SADVA  298
            +QAFLSKTLATI+T +PI+IGL+D+VY+GPDV +L++FYDEM+F QLK++L    + +  
Sbjct  243  DQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEPV  302

Query  299  EGLDFTIVDQISQDMLSEESIFHFELFGENYHTDNLVGFAWSCGDKLYATDKLELLQDPI  358
              + +  V ++S D++S E IF FE + +NYH + ++GFAW+ G+++YA+  L LL    
Sbjct  303  AVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLATDS  362

Query  359  FKDFLEKTSLRVYDFKKVKVLLQRFGVDLQAPAFDIRLAKYLLSTVEDNEIATIASLYGQ  418
            FK+ ++K ++  YDFK+ KVLL ++G++L AP++D RLA+YLLSTVEDNE++TIA ++ +
Sbjct  363  FKQVFQK-PIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIFTD  421

Query  419  TYLVDDETFYGKGVKKAIPEREKFLEHLACKLAVLVETEPILLEKLSENGQLELLYDMEQ  478
              L +D+T YGKG K+A+P+++ +LEHLA K+ VL+++ + +L+KL+ + QL+L  ++E 
Sbjct  422  ISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNIEL  481

Query  479  PLAFVLAKMEIAGIVVKKETLLEMQAENELVIEKLTQEIYELAGEEFNVNSPKQLGVLLF  538
            PLA VLAKMEI GI V++ TL +M  +N ++IE LTQEIY++AG+EFN+NSPKQLG +LF
Sbjct  482  PLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSILF  541

Query  539  EKLGLPLEYTKKTKTGYSTAVDVLERLAPIAPIVKKILDYRQIAKIQSTYVIGLQDWILA  598
            EK+ LPLE TKKTKTGYSTAVDVLERLAPIAPIV KILDYRQI+K+QSTYVIGLQD ILA
Sbjct  542  EKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYILA  601

Query  599  DGKIHTRYMQDLTQTGRLSSVDPNLQNIPARLEQGRLIRKAFVPEWEDSVLLSSDYSQIE  658
            DGKIHTRY+QDLTQTGRLSSVDPNLQNIP RLEQGRLIRKAF P  ED+VLLSSDYSQIE
Sbjct  602  DGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQIE  661

Query  659  LRVLAHISKDEHLIKAFQEGADIHTSTAMRVFGIERPDNVTANDRRNAKAVNFGVVYGIS  718
            LRVLAHIS DEHLI AF+EGADIHTSTAMRVFGI+++ +VTANDRRNAKAVNFG+VYGIS
Sbjct  662  LRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGIS  721

Query  719  DFGLSNNLGISRKEAKAYIDTYFERFPGIKNYMDEVVREARDKGYVETLFKRRRELPDIN  778
            DFGLSNNLGI+RK++K+YIDTYFER+PGIK YM++VVREA+DKGYVETLFKRRRELPDIN
Sbjct  722  DFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDIN  781

Query  779  SRNFNIRGFAERTAINSPIQGSAADILKIAMIQLDKALVAGGYQTKMLLQVHDEIVLEVP  838
            SRNFN+R+FAERTAINSPIQGSAADILKIAMI+LDKAL AGG+++KMLLQVHDEIVLEVP
Sbjct  782  SRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEVP  841

Query  839  KSELVEMKKLVKQTMEEAIQLSVPLIADENEGATWYEAK  877
            + EL  +KKLVK+TME A++L+VPL  DE+ G +WYEAK
Sbjct  842  NDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

107) polA in NC_021006


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score = 1099 bits (4167),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 635/879 (73%), Positives = 771/879 (88%), Gaps = 4/879 (0%)

Query  2    DKKKLLLIDGSSVAFRAFFALYQQLDRFKNAAGLHTNAIYGFQLMLSHLLERVEPSHILV  61
            +K+KLLLIDGSSVAFRAFFALY+Q+DRFKN +GLHTNAIYGF+LML H++ RV P+H+LV
Sbjct  3    NKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLV  62

Query  62   AFDAGKTTFRTEMYADYKGGRAKTPDEFREQFPFIRELLDHMGIRHYELAQYEADDIIGT  121
            AFDAGKTTFRTEMYADYK+GRAKTPDEFREQF++IRE+L  +GI  YEL +YEADDIIGT
Sbjct  63   AFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGT  122

Query  122  LDKLAEQDG--FDITIVSGDKDLIQLTDEHTVVEISKKGVAEFEAFTPDYLMEEMGLTPA  179
            LDK+AE+    FD+TIVSGDKDLIQLTDE+TVVEISKKGVAEFE FTP YLME MGLTP 
Sbjct  123  LDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPN  182

Query  180  QFIDLKALMGDKSDNIPGVTKVGEKTGVKLLLEHGSLEGIYENIDGMKTSKMKENLINDK  239
            QFIDLKALMGDKSDNIPGVTK+GEKTG+KLL E GSLEGIYE+IDG KTSKMKENLIND+
Sbjct  183  QFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDR  242

Query  240  EQAFLSKTLATIDTKAPIAIGLEDLVYSGPDVENLGKFYDEMGFKQLKQALNVS-SADVA  298
            +QAFLSKTLATI+T +PI+IGL+D+VY+GPDV +L++FYDEM+F QLK++L    + +  
Sbjct  243  DQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEPV  302

Query  299  EGLDFTIVDQISQDMLSEESIFHIELFGENYHTDNLVGFAWSCGDKLYATDKLELLQDPI  358
              + +  V ++S D++S E IF +E + +NYH + ++GFAW+ G+++YA+  L LL    
Sbjct  303  AVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLATDS  362

Query  359  FKDFLEKTSLRVYDFKKVKVLLQRFGVDLQAPAFDIRLAKYLLSTVEDNEIATIASLYGQ  418
            FK+ ++K ++  YDFK+ KVLL ++G++L AP++D RLA+YLLSTVEDNE++TIA ++ +
Sbjct  363  FKQVFQK-PIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIFTD  421

Query  419  TYLVDDETFYGKGVKKAIPEREKFLEHLACKLAVLVETEPILLEKLSENGQLELLYDMEQ  478
              L +D+T YGKG K+A+P+++ +LEHLA K+ VL+++ + +L+KL+ + QL+L  ++E 
Sbjct  422  ISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNIEL  481

Query  479  PLAFVLAKMEIAGIMVKKETLLEMQAENELVIEKLTQEIYELAGEEFNVNSPKQLGVLLF  538
            PLA VLAKMEI GI V++ TL +M  +N ++IE LTQEIY++AG+EFN+NSPKQLG +LF
Sbjct  482  PLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSILF  541

Query  539  EKLGLPLEYTKKTKTGYSTAVDVLERLAPIAPIVKKILDYRQIAKIQSTYVIGLQDWILA  598
            EK+ LPLE TKKTKTGYSTAVDVLERLAPIAPIV KILDYRQI+K+QSTYVIGLQD ILA
Sbjct  542  EKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYILA  601

Query  599  DGKIHTRYVQDLTQTGRLSSVDPNLQNIPARLEQGRLIRKAFVPEWEDSVLLSSDYSQIE  658
            DGKIHTRYVQDLTQTGRLSSVDPNLQNIP RLEQGRLIRKAF P  ED+VLLSSDYSQIE
Sbjct  602  DGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQIE  661

Query  659  LRVLAHISKDEHLIKAFQEGADIHTSTAMRVFGIERPDDVTANDRRNAKAVNFGVVYGIS  718
            LRVLAHIS DEHLI AF+EGADIHTSTAMRVFGI+++ DVTANDRRNAKAVNFG+VYGIS
Sbjct  662  LRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGIS  721

Query  719  DFGLSNNLGISRKEAKAYIDTYFERFPGIKNYMDEVVREARDKGYVETLFKRRRELPDIN  778
            DFGLSNNLGI+RK++K+YIDTYFER+PGIK YM++VVREA+DKGYVETLFKRRRELPDIN
Sbjct  722  DFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDIN  781

Query  779  SRNFNIRGFAERTAINSPIQGSAADILKIAMIQLDKALVAGGYQTKMLLQVHDEIVLEVP  838
            SRNFN+R+FAERTAINSPIQGSAADILKIAMI+LDKAL AGG+++KMLLQVHDEIVLEVP
Sbjct  782  SRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEVP  841

Query  839  KSELVEMKKLVKQTMEEAIQLSVPLIADENEGATWYEAK  877
            + EL  +KKLVK+TME A++L+VPL  DE+ G +WYEAK
Sbjct  842  NDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

108) polA in NC_010582


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score = 1098 bits (4165),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 634/879 (73%), Positives = 771/879 (88%), Gaps = 4/879 (0%)

Query  14   DKKKLLLIDGSSVAFRAFFALYQQLDRFKNVAGLHTNAIYGFQLMLSHLLERVEPSHILV  73
            +K+KLLLIDGSSVAFRAFFALY+Q+DRFKN +GLHTNAIYGF+LML H++ RV P+H+LV
Sbjct  3    NKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLV  62

Query  74   AFDAGKTTFRTEMYADYKGGRAKTPDEFREQFPFIRELLDHMGIRHYDLAQYEADDIIGT  133
            AFDAGKTTFRTEMYADYK+GRAKTPDEFREQF++IRE+L  +GI  Y+L +YEADDIIGT
Sbjct  63   AFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGT  122

Query  134  LDKLAEQDG--FDITIVSGDKDLIQLTDEHTVVEISKKGVSEFEAFTPDYLMEEMGLTPA  191
            LDK+AE+    FD+TIVSGDKDLIQLTDE+TVVEISKKGV+EFE FTP YLME MGLTP 
Sbjct  123  LDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPN  182

Query  192  QFIDLKALMGDKSDNIPGVTKVGEKTGIKLLLEHGSLEGIYENIDGMKTSKMKENLINDK  251
            QFIDLKALMGDKSDNIPGVTK+GEKTG+KLL E GSLEGIYE+IDG KTSKMKENLIND+
Sbjct  183  QFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDR  242

Query  252  EQAFLSKTLATIDTKAPIAIGLEDLVYSGPDVENLGKFYDEMGFKQLKQALNVS-SADVS  310
            +QAFLSKTLATI+T +PI+IGL+D+VY+GPDV +L++FYDEM+F QLK++L    + +  
Sbjct  243  DQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEPV  302

Query  311  ESLDFTIVDQISQDMLSEESIFHFELFGENYHTDNLVGFAWSCGDKLYATDKLELLQDPI  370
              + +  V ++S D++S E IF FE + +NYH + ++GFAW+ G+++YA+  L LL    
Sbjct  303  AVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLATDS  362

Query  371  FKDFLEKTSLRVYDFKKVKVLLQRFGVDLQAPAFDIRLAKYLLSTVEDNEIATIASLYGQ  430
            FK+ ++K ++  YDFK+ KVLL ++G++L AP++D RLA+YLLSTVEDNE++TIA ++ +
Sbjct  363  FKQVFQK-PIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIFTD  421

Query  431  TYLVDDETFYGKGVKKAIPEREKFLEHLACKLAVLVETEPILLEKLSENGQLELLYDMEQ  490
              L +D+T YGKG K+A+P+++ +LEHLA K+ VL+++ + +L+KL+ + QL+L  ++E 
Sbjct  422  ISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNIEL  481

Query  491  PLAFVLAKMEIAGIMVKKETLLEMQAENELVIEKLTQEIYELAGEEFNVNSPKQLGVLLF  550
            PLA VLAKMEI GI V++ TL +M  +N ++IE LTQEIY++AG+EFN+NSPKQLG +LF
Sbjct  482  PLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSILF  541

Query  551  EKLGLPLEYTKKTKTGYSTAVDVLERLAPIAPIVKKILDYRQIAKIQSTYVIGLQDWILA  610
            EK+ LPLE TKKTKTGYSTAVDVLERLAPIAPIV KILDYRQI+K+QSTYVIGLQD ILA
Sbjct  542  EKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYILA  601

Query  611  DGKIHTRYVQDLTQTGRLSSVDPNLQNIPARLEQGRLIRKAFVPEWEDSVLLSSDYSQIE  670
            DGKIHTRYVQDLTQTGRLSSVDPNLQNIP RLEQGRLIRKAF P  ED+VLLSSDYSQIE
Sbjct  602  DGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQIE  661

Query  671  LRVLAHISKDEHLIKAFQEGADIHTSTAMRVFGIERPDDVTANDRRNAKAVNFGVVYGIS  730
            LRVLAHIS DEHLI AF+EGADIHTSTAMRVFGI+++ DVTANDRRNAKAVNFG+VYGIS
Sbjct  662  LRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGIS  721

Query  731  DFGLSNNLGISRKEAKAYIDTYFERFPGIKNYMDEVVREARDKGYVETLFKRRRELPDIN  790
            DFGLSNNLGI+RK++K+YIDTYFER+PGIK YM++VVREA+DKGYVETLFKRRRELPDIN
Sbjct  722  DFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDIN  781

Query  791  SRNFNIRGFAERTAINSPIQGSAADILKIAMIQLDKALVAGGYQTKMLLQVHDEIVLEVP  850
            SRNFN+R+FAERTAINSPIQGSAADILKIAMI+LDKAL AGG+++KMLLQVHDEIVLEVP
Sbjct  782  SRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEVP  841

Query  851  KSELVEMKKLVKQTMEEAIQLSVPLIADENEGATWYEAK  889
            + EL  +KKLVK+TME A++L+VPL  DE+ G +WYEAK
Sbjct  842  NDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

109) SPH_0131 in NC_010380


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score = 1098 bits (4164),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 634/879 (73%), Positives = 770/879 (88%), Gaps = 4/879 (0%)

Query  2    DKKKLLLIDGSSVAFRAFFALYQQLDRFKNAAGLHTNAIYGFQLMLSHLLERVEPSHILV  61
            +K+KLLLIDGSSVAFRAFFALY+Q+DRFKN +GLHTNAIYGF+LML H++ RV P+H+LV
Sbjct  3    NKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLV  62

Query  62   AFDAGKTTFRTEMYADYKGGRAKTPDEFREQFPFIRELLDHMGIRHYELAQYEADDIIGT  121
            AFDAGKTTFRTEMYADYK+GRAKTPDEFREQF++IRE+L  +GI  YEL +YEADDIIGT
Sbjct  63   AFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGT  122

Query  122  LDKLAEQDG--FDITIVSGDKDLIQLTDEHTVVEISKKGVAEFEAFTPDYLMEEMGLTPA  179
            LDK+AE+    FD+TIVSGDKDLIQLTDE+TVVEISKKGVAEFE FTP YLME MGLTP 
Sbjct  123  LDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPN  182

Query  180  QFIDLKALMGDKSDNIPGVTKVGEKTGIKLLLEHGSLEGIYENIDGMKTSKMKENLINDK  239
            QFIDLKALMGDKSDNIPGVTK+GEKTG+KLL E GSLEGIYE+IDG KTSKMKENLIND+
Sbjct  183  QFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDR  242

Query  240  EQAFLSKTLATIDTKAPIAIGLEDLVYSGPDVENLGKFYDEMGFKQLKQALNVS-SADVA  298
            +QAFLSKTLATI+T +PI+IGL+D+VY+GPDV +L++FYDEM+F QLK++L    + +  
Sbjct  243  DQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEPV  302

Query  299  KGLDFTIVDQISQDMLSEESIFHFELFGENYHTDNLVGFAWSCEDKLYATDKLELLQDPI  358
              + +  V ++S D++S E IF FE + +NYH + ++GFAW+  +++YA+  L LL    
Sbjct  303  AVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLATDS  362

Query  359  FKDFLEKTSLRVYDFKKVKVLLQRFGVDLQAPAFDIRLAKYLLSTVEDNEIATIASLYGQ  418
            FK+ ++K ++  YDFK+ KVLL ++G++L AP++D RLA+YLLSTVEDNE++TIA ++ +
Sbjct  363  FKQVFQK-PIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIFTD  421

Query  419  TYLVDDETFYGKGVKKAIPEREKFLEHLACKLAVLVETEPILLEKLSENGQLELLYDMEQ  478
              L +D+T YGKG K+A+P+++ +LEHLA K+ VL+++ + +L+KL+ + QL+L  ++E 
Sbjct  422  ISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNIEL  481

Query  479  PLAFVLAKMEIAGIMVKKETLLEMQAENELVIEKLTQEIYELAGEEFNVNSPKQLGVLLF  538
            PLA VLAKMEI GI V++ TL +M  +N ++IE LTQEIY++AG+EFN+NSPKQLG +LF
Sbjct  482  PLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSILF  541

Query  539  EKLGLPLEYTKKTKTGYSTAVDVLERLAPIAPIVKKILDYRQIAKIQSTYVIGLQDWILA  598
            EK+ LPLE TKKTKTGYSTAVDVLERLAPIAPIV KILDYRQI+K+QSTYVIGLQD ILA
Sbjct  542  EKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYILA  601

Query  599  DGKIHTRYVQDLTQTGRLSSVDPNLQNIPARLEQGRLIRKAFVPEWEDSVLLSSDYSQIE  658
            DGKIHTRYVQDLTQTGRLSSVDPNLQNIP RLEQGRLIRKAF P  ED+VLLSSDYSQIE
Sbjct  602  DGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQIE  661

Query  659  LRVLAHISKDEHLIKAFQEGADIHTSTAMRVFGIERPDDVTANDRRNAKAVNFGVVYGIS  718
            LRVLAHIS DEHLI AF+EGADIHTSTAMRVFGI+++ DVTANDRRNAKAVNFG+VYGIS
Sbjct  662  LRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGIS  721

Query  719  DFGLSNNLGISRKEAKAYIDTYFERFPGIKNYMDEVVREARDKSYVETLFKRRRELPDIN  778
            DFGLSNNLGI+RK++K+YIDTYFER+PGIK YM++VVREA+DK+YVETLFKRRRELPDIN
Sbjct  722  DFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDIN  781

Query  779  SRNFNIRGFAERTAINSPIQGSAADILKIAMIQLDKALVAGGYQTKMLLQVHDEIVLEVP  838
            SRNFN+R+FAERTAINSPIQGSAADILKIAMI+LDKAL AGG+++KMLLQVHDEIVLEVP
Sbjct  782  SRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEVP  841

Query  839  KSELVEMKKLVKQTMEEAIQLSVPLIADENEGATWYEAK  877
            + EL  +KKLVK+TME A++L+VPL  DE+ G +WYEAK
Sbjct  842  NDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

110) polA in NC_017592


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score = 1098 bits (4163),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 635/879 (73%), Positives = 771/879 (88%), Gaps = 4/879 (0%)

Query  2    DKKKLLLIDGSSVAFRAFFALYQQLDRFKNAAGLHTNAIYGFQLMLSHLLERVEPSHILV  61
            +K+KLLLIDGSSVAFRAFFALY+Q+DRFKN +GLHTNAIYGF+LML H++ RV P+H+LV
Sbjct  3    NKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLV  62

Query  62   AFDAGKTTFRTEMYADYKGGRAKTPDEFREQFPFIRELLDHMGIRHYELAQYEADDIIGT  121
            AFDAGKTTFRTEMYADYK+GRAKTPDEFREQF++IRE+L  +GI  YEL +YEADDIIGT
Sbjct  63   AFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGT  122

Query  122  LDKLAEQDG--FDITIVSGDKDLIQLTDEHTVVEISKKGVAEFEAFTPDYLMEEMGLTPA  179
            LDK+AE+    FD+TIVSGDKDLIQLTDE+TVVEISKKGVAEFE FTP YLME MGLTP 
Sbjct  123  LDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPN  182

Query  180  QFIDLKALMGDKSDNIPGVTKVGEKTGVKLLLEHGSLEGIYENIDGMKTSKMKENLINDK  239
            QFIDLKALMGDKSDNIPGVTK+GEKTG+KLL E GSLEGIYE+IDG KTSKMKENLIND+
Sbjct  183  QFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDR  242

Query  240  EQAFLSKTLATIDTKAPIAIGLEDLVYSGPDVENLGKFYDEMGFKQLKQALNVS-SADVA  298
            +QAFLSKTLATI+T +PI+IGL+D+VY+GPDV +L++FYDEM+F QLK++L    + +  
Sbjct  243  DQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEPV  302

Query  299  EGLDFTIVDQISQDMLSEESIFHIELFGENYHTDNLVGFAWSCGDKLYATDKLELLQDPI  358
              + +  V ++S D++S E IF +E + +NYH + ++GFAW+ G+++YA+  L LL    
Sbjct  303  AVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLATDS  362

Query  359  FKDFLEKTSLRVYDFKKVKVLLQRFGVDLQAPAFDIRLAKYLLSTVEDNEIATIASLYGQ  418
            FK+ ++K ++  YDFK+ KVLL ++G++L AP++D RLA+YLLSTVEDNE++TIA ++ +
Sbjct  363  FKQVFQK-PIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIFTD  421

Query  419  TYLVDDETFYGKGVKKAIPEREKFLEHLACKLVVLVETEPILLEKLSENGQLELLYDMEQ  478
              L +D+T YGKG K+A+P+++ +LEHLA K+ VL+++ + +L+KL+ + QL+L  ++E 
Sbjct  422  ISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNIEL  481

Query  479  PLAFVLAKMEIAGIMVKKETLLEMQAENELVIEKLTQEIYELAGEEFNVNSPKQLGVLLF  538
            PLA VLAKMEI GI V++ TL +M  +N ++IE LTQEIY++AG+EFN+NSPKQLG +LF
Sbjct  482  PLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSILF  541

Query  539  EKLGLPLEYTKKTKTGYSTAVDVLERLAPIAPIVKKILDYRQIAKIQSTYVIGLQDWILA  598
            EK+ LPLE TKKTKTGYSTAVDVLERLAPIAPIV KILDYRQI+K+QSTYVIGLQD ILA
Sbjct  542  EKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYILA  601

Query  599  DGKIHTRYVQDLTQTGRLSSVDPNLQNIPARLEQGRLIRKAFVPEWEDSVLLSSDYSQIE  658
            DGKIHTRYVQDLTQTGRLSSVDPNLQNIP RLEQGRLIRKAF P  ED+VLLSSDYSQIE
Sbjct  602  DGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQIE  661

Query  659  LRVLAHISKDEHLIKAFQEGADIHTSTAMRVFGIERPDDVTANDRRNAKAVNFGVVYGIS  718
            LRVLAHIS DEHLI AF+EGADIHTSTAMRVFGI+++ DVTANDRRNAKAVNFG+VYGIS
Sbjct  662  LRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGIS  721

Query  719  DFGLSNNLGISRKEAKAYIDTYFERFPGIKNYMDEVVREARDKGYVETLFKRRRELPDIN  778
            DFGLSNNLGI+RK++K+YIDTYFER+PGIK YM++VVREA+DKGYVETLFKRRRELPDIN
Sbjct  722  DFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDIN  781

Query  779  SRNFNIRGFAERTAINSPIQGSAADILKIAMIQLDKALVAGGYQTKMLLQVHDEIVLEVP  838
            SRNFN+R+FAERTAINSPIQGSAADILKIAMI+LDKAL AGG+++KMLLQVHDEIVLEVP
Sbjct  782  SRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEVP  841

Query  839  KSELVEMKKLVKQTMEEAIQLSVPLIADENEGATWYEAK  877
            + EL  +KKLVK+TME A++L+VPL  DE+ G +WYEAK
Sbjct  842  NDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

111) polA in NC_021028


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score = 1098 bits (4163),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 635/879 (73%), Positives = 771/879 (88%), Gaps = 4/879 (0%)

Query  2    DKKKLLLIDGSSVAFRAFFALYQQLDRFKNAAGLHTNAIYGFQLMLSHLLERVEPSHILV  61
            +K+KLLLIDGSSVAFRAFFALY+Q+DRFKN +GLHTNAIYGF+LML H++ RV P+H+LV
Sbjct  3    NKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLV  62

Query  62   AFDAGKTTFRTEMYADYKGGRAKTPDEFREQFPFIRELLDHMGIRHYELAQYEADDIIGT  121
            AFDAGKTTFRTEMYADYK+GRAKTPDEFREQF++IRE+L  +GI  YEL +YEADDIIGT
Sbjct  63   AFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGT  122

Query  122  LDKLAEQDG--FDITIVSGDKDLIQLTDEHTVVEISKKGVAEFEAFTPDYLMEEMGLTPA  179
            LDK+AE+    FD+TIVSGDKDLIQLTDE+TVVEISKKGVAEFE FTP YLME MGLTP 
Sbjct  123  LDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPN  182

Query  180  QFIDLKALMGDKSDNIPGVTKVGEKTGVKLLLEHGSLEGIYENIDGMKTSKMKENLINDK  239
            QFIDLKALMGDKSDNIPGVTK+GEKTG+KLL E GSLEGIYE+IDG KTSKMKENLIND+
Sbjct  183  QFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDR  242

Query  240  EQAFLSKTLATIDTKAPIAIGLEDLVYSGPDVENLGKFYDEMGFKQLKQALNVS-SADVA  298
            +QAFLSKTLATI+T +PI+IGL+D+VY+GPDV +L++FYDEM+F QLK++L    + +  
Sbjct  243  DQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEPV  302

Query  299  EGLDFTIVDQISQDMLSEESIFHIELFGENYHTDNLVGFAWSCGDKLYATDKLELLQDPI  358
              + +  V ++S D++S E IF +E + +NYH + ++GFAW+ G+++YA+  L LL    
Sbjct  303  AVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLATDS  362

Query  359  FKDFLEKTSLRVYDFKKVKVLLQRFGVDLQAPAFDIRLAKYLLSTVEDNEIATIASLYGQ  418
            FK+ ++K ++  YDFK+ KVLL ++G++L AP++D RLA+YLLSTVEDNE++TIA ++ +
Sbjct  363  FKQVFQK-PIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIFTD  421

Query  419  TYLVDDETFYGKGVKKAIPEREKFLEHLACKLVVLVETEPILLEKLSENGQLELLYDMEQ  478
              L +D+T YGKG K+A+P+++ +LEHLA K+ VL+++ + +L+KL+ + QL+L  ++E 
Sbjct  422  ISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNIEL  481

Query  479  PLAFVLAKMEIAGIMVKKETLLEMQAENELVIEKLTQEIYELAGEEFNVNSPKQLGVLLF  538
            PLA VLAKMEI GI V++ TL +M  +N ++IE LTQEIY++AG+EFN+NSPKQLG +LF
Sbjct  482  PLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSILF  541

Query  539  EKLGLPLEYTKKTKTGYSTAVDVLERLAPIAPIVKKILDYRQIAKIQSTYVIGLQDWILA  598
            EK+ LPLE TKKTKTGYSTAVDVLERLAPIAPIV KILDYRQI+K+QSTYVIGLQD ILA
Sbjct  542  EKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYILA  601

Query  599  DGKIHTRYVQDLTQTGRLSSVDPNLQNIPARLEQGRLIRKAFVPEWEDSVLLSSDYSQIE  658
            DGKIHTRYVQDLTQTGRLSSVDPNLQNIP RLEQGRLIRKAF P  ED+VLLSSDYSQIE
Sbjct  602  DGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQIE  661

Query  659  LRVLAHISKDEHLIKAFQEGADIHTSTAMRVFGIERPDDVTANDRRNAKAVNFGVVYGIS  718
            LRVLAHIS DEHLI AF+EGADIHTSTAMRVFGI+++ DVTANDRRNAKAVNFG+VYGIS
Sbjct  662  LRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGIS  721

Query  719  DFGLSNNLGISRKEAKAYIDTYFERFPGIKNYMDEVVREARDKGYVETLFKRRRELPDIN  778
            DFGLSNNLGI+RK++K+YIDTYFER+PGIK YM++VVREA+DKGYVETLFKRRRELPDIN
Sbjct  722  DFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDIN  781

Query  779  SRNFNIRGFAERTAINSPIQGSAADILKIAMIQLDKALVAGGYQTKMLLQVHDEIVLEVP  838
            SRNFN+R+FAERTAINSPIQGSAADILKIAMI+LDKAL AGG+++KMLLQVHDEIVLEVP
Sbjct  782  SRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEVP  841

Query  839  KSELVEMKKLVKQTMEEAIQLSVPLIADENEGATWYEAK  877
            + EL  +KKLVK+TME A++L+VPL  DE+ G +WYEAK
Sbjct  842  NDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

112) polA in NC_021026


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score = 1098 bits (4163),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 635/879 (73%), Positives = 771/879 (88%), Gaps = 4/879 (0%)

Query  2    DKKKLLLIDGSSVAFRAFFALYQQLDRFKNAAGLHTNAIYGFQLMLSHLLERVEPSHILV  61
            +K+KLLLIDGSSVAFRAFFALY+Q+DRFKN +GLHTNAIYGF+LML H++ RV P+H+LV
Sbjct  3    NKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLV  62

Query  62   AFDAGKTTFRTEMYADYKGGRAKTPDEFREQFPFIRELLDHMGIRHYELAQYEADDIIGT  121
            AFDAGKTTFRTEMYADYK+GRAKTPDEFREQF++IRE+L  +GI  YEL +YEADDIIGT
Sbjct  63   AFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGT  122

Query  122  LDKLAEQDG--FDITIVSGDKDLIQLTDEHTVVEISKKGVAEFEAFTPDYLMEEMGLTPA  179
            LDK+AE+    FD+TIVSGDKDLIQLTDE+TVVEISKKGVAEFE FTP YLME MGLTP 
Sbjct  123  LDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPN  182

Query  180  QFIDLKALMGDKSDNIPGVTKVGEKTGVKLLLEHGSLEGIYENIDGMKTSKMKENLINDK  239
            QFIDLKALMGDKSDNIPGVTK+GEKTG+KLL E GSLEGIYE+IDG KTSKMKENLIND+
Sbjct  183  QFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDR  242

Query  240  EQAFLSKTLATIDTKAPIAIGLEDLVYSGPDVENLGKFYDEMGFKQLKQALNVS-SADVA  298
            +QAFLSKTLATI+T +PI+IGL+D+VY+GPDV +L++FYDEM+F QLK++L    + +  
Sbjct  243  DQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEPV  302

Query  299  EGLDFTIVDQISQDMLSEESIFHIELFGENYHTDNLVGFAWSCGDKLYATDKLELLQDPI  358
              + +  V ++S D++S E IF +E + +NYH + ++GFAW+ G+++YA+  L LL    
Sbjct  303  AVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLATDS  362

Query  359  FKDFLEKTSLRVYDFKKVKVLLQRFGVDLQAPAFDIRLAKYLLSTVEDNEIATIASLYGQ  418
            FK+ ++K ++  YDFK+ KVLL ++G++L AP++D RLA+YLLSTVEDNE++TIA ++ +
Sbjct  363  FKQVFQK-PIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIFTD  421

Query  419  TYLVDDETFYGKGVKKAIPEREKFLEHLACKLVVLVETEPILLEKLSENGQLELLYDMEQ  478
              L +D+T YGKG K+A+P+++ +LEHLA K+ VL+++ + +L+KL+ + QL+L  ++E 
Sbjct  422  ISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNIEL  481

Query  479  PLAFVLAKMEIAGIMVKKETLLEMQAENELVIEKLTQEIYELAGEEFNVNSPKQLGVLLF  538
            PLA VLAKMEI GI V++ TL +M  +N ++IE LTQEIY++AG+EFN+NSPKQLG +LF
Sbjct  482  PLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSILF  541

Query  539  EKLGLPLEYTKKTKTGYSTAVDVLERLAPIAPIVKKILDYRQIAKIQSTYVIGLQDWILA  598
            EK+ LPLE TKKTKTGYSTAVDVLERLAPIAPIV KILDYRQI+K+QSTYVIGLQD ILA
Sbjct  542  EKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYILA  601

Query  599  DGKIHTRYVQDLTQTGRLSSVDPNLQNIPARLEQGRLIRKAFVPEWEDSVLLSSDYSQIE  658
            DGKIHTRYVQDLTQTGRLSSVDPNLQNIP RLEQGRLIRKAF P  ED+VLLSSDYSQIE
Sbjct  602  DGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQIE  661

Query  659  LRVLAHISKDEHLIKAFQEGADIHTSTAMRVFGIERPDDVTANDRRNAKAVNFGVVYGIS  718
            LRVLAHIS DEHLI AF+EGADIHTSTAMRVFGI+++ DVTANDRRNAKAVNFG+VYGIS
Sbjct  662  LRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGIS  721

Query  719  DFGLSNNLGISRKEAKAYIDTYFERFPGIKNYMDEVVREARDKGYVETLFKRRRELPDIN  778
            DFGLSNNLGI+RK++K+YIDTYFER+PGIK YM++VVREA+DKGYVETLFKRRRELPDIN
Sbjct  722  DFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDIN  781

Query  779  SRNFNIRGFAERTAINSPIQGSAADILKIAMIQLDKALVAGGYQTKMLLQVHDEIVLEVP  838
            SRNFN+R+FAERTAINSPIQGSAADILKIAMI+LDKAL AGG+++KMLLQVHDEIVLEVP
Sbjct  782  SRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEVP  841

Query  839  KSELVEMKKLVKQTMEEAIQLSVPLIADENEGATWYEAK  877
            + EL  +KKLVK+TME A++L+VPL  DE+ G +WYEAK
Sbjct  842  NDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

113) polA in NC_021005


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score = 1098 bits (4163),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 635/879 (73%), Positives = 771/879 (88%), Gaps = 4/879 (0%)

Query  2    DKKKLLLIDGSSVAFRAFFALYQQLDRFKNAAGLHTNAIYGFQLMLSHLLERVEPSHILV  61
            +K+KLLLIDGSSVAFRAFFALY+Q+DRFKN +GLHTNAIYGF+LML H++ RV P+H+LV
Sbjct  3    NKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLV  62

Query  62   AFDAGKTTFRTEMYADYKGGRAKTPDEFREQFPFIRELLDHMGIRHYELAQYEADDIIGT  121
            AFDAGKTTFRTEMYADYK+GRAKTPDEFREQF++IRE+L  +GI  YEL +YEADDIIGT
Sbjct  63   AFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGT  122

Query  122  LDKLAEQDG--FDITIVSGDKDLIQLTDEHTVVEISKKGVAEFEAFTPDYLMEEMGLTPA  179
            LDK+AE+    FD+TIVSGDKDLIQLTDE+TVVEISKKGVAEFE FTP YLME MGLTP 
Sbjct  123  LDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPN  182

Query  180  QFIDLKALMGDKSDNIPGVTKVGEKTGVKLLLEHGSLEGIYENIDGMKTSKMKENLINDK  239
            QFIDLKALMGDKSDNIPGVTK+GEKTG+KLL E GSLEGIYE+IDG KTSKMKENLIND+
Sbjct  183  QFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDR  242

Query  240  EQAFLSKTLATIDTKAPIAIGLEDLVYSGPDVENLGKFYDEMGFKQLKQALNVS-SADVA  298
            +QAFLSKTLATI+T +PI+IGL+D+VY+GPDV +L++FYDEM+F QLK++L    + +  
Sbjct  243  DQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEPV  302

Query  299  EGLDFTIVDQISQDMLSEESIFHIELFGENYHTDNLVGFAWSCGDKLYATDKLELLQDPI  358
              + +  V ++S D++S E IF +E + +NYH + ++GFAW+ G+++YA+  L LL    
Sbjct  303  AVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLATDS  362

Query  359  FKDFLEKTSLRVYDFKKVKVLLQRFGVDLQAPAFDIRLAKYLLSTVEDNEIATIASLYGQ  418
            FK+ ++K ++  YDFK+ KVLL ++G++L AP++D RLA+YLLSTVEDNE++TIA ++ +
Sbjct  363  FKQVFQK-PIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIFTD  421

Query  419  TYLVDDETFYGKGVKKAIPEREKFLEHLACKLVVLVETEPILLEKLSENGQLELLYDMEQ  478
              L +D+T YGKG K+A+P+++ +LEHLA K+ VL+++ + +L+KL+ + QL+L  ++E 
Sbjct  422  ISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNIEL  481

Query  479  PLAFVLAKMEIAGIMVKKETLLEMQAENELVIEKLTQEIYELAGEEFNVNSPKQLGVLLF  538
            PLA VLAKMEI GI V++ TL +M  +N ++IE LTQEIY++AG+EFN+NSPKQLG +LF
Sbjct  482  PLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSILF  541

Query  539  EKLGLPLEYTKKTKTGYSTAVDVLERLAPIAPIVKKILDYRQIAKIQSTYVIGLQDWILA  598
            EK+ LPLE TKKTKTGYSTAVDVLERLAPIAPIV KILDYRQI+K+QSTYVIGLQD ILA
Sbjct  542  EKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYILA  601

Query  599  DGKIHTRYVQDLTQTGRLSSVDPNLQNIPARLEQGRLIRKAFVPEWEDSVLLSSDYSQIE  658
            DGKIHTRYVQDLTQTGRLSSVDPNLQNIP RLEQGRLIRKAF P  ED+VLLSSDYSQIE
Sbjct  602  DGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQIE  661

Query  659  LRVLAHISKDEHLIKAFQEGADIHTSTAMRVFGIERPDDVTANDRRNAKAVNFGVVYGIS  718
            LRVLAHIS DEHLI AF+EGADIHTSTAMRVFGI+++ DVTANDRRNAKAVNFG+VYGIS
Sbjct  662  LRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGIS  721

Query  719  DFGLSNNLGISRKEAKAYIDTYFERFPGIKNYMDEVVREARDKGYVETLFKRRRELPDIN  778
            DFGLSNNLGI+RK++K+YIDTYFER+PGIK YM++VVREA+DKGYVETLFKRRRELPDIN
Sbjct  722  DFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDIN  781

Query  779  SRNFNIRGFAERTAINSPIQGSAADILKIAMIQLDKALVAGGYQTKMLLQVHDEIVLEVP  838
            SRNFN+R+FAERTAINSPIQGSAADILKIAMI+LDKAL AGG+++KMLLQVHDEIVLEVP
Sbjct  782  SRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEVP  841

Query  839  KSELVEMKKLVKQTMEEAIQLSVPLIADENEGATWYEAK  877
            + EL  +KKLVK+TME A++L+VPL  DE+ G +WYEAK
Sbjct  842  NDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

114) SPJ_0056 in NC_012466


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score = 1098 bits (4162),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 632/879 (72%), Positives = 771/879 (88%), Gaps = 4/879 (0%)

Query  2    DKKKLLLIDGSSVAFRAFFALYQQLDRFKNAAGLHTNAIYGFQLMLSHLLERVEPSHILV  61
            +K+KLLLIDGSSVAFRAFFALY+Q+DRFKN +GLHTNAIYGF+LML H++ RV P+H+LV
Sbjct  3    NKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLV  62

Query  62   AFDAGKTTFRTEMYADYKGGRAKTPDEFREQFPFIRELLDHMGIRHYELAQYEADDIIGT  121
            AFDAGKTTFRTEMYADYK+GRAKTPDEFREQF++IRE+L  +GI  YEL +YEADDIIGT
Sbjct  63   AFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGT  122

Query  122  LDKLAEQDG--FDITIVSGDKDLIQLTDEHTVVEISKKGVAEFEAFTPDYLMEEMGLTPA  179
            LDK+AE+    FD+TIVSGDKDLIQLTDE+TVVEISKKGVAEFE FTP YLME MGLTP 
Sbjct  123  LDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPN  182

Query  180  QFIDLKALMGDKSDNIPGVTKVGEKTGIKLLLEYGSLEGIYENIDGMKTSKMKENLINDK  239
            QFIDLKALMGDKSDNIPGVTK+GEKTG+KLL E+GSLEGIYE+IDG KTSKMKENLIND+
Sbjct  183  QFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDR  242

Query  240  EQAFLSKTLATIDTKAPIAIGLEDLVYSGPDVENLGKFYDEMGFKQLKQALNVS-SADVA  298
            +QAFLSKTLATI+T +PI+IGL+D+VY+GPDV +L++FYDEM+F QLK++L    + +  
Sbjct  243  DQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEPV  302

Query  299  KGLDFTIVDQISQDMLSEESIFHFELFGENYHTDNLVGFAWSCEDKLYATDKLELLQDPI  358
              + +  V ++S D++S E IF FE + +NYH + ++GFAW+  +++YA+  L LL    
Sbjct  303  AVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLATDS  362

Query  359  FKDFLEKTSLRVYDFKKVKVLLQRFGVDLQAPAFDIRLAKYLLSTVEDNEIATIASLYGQ  418
            FK+ ++K ++  YDFK+ KVLL ++G++L AP++D RLA+YLLSTVEDNE++TIA ++ +
Sbjct  363  FKQVFQK-PIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIFTD  421

Query  419  TYLVDDETFYGKGVKKAIPEREKFLEHLACKLAVLVETEPILLEKLSENGQLELLYDMEQ  478
              L +D+T YGKG K+A+P+++ +LEHLA K+ VL+++ + +L+KL+ + QL+L  ++E 
Sbjct  422  ISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNIEL  481

Query  479  PLAFVLAKMEIAGIVVKKETLLEMQAENELVIEKLTQEIYELAGEEFNVNSPKQLGVLLF  538
            PLA VLAKMEI GI V++ TL +M  +N ++IE LTQEIY++AG+EFN+NSPKQLG +LF
Sbjct  482  PLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSILF  541

Query  539  EKLGLPLEYTKKTKTGYSTAVDVLERLAPIAPIVKKILDYRQIAKIQSTYVIGLQDWILA  598
            EK+ LPLE TKKTKTGYSTAVDVLERLAPIAPIV KILDYRQI+K+QSTYVIGLQD ILA
Sbjct  542  EKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYILA  601

Query  599  DGKIHTRYMQDLTQTGRLSSVDPNLQNIPARLEQGRLIRKAFVPEWEDSVLLSSDYSQIE  658
            DGKIHTRY+QDLTQTGRLSSVDPNLQNIP RLEQGRLIRKAF P  ED+VLLSSDYSQIE
Sbjct  602  DGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQIE  661

Query  659  LRVLAHISKDEHLIKAFQEGADIHTSTAMRVFGIERPDNVTANDRRNAKAVNFGVVYGIS  718
            LRVLAHIS DEHLI AF+EGADIHTSTAMRVFGI+++ +VTANDRRNAKAVNFG+VYGIS
Sbjct  662  LRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGIS  721

Query  719  DFGLSNNLGISRKEAKAYIDTYFERFPDIKNYMDEVVREARDKGYVETLFKRRRELPDIN  778
            DFGLSNNLGI+RK++K+YIDTYFER+P+IK YM++VVREA+DKGYVETLFKRRRELPDIN
Sbjct  722  DFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDIN  781

Query  779  SRNFNIRGFAERTAINSPIQGSAADILKIAMIQLDKALVAGGYQTKMLLQVHDEIVLEVP  838
            SRNFN+R+FAERTAINSPIQGSAADILKIAMI+LDKAL AGG+++KMLLQVHDEIVLEVP
Sbjct  782  SRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEVP  841

Query  839  KSELVEMKKLVKQTMEEAIQLSVPLIADENEGATWYEAK  877
            + EL  +KKLVK+TME A++L+VPL  DE+ G +WYEAK
Sbjct  842  NDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

115) SP670_0108 in NC_014498


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score = 1097 bits (4161),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 633/879 (73%), Positives = 771/879 (88%), Gaps = 4/879 (0%)

Query  2    DKKKLLLIDGSSVAFRAFFALYQQLDRFKNAAGLHTNAIYGFQLMLSHLLERVEPSHILV  61
            +K+KLLLIDGSSVAFRAFFALY+Q+DRFKN +GLHTNAIYGF+LML H++ RV P+H+LV
Sbjct  3    NKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLV  62

Query  62   AFDAGKTTFRTEMYADYKGGRAKTPDEFREQFPFIRELLDHMGIRHYELAQYEADDIIGT  121
            AFDAGKTTFRTEMYADYK+GRAKTPDEFREQF++IRE+L  +GI  YEL +YEADDIIGT
Sbjct  63   AFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGT  122

Query  122  LDKLAEQDG--FDITIVSGDKDLIQLTDEHTVVEISKKGVAEFEAFTPDYLMEEMGLTPA  179
            LDK+AE+    FD+TIVSGDKDLIQLTDE+TVVEISKKGVAEFE FTP YLME MGLTP 
Sbjct  123  LDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPN  182

Query  180  QFIDLKALMGDKSDNIPGVTKVGEKTGIKLLLEHGSLEGIYENIDGMKTSKMKENLINDK  239
            QFIDLKALMGDKSDNIPGVTK+GEKTG+KLL E GSLEGIYE+IDG KTSKMKENLIND+
Sbjct  183  QFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDR  242

Query  240  EQAFLSKTLATIDTKAPIAIGLEDLVYSGPDVENLGKFYDEMGFKQLKQALNVS-SADVA  298
            +QAFLSKTLATI+T +PI+IGL+D+VY+GPDV +L++FYDEM+F QLK++L    + +  
Sbjct  243  DQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEPV  302

Query  299  KGLDFTIVDQISQDMLSEESIFHFELFGENYHTDNLVGFAWSCGDKLYATDKLELLQDPI  358
              + +  V ++S D++S E IF FE + +NYH + ++GFAW+ G+++YA+  L LL    
Sbjct  303  AVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLATDS  362

Query  359  FKDFLEKTSLRVYDFKKVKVLLQRFGVDLQAPAFDIRLAKYLLSTVEDNEIATIASLYGQ  418
            FK+ ++K ++  YDFK+ KVLL ++G++L AP++D RLA+YLLSTVEDNE++TIA ++ +
Sbjct  363  FKQVFQK-PIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIFTD  421

Query  419  TYLVDDETFYGKGVKKAIPEREKFLEHLACKLAVLVETEPILLEKLSENGQLELLYDMEQ  478
              L +D+T YGKG K+A+P+++ +LEHLA K+ VL+++ + +L+KL+ + QL+L  ++E 
Sbjct  422  ISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNIEL  481

Query  479  PLAFVLAKMEIAGIVVKKETLLEMQAENELVIEKLTQEIYELAGEEFNVNSPKQLGVLLF  538
            PLA VLAKMEI GI V++ TL +M  +N ++IE LTQEIY++AG+EFN+NSPKQLG +LF
Sbjct  482  PLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSILF  541

Query  539  EKLGLPLEYTKKTKTGYSTAVDVLERLAPIAPIVKKILDYRQIAKIQSTYVIGLQDWILA  598
            EK+ LPLE TKKTKTGYSTAVDVLERLAPIAPIV KILDYRQI+K+QSTYVIGLQD ILA
Sbjct  542  EKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYILA  601

Query  599  DGKIHTRYMQDLTQTGRLSSVDPNLQNIPARLEQGRLIRKAFVPEWEDSVLLSSDYSQIE  658
            DGKIHTRY+QDLTQTGRLSSVDPNLQNIP RLEQGRLIRKAF P  ED+VLLSSDYSQIE
Sbjct  602  DGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQIE  661

Query  659  LRVLAHISKDEHLIKAFQEGADIHTSTAMRVFGIERPDNVTANDRRNAKAVNFGVVYGIS  718
            LRVLAHIS DEHLI AF+EGADIHTSTAMRVFGI+++ +VTANDRRNAKAVNFG+VYGIS
Sbjct  662  LRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGIS  721

Query  719  DFGLSNNLGISRKEAKAYIDTYFERFPGIKNYMDEVVREARDKSYVETLFKRRRELPDIN  778
            DFGLSNNLGI+RK++K+YIDTYFER+PGIK YM++VVREA+DK+YVETLFKRRRELPDIN
Sbjct  722  DFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDIN  781

Query  779  SRNFNIRGFAERTAINSPIQGSAADILKIAMIQLDKALVAGGYQTKMLLQVHDEIVLEVP  838
            SRNFN+R+FAERTAINSPIQGSAADILKIAMI+LDKAL AGG+++KMLLQVHDEIVLEVP
Sbjct  782  SRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEVP  841

Query  839  KSELVEMKKLVKQTMEEAIQLSVPLIADENEGATWYEAK  877
            + EL  +KKLVK+TME A++L+VPL  DE+ G +WYEAK
Sbjct  842  NDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

116) polA in NC_002662


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score = 1034 bits (3921),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 613/886 (70%), Positives = 751/886 (85%), Gaps = 15/886 (1%)

Query  1    MENKDRLLLIDGSSVAFRAFFALYNQIDRFKAPNGLHTNAIFAFHTMLSSLMERIEPTHV  60
            MENK++LLLIDGSSVAFRAFFALYNQIDRFK  +GLHTNAI++FH ML  +M R+ PTHV
Sbjct  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60

Query  61   LIAFDAGKTTFRTEMFADYKGGRSKTPDEFREQLPFIKEMIEKLGIRHYELANYEADDII  120
            L+AFDAGKTTFRTEM+ADYK+GR+KTPDEFREQ+++I+EM+  LGI  YEL +YEADDII
Sbjct  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120

Query  121  GTLDKMAEAPNVNFDVTIVTGDKDMIQLVDGNTRVEISKKGVAEFEEFTPDYLLEKMGLT  180
            GTLDKMAE  +V FDVTIV+GDKD+IQL D NT VEISKKGVAEFEEFTP YL+EKMGLT
Sbjct  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180

Query  181  PAQFIDLKALMGDSSDNYPGVTKVGEKTGLKLLQEFGSLENLYENVDSLKASKMKENLIA  240
            P QFIDLKALMGD SDN PGVTK+GEKTGLKLL+EFGSLE +YE++D++K+SKMKENLI 
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  241  DKEMAFLSQQLATINTKAPIEIGLDDTLLKGKKVDELSQFYDEMGFAQFKSKLLAEAGGE  300
            D++ AFLS+ LATINT +PI IGLDD + +G  V  LSQFYDEM+F Q+K  L    +++
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGL----ASQ  296

Query  301  VTDEKVVDEIDFEIVTDGSISEKVNADDFFYLETLGENYHREQIVAFAWGNAEKIYVSKN  360
            + +E  V  I ++ VT+ S ++  +A+D+FY+ETL +NYHRE I++FAWG++E+IY S +
Sbjct  297  MPQEP-VAVISYQEVTNVS-ADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTD  354

Query  361  IDLLTKMKF------PENTYDFKKNRVLLSHLDIELPLVKFDAMLAKYLISTTEDNKIST  414
            + LL+   F      P  TYDFK+++VLLSHL+IEL    +DA LA+YL+ST EDN +ST
Sbjct  355  LSLLATDSFKQVFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELST  414

Query  415  IARLFNSGHLATDEEIFGKGTKIALPDDAVLFEHLARKIKVLALAKEKMMAELLENEQEH  474
            IAR+F    L  D+ ++GKG+K A+PD  VL+EHLARK+KVL  +K +M+  L  +EQ +
Sbjct  415  IARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLD  474

Query  475  LLSDMELPLAEVLAKMEITGIAVSQNTLEEIGAENEEKLASLTREIYDLAGEEFNINSPK  534
            L  ++ELPLA+VLAKMEI GI V++ TL++++ +N   + +LT+EIYD+AG+EFNINSPK
Sbjct  475  LYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPK  534

Query  535  QLGVILFEKLQLP--VGKKTKTGYSTAVDVLEDLAALSPVVAKILEYRQINKVQSTYVKG  592
            QLG ILFEK+QLP  + KKTKTGYSTAVDVLE LA+++P+VAKIL+YRQI K+QSTYV G
Sbjct  535  QLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIG  594

Query  593  LIPQIADDGKIHTRYVQDLTQTGRLSSVDPNLQNIPVRLEEGRKIRKAFVPSKDsll-ls  651
            L   I  DGKIHTRYVQDLTQTGRLSSVDPNLQNIP+RLE+GR IRKAF PS +  + LS
Sbjct  595  LQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLS  654

Query  652  sDYSQIELRVLAHISGDEHLIDAFKHGADIHTSTAMRVFGIEKAEDVTANDRRNAKAVNF  711
            SDYSQIELRVLAHISGDEHLI AF++GADIHTSTAMRVFGI+KA DVTANDRRNAKAVNF
Sbjct  655  SDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNF  714

Query  712  GVVYGISDFGLARNLGITRKDAKNYIETYFERYPGIKTYMENIVREARDKGFVETMSHRR  771
            G+VYGISDFGL+ NLGITRK++K+YI+TYFERYPGIK+YMEN+VREA+DKG+VET+  RR
Sbjct  715  GIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRR  774

Query  772  RKIPDINARNFNVRGFAERTAINSPIQGSAADILKIAMINLDKALSARDFKSKLLLQVHD  831
            R +PDIN+RNFNVR+FAERTAINSPIQGSAADILKIAMINLDKAL A +F++K+LLQVHD
Sbjct  775  RELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHD  834

Query  832  EIILDVPLEELDEIKVLVKQTMEEAIELAVPLKVDENTGKTWYEAK  877
            EI+L+VP +EL  IK LVK+TME A++LAVPL VDE+TG++WYEAK
Sbjct  835  EIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

117) polA in NC_017486


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score = 1033 bits (3916),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 613/886 (70%), Positives = 750/886 (85%), Gaps = 15/886 (1%)

Query  1    MENKDRLLLIDGSSVAFRAFFALYNQIDRFKAPNGLHTNAIFAFHTMLSSLMERIEPTHV  60
            MENK++LLLIDGSSVAFRAFFALYNQIDRFK  +GLHTNAI++FH ML  +M R+ PTHV
Sbjct  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60

Query  61   LIAFDAGKTTFRTEMFADYKGGRSKTPDEFREQLPFIKEMIEKLGIRHYELANYEADDII  120
            L+AFDAGKTTFRTEM+ADYK+GR+KTPDEFREQ+++I+EM+  LGI  YEL +YEADDII
Sbjct  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120

Query  121  GTLDKMAEAPIVNFDVTIVTGDKDMIQLVDGNTRVEISKKGVAEFEEFTPDYLLEKMGLT  180
            GTLDKMAE   V FDVTIV+GDKD+IQL D NT VEISKKGVAEFEEFTP YL+EKMGLT
Sbjct  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180

Query  181  PAQFIDLKALMGDSSDNYPGVTKVGEKTGLKLLQEFGSLENLYENVDSLKASKMKENLIA  240
            P QFIDLKALMGD SDN PGVTK+GEKTGLKLL+EFGSLE +YE++D++K+SKMKENLI 
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  241  DKEMAFLSQQLATINTKAPIEIGLDDTLLKGKKVDELSQFYDEMGFAQFKSKLLAEAGGE  300
            D++ AFLS+ LATINT +PI IGLDD + +G  V  LSQFYDEM+F Q+K  L    +++
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGL----ASQ  296

Query  301  VTDEKVVDEIDFEIVTDGSISEKVNADDFFYLETLGENYHREQIVAFAWGNAEKIYVSKN  360
            + +E  V  I ++ VT+ S ++  +A+D+FY+ETL +NYHRE I++FAWG++E+IY S +
Sbjct  297  MPQEP-VAVISYQEVTNVS-ADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTD  354

Query  361  IDLLTKMKF------PENTYDFKKNRVLLSHLDIELPLVKFDAMLAKYLISTTEDNKIST  414
            + LL+   F      P  TYDFK+++VLLSHL+IEL    +DA LA+YL+ST EDN +ST
Sbjct  355  LSLLATDSFKQVFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELST  414

Query  415  IARLFNSGHLATDEEIFGKGTKIALPDDAVLFEHLARKIKVLALAKEKMMAELLENEQEH  474
            IAR+F    L  D+ ++GKG+K A+PD  VL+EHLARK+KVL  +K +M+  L  +EQ +
Sbjct  415  IARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLD  474

Query  475  LLSDMELPLAEVLAKMEITGIAVSQNTLEEIGAENEEKLASLTREIYDLAGEEFNINSPK  534
            L  ++ELPLA+VLAKMEI GI V++ TL++++ +N   + +LT+EIYD+AG+EFNINSPK
Sbjct  475  LYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPK  534

Query  535  QLGVILFEKLQLP--VGKKTKTGYSTAVDVLEDLAALSPVVAKILEYRQINKVQSTYVKG  592
            QLG ILFEK+QLP  + KKTKTGYSTAVDVLE LA+++P+VAKIL+YRQI K+QSTYV G
Sbjct  535  QLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIG  594

Query  593  LIPQIADDGKIHTRYVQDLTQTGRLSSVDPNLQNIPVRLEEGRKIRKAFVPSKDsll-ls  651
            L   I  DGKIHTRYVQDLTQTGRLSSVDPNLQNIP+RLE+GR IRKAF PS +  + LS
Sbjct  595  LQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLS  654

Query  652  sDYSQIELRVLAHISGDEHLIDAFKHGADIHTSTAMRVFGIEKAEDVTANDRRNAKAVNF  711
            SDYSQIELRVLAHISGDEHLI AF++GADIHTSTAMRVFGI+KA DVTANDRRNAKAVNF
Sbjct  655  SDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNF  714

Query  712  GVVYGISDFGLARNLGITRKDAKNYIETYFERYPGIKTYMENIVREARDKGFVETMSHRR  771
            G+VYGISDFGL+ NLGITRK++K+YI+TYFERYPGIK+YMEN+VREA+DKG+VET+  RR
Sbjct  715  GIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRR  774

Query  772  RKIPDINARNFNVRGFAERTAINSPIQGSAADILKIAMINLDKALSARDFKSKLLLQVHD  831
            R +PDIN+RNFNVR+FAERTAINSPIQGSAADILKIAMINLDKAL A +F++K+LLQVHD
Sbjct  775  RELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHD  834

Query  832  EIILDVPLEELDEIKALVKQTMEEAIELAVPLKVDENTGKTWYEAK  877
            EI+L+VP +EL  IK LVK+TME A++LAVPL VDE+TG++WYEAK
Sbjct  835  EIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

118) polA in NC_020450


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score = 1026 bits (3888),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 613/886 (70%), Positives = 751/886 (85%), Gaps = 15/886 (1%)

Query  8    MENKDRLLLIDGSSVAFRAFFALYNQIDRFKAPNGLHTNAIFAFHTMLSSLMERIEPTHV  67
            MENK++LLLIDGSSVAFRAFFALYNQIDRFK  +GLHTNAI++FH ML  +M R+ PTHV
Sbjct  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60

Query  68   LIAFDAGKTTFRTEMFADYKGGRSKTPDEFREQLPFIKEMIEKLGIRHYELANYEADDII  127
            L+AFDAGKTTFRTEM+ADYK+GR+KTPDEFREQ+++I+EM+  LGI  YEL +YEADDII
Sbjct  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120

Query  128  GTLDKMAEAPDVNFDVTIVTGDKDMIQLVDGNTRVEISKKGVAEFEEFTPDYLLEKMGLT  187
            GTLDKMAE  +V FDVTIV+GDKD+IQL D NT VEISKKGVAEFEEFTP YL+EKMGLT
Sbjct  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180

Query  188  PAQFIDLKALMGDSSDNYPGVTKVGEKTGLKLLQEFGSLENLYENVDSLKASKMKENLIA  247
            P QFIDLKALMGD SDN PGVTK+GEKTGLKLL+EFGSLE +YE++D++K+SKMKENLI 
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  248  DKEMAFLSQQLATINTKAPIEIGlddtllkdkkVDELSQFYDEMGFAQFKSKLLTEAGGE  307
            D++ AFLS+ LATINT +PI IGLDD + ++  V  LSQFYDEM+F Q+K  L    +++
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGL----ASQ  296

Query  308  VTDEKVVDEIDFEIVTDGSISEKVNADDFFYLETLGENYHREQIVAFAWGNAEKIYVSKN  367
            + +E  V  I ++ VT+ S ++  +A+D+FY+ETL +NYHRE I++FAWG++E+IY S +
Sbjct  297  MPQEP-VAVISYQEVTNVS-ADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTD  354

Query  368  IDLLTKMKF------PENTYDFKKNRVLLSHLDIELPLVKFDAMLAKYLISTTEDNKIST  421
            + LL+   F      P  TYDFK+++VLLSHL+IEL    +DA LA+YL+ST EDN +ST
Sbjct  355  LSLLATDSFKQVFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELST  414

Query  422  IARLFNSGHLATDEEVFGKGTKIALPDDAVLFEHLARKIKVLALAKEKMMAELLENEQEH  481
            IAR+F    L  D+ V+GKG+K A+PD  VL+EHLARK+KVL  +K +M+  L  +EQ +
Sbjct  415  IARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLD  474

Query  482  LLADMELPLAEVLAKMEITGIAVSQNTLEEIGAENEEKLASLTREIYDLAGEEFNINSPK  541
            L  ++ELPLA+VLAKMEI GI V++ TL++++ +N   + +LT+EIYD+AG+EFNINSPK
Sbjct  475  LYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPK  534

Query  542  QLGVILFEKLQLP--VGKKTKTGYSTAVDVLEDLAALSPVVAKILEYRQINKVQSTYVKG  599
            QLG ILFEK+QLP  + KKTKTGYSTAVDVLE LA+++P+VAKIL+YRQI K+QSTYV G
Sbjct  535  QLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIG  594

Query  600  LIPQIADDGKIHTRYVQDLTQTGRLSSVDPNLQNIPVRLEEGRKIRKAFVPSKDsll-ls  658
            L   I  DGKIHTRYVQDLTQTGRLSSVDPNLQNIP+RLE+GR IRKAF PS +  + LS
Sbjct  595  LQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLS  654

Query  659  sDYSQIELRVLAHISGDEHLIDAFKHGADIHTSTAMRVFGIEKAEDVTANDRRNAKAVNF  718
            SDYSQIELRVLAHISGDEHLI AF++GADIHTSTAMRVFGI+KA DVTANDRRNAKAVNF
Sbjct  655  SDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNF  714

Query  719  GVVYGISDFGLARNLGITRKDAKNYIETYFERYPGIKTYMENIVREARDKGFVETMSHRR  778
            G+VYGISDFGL+ NLGITRK++K+YI+TYFERYPGIK+YMEN+VREA+DKG+VET+  RR
Sbjct  715  GIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRR  774

Query  779  RKIPDINARNFNVRGFAERTAINSPIQGSAADILKIAMINLDKALSARDFKSKLLLQVHD  838
            R +PDIN+RNFNVR+FAERTAINSPIQGSAADILKIAMINLDKAL A +F++K+LLQVHD
Sbjct  775  RELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHD  834

Query  839  EIILDVPLEELDEIKALVKQTMEEAIELAVPLKVDENTGKTWYEAK  884
            EI+L+VP +EL  IK LVK+TME A++LAVPL VDE+TG++WYEAK
Sbjct  835  EIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

119) polA in NC_013656


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score = 1019 bits (3864),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 608/886 (69%), Positives = 748/886 (85%), Gaps = 15/886 (1%)

Query  1    MENNNRLLLIDGSSVAFRAFFALYNQIARFKAPNGLHTNAIFAFHTMLSSLMERIEPTHV  60
            MEN+N+LLLIDGSSVAFRAFFALYNQI RFK  +GLHTNAI++FH ML  +M R+ PTHV
Sbjct  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60

Query  61   LIAFDAGKTTFRTEMFADYKGGRSKTPDEFREQLPFIKEMIEKLGIRHYELANYEADDII  120
            L+AFDAGKTTFRTEM+ADYK+GR+KTPDEFREQ+++I+EM+  LGI  YEL +YEADDII
Sbjct  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120

Query  121  GTLDKMAEAPNVNFDVTIVTGDKDMIQLVDGNTRVEISKKGVAEFEEFTPDYLLEKMGLT  180
            GTLDKMAE  +V FDVTIV+GDKD+IQL D NT VEISKKGVAEFEEFTP YL+EKMGLT
Sbjct  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180

Query  181  PAQFIDLKALMGDSSDNYPGVTKVGEKTGLKLLQEFGSLENLYENVDSLKASKMKENLIA  240
            P QFIDLKALMGD SDN PGVTK+GEKTGLKLL+EFGSLE +YE++D++K+SKMKENLI 
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  241  DKEMAFLSQQLATINIKAPIEIGlddtllkdkkIDELSQFYDEMGFAQFKSKLLAEAGGE  300
            D++ AFLS+ LATIN  +PI IGLDD + ++  +  LSQFYDEM+F Q+K  L    +++
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGL----ASQ  296

Query  301  VTDEKVVDEIDFEIVNDGSISEKVNADDFFYLETLGENYHREQIVAFAWGNAEKIYVSKN  360
            + +E  V  I ++ V + S ++  +A+D+FY+ETL +NYHRE I++FAWG++E+IY S +
Sbjct  297  MPQEP-VAVISYQEVTNVS-ADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTD  354

Query  361  IDLLTKMKF------PENTYDFKKNRVLLSHLDIELPLVKFDAMLAKYLISTTEDNKIST  414
            + LL+   F      P  TYDFK+++VLLSHL+IEL    +DA LA+YL+ST EDN +ST
Sbjct  355  LSLLATDSFKQVFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELST  414

Query  415  IARLFNSGHLATDEEIFGKGTKIALPDDAVLFEHLARKIKVLALAKEKMMAELLENEQEH  474
            IAR+F    L  D+ ++GKG+K A+PD  VL+EHLARK+KVL  +K +M+  L  +EQ +
Sbjct  415  IARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLD  474

Query  475  LLSDMELPLAEVLAKMEITGIAVSQNTLEEIGAENEEKLASLTREIYDLAGEEFNINSPK  534
            L  ++ELPLA+VLAKMEI GI V++ TL++++ +N   + +LT+EIYD+AG+EFNINSPK
Sbjct  475  LYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPK  534

Query  535  QLGVILFEKLQLP--VGKKTKTGYSTAVDVLEDLAALSPVVAKILEYRQINKVQSTYVKG  592
            QLG ILFEK+QLP  + KKTKTGYSTAVDVLE LA+++P+VAKIL+YRQI K+QSTYV G
Sbjct  535  QLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIG  594

Query  593  LIPQIADDGKIHTRYVQDLTQTGRLSSVDPNLQNIPVRLEEGRKIRKAFVPSKDsll-ls  651
            L   I  DGKIHTRYVQDLTQTGRLSSVDPNLQNIP+RLE+GR IRKAF PS +  + LS
Sbjct  595  LQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLS  654

Query  652  sDYSQIELRVLAHISGDEHLIDAFKHGADIHTSTAMRVFGIEKAEDVTANDRRNAKAVNF  711
            SDYSQIELRVLAHISGDEHLI AF++GADIHTSTAMRVFGI+KA DVTANDRRNAKAVNF
Sbjct  655  SDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNF  714

Query  712  GVVYGISDFGLARNLGITRKDAKNYIETYFERYPGIKTYMENIVREARDKGFVETMSHRR  771
            G+VYGISDFGL+ NLGITRK++K+YI+TYFERYPGIK+YMEN+VREA+DKG+VET+  RR
Sbjct  715  GIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRR  774

Query  772  RKIPDINARNFNVRGFAERTAINSPIQGSAADILKIAMINLDKALSARDFKSKLLLQVHD  831
            R +PDIN+RNFNVR+FAERTAINSPIQGSAADILKIAMINLDKAL A +F++K+LLQVHD
Sbjct  775  RELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHD  834

Query  832  EIILDVPLEELDEIKALVKQTMEEAIELAVPLKVDENTGKTWYEAK  877
            EI+L+VP +EL  IK LVK+TME A++LAVPL VDE+TG++WYEAK
Sbjct  835  EIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

120) polA in NC_022369


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score = 1017 bits (3853),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 599/886 (68%), Positives = 749/886 (85%), Gaps = 15/886 (1%)

Query  1    MEDKNRLLLIDGSSVAFRAFFALYNQLDRFKAPNGLHTNAIFAFHTMLSSLMERIQPTHV  60
            ME+KN+LLLIDGSSVAFRAFFALYNQ+DRFK  +GLHTNAI++FH ML  +M R++PTHV
Sbjct  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60

Query  61   LIAFDAGKTTFRTEMFADYKGGRSKTPDEFREQLPFIKEMIEKLGIRHYELANYEADDII  120
            L+AFDAGKTTFRTEM+ADYK+GR+KTPDEFREQ+++I+EM+  LGI  YEL +YEADDII
Sbjct  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120

Query  121  GTLDKMAEAPDVNFDVTIVTGDKDMIQLVDGNTRVEISKKGVAEFEEFTPDYLLEKMGLT  180
            GTLDKMAE  +V FDVTIV+GDKD+IQL D NT VEISKKGVAEFEEFTP YL+EKMGLT
Sbjct  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180

Query  181  PSQFIDLKALMGDSSDNYPGVTKVGEKTGLKLLQEFGSLENLYENVETLKASKMKDNLIA  240
            P+QFIDLKALMGD SDN PGVTK+GEKTGLKLL+EFGSLE +YE+++ +K+SKMK+NLI 
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  241  DKEMAFLSQQLATINTKAPLEIGLEDTLLKEKNVAELGQFYDEMGFSQFKSKLLADGGGE  300
            D++ AFLS+ LATINT +P+ IGL+D + +  +VA L+QFYDEM+F Q+K  L    +++
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGL----ASQ  296

Query  301  VTDETVSEEIKFEIVTDKSSVASVNADDFFYLETLGENYHREQIVAFAWGNSEKIYVSKN  360
            + +E V+  I ++ VT+  S    +A+D+FY+ETL +NYHRE I++FAWG++E+IY S +
Sbjct  297  MPQEPVA-VISYQEVTN-VSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTD  354

Query  361  LDLLTEMKF------PENTYDFKKNRVLLSHLSIELPLVKFDAMLAKYLISTTEDNKIST  414
            L LL+   F      P  TYDFK+++VLLSHL+IEL    +DA LA+YL+ST EDN +ST
Sbjct  355  LSLLATDSFKQVFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELST  414

Query  415  IARLFDVGHLVTDEEIFGKGTKLALPDDEILFDHLARKIRVLARAKEKMMAELIENEQEH  474
            IAR+F    L  D+ ++GKG+K A+PD ++L++HLARK++VL  +K +M+  L  +EQ +
Sbjct  415  IARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLD  474

Query  475  LLSDMELPLAEVLAKMEITGISVSQNTLEEIGAENEEKLASLTREIYDLAGEEFNINSPK  534
            L  ++ELPLA+VLAKMEI GI V++ TL++++ +N   + +LT+EIYD+AG+EFNINSPK
Sbjct  475  LYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPK  534

Query  535  QLGVILFEKLQLP--VGKKTKTGYSTAVDVLEDLAALSPVVAKILEYRQINKVQSTYVKG  592
            QLG ILFEK+QLP  + KKTKTGYSTAVDVLE LA+++P+VAKIL+YRQI K+QSTYV G
Sbjct  535  QLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIG  594

Query  593  LIPQIADDGKIHTRYVQDLTQTGRLSSVDPNLQNIPVRLEEGRKIRKAFVPsqdslllss  652
            L   I  DGKIHTRYVQDLTQTGRLSSVDPNLQNIP+RLE+GR IRKAF PS++  +L S
Sbjct  595  LQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLS  654

Query  653  dy-sqIELRVLAHISADEHLIDAFKHGADIHTSTAMRVFGIEKAEDVTANDRRNAKAVNF  711
               SQIELRVLAHIS+DEHLI AF++GADIHTSTAMRVFGI+KA DVTANDRRNAKAVNF
Sbjct  655  SDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNF  714

Query  712  GVVYGISDFGLARNLGITRKDAKNYIETYFERYPGIKTYMENIVREARDKGFVETMSHRR  771
            G+VYGISDFGL+ NLGITRK++K+YI+TYFERYPGIK+YMEN+VREA+DKG+VET+  RR
Sbjct  715  GIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRR  774

Query  772  RKIPDINARNFNVRGFAERTAINSPIQGSAADILKIAMINLDKALTERQLKSKLLLQVHD  831
            R +PDIN+RNFNVR+FAERTAINSPIQGSAADILKIAMINLDKAL    +++K+LLQVHD
Sbjct  775  RELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHD  834

Query  832  EIILDVPLEELEDIKALVKQTMEEAIELAVPLKVDENTGKTWYEAK  877
            EI+L+VP +EL  IK LVK+TME A++LAVPL VDE+TG++WYEAK
Sbjct  835  EIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

121) polA in NC_009004


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score = 1016 bits (3850),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 598/886 (68%), Positives = 747/886 (85%), Gaps = 15/886 (1%)

Query  1    MEDKNRLLLIDGSSVAFRAFFALYNQLDRFKAPNGLHTNAIFAFHTMLSSLMERIQPTHV  60
            ME+KN+LLLIDGSSVAFRAFFALYNQ+DRFK  +GLHTNAI++FH ML  +M R++PTHV
Sbjct  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60

Query  61   LIAFDAGKTTFRTEMFADYKGGRSKTPDEFREQLPFIKEMIEKLGIRHYELANYEADDII  120
            L+AFDAGKTTFRTEM+ADYK+GR+KTPDEFREQ+++I+EM+  LGI  YEL +YEADDII
Sbjct  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120

Query  121  GTLDKMAEAPDVNFDVTIVTGDKDMIQLVDGNTRVEISKKGVAEFEEFTPDYLLEKMGLT  180
            GTLDKMAE  +V FDVTIV+GDKD+IQL D NT VEISKKGVAEFEEFTP YL+EKMGLT
Sbjct  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180

Query  181  PSQFIDLKALMGDSSDNYPGVTKVGEKTGLKLLQEFGSLENLYENVETLKASKMKDNLIA  240
            P+QFIDLKALMGD SDN PGVTK+GEKTGLKLL+EFGSLE +YE+++ +K+SKMK+NLI 
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  241  DKEMAFLSQQLATINTKAPLEIGLEDTLLKEKNVAELGQFYDEMGFSQFKSKLLADGGGE  300
            D++ AFLS+ LATINT +P+ IGL+D + +  +VA L+QFYDEM+F Q+K  L    +++
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGL----ASQ  296

Query  301  VTDETVSEEIKFEIVTDKSSVASVNADDFFYLETLGENYHREQIVAFAWGNSEKIYVSKN  360
            + +E V+  I ++ VT+  S    +A+D+FY+ETL +NYHRE I++FAWG++E+IY S +
Sbjct  297  MPQEPVA-VISYQEVTN-VSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTD  354

Query  361  LDLLTEMKF------PENTYDFKKNRVLLSHLNIELPLVKFDAMLAKYLISTTEDNKIST  414
            L LL+   F      P  TYDFK+++VLLSHL IEL    +DA LA+YL+ST EDN +ST
Sbjct  355  LSLLATDSFKQVFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELST  414

Query  415  IARLFDVGHLATDEEIFGKGTKLALPDDEILFDHLARKIRVLARAKEKMMAELIENEQEH  474
            IAR+F    L  D+ ++GKG+K A+PD ++L++HLARK++VL  +K +M+  L  +EQ +
Sbjct  415  IARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLD  474

Query  475  LLSDMELPLAEVLAKMEITGISVSQNTLEEIGAENEEKLASLTREIYDLAGEEFNINSPK  534
            L  ++ELPLA+VLAKMEI GI V++ TL++++ +N   + +LT+EIYD+AG+EFNINSPK
Sbjct  475  LYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPK  534

Query  535  QLGVILFEKLQLP--VGKKTKTGYSTAVDVLEDLAALSPVVAKILEYRQINKVQSTYVKG  592
            QLG ILFEK+QLP  + KKTKTGYSTAVDVLE LA+++P+VAKIL+YRQI K+QSTYV G
Sbjct  535  QLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIG  594

Query  593  LIPQIADDGKIHTRYVQDLTQTGRLSSVDPNLQNIPVRLEEGRKIRKAFVPsqdslllss  652
            L   I  DGKIHTRYVQDLTQTGRLSSVDPNLQNIP+RLE+GR IRKAF PS++  +L S
Sbjct  595  LQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLS  654

Query  653  dy-sqIELRVLAHISADEHLIDAFKHGADIHTSTAMRVFGIEKAEDVTANDRRNAKAVNF  711
               SQIELRVLAHIS+DEHLI AF++GADIHTSTAMRVFGI+KA DVTANDRRNAKAVNF
Sbjct  655  SDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNF  714

Query  712  GVVYGISDFGLARNLGITRKDAKNYIETYFERYPGIKTYMENIVREARDKGFVETMSHRR  771
            G+VYGISDFGL+ NLGITRK++K+YI+TYFERYPGIK+YMEN+VREA+DKG+VET+  RR
Sbjct  715  GIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRR  774

Query  772  RKIPDINARNFNVRGFAERTAINSPIQGSAADILKIAMINLDKALTERQSKSKLLLQVHD  831
            R +PDIN+RNFNVR+FAERTAINSPIQGSAADILKIAMINLDKAL     ++K+LLQVHD
Sbjct  775  RELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHD  834

Query  832  EIILDVPLEELEDIKALVKQTMEEAIELAVPLKVDDNTGKTWYEAK  877
            EI+L+VP +EL  IK LVK+TME A++LAVPL VD++TG++WYEAK
Sbjct  835  EIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

122) LLNZ_12535 in NC_017949


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score = 1016 bits (3850),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 598/886 (68%), Positives = 747/886 (85%), Gaps = 15/886 (1%)

Query  1    MEDKNRLLLIDGSSVAFRAFFALYNQLDRFKAPNGLHTNAIFAFHTMLSSLMERIQPTHV  60
            ME+KN+LLLIDGSSVAFRAFFALYNQ+DRFK  +GLHTNAI++FH ML  +M R++PTHV
Sbjct  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60

Query  61   LIAFDAGKTTFRTEMFADYKGGRSKTPDEFREQLPFIKEMIEKLGIRHYELANYEADDII  120
            L+AFDAGKTTFRTEM+ADYK+GR+KTPDEFREQ+++I+EM+  LGI  YEL +YEADDII
Sbjct  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120

Query  121  GTLDKMAEAPDVNFDVTIVTGDKDMIQLVDGNTRVEISKKGVAEFEEFTPDYLLEKMGLT  180
            GTLDKMAE  +V FDVTIV+GDKD+IQL D NT VEISKKGVAEFEEFTP YL+EKMGLT
Sbjct  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180

Query  181  PSQFIDLKALMGDSSDNYPGVTKVGEKTGLKLLQEFGSLENLYENVETLKASKMKDNLIA  240
            P+QFIDLKALMGD SDN PGVTK+GEKTGLKLL+EFGSLE +YE+++ +K+SKMK+NLI 
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  241  DKEMAFLSQQLATINTKAPLEIGLEDTLLKEKNVAELGQFYDEMGFSQFKSKLLADGGGE  300
            D++ AFLS+ LATINT +P+ IGL+D + +  +VA L+QFYDEM+F Q+K  L    +++
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGL----ASQ  296

Query  301  VTDETVSEEIKFEIVTDKSSVASVNADDFFYLETLGENYHREQIVAFAWGNSEKIYVSKN  360
            + +E V+  I ++ VT+  S    +A+D+FY+ETL +NYHRE I++FAWG++E+IY S +
Sbjct  297  MPQEPVA-VISYQEVTN-VSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTD  354

Query  361  LDLLTEMKF------PENTYDFKKNRVLLSHLNIELPLVKFDAMLAKYLISTTEDNKIST  414
            L LL+   F      P  TYDFK+++VLLSHL IEL    +DA LA+YL+ST EDN +ST
Sbjct  355  LSLLATDSFKQVFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELST  414

Query  415  IARLFDVGHLATDEEIFGKGTKLALPDDEILFDHLARKIRVLARAKEKMMAELIENEQEH  474
            IAR+F    L  D+ ++GKG+K A+PD ++L++HLARK++VL  +K +M+  L  +EQ +
Sbjct  415  IARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLD  474

Query  475  LLSDMELPLAEVLAKMEITGISVSQNTLEEIGAENEEKLASLTREIYDLAGEEFNINSPK  534
            L  ++ELPLA+VLAKMEI GI V++ TL++++ +N   + +LT+EIYD+AG+EFNINSPK
Sbjct  475  LYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPK  534

Query  535  QLGVILFEKLQLP--VGKKTKTGYSTAVDVLEDLAALSPVVAKILEYRQINKVQSTYVKG  592
            QLG ILFEK+QLP  + KKTKTGYSTAVDVLE LA+++P+VAKIL+YRQI K+QSTYV G
Sbjct  535  QLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIG  594

Query  593  LIPQIADDGKIHTRYVQDLTQTGRLSSVDPNLQNIPVRLEEGRKIRKAFVPsqdslllss  652
            L   I  DGKIHTRYVQDLTQTGRLSSVDPNLQNIP+RLE+GR IRKAF PS++  +L S
Sbjct  595  LQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLS  654

Query  653  dy-sqIELRVLAHISADEHLIDAFKHGADIHTSTAMRVFGIEKAEDVTANDRRNAKAVNF  711
               SQIELRVLAHIS+DEHLI AF++GADIHTSTAMRVFGI+KA DVTANDRRNAKAVNF
Sbjct  655  SDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNF  714

Query  712  GVVYGISDFGLARNLGITRKDAKNYIETYFERYPGIKTYMENIVREARDKGFVETMSHRR  771
            G+VYGISDFGL+ NLGITRK++K+YI+TYFERYPGIK+YMEN+VREA+DKG+VET+  RR
Sbjct  715  GIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRR  774

Query  772  RKIPDINARNFNVRGFAERTAINSPIQGSAADILKIAMINLDKALTERQSKSKLLLQVHD  831
            R +PDIN+RNFNVR+FAERTAINSPIQGSAADILKIAMINLDKAL     ++K+LLQVHD
Sbjct  775  RELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHD  834

Query  832  EIILDVPLEELEDIKALVKQTMEEAIELAVPLKVDDNTGKTWYEAK  877
            EI+L+VP +EL  IK LVK+TME A++LAVPL VD++TG++WYEAK
Sbjct  835  EIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

123) LACR_2445 in NC_008527


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score = 1013 bits (3839),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 596/886 (68%), Positives = 746/886 (85%), Gaps = 15/886 (1%)

Query  1    MEDKNRLLLIDGSSVAFRAFFALYNQLDRFKAPNGLHTNAIFAFHTMLSSLMERIQPTHV  60
            ME+KN+LLLIDGSSVAFRAFFALYNQ+DRFK  +GLHTNAI++FH ML  +M R++PTHV
Sbjct  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60

Query  61   LIAFDAGKTTFRTEMFADYKGGRSKTPDEFREQLPFIKEMIEKLGIRHYELANYEADDII  120
            L+AFDAGKTTFRTEM+ADYK+GR+KTPDEFREQ+++I+EM+  LGI  YEL +YEADDII
Sbjct  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120

Query  121  GTLDKMAEAPDVNFDVTIVTGDKDMIQLVDGNTRVEISKKGVAEFEEFTPDYLLEKMGLT  180
            GTLDKMAE  +V FDVTIV+GDKD+IQL D NT VEISKKGVAEFEEFTP YL+EKMGLT
Sbjct  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180

Query  181  PSQFIDLKALMGDSSDNYPGVTKVGEKTGLKLLQEFGSLENLYENVETLKASKMKDNLIA  240
            P+QFIDLKALMGD SDN PGVTK+GEKTGLKLL+EFGSLE +YE+++ +K+SKMK+NLI 
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  241  DKEMAFLSQQLATINTKTPLEIGLEDTLLKEKNVAELGQFYDEMGFSQFKSKLLTDGGGE  300
            D++ AFLS+ LATINT +P+ IGL+D + +  +VA L+QFYDEM+F Q+K  L    +++
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGL----ASQ  296

Query  301  VTDETVSEEIKFEIVTDKSSVASVNADDFFYLETLGENYHREQIVAFAWGNAEKIYVSKN  360
            + +E V+  I ++ VT+  S    +A+D+FY+ETL +NYHRE I++FAWG++E+IY S +
Sbjct  297  MPQEPVA-VISYQEVTN-VSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTD  354

Query  361  LDLLTEMKF------PENTYDFKKNRVLLSHLNIELPLVKFDAMLAKYLISTTEDNKIST  414
            L LL+   F      P  TYDFK+++VLLSHL IEL    +DA LA+YL+ST EDN +ST
Sbjct  355  LSLLATDSFKQVFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELST  414

Query  415  IARLFDVGHLATDEEIFGKGTKLALPDDEILFDHLARKIRVLARAKEKMMAELIENEQEH  474
            IAR+F    L  D+ ++GKG+K A+PD ++L++HLARK++VL  +K +M+  L  +EQ +
Sbjct  415  IARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLD  474

Query  475  LLSDMELPLAEVLAKMEITGISVSQNTLEEIGAENEEKLALLTREIYELAGEEFNINSPK  534
            L  ++ELPLA+VLAKMEI GI V++ TL++++ +N   +  LT+EIY++AG+EFNINSPK
Sbjct  475  LYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPK  534

Query  535  QLGVILFEKLQLP--VGKKTKTGYSTAVDVLEDLAALSPVVAKILEYRQINKVQSTYVKG  592
            QLG ILFEK+QLP  + KKTKTGYSTAVDVLE LA+++P+VAKIL+YRQI K+QSTYV G
Sbjct  535  QLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIG  594

Query  593  LIPQIADDGKIHTRYVQDLTQTGRLSSVDPNLQNIPVRLEEGRKIRKAFVPsqdslllss  652
            L   I  DGKIHTRYVQDLTQTGRLSSVDPNLQNIP+RLE+GR IRKAF PS++  +L S
Sbjct  595  LQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLS  654

Query  653  dy-sqIELRVLAHISADEHLIDAFKHGADIHTSTSMRVFGIEKAEDVTANDRRNAKAVNF  711
               SQIELRVLAHIS+DEHLI AF++GADIHTST+MRVFGI+KA DVTANDRRNAKAVNF
Sbjct  655  SDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNF  714

Query  712  GVVYGISDFGLARNLGITRKDAKNYIETYFERYPGIKTYMENIVREARDKGFVETMSHRR  771
            G+VYGISDFGL+ NLGITRK++K+YI+TYFERYPGIK+YMEN+VREA+DKG+VET+  RR
Sbjct  715  GIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRR  774

Query  772  RKIPDINARNFNVRGFAERTAINSPIQGSAADILKIAMINLDKALTERQSKSKLLLQVHD  831
            R +PDIN+RNFNVR+FAERTAINSPIQGSAADILKIAMINLDKAL     ++K+LLQVHD
Sbjct  775  RELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHD  834

Query  832  EIILDVPLEELEEIQVLVKETMEEAIELAVPLKVDENTGKTWYEAK  877
            EI+L+VP +EL  I+ LVK+TME A++LAVPL VDE+TG++WYEAK
Sbjct  835  EIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

124) polA in NC_019435


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score = 1013 bits (3838),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 595/886 (68%), Positives = 746/886 (85%), Gaps = 15/886 (1%)

Query  1    MEDKNRLLLIDGSSVAFRAFFALYNQLDRFKAPNGLHTNAIFAFHTMLSSLMERIQPTHV  60
            ME+KN+LLLIDGSSVAFRAFFALYNQ+DRFK  +GLHTNAI++FH ML  +M R++PTHV
Sbjct  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60

Query  61   LIAFDAGKTTFRTEMFADYKGGRSKTPDEFREQLPFIKEMIEKLGIRHYELANYEADDII  120
            L+AFDAGKTTFRTEM+ADYK+GR+KTPDEFREQ+++I+EM+  LGI  YEL +YEADDII
Sbjct  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120

Query  121  GTLDKMAEAPDVNFDVTIVTGDKDMIQLVDGNTRVEISKKGVAEFEEFTPDYLLEKMGLT  180
            GTLDKMAE  +V FDVTIV+GDKD+IQL D NT VEISKKGVAEFEEFTP YL+EKMGLT
Sbjct  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180

Query  181  PSQFIDLKALMGDSSDNYPGVTKVGEKTGLKLLQEFGSLENLYENVETLKASKMKDNLIA  240
            P+QFIDLKALMGD SDN PGVTK+GEKTGLKLL+EFGSLE +YE+++ +K+SKMK+NLI 
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  241  DKEMAFLSQQLATINTKTPLEIGLEDTLLKEKNVAELGQFYDEMGFSQFKSKLLTDGGGE  300
            D++ AFLS+ LATINT +P+ IGL+D + +  +VA L+QFYDEM+F Q+K  L    +++
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGL----ASQ  296

Query  301  VTDETVSEEIKFEIVTDKSSVASVNADDFFYLETLGENYHREQIVAFAWGNAEKIYVSKN  360
            + +E V+  I ++ VT+  S    +A+D+FY+ETL +NYHRE I++FAWG++E+IY S +
Sbjct  297  MPQEPVA-VISYQEVTN-VSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTD  354

Query  361  LDLLTEMKF------PENTYDFKKNRVLLSHLNIELPLVKFDAMLAKYLISTTEDNKIST  414
            L LL+   F      P  TYDFK+++VLLSHL IEL    +DA LA+YL+ST EDN +ST
Sbjct  355  LSLLATDSFKQVFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELST  414

Query  415  IARLFDVGHLATDEEIFGKGTKLALPDDEILFDHLARKIRVLARAKEKMMAELIENEQEH  474
            IAR+F    L  D+ ++GKG+K A+PD ++L++HLARK++VL  +K +M+  L  +EQ +
Sbjct  415  IARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLD  474

Query  475  LLSDMELPLAEVLAKMEITGISVSQNTLEEIGAENEEKLALLTREIYELAGEEFNINSPK  534
            L  ++ELPLA+VLAKMEI GI V++ TL++++ +N   +  LT+EIY++AG+EFNINSPK
Sbjct  475  LYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPK  534

Query  535  QLGVILFEKLQLP--VGKKTKTGYSTAVDVLEDLAALSPVVAKILEYRQINKVQSTYVKG  592
            QLG ILFEK+QLP  + KKTKTGYSTAVDVLE LA+++P+VAKIL+YRQI K+QSTYV G
Sbjct  535  QLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIG  594

Query  593  LIPQIADDGKIHTRYVQDLTQTGRLSSVDPNLQNIPVRLEEGRKIRKAFVPsqdslllss  652
            L   I  DGKIHTRYVQDLTQTGRLSSVDPNLQNIP+RLE+GR IRKAF PS++  +L S
Sbjct  595  LQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLS  654

Query  653  dy-sqIELRVLAHISADEHLIDAFKHGADIHTSTSMRVFGIEKAEDVTANDRRNAKAVNF  711
               SQIELRVLAHIS+DEHLI AF++GADIHTST+MRVFGI+KA DVTANDRRNAKAVNF
Sbjct  655  SDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNF  714

Query  712  GVVYGISDFGLARNLGITRKDAKNYIETYFERYPGIKTYMENIVREARDKGFVETMSHRR  771
            G+VYGISDFGL+ NLGITRK++K+YI+TYFERYPGIK+YMEN+VREA+DKG+VET+  RR
Sbjct  715  GIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRR  774

Query  772  RKIPDINARNFNVRGFAERTAINSPIQGSAADILKIAMINLDRALTERQSKSKLLLQVHD  831
            R +PDIN+RNFNVR+FAERTAINSPIQGSAADILKIAMINLD+AL     ++K+LLQVHD
Sbjct  775  RELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHD  834

Query  832  EIILDVPLEELEEIQALVKETMEEAIELAVPLKVDENTGKTWYEAK  877
            EI+L+VP +EL  I+ LVK+TME A++LAVPL VDE+TG++WYEAK
Sbjct  835  EIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

125) LCGL_1869 in NC_017490


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  969 bits (3670),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 564/880 (65%), Positives = 717/880 (82%), Gaps = 12/880 (1%)

Query  3    NKKNKLLLIDGSSLAFRAFFALYNQVDRFVAPSGLHTNAIYGFHLMLNNLVERLEPNHVL  62
            ++KNKLLLIDGSS+AFRAFFALYNQ+DRF   SGLHTNAIYGFHLML++++ R+ P HVL
Sbjct  2    ENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVL  61

Query  63   IAFDAGKTTFRTEMFAAYKDGRARTPDEFREQLPFIKELIEKLGYNHYELKNYEADDIIG  122
            +AFDAGKTTFRTEM+A YK GRA+TPDEFREQ+++I+E++  LG   YEL +YEADDIIG
Sbjct  62   VAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIG  121

Query  123  TLDKMAELPEAGDYDVTIVTGDKDLIQLVDSNTTVEISKKGVAEFESFTPAYLMEKTGLT  182
            TLDKMAE  E   +DVTIV+GDKDLIQL D NT VEISKKGVAEFE FTPAYLMEK GLT
Sbjct  122  TLDKMAERTEVP-FDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180

Query  183  PQQFIDLKGLMGDSSDNYPGVTKVGEKTALKLLQEWGSIDNLYENINSLKKSKMKENLIA  242
            P+QFIDLK+LMGD SDN PGVTK+GEKT+LKLL+E GS++ +YE+I+++K SKMKENLI 
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  243  DREMAFLSRTLATIDTKSPIEIDLADTLIKPVDAAELIKFYDEMGFAQFKAKLETAEADE  302
            DR+ AFLS+TLATI+T SPI I+L D + +  D A L +FYDEM+F Q+K  L +  ++E
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQE  300

Query  303  --VTLSFEVVEEAADILVDKDDFFYIEILNENYHKEEIIGFAWGNEEKVFVSKNTELL--  358
                +S++ V + +  L   +D+FY+E L +NYH+E IIGFAWG+ E+++ S +  LL  
Sbjct  301  PVAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLAT  360

Query  359  KHF--VF--PENTYDFKKNKVLLHRLGIELPTAKYDSMLAKYLISTTEDNKVETIGRLFA  414
              F  VF  P  TYDFK++KVLL +LGIEL ++ YD+ LA+YL+ST EDN + TI+R+F+
Sbjct  361  DSFKQVFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIFT  420

Query  415  NKYISTDEEVYGKGAKRRIPEDEILFKHLAGKIHVLATTKAVMIQNLEENEQYHLLTEME  474
            +  +  D+ VYGKGAKR +P+ ++L+ HLA K+ VL  +K+ M+++L  +EQ +L  ++E
Sbjct  421  DISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNIE  480

Query  475  LPLANVLAKMEIAGIAAEVSTLEEIGAANQNLIADLTEQIYALAGEEFNINSPKQLGVIL  534
            LPLANVLAKMEI GI  + +TL++++  N+ +I  LT++IY +AG+EFNINSPKQLG IL
Sbjct  481  LPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSIL  540

Query  535  FEKLQLP--HGKKTKTGYSTAADILENLAQDYELVAKILEYRQISKIQSTYVQGLIPQIA  592
            FEK+QLP    KKTKTGYSTA D+LE LA    +VAKIL+YRQI+K+QSTYV GL   I 
Sbjct  541  FEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYIL  600

Query  593  EDGRIHTRYVQDLTQTGRLSSIDPNLQNIPVRLEAGRLIRKAFVAA-ENNILLSSDYSQI  651
             DG+IHTRYVQDLTQTGRLSS+DPNLQNIP+RLE GRLIRKAF ++ E+ +LLSSDYSQI
Sbjct  601  ADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQI  660

Query  652  ELRVLAHMSKDEHLIDAFNHGADIHSSTAMRVFNIDKPENVTPNDRRNAKAVNFGISYGE  711
            ELRVLAH+S DEHLI AFN+GADIH+STAMRVF IDK+ +VT+NDRRNAKAVNFGI YG 
Sbjct  661  ELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGI  720

Query  712  TEYGLAKRLSISNKEAAEMIQAYFERYPGVANYIAETKREAKDKGYVSTMFNRRRKLPEI  771
            +++GL++ L+I+ K++   I++YFERYPG+  Y+ +  REAKDKGYV T+F+RRR LP+I
Sbjct  721  SDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDI  780

Query  772  NNRNFMVRQGAERQAINAPIQGSAGDILKIAMINLDAALSEGKFKAKLLLQVHDEIILEV  831
            N+RNF VR  AER AIN+PIQGSA+DILKIAMINLD AL  G F+AK+LLQVHDEI+LEV
Sbjct  781  NSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEV  840

Query  832  PKEELTAVQTLVKQTMESAVELNVPLIADENTGDSWYEAK  871
            P++ELTA++ LVK+TME+AV+L VPL  DE+TG+SWYEAK
Sbjct  841  PNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

126) LCGT_1848 in NC_015930


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  967 bits (3666),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 563/880 (64%), Positives = 717/880 (82%), Gaps = 12/880 (1%)

Query  3    NKKNKLLLIDGSSLAFRAFFALYNQVDRFVAPSGLHTNAIYGFHLMLNNLVERLEPNHVL  62
            ++KNKLLLIDGSS+AFRAFFALYNQ+DRF   SGLHTNAIYGFHLML++++ R+ P HVL
Sbjct  2    ENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVL  61

Query  63   IAFDAGKTTFRTEMFAAYKDGRARTPDEFREQLPFIKELIEKLGYNHYELKNYEADDIIG  122
            +AFDAGKTTFRTEM+A YK GRA+TPDEFREQ+++I+E++  LG   YEL +YEADDIIG
Sbjct  62   VAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIG  121

Query  123  TLDKMAELPEAGDYDVTIVTGDKDLIQLVDSNTTVEISKKGVAEFESFTPAYLMEKTGLT  182
            TLDKMAE  E   +DVTIV+GDKDLIQL D NT VEISKKGVAEFE FTPAYLMEK GLT
Sbjct  122  TLDKMAERTEVP-FDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180

Query  183  PQQFIDLKGLMGDSSDNYPGVTKVGEKTALKLLQEWGSIDNLYENINSLKKSKMKENLIA  242
            P+QFIDLK+LMGD SDN PGVTK+GEKT+LKLL+E GS++ +YE+I+++K SKMKENLI 
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  243  DREMAFLSRTLTTIDTKSPIEIDLADTLIKPVDAAELIKFYDEMGFAQFKAKLETAEADE  302
            DR+ AFLS+TL+TI+T SPI I+L D + +  D A L +FYDEM+F Q+K  L +  ++E
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQE  300

Query  303  --VTLSFEVVEEAADILVDKDDFFYIEILNENYHKEEIIGFAWGNEEKVFVSKNTELL--  358
                +S++ V + +  L   +D+FY+E L +NYH+E IIGFAWG+ E+++ S +  LL  
Sbjct  301  PVAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLAT  360

Query  359  KHF--VF--PENTYDFKKNKVLLHRLGIELPTAKYDSMLAKYLISTTEDNKVETIGRLFA  414
              F  VF  P  TYDFK++KVLL +LGIEL ++ YD+ LA+YL+ST EDN + TI+R+F+
Sbjct  361  DSFKQVFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARIFT  420

Query  415  NKYISTDEEVYGKGAKRRIPEDEILFKHLAGKIHVLATTKAVMIQNLEENEQYHLLTEME  474
            +  +  D+ VYGKGAKR +P+ ++L+ HLA K+ VL  +K+ M+++L  +EQ +L  ++E
Sbjct  421  DISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNIE  480

Query  475  LPLANVLAKMEIAGIAAEVSTLEEIGAANQNLIADLTEQIYALAGEEFNINSPKQLGVIL  534
            LPLANVLAKMEI GI  + +TL++++  N+ +I  LT++IY +AG+EFNINSPKQLG IL
Sbjct  481  LPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSIL  540

Query  535  FEKLQLP--HGKKTKTGYSTAADILENLAQDYELVAKILEYRQISKIQSTYVQGLIPQIA  592
            FEK+QLP    KKTKTGYSTA D+LE LA    +VAKIL+YRQI+K+QSTYV GL   I 
Sbjct  541  FEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYIL  600

Query  593  EDGRIHTRYVQDLTQTGRLSSIDPNLQNIPVRLEAGRLIRKAFVAA-ENNILLSSDYSQI  651
             DG+IHTRYVQDLTQTGRLSS+DPNLQNIP+RLE GRLIRKAF ++ E+ +LLSSDYSQI
Sbjct  601  ADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQI  660

Query  652  ELRVLAHMSKDEHLIDAFNHGADIHSSTAMRVFNIDKPENVTPNDRRNAKAVNFGISYGE  711
            ELRVLAH+S DEHLI AFN+GADIH+STAMRVF IDK+ +VT+NDRRNAKAVNFGI YG 
Sbjct  661  ELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGI  720

Query  712  TEYGLAKRLSISNKEAAEMIQAYFERYPGVANYIAETKREAKDKGYVSTMFNRRRKLPEI  771
            +++GL++ L+I+ K++   I++YFERYPG+  Y+ +  REAKDKGYV T+F+RRR LP+I
Sbjct  721  SDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDI  780

Query  772  NNRNFMVRQGAERQAINAPIQGSAGDILKIAMINLDAALSEGKFKAKLLLQVHDEIILEV  831
            N+RNF VR  AER AIN+PIQGSA+DILKIAMINLD AL  G F+AK+LLQVHDEI+LEV
Sbjct  781  NSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEV  840

Query  832  PKEELTAVQTLVKQTMESAVELNVPLIADENTGDSWYEAK  871
            P++ELTA++ LVK+TME+AV+L VPL  DE+TG+SWYEAK
Sbjct  841  PNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

127) llh_12435 in NC_017492


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  942 bits (3568),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 557/835 (67%), Positives = 700/835 (84%), Gaps = 15/835 (1%)

Query  1    MERIQPTHVLIAFDAGKTTFRTEMFADYKGGRSKTPDEFREQLPFIKEMIEKLGIRHYEL  60
            M R++PTHVL+AFDAGKTTFRTEM+ADYK+GR+KTPDEFREQ+++I+EM+  LGI  YEL
Sbjct  52   MKRVRPTHVLVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYEL  111

Query  61   ANYEADDIIGTLDKMAEAPDVNFDVTIVTGDKDMIQLVDGNTRVEISKKGVAEFEEFTPD  120
             +YEADDIIGTLDKMAE  +V FDVTIV+GDKD+IQL D NT VEISKKGVAEFEEFTP 
Sbjct  112  EHYEADDIIGTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPA  171

Query  121  YLLEKMGLTPSQFIDLKALMGDSSDNYPGVTKVGEKTGLKLLQEFGSLENLYENVETLKA  180
            YL+EKMGLTP+QFIDLKALMGD SDN PGVTK+GEKTGLKLL+EFGSLE +YE+++ +K+
Sbjct  172  YLMEKMGLTPNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKT  231

Query  181  SKMKDNLIADKEMAFLSQQLATINTKTPLEIGLEDTLLKEKNVAELGQFYDEMGFSQFKS  240
            SKMK+NLI D++ AFLS+ LATINT +P+ IGL+D + +  +VA L+QFYDEM+F Q+K 
Sbjct  232  SKMKENLINDRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKK  291

Query  241  KLLTDGGGEVTDETVSEEIKFEIVTDKSSVASVNADDFFYLETLGENYHREQIVAFAWGN  300
             L    ++++ +E V+  I ++ VT+  S    +A+D+FY+ETL +NYHRE I++FAWG+
Sbjct  292  GL----ASQMPQEPVA-VISYQEVTN-VSADLFSAEDIFYFETLRDNYHREAIIGFAWGH  345

Query  301  AEKIYVSKNLDLLTEMKF------PENTYDFKKNRVLLSHLNIELPLVKFDAMLAKYLIS  354
            +E+IY S +L LL+   F      P  TYDFK+++VLLSHL IEL    +DA LA+YL+S
Sbjct  346  GEQIYASTDLSLLATDSFKQVFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLS  405

Query  355  TTEDNKISTIARLFDVGHLATDEEIFGKGTKLALPDDEILFDHLARKIRVLARAKEKMMA  414
            T EDN +STIAR+F    L  D+ ++GKG+K A+PD ++L++HLARK++VL  +K +M+ 
Sbjct  406  TVEDNELSTIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLD  465

Query  415  ELIENEQEHLLSDMELPLAEVLAKMEITGISVSQNTLEEIGAENEEKLALLTREIYELAG  474
             L  +EQ +L  ++ELPLA+VLAKMEI GI V++ TL++++ +N   +  LT+EIY++AG
Sbjct  466  KLTAHEQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAG  525

Query  475  EEFNINSPKQLGVILFEKLQLP--VGKKTKTGYSTAVDVLEDLAALSPVVAKILEYRQIN  532
            +EFNINSPKQLG ILFEK+QLP  + KKTKTGYSTAVDVLE LA+++P+VAKIL+YRQI 
Sbjct  526  QEFNINSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQIT  585

Query  533  KVQSTYVKGLIPQIADDGKIHTRYVQDLTQTGRLSSVDPNLQNIPVRLEEGRKIRKAFVP  592
            K+QSTYV GL   I  DGKIHTRYVQDLTQTGRLSSVDPNLQNIP+RLE+GR IRKAF P
Sbjct  586  KLQSTYVIGLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTP  645

Query  593  sqdslllssdy-sqIELRVLAHISADEHLIDAFKHGADIHTSTSMRVFGIEKAEDVTAND  651
            S++  +L S   SQIELRVLAHIS+DEHLI AF++GADIHTST+MRVFGI+KA DVTAND
Sbjct  646  SHEDAVLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTAND  705

Query  652  RRNAKAVNFGVVYGISDFGLARNLGITRKDAKNYIETYFERYPGIKTYMENIVREARDKG  711
            RRNAKAVNFG+VYGISDFGL+ NLGITRK++K+YI+TYFERYPGIK+YMEN+VREA+DKG
Sbjct  706  RRNAKAVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKG  765

Query  712  FVETMSHRRRKIPDINARNFNVRGFAERTAINSPIQGSAADILKIAMINLDKALTERQSK  771
            +VET+  RRR +PDIN+RNFNVR+FAERTAINSPIQGSAADILKIAMINLDKAL     +
Sbjct  766  YVETLFKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFR  825

Query  772  SKLLLQVHDEIILDVPLEELEEIQALVKETMEEAIELAVPLKVDENTGKTWYEAK  826
            +K+LLQVHDEI+L+VP +EL  I+ LVK+TME A++LAVPL VDE+TG++WYEAK
Sbjct  826  AKMLLQVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

128) EFAU004_01550 in NC_017022


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  877 bits (3322),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 521/884 (59%), Positives = 685/884 (78%), Gaps = 10/884 (1%)

Query  2    TKNKLLLVDGNSVAFRAFFALHNSLERFKNRNGLHTNAIYAFNTMFENVMQKEQPTHVLV  61
             KNKLLL+DG+SVAFRAFFAL N ++RFKN++GLHTNAIY+F+ M++++M++ +PTHVLV
Sbjct  3    NKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLV  62

Query  62   AFDAGKTTFRTEMYAEYKGGRSKTPGEFKEQMPYIRDLLTGLGVQYYELPNYEADDIIGT  121
            AFDAGKTTFRTEMYA+YK+GR+KTP+EF+EQ +YIR++LT+LG+ YYEL +YEADDIIGT
Sbjct  63   AFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGT  122

Query  122  LAEKVDKDQ--FDVVVLSGDRDLTQLASKEVKVDITVKGVSDIESYTPEHVAEKYDGLTP  179
            L    ++ +  FDV ++SGD+DL QL+  +  V+I+ KGV+++E +TP  + EK  GLTP
Sbjct  123  LDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEK-MGLTP  181

Query  180  KQIIDMKGLAGDASDNIPGVTKIGEKTAIKLLKQYGSVEGIYEHIDEMKQSKMKENLIND  239
            +Q+ID+K+L GD SDNIPGVTKIGEKT++KLL ++GS+EGIYEHID  K SKMKENLIND
Sbjct  182  NQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIND  241

Query  240  KEQAFLSKKLATINTSAPVDVSIDSLKYEGKNLDKLVPFYKEMDFNQFLSKLNIVEEEVK  299
            ++QAFLSK LATINT++P+ +++D + Y+G ++  L  FY EMDF Q+   L     +  
Sbjct  242  RDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEP  301

Query  300  MDDILFEVVHEFKEEMFTTDMALYVEMMGDNYHTEEIVGVAWGTEKKIYVTNDLSVFENR  359
            +  I ++ V +   ++F+++  +Y E + DNYH E I+G AWG   +IY + DLS++   
Sbjct  302  VAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLATD  361

Query  360  AFHSWITDPTRLKKVYDAKRTYVALNRYTGKTKGIDFDVLLGAYLLDTNEKSTDIEGIAA  419
            +F   +  P      YD KR+ V L++      +  +D  L+ YLL T E   ++  IA 
Sbjct  362  SFKQVFQKPI---ATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVE-DNELSTIAR  417

Query  420  HYGYNDIQSDEAVYGKGAKKGLPEEEELFFAHLARKVAAINALTPKLSQELAEKNQEDLF  479
             +    ++ D++VYGKGAK+++P+ + L+  HLARKV  +    +++ + L+  +Q DL+
Sbjct  418  IFTDISLEEDDTVYGKGAKRAVPDKDVLL-EHLARKVKVLLDSKSQMLDKLTAHEQLDLY  476

Query  480  RKMELPLSIILAEMEISGIKVDATRLQEMKGEFSARLREIEQKIYEEAGEEFNLNSPKQL  539
            +++ELPL+ +LA MEI GIKV+ + LQ+M  +    +  + Q IY+ AG+EFN+NSPKQL
Sbjct  477  QNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQL  536

Query  540  GVILFEKMGLP--VIKKTKTGYSTAVDVLEQLREQAPIVEDILTYRQIAKIQSTYVEGLL  597
            G ILFEKM LP  + KKTKTGYSTAVDVLE+L   APIV  IL YRQI+K+QSTYV GL 
Sbjct  537  GSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQ  596

Query  598  KVIQSDGKVHTRYVQTLTQTGRLSSVDPNLQNIPIRLDEGRKIRQAFVPREKDWLIYSSD  657
              I +DGK+HTRYVQ LTQTGRLSSVDPNLQNIPIRL++GR IR+AF P + D ++ SSD
Sbjct  597  DYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSD  656

Query  658  YSQIELRVLAHISNDEHLKAAFLEGQDIHASTAMRVFGIEKAEDVTPNMRRQAKAVNFGI  717
            YSQIELRVLAHIS DEHL AAF EG DIH+STAMRVFGI+KA DVT+N RR+AKAVNFGI
Sbjct  657  YSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGI  716

Query  718  VYGISDYGLSQNLGISRKAAQQYIDTYFEKYPGVKEYMERIVREAKDQGYVETLYHRRRY  777
            VYGISD+GLS+NLGI+RK ++ YIDTYFE+YPG+K YME +VREAKD+GYVETL+ RRR 
Sbjct  717  VYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRE  776

Query  778  LPDINSRNYNIRSFAERTAINTPIQGSAADILKIAMIELDKRLKETGLQATMLLQVHDEL  837
            LPDINSRN+N+RSFAERTAIN+PIQGSAADILKIAMI+LDK L+  G++A MLLQVHDE+
Sbjct  777  LPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEI  836

Query  838  VFEVPEKELESLDKLVKEVMEQAVSLHVPLITDSSWGKTWYEAK  881
            V+EVP+ EL ++ KLVK+ ME AV L VPL  D S G++WYEAK
Sbjct  837  VLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

129) EFAU085_01632 in NC_021994


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  877 bits (3322),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 521/884 (59%), Positives = 685/884 (78%), Gaps = 10/884 (1%)

Query  2    TKNKLLLVDGNSVAFRAFFALHNSLERFKNRNGLHTNAIYAFNTMFENVMQKEQPTHVLV  61
             KNKLLL+DG+SVAFRAFFAL N ++RFKN++GLHTNAIY+F+ M++++M++ +PTHVLV
Sbjct  3    NKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLV  62

Query  62   AFDAGKTTFRTEMYAEYKGGRSKTPGEFKEQMPYIRDLLTGLGVQYYELPNYEADDIIGT  121
            AFDAGKTTFRTEMYA+YK+GR+KTP+EF+EQ +YIR++LT+LG+ YYEL +YEADDIIGT
Sbjct  63   AFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGT  122

Query  122  LAEKVDKDQ--FDVVVLSGDRDLTQLASKEVKVDITVKGVSDIESYTPEHVAEKYDGLTP  179
            L    ++ +  FDV ++SGD+DL QL+  +  V+I+ KGV+++E +TP  + EK  GLTP
Sbjct  123  LDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEK-MGLTP  181

Query  180  KQIIDMKGLAGDASDNIPGVTKIGEKTAIKLLKQYGSVEGIYEHIDEMKQSKMKENLIND  239
            +Q+ID+K+L GD SDNIPGVTKIGEKT++KLL ++GS+EGIYEHID  K SKMKENLIND
Sbjct  182  NQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIND  241

Query  240  KEQAFLSKKLATINTSAPVDVSIDSLKYEGKNLDKLVPFYKEMDFNQFLSKLNIVEEEVK  299
            ++QAFLSK LATINT++P+ +++D + Y+G ++  L  FY EMDF Q+   L     +  
Sbjct  242  RDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEP  301

Query  300  MDDILFEVVHEFKEEMFTTDMALYVEMMGDNYHTEEIVGVAWGTEKKIYVTNDLSVFENR  359
            +  I ++ V +   ++F+++  +Y E + DNYH E I+G AWG   +IY + DLS++   
Sbjct  302  VAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLATD  361

Query  360  AFHSWITDPTRLKKVYDAKRTYVALNRYTGKTKGIDFDVLLGAYLLDTNEKSTDIEGIAA  419
            +F   +  P      YD KR+ V L++      +  +D  L+ YLL T E   ++  IA 
Sbjct  362  SFKQVFQKPI---ATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVE-DNELSTIAR  417

Query  420  HYGYNDIQSDEAVYGKGAKKGLPEEEELFFAHLARKVAAINALTPKLSQELADKNQEDLF  479
             +    ++ D++VYGKGAK+++P+ + L+  HLARKV  +    +++ + L+  +Q DL+
Sbjct  418  IFTDISLEEDDTVYGKGAKRAVPDKDVLL-EHLARKVKVLLDSKSQMLDKLTAHEQLDLY  476

Query  480  RKMELPLSIILAEMEISGIKVDATRLQEMKGEFSARLREIEQKIYEEAGEEFNLNSPKQL  539
            +++ELPL+ +LA MEI GIKV+ + LQ+M  +    +  + Q IY+ AG+EFN+NSPKQL
Sbjct  477  QNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQL  536

Query  540  GVILFEKMGLP--VIKKTKTGYSTAVDVLEQLREQAPIVEDILTYRQIAKIQSTYVEGLL  597
            G ILFEKM LP  + KKTKTGYSTAVDVLE+L   APIV  IL YRQI+K+QSTYV GL 
Sbjct  537  GSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQ  596

Query  598  KVIQSDGKVHTRYVQTLTQTGRLSSVDPNLQNIPIRLDEGRKIRQAFVPREKDWLIYSSD  657
              I +DGK+HTRYVQ LTQTGRLSSVDPNLQNIPIRL++GR IR+AF P + D ++ SSD
Sbjct  597  DYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSD  656

Query  658  YSQIELRVLAHISNDEHLKAAFLEGQDIHASTAMRVFGIEKAEDVTPNMRRQAKAVNFGI  717
            YSQIELRVLAHIS DEHL AAF EG DIH+STAMRVFGI+KA DVT+N RR+AKAVNFGI
Sbjct  657  YSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGI  716

Query  718  VYGISDYGLSQNLGISRKAAQQYIDTYFEKYPGVKEYMERIVREAKDQGYVETLYHRRRY  777
            VYGISD+GLS+NLGI+RK ++ YIDTYFE+YPG+K YME +VREAKD+GYVETL+ RRR 
Sbjct  717  VYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRE  776

Query  778  LPDINSRNYNIRSFAERTAINTPIQGSAADILKIAMIELDKRLKETGLQATMLLQVHDEL  837
            LPDINSRN+N+RSFAERTAIN+PIQGSAADILKIAMI+LDK L+  G++A MLLQVHDE+
Sbjct  777  LPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEI  836

Query  838  VFEVPEKELESLDKLVKEVMEQAVSLHVPLITDSSWGKTWYEAK  881
            V+EVP+ EL ++ KLVK+ ME AV L VPL  D S G++WYEAK
Sbjct  837  VLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

130) polA in NC_017960


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  877 bits (3320),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 520/884 (59%), Positives = 685/884 (78%), Gaps = 10/884 (1%)

Query  2    TKNKLLLVDGNSVAFRAFFPLHNSLERFKNRNGLHTNAIYAFNTMFENVMQKEQPTHVLV  61
             KNKLLL+DG+SVAFRAFF+L N ++RFKN++GLHTNAIY+F+ M++++M++ +PTHVLV
Sbjct  3    NKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLV  62

Query  62   AFDAGKTTFRTEMYAEYKGGRSKTPGEFKEQMPYIRDLLTGLGVQYYELPNYEADDIIGT  121
            AFDAGKTTFRTEMYA+YK+GR+KTP+EF+EQ +YIR++LT+LG+ YYEL +YEADDIIGT
Sbjct  63   AFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGT  122

Query  122  LAEKVDKDQ--FDVVVLSGDRDLTQLASKEVKVDITVKGVSDIESYTPEHVAEKYDGLTP  179
            L    ++ +  FDV ++SGD+DL QL+  +  V+I+ KGV+++E +TP  + EK  GLTP
Sbjct  123  LDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEK-MGLTP  181

Query  180  KQIIDMKGLAGDASDNIPGVTKIGEKTAIKLLKQYGSVEGIYEHIDEMKQSKMKENLIND  239
            +Q+ID+K+L GD SDNIPGVTKIGEKT++KLL ++GS+EGIYEHID  K SKMKENLIND
Sbjct  182  NQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIND  241

Query  240  KEQAFLSKKLATINTSAPVDVSIDSLKYEGKNLDKLVPFYKEMDFNQFLSKLNIVEEEVK  299
            ++QAFLSK LATINT++P+ +++D + Y+G ++  L  FY EMDF Q+   L     +  
Sbjct  242  RDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEP  301

Query  300  MDDILFEVVHEFKEEMFTTDMALYVEMMGDNYHTEEIVGVAWGTEKKIYVTNDLSVFENR  359
            +  I ++ V +   ++F+++  +Y E + DNYH E I+G AWG   +IY + DLS++   
Sbjct  302  VAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLATD  361

Query  360  AFHSWITDPTRLKKVYDAKRTYVALNRYTGKTKGIDFDVLLGAYLLDTNEKSTDIEGIAA  419
            +F   +  P      YD KR+ V L++      +  +D  L+ YLL T E   ++  IA 
Sbjct  362  SFKQVFQKPI---ATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVE-DNELSTIAR  417

Query  420  HYGYNDIQSDEAVYGKGAKKGLPEEEELFFAHLARKVAAINALTPKLSQELAEKNQEDLF  479
             +    ++ D++VYGKGAK+++P+ + L+  HLARKV  +    +++ + L+  +Q DL+
Sbjct  418  IFTDISLEEDDTVYGKGAKRAVPDKDVLL-EHLARKVKVLLDSKSQMLDKLTAHEQLDLY  476

Query  480  RKMELPLSIILAEMEISGIKVDATRLQEMKGEFSARLREIEQKIYEEAGEEFNLNSPKQL  539
            +++ELPL+ +LA MEI GIKV+ + LQ+M  +    +  + Q IY+ AG+EFN+NSPKQL
Sbjct  477  QNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQL  536

Query  540  GVILFEKMGLP--VIKKTKTGYSTAVDVLEQLREQAPIVEDILTYRQIAKIQSTYVEGLL  597
            G ILFEKM LP  + KKTKTGYSTAVDVLE+L   APIV  IL YRQI+K+QSTYV GL 
Sbjct  537  GSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQ  596

Query  598  KVIQSDGKVHTRYVQTLTQTGRLSSVDPNLQNIPIRLDEGRKIRQAFVPREKDWLIYSSD  657
              I +DGK+HTRYVQ LTQTGRLSSVDPNLQNIPIRL++GR IR+AF P + D ++ SSD
Sbjct  597  DYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSD  656

Query  658  YSQIELRVLAHISNDEHLKAAFLEGQDIHASTAMRVFGIEKAEDVTPNMRRQAKAVNFGI  717
            YSQIELRVLAHIS DEHL AAF EG DIH+STAMRVFGI+KA DVT+N RR+AKAVNFGI
Sbjct  657  YSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGI  716

Query  718  VYGISDYGLSQNLGISRKAAQQYIDTYFEKYPGVKEYMERIVREAKDQGYVETLYHRRRY  777
            VYGISD+GLS+NLGI+RK ++ YIDTYFE+YPG+K YME +VREAKD+GYVETL+ RRR 
Sbjct  717  VYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRE  776

Query  778  LPDINSRNYNIRSFAERTAINTPIQGSAADILKIAMIELDKRLKETGLQATMLLQVHDEL  837
            LPDINSRN+N+RSFAERTAIN+PIQGSAADILKIAMI+LDK L+  G++A MLLQVHDE+
Sbjct  777  LPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEI  836

Query  838  VFEVPEKELESLDKLVKEVMEQAVSLHVPLITDSSWGKTWYEAK  881
            V+EVP+ EL ++ KLVK+ ME AV L VPL  D S G++WYEAK
Sbjct  837  VLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

131) M7W_1304 in NC_020207


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  877 bits (3322),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 521/884 (59%), Positives = 685/884 (78%), Gaps = 10/884 (1%)

Query  2    TKNKLLLVDGNSVAFRAFFALHNSLERFKNRNGLHTNAIYAFNTMFENVMQKEQPTHVLV  61
             KNKLLL+DG+SVAFRAFFAL N ++RFKN++GLHTNAIY+F+ M++++M++ +PTHVLV
Sbjct  3    NKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLV  62

Query  62   AFDAGKTTFRTEMYAEYKGGRSKTPGEFKEQMPYIRDLLTGLGVQYYELPNYEADDIIGT  121
            AFDAGKTTFRTEMYA+YK+GR+KTP+EF+EQ +YIR++LT+LG+ YYEL +YEADDIIGT
Sbjct  63   AFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGT  122

Query  122  LAEKVDKDQ--FDVVVLSGDRDLTQLASKEVKVDITVKGVSDIESYTPEHVAEKYDGLTP  179
            L    ++ +  FDV ++SGD+DL QL+  +  V+I+ KGV+++E +TP  + EK  GLTP
Sbjct  123  LDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEK-MGLTP  181

Query  180  KQIIDMKGLAGDASDNIPGVTKIGEKTAIKLLKQYGSVEGIYEHIDEMKQSKMKENLIND  239
            +Q+ID+K+L GD SDNIPGVTKIGEKT++KLL ++GS+EGIYEHID  K SKMKENLIND
Sbjct  182  NQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIND  241

Query  240  KEQAFLSKKLATINTSAPVDVSIDSLKYEGKNLDKLVPFYKEMDFNQFLSKLNIVEEEVK  299
            ++QAFLSK LATINT++P+ +++D + Y+G ++  L  FY EMDF Q+   L     +  
Sbjct  242  RDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEP  301

Query  300  MDDILFEVVHEFKEEMFTTDMALYVEMMGDNYHTEEIVGVAWGTEKKIYVTNDLSVFENR  359
            +  I ++ V +   ++F+++  +Y E + DNYH E I+G AWG   +IY + DLS++   
Sbjct  302  VAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLATD  361

Query  360  AFHSWITDPTRLKKVYDAKRTYVALNRYTGKTKGIDFDVLLGAYLLDTNEKSTDIEGIAA  419
            +F   +  P      YD KR+ V L++      +  +D  L+ YLL T E   ++  IA 
Sbjct  362  SFKQVFQKPI---ATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVE-DNELSTIAR  417

Query  420  HYGYNDIQSDEAVYGKGAKKGLPEEEELFFAHLARKVAAINALTPKLSQELADKNQEDLF  479
             +    ++ D++VYGKGAK+++P+ + L+  HLARKV  +    +++ + L+  +Q DL+
Sbjct  418  IFTDISLEEDDTVYGKGAKRAVPDKDVLL-EHLARKVKVLLDSKSQMLDKLTAHEQLDLY  476

Query  480  RKMELPLSIILAEMEISGIKVDATRLQEMKGEFSARLREIEQKIYEEAGEEFNLNSPKQL  539
            +++ELPL+ +LA MEI GIKV+ + LQ+M  +    +  + Q IY+ AG+EFN+NSPKQL
Sbjct  477  QNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQL  536

Query  540  GVILFEKMGLP--VIKKTKTGYSTAVDVLEQLREQAPIVEDILTYRQIAKIQSTYVEGLL  597
            G ILFEKM LP  + KKTKTGYSTAVDVLE+L   APIV  IL YRQI+K+QSTYV GL 
Sbjct  537  GSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQ  596

Query  598  KVIQSDGKVHTRYVQTLTQTGRLSSVDPNLQNIPIRLDEGRKIRQAFVPREKDWLIYSSD  657
              I +DGK+HTRYVQ LTQTGRLSSVDPNLQNIPIRL++GR IR+AF P + D ++ SSD
Sbjct  597  DYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSD  656

Query  658  YSQIELRVLAHISNDEHLKAAFLEGQDIHASTAMRVFGIEKAEDVTPNMRRQAKAVNFGI  717
            YSQIELRVLAHIS DEHL AAF EG DIH+STAMRVFGI+KA DVT+N RR+AKAVNFGI
Sbjct  657  YSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGI  716

Query  718  VYGISDYGLSQNLGISRKAAQQYIDTYFEKYPGVKEYMERIVREAKDQGYVETLYHRRRY  777
            VYGISD+GLS+NLGI+RK ++ YIDTYFE+YPG+K YME +VREAKD+GYVETL+ RRR 
Sbjct  717  VYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRE  776

Query  778  LPDINSRNYNIRSFAERTAINTPIQGSAADILKIAMIELDKRLKETGLQATMLLQVHDEL  837
            LPDINSRN+N+RSFAERTAIN+PIQGSAADILKIAMI+LDK L+  G++A MLLQVHDE+
Sbjct  777  LPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEI  836

Query  838  VFEVPEKELESLDKLVKEVMEQAVSLHVPLITDSSWGKTWYEAK  881
            V+EVP+ EL ++ KLVK+ ME AV L VPL  D S G++WYEAK
Sbjct  837  VLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

132) ENT_22130 in NC_021023


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  866 bits (3278),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 509/887 (58%), Positives = 697/887 (79%), Gaps = 15/887 (1%)

Query  2    TKKKLLLVDGNSVAFRAFFALHNSLERFKNKNGLHTNAIYAFNNMFENVMQKEMPTHVLV  61
             K+KLLL+DG+SVAFRAFFAL N ++RFKN +GLHTNAIY+F+ M++++M++  PTHVLV
Sbjct  3    NKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLV  62

Query  62   AFDAGKTTFRTEFYSEYKAGRSKTPGEFKEQMPYIRELLEGLGVKYYELPNYEADDIIGT  121
            AFDAGKTTFRTE Y++YKAGR+KTP+EF+EQ +YIRE+L +LG+ YYEL +YEADDIIGT
Sbjct  63   AFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGT  122

Query  122  LANKVDKDE--FDVVVLSGDRDLTQLATDTVKVDITVKGVSDIESYTPEHIAEKYDGLTP  179
            L +  ++ E  FDV ++SGD+DL QL+ +   V+I+ KGV+++E +TP  + EK  GLTP
Sbjct  123  LDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEK-MGLTP  181

Query  180  KQIIDMKGLAGDTSDNIPGVTKIGEKTAIKLLKQYGSVEGVYENIDEMKKSKMKENLIND  239
            +Q+ID+K+L GD SDNIPGVTKIGEKT++KLL ++GS+EG+YE+ID  K SKMKENLIND
Sbjct  182  NQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIND  241

Query  240  KEQAFLSKRLATIEVNAPVEVNVEDLAYEGKNLEKLVPFYKEMDFKQFLAKL--DITEEP  297
            ++QAFLSK LATI+  +P+ + ++D+ Y+G ++  L  FY EMDF Q+   L  ++ +EP
Sbjct  242  RDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEP  301

Query  298  VEMEDILFEVVEDQLTNEMFTDDMALYVEMMEDNYHTSPIVGLAWGNNKKIYTTNNLAVF  357
            V +  I ++ V + ++ ++F+ +  +Y E + DNYH  +I+G+AWG+  +IY++ +L+++
Sbjct  302  VAV--ISYQEVTN-VSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLL  358

Query  358  ESQPFIDWLMDETRKKNVYDAKRTYVALNRYVGKMTGIAFDVLLAAYLLDTNDNNADIEG  417
             +++F + +    +    YD KR+ V L++    + + ++D  LA YLL T ++N ++  
Sbjct  359  ATDSFKQVF---QKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDN-ELST  414

Query  418  VAQHYGYDAIQSDEAIYGKGAKKGLPEDEEVFFGHLARKIKAIQFLTSKLDSELTEKNQA  477
            +A+ +   +++ D+++YGKGAK+++P D +V++ HLARK+K +    S++   LT  +Q 
Sbjct  415  IARIFTDISLEEDDTVYGKGAKRAVP-DKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQL  473

Query  478  DLFYKMELPLSRILGDMEITGIRVDATRLKEMQVEFSERLKEIEEKIYAEAGEEFNLNSP  537
            DL+ ++ELPL+ +L+ MEI GI+V+ + L++M  +    +  + + IY  AG+EFN+NSP
Sbjct  474  DLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSP  533

Query  538  KQLGVILFEKMGLP--VIKKTKTGYSTAVDVLEQLKEQAPIVADILTYRQIAKIQSTYVE  595
            KQLG ILFEKM LP  + KKTKTGYSTAVDVLE+L   APIVA IL YRQI+K+QSTYV 
Sbjct  534  KQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVI  593

Query  596  GLLKVIQPDNKIHTRYVQTLTQTGRLSSVDPNLQNIPIRLEEGRKIREAFVPREDNWLIF  655
            GL   I +D KIHTRYVQ LTQTGRLSSVDPNLQNIPIRLE+GR IR AF P +++ +++
Sbjct  594  GLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLL  653

Query  656  SSDYSQIELRVLAHISNDEHLKEAFVEGQDIHASTAMRVFGVEKAEDVTPNMRRQAKAVN  715
            SSDYSQIELRVLAHIS DEHL  AF EG DIH+STAMRVFG++KA DVT+N RR+AKAVN
Sbjct  654  SSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVN  713

Query  716  FGIVYGISDYGLSQNLGITRKQAQQYIDTYFEKYPGVKQYMEEIVRDAKDKGYVETLYHR  775
            FGIVYGISD+GLS+NLGITRKQ++ YIDTYFE+YPG+K YME++VR+AKDKGYVETL+ R
Sbjct  714  FGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKR  773

Query  776  RRYLSDINSRNFNLRSFAERTAINTPIQGSAADILKIAMIEMARRLKEEKLQATMLLQVH  835
            RR L+DINSRNFN+RSFAERTAIN+PIQGSAADILKIAMI++ + L+   ++A MLLQVH
Sbjct  774  RRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVH  833

Query  836  DELVFEVPESELEQLNQLVKEVMEHAVSLHVPLITDSSWGKTWYEAK  882
            DE+V+EVP+ EL  +++LVK+ ME AV L VPL  D S G++WYEAK
Sbjct  834  DEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

133) EFD32_0689 in NC_018221


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  866 bits (3278),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 509/887 (58%), Positives = 697/887 (79%), Gaps = 15/887 (1%)

Query  2    TKKKLLLVDGNSVAFRAFFALHNSLERFKNKNGLHTNAIYAFNNMFENVMQKEMPTHVLV  61
             K+KLLL+DG+SVAFRAFFAL N ++RFKN +GLHTNAIY+F+ M++++M++  PTHVLV
Sbjct  3    NKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLV  62

Query  62   AFDAGKTTFRTEFYSEYKAGRSKTPGEFKEQMPYIRELLEGLGVKYYELPNYEADDIIGT  121
            AFDAGKTTFRTE Y++YKAGR+KTP+EF+EQ +YIRE+L +LG+ YYEL +YEADDIIGT
Sbjct  63   AFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGT  122

Query  122  LANKVDKDE--FDVVVLSGDRDLTQLATDTVKVDITVKGVSDIESYTPEHIAEKYDGLTP  179
            L +  ++ E  FDV ++SGD+DL QL+ +   V+I+ KGV+++E +TP  + EK  GLTP
Sbjct  123  LDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEK-MGLTP  181

Query  180  KQIIDMKGLAGDTSDNIPGVTKIGEKTAIKLLKQYGSVEGVYENIDEMKKSKMKENLIND  239
            +Q+ID+K+L GD SDNIPGVTKIGEKT++KLL ++GS+EG+YE+ID  K SKMKENLIND
Sbjct  182  NQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIND  241

Query  240  KEQAFLSKRLATIEVNAPVEVNVEDLAYEGKNLEKLVPFYKEMDFKQFLAKL--DITEEP  297
            ++QAFLSK LATI+  +P+ + ++D+ Y+G ++  L  FY EMDF Q+   L  ++ +EP
Sbjct  242  RDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEP  301

Query  298  VEMEDILFEVVEDQLTNEMFTDDMALYVEMMEDNYHTSPIVGLAWGNNKKIYTTNNLAVF  357
            V +  I ++ V + ++ ++F+ +  +Y E + DNYH  +I+G+AWG+  +IY++ +L+++
Sbjct  302  VAV--ISYQEVTN-VSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLL  358

Query  358  ESQPFIDWLMDETRKKNVYDAKRTYVALNRYVGKMTGIAFDVLLAAYLLDTNDNNADIEG  417
             +++F + +    +    YD KR+ V L++    + + ++D  LA YLL T ++N ++  
Sbjct  359  ATDSFKQVF---QKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDN-ELST  414

Query  418  VAQHYGYDAIQSDEAIYGKGAKKGLPEDEEVFFGHLARKIKAIQFLTSKLDSELTEKNQA  477
            +A+ +   +++ D+++YGKGAK+++P D +V++ HLARK+K +    S++   LT  +Q 
Sbjct  415  IARIFTDISLEEDDTVYGKGAKRAVP-DKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQL  473

Query  478  DLFYKMELPLSRILGDMEITGIRVDATRLKEMQVEFSERLKEIEEKIYAEAGEEFNLNSP  537
            DL+ ++ELPL+ +L+ MEI GI+V+ + L++M  +    +  + + IY  AG+EFN+NSP
Sbjct  474  DLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSP  533

Query  538  KQLGVILFEKMGLP--VIKKTKTGYSTAVDVLEQLKEQAPIVADILTYRQIAKIQSTYVE  595
            KQLG ILFEKM LP  + KKTKTGYSTAVDVLE+L   APIVA IL YRQI+K+QSTYV 
Sbjct  534  KQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVI  593

Query  596  GLLKVIQPDNKIHTRYVQTLTQTGRLSSVDPNLQNIPIRLEEGRKIREAFVPREDNWLIF  655
            GL   I +D KIHTRYVQ LTQTGRLSSVDPNLQNIPIRLE+GR IR AF P +++ +++
Sbjct  594  GLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLL  653

Query  656  SSDYSQIELRVLAHISNDEHLKEAFVEGQDIHASTAMRVFGVEKAEDVTPNMRRQAKAVN  715
            SSDYSQIELRVLAHIS DEHL  AF EG DIH+STAMRVFG++KA DVT+N RR+AKAVN
Sbjct  654  SSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVN  713

Query  716  FGIVYGISDYGLSQNLGITRKQAQQYIDTYFEKYPGVKQYMEEIVRDAKDKGYVETLYHR  775
            FGIVYGISD+GLS+NLGITRKQ++ YIDTYFE+YPG+K YME++VR+AKDKGYVETL+ R
Sbjct  714  FGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKR  773

Query  776  RRYLSDINSRNFNLRSFAERTAINTPIQGSAADILKIAMIEMARRLKEEKLQATMLLQVH  835
            RR L+DINSRNFN+RSFAERTAIN+PIQGSAADILKIAMI++ + L+   ++A MLLQVH
Sbjct  774  RRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVH  833

Query  836  DELVFEVPESELEQLNQLVKEVMEHAVSLHVPLITDSSWGKTWYEAK  882
            DE+V+EVP+ EL  +++LVK+ ME AV L VPL  D S G++WYEAK
Sbjct  834  DEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

134) polA in NC_019770


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  866 bits (3278),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 509/887 (58%), Positives = 697/887 (79%), Gaps = 15/887 (1%)

Query  2    TKKKLLLVDGNSVAFRAFFALHNSLERFKNKNGLHTNAIYAFNNMFENVMQKEMPTHVLV  61
             K+KLLL+DG+SVAFRAFFAL N ++RFKN +GLHTNAIY+F+ M++++M++  PTHVLV
Sbjct  3    NKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLV  62

Query  62   AFDAGKTTFRTEFYSEYKAGRSKTPGEFKEQMPYIRELLEGLGVKYYELPNYEADDIIGT  121
            AFDAGKTTFRTE Y++YKAGR+KTP+EF+EQ +YIRE+L +LG+ YYEL +YEADDIIGT
Sbjct  63   AFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGT  122

Query  122  LANKVDKDE--FDVVVLSGDRDLTQLATDTVKVDITVKGVSDIESYTPEHIAEKYDGLTP  179
            L +  ++ E  FDV ++SGD+DL QL+ +   V+I+ KGV+++E +TP  + EK  GLTP
Sbjct  123  LDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEK-MGLTP  181

Query  180  KQIIDMKGLAGDTSDNIPGVTKIGEKTAIKLLKQYGSVEGVYENIDEMKKSKMKENLIND  239
            +Q+ID+K+L GD SDNIPGVTKIGEKT++KLL ++GS+EG+YE+ID  K SKMKENLIND
Sbjct  182  NQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIND  241

Query  240  KEQAFLSKRLATIEVNAPVEVNVEDLAYEGKNLEKLVPFYKEMDFKQFLAKL--DITEEP  297
            ++QAFLSK LATI+  +P+ + ++D+ Y+G ++  L  FY EMDF Q+   L  ++ +EP
Sbjct  242  RDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEP  301

Query  298  VEMEDILFEVVEDQLTNEMFTDDMALYVEMMEDNYHTSPIVGLAWGNNKKIYTTNNLAVF  357
            V +  I ++ V + ++ ++F+ +  +Y E + DNYH  +I+G+AWG+  +IY++ +L+++
Sbjct  302  VAV--ISYQEVTN-VSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLL  358

Query  358  ESQPFIDWLMDETRKKNVYDAKRTYVALNRYVGKMTGIAFDVLLAAYLLDTNDNNADIEG  417
             +++F + +    +    YD KR+ V L++    + + ++D  LA YLL T ++N ++  
Sbjct  359  ATDSFKQVF---QKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDN-ELST  414

Query  418  VAQHYGYDAIQSDEAIYGKGAKKGLPEDEEVFFGHLARKIKAIQFLTSKLDSELTEKNQA  477
            +A+ +   +++ D+++YGKGAK+++P D +V++ HLARK+K +    S++   LT  +Q 
Sbjct  415  IARIFTDISLEEDDTVYGKGAKRAVP-DKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQL  473

Query  478  DLFYKMELPLSRILGDMEITGIRVDATRLKEMQVEFSERLKEIEEKIYAEAGEEFNLNSP  537
            DL+ ++ELPL+ +L+ MEI GI+V+ + L++M  +    +  + + IY  AG+EFN+NSP
Sbjct  474  DLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSP  533

Query  538  KQLGVILFEKMGLP--VIKKTKTGYSTAVDVLEQLKEQAPIVADILTYRQIAKIQSTYVE  595
            KQLG ILFEKM LP  + KKTKTGYSTAVDVLE+L   APIVA IL YRQI+K+QSTYV 
Sbjct  534  KQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVI  593

Query  596  GLLKVIQPDNKIHTRYVQTLTQTGRLSSVDPNLQNIPIRLEEGRKIREAFVPREDNWLIF  655
            GL   I +D KIHTRYVQ LTQTGRLSSVDPNLQNIPIRLE+GR IR AF P +++ +++
Sbjct  594  GLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLL  653

Query  656  SSDYSQIELRVLAHISNDEHLKEAFVEGQDIHASTAMRVFGVEKAEDVTPNMRRQAKAVN  715
            SSDYSQIELRVLAHIS DEHL  AF EG DIH+STAMRVFG++KA DVT+N RR+AKAVN
Sbjct  654  SSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVN  713

Query  716  FGIVYGISDYGLSQNLGITRKQAQQYIDTYFEKYPGVKQYMEEIVRDAKDKGYVETLYHR  775
            FGIVYGISD+GLS+NLGITRKQ++ YIDTYFE+YPG+K YME++VR+AKDKGYVETL+ R
Sbjct  714  FGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKR  773

Query  776  RRYLSDINSRNFNLRSFAERTAINTPIQGSAADILKIAMIEMARRLKEEKLQATMLLQVH  835
            RR L+DINSRNFN+RSFAERTAIN+PIQGSAADILKIAMI++ + L+   ++A MLLQVH
Sbjct  774  RRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVH  833

Query  836  DELVFEVPESELEQLNQLVKEVMEHAVSLHVPLITDSSWGKTWYEAK  882
            DE+V+EVP+ EL  +++LVK+ ME AV L VPL  D S G++WYEAK
Sbjct  834  DEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

135) polA in NC_004668


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  866 bits (3278),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 509/887 (58%), Positives = 697/887 (79%), Gaps = 15/887 (1%)

Query  2    TKKKLLLVDGNSVAFRAFFALHNSLERFKNKNGLHTNAIYAFNNMFENVMQKEMPTHVLV  61
             K+KLLL+DG+SVAFRAFFAL N ++RFKN +GLHTNAIY+F+ M++++M++  PTHVLV
Sbjct  3    NKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLV  62

Query  62   AFDAGKTTFRTEFYSEYKAGRSKTPGEFKEQMPYIRELLEGLGVKYYELPNYEADDIIGT  121
            AFDAGKTTFRTE Y++YKAGR+KTP+EF+EQ +YIRE+L +LG+ YYEL +YEADDIIGT
Sbjct  63   AFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGT  122

Query  122  LANKVDKDE--FDVVVLSGDRDLTQLATDTVKVDITVKGVSDIESYTPEHIAEKYDGLTP  179
            L +  ++ E  FDV ++SGD+DL QL+ +   V+I+ KGV+++E +TP  + EK  GLTP
Sbjct  123  LDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEK-MGLTP  181

Query  180  KQIIDMKGLAGDTSDNIPGVTKIGEKTAIKLLKQYGSVEGVYENIDEMKKSKMKENLIND  239
            +Q+ID+K+L GD SDNIPGVTKIGEKT++KLL ++GS+EG+YE+ID  K SKMKENLIND
Sbjct  182  NQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIND  241

Query  240  KEQAFLSKRLATIEVNAPVEVNVEDLAYEGKNLEKLVPFYKEMDFKQFLAKL--DITEEP  297
            ++QAFLSK LATI+  +P+ + ++D+ Y+G ++  L  FY EMDF Q+   L  ++ +EP
Sbjct  242  RDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEP  301

Query  298  VEMEDILFEVVEDQLTNEMFTDDMALYVEMMEDNYHTSPIVGLAWGNNKKIYTTNNLAVF  357
            V +  I ++ V + ++ ++F+ +  +Y E + DNYH  +I+G+AWG+  +IY++ +L+++
Sbjct  302  VAV--ISYQEVTN-VSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLL  358

Query  358  ESQPFIDWLMDETRKKNVYDAKRTYVALNRYVGKMTGIAFDVLLAAYLLDTNDNNADIEG  417
             +++F + +    +    YD KR+ V L++    + + ++D  LA YLL T ++N ++  
Sbjct  359  ATDSFKQVF---QKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDN-ELST  414

Query  418  VAQHYGYDAIQSDEAIYGKGAKKGLPEDEEVFFGHLARKIKAIQFLTSKLDSELTEKNQA  477
            +A+ +   +++ D+++YGKGAK+++P D +V++ HLARK+K +    S++   LT  +Q 
Sbjct  415  IARIFTDISLEEDDTVYGKGAKRAVP-DKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQL  473

Query  478  DLFYKMELPLSRILGDMEITGIRVDATRLKEMQVEFSERLKEIEEKIYAEAGEEFNLNSP  537
            DL+ ++ELPL+ +L+ MEI GI+V+ + L++M  +    +  + + IY  AG+EFN+NSP
Sbjct  474  DLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSP  533

Query  538  KQLGVILFEKMGLP--VIKKTKTGYSTAVDVLEQLKEQAPIVADILTYRQIAKIQSTYVE  595
            KQLG ILFEKM LP  + KKTKTGYSTAVDVLE+L   APIVA IL YRQI+K+QSTYV 
Sbjct  534  KQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVI  593

Query  596  GLLKVIQPDNKIHTRYVQTLTQTGRLSSVDPNLQNIPIRLEEGRKIREAFVPREDNWLIF  655
            GL   I +D KIHTRYVQ LTQTGRLSSVDPNLQNIPIRLE+GR IR AF P +++ +++
Sbjct  594  GLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLL  653

Query  656  SSDYSQIELRVLAHISNDEHLKEAFVEGQDIHASTAMRVFGVEKAEDVTPNMRRQAKAVN  715
            SSDYSQIELRVLAHIS DEHL  AF EG DIH+STAMRVFG++KA DVT+N RR+AKAVN
Sbjct  654  SSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVN  713

Query  716  FGIVYGISDYGLSQNLGITRKQAQQYIDTYFEKYPGVKQYMEEIVRDAKDKGYVETLYHR  775
            FGIVYGISD+GLS+NLGITRKQ++ YIDTYFE+YPG+K YME++VR+AKDKGYVETL+ R
Sbjct  714  FGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKR  773

Query  776  RRYLSDINSRNFNLRSFAERTAINTPIQGSAADILKIAMIEMARRLKEEKLQATMLLQVH  835
            RR L+DINSRNFN+RSFAERTAIN+PIQGSAADILKIAMI++ + L+   ++A MLLQVH
Sbjct  774  RRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVH  833

Query  836  DELVFEVPESELEQLNQLVKEVMEHAVSLHVPLITDSSWGKTWYEAK  882
            DE+V+EVP+ EL  +++LVK+ ME AV L VPL  D S G++WYEAK
Sbjct  834  DEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

136) polA in NC_017316


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  865 bits (3277),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 509/887 (58%), Positives = 698/887 (79%), Gaps = 15/887 (1%)

Query  2    TKKKLLLVDGNSVAFRAFFALHNSLERFKNKNGLHTNAIYAFNNMFENVMQKEMPTHVLV  61
             K+KLLL+DG+SVAFRAFFAL N ++RFKN +GLHTNAIY+F+ M++++M++  PTHVLV
Sbjct  3    NKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLV  62

Query  62   AFDAGKTTFRTEFYSEYKAGRSKTPGEFKEQMPYIRELLEGLGVKYYELPNYEADDIIGT  121
            AFDAGKTTFRTE Y++YKAGR+KTP+EF+EQ +YIRE+L +LG+ YYEL +YEADDIIGT
Sbjct  63   AFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGT  122

Query  122  LANKVDKDE--FDVVVLSGDRDLTQLATDTVKVDITVKGVSDIESYTPEHIAEKYDGLTP  179
            L +  ++ E  FDV ++SGD+DL QL+ +   V+I+ KGV+++E +TP  + EK  GLTP
Sbjct  123  LDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEK-MGLTP  181

Query  180  KQIIDMKGLAGDTSDNIPGVTKIGEKTAIKLLKQYGSVEGVYENIDEMKKSKMKENLIND  239
            +Q+ID+K+L GD SDNIPGVTKIGEKT++KLL ++GS+EG+YE+ID  K SKMKENLIND
Sbjct  182  NQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIND  241

Query  240  KEQAFLSKRLATIEVNAPVEVNVEDLAYEGKNLEKLVPFYKEMDFKQFLAKL--DITEEP  297
            ++QAFLSK LATI+  +P+ + ++D+ Y+G ++  L  FY EMDF Q+   L  ++ +EP
Sbjct  242  RDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEP  301

Query  298  VEMEDILFEVVEDQLTNEMFTDDMALYVEMMEDNYHTSPIVGLAWGNDKKIYTTNNLAVF  357
            V +  I ++ V + ++ ++F+ +  +Y E + DNYH  +I+G+AWG++ +IY++ +L+++
Sbjct  302  VAV--ISYQEVTN-VSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLL  358

Query  358  ESQPFIDWLMDETRKKNVYDAKRTYVALNRYVGKMTGIAFDVLLAAYLLDTNDNNADIEG  417
             +++F + +    +    YD KR+ V L++    + + ++D  LA YLL T ++N ++  
Sbjct  359  ATDSFKQVF---QKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDN-ELST  414

Query  418  VAQHYGYDAIQSDEAIYGKGAKKGLPEDEEVFFGHLARKIKAIQFLTSKLDSELTEKNQA  477
            +A+ +   +++ D+++YGKGAK+++P D +V++ HLARK+K +    S++   LT  +Q 
Sbjct  415  IARIFTDISLEEDDTVYGKGAKRAVP-DKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQL  473

Query  478  DLFYKMELPLSRILGDMEITGIRVDATRLKEMQVEFSERLKEIEEKIYAEAGEEFNLNSP  537
            DL+ ++ELPL+ +L+ MEI GI+V+ + L++M  +    +  + + IY  AG+EFN+NSP
Sbjct  474  DLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSP  533

Query  538  KQLGVILFEKMGLP--VIKKTKTGYSTAVDVLEQLKEQAPIVADILTYRQIAKIQSTYVE  595
            KQLG ILFEKM LP  + KKTKTGYSTAVDVLE+L   APIVA IL YRQI+K+QSTYV 
Sbjct  534  KQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVI  593

Query  596  GLLKVIQPDNKIHTRYVQTLTQTGRLSSVDPNLQNIPIRLEEGRKIREAFVPREDNWLIF  655
            GL   I +D KIHTRYVQ LTQTGRLSSVDPNLQNIPIRLE+GR IR AF P +++ +++
Sbjct  594  GLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLL  653

Query  656  SSDYSQIELRVLAHISNDEHLKEAFVEGQDIHASTAMRVFGVEKAEDVTPNMRRQAKAVN  715
            SSDYSQIELRVLAHIS DEHL  AF EG DIH+STAMRVFG++KA DVT+N RR+AKAVN
Sbjct  654  SSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVN  713

Query  716  FGIVYGISDYGLSQNLGITRKQAQQYIDTYFEKYPGVKQYMEEIVRDAKDKGYVETLYHR  775
            FGIVYGISD+GLS+NLGITRKQ++ YIDTYFE+YPG+K YME++VR+AKDKGYVETL+ R
Sbjct  714  FGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKR  773

Query  776  RRYLSDINSRNFNLRSFAERTAINTPIQGSAADILKIAMIEMARRLKEEKLQATMLLQVH  835
            RR L+DINSRNFN+RSFAERTAIN+PIQGSAADILKIAMI++ + L+   ++A MLLQVH
Sbjct  774  RRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVH  833

Query  836  DELVFEVPESELEQLNQLVKEVMEHAVSLHVPLITDSSWGKTWYEAK  882
            DE+V+EVP+ EL  +++LVK+ ME AV L VPL  D S G++WYEAK
Sbjct  834  DEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

137) ECBG_00868 in NC_020995


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  861 bits (3262),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 522/885 (59%), Positives = 684/885 (78%), Gaps = 14/885 (1%)

Query  3    KNKLLLVDGNSVAFRAFFALHNSLERFKNANGLHTNAIYAFHTMFENVMAKEQPTHVLVA  62
            KNKLLL+DG+SVAFRAFFAL N ++RFKN +GLHTNAIY+FH M++++M + +PTHVLVA
Sbjct  4    KNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVA  63

Query  63   FDAGKTTFRTAMYEDYKGGRSKTPGEFKEQMPYIRELINALGVQYYELDNYEADDIIGTL  122
            FDAGKTTFRT MY DYK+GR+KTP+EF+EQ +YIRE++ ALG+ YYEL++YEADDIIGTL
Sbjct  64   FDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTL  123

Query  123  ANKVDKE--LFDVVVLSGDRDLTQLATEHVKVDITVKGVSEIESYTPAHVAEKYDGLTPL  180
             +  ++    FDV ++SGD+DL QL+ E+  V+I+ KGV+E+E +TPA + EK  GLTP 
Sbjct  124  DKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEK-MGLTPN  182

Query  181  QIIDMKGLAGDASDNIPGVTKIGEKTAIKLLKEYGSVEGIYEHIDEMKKSKMKENLINDR  240
            Q+ID+K+L GD SDNIPGVTKIGEKT++KLL E+GS+EGIYEHID  K SKMKENLINDR
Sbjct  183  QFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDR  242

Query  241  EIAFLSKQLATIDVDAPIEVDVDKLKYEGKDLEKLVPFYQEMNFNSFLEKL--QITAEPV  298
            + AFLSK LATI+  +PI +++D + Y+G D+  L  FY+EM+F  +   L  Q+  EPV
Sbjct  243  DQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEPV  302

Query  299  EMEDILFSVVEEVTEDMFQGDTALYVEMMGDNYHLEDIVGVAWGNQEKIYVSNREELFES  358
             +  I +  V +V+ D+F ++  +Y E + DNYH E I+G AWG+ E+IY S    L+ +
Sbjct  303  AV--ISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLAT  360

Query  359  PVFTNWLKDEERKKFVYDAKRTYVALNRYTTAPKGIAFDVLLAAYLLDTNDTNNDIAGVA  418
              F + +   ++    YD KR+ V L++      + ++D  LA YLL T + +N+++ +A
Sbjct  361  DSFKQVF---QKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVE-DNELSTIA  416

Query  419  AHYGYDAIQSDEAIYGKGAKKGLPADEEDFFAHLARKVAAITNLTPKLTEELAAKNQTAL  478
              +   +++ D+++YGKGAK+++P D + ++ HLARKV  + +  +++ + L+A +Q  L
Sbjct  417  RIFTDISLEEDDTVYGKGAKRAVP-DKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDL  475

Query  479  FEEMELPLSMILADMEITGIKVDASRLHQMKGEFAQRLHEIEEKIYAEAGETFNLNSPKQ  538
            ++++ELPL+ +LA MEI GIKV+ + L++M  +    ++ + + IY  AG+ FN+NSPKQ
Sbjct  476  YQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQ  535

Query  539  LGVILFEKMGLP--VIKKTKTGYSTAVDVLEQLKEQAPIVEDILTYRQIAKIQSTYVEGL  596
            LG ILFEKM LP  + KKTKTGYSTAVDVLE+L   APIV  IL YRQI+K+QSTYV GL
Sbjct  536  LGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGL  595

Query  597  LKVIQGDGKVHTRYVQTLTQTGRLSSVDPNLQNIPIRLEEGRKIREAFVPREADWVIYSS  656
               I +DGK+HTRYVQ LTQTGRLSSVDPNLQNIPIRLE+GR IR AF P + D V+ SS
Sbjct  596  QDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSS  655

Query  657  DYSQIELRVLAHISDDTHLKEAFIEGQDIHSSTAMRVFGIEKAEDVTPNMRRQAKAVNFG  716
            DYSQIELRVLAHIS+D HL  AF EG DIH+STAMRVFGI+KA DVT+N RR+AKAVNFG
Sbjct  656  DYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFG  715

Query  717  IVYGISDYGLSQNLGITRKAAQQYIDTYFEKYPGVKTYMEDVVREAKDKGYVETLYHRRR  776
            IVYGISD+GLS+NLGITRK ++ YIDTYFE+YPG+K+YME+VVREAKDKGYVETL+ RRR
Sbjct  716  IVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRR  775

Query  777  YLPDINSRNFNIRTFAERTAINTPIQGSAADILKIAMIDLVKRLKEEKLAATMLLQVHDE  836
             LPDINSRNFN+R+FAERTAIN+PIQGSAADILKIAMI+L K L+   + A MLLQVHDE
Sbjct  776  ELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDE  835

Query  837  LVFEVPESELPRLDALVKEVMEQAVALHVPLLTDSNWGKTWYDAK  881
            +V+EVP+ EL  +  LVK+ ME AV L VPL  D + G++WY+AK
Sbjct  836  IVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

138) polA in NC_016052


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  849 bits (3215),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 497/885 (57%), Positives = 684/885 (78%), Gaps = 12/885 (1%)

Query  2    AKNKLLLVDGNSVAFRAFYALHSSLERFKNPSGLHTNAIYAFNLMFENVMEKEKPSHVLV  61
             KNKLLL+DG+SVAFRAF+AL + ++RFKN SGLHTNAIY+F+LM++++M + +P+HVLV
Sbjct  3    NKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLV  62

Query  62   AFDAGKTTFRNEMYEDYKGGRAKTPGELNEQLPYIRELINGLGISYYELKNYEADDIIGT  121
            AFDAGKTTFR EMY DYK+GRAKTP+E+ EQ++YIRE++ +LGI+YYEL +YEADDIIGT
Sbjct  63   AFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGT  122

Query  122  LAEQVDKDK--FDVTILTGDRDLTQLATDDVKVAITKKGVSDTEDYTPEHIAEKYDGLKP  179
            L    ++    FDVTI++GD+DL QL+ ++  V I+KKGV++ E++TP  + EK  GL P
Sbjct  123  LDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEK-MGLTP  181

Query  180  KQIIDMKGLAGDSSDNIPGVTKIGDKTAIKLLNQYDSVEGVYEHIDEMKQSKMKENLIND  239
            +Q+ID+K+L GD SDNIPGVTKIG+KT++KLL++++S+EG+YEHID  K SKMKENLIND
Sbjct  182  NQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIND  241

Query  240  KETALLSKKLATINISAPIDVSIDSLKYEGSDLDKLVPFYKEMNFRTFLDNLDVGEEENK  299
            ++ A+LSK LATIN ++PI +++D + Y+G+D+  L  FY EM+F  +   L     ++ 
Sbjct  242  RDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEP  301

Query  300  MEDILFEVVDEPTEEMFTDEMALYVEMLGENYHVEDIVGVVWGNDKKIYVTKSDKIFENK  359
            +  I ++ V + + ++F+ E  +Y E L +NYH E I+G  WG++ +IY +    ++   
Sbjct  302  VAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLATD  361

Query  360  AFKNWLTDKSRGKRVYNAKSTQVALNRY-IALPEGFSFDVLVAAYLLDNTDNTDDIAGIC  418
            +FK+ +    +    Y+ K ++V L++  I L    S+D  +A YLL   ++ ++++ I 
Sbjct  362  SFKQVF---QKPIATYDFKRSKVLLSHLGIELVAP-SYDARLANYLLSTVED-NELSTIA  416

Query  419  AHYDYQDIQSDVAVYGKGAKKGLPEDDETFFAHLARKIKAIQWLTPKLEGELKDKNQLDL  478
              +    ++ D +VYGKGAK+++P+ D  ++ HLARK+K +    +++ + L   +QLDL
Sbjct  417  RIFTDISLEEDDTVYGKGAKRAVPDKD-VLLEHLARKVKVLLDSKSQMLDKLTAHEQLDL  475

Query  479  YKNLEAPISSILAEMEITGITVDAQRLNQMKDEFAQSLQKIEEKIFEQAGEKFNINSPKQ  538
            Y+N+E P++++LA MEI GI V+   L++M ++    ++ + + I++ AG+ FNINSPKQ
Sbjct  476  YQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQ  535

Query  539  LGHILFEKMNLP--VIKKTKTGYSTAVDVLEQLKDKSPIVENILKYRQIAKIQSTYVEGL  596
            LG ILFEKM+LP  + KKTKTGYSTAVDVLE+L   +PIV +IL YRQI+K+QSTYV GL
Sbjct  536  LGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGL  595

Query  597  LKVILQDGKVHTRYLQTLTQTGRLSSVDPNLQNIPIRLEEGRKIRQAFVPQKHDWVIYSS  656
               IL DGK+HTRY+Q LTQTGRLSSVDPNLQNIPIRLE+GR IR+AF P  +D V+ SS
Sbjct  596  QDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSS  655

Query  657  DYSQIELRVLAHVSKDEHLQEAFNENQDIHASTAMRVFDIEKPEDVTANIRRQAKAVNFG  716
            DYSQIELRVLAH+S DEHL  AFNE  DIH+STAMRVF+I+K+ DVTAN RR+AKAVNFG
Sbjct  656  DYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFG  715

Query  717  IVYGISDYGLSQNLGISRKEAKNYIDTYFERYPGVKKYMNDSVEQAKEKGFAETLYHRRR  776
            IVYGISD+GLS+NLGI+RK++K+YIDTYFERYPG+K YM++ V +AK+KG+ ETL+ RRR
Sbjct  716  IVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRR  775

Query  777  YLEDINSRNFNLRSFAERTAINSPIQGSAADILKIAMIELDKQLKEKQLETNMLLQVHDE  836
             L DINSRNFN+RSFAERTAINSPIQGSAADILKIAMI+LDK L+   + ++MLLQVHDE
Sbjct  776  ELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDE  835

Query  837  LVFEVPESELKTLDQLVKEVMENAVHLDVPLITESSWGKTWYDAK  881
            +V+EVP+ EL ++ +LVK+ ME AV+L VPL  + S G++WY+AK
Sbjct  836  IVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

139) MPTP_1619 in NC_015516


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  842 bits (3187),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 501/890 (57%), Positives = 681/890 (77%), Gaps = 16/890 (1%)

Query  2    TKKKLLLVDGNSVAFRAFFALHNSLERFKNQNGLHTNAIYAFNTMFENVMAKEEPTHVLV  61
             K+KLLL+DG+SVAFRAFFAL N ++RFKN++GLHTNAIY+F+ M++++M +  PTHVLV
Sbjct  3    NKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLV  62

Query  62   AFDAGKTTFRNAMYEDYKAGRAKTPDEFREQMPYIKELLEGLGVKHYELANYEADDIIGT  121
            AFDAGKTTFR  MY DYKAGRAKTPDEFREQ +YI+E+L +LG+  YEL +YEADDIIGT
Sbjct  63   AFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGT  122

Query  122  LATKVPKEE--YDVVILSGDRDLTQLATDTIKVDITVKGVSDIESCTPEYMFEKYDGLCP  179
            L     + E  +DV I+SGD+DL QL+ +   V+I+ KGV+++E  TP Y+ EK  GL P
Sbjct  123  LDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEK-MGLTP  181

Query  180  QQIIDIKGLAGDASDNIPGVTKVGEKTAIKLLKEYGSVEGVYNHIDEMKTSKLKENLIRD  239
            +Q+ID+K+L GD SDNIPGVTK+GEKT++KLL E+GS+EG+Y+HID  KTSK+KENLI D
Sbjct  182  NQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIND  241

Query  240  KEKAFLSKQLATIDTDAPVNVEIDQLVYHGKNLDKLVPFYREMNFKQFLGKLNLDTKTEE  299
            +++AFLSK LATI+T +P+ + +D++VY+G ++  L  FY EM+F Q    L+ +  ++ 
Sbjct  242  RDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQ----LKKGLASQM  297

Query  300  AEEEVALTKIAFQVVDTFKPEMFQGDMALYVEMLEDNYHLSPIIGIAWGNKQTIYVTENL  359
            ++E VA+  I++Q V    +++F ++  +Y E L DNYH  +IIG+AWG+ + IY + +L
Sbjct  298  PQEPVAV--ISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDL  355

Query  360  ALFEEQAFIDWLFDETCQKQVYDAKRTYTALNRYVGKMQGISFDILLAAYLLNTNDTNTD  419
            +L+  ++F + +F+       YD KR+   L++    + + S+D  LA YLL+T + + +
Sbjct  356  SLLATDSFKQ-VFQKPIA--TYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVE-DNE  411

Query  420  IECVARQYGYTDIQSDEAVYDRGAKKKVPQEKEIFYNHLAHKIKAIEYLSEKLAADLVEK  479
            +  +AR +    ++ D++VY++GAK+ VP +K+++ +HLA+K+K +     ++   L   
Sbjct  412  LSTIARIFTDISLEEDDTVYGKGAKRAVP-DKDVLLEHLARKVKVLLDSKSQMLDKLTAH  470

Query  480  NQANLFSEMELPLSRILADMEITGIHVDAHRLEEMQGEFSDQLKAIEQKIYTEAGEEFNI  539
            +Q +L+ ++ELPL+ +LA MEI GI V+   L++M  +    + A+ Q IY  AG+EFNI
Sbjct  471  EQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNI  530

Query  540  NSPKQLGVILFEKMGLP--VIKKTKTGYSTAVDVLEQLKERAPIVEDILIYRQIAKIQST  597
            NSPKQLG ILFEKM LP  + KKTKTGYSTAVDVLE+L   APIV  IL YRQI+K+QST
Sbjct  531  NSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQST  590

Query  598  YVEGLLKVIQPDHKVHTRYLQTLTQTGRLSSVDPNLQNIPIRLEEGRKIRQAFIPREKDW  657
            YV GL   I +D K+HTRY+Q LTQTGRLSSVDPNLQNIPIRLE+GR IR+AF P + D 
Sbjct  591  YVIGLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDA  650

Query  658  LIYSSDYSQIELRVLAHISNDEHLKAAFLEQQDIHASTAMRVFNLSSPEEVTPNMRRQAK  717
            ++ SSDYSQIELRVLAHIS DEHL AAF E  DIH+STAMRVF +  + +VT+N RR+AK
Sbjct  651  VLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAK  710

Query  718  AVNFGIVYGISDYGLSKNLEISRQQAQQYIDTYFNKYPSVKTYMEEIVREAKDKGYVETL  777
            AVNFGIVYGISD+GLS+NL I+R+Q++ YIDTYF++YP++K+YME++VREAKDKGYVETL
Sbjct  711  AVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETL  770

Query  778  YHRRRYLKDINSRNYNLRSFAERTAINTPIQGSAADILKIAMIQMDRRLKEENIQATMLL  837
            + RRR L DINSRN+N+RSFAERTAIN+PIQGSAADILKIAMI++D+ L+   ++A MLL
Sbjct  771  FKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLL  830

Query  838  QVHDELVFEVPAAELEKLDKIVKEVMEKCVSLTVPLIADSNWGKTWYEAK  887
            QVHDE+V+EVP  EL  + K+VK+ ME  V L+VPL  D + G++WYEAK
Sbjct  831  QVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

140) MPD5_0433 in NC_016938


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  840 bits (3181),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 500/890 (57%), Positives = 680/890 (77%), Gaps = 16/890 (1%)

Query  2    TKKKLLLVDGNSVAFRAFFALHNSLERFKNQNGLHTNAIYAFNTMFENVMAKEEPTHVLV  61
             K+KLLL+DG+SVAFRAFFAL N ++RFKN++GLHTNAIY+F+ M++++M +  PTHVLV
Sbjct  3    NKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLV  62

Query  62   AFDAGKTTFRNAMYEDYKAGRAKTPDEFREQMPYIKELLEGLGVKHYELANYEADDIIGT  121
            AFDAGKTTFR  MY DYKAGRAKTPDEFREQ +YI+E+L +LG+  YEL +YEADDIIGT
Sbjct  63   AFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGT  122

Query  122  LATKVPKEE--YDVVILSGDRDLTQLATDTIKVDITVKGVSDIESCTPEYMFEKYDGLCP  179
            L     + E  +DV I+SGD+DL QL+ +   V+I+ KGV+++E  TP Y+ EK  GL P
Sbjct  123  LDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEK-MGLTP  181

Query  180  QQIIDIKGLAGDASDNIPGVTKVGEKTAIKLLKEYGSVEGVYNHIDEMKTSKLKENLIRD  239
            +Q+ID+K+L GD SDNIPGVTK+GEKT++KLL E+GS+EG+Y+HID  KTSK+KENLI D
Sbjct  182  NQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIND  241

Query  240  KEKAFLSKQLATIDTDAPVNVEIDQLVYHGKNLDKLVPFYREMNFKQFLGKLNLDTKTEE  299
            +++AFLSK LATI+T +P+ + +D++VY+G ++  L  FY EM+F Q    L+ +  ++ 
Sbjct  242  RDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQ----LKKGLASQM  297

Query  300  AEEEVALTKIAFQVVDTFKPEMFQGDMALYVEMLEDNYHLSPIIGIAWGNKQTIYVTENL  359
            ++E VA+  I++Q V    +++F ++  +Y E L DNYH  +IIG+AWG+ + IY + +L
Sbjct  298  PQEPVAV--ISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDL  355

Query  360  ALFEEQAFIDWLFDETCQKQVYDAKRTYTALNRYVGKMQGISFDILLAAYLLNTNDTNTD  419
            +L+  ++F + +F+       YD KR+   L++    + + S+D  LA YLL+T + + +
Sbjct  356  SLLATDSFKQ-VFQKPIA--TYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVE-DNE  411

Query  420  IECVARQYGYTDIQSDEAVYDRGAKKKVPQEKEIFYNHLAHKIKAIEYLSEKLAADLVEK  479
            +  +AR +    ++ D++VY++GAK+ VP +K+++ +HLA+K+K +     ++   L   
Sbjct  412  LSTIARIFTDISLEEDDTVYGKGAKRAVP-DKDVLLEHLARKVKVLLDSKSQMLDKLTAH  470

Query  480  NQANLFSEMELPLSRILADMEITGIHVDAHRLEEMQGEFSDQLKAIEQKIYTEAGEEFNI  539
            +Q +L+ ++ELPL+ +LA MEI GI V+   L++M  +    + A+ Q IY  AG+EFNI
Sbjct  471  EQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNI  530

Query  540  NSPKQLGVILFEKMGLP--VIKKTKTGYSTAVDVLEQLKERAPIVEDILIYRQIAKIQST  597
            NSPKQLG ILFEKM LP  + KKTKTGYSTAVDVLE+L   APIV  IL YRQI+K+QST
Sbjct  531  NSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQST  590

Query  598  YVEGLLKVIQPDHKVHTRYLQTLTQTGRLSSVDPNLQNIPIRLEEGRKIRQAFIPREKDW  657
            YV GL   I +D K+HTRY+Q LTQTGRLSSVDPNLQNIPIRLE+GR IR+AF P + D 
Sbjct  591  YVIGLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDA  650

Query  658  LIYSSDYSQIELRVLAHISNDEHLKAAFLEQQDIHASTAMRVFNLSSPEEVTPNMRRQAK  717
            ++ SSDYSQIELRVLAHIS DEHL AAF E  DIH+STAMRVF +  + +VT+N RR+AK
Sbjct  651  VLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAK  710

Query  718  AVNFGIVYGISDYGLSKNLEISRQQAQQYIDTYFNKYPSVKTYMEEIVREAKDKGYVETL  777
            AVNFGIVYGISD+GLS+NL I+R+Q++ YIDTYF++YP++K+YME++VREAKDKGYVETL
Sbjct  711  AVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETL  770

Query  778  YHRRRYLKDINSKNYNLRSFAERTAINTPIQGSAADILKIAMIQMDRRLKEENMQATMLL  837
            + RRR L DINS+N+N+RSFAERTAIN+PIQGSAADILKIAMI++D+ L+    +A MLL
Sbjct  771  FKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLL  830

Query  838  QVHDELVFEVPAAELEKLDKIVKEVMEKCVSLTVPLIADSNWGKTWYEAK  887
            QVHDE+V+EVP  EL  + K+VK+ ME  V L+VPL  D + G++WYEAK
Sbjct  831  QVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

141) polA in NC_019425


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  839 bits (3175),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 518/890 (59%), Positives = 691/890 (78%), Gaps = 14/890 (1%)

Query  1    MTKKNKLLLIDGSSIAFRAFYAIPGSLDRFMNKNGLHTNALFSFHRMLDNEMKKEQPTHV  60
            M +KNKLLLIDGSS+AFRAF+A+   +DRF N +GLHTNA+++FH MLD+ MK+ +PTHV
Sbjct  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60

Query  61   LVAFDAGKTTFRNAFYDAYKDGRQKTPGEFKEQMPYLRDLLEGFGIPHYELDNYEADDII  120
            LVAFDAGKTTFR   Y  YK GR KTP+EF+EQ +Y+R++L ++GI+ YEL++YEADDII
Sbjct  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120

Query  121  GTLATvvdpnefd--vvvvSGDRDLTQLAKENVRVDITIKGVSEIEENTPAYLMEKYGIE  178
            GTL  + +  E    V +VSGD+DL QL+ EN  V+I+ KGV+E+EE TPAYLMEK G+ 
Sbjct  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180

Query  179  PHQIIDMKGLAGDSSDNIPGVTNIGEKTALKLLHEFGSVEGVYENIDGMKPSKRKENLIN  238
            P+Q+ID+K+L GD SDNIPGVT+IGEKT+LKLLHEFGS+EG+YE+IDG K SK KENLIN
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  239  DKEQALLSKKLATIEVDAPLEIKVDELLYTGKDVGKLIEFYKEMDFKSFLKDLDTTEYDE  298
            D++QA+LSK LATI+  +P+ I +D+++Y G DV+ L +FY EMDF  + K+L +   +E
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQE  300

Query  299  ENKIEKAEIIFEFVTELKADMFGPIGGLYVEMLTDNYHTAEIVGLSWSNGEKIYVAEPDV  358
               +    I ++ VT++ AD+F++ + +Y E L DNYH   I+G++W++GE+IY +    
Sbjct  301  PVAV----ISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLS  356

Query  359  ALASPIFQEWAKDPENKKQVFDAKRTVVALQRYDTTLEGVDFDVLLASYILNTNDNSKDL  418
             LA+  F++  + P      +D KR+ V L + +  L +  +D  LA+Y+L+T +++ +L
Sbjct  357  LLATDSFKQVFQKPIA---TYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDN-EL  412

Query  419  AEVAMEHDYYEVAADESIYGKGAKLAIPEDASVLNEHLARKIKAIEVLSIKLKQELIDSE  478
            + +A       +  D+++YGKGAK A+P+   VL EHLARK+K +     ++ + L   E
Sbjct  413  STIARIFTDISLEEDDTVYGKGAKRAVPDK-DVLLEHLARKVKVLLDSKSQMLDKLTAHE  471

Query  479  QTALFYEMELPLSMVLAEMEMTGIKVNANRLLEMKAEFAIRLTDIENRIYEEAGETFNIN  538
            Q  L+ ++ELPL+ VLA ME+ GIKVN   L +M  +  + +  + + IY+ AG+ FNIN
Sbjct  472  QLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNIN  531

Query  539  SPKQLGVILFEKMQLP--VIKKTKTGYSTAVDVLEQLRPQAPIVDDILHYRQIAKIQSTY  596
            SPKQLG ILFEKMQLP  + KKTKTGYSTAVDVLE+L P APIV  IL+YRQI+K+QSTY
Sbjct  532  SPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTY  591

Query  597  VEGLLKVINGNTGKVHTRYVQTLTQTGRLSSVDPNLQNIPIRLEEGRKIRQAFVPSHEGW  656
            V GL   I ++ GK+HTRYVQ LTQTGRLSSVDPNLQNIPIRLE+GR IR+AF PSHE+ 
Sbjct  592  VIGLQDYILAD-GKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDA  650

Query  657  KIFASDYSQIELRVLADISNDQHLKEAFLEGQDIHSSTAMRVFGIEKAEDVTGNMRRQAK  716
             +++SDYSQIELRVLA+IS D+HL  AF EG DIH+STAMRVFGI+KA DVT+N RR+AK
Sbjct  651  VLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAK  710

Query  717  AVNFGIVYGISDYGLSQNLGITRKEAQTFIDTYFEKYPGVKQYMSDIVREAKDKGYVETL  776
            AVNFGIVYGISD+GLS+NLGITRK+++++IDTYFE+YPG+K YM ++VREAKDKGYVETL
Sbjct  711  AVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETL  770

Query  777  FHRRRFLKDINSRNFNLRSFAERTAMNTPIQGSAADIIKVAMIQMDRRLKAENLKTKMLL  836
            F RRR L DINSRNFN+RSFAERTA+N+PIQGSAADI+K+AMI++D+ L+A  +++KMLL
Sbjct  771  FKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLL  830

Query  837  QVHDELIFEAPEEEIAILEKLVPEVMESAVKLNVPLKVDSSYGDSWYDAK  886
            QVHDE+++E P++E++ + KLV + ME+AV L VPL VD S G+SWY+AK
Sbjct  831  QVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

142) polA in NC_012984


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  829 bits (3138),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 512/885 (58%), Positives = 691/885 (79%), Gaps = 14/885 (1%)

Query  3    KKLLLIDGNSVAFRAFFALHSQLERFVNPDGLHTNAIYGFNTMLDHMIKAVEPTDMLVAF  62
            +KLLLIDG+SVAFRAFFAL +Q++RF N  GLHTNAIYGF+ MLDHM+K V PT++LVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  63   DAGKTTFRTAMYDNYKGGRAKTPSEFSEQMPYIKQLLDAYGIKHYELKDYEADDIIGTLA  122
            DAGKTTFRT MY +YK+GRAKTP EF EQ +YI+++L A GI  YEL +YEADDIIGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  123  AQADQTG--YTTTVVTGDRDLTQLTTEHTTVAVTVKGVSEVEHYTPAHVEEKLGITPAQI  180
              A++T   +  T+V+GD+DL QLT E+T V ++ KGV+E E++TPA + EK+G+TP Q+
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  181  IDMKGLTGDTSDNYPGVTKVGEKTALKLLKQYGTMEGIYENIDAMKQSKMKEHLIEDREQ  240
            ID+K+L GD SDN PGVTK+GEKT+LKLL ++G++EGIYE+ID+ K SKMKE+LI+DR+Q
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRDQ  244

Query  241  AAQAKVLATIKRDAPIDVQLADLSYDGPDLDQLAAFYQKMDFQSFLKKLHLQ-SDEPATP  299
            A  +K LATI+  +PI + L D+ Y+GPD+  L+ FY+ MDF  + K L  Q ++EP + 
Sbjct  245  AFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEPVAV  304

Query  300  IDYTVLTKANLTELQQFTDHVDFYLEMPTPNYHTSAFAGFAIGADDHWYISRDVELLMQP  359
            I Y  +T+ + ++L  F+ +  FY+E    NYH  A+ GFA G +++ Y S D+ LL   
Sbjct  305  ISYQEVTNVS-ADL--FSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLATD  361

Query  360  TVADLLSSTTITKDVFDMKRTTVGLNRLGIQLGKVDFDLLLVSYLLDTNDNSNDLGSLAE  419
            +  +++     T   +D KR+ V L++LGI+L    +D  L +YLL T ++ N+L+++A 
Sbjct  362  SFKQVFQKPIAT---YDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NELSTIAR  417

Query  420  QHGYTDLPSDETVYGKGVKRAIPEDDDVFFSHLARKLAAIASLKPQLLKELAANEQDQLY  479
                  L  D+TVYGKG KRA+P D DV++ HLARK+  +   K+Q+L  L+A+EQ +LY
Sbjct  418  IFTDISLEEDDTVYGKGAKRAVP-DKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLY  476

Query  480  DDIEKPMANVLAQMEIAGITVDSSRLKAMGSQFTERLSEIEQTIYQEAGEEFNINSPKQL  539
            ++IE P+ANVLA+MEI GI V+ + L+ M+ Q    +  + Q IY+ AG+EFNINSPKQL
Sbjct  477  QNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQL  536

Query  540  GHILFEEMKLP--VIKKTKTGYSTAVDVLEKLAPEAPIVANILQYRQISKIQSTYVVGLL  597
            G ILFE M+LP  + KKTKTGYSTAVDVLE+LAP APIVA+IL+YRQI+K+QSTYV+GL 
Sbjct  537  GSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQ  596

Query  598  DAIHSADQKVHTRYLQTLTQTGRLSSVDPNLQNIPVRLEEGRKIRQAFVPSHEGWQIFSS  657
            D I  AD K+HTRY+Q LTQTGRLSSVDPNLQNIP+RLE+GR IR+AF PSHE+  ++SS
Sbjct  597  DYIL-ADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSS  655

Query  658  DYSQIELRVLAHITDDENMQAAFKAGDDIHAATAMRIFHLNSAEEVTPNIRRQAKAVNFG  717
            DYSQIELRVLAHI++DE++ AAF+ G DIH++TAMR+F ++ A +VT+N RR+AKAVNFG
Sbjct  656  DYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFG  715

Query  718  IVYGISDYGLSQNIGITRKQARSFIDAYFKEYPGVKKYMDEIVQTAKKQGYVETISHRRR  777
            IVYGISD+GLS+N+GITRKQ++S+ID+YF  YPG+K YM+++V+ AK +GYVET+  RRR
Sbjct  716  IVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRR  775

Query  778  YLPDINSKSFNQRSFAERTAMNTPIQGSaadiikiamikmqdkLQAAGLKATMLLQVHDE  837
             LPDINS++FN RSFAERTA+N+PIQGSAADI+KIAMI+++  LQA+G++A MLLQVHDE
Sbjct  776  ELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDE  835

Query  838  LIFEAPKEEIPVLEKLVPSVMDSAVQLAVPLKVESHYGDTWYDAK  882
            +++E P++E+  + KLV   M++AV+LAVPL V+   G++WY+AK
Sbjct  836  IVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

143) polA in NC_004567


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  829 bits (3138),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 512/885 (58%), Positives = 691/885 (79%), Gaps = 14/885 (1%)

Query  3    KKLLLIDGNSVAFRAFFALHSQLERFVNPDGLHTNAIYGFNTMLDHMIKAVEPTDMLVAF  62
            +KLLLIDG+SVAFRAFFAL +Q++RF N  GLHTNAIYGF+ MLDHM+K V PT++LVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  63   DAGKTTFRTAMYDNYKGGRAKTPSEFSEQMPYIKQLLDAYGIKHYELKDYEADDIIGTLA  122
            DAGKTTFRT MY +YK+GRAKTP EF EQ +YI+++L A GI  YEL +YEADDIIGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  123  AQADQTG--YTTTVVTGDRDLTQLTTEHTTVAVTVKGVSEVEHYTPAHVEEKLGITPAQI  180
              A++T   +  T+V+GD+DL QLT E+T V ++ KGV+E E++TPA + EK+G+TP Q+
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  181  IDMKGLTGDTSDNYPGVTKVGEKTALKLLKQYGTMEGIYENIDAMKQSKMKEHLIEDREQ  240
            ID+K+L GD SDN PGVTK+GEKT+LKLL ++G++EGIYE+ID+ K SKMKE+LI+DR+Q
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRDQ  244

Query  241  AAQAKVLATIKRDAPIDVQLADLSYDGPDLDQLAAFYQKMDFQSFLKKLHLQ-SDEPATP  299
            A  +K LATI+  +PI + L D+ Y+GPD+  L+ FY+ MDF  + K L  Q ++EP + 
Sbjct  245  AFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEPVAV  304

Query  300  IDYTVLTKANLTELQQFTDHVDFYLEMPTPNYHTSAFAGFAIGADDHWYISRDVELLMQP  359
            I Y  +T+ + ++L  F+ +  FY+E    NYH  A+ GFA G +++ Y S D+ LL   
Sbjct  305  ISYQEVTNVS-ADL--FSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLATD  361

Query  360  TVADLLSSTTITKDVFDMKRTTVGLNRLGIQLGKVDFDLLLVSYLLDTNDNSNDLGSLAE  419
            +  +++     T   +D KR+ V L++LGI+L    +D  L +YLL T ++ N+L+++A 
Sbjct  362  SFKQVFQKPIAT---YDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NELSTIAR  417

Query  420  QHGYTDLPSDETVYGKGVKRAIPEDDDVFFSHLARKLAAIASLKPQLLKELAANEQDQLY  479
                  L  D+TVYGKG KRA+P D DV++ HLARK+  +   K+Q+L  L+A+EQ +LY
Sbjct  418  IFTDISLEEDDTVYGKGAKRAVP-DKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLY  476

Query  480  DDIEKPMANVLAQMEIAGITVDSSRLKAMGSQFTERLSEIEQTIYQEAGEEFNINSPKQL  539
            ++IE P+ANVLA+MEI GI V+ + L+ M+ Q    +  + Q IY+ AG+EFNINSPKQL
Sbjct  477  QNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQL  536

Query  540  GHILFEEMKLP--VIKKTKTGYSTAVDVLEKLAPEAPIVANILQYRQISKIQSTYVVGLL  597
            G ILFE M+LP  + KKTKTGYSTAVDVLE+LAP APIVA+IL+YRQI+K+QSTYV+GL 
Sbjct  537  GSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQ  596

Query  598  DAIHSADQKVHTRYLQTLTQTGRLSSVDPNLQNIPVRLEEGRKIRQAFVPSHEGWQIFSS  657
            D I  AD K+HTRY+Q LTQTGRLSSVDPNLQNIP+RLE+GR IR+AF PSHE+  ++SS
Sbjct  597  DYIL-ADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSS  655

Query  658  DYSQIELRVLAHITDDENMQAAFKAGDDIHAATAMRIFHLNSAEEVTPNIRRQAKAVNFG  717
            DYSQIELRVLAHI++DE++ AAF+ G DIH++TAMR+F ++ A +VT+N RR+AKAVNFG
Sbjct  656  DYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFG  715

Query  718  IVYGISDYGLSQNIGITRKQARSFIDAYFKEYPGVKKYMDEIVQTAKKQGYVETISHRRR  777
            IVYGISD+GLS+N+GITRKQ++S+ID+YF  YPG+K YM+++V+ AK +GYVET+  RRR
Sbjct  716  IVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRR  775

Query  778  YLPDINSKSFNQRSFAERTAMNTPIQGSaadiikiamikmqdkLQAAGLKATMLLQVHDE  837
             LPDINS++FN RSFAERTA+N+PIQGSAADI+KIAMI+++  LQA+G++A MLLQVHDE
Sbjct  776  ELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDE  835

Query  838  LIFEAPKEEIPVLEKLVPSVMDSAVQLAVPLKVESHYGDTWYDAK  882
            +++E P++E+  + KLV   M++AV+LAVPL V+   G++WY+AK
Sbjct  836  IVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

144) polA in NC_014554


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  828 bits (3135),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 513/885 (58%), Positives = 690/885 (78%), Gaps = 14/885 (1%)

Query  3    KKLLLIDGNSVAFRAFFALHSQLERFVNPDGLHTNAIYGFNTMLDHMIKAVEPTDMLVAF  62
            +KLLLIDG+SVAFRAFFAL +Q++RF N  GLHTNAIYGF+ MLDHM+K V PT++LVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  63   DAGKTTFRTAMYDNYKGGRAKTPSEFSEQMPYIKQLLDAYGIKHYELKDYEADDIIGTLA  122
            DAGKTTFRT MY +YK+GRAKTP EF EQ +YI+++L A GI  YEL +YEADDIIGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  123  GQADQTG--YTTTVVTGDRDLTQLTTEHTTVAVTVKGVSEVERYTPAHVEEKLGITPAQI  180
              A++T   +  T+V+GD+DL QLT E+T V ++ KGV+E E +TPA + EK+G+TP Q+
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  181  IDMKGLTGDTSDNYPGVTKVGEKTALKLLKQYGTMEGIYENIDAMKQSKMKEHLIEDREQ  240
            ID+K+L GD SDN PGVTK+GEKT+LKLL ++G++EGIYE+ID+ K SKMKE+LI+DR+Q
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRDQ  244

Query  241  AAQAKVLATIKRDAPIDVQLADLSYDGPDLDQLAAFYQKMDFQSFLKKLHLQ-SDEPATP  299
            A  +K LATI+  +PI + L D+ Y+GPD+  L+ FY+ MDF  + K L  Q ++EP + 
Sbjct  245  AFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEPVAV  304

Query  300  IDYTVLTKANLTELQQFTDHVDFYLEMPTPNYHTSAFAGFAIGADDHWYISRDVELLMQP  359
            I Y  +T+ + ++L  F+ +  FY+E    NYH  A+ GFA G +++ Y S D+ LL   
Sbjct  305  ISYQEVTNVS-ADL--FSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLATD  361

Query  360  TVADLLSSTTITKDVFDMKRTTVGLNRLGIQLGKVDFDLLLVSYLLDTNDNSNDLGSLAE  419
            +  +++     T   +D KR+ V L++LGI+L    +D  L +YLL T ++ N+L+++A 
Sbjct  362  SFKQVFQKPIAT---YDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NELSTIAR  417

Query  420  QHGYTDLPSDETVYGKGVKRAIPEDDDVFFSHLARKLAAIASLKPQLLKELAANEQDQLY  479
                  L  D+TVYGKG KRA+P D DV++ HLARK+  +   K+Q+L  L+A+EQ +LY
Sbjct  418  IFTDISLEEDDTVYGKGAKRAVP-DKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLY  476

Query  480  DDIEKPMANVLAQMEIAGITVDSSRLKAMGSQFTERLSEIEQTIYQEAGEEFNINSPKQL  539
            ++IE P+ANVLA+MEI GI V+ + L+ M+ Q    +  + Q IY+ AG+EFNINSPKQL
Sbjct  477  QNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQL  536

Query  540  GHILFEEMKLP--VIKKTKTGYSTAVDVLEKLAPEAPIVANILQYRQISKIQSTYVIGLL  597
            G ILFE M+LP  + KKTKTGYSTAVDVLE+LAP APIVA+IL+YRQI+K+QSTYVIGL 
Sbjct  537  GSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQ  596

Query  598  DAIHSADQKVHTRYLQTLTQTGRLSSVDPNLQNIPVRLEEGRKIRQAFVPSHEGWQIFSS  657
            D I  AD K+HTRY+Q LTQTGRLSSVDPNLQNIP+RLE+GR IR+AF PSHE+  ++SS
Sbjct  597  DYIL-ADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSS  655

Query  658  DYSQIELRVLAHITDDENMQAAFKAGDDIHAATAMRIFHLNSAEEVTPNIRRQAKAVNFG  717
            DYSQIELRVLAHI++DE++ AAF+ G DIH++TAMR+F ++ A +VT+N RR+AKAVNFG
Sbjct  656  DYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFG  715

Query  718  IVYGISDYGLSQNIGITRKQARSFIDAYFKEYPGVKKYMDEIVQTAKKQGYVETISHRRR  777
            IVYGISD+GLS+N+GITRKQ++S+ID+YF  YPG+K YM+++V+ AK +GYVET+  RRR
Sbjct  716  IVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRR  775

Query  778  YLPDINSKSFNQRSFAERTAMNTPIQGSaadiikiamikmqdkLQAAGLKATMLLQVHDE  837
             LPDINS++FN RSFAERTA+N+PIQGSAADI+KIAMI+++  LQA+G++A MLLQVHDE
Sbjct  776  ELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDE  835

Query  838  LIFEAPKEEIPVLEKLVPSVMDSAVQLAVPLKVESHYGDTWYDAK  882
            +++E P++E+  + KLV   M++AV+LAVPL V+   G++WY+AK
Sbjct  836  IVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

145) polA in NC_020229


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  828 bits (3133),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 513/885 (58%), Positives = 690/885 (78%), Gaps = 14/885 (1%)

Query  8    KKLLLIDGNSVAFRAFFALHSQLERFVNPDGLHTNAIYGFNTMLDHMIKAVEPTDMLVAF  67
            +KLLLIDG+SVAFRAFFAL +Q++RF N  GLHTNAIYGF+ MLDHM+K V PT++LVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  68   DAGKTTFRTAMYDNYKGGRAKTPSEFSEQMPYIKQLLDAYGIKHYELKDYEADDIIGTLA  127
            DAGKTTFRT MY +YK+GRAKTP EF EQ +YI+++L A GI  YEL +YEADDIIGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  128  GQADQTG--YTTTVVTGDRDLTQLTTEHTTVAVTVKGVSEVERYTPAHVEEKLGITPAQI  185
              A++T   +  T+V+GD+DL QLT E+T V ++ KGV+E E +TPA + EK+G+TP Q+
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  186  IDMKGLTGDTSDNYPGVTKVGEKTALKLLKQYGTMEGIYENIDAMKQSKMKEHLIEDREQ  245
            ID+K+L GD SDN PGVTK+GEKT+LKLL ++G++EGIYE+ID+ K SKMKE+LI+DR+Q
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRDQ  244

Query  246  AAQAKVLATIKRDAPIDVQLADLSYDGPDLDQLAAFYQKMDFQSFLKKLHLQ-SDEPATP  304
            A  +K LATI+  +PI + L D+ Y+GPD+  L+ FY+ MDF  + K L  Q ++EP + 
Sbjct  245  AFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEPVAV  304

Query  305  IDYTVLTKSNLTELQQFTDHVDFYLEMPTPNYHTSAFAGFAIGADDHWYISRDVELLMQP  364
            I Y  +T+ + ++L  F+ +  FY+E    NYH  A+ GFA G +++ Y S D+ LL   
Sbjct  305  ISYQEVTNVS-ADL--FSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLATD  361

Query  365  TVADLLSSTTITKDVFDMKRTTVGLNRLGIQLGKVDFDLLLVSYLLDTNDNSNDLGSLAE  424
            +  +++     T   +D KR+ V L++LGI+L    +D  L +YLL T ++ N+L+++A 
Sbjct  362  SFKQVFQKPIAT---YDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NELSTIAR  417

Query  425  QHGYTDLPSDETVYGKGVKRAIPEDDDVFFSHLARKLAAIASLKPQLLKELAANEQDQLY  484
                  L  D+TVYGKG KRA+P D DV++ HLARK+  +   K+Q+L  L+A+EQ +LY
Sbjct  418  IFTDISLEEDDTVYGKGAKRAVP-DKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLY  476

Query  485  DDIEKPMANVLAQMEIAGITVDSSRLKAMGSQFTERLSEIEQTIYQEAGEEFNINSPKQL  544
            ++IE P+ANVLA+MEI GI V+ + L+ M+ Q    +  + Q IY+ AG+EFNINSPKQL
Sbjct  477  QNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQL  536

Query  545  GHILFEEMKLP--VIKKTKTGYSTAVDVLEKLAPEAPIVANILQYRQISKIQSTYVIGLL  602
            G ILFE M+LP  + KKTKTGYSTAVDVLE+LAP APIVA+IL+YRQI+K+QSTYVIGL 
Sbjct  537  GSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQ  596

Query  603  DAIHSADQKVHTRYLQTLTQTGRLSSVDPNLQNIPVRLEEGRKIRQAFVPSHEGWQIFSS  662
            D I  AD K+HTRY+Q LTQTGRLSSVDPNLQNIP+RLE+GR IR+AF PSHE+  ++SS
Sbjct  597  DYIL-ADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSS  655

Query  663  DYSQIELRVLAHITDDENMQAAFKAGDDIHAATAMRIFHLNSAEEVTPNIRRQAKAVNFG  722
            DYSQIELRVLAHI++DE++ AAF+ G DIH++TAMR+F ++ A +VT+N RR+AKAVNFG
Sbjct  656  DYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFG  715

Query  723  IVYGISDYGLSQNIGITRKQARSFIDAYFKEYPGVKKYMDEIVQTAKKQGYVETISHRRR  782
            IVYGISD+GLS+N+GITRKQ++S+ID+YF  YPG+K YM+++V+ AK +GYVET+  RRR
Sbjct  716  IVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRR  775

Query  783  YLPDINSKSFNQRSFAERTAMNTPIQGSaadiikiamikmqdkLQAAGLKATMLLQVHDE  842
             LPDINS++FN RSFAERTA+N+PIQGSAADI+KIAMI+++  LQA+G++A MLLQVHDE
Sbjct  776  ELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDE  835

Query  843  LIFEAPKEEIPVLEKLVPSVMDSAVQLAVPLKVESHYGDTWYDAK  887
            +++E P++E+  + KLV   M++AV+LAVPL V+   G++WY+AK
Sbjct  836  IVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

146) Lp16_1139 in NC_021514


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  826 bits (3129),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 512/885 (58%), Positives = 690/885 (78%), Gaps = 14/885 (1%)

Query  3    KKLLLIDGNSVAFRAFFALHSQLERFVNPDGLHTNAIYGFNTMLDHMIKAVEPTDMLVAF  62
            +KLLLIDG+SVAFRAFFAL +Q++RF N  GLHTNAIYGF+ MLDHM+K V PT++LVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  63   DAGKTTFRTAMYDNYKGGRAKTPSEFSEQMPYIKQLLDAYGIKHYELKDYEADDIIGTLA  122
            DAGKTTFRT MY +YK+GRAKTP EF EQ +YI+++L A GI  YEL +YEADDIIGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  123  GQADQTG--YTTTVVTGDRDLTQLTTEHTTVAVTVKGVSEVEHYTPAHVEEKLGITPAQI  180
              A++T   +  T+V+GD+DL QLT E+T V ++ KGV+E E++TPA + EK+G+TP Q+
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  181  IDMKGLTGDTSDNYPGVTKVGEKTALKLLKQYGTMEGIYENIDAMKQSKMKEHLIEDREQ  240
            ID+K+L GD SDN PGVTK+GEKT+LKLL ++G++EGIYE+ID+ K SKMKE+LI+DR+Q
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRDQ  244

Query  241  AAQAKVLATIKRDAPIDVQLADLSYDGPDLDQLAAFYQKMDFQSFLKKLHLQ-SDEPATP  299
            A  +K LATI+  +PI + L D+ Y+GPD+  L+ FY+ MDF  + K L  Q ++EP + 
Sbjct  245  AFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEPVAV  304

Query  300  IDYTVLTKANLTELQQFTDHVDFYLEMPTPNYHTSAFAGFAIGADDHWYISRDVELLMQP  359
            I Y  +T+ + ++L  F+ +  FY+E    NYH  A+ GFA G +++ Y S D+ LL   
Sbjct  305  ISYQEVTNVS-ADL--FSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLATD  361

Query  360  TVADLLSSTTITKDVFDMKRTTVGLNRLGIQLGKVDFDLLLVSYLLDTNDNSNDLGSLAE  419
            +  +++     T   +D KR+ V L++LGI+L    +D  L +YLL T ++ N+L+++A 
Sbjct  362  SFKQVFQKPIAT---YDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NELSTIAR  417

Query  420  QHGYTDLPSDETVYGKGVKRAIPEDDDVYFSHLARKLAAIASLKPQLLKELAANEQDQLY  479
                  L  D+TVYGKG KRA+P D DV + HLARK+  +   K+Q+L  L+A+EQ +LY
Sbjct  418  IFTDISLEEDDTVYGKGAKRAVP-DKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLY  476

Query  480  DDIEKPMANVLAQMEIAGITVDSSRLKAMGSQFTERLSEIEQTIYQEAGEEFNINSPKQL  539
            ++IE P+ANVLA+MEI GI V+ + L+ M+ Q    +  + Q IY+ AG+EFNINSPKQL
Sbjct  477  QNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQL  536

Query  540  GHILFEEMKLP--VIKKTKTGYSTAVDVLEKLAPEAPIVANILQYRQISKIQSTYVVGLL  597
            G ILFE M+LP  + KKTKTGYSTAVDVLE+LAP APIVA+IL+YRQI+K+QSTYV+GL 
Sbjct  537  GSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQ  596

Query  598  DAIHSADQKVHTRYLQTLTQTGRLSSVDPNLQNIPVRLEEGRKIRQAFVPSHEGWQIFSS  657
            D I  AD K+HTRY+Q LTQTGRLSSVDPNLQNIP+RLE+GR IR+AF PSHE+  ++SS
Sbjct  597  DYIL-ADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSS  655

Query  658  DYSQIELRVLAHITDDENMQAAFKAGDDIHAATAMRIFHLNSAEEVTPNIRRQAKAVNFG  717
            DYSQIELRVLAHI++DE++ AAF+ G DIH++TAMR+F ++ A +VT+N RR+AKAVNFG
Sbjct  656  DYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFG  715

Query  718  IVYGISDYGLSQNIGITRKQARSFIDAYFKEYPGVKKYMDEIVQTAKKQGYVETISHRRR  777
            IVYGISD+GLS+N+GITRKQ++S+ID+YF  YPG+K YM+++V+ AK +GYVET+  RRR
Sbjct  716  IVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRR  775

Query  778  YLPDINSKSFNQRSFAERTAMNTPIQGSaadiikiamikmqdkLQAAGLKATMLLQVHDE  837
             LPDINS++FN RSFAERTA+N+PIQGSAADI+KIAMI+++  LQA+G++A MLLQVHDE
Sbjct  776  ELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDE  835

Query  838  LIFEAPKEEIPVLEKLVPSVMDSAVQLAVPLKVESHYGDTWYDAK  882
            +++E P++E+  + KLV   M++AV+LAVPL V+   G++WY+AK
Sbjct  836  IVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

147) polA in NC_021224


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  825 bits (3125),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 511/885 (58%), Positives = 690/885 (78%), Gaps = 14/885 (1%)

Query  8    KKLLLIDGNSVAFRAFFALHSQLERFVNPDGLHTNAIYGFNTMLDHMIKAVEPTDMLVAF  67
            +KLLLIDG+SVAFRAFFAL +Q++RF N  GLHTNAIYGF+ MLDHM+K V PT++LVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  68   DAGKTTFRTAMYDNYKGGRAKTPSEFSEQMPYIKQLLDAYGIKHYELKDYEADDIIGTLA  127
            DAGKTTFRT MY +YK+GRAKTP EF EQ +YI+++L A GI  YEL +YEADDIIGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  128  GQADQTG--YTTTVVTGDRDLTQLTTEHTTVAVTVKGVSEVEHYTPAHVEEKLGITPAQI  185
              A++T   +  T+V+GD+DL QLT E+T V ++ KGV+E E++TPA + EK+G+TP Q+
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  186  IDMKGLTGDTSDNYPGVTKVGEKTALKLLKQYGTMEGIYENIDAMKQSKMKEHLIEDREQ  245
            ID+K+L GD SDN PGVTK+GEKT+LKLL ++G++EGIYE+ID+ K SKMKE+LI+DR+Q
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRDQ  244

Query  246  AAQAKVLATIKRDAPIDVQLADLSYDGPDLDQLAAFYQKMDFQSFLKKLHLQ-SDEPATP  304
            A  +K LATI+  +PI + L D+ Y+GPD+  L+ FY+ MDF  + K L  Q ++EP + 
Sbjct  245  AFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEPVAV  304

Query  305  IDYTVLTKANLTELQQFTDHVDFYLEMPTPNYHTSAFAGFAIGADDHWYISRDVELLMQP  364
            I Y  +T+ + ++L  F+ +  FY+E    NYH  A+ GFA G +++ Y S D+ LL   
Sbjct  305  ISYQEVTNVS-ADL--FSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLATD  361

Query  365  TVADLLSSTTITKDVFDMKRTTVGLNRLGIQLGKVDFDLLLVSYLLDTNDNSNDLGSLAE  424
            +  +++     T   +D KR+ V L++LGI+L    +D  L +YLL T ++ N+L+++A 
Sbjct  362  SFKQVFQKPIAT---YDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NELSTIAR  417

Query  425  QHGYTDLPSDETVYGKGVKRAIPEDDDVYFSHLARNLAAIASLKPQLLKELAANEQDQLY  484
                  L  D+TVYGKG KRA+P D DV + HLAR++  +   K+Q+L  L+A+EQ +LY
Sbjct  418  IFTDISLEEDDTVYGKGAKRAVP-DKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLY  476

Query  485  DDIEKPMANVLAQMEIAGITVDSSRLKAMGSQFTERLSEIEQTIYQEAGEEFNINSPKQL  544
            ++IE P+ANVLA+MEI GI V+ + L+ M+ Q    +  + Q IY+ AG+EFNINSPKQL
Sbjct  477  QNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQL  536

Query  545  GHILFEEMKLP--VIKKTKTGYSTAVDVLEKLAPEAPIVANILQYRQISKIQSTYVVGLL  602
            G ILFE M+LP  + KKTKTGYSTAVDVLE+LAP APIVA+IL+YRQI+K+QSTYV+GL 
Sbjct  537  GSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQ  596

Query  603  DAIHSADQKVHTRYLQTLTQTGRLSSVDPNLQNIPVRLEEGRKIRQAFVPSHEGWQIFSS  662
            D I  AD K+HTRY+Q LTQTGRLSSVDPNLQNIP+RLE+GR IR+AF PSHE+  ++SS
Sbjct  597  DYIL-ADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSS  655

Query  663  DYSQIELRVLAHITDDENMQAAFKAGDDIHAATAMRIFHLNSAEEVTPNIRRQAKAVNFG  722
            DYSQIELRVLAHI++DE++ AAF+ G DIH++TAMR+F ++ A +VT+N RR+AKAVNFG
Sbjct  656  DYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFG  715

Query  723  IVYGISDYGLSQNIGITRKQARSFIDAYFKEYPGVKKYMDEIVQTAKKQGYVETISHRRR  782
            IVYGISD+GLS+N+GITRKQ++S+ID+YF  YPG+K YM+++V+ AK +GYVET+  RRR
Sbjct  716  IVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRR  775

Query  783  YLPDINSKSFNQRSFAERTAMNTPIQGSaadiikiamikmqdkLQAAGLKATMLLQVHDE  842
             LPDINS++FN RSFAERTA+N+PIQGSAADI+KIAMI+++  LQA+G++A MLLQVHDE
Sbjct  776  ELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDE  835

Query  843  LIFEAPKEEIPVLEKLVPSVMDSAVQLAVPLKVESHYGDTWYDAK  887
            +++E P++E+  + KLV   M++AV+LAVPL V+   G++WY+AK
Sbjct  836  IVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

148) polA in NC_007576


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  821 bits (3109),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 487/890 (55%), Positives = 678/890 (77%), Gaps = 15/890 (1%)

Query  1    MGSQKSLLLIDGNSVAFRAFYAMHQVLDSFTNQDGLHTNAIYAFKNMLDIILKRFEPTHV  60
            M +++ LLLIDG+SVAFRAF+A+ + +D F N+ GLHTNAIY+F  MLD ++KR  PTHV
Sbjct  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60

Query  61   LVAFDAGKTTFRTAQFADYKGGRSKTPPELTEQFPYIKELLHAYGIQTAELANYEADDII  120
            LVAFDAGKTTFRT  +ADYK+GR+KTP E+ EQF+YI+E+L A GI   EL +YEADDII
Sbjct  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120

Query  121  GTLASQAEQDG--FVVNIVTGDRDLTQLTTDKTTVNITVKGVNDTEAYTPEHVQEKLGLA  178
            GTL   AE+    F V IV+GD+DL QLT ++T V+I+ KGV + E +TP  + EK+GL+
Sbjct  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180

Query  179  PSQIVDLKGLMGDTSDNYPGVTKVGEKTALKLLTEFGSIEGVYENVDAMKKSKMKEHLIE  238
            P+Q++DLK+LMGD SDN PGVTK+GEKT+LKLL EFGS+EG+YE++D+ K SKMKE+LI+
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  239  DRDQAFMSKKLATILRDAPIETTLADITYEGPNIDTLIAFYQEMNFQNFLKQLNV-TPEA  297
            DRDQAF+SK LATI   +PI   L DI Y+GP++ +L  FY+EM+F ++ K L    P+ 
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQE  300

Query  298  VEPAENYQYTVLTLDNLETVQAIKTPVAFGVEMLTDNYHTADLIGFYIGAPDHWYVSDDV  357
              +  +YQ       +L + + I     F  E L DNYH   +IGF  G  ++ Y S D+
Sbjct  301  PVAVISYQEVTNVSADLFSAEDI-----FYFETLRDNYHREAIIGFAWGHGEQIYASTDL  355

Query  358  ALLAEPVLKDWLEDASHPKAVFGVKRTQVAANRLGVHLAGVDFDLLLASYLLNTTNNSND  417
            +LLA   +K+ ++    P A ++ KR++V  ++LG++L +  +D  LA+YLL+T ++ N+
Sbjct  356  SLLATDSFKQVFQ---KPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NE  411

Query  418  LGTVANLHEYQNVQTDEAVYGKGAKRAVPTEPALLYQHLVQKAAAIYHLQPQLEEQLKEH  477
            L+T+A +    +++ D++VYGKGAKRAVP    LL +HL +K   + + ++Q+ ++L  H
Sbjct  412  LSTIARIFTDISLEEDDTVYGKGAKRAVPDKDVLL-EHLARKVKVLLDSKSQMLDKLTAH  470

Query  478  QQFDLFTDMELPLALVLAQMEITGIRVDASRLQQMGSEFSQTLKILEEKVYAEAGETFNI  537
            +Q+DL+ ++ELPLA VLA+MEI GI+V+ + LQ+M+ +    +  L + +Y  AG+ FNI
Sbjct  471  EQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNI  530

Query  538  NSPKQLGVILFEKMGLP--VVKKTKTGYSTAVDVLEQLRKDAPIVQTILDYRQIAKIQST  595
            NSPKQLG ILFEKM LP  + KKTKTGYSTAVDVLE+L   APIV  ILDYRQI+K+QST
Sbjct  531  NSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQST  590

Query  596  YVEGLLKSIHQDNKVHTRYLQTLTQTGRLSSVDPNLQNIPVRLAEGRKIRQAFVPSHPDW  655
            YV GL   I  D K+HTRY+Q LTQTGRLSSVDPNLQNIP+RL +GR IR+AF PSH D 
Sbjct  591  YVIGLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDA  650

Query  656  QMFASDYSQIELRVLAHISGDANMQEAFKEDRDIHANTAMKIFGLNSADEVTPDMRRQAK  715
             +++SDYSQIELRVLAHISGD ++  AF+E+ DIH++TAM++FG++ A +VT++ RR+AK
Sbjct  651  VLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAK  710

Query  716  ATNFGIVYGISDYGLSQNIGISRQEAKRFIDAYFEQYPGVQQFMVDIVKKAREEGYVETL  775
            A NFGIVYGISD+GLS+N+GI+R+++K +ID+YFE+YPG++ +M ++V+ A++ GYVETL
Sbjct  711  AVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETL  770

Query  776  FHRRRYLPDIHAKNFNLRSFAERTAMNTPIQGSAADIIKVAMILMQQELKKANLQARMLL  835
            F RRR LPDI+++NFN+RSFAERTA+N+PIQGSAADI+K+AMI +++ L+ + ++A+MLL
Sbjct  771  FKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLL  830

Query  836  QVHDELIFEAPTEEIPILQKLVPSVMDSAVKLAVPLKVESGFGPTWYDIK  885
            QVHDE+++E P +E+  ++KLV   M++AV LAVPL V+ + G +WY+ K
Sbjct  831  QVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

149) polA in NC_015391


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  806 bits (3050),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 493/891 (56%), Positives = 692/891 (78%), Gaps = 16/891 (1%)

Query  2    MSEKKKLVLIDGNSVAYRAFFALHSQLERMKNKNGLHTNALYGFHNMIDSVLTKEKPTHV  61
            M +K+KL+LIDG+SVA+RAFFAL +Q++R KN +GLHTNA+YGFH M+D ++ + +PTHV
Sbjct  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60

Query  62   LVAFDAGNTTFRHSFFDEYKAGRSKTPREFSEQMPYLRELLDGFGIRHYELENFEADDII  121
            LVAFDAG+TTFR   + +YKAGR+KTP EF EQ +Y+RE+L ++GI  YELE++EADDII
Sbjct  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120

Query  122  GTLATKVDPT--IYDVVVISGDRDLTQLAKENVRVDITVKGVSELKEYTTESIYEEMGIS  179
            GTL    + T   +DV ++SGD+DL QL+ EN  V+I+ KGV+E+ E+T   + E MG++
Sbjct  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180

Query  180  PLQIIDMKGLAGDASDNIPGVTKIGEKTALKLLKEYGSVEGIYENIDLLKKSKMKENLIN  239
            P Q+ID+K+L GD SDNIPGVTKIGEKT+LKLL E+GS+EGIYE+ID +K SKMKENLIN
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  240  EKETALLSKRLATIDTDSPIKISVEELSFNGPNMEKLISFYKEMDFNSHLSKLDTAEYDA  299
            +++ A+LSK LATI+T SPI I+++++ +NGP++  L  FY EMDF  +L K  +++   
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDF-VQLKKGLASQMPQ  299

Query  300  EQNSQKEAISYTIVTEITENMFNDNMALYVEMLGDNYHTSPVFCIGWGDDQQIYVAEPEV  359
            E  +    ISY  VT+++ ++F+ +  +Y E L DNYH  +++ ++WG+++QIY +    
Sbjct  300  EPVA---VISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLS  356

Query  360  VFASDDFKN-WAKDKEAQKQVFDAKRTYVALKRQNVDIASIDFDILLASYLLNTKDNSKD  418
            ++A+D FK+   K   +    +D KR+ V L +  +++ +  +D  LA+YLL+T +++ +
Sbjct  357  LLATDSFKQVFQKPIAT----YDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDN-E  411

Query  419  LSEVATEHEYYEVSSDESVYGKGAKIAIPEEKTIIYDHIARKIKAIRILSKQLGENLEKN  478
            LS +A       +  D++VYGKGAK A+P+ K ++ +H+ARK+K +     Q+ ++L  +
Sbjct  412  LSTIARIFTDISLEEDDTVYGKGAKRAVPD-KDVLLEHLARKVKVLLDSKSQMLDKLTAH  470

Query  479  EQTKLFNEMELPLSMVLAEMELTGVKVNDKRLMEMKEEFAIRLTDIEQRVYELAGEKFNL  538
            EQ  L++++ELPL+ VLA ME+ G+KVN   L +M E+  + +  + Q +Y++AG+ FN+
Sbjct  471  EQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNI  530

Query  539  NSPKQLGVILFEKMGYPV--IKKTKTGYSTAVDVLEQLREQAPIVEHILDYRQIAKIQST  596
            NSPKQLG ILFEKM  P+   KKTKTGYSTAVDVLE+L   APIV  ILDYRQI+K+QST
Sbjct  531  NSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQST  590

Query  597  YIEGLLKVIDKKTGKIHTRYMQTIAQTGRLSSVDPNLQNIPIRLEEGRKIRQAFVPSHEG  656
            Y+ GL   I    GKIHTRY+Q ++QTGRLSSVDPNLQNIPIRLE+GR IR+AF PSHE+
Sbjct  591  YVIGLQDYI-LADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHED  649

Query  657  WEIFASDYSQIELRVLGHVSDDKLLKEAFIEGQDIHSSTAMQVFGIGSPEEVSSEMRRRA  716
              +++SDYSQIELRVL+H+S+D  L  AF EG DIH+STAM+VFGI+ + +V+++ RR A
Sbjct  650  AVLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNA  709

Query  717  KAVNFGIVYGISDYGLSQNLGISRKEAQHFIDTYFEKYPGVKTYMEDIVREAKDKGFVET  776
            KAVNFGIVYGISD+GLS+NLGI+RK+++ +IDTYFE+YPG+K+YME++VREAKDKG+VET
Sbjct  710  KAVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVET  769

Query  777  LFQRRRYLPEINSRNFNLRSFAERTAINTPIQGSaadiikiamikmdQKLKESTMKATML  836
            LF+RRR LP+INSRNFN+RSFAERTAIN+PIQGSAADI+KIAMI++D+ L+ +  +A ML
Sbjct  770  LFKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKML  829

Query  837  LQVHDELIFEAPKEEIEQLRALVVEVMEGAVELSVPLKVDSNSGKSWYEAK  887
            LQVHDE+++E P++E+  ++ LV + ME+AV+L+VPL VD ++G+SWYEAK
Sbjct  830  LQVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

150) polA in NC_017491


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  800 bits (3027),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 483/887 (55%), Positives = 679/887 (77%), Gaps = 13/887 (1%)

Query  1    MTSQTKLLLIDGNSIAFRAFFALYNQLDRFTNQDGLHTNAIYAFNNMLEIVLKSVKPDAA  60
            M ++ KLLLIDG+S+AFRAFFALYNQ+DRF N+ GLHTNAIY+F+ ML+ ++K V+P   
Sbjct  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60

Query  61   LVAFDAGKTTFRTAKYADYKSGRAKTPSELLEQLPYIKELLDDMGIQHYELKDYEADDII  120
            LVAFDAGKTTFRT  YADYK+GRAKTP E+ EQ++YI+E+L  +GI  YEL +YEADDII
Sbjct  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120

Query  121  GTMAKRAD--DAGWQTTIVTGDRdltqlttdqttvqvtvKGVNELEAYTPEHVKEKLGIT  178
            GT+ K A+  +   + TIV+GD+DL QLT ++T V+++ KGV E+E +TP  + EK+G+T
Sbjct  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180

Query  179  PTQIIDLKGLMGDTSDNYPGVTKVGEKTALKLLKQYGSIENLYANIDAMKTSKMKENLIN  238
            P Q+IDLK+LMGD SDN PGVTK+GEKT+LKLL ++GS+E +Y +ID+ KTSKMKENLIN
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  239  DKDKAYLSKQLATIDRDAPVTIDLADVKYNGPDLAKLRDFYTKMNMNSLLKKIGGDVAK-  297
            D+D+A+LSK LATI+  +P+TI+L D+ YNGPD+A L +FY  M+   L K +++++++ 
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQE  300

Query  298  PSQPVHYSVLDDQSILALTKTTEPLTFEIEMLADNYHTAEQVGFFIGTKEETYVSTDVSL  357
            P   + Y  + + S   L  + + + FE   L DNYH    +GF  G  E+ Y STD+SL
Sbjct  301  PVAVISYQEVTNVSA-DLFSAEDIFYFET--LRDNYHREAIIGFAWGHGEQIYASTDLSL  357

Query  358  LTIPEVAKWLGDSNRDLTVFDGKRNIVAAHRLGLHLPDIAFDVLLASYLINPDENSNDLG  417
            L+     + +   ++ ++ +D KR+ V   +LG++L   ++D  LA+YL++  E+ N+L+
Sbjct  358  LATDSFKQVF---QKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NELS  413

Query  418  KIAEDHDYHDLPRDEDVYGKGAKRQVPEDKLLFEQFARKSQALFALRPDLTEDLAKQEQT  477
             IA       L  D+ VYGKGAKR VP+  +L+E++ARK + L+  ++++ + L+ +EQ 
Sbjct  414  TIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQL  473

Query  478  DLFTDMEMPLARVLAEMEIQGITLNAQTLKDMGTEFSQSIKVLEEKIYGEAGVKFNLNSP  537
            DL+ ++E+PLA VLA MEI+GI +N  TL+DM+ +    I  L + IY+ AG  FN+NSP
Sbjct  474  DLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSP  533

Query  538  KQLGEVLFEKLNLP--VIKKTKTGYSTSVDVLNELKSASPIVQDILDYRGWAKLNSTYVV  595
            KQLG +LFEK++LP  + KKTKTGYST+VDVL+ L + +PIV  ILDYR  +KL+STYV+
Sbjct  534  KQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVI  593

Query  596  GLLKAQMPDHKIHTRYLQTLTQTGRLSSVDPNMQNIPAR-DEGKIIRKAFVPSHPDWQIF  654
            GL    ++D KIHTRY+Q LTQTGRLSSVDPN+QNIP R ++G++IRKAF PSH D  ++
Sbjct  594  GLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLL  653

Query  655  SSDYSQIELRVLSHISGDENMQQAFKHGVDIHANTAMKIFGLDSPDEVTPDMRRQAKATN  714
            SSDYSQIELRVL+HISGDE++  AF++G DIH++TAM++FG+D + +VT++ RR+AKA N
Sbjct  654  SSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVN  713

Query  715  FGIVYGISDYGLAQNIGISRKQAKAFIDGYFEQYPKVHDYMENMVKKAREDGYVETLFHR  774
            FGIVYGISD+GL++N+GI+RKQ+K++ID YFE+YP +  YMEN+V+ A++ GYVETLF R
Sbjct  714  FGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKR  773

Query  775  RRYLPQIHSRNFNLRKFAERTAMNTPIQGSAADIIKVAMIRMQKALDEAHLQAKMLLQVH  834
            RR LP+I+SRNFN+R FAERTA+N+PIQGSAADI+K+AMI ++KAL+ + ++AKMLLQVH
Sbjct  774  RRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVH  833

Query  835  DELIFEAPTAEMAQLGQLVPKIMDSAVSLAVPLKVESHYGPTWFDAK  881
            DE+++E P  E++ + +LV   M++AV LAVPL V+   G +W++AK
Sbjct  834  DEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

151) LOCK900_1700 in NC_021723


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  800 bits (3029),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 483/887 (55%), Positives = 679/887 (77%), Gaps = 13/887 (1%)

Query  1    MTSQTKLLLIDGNSIAFRAFFALYNQLDRFTNQDGLHTNAIYAFNNMLEIVLKSVKPDAA  60
            M ++ KLLLIDG+S+AFRAFFALYNQ+DRF N+ GLHTNAIY+F+ ML+ ++K V+P   
Sbjct  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60

Query  61   LVAFDAGKTTFRTAKYADYKSGRAKTPSELLEQLPYIKELLDDMGIQHYELKDYEADDII  120
            LVAFDAGKTTFRT  YADYK+GRAKTP E+ EQ++YI+E+L  +GI  YEL +YEADDII
Sbjct  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120

Query  121  GTMAKRAD--DAGWQTTIVTGDRdltqlttdqttvqvtvKGVNELEAYTPEHVKEKLGIT  178
            GT+ K A+  +   + TIV+GD+DL QLT ++T V+++ KGV E+E +TP  + EK+G+T
Sbjct  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180

Query  179  PTQIIDLKGLMGDTSDNYPGVTKVGEKTALKLLKQYGSIENLYANIDAMKTSKMKENLIN  238
            P Q+IDLK+LMGD SDN PGVTK+GEKT+LKLL ++GS+E +Y +ID+ KTSKMKENLIN
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  239  DKDKAYLSKQLATIDRDAPVTIDLADVKYNGPDLAKLRDFYTKMNMNSLLKKIGGDVAK-  297
            D+D+A+LSK LATI+  +P+TI+L D+ YNGPD+A L +FY  M+   L K +++++++ 
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQE  300

Query  298  PSQPVHYSVLDDQSILALTKTTEPLTFEIEMLADNYHTAEQVGFFIGTKEETYVSTDVSL  357
            P   + Y  + + S   L  + + + FE   L DNYH    +GF  G  E+ Y STD+SL
Sbjct  301  PVAVISYQEVTNVSA-DLFSAEDIFYFET--LRDNYHREAIIGFAWGHGEQIYASTDLSL  357

Query  358  LTISEVAKWLGDSNRDLTVFDGKRNIVAAHRLGLHLPDIAFDVLLASYLINPDENSNDLG  417
            L+     + +   ++ ++ +D KR+ V   +LG++L   ++D  LA+YL++  E+ N+L+
Sbjct  358  LATDSFKQVF---QKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NELS  413

Query  418  KIAEDHDYHDLPRDEDVYGKGAKRQVPEDKLLFEQFARKSQALFALRPDLTEDLAKQEQT  477
             IA       L  D+ VYGKGAKR VP+  +L+E++ARK + L+  ++++ + L+ +EQ 
Sbjct  414  TIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQL  473

Query  478  DLFTDMEMPLARVLAEMEIQGITLNAQTLKDMGTEFSQSIKVLEEKIYGEAGVKFNLNSP  537
            DL+ ++E+PLA VLA MEI+GI +N  TL+DM+ +    I  L + IY+ AG  FN+NSP
Sbjct  474  DLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSP  533

Query  538  KQLGEVLFEKLNLP--VIKKTKTGYSTSVDVLNELKSASPIVQDILDYRGWAKLNSTYVV  595
            KQLG +LFEK++LP  + KKTKTGYST+VDVL+ L + +PIV  ILDYR  +KL+STYV+
Sbjct  534  KQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVI  593

Query  596  GLLKAQMPDHKIHTRYLQTLTQTGRLSSVDPNMQNIPAR-DEGKIIRKAFVPSHPDWQIF  654
            GL    ++D KIHTRY+Q LTQTGRLSSVDPN+QNIP R ++G++IRKAF PSH D  ++
Sbjct  594  GLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLL  653

Query  655  SSDYSQIELRVLSHISGDENMQQAFKHGVDIHANTAMKIFGLDSPDEVTPDMRRQAKATN  714
            SSDYSQIELRVL+HISGDE++  AF++G DIH++TAM++FG+D + +VT++ RR+AKA N
Sbjct  654  SSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVN  713

Query  715  FGIVYGISDYGLAQNIGISRKQAKAFIDGYFEQYPKVHDYMENMVKKAREDGYVETLFHR  774
            FGIVYGISD+GL++N+GI+RKQ+K++ID YFE+YP +  YMEN+V+ A++ GYVETLF R
Sbjct  714  FGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKR  773

Query  775  RRYLPQIHSRNFNLRKFAERTAMNTPIQGSAADIIKVAMIRMQKALDEAHLQAKMLLQVH  834
            RR LP+I+SRNFN+R FAERTA+N+PIQGSAADI+K+AMI ++KAL+ + ++AKMLLQVH
Sbjct  774  RRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVH  833

Query  835  DELIFEAPTAEMAQLGQLVPKIMDSAVSLAVPLKVESHYGPTWFDAK  881
            DE+++E P  E++ + +LV   M++AV LAVPL V+   G +W++AK
Sbjct  834  DEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

152) LOCK908_1794 in NC_021725


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  800 bits (3027),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 483/887 (55%), Positives = 679/887 (77%), Gaps = 13/887 (1%)

Query  1    MTSQTKLLLIDGNSIAFRAFFALYNQLDRFTNQDGLHTNAIYAFNNMLEIVLKSVKPDAA  60
            M ++ KLLLIDG+S+AFRAFFALYNQ+DRF N+ GLHTNAIY+F+ ML+ ++K V+P   
Sbjct  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60

Query  61   LVAFDAGKTTFRTAKYADYKSGRAKTPSELLEQLPYIKELLDDMGIQHYELKDYEADDII  120
            LVAFDAGKTTFRT  YADYK+GRAKTP E+ EQ++YI+E+L  +GI  YEL +YEADDII
Sbjct  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120

Query  121  GTMAKRAD--DAGWQTTIVTGDRdltqlttdqttvqvtvKGVNELEAYTPEHVKEKLGIT  178
            GT+ K A+  +   + TIV+GD+DL QLT ++T V+++ KGV E+E +TP  + EK+G+T
Sbjct  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180

Query  179  PTQIIDLKGLMGDTSDNYPGVTKVGEKTALKLLKQYGSIENLYANIDSMKTSKMKENLIN  238
            P Q+IDLK+LMGD SDN PGVTK+GEKT+LKLL ++GS+E +Y +ID+ KTSKMKENLIN
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  239  DKDKAYLSKQLATIDRDAPVTIDLADVKYNGPDLAKLRDFYTKMNMNSLLKKIGGDVAK-  297
            D+D+A+LSK LATI+  +P+TI+L D+ YNGPD+A L +FY  M+   L K +++++++ 
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQE  300

Query  298  PSQPVHYSVLDDQSILALTKTTEPLTFEIEMLADNYHTAEQVGFFIGTKEETYVSTDVSL  357
            P   + Y  + + S   L  + + + FE   L DNYH    +GF  G  E+ Y STD+SL
Sbjct  301  PVAVISYQEVTNVSA-DLFSAEDIFYFET--LRDNYHREAIIGFAWGHGEQIYASTDLSL  357

Query  358  LTIPEVAKWLGDSNRDLTVFDGKRNIVAAHRLGLHLPDIAFDVLLASYLINPDENSNDLG  417
            L+     + +   ++ ++ +D KR+ V   +LG++L   ++D  LA+YL++  E+ N+L+
Sbjct  358  LATDSFKQVF---QKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NELS  413

Query  418  KIAEDHDYHDLPRDEDVYGKGAKRQVPEDKLLFEQFARKSQALFALRPDLTEDLAKQEQT  477
             IA       L  D+ VYGKGAKR VP+  +L+E++ARK + L+  ++++ + L+ +EQ 
Sbjct  414  TIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQL  473

Query  478  DLFTDMEMPLARVLAEMEIQGITLNAQTLKDMGTEFSQSIKVLEEKIYGEAGVKFNLNSP  537
            DL+ ++E+PLA VLA MEI+GI +N  TL+DM+ +    I  L + IY+ AG  FN+NSP
Sbjct  474  DLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSP  533

Query  538  KQLGEVLFEKLNLP--VIKKTKTGYSTSVDVLNELKSASPIVQDILDYRGWAKLNSTYVV  595
            KQLG +LFEK++LP  + KKTKTGYST+VDVL+ L + +PIV  ILDYR  +KL+STYV+
Sbjct  534  KQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVI  593

Query  596  GLLKAQMPDHKIHTRYLQTLTQTGRLSSVDPNMQNIPAR-DEGKIIRKAFVPSHPDWQIF  654
            GL    ++D KIHTRY+Q LTQTGRLSSVDPN+QNIP R ++G++IRKAF PSH D  ++
Sbjct  594  GLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLL  653

Query  655  SSDYSQIELRVLSHISGDENMQQAFKHGVDIHANTAMKIFGLDSPDEVTPDMRRQAKATN  714
            SSDYSQIELRVL+HISGDE++  AF++G DIH++TAM++FG+D + +VT++ RR+AKA N
Sbjct  654  SSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVN  713

Query  715  FGIVYGISDYGLAQNIGISRKQAKAFIDGYFEQYPKVHDYMENMVKKAREDGYVETLFHR  774
            FGIVYGISD+GL++N+GI+RKQ+K++ID YFE+YP +  YMEN+V+ A++ GYVETLF R
Sbjct  714  FGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKR  773

Query  775  RRYLPQIHSRNFNLRKFAERTAMNTPIQGSAADIIKVAMIRMQKALDEAHLQAKMLLQVH  834
            RR LP+I+SRNFN+R FAERTA+N+PIQGSAADI+K+AMI ++KAL+ + ++AKMLLQVH
Sbjct  774  RRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVH  833

Query  835  DELIFEAPTAEMAQLGQLVPKIMDSAVSLAVPLKVESHYGPTWFDAK  881
            DE+++E P  E++ + +LV   M++AV LAVPL V+   G +W++AK
Sbjct  834  DEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

153) polA in NC_014106


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  800 bits (3027),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 473/890 (54%), Positives = 676/890 (76%), Gaps = 20/890 (2%)

Query  4    KKLLLIDGNSVAFRAFYALYRQLESFKSPDGLHTNAIYAFKNMLDVLLKDVDPTHVLVAF  63
            +KLLLIDG+SVAFRAF+ALY Q++ FK+  GLHTNAIY+F  MLD ++K V PTHVLVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  64   DAGKVTFRTKMYGDYKGGRAKTPEELLEQMPYIQEMLHDLGIKTYELKDYEADDIIGTFA  123
            DAGK TFRT MY+DYK+GRAKTP+E+ EQ +YI+EML  LGI  YEL +YEADDIIGT+ 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  124  TKGE--ENGFTTTIVTGDRDLTQLASDKTTVEVTKSGVSQLEAYTPEHMKEVNGVTPTEF  181
              +E  E  F  TIV+GD+DL QL+ ++T VE++K GV+++E +TP  + E  G+TP +F
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  182  IDMKALMGDSSDNYPGVEGIGPKTASNLIQKYHTVENLYDHIDDLKASKRKERLIRDKHN  241
            ID+KALMGD SDN PGV  IG KT+ +L++ + ++E +Y+HID++K+SK KE LI D+++
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRDQ  244

Query  242  AILGKKLATIDRHSPVTIDIDDVKRQPIDYEKLRQFYEKMNFRKFLAELNASGQGQDATE  301
            A+L+K LATI+  SP+TI++DD+  +  D   L QFY+ M+F ++   L AS   Q++  
Sbjct  245  AFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGL-ASQMPQEPVA  303

Query  302  VEKVEYTVLDDQNVKEIKAN--ADDQIEFYLAMLGANYHLAPFVGFALKINDQIYVSRDV  359
            V  + Y     Q+V ++ A+  + ++I FY+  L  NYH  +++GFA    +QIY S D+
Sbjct  304  V--ISY-----QEVTNVSADLFSAEDI-FYFETLRDNYHREAIIGFAWGHGEQIYASTDL  355

Query  360  ELLQETNLRHLLEDEQIKKNVFDLKRTMVGLHRLGIHVHGQDYDMLLASYLINNENNSND  419
             LL   +++++++        +D+KR+ V L +LGI++ +  YD  LA+YL++  ++ N+
Sbjct  356  SLLATDSFKQVFQKP---IATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NE  411

Query  420  LGEIAHLYGDYSVKTDIEIYGKGKSEHVPDDDEELFNHLASKVNAIENLKQPLLEKLKEH  479
            L+ IA+++ D S+  D  +YGKG    VPD D  L++HLA KV+ + + K  +L+KL  H
Sbjct  412  LSTIARIFTDISLEEDDTVYGKGAKRAVPDKDV-LLEHLARKVKVLLDSKSQMLDKLTAH  470

Query  480  EQDDLFDTIEIPTARVLARMEINGMKVEASTLLELQNEFAVRLKELEDKIYQQAGERFNL  539
            EQ DL++ IE+P A VLA+MEI+G+KV+ +TL ++ ++  V +  L + IY+ AG+ FN+
Sbjct  471  EQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNI  530

Query  540  NSPKQLGHILFEKLNLP--VIKKTKTGYSTSVEVLDQLKTQSPIVSEILDYRQIAKIQST  597
            NSPKQLG ILFEK++LP  + KKTKTGYST+V+VL++L   +PIV+ ILDYRQI+K+QST
Sbjct  531  NSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQST  590

Query  598  YVKGLLDVIQPDGRVHTRYLQTLTATGRLSSVDPNLQNIPTRTEEGKQIRKAFVPTEPDG  657
            YV GL D I +DG++HTRY+Q LT TGRLSSVDPNLQNIP R E+G+ IRKAF P++ D+
Sbjct  591  YVIGLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDA  650

Query  658  YIFSCDYSQVELRVLAHVSGDQNMQEAFKTGYDIHSHTAMRIFHLDSPDEVTPLMRRHAK  717
             ++S DYSQ+ELRVLAH+SGD+++  AF+ G DIH+ TAMR+F +D + +VT+  RR+AK
Sbjct  651  VLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAK  710

Query  718  AVNFGIVYGISDYGLSKNLGISRKRAQEFIDNYFEQYPQIREYMDKAVQTAREKGYAETI  777
            AVNFGIVYGISD+GLS+NLGI+RK+++ +ID YFE+YP I+ YM++ V+ A++KGY ET+
Sbjct  711  AVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETL  770

Query  778  MHRRRYLPDIHAKKFTVRSFAERTAINSPIQGSAADIIKIAMINMQKKLDELHLKTKMVV  837
              RRR LPDI++++F VRSFAERTAINSPIQGSAADI+KIAMIN++K L+   +++KM++
Sbjct  771  FKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLL  830

Query  838  QVHDELIFDVPKDELETIKKIVPEVMQSAVKLDVPLIADSGWGHNWYDAK  887
            QVHDE++++VP+DEL +IKK+V + M++AV L VPL  D + G++WY+AK
Sbjct  831  QVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

154) LRHM_1697 in NC_017482


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  799 bits (3024),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 482/887 (55%), Positives = 678/887 (77%), Gaps = 13/887 (1%)

Query  1    MTSQTKLLLIDGNSIAFRAFFALYNQLDRFTNQDGLHTNAIYAFNNMLEIVLKSVKPDAA  60
            M ++ KLLLIDG+S+AFRAFFALYNQ+DRF N+ GLHTNAIY+F+ ML+ ++K V+P   
Sbjct  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60

Query  61   LVAFDAGKTTFRTAKYADYKSGRAKTPSELLEQLPYIKELLDDMGIQHYELKDYEADDII  120
            LVAFDAGKTTFRT  YADYK+GRAKTP E+ EQ++YI+E+L  +GI  YEL +YEADDII
Sbjct  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120

Query  121  GTMAKRAD--DAGWQTTIVTGDRdltqlttdqttvqvtvKGVNELEAYTPEHVKEKLGIT  178
            GT+ K A+  +   + TIV+GD+DL QLT ++T V+++ KGV E+E +TP  + EK+G+T
Sbjct  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180

Query  179  PTQIIDLKGLMGDTSDNYPGVTKVGEKTALKLLKQYGSIENLYANIDAMKTSKMKESLIN  238
            P Q+IDLK+LMGD SDN PGVTK+GEKT+LKLL ++GS+E +Y +ID+ KTSKMKE+LIN
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  239  DKDKAYLSKQLATIDRDAPVTIDLADVKYNGPDLAKLRDFYTKMNMNSLLKKIGGDVAK-  297
            D+D+A+LSK LATI+  +P+TI+L D+ YNGPD+A L +FY  M+   L K +++++++ 
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQE  300

Query  298  PSQPVHYSVLDDQSILALTKTTEPLTFEIEMLADNYHTAEQVGFFIGTKEETYVSTDVSL  357
            P   + Y  + + S   L  + + + FE   L DNYH    +GF  G  E+ Y STD+SL
Sbjct  301  PVAVISYQEVTNVSA-DLFSAEDIFYFET--LRDNYHREAIIGFAWGHGEQIYASTDLSL  357

Query  358  LTIPEVAKWLGDSNRDLTVFDGKRNIVAAHRLGLKLPDIAFDVLLASYLINPDENSNDLG  417
            L+     + +   ++ ++ +D KR+ V   +LG+ L   ++D  LA+YL++  E+ N+L+
Sbjct  358  LATDSFKQVF---QKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NELS  413

Query  418  KIAEDHDYHDLPRDEDVYGKGAKRQVPEDKLLFEQFARKSQALFALRPDLTEDLAKQEQT  477
             IA       L  D+ VYGKGAKR VP+  +L+E++ARK + L+  ++++ + L+ +EQ 
Sbjct  414  TIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQL  473

Query  478  DLFTDMEMPLARVLAEMEIQGITLNAQTLKDMGTEFSQSIKVLEEKIYGEAGVKFNLNSP  537
            DL+ ++E+PLA VLA MEI+GI +N  TL+DM+ +    I  L + IY+ AG  FN+NSP
Sbjct  474  DLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSP  533

Query  538  KQLGEVLFEKLNLP--VIKKTKTGYSTSVDVLNELKSASPIVQDILDYRGWAKLNSTYVV  595
            KQLG +LFEK++LP  + KKTKTGYST+VDVL+ L + +PIV  ILDYR  +KL+STYV+
Sbjct  534  KQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVI  593

Query  596  GLLKAQMPDHKIHTRYLQTLTQTGRLSSVDPNMQNIPAR-DEGKIIRKAFVPSHPDWQIF  654
            GL    ++D KIHTRY+Q LTQTGRLSSVDPN+QNIP R ++G++IRKAF PSH D  ++
Sbjct  594  GLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLL  653

Query  655  SSDYSQIELRVLSHISGDENMQQAFKHGVDIHANTAMKIFGLDSPDEVTPDMRRQAKATN  714
            SSDYSQIELRVL+HISGDE++  AF++G DIH++TAM++FG+D + +VT++ RR+AKA N
Sbjct  654  SSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVN  713

Query  715  FGIVYGISDYGLAQNIGISRKQAKAFIDGYFEQYPKVHDYMENMVKKAREDGYVETLFHR  774
            FGIVYGISD+GL++N+GI+RKQ+K++ID YFE+YP +  YMEN+V+ A++ GYVETLF R
Sbjct  714  FGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKR  773

Query  775  RRYLPQIHSRNFNLRKFAERTAMNTPIQGSAADIIKVAMIRMQKALDEAHLQAKMLLQVH  834
            RR LP+I+SRNFN+R FAERTA+N+PIQGSAADI+K+AMI ++KAL+ + ++AKMLLQVH
Sbjct  774  RRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVH  833

Query  835  DELIFEAPTAEMAQLGQLVPKIMDSAVSLAVPLKVESHYGPTWFDAK  881
            DE+++E P  E++ + +LV   M++AV LAVPL V+   G +W++AK
Sbjct  834  DEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

155) polA in NC_013198


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  799 bits (3024),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 482/887 (55%), Positives = 678/887 (77%), Gaps = 13/887 (1%)

Query  1    MTSQTKLLLIDGNSIAFRAFFALYNQLDRFTNQDGLHTNAIYAFNNMLEIVLKSVKPDAA  60
            M ++ KLLLIDG+S+AFRAFFALYNQ+DRF N+ GLHTNAIY+F+ ML+ ++K V+P   
Sbjct  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60

Query  61   LVAFDAGKTTFRTAKYADYKSGRAKTPSELLEQLPYIKELLDDMGIQHYELKDYEADDII  120
            LVAFDAGKTTFRT  YADYK+GRAKTP E+ EQ++YI+E+L  +GI  YEL +YEADDII
Sbjct  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120

Query  121  GTMAKRAD--DAGWQTTIVTGDRdltqlttdqttvqvtvKGVNELEAYTPEHVKEKLGIT  178
            GT+ K A+  +   + TIV+GD+DL QLT ++T V+++ KGV E+E +TP  + EK+G+T
Sbjct  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180

Query  179  PTQIIDLKGLMGDTSDNYPGVTKVGEKTALKLLKQYGSIENLYANIDAMKTSKMKESLIN  238
            P Q+IDLK+LMGD SDN PGVTK+GEKT+LKLL ++GS+E +Y +ID+ KTSKMKE+LIN
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  239  DKDKAYLSKQLATIDRDAPVTIDLADVKYNGPDLAKLRDFYTKMNMNSLLKKIGGDVAK-  297
            D+D+A+LSK LATI+  +P+TI+L D+ YNGPD+A L +FY  M+   L K +++++++ 
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQE  300

Query  298  PSQPVHYSVLDDQSILALTKTTEPLTFEIEMLADNYHTAEQVGFFIGTKEETYVSTDVSL  357
            P   + Y  + + S   L  + + + FE   L DNYH    +GF  G  E+ Y STD+SL
Sbjct  301  PVAVISYQEVTNVSA-DLFSAEDIFYFET--LRDNYHREAIIGFAWGHGEQIYASTDLSL  357

Query  358  LTIPEVAKWLGDSNRDLTVFDGKRNIVAAHRLGLKLPDIAFDVLLASYLINPDENSNDLG  417
            L+     + +   ++ ++ +D KR+ V   +LG+ L   ++D  LA+YL++  E+ N+L+
Sbjct  358  LATDSFKQVF---QKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NELS  413

Query  418  KIAEDHDYHDLPRDEDVYGKGAKRQVPEDKLLFEQFARKSQALFALRPDLTEDLAKQEQT  477
             IA       L  D+ VYGKGAKR VP+  +L+E++ARK + L+  ++++ + L+ +EQ 
Sbjct  414  TIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQL  473

Query  478  DLFTDMEMPLARVLAEMEIQGITLNAQTLKDMGTEFSQSIKVLEEKIYGEAGVKFNLNSP  537
            DL+ ++E+PLA VLA MEI+GI +N  TL+DM+ +    I  L + IY+ AG  FN+NSP
Sbjct  474  DLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSP  533

Query  538  KQLGEVLFEKLNLP--VIKKTKTGYSTSVDVLNELKSASPIVQDILDYRGWAKLNSTYVV  595
            KQLG +LFEK++LP  + KKTKTGYST+VDVL+ L + +PIV  ILDYR  +KL+STYV+
Sbjct  534  KQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVI  593

Query  596  GLLKAQMPDHKIHTRYLQTLTQTGRLSSVDPNMQNIPAR-DEGKIIRKAFVPSHPDWQIF  654
            GL    ++D KIHTRY+Q LTQTGRLSSVDPN+QNIP R ++G++IRKAF PSH D  ++
Sbjct  594  GLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLL  653

Query  655  SSDYSQIELRVLSHISGDENMQQAFKHGVDIHANTAMKIFGLDSPDEVTPDMRRQAKATN  714
            SSDYSQIELRVL+HISGDE++  AF++G DIH++TAM++FG+D + +VT++ RR+AKA N
Sbjct  654  SSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVN  713

Query  715  FGIVYGISDYGLAQNIGISRKQAKAFIDGYFEQYPKVHDYMENMVKKAREDGYVETLFHR  774
            FGIVYGISD+GL++N+GI+RKQ+K++ID YFE+YP +  YMEN+V+ A++ GYVETLF R
Sbjct  714  FGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKR  773

Query  775  RRYLPQIHSRNFNLRKFAERTAMNTPIQGSAADIIKVAMIRMQKALDEAHLQAKMLLQVH  834
            RR LP+I+SRNFN+R FAERTA+N+PIQGSAADI+K+AMI ++KAL+ + ++AKMLLQVH
Sbjct  774  RRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVH  833

Query  835  DELIFEAPTAEMAQLGQLVPKIMDSAVSLAVPLKVESHYGPTWFDAK  881
            DE+++E P  E++ + +LV   M++AV LAVPL V+   G +W++AK
Sbjct  834  DEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

156) LCBD_1905 in NC_017474


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  797 bits (3016),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 478/887 (54%), Positives = 677/887 (77%), Gaps = 13/887 (1%)

Query  1    MASKTKLLLVDGNSVAFRAFFALYNQLDRFTNQDGLHTNAIYAFNNMLEIVLKAVQPDAA  60
            M +K KLLL+DG+SVAFRAFFALYNQ+DRF N+ GLHTNAIY+F+ ML+ ++K V+P   
Sbjct  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60

Query  61   LVAFDAGKTTFRTAKYADYKSGRAKTPSELLEQLPYIKELLDDMGIAHYELKDYEADDII  120
            LVAFDAGKTTFRT  YADYK+GRAKTP E+ EQ++YI+E+L  +GIA YEL +YEADDII
Sbjct  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120

Query  121  GTMDKRAD--EAGWETTIVTGdrdltqlttdrttvqvtvKGVNELEAYTPAHVKEKLGIT  178
            GT+DK A+  E   + TIV+GD+DL QLT + T V+++ KGV E+E +TPA + EK+G+T
Sbjct  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180

Query  179  PAQIIDLKGLMGDTSDNYPGVTKVGEKTALKLLNQYGSMENLYANVDDMKKSKLKENLIN  238
            P Q+IDLK+LMGD SDN PGVTK+GEKT+LKLL+++GS+E +Y ++D+ K SK+KENLIN
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  239  DKDSAFLSKQLATIDRDAPLTVDLADVTYAGPDLDKLRDFYTKMNMNSLLKKIGGSVAK-  297
            D+D AFLSK LATI+  +P+T++L D+ Y GPD+  L +FY  M+   L K +++ +++ 
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQE  300

Query  298  PVQAVHFSVLDEQSILALTKLTEPLTFEIEMLEDNYHVAEQIGFFIGTKEETYVSTDITL  357
            PV  + +   +E + ++   ++    F +E L DNYH    IGF  G  E+ Y STD++L
Sbjct  301  PVAVISY---QEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSL  357

Query  358  LTLPAVKRWLEDAKRDLTVFDGKRNIVAANRLGVKLPDIAFDVLLASYLINPDENSNDLG  417
            L+  + K+ ++   + ++ +D KR+ V  ++LG+ L   ++D  LA+YL++  E+ N+L+
Sbjct  358  LATDSFKQVFQ---KPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NELS  413

Query  418  KIAEDHDYHDLPRDEDIYGKGAKRQVPEDDKLFGQFARKSNALFALRPDLTGDLEKQAQT  477
             IA       L  D+ +YGKGAKR VP+ D L+ ++ARK + L+  ++++ + L  + Q 
Sbjct  414  TIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQL  473

Query  478  DLFTDMEMPLSRVLAEMEIQGITLNAKTLKAMGTEFSQSIKILEEKIYAEAGVKFNLNSP  537
            DL+ ++E+PL+ VLA MEI+GI +N  TL+ M+ +    I  L + IY  AG  FN+NSP
Sbjct  474  DLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSP  533

Query  538  KQLGEILFEKLNLP--VIKKTKTGYSTSVDVLNELKSASPIVQDILDYRGWAKLNSTYVV  595
            KQLG ILFEK++LP  + KKTKTGYST+VDVL+ L + +PIV  ILDYR  +KL+STYV+
Sbjct  534  KQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVI  593

Query  596  GLLKAQLPDHKIHTRYLQTLTQTGRLSSVDPNMQNIPAR-DEGKIIRKAFVPSHEGWQIF  654
            GL    L+D KIHTRY+Q LTQTGRLSSVDPN+QNIP R ++G++IRKAF PSHE+  ++
Sbjct  594  GLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLL  653

Query  655  SSDYSQIELRVLSHISGDENMQEAFKHGVDIHANTAMKIFGLSSPDQVTPDMRRQAKATN  714
            SSDYSQIELRVL+HISGDE++  AF++G DIH++TAM++FG+  + +VT++ RR+AKA N
Sbjct  654  SSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVN  713

Query  715  FGIVYGISDYGLSQNIGISRKQAKAFIDGYFDQYPKVHDYMDAMVKKAREDGYVETLFHR  774
            FGIVYGISD+GLS+N+GI+RKQ+K++ID YF++YP +  YM+ +V+ A++ GYVETLF R
Sbjct  714  FGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKR  773

Query  775  RRYLPQIHSRNFNLRKFAERTAMNTPIQGSAADIIKVAMIRMQKALDEAGLQAKMLLQVH  834
            RR LP+I+SRNFN+R FAERTA+N+PIQGSAADI+K+AMI ++KAL+ +G++AKMLLQVH
Sbjct  774  RRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVH  833

Query  835  DELIFEAPEEEIAQLSELVPKVMDSAVHLDVPLKVESHYGPTWFDAK  881
            DE+++E P++E++ +  LV   M++AV+L VPL V+   G +W++AK
Sbjct  834  DEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

157) LC2W_1884 in NC_017473


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  797 bits (3016),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 478/887 (54%), Positives = 677/887 (77%), Gaps = 13/887 (1%)

Query  1    MASKTKLLLVDGNSVAFRAFFALYNQLDRFTNQDGLHTNAIYAFNNMLEIVLKAVQPDAA  60
            M +K KLLL+DG+SVAFRAFFALYNQ+DRF N+ GLHTNAIY+F+ ML+ ++K V+P   
Sbjct  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60

Query  61   LVAFDAGKTTFRTAKYADYKSGRAKTPSELLEQLPYIKELLDDMGIAHYELKDYEADDII  120
            LVAFDAGKTTFRT  YADYK+GRAKTP E+ EQ++YI+E+L  +GIA YEL +YEADDII
Sbjct  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120

Query  121  GTMDKRAD--EAGWETTIVTGdrdltqlttdrttvqvtvKGVNELEAYTPAHVKEKLGIT  178
            GT+DK A+  E   + TIV+GD+DL QLT + T V+++ KGV E+E +TPA + EK+G+T
Sbjct  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180

Query  179  PAQIIDLKGLMGDTSDNYPGVTKVGEKTALKLLNQYGSMENLYANVDDMKKSKLKENLIN  238
            P Q+IDLK+LMGD SDN PGVTK+GEKT+LKLL+++GS+E +Y ++D+ K SK+KENLIN
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  239  DKDSAFLSKQLATIDRDAPLTVDLADVTYAGPDLDKLRDFYTKMNMNSLLKKIGGSVAK-  297
            D+D AFLSK LATI+  +P+T++L D+ Y GPD+  L +FY  M+   L K +++ +++ 
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQE  300

Query  298  PVQAVHFSVLDEQSILALTKLTEPLTFEIEMLEDNYHVAEQIGFFIGTKEETYVSTDITL  357
            PV  + +   +E + ++   ++    F +E L DNYH    IGF  G  E+ Y STD++L
Sbjct  301  PVAVISY---QEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSL  357

Query  358  LTLPAVKRWLEDAKRDLTVFDGKRNIVAANRLGVKLPDIAFDVLLASYLINPDENSNDLG  417
            L+  + K+ ++   + ++ +D KR+ V  ++LG+ L   ++D  LA+YL++  E+ N+L+
Sbjct  358  LATDSFKQVFQ---KPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NELS  413

Query  418  KIAEDHDYHDLPRDEDIYGKGAKRQVPEDDKLFGQFARKSNALFALRPDLTGDLEKQAQT  477
             IA       L  D+ +YGKGAKR VP+ D L+ ++ARK + L+  ++++ + L  + Q 
Sbjct  414  TIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQL  473

Query  478  DLFTDMEMPLSRVLAEMEIQGITLNAKTLKAMGTEFSQSIKILEEKIYAEAGVKFNLNSP  537
            DL+ ++E+PL+ VLA MEI+GI +N  TL+ M+ +    I  L + IY  AG  FN+NSP
Sbjct  474  DLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSP  533

Query  538  KQLGEILFEKLNLP--VIKKTKTGYSTSVDVLNELKSASPIVQDILDYRGWAKLNSTYVV  595
            KQLG ILFEK++LP  + KKTKTGYST+VDVL+ L + +PIV  ILDYR  +KL+STYV+
Sbjct  534  KQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVI  593

Query  596  GLLKAQLPDHKIHTRYLQTLTQTGRLSSVDPNMQNIPAR-DEGKIIRKAFVPSHEGWQIF  654
            GL    L+D KIHTRY+Q LTQTGRLSSVDPN+QNIP R ++G++IRKAF PSHE+  ++
Sbjct  594  GLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLL  653

Query  655  SSDYSQIELRVLSHISGDENMQEAFKHGVDIHANTAMKIFGLSSPDQVTPDMRRQAKATN  714
            SSDYSQIELRVL+HISGDE++  AF++G DIH++TAM++FG+  + +VT++ RR+AKA N
Sbjct  654  SSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVN  713

Query  715  FGIVYGISDYGLSQNIGISRKQAKAFIDGYFDQYPKVHDYMDAMVKKAREDGYVETLFHR  774
            FGIVYGISD+GLS+N+GI+RKQ+K++ID YF++YP +  YM+ +V+ A++ GYVETLF R
Sbjct  714  FGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKR  773

Query  775  RRYLPQIHSRNFNLRKFAERTAMNTPIQGSAADIIKVAMIRMQKALDEAGLQAKMLLQVH  834
            RR LP+I+SRNFN+R FAERTA+N+PIQGSAADI+K+AMI ++KAL+ +G++AKMLLQVH
Sbjct  774  RRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVH  833

Query  835  DELIFEAPEEEIAQLSELVPKVMDSAVHLDVPLKVESHYGPTWFDAK  881
            DE+++E P++E++ +  LV   M++AV+L VPL V+   G +W++AK
Sbjct  834  DEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

158) polA in NC_018641


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  797 bits (3017),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 478/887 (54%), Positives = 677/887 (77%), Gaps = 13/887 (1%)

Query  22   MASKTKLLLVDGNSVAFRAFFALYNQLDRFTNQDGLHTNAIYAFNNMLEIVLKAVQPDAA  81
            M +K KLLL+DG+SVAFRAFFALYNQ+DRF N+ GLHTNAIY+F+ ML+ ++K V+P   
Sbjct  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60

Query  82   LVAFDAGKTTFRTAKYADYKSGRAKTPSELLEQLPYIKELLDDMGIAHYELKDYEADDII  141
            LVAFDAGKTTFRT  YADYK+GRAKTP E+ EQ++YI+E+L  +GIA YEL +YEADDII
Sbjct  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120

Query  142  GTMDKRAD--EAGWETTIVTGdrdltqlttdrttvqvtvKGVNELEAYTPAHVKEKLGIT  199
            GT+DK A+  E   + TIV+GD+DL QLT + T V+++ KGV E+E +TPA + EK+G+T
Sbjct  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180

Query  200  PAQIIDLKGLMGDTSDNYPGVTKVGEKTALKLLNQYGSMENLYANVDDMKKSKLKENLIN  259
            P Q+IDLK+LMGD SDN PGVTK+GEKT+LKLL+++GS+E +Y ++D+ K SK+KENLIN
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  260  DKDSAFLSKQLATIDRDAPLTVDLADVTYAGPDLDKLRDFYTKMNMNSLLKKIGGSVAK-  318
            D+D AFLSK LATI+  +P+T++L D+ Y GPD+  L +FY  M+   L K +++ +++ 
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQE  300

Query  319  PVQAVHFSVLDEQSILALTKLTEPLTFEIEMLEDNYHVAEQIGFFIGTKEETYVSTDITL  378
            PV  + +   +E + ++   ++    F +E L DNYH    IGF  G  E+ Y STD++L
Sbjct  301  PVAVISY---QEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSL  357

Query  379  LTLPAVKRWLEDAKRDLTVFDGKRNIVAANRLGVKLPDIAFDVLLASYLINPDENSNDLG  438
            L+  + K+ ++   + ++ +D KR+ V  ++LG+ L   ++D  LA+YL++  E+ N+L+
Sbjct  358  LATDSFKQVFQ---KPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NELS  413

Query  439  KIAEDHDYHDLPRDEDIYGKGAKRQVPEDDKLFGQFARKSNALFALRPDLTGDLEKQAQT  498
             IA       L  D+ +YGKGAKR VP+ D L+ ++ARK + L+  ++++ + L  + Q 
Sbjct  414  TIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQL  473

Query  499  DLFTDMEMPLSRVLAEMEIQGITLNAKTLKAMGTEFSQSIKILEEKIYAEAGVKFNLNSP  558
            DL+ ++E+PL+ VLA MEI+GI +N  TL+ M+ +    I  L + IY  AG  FN+NSP
Sbjct  474  DLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSP  533

Query  559  KQLGEILFEKLNLP--VIKKTKTGYSTSVDVLNELKSASPIVQDILDYRGWAKLNSTYVV  616
            KQLG ILFEK++LP  + KKTKTGYST+VDVL+ L + +PIV  ILDYR  +KL+STYV+
Sbjct  534  KQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVI  593

Query  617  GLLKAQLPDHKIHTRYLQTLTQTGRLSSVDPNMQNIPAR-DEGKIIRKAFVPSHEGWQIF  675
            GL    L+D KIHTRY+Q LTQTGRLSSVDPN+QNIP R ++G++IRKAF PSHE+  ++
Sbjct  594  GLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLL  653

Query  676  SSDYSQIELRVLSHISGDENMQEAFKHGVDIHANTAMKIFGLSSPDQVTPDMRRQAKATN  735
            SSDYSQIELRVL+HISGDE++  AF++G DIH++TAM++FG+  + +VT++ RR+AKA N
Sbjct  654  SSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVN  713

Query  736  FGIVYGISDYGLSQNIGISRKQAKAFIDGYFDQYPKVHDYMDAMVKKAREDGYVETLFHR  795
            FGIVYGISD+GLS+N+GI+RKQ+K++ID YF++YP +  YM+ +V+ A++ GYVETLF R
Sbjct  714  FGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKR  773

Query  796  RRYLPQIHSRNFNLRKFAERTAMNTPIQGSAADIIKVAMIRMQKALDEAGLQAKMLLQVH  855
            RR LP+I+SRNFN+R FAERTA+N+PIQGSAADI+K+AMI ++KAL+ +G++AKMLLQVH
Sbjct  774  RRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVH  833

Query  856  DELIFEAPEEEIAQLSELVPKVMDSAVHLDVPLKVESHYGPTWFDAK  902
            DE+++E P++E++ +  LV   M++AV+L VPL V+   G +W++AK
Sbjct  834  DEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

159) polA in NC_010999


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  796 bits (3012),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 477/887 (54%), Positives = 676/887 (77%), Gaps = 13/887 (1%)

Query  1    MASKTKLLLVDGNSVAFRAFFALYNQLDRFTNQDGLHTNAIYAFNNMLEIVLKAVQPDAA  60
            M +K KLLL+DG+SVAFRAFFALYNQ+DRF N+ GLHTNAIY+F+ ML+ ++K V+P   
Sbjct  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60

Query  61   LVAFDAGKTTFRTAKYADYKSGRAKTPSELLEQLPYIKELLDDMGIAHYELKDYEADDII  120
            LVAFDAGKTTFRT  YADYK+GRAKTP E+ EQ++YI+E+L  +GIA YEL +YEADDII
Sbjct  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120

Query  121  GTMAKRAD--EAGWETTIVTGdrdltqlttdrttvqvtvKGVNELEAYTPAHVKEKLGIT  178
            GT+ K A+  E   + TIV+GD+DL QLT + T V+++ KGV E+E +TPA + EK+G+T
Sbjct  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180

Query  179  PAQIIDLKGLMGDTSDNYPGVTKVGEKTALKLLNQYGSMENLYANVDDMKKSKLKENLIN  238
            P Q+IDLK+LMGD SDN PGVTK+GEKT+LKLL+++GS+E +Y ++D+ K SK+KENLIN
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  239  DKDSAFLSKQLATIDRDAPLTVDLADVTYAGPDLDKLRDFYTKMNMNSLLKKIGGSVAK-  297
            D+D AFLSK LATI+  +P+T++L D+ Y GPD+  L +FY  M+   L K +++ +++ 
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQE  300

Query  298  PVQAVHFSVLDEQSILALTKLTEPLTFEIEMLEDNYHVAEQIGFFIGTKEETYVSTDITL  357
            PV  + +   +E + ++   ++    F +E L DNYH    IGF  G  E+ Y STD++L
Sbjct  301  PVAVISY---QEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSL  357

Query  358  LTLPAVKRWLEDAKRDLTVFDGKRNIVAANRLGVKLPDIAFDVLLASYLINPDENSNDLG  417
            L+  + K+ ++   + ++ +D KR+ V  ++LG+ L   ++D  LA+YL++  E+ N+L+
Sbjct  358  LATDSFKQVFQ---KPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NELS  413

Query  418  KIAEDHDYHDLPRDEDIYGKGAKRQVPEDDKLFGQFARKSNALFALRPDLTGDLEKQAQT  477
             IA       L  D+ +YGKGAKR VP+ D L+ ++ARK + L+  ++++ + L  + Q 
Sbjct  414  TIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQL  473

Query  478  DLFTDMEMPLSRVLAEMEIQGITLNAKTLKAMGTEFSQSIKILEEKIYAEAGVKFNLNSP  537
            DL+ ++E+PL+ VLA MEI+GI +N  TL+ M+ +    I  L + IY  AG  FN+NSP
Sbjct  474  DLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSP  533

Query  538  KQLGEILFEKLNLP--VIKKTKTGYSTSVDVLNELKSASPIVQDILDYRGWAKLNSTYVV  595
            KQLG ILFEK++LP  + KKTKTGYST+VDVL+ L + +PIV  ILDYR  +KL+STYV+
Sbjct  534  KQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVI  593

Query  596  GLLKAQLPDHKIHTRYLQTLTQTGRLSSVDPNMQNIPAR-DEGKIIRKAFVPSHEGWQIF  654
            GL    L+D KIHTRY+Q LTQTGRLSSVDPN+QNIP R ++G++IRKAF PSHE+  ++
Sbjct  594  GLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLL  653

Query  655  SSDYSQIELRVLSHISGDENMQEAFKHGVDIHANTAMKIFGLSSPDQVTPDMRRQAKATN  714
            SSDYSQIELRVL+HISGDE++  AF++G DIH++TAM++FG+  + +VT++ RR+AKA N
Sbjct  654  SSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVN  713

Query  715  FGIVYGISDYGLSQNIGISRKQAKAFIDGYFDQYPKVHDYMDAMVKKAREDGYVETLFHR  774
            FGIVYGISD+GLS+N+GI+RKQ+K++ID YF++YP +  YM+ +V+ A++ GYVETLF R
Sbjct  714  FGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKR  773

Query  775  RRYLPQIHSRNFNLRKFAERTAMNTPIQGSAADIIKVAMIRMQKALDEAGLQAKMLLQVH  834
            RR LP+I+SRNFN+R FAERTA+N+PIQGSAADI+K+AMI ++KAL+ +G++AKMLLQVH
Sbjct  774  RRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVH  833

Query  835  DELIFEAPEEEIAQLSELVPKVMDSAVHLDVPLKVESHYGPTWFDAK  881
            DE+++E P++E++ +  LV   M++AV+L VPL V+   G +W++AK
Sbjct  834  DEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

160) LBPG_00987 in NC_022112


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  796 bits (3013),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 477/887 (54%), Positives = 677/887 (77%), Gaps = 13/887 (1%)

Query  1    MASKTKLLLVDGNSVAFRAFFALYNQLDRFTNQDGLHTNAIYAFNNMLEIVLKAVQPDAA  60
            M +K KLLL+DG+SVAFRAFFALYNQ+DRF N+ GLHTNAIY+F+ ML+ ++K V+P   
Sbjct  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60

Query  61   LVAFDAGKTTFRTAKYADYKSGRAKTPSELLEQLPYIKELLDDMGIAHYELKDYEADDII  120
            LVAFDAGKTTFRT  YADYK+GRAKTP E+ EQ++YI+E+L  +GIA YEL +YEADDII
Sbjct  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120

Query  121  GTMAKRAD--EAGWETTIVTGdrdltqlttdrttvqvtvKGVNELEAYTPAHVKEKLGIT  178
            GT+ K A+  E   + TIV+GD+DL QLT + T V+++ KGV E+E +TPA + EK+G+T
Sbjct  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180

Query  179  PAQIIDLKGLMGDTSDNYPGVTKVGEKTALKLLNQYGSMENLYANVDDMKKSKLKENLIN  238
            P Q+IDLK+LMGD SDN PGVTK+GEKT+LKLL+++GS+E +Y ++D+ K SK+KENLIN
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  239  DKDNAFLSKQLATIDRDAPLTVDLADVTYAGPDLEKLRDFYTKMNMNSLLKKIGGSVAK-  297
            D+D+AFLSK LATI+  +P+T++L D+ Y GPD+  L +FY  M+   L K +++ +++ 
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQE  300

Query  298  PVQAVHFSVLDEQSILALTKLTEPLTFEIEMLEDNYHVAEQIGFFIGTKEETYVSTDVTL  357
            PV  + +   +E + ++   ++    F +E L DNYH    IGF  G  E+ Y STD++L
Sbjct  301  PVAVISY---QEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSL  357

Query  358  LTLPAVKRWLEDAKRDLTVFDGKRNIVAANRLGVKLPDIAFDVLLASYLINPDENSNDLG  417
            L+  + K+ ++   + ++ +D KR+ V  ++LG+ L   ++D  LA+YL++  E+ N+L+
Sbjct  358  LATDSFKQVFQ---KPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NELS  413

Query  418  KIAEDHDYHDLPRDEDIYGKGAKRQVPEDDKLFGQFARKSNALFALRPDLTGDLEKQAQT  477
             IA       L  D+ +YGKGAKR VP+ D L+ ++ARK + L+  ++++ + L  + Q 
Sbjct  414  TIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQL  473

Query  478  DLFTDMEMPLSRVLAEMEIQGITLNAKTLKAMGTEFSQSIKILEEKIYAEAGVKFNLNSP  537
            DL+ ++E+PL+ VLA MEI+GI +N  TL+ M+ +    I  L + IY  AG  FN+NSP
Sbjct  474  DLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSP  533

Query  538  KQLGEILFEKLNLP--VIKKTKTGYSTSVDVLNELKSASPIVQDILDYRGWAKLNSTYVV  595
            KQLG ILFEK++LP  + KKTKTGYST+VDVL+ L + +PIV  ILDYR  +KL+STYV+
Sbjct  534  KQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVI  593

Query  596  GLLKAQLPDHKIHTRYLQTLTQTGRLSSVDPNMQNIPAR-DEGKIIRKAFVPSHEGWQIF  654
            GL    L+D KIHTRY+Q LTQTGRLSSVDPN+QNIP R ++G++IRKAF PSHE+  ++
Sbjct  594  GLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLL  653

Query  655  SSDYSQIELRVLSHISGDENMQEAFKHGVDIHANTAMKIFGLSSPDQVTPDMRRQAKATN  714
            SSDYSQIELRVL+HISGDE++  AF++G DIH++TAM++FG+  + +VT++ RR+AKA N
Sbjct  654  SSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVN  713

Query  715  FGIVYGISDYGLSQNIGISRKQAKAFIDGYFDQYPKVHDYMDAMVKKAREDGYVETLFHR  774
            FGIVYGISD+GLS+N+GI+RKQ+K++ID YF++YP +  YM+ +V+ A++ GYVETLF R
Sbjct  714  FGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKR  773

Query  775  RRYLPQIHSRNFNLRKFAERTAMNTPIQGSAADIIKVAMIRMQKALDEAGLQAKMLLQVH  834
            RR LP+I+SRNFN+R FAERTA+N+PIQGSAADI+K+AMI ++KAL+ +G++AKMLLQVH
Sbjct  774  RRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVH  833

Query  835  DELIFEAPEEEIAQLSELVPKVMDSAVHLDVPLKVESHYGPTWFDAK  881
            DE+++E P++E++ +  LV   M++AV+L VPL V+   G +W++AK
Sbjct  834  DEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

161) LVIS_1042 in NC_008497


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  795 bits (3009),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 479/893 (54%), Positives = 679/893 (77%), Gaps = 27/893 (3%)

Query  4    KRLLLIDGNSVTFKAFFALYTALGKFTNSEGLHTNAIYGFNTMLETMLKVVQPTHALVAF  63
            ++LLLIDG+SV+F+AFFALY  +++F N  GLHTNAIYGF+ ML+ M+K V+PTH LVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  64   DAGKTTFRTKMYDNYKGGRAKTAPELSEQFPYVKELLAARGIQTYELANYEADDIIGTLA  123
            DAGKTTFRT MY +YK+GRAKT+ E+ EQF+Y++E+L+A GI  YEL +YEADDIIGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  124  KQAE--EQGFTTTIVTGDRDLTQLADDHTTVSISKKGVSEIEHYTPAYVKEKMGVTPAQI  181
            K AE  E  F  TIV+GD+DL QL+D++T V ISKKGV+E+E++TPAY+ EKMG+TP Q+
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  182  IDIKGLQGDNSDNYPGVTGVGPKRAVELVSTYGSIDGIYDHLADITAKKLKEHLIADHDQ  241
            ID+K+L GD+SDN PGVT +G K ++ L+  +GS++GIY+H+ ++ + K+KE+LI D+DQ
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRDQ  244

Query  242  ALLAKQLATIKRDAPVEKTVSELVYKGDDYDQLVPFYQKMNFNQFLSKMSIDGEAPTATP  301
            A+L+K LATI+  +P+   + ++VY+G D   L  FY+ M+F Q+  K ++ ++ P    
Sbjct  245  AFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQL--KKGLASQMPQEPV  302

Query  302  GLEEVTYTVLTADNVTELPS--FTDGCEFYLEMLDDNYHTAELAGFVIGHNDQWWVSRDT  359
            ++  ++Y     ++VT++++  F+    FY+E L DNYH   + GF  GH +Q   S D 
Sbjct  303  AV--ISY-----QEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDL  355

Query  360  ALLQQAPLKGLLENADIAKQVFDAKRTFVALQRLAVTLTGVDCDLLLGSYLLNTYDNSND  419
            +LL   ++K +++++  +   +D KR+ V L +L++ L +   D  L++YLL+T ++ N+
Sbjct  356  SLLATDSFKQVFQKPIAT---YDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NE  411

Query  420  LGRLAMEHGYHQVATDED--VYGKGAKAAIPDDDDVFFSHLARKARAIEQLRPQIFKDLA  477
            L+  ++ + + +++ +ED  VYGKGAK A+PD D V++ HLARK + + + ++Q++  L+
Sbjct  412  LS--TIARIFTDISLEEDDTVYGKGAKRAVPDKD-VLLEHLARKVKVLLDSKSQMLDKLT  468

Query  478  DNEQTDLYRDIELPMAFVLARMEVAGITVEASELEAMGSKFTEQLAEIEQTIYNEAGEEF  537
             +EQ DLY++IELP+A VLA+ME+ GI V+ + L+ M+ +    +  + Q IY+ AG+EF
Sbjct  469  AHEQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEF  528

Query  538  NIGSPKQLGHILFEKMGLP--VIKKTKTGYSTAVGVLEKLAAEAPIAENILKYRKIAKIQ  595
            NI SPKQLG ILFEKM LP  + KKTKTGYSTAV+VLE+LA+ API  +IL YR+I+K+Q
Sbjct  529  NINSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQ  588

Query  596  STYVEGLLKVIHPDDQKVHTRYLQTLTQTGRLSSVDPNLQNIPVRNEEGRAIRKAFVPSH  655
            STYV GL   I +D+ K+HTRY+Q LTQTGRLSSVDPNLQNIP+R E+GR IRKAF PSH
Sbjct  589  STYVIGLQDYILADG-KIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSH  647

Query  656  PDWEIFSSDYSQIELRVLAHMSHDKQMQEAFREGQDIHAATARRIFKMGPDEEVTPNIRR  715
             D  ++SSDYSQIELRVLAH+S D ++  AF EG DIH++TA R+F ++   +VT+N RR
Sbjct  648  EDAVLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRR  707

Query  716  QAKAVNFGIVYGISDFGLSQNIGISRKQAKAFIDTYFEEYPGVKAYTERMVQQAHELGYV  775
            +AKAVNFGIVYGISDFGLS+N+GI+RKQ+K++IDTYFE YPG+KAY E +V++A + GYV
Sbjct  708  NAKAVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYV  767

Query  776  ETIAHRRRYLPDINSRNFNQRSFAERTAMNTPIQGSAADIIKIAMIRMEQALK--DMQAT  833
            ET+  RRR LPDINSRNFN RSFAERTA+N+PIQGSAADI+KIAMI +++AL+  + +A 
Sbjct  768  ETLFKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAK  827

Query  834  MLLQVHDELIFEAPASEIDTLAKLVPSVMDSAIELEIPLKVESHYGPTWYDAK  886
            MLLQVHDE+++E P  E+ ++ KLV   M++A++L +PL V+   G +WY+AK
Sbjct  828  MLLQVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

162) LVISKB_0929 in NC_020819


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  795 bits (3009),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 479/893 (54%), Positives = 679/893 (77%), Gaps = 27/893 (3%)

Query  4    KRLLLIDGNSVTFKAFFALYTALGKFTNSEGLHTNAIYGFNTMLETMLKVVQPTHALVAF  63
            ++LLLIDG+SV+F+AFFALY  +++F N  GLHTNAIYGF+ ML+ M+K V+PTH LVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  64   DAGKTTFRTKMYDNYKGGRAKTAPELSEQFPYVKELLAARGIQTYELANYEADDIIGTLA  123
            DAGKTTFRT MY +YK+GRAKT+ E+ EQF+Y++E+L+A GI  YEL +YEADDIIGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  124  KQAE--EQGFTTTIVTGDRDLTQLADDHTTVSISKKGVSEIEHYTPAYVKEKMGVTPAQI  181
            K AE  E  F  TIV+GD+DL QL+D++T V ISKKGV+E+E++TPAY+ EKMG+TP Q+
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  182  IDIKGLQGDNSDNYPGVTGVGPKRAVELVSTYGSIDGIYDHLADITAKKLKEHLIADHDQ  241
            ID+K+L GD+SDN PGVT +G K ++ L+  +GS++GIY+H+ ++ + K+KE+LI D+DQ
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRDQ  244

Query  242  ALLAKQLATIKRDAPVEKTVSELVYKGDDYDQLVPFYQKMNFNQFLSKMSIDGEAPTATP  301
            A+L+K LATI+  +P+   + ++VY+G D   L  FY+ M+F Q+  K ++ ++ P    
Sbjct  245  AFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQL--KKGLASQMPQEPV  302

Query  302  GLEEVTYTVLTADNVTELPS--FTDGCEFYLEMLDDNYHTAELAGFVIGHNDQWWVSRDT  359
            ++  ++Y     ++VT++++  F+    FY+E L DNYH   + GF  GH +Q   S D 
Sbjct  303  AV--ISY-----QEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDL  355

Query  360  ALLQQAPLKGLLENADIAKQVFDAKRTFVALQRLAVTLTGVDCDLLLGSYLLNTYDNSND  419
            +LL   ++K +++++  +   +D KR+ V L +L++ L +   D  L++YLL+T ++ N+
Sbjct  356  SLLATDSFKQVFQKPIAT---YDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NE  411

Query  420  LGRLAMEHGYHQVATDED--VYGKGAKAAIPDDDDVFFSHLARKARAIEQLRPQIFKDLA  477
            L+  ++ + + +++ +ED  VYGKGAK A+PD D V++ HLARK + + + ++Q++  L+
Sbjct  412  LS--TIARIFTDISLEEDDTVYGKGAKRAVPDKD-VLLEHLARKVKVLLDSKSQMLDKLT  468

Query  478  DNEQTDLYRDIELPMAFVLARMEVAGITVEASELEAMGSKFTEQLAEIEQTIYNEAGEEF  537
             +EQ DLY++IELP+A VLA+ME+ GI V+ + L+ M+ +    +  + Q IY+ AG+EF
Sbjct  469  AHEQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEF  528

Query  538  NIGSPKQLGHILFEKMGLP--VIKKTKTGYSTAVGVLEKLAAEAPIAENILKYRKIAKIQ  595
            NI SPKQLG ILFEKM LP  + KKTKTGYSTAV+VLE+LA+ API  +IL YR+I+K+Q
Sbjct  529  NINSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQ  588

Query  596  STYVEGLLKVIHPDDQKVHTRYLQTLTQTGRLSSVDPNLQNIPVRNEEGRAIRKAFVPSH  655
            STYV GL   I +D+ K+HTRY+Q LTQTGRLSSVDPNLQNIP+R E+GR IRKAF PSH
Sbjct  589  STYVIGLQDYILADG-KIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSH  647

Query  656  PDWEIFSSDYSQIELRVLAHMSHDKQMQEAFREGQDIHAATARRIFKMGPDEEVTPNIRR  715
             D  ++SSDYSQIELRVLAH+S D ++  AF EG DIH++TA R+F ++   +VT+N RR
Sbjct  648  EDAVLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRR  707

Query  716  QAKAVNFGIVYGISDFGLSQNIGISRKQAKAFIDTYFEEYPGVKAYTERMVQQAHELGYV  775
            +AKAVNFGIVYGISDFGLS+N+GI+RKQ+K++IDTYFE YPG+KAY E +V++A + GYV
Sbjct  708  NAKAVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYV  767

Query  776  ETIAHRRRYLPDINSRNFNQRSFAERTAMNTPIQGSAADIIKIAMIRMEQALK--DMQAT  833
            ET+  RRR LPDINSRNFN RSFAERTA+N+PIQGSAADI+KIAMI +++AL+  + +A 
Sbjct  768  ETLFKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAK  827

Query  834  MLLQVHDELIFEAPASEIDTLAKLVPSVMDSAIELEIPLKVESHYGPTWYDAK  886
            MLLQVHDE+++E P  E+ ++ KLV   M++A++L +PL V+   G +WY+AK
Sbjct  828  MLLQVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

163) LSEI_1709 in NC_008526


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  795 bits (3010),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 478/887 (54%), Positives = 676/887 (77%), Gaps = 13/887 (1%)

Query  1    MASKTKLLLVDGNSVAFRAFFALYNQLDRFTNQDGLHTNAIYAFNNMLEIVLKAVQPDAA  60
            M +K KLLL+DG+SVAFRAFFALYNQ+DRF N+ GLHTNAIY+F+ ML+ ++K V+P   
Sbjct  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60

Query  61   LVAFDAGKTTFRTAKYADYKSGRAKTPSELLEQLPYIKELLDDMGIAHYELKDYEADDII  120
            LVAFDAGKTTFRT  YADYK+GRAKTP E+ EQ++YI+E+L  +GIA YEL +YEADDII
Sbjct  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120

Query  121  GTMAKRAD--EAGWETTIVTGdrdltqlttdrttvqvtvKGVNELEAYTPAHVKEKLGIT  178
            GT+ K A+  E   + TIV+GD+DL QLT + T V+++ KGV E+E +TPA + EK+G+T
Sbjct  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180

Query  179  PAQIIDLKGLMGDTSDNYPGVTKVGEKTALKLLNQYGSMENLYANVDDMKKSKLKENLIN  238
            P Q+IDLK+LMGD SDN PGVTK+GEKT+LKLL+++GS+E +Y ++D+ K SK+KENLIN
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  239  DKDNAFLSKQLATIDRDVPLTVDLADVTYAGPDLDKLRDFYTKMNMNSLLKKIGGSVAK-  297
            D+D+AFLSK LATI+   P+T++L D+ Y GPD+  L +FY  M+   L K +++ +++ 
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQE  300

Query  298  PVQAVHFSVLDEQSILALTKLTEPLTFEIEMLEDNYHVAEQIGFFIGTKEETYVSTDVTL  357
            PV  + +   +E + ++   ++    F +E L DNYH    IGF  G  E+ Y STD++L
Sbjct  301  PVAVISY---QEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSL  357

Query  358  LTLPAVKRWLEDAKRDLTVFDGKRNIVAANRLGVKLPDIAFDVLLASYLINPDENSNDLG  417
            L+  + K+ ++   + ++ +D KR+ V  ++LG+ L   ++D  LA+YL++  E+ N+L+
Sbjct  358  LATDSFKQVFQ---KPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NELS  413

Query  418  KIAEDHDYHDLPRDEDIYGKGAKRQVPEDDKLFGQFARKSDALFALRPDLTGDLEKQEQT  477
             IA       L  D+ +YGKGAKR VP+ D L+ ++ARK   L+  ++++ + L  +EQ 
Sbjct  414  TIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQL  473

Query  478  DLFTDMEMPLSRVLAEMEIQGITLNAKTLKAMGTEFSQSIKILEEKIYAEAGVKFNLNSP  537
            DL+ ++E+PL+ VLA MEI+GI +N  TL+ M+ +    I  L + IY  AG  FN+NSP
Sbjct  474  DLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSP  533

Query  538  KQLGEILFEKLNLP--VIKKTKTGYSTSVDVLNELKSASPIVQDILDYRGWAKLNSTYVV  595
            KQLG ILFEK++LP  + KKTKTGYST+VDVL+ L + +PIV  ILDYR  +KL+STYV+
Sbjct  534  KQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVI  593

Query  596  GLLKAQLPDHKIHTRYLQTLTQTGRLSSVDPNMQNIPAR-DEGKIIRKAFVPSHEGWQIF  654
            GL    L+D KIHTRY+Q LTQTGRLSSVDPN+QNIP R ++G++IRKAF PSHE+  ++
Sbjct  594  GLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLL  653

Query  655  SSDYSQIELRVLSHISGDENMQEAFKHGVDIHANTAMKIFGLSSPDQVTPDMRRQAKATN  714
            SSDYSQIELRVL+HISGDE++  AF++G DIH++TAM++FG+  + +VT++ RR+AKA N
Sbjct  654  SSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVN  713

Query  715  FGIVYGISDYGLSQNIGISRKQAKAFIDGYFDQYPKVHDYMDAMVKKAREDGYVETLFHR  774
            FGIVYGISD+GLS+N+GI+RKQ+K++ID YF++YP +  YM+ +V+ A++ GYVETLF R
Sbjct  714  FGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKR  773

Query  775  RRYLPQIHSRNFNLRKFAERTAMNTPIQGSAADIIKVAMIRMQKALDEAGLQAKMLLQVH  834
            RR LP+I+SRNFN+R FAERTA+N+PIQGSAADI+K+AMI ++KAL+ +G++AKMLLQVH
Sbjct  774  RRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVH  833

Query  835  DELIFEAPEEEIAQLSELVPKVMDSAVHLDVPLKVESHYGPTWFDAK  881
            DE+++E P++E++ +  LV   M++AV+L VPL V+   G +W++AK
Sbjct  834  DEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

164) LOCK919_1880 in NC_021721


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  795 bits (3008),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 477/887 (54%), Positives = 675/887 (77%), Gaps = 13/887 (1%)

Query  1    MASKTKLLLVDGNSVAFRAFFALYNQLDRFTNQDGLHTNAIYAFNNMLEIVLKAVQPDAA  60
            M +K KLLL+DG+SVAFRAFFALYNQ+DRF N+ GLHTNAIY+F+ ML+ ++K V+P   
Sbjct  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60

Query  61   LVAFDAGKTTFRTAKYADYKSGRAKTPSELLEQLPYIKELLDDMGIAHYELKDYEADDII  120
            LVAFDAGKTTFRT  YADYK+GRAKTP E+ EQ++YI+E+L  +GIA YEL +YEADDII
Sbjct  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120

Query  121  GTMAKRAD--EAGWETTIVTGdrdltqlttdrttvqvtvKGVNELEAYTPAHVKEKLGIT  178
            GT+ K A+  E   + TIV+GD+DL QLT + T V+++ KGV E+E +TPA + EK+G+T
Sbjct  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180

Query  179  PAQIIDLKGLMGDTSDNYPGVTKVGEKTALKLLNQYGSMENLYANVDDMKKSKLKENLIN  238
            P Q+IDLK+LMGD SDN PGVTK+GEKT+LKLL+++GS+E +Y ++D+ K SK+KENLIN
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  239  DKDNAFLSKQLATIDRDAPLTVDLADVTYAGPDLDKLRDFYTKMNMNSLLKKIGGSVAK-  297
            D+D+AFLSK LATI+  +P+T++L D+ Y GPD+  L +FY  M+   L K +++ +++ 
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQE  300

Query  298  PVQAVHFSVLDEQSILALTKLTEPLTFEIEMLEDNYHVAEQIGFFIGTKEETYVSTDVTL  357
            PV  + +   +E + ++   ++    F +E L DNYH    IGF  G  E+ Y STD++L
Sbjct  301  PVAVISY---QEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSL  357

Query  358  LTLPAVKRWLEDAKRDLTVFDGKRNIVAANRLGVKLPDIAFDVLLASYLINPDENSNDLG  417
            L+  + K+ ++   + ++ +D KR+ V  ++LG+ L   ++D  LA+YL++  E+ N+L+
Sbjct  358  LATDSFKQVFQ---KPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NELS  413

Query  418  KIAEDHDYHDLPRDEDIYGKGAKRQVPEDDKLFGQFARKSDALFALRPDLTGDLEKQAQT  477
             IA       L  D+ +YGKGAKR VP+ D L+ ++ARK   L+  ++++ + L  + Q 
Sbjct  414  TIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQL  473

Query  478  DLFTDMEMPLSRVLAEMEIQGITLNAKTLKAMGTEFSQSIKILEEKIYAEAGVKFNLNSP  537
            DL+ ++E+PL+ VLA MEI+GI +N  TL+ M+ +    I  L + IY  AG  FN+NSP
Sbjct  474  DLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSP  533

Query  538  KQLGEILFEKLNLP--VIKKTKTGYSTSVDVLNELKSASPIVQDILDYRGWAKLNSTYVV  595
            KQLG ILFEK++LP  + KKTKTGYST+VDVL+ L + +PIV  ILDYR  +KL+STYV+
Sbjct  534  KQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVI  593

Query  596  GLLKAQLPDHKIHTRYLQTLTQTGRLSSVDPNMQNIPAR-DEGKIIRKAFVPSHEGWQIF  654
            GL    L+D KIHTRY+Q LTQTGRLSSVDPN+QNIP R ++G++IRKAF PSHE+  ++
Sbjct  594  GLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLL  653

Query  655  SSDYSQIELRVLSHISGDENMQEAFKHGVDIHANTAMKIFGLSSPDQVTPDMRRQAKATN  714
            SSDYSQIELRVL+HISGDE++  AF++G DIH++TAM++FG+  + +VT++ RR+AKA N
Sbjct  654  SSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVN  713

Query  715  FGIVYGISDYGLSQNIGISRKQAKAFIDGYFDQYPKVHDYMDAMVKKAREDGYVETLFHR  774
            FGIVYGISD+GLS+N+GI+RKQ+K++ID YF++YP +  YM+ +V+ A++ GYVETLF R
Sbjct  714  FGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKR  773

Query  775  RRYLPQIHSRNFNLRKFAERTAMNTPIQGSAADIIKVAMIRMQKALDEAGLQAKMLLQVH  834
            RR LP+I+SRNFN+R FAERTA+N+PIQGSAADI+K+AMI ++KAL+ +G++AKMLLQVH
Sbjct  774  RRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVH  833

Query  835  DELIFEAPEEEIVQLSELVPKVMDSAVHLDVPLKVESHYGPTWFDAK  881
            DE+++E P++E+  +  LV   M++AV+L VPL V+   G +W++AK
Sbjct  834  DEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

165) LCAZH_1699 in NC_014334


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  795 bits (3008),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 477/887 (54%), Positives = 675/887 (77%), Gaps = 13/887 (1%)

Query  1    MASKTKLLLVDGNSVAFRAFFALYNQLDRFTNQDGLHTNAIYAFNNMLEIVLKAVQPDAA  60
            M +K KLLL+DG+SVAFRAFFALYNQ+DRF N+ GLHTNAIY+F+ ML+ ++K V+P   
Sbjct  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60

Query  61   LVAFDAGKTTFRTAKYADYKSGRAKTPSELLEQLPYIKELLDDMGIAHYELKDYEADDII  120
            LVAFDAGKTTFRT  YADYK+GRAKTP E+ EQ++YI+E+L  +GIA YEL +YEADDII
Sbjct  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120

Query  121  GTMAKRAD--EAGWETTIVTGdrdltqlttdrttvqvtvKGVNELEAYTPAHVKEKLGIT  178
            GT+ K A+  E   + TIV+GD+DL QLT + T V+++ KGV E+E +TPA + EK+G+T
Sbjct  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180

Query  179  PAQIIDLKGLMGDTSDNYPGVTKVGEKTALKLLNQYGSMENLYANVDDMKKSKLKENLIN  238
            P Q+IDLK+LMGD SDN PGVTK+GEKT+LKLL+++GS+E +Y ++D+ K SK+KENLIN
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  239  DKDNAFLSKQLATIDRDAPLTVDLADVTYAGPDLDKLRDFYTKMNMNSLLKKIGGSVAK-  297
            D+D+AFLSK LATI+  +P+T++L D+ Y GPD+  L +FY  M+   L K +++ +++ 
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQE  300

Query  298  PVQAVHFSVLDEQSILALTKLTEPLTFEIEMLEDNYHVAEQIGFFIGTKEETYVSTDVTL  357
            PV  + +   +E + ++   ++    F +E L DNYH    IGF  G  E+ Y STD++L
Sbjct  301  PVAVISY---QEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSL  357

Query  358  LTLPAVKRWLEDAKRDLTVFDGKRNIVAANRLGVKLPDIAFDVLLASYLINPDENSNDLG  417
            L+  + K+ ++   + ++ +D KR+ V  ++LG+ L   ++D  LA+YL++  E+ N+L+
Sbjct  358  LATDSFKQVFQ---KPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NELS  413

Query  418  KIAEDHDYHDLPRDEDIYGKGAKRQVPEDDKLFGQFARKSDALFALRPDLTGDLEKQAQT  477
             IA       L  D+ +YGKGAKR VP+ D L+ ++ARK   L+  ++++ + L  + Q 
Sbjct  414  TIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQL  473

Query  478  DLFTDMEMPLSRVLAEMEIQGITLNAKTLKAMGTEFSQSIKILEEKIYAEAGVKFNLNSP  537
            DL+ ++E+PL+ VLA MEI+GI +N  TL+ M+ +    I  L + IY  AG  FN+NSP
Sbjct  474  DLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSP  533

Query  538  KQLGEILFEKLNLP--VIKKTKTGYSTSVDVLNELKSASPIVQDILDYRGWAKLNSTYVV  595
            KQLG ILFEK++LP  + KKTKTGYST+VDVL+ L + +PIV  ILDYR  +KL+STYV+
Sbjct  534  KQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVI  593

Query  596  GLLKAQLPDHKIHTRYLQTLTQTGRLSSVDPNMQNIPAR-DEGKIIRKAFVPSHEGWQIF  654
            GL    L+D KIHTRY+Q LTQTGRLSSVDPN+QNIP R ++G++IRKAF PSHE+  ++
Sbjct  594  GLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLL  653

Query  655  SSDYSQIELRVLSHISGDENMQEAFKHGVDIHANTAMKIFGLSSPDQVTPDMRRQAKATN  714
            SSDYSQIELRVL+HISGDE++  AF++G DIH++TAM++FG+  + +VT++ RR+AKA N
Sbjct  654  SSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVN  713

Query  715  FGIVYGISDYGLSQNIGISRKQAKAFIDGYFDQYPKVHDYMDAMVKKAREDGYVETLFHR  774
            FGIVYGISD+GLS+N+GI+RKQ+K++ID YF++YP +  YM+ +V+ A++ GYVETLF R
Sbjct  714  FGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKR  773

Query  775  RRYLPQIHSRNFNLRKFAERTAMNTPIQGSAADIIKVAMIRMQKALDEAGLQAKMLLQVH  834
            RR LP+I+SRNFN+R FAERTA+N+PIQGSAADI+K+AMI ++KAL+ +G++AKMLLQVH
Sbjct  774  RRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVH  833

Query  835  DELIFEAPEEEIVQLSELVPKVMDSAVHLDVPLKVESHYGPTWFDAK  881
            DE+++E P++E+  +  LV   M++AV+L VPL V+   G +W++AK
Sbjct  834  DEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

166) lhv_1617 in NC_010080


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  789 bits (2985),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 475/890 (54%), Positives = 675/890 (76%), Gaps = 20/890 (2%)

Query  4    EKLLLIDGNSVAFRAFYALYRQLESFKSPDGLHTNAIYAFKNMLDVLLKDVDPTHVLVAF  63
            +KLLLIDG+SVAFRAF+ALY Q++ FK+  GLHTNAIY+F  MLD ++K V PTHVLVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  64   DAGKVTFRTKMYGEYKGGRAKTPEELLEQMPYIQEMLHDLGIKTYELKNYEADDIIGTFA  123
            DAGK TFRT MY++YK+GRAKTP+E+ EQ +YI+EML  LGI  YEL +YEADDIIGT+ 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  124  AKGEKAG--FTTTIVTGDRDLTQLASDKTTVEVTKSGVSKLEAYTPEHMKEVNGVTPSEF  181
              +E++   F  TIV+GD+DL QL+ ++T VE++K GV+ +E +TP  + E  G+TP++F
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  182  IDMKALMGDNSDNYPGVEGIGPKTASNLIQEYGSVENLYDHIDEMKKSKRKERLIRDKEK  241
            ID+KALMGD+SDN PGV  IG KT+ +L++E+GS+E +Y+HID  K SK KE LI D+++
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRDQ  244

Query  242  AFLAKKLATIDRDSPVTLDIDDIKRQPVDYEKLRQFYEKMNFRKFLADLNASGAGQDSTE  301
            AFL+K LATI+  SP+T+++DDI  +  D   L QFY+ M+F ++  +L AS   Q++  
Sbjct  245  AFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGL-ASQMPQEPVA  303

Query  302  VEKVEYIVLNDDNVKDVKAT--EADTIEFYLEMLGANYHLAPFVGFSLKINDKIYVSRDV  359
            V  + Y     ++V +V A    A+ I FY+E L  NYH  +++GF+    ++IY S D+
Sbjct  304  V--ISY-----QEVTNVSADLFSAEDI-FYFETLRDNYHREAIIGFAWGHGEQIYASTDL  355

Query  360  ELLEEDNIKHILEDEKIKKNVFDLKRTMVAAHRLGIHTHGLDYDMLLASYLINNENNSND  419
             LL  D++K++++        +D+KR+ V   +LGI+  +  YD  LA+YL++  ++ N+
Sbjct  356  SLLATDSFKQVFQKPI---ATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NE  411

Query  420  LGEIAHLYGDYSVKTDLEVYGKGKSEHIPDDDDELFNHLASKVNAIESlkktlleklkDH  479
            L+ IA+++ D S+  D  VYGKG    +PD D  L++HLA KV+ +   K  +L+KL  H
Sbjct  412  LSTIARIFTDISLEEDDTVYGKGAKRAVPDKD-VLLEHLARKVKVLLDSKSQMLDKLTAH  470

Query  480  EQDALFDTIEIPTARVLARMEMNGMKVEASTLIQLQNEFAVKLKKLEDKIYGQAGEKFNL  539
            EQ  L++ IE+P A VLA+ME++G+KV+ +TL ++ ++  V +  L + IY+ AG+ FN+
Sbjct  471  EQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNI  530

Query  540  NSPKQLGHILFEKLGLPV--IKKTKTGYSTSVEVLDQLKTQSPIVSKILDYRQIAKIQST  597
            NSPKQLG ILFEK+ LP+   KKTKTGYST+V+VL++L   +PIV+KILDYRQI+K+QST
Sbjct  531  NSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQST  590

Query  598  YVKGLLDVIQPDGRVHTRYLQTLTATGRLSSVDPNLQNIPTRTEEGKQIRKAFVPSEPDG  657
            YV GL D I +DG++HTRY+Q LT TGRLSSVDPNLQNIP R E+G+ IRKAF PS+ D+
Sbjct  591  YVIGLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDA  650

Query  658  YIFSCDYSQVELRVLAHVSGDQNMQEAFKTGYDIHSHTAMKIFHLESPDEVTPLMRRHAK  717
             ++S DYSQ+ELRVLAH+SGD+++  AF+ G DIH+ TAM++F ++ + +VT+  RR+AK
Sbjct  651  VLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAK  710

Query  718  AVNFGIVYGISDYGLSKNLGISRKRAQEFIDNYFEQYPQIKDYMNKAVQEARDKGYAETI  777
            AVNFGIVYGISD+GLS+NLGI+RK+++ +ID YFE+YP IK YM++ V+EA+DKGY ET+
Sbjct  711  AVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETL  770

Query  778  MHRRRYLPDIHAKKYTVRAFAERTAINSPIQGSAADIIKIAMINMQKKLDELHLKTKMVI  837
              RRR LPDI+++++ VR+FAERTAINSPIQGSAADI+KIAMIN++K L+   +++KM++
Sbjct  771  FKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLL  830

Query  838  QVHDELIFDVPKDELETIKKIVPEVMQSAVKLDVPLIADSGWGHNWYDAK  887
            QVHDE++++VP+DEL +IKK+V + M++AV L VPL  D + G++WY+AK
Sbjct  831  QVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

167) LDBND_1445 in NC_014727


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  788 bits (2984),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 473/891 (54%), Positives = 666/891 (75%), Gaps = 18/891 (2%)

Query  2    NKKKLLLIDGNSVAFRAFFAMYQQLDKFKNPEGLHTNALYAFKNMLDVVLKQEDPSHILV  61
            NK+KLLLIDG+SVAFRAFFA+Y+Q+D+FKN  GLHTNA+Y+F  MLD ++K+  P+H+LV
Sbjct  3    NKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLV  62

Query  62   AFDAGKTTFRTAMYKDYKGGRDKTPAELSEQLPYLREMLKDMGIKSYELANYEADDIIGT  121
            AFDAGKTTFRT MY DYK+GR KTP E+ EQ++Y+REML  +GI  YEL +YEADDIIGT
Sbjct  63   AFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGT  122

Query  122  MAKKG--AEAGYEVAVVSGDKDLTQLASDHVTVYVTKSGVTKLEAFTPDHMKEVNGVTPT  179
            + K +  +E  ++V++VSGDKDL QL+ ++  V ++K GV+ +E FTP  + E  G+TP 
Sbjct  123  LDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPN  182

Query  180  EFIDMKALMGDPSDNYPGVAKVGPKTAFKLIQEYGSVENLYNHVDEMKKSKLKENLIASK  239
            +FID+KALMGD SDN PGV+K+G KT++KL++E+GS+E +Y+H+D  K SK+KENLI  +
Sbjct  183  QFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDR  242

Query  240  DNALLGKKLATINCDSPVEVTLDDLSYEGSNIDDLRRFYEKMNFRRFLADLAQKGELTEN  299
            D+A+L+K LATIN  SP+ + LDD+ Y+G+++  L +FY+ M+F ++  +LA  +++ ++
Sbjct  243  DQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLA--SQMPQE  300

Query  300  KTEVKK-QDYVVLSADNLDQLPKAAEVTFYLAMFGDNYHLADFAGFALKIGGETFVSRDV  358
               V   Q+   +SAD +     +AE  FY+  + DNYH   + GFA   G + + S D+
Sbjct  301  PVAVISYQEVTNVSADLF-----SAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDL  355

Query  359  FLLQESPLKGMLEDSAVQKNVFDLKRTTYGLYRLGIKAESLTFDLLLASYLVDNEKNSND  418
             LL   ++K +++ +      +D+KR+   L +LGI   + ++D  LA+YL+    + N+
Sbjct  356  SLLATDSFKQVFQKPI---ATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTV-EDNE  411

Query  419  LGELVQGYDYFDLKTDLEVYGKGKNAKIPADDAVFFNHLAGKTAAIAALKDSLLKQLKDH  478
            L+ + + +  + L  D  VYGKG +  +P  D V+++HLA K   +   K  +L +L  H
Sbjct  412  LSTIARIFTDISLEEDDTVYGKGAKRAVPDKD-VLLEHLARKVKVLLDSKSQMLDKLTAH  470

Query  479  EQDDLYDSIELPTARVLAKMEMNGIKVQPSRLKELENDFAVRLKELEEKIYKEAGEEFNL  538
            EQ DLY++IELP A VLAKME++GIKV+ + L+++ ++  V +  L + IY  AG+EFN+
Sbjct  471  EQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNI  530

Query  539  NSPKQLGVILFEKLGLP--VIKKTKTGYSTSVEVLNQLKEQSPVVSDILEYRQISKIQST  596
            NSPKQLG ILFEK+ LP  + KKTKTGYST+V+VL++L   +P+V+ IL+YRQI+K+QST
Sbjct  531  NSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQST  590

Query  597  YVKGLLDVIDERDGRIHTRYLQTLTATGRLSSVDPNLQNIPTRTEEGKQIRKAFVPSSPD  656
            YV GL D I   DG+IHTRY+Q LT TGRLSSVDPNLQNIP R E+G+ IRKAF PS  D
Sbjct  591  YVIGLQDYILA-DGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHED  649

Query  657  GYIYSCDYSQIELRVLAHVSADPNMQEAFKTGYDIHAHTAMKIFHLSSVDEVTSLQRRRA  716
            + + S DYSQIELRVLAH+S+D ++  AF+ G DIH+ TAM++F +    +VT+ +RR A
Sbjct  650  AVLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNA  709

Query  717  KAVNFGIVYGISDYGLSKNLDISRKQAKEFIDEYFEQYPGIQAYMDRAVKDAREKGYAET  776
            KAVNFGIVYGISD+GLS+NL+I+RKQ+K +ID YFE+YPGI+AYM+  V++A++KGY ET
Sbjct  710  KAVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVET  769

Query  777  IMHRRRYLPDIHAKNFNVRSFAERTAINSPIQGSAADIMKIAMINMQKKLDELGLKTKMV  836
            +  RRR LPDI+++NFNVRSFAERTAINSPIQGSAADI+KIAMIN++K L+  G+++KM+
Sbjct  770  LFKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKML  829

Query  837  VQVHDELIFDVPADELETIQKIVPSVMQAAVKLDVPLVADAGWGHDWYEAK  887
            +QVHDE++++VP DEL +I+K+V   M+AAV L VPL  D + G+ WYEAK
Sbjct  830  LQVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

168) polA in NC_013504


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  787 bits (2979),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 485/889 (55%), Positives = 679/889 (77%), Gaps = 15/889 (1%)

Query  2    AQKKLLLIDGNSVAFRAFYALYRQLDRFTSPDGLHTNAIFTFKNMLDAIMKQTNPTNVLV  61
             ++KLLLIDG+SVAFRAF+ALY Q+DRF +  GLHTNAI+ F  MLD +MK+  PT+VLV
Sbjct  3    NKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLV  62

Query  62   AFDAGKVTFRTEMYQDYKGGRQKTPSELSEQLPVIREMLKDLGIKSYELKNYEADDIIGT  121
            AFDAGK TFRTEMY DYK+GR KTP E+ EQ++ IREML  LGI  YEL +YEADDIIGT
Sbjct  63   AFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGT  122

Query  122  LSKMGE--DAGYTVDIVTGDRDLTQLASDKTTVLITKNGVGDTEAYTPDHMKEVNGVTPT  179
            L KM+E  +  + V IV+GD+DL QL+ ++T V I+K+GV++ E +TP  + E  G+TP 
Sbjct  123  LDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPN  182

Query  180  EFIDMKALMGDSSDNYPGVTKVGPKTASRLIQKYGSIEELYEHVDEMKKSKLKENLINdk  239
            +FID+KALMGD SDN PGVTK+G KT+ +L++ +GS+E +YEH+D  K SK+KENLIND+
Sbjct  183  QFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDR  242

Query  240  dkaflakklaTIDRDSPVEVNLADTKLQEPNIEDLRNLYERLGFKKFLAELGSTGTTSSE  299
            D+AFL+K LATI+  SP+ + L D   + P++  L ++Y+ ++F ++   L+S     ++
Sbjct  243  DQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQ---MPQ  299

Query  300  QEIEKYEYLELTNENIVELDKISEKEVTFYLAMLGDNYHLAPIEGFSLKVGNKIYVSKDP  359
            + +    Y E+TN   V  D +S  ++ FY+  L DNYH  +I GF+   G++IY S D 
Sbjct  300  EPVAVISYQEVTN---VSADLFSAEDI-FYFETLRDNYHREAIIGFAWGHGEQIYASTDL  355

Query  360  VLLQENPLRKMLEDKTIKKNVFDIKRTYVGLHRLNLKAEGLDYDMLLASYLVNNENNSND  419
             LL  ++++++++ K I    +D+KR+ V L +L +   +  YD  LA+YL++  ++ N+
Sbjct  356  SLLATDSFKQVFQ-KPI--ATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NE  411

Query  420  LGEVAHLYDDYSVKTDLEVYGKGKKQAVPDDNEFFEHLAAKVAVIeklktplleklkDHE  479
            L+ +A+++ D S+  D  VYGKG K+AVPD + ++EHLA KV V+   K+ +L+KL  HE
Sbjct  412  LSTIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHE  471

Query  480  QDDLYETIEIPVAFVLAKMEITGIKVEASVLNQLGNDFAVKLQELEHKIYQQAGEEFNLN  539
            Q DLY+ IE+P+A VLAKMEI GIKV+ + L++++++  V ++ L + IY+ AG+EFN+N
Sbjct  472  QLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNIN  531

Query  540  SPKQLGHILFEKLGLP--PIKKTKTGYSTSVEVLEQLKMKSPIVSEILDYRQIAKIQNTY  597
            SPKQLG ILFEK+ LP    KKTKTGYST+V+VLE+L   +PIV+ ILDYRQI+K+Q+TY
Sbjct  532  SPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTY  591

Query  598  VKGLLECIQPDGRIHTRYLQTLTATGRLSSVDPNLQNIPTRTNEGKQIRKAFVPSTKDGY  657
            V GL + I +DG+IHTRY+Q LT TGRLSSVDPNLQNIP R ++G+ IRKAF PS  D+ 
Sbjct  592  VIGLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAV  651

Query  658  IFSCDYSQVELRVLAHVSGDEHMQEAFKSGYDIHAHTAMKIFHLDSPDEVTPLMRRHAKA  717
            ++S DYSQ+ELRVLAH+SGDEH+  AF+ G DIH+ TAM++F +D + +VT+  RR+AKA
Sbjct  652  LLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKA  711

Query  718  VNFGIVYGISDYGLSKNLGISRKQAKTFIENYFEQYPQIKNYMDDAIKKARENGYAETIM  777
            VNFGIVYGISD+GLS+NLGI+RKQ+K++I+ YFE+YP IK YM++ ++ A+++GY ET+ 
Sbjct  712  VNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLF  771

Query  778  HRRRYLPDIHSKNFNVRSFAERTAINSPIQGSAADIIKIAMINMQKKLDELHLKTKMVLQ  837
             RRR LPDI+S+NFNVRSFAERTAINSPIQGSAADI+KIAMIN++K L+   +++KM+LQ
Sbjct  772  KRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQ  831

Query  838  VHDELIFDVPKDELDTIKKIVPEVMQSAVKLDVPLIADSNWGHNWYDAK  886
            VHDE++++VP+DEL +IKK+V + M++AV L VPL  D + G++WY+AK
Sbjct  832  VHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

169) LBU_1297 in NC_017469


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  787 bits (2977),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 472/890 (54%), Positives = 665/890 (75%), Gaps = 18/890 (2%)

Query  2    NKKLLLIDGNSVAFRAFFAMYQQLDKFKNPEGLHTNALYAFKNMLDVVLKQEDPSHILVA  61
            ++KLLLIDG+SVAFRAFFA+Y+Q+D+FKN  GLHTNA+Y+F  MLD ++K+  P+H+LVA
Sbjct  4    KNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVA  63

Query  62   FDAGKTTFRTAMYKDYKGGRDKAPAELSEQFPYLREMLKDMGIKSYELANYEADDIIGTM  121
            FDAGKTTFRT MY DYK+GR K+P E+ EQF+Y+REML  +GI  YEL +YEADDIIGT+
Sbjct  64   FDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTL  123

Query  122  AKKG--AEAGYEVAVVSGDKDLTQLASDHVTVYVTKSGVTKLEAFTPDHMKEVNGVTPTE  179
             K +  +E  ++V++VSGDKDL QL+ ++  V ++K GV+ +E FTP  + E  G+TP +
Sbjct  124  DKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQ  183

Query  180  FIDMKALMGDPSDNYPGVAKVGPKTASKLIQEYGSVENLYDHVDEMKKSKLKENLIAGKD  239
            FID+KALMGD SDN PGV+K+G KT+ KL++E+GS+E +Y+H+D  K SK+KENLI ++D
Sbjct  184  FIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRD  243

Query  240  NALLGKKLATIKCDSPVEVTLDDLSYEGSNVDDLRRFYEKMNFRRFLADLAQKGELTENK  299
            +A+L+K LATI+  SP+ + LDD+ Y+G++V  L +FY+ M+F ++  +LA  +++ ++ 
Sbjct  244  QAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLA--SQMPQEP  301

Query  300  TEVKK-QDYVVLSADNLDQLPKAAEVTFYLAMFGDNYHLADFAGFALKIGGETFVSRDVF  358
              V   Q+   +SAD +     +AE  FY+  + DNYH   + GFA   G + + S D+ 
Sbjct  302  VAVISYQEVTNVSADLF-----SAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLS  356

Query  359  LLQESPLKEMLEDSAVQKNVFDLKRTTYGLYRLGIKAEGLSFDLLLASYLVDNEKNSNDL  418
            LL   ++K++++ +      +D+KR+   L +LGI   + S+D  LA+YL+    + N+L
Sbjct  357  LLATDSFKQVFQKPI---ATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTV-EDNEL  412

Query  419  GELVQGYDYYDLKTDLEVYGKGKNAKIPADDAVFFNHLAGKTAAIAALKDSLLKQLKDHE  478
            + + + +    L  D  VYGKG +  +P  D V+++HLA K   +   K  +L +L  HE
Sbjct  413  STIARIFTDISLEEDDTVYGKGAKRAVPDKD-VLLEHLARKVKVLLDSKSQMLDKLTAHE  471

Query  479  QDDLYDSIELPTARVLAKMEMNGIKVQPSRLKELENDFAVRLKELEEKIYKEAGEEFNLN  538
            Q DLY++IELP A VLAKME++GIKV+ + L+++ ++  V +  L + IY  AG+EFN+N
Sbjct  472  QLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNIN  531

Query  539  SPKQLGVILFEKLGLP--VIKKTKTGYSTSVEVLNQLKEQSPVVSDILEYRQISKIQSTY  596
            SPKQLG ILFEK+ LP  + KKTKTGYST+V+VL++L   +P+V+ IL+YRQI+K+QSTY
Sbjct  532  SPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTY  591

Query  597  VKGLLDVIDERDGRIHTRYLQTLTATGRLSSVDPNLQNIPTRTEEGKQIRKAFVPSSPDG  656
            V GL D I   DG+IHTRY+Q LT TGRLSSVDPNLQNIP R E+G+ IRKAF PS  D+
Sbjct  592  VIGLQDYILA-DGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDA  650

Query  657  YIYSCDYSQIELRVLAHVSADPNMQEAFKTGYDIHAHTAMKIFHLSSVDEVTSLQRRRAK  716
             + S DYSQIELRVLAH+S+D ++  AF+ G DIH+ TAM++F +    +VT+ +RR AK
Sbjct  651  VLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAK  710

Query  717  AVNFGIVYGISDYGLSKNLDISRKQAKEFIDEYFDQYPGIQAYMDWAVKDAREKGYAETI  776
            AVNFGIVYGISD+GLS+NL+I+RKQ+K +ID YF++YPGI+AYM+  V++A++KGY ET+
Sbjct  711  AVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETL  770

Query  777  MHRRRYLPDIHAKNFNVRSFAERTAINSPIQGSAADIMKIAMINMQKKLDELGLKTKMVV  836
              RRR LPDI+++NFNVRSFAERTAINSPIQGSAADI+KIAMIN++K L+  G+++KM++
Sbjct  771  FKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLL  830

Query  837  QVHDELIFDVPADELETIQKIVPSVMQAAVKLDVPLVADASWGHDWYEAK  886
            QVHDE++++VP DEL +I+K+V   M+AAV L VPL  D S G+ WYEAK
Sbjct  831  QVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

170) LJ1651 in NC_005362


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  786 bits (2974),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 491/891 (56%), Positives = 681/891 (77%), Gaps = 19/891 (2%)

Query  2    AQKKLLLIDGNSVAFRAFYALYRQLDRFTSPDGLHTNAIFTFKNMLDAIMKQTNPTNVLV  61
             ++KLLLIDG+SVAFRAF+ALY Q+DRF +  GLHTNAI+ F  MLD +MK+  PT+VLV
Sbjct  3    NKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLV  62

Query  62   AFDAGKVTFRTEMYQDYKGGRQKTPSELSEQLPVIREMLKDLGIKSYELKNYEADDIIGT  121
            AFDAGK TFRTEMY DYK+GR KTP E+ EQ++ IREML  LGI  YEL +YEADDIIGT
Sbjct  63   AFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGT  122

Query  122  LSKMGE--DAGYTVDIVTGDRDLTQLASDKTTVLITKNGVGDTEAYTPAHMKEVNGVTPT  179
            L KM+E  +  + V IV+GD+DL QL+ ++T V I+K+GV++ E +TPA + E  G+TP 
Sbjct  123  LDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPN  182

Query  180  EFIDMKALMGDSSDNYPGVTKVGPKTASRLIQKYGSIEELYEHVDEMKKSKLKENLINdk  239
            +FID+KALMGD SDN PGVTK+G KT+ +L++ +GS+E +YEH+D  K SK+KENLIND+
Sbjct  183  QFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDR  242

Query  240  dkaflakklaTIDRDSPVEVTLADTKLQEPNIEDLRNLYERLGFKKFLAELDVNGTTSNT  299
            D+AFL+K LATI+  SP+ + L D   + P++  L ++Y+ ++F     +L  +G +S+ 
Sbjct  243  DQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDF----VQLK-KGLASQM  297

Query  300  PE--TEKYEYLELTKENIIELDKISEKEVTFYLAMLGDNYHLAPIEGFSLKVGNKIYVSK  357
            P+       Y E+T+   +  D +S  ++ FY+  L DNYH  +I GF+   G++IY S 
Sbjct  298  PQEPVAVISYQEVTN---VSADLFSAEDI-FYFETLRDNYHREAIIGFAWGHGEQIYAST  353

Query  358  DPVLLQENSLRQMLEDKTIKKNVFDIKRTYVGLHRLDIKAEGLDYDMLLASYLVNNENNS  417
            D  LL  +S++Q+++ K I    +D+KR+ V L +L+I   +  YD  LA+YL++  ++ 
Sbjct  354  DLSLLATDSFKQVFQ-KPI--ATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-  409

Query  418  NDLGEIAHLYDDYSVKTDLEVYGKGKKQAVPDDNDFFEHLAAKVAVIeklktplleklkD  477
            N+L+ IA+++ D S+  D  VYGKG K+AVPD + ++EHLA KV V+   K+ +L+KL  
Sbjct  410  NELSTIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTA  469

Query  478  HEQDDLYETIEIPVAFVLAKMEITGIKVEASVLNQLGNDFAVKLQELEHKIYQQAGEEFN  537
            HEQ DLY+ IE+P+A VLAKMEI GIKV+ + L++++++  V ++ L + IY+ AG+EFN
Sbjct  470  HEQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFN  529

Query  538  LNSPKQLGHILFEKLGLP--PIKKTKTGYSTSVEVLEQLKMKSPIVSEILDYRQIAKIQN  595
            +NSPKQLG ILFEK+ LP    KKTKTGYST+V+VLE+L   +PIV+ ILDYRQI+K+Q+
Sbjct  530  INSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQS  589

Query  596  TYVKGLLDCIQPDGRIHTRYLQTLTTTGRLSSVDPNLQNIPTKTEEGKQIRKAFVPSTKD  655
            TYV GL D I +DG+IHTRY+Q LT TGRLSSVDPNLQNIP + E+G+ IRKAF PS  D
Sbjct  590  TYVIGLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHED  649

Query  656  GYIFSCDYSQVELRVLAHVSGDEHMQEAFKSGYDIHAHTAMKIFHLDSPDEVTPLMRRHA  715
            + ++S DYSQ+ELRVLAH+SGDEH+  AF+ G DIH+ TAM++F +D + +VT+  RR+A
Sbjct  650  AVLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNA  709

Query  716  KAVNFGIVYGISDYGLSKNLGISRKQAKTFIENYFEQYPQIKNYMDEAIKKARENGYAET  775
            KAVNFGIVYGISD+GLS+NLGI+RKQ+K++I+ YFE+YP IK YM++ ++ A+++GY ET
Sbjct  710  KAVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVET  769

Query  776  IMHRRRYLPDIHSKNFNVRSFAERTAINSPIQGSAADIIKIAMINMQKKLDELHLKTKMV  835
            +  RRR LPDI+S+NFNVRSFAERTAINSPIQGSAADI+KIAMIN++K L+   +++KM+
Sbjct  770  LFKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKML  829

Query  836  LQVHDELIFDVPKDELDTIKKIVPEVMQSAVKLDVPLIADSNWGHNWYDAK  886
            LQVHDE++++VP+DEL +IKK+V + M++AV L VPL  D + G++WY+AK
Sbjct  830  LQVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

171) LJP_1393c in NC_017477


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  785 bits (2972),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 485/889 (55%), Positives = 681/889 (77%), Gaps = 15/889 (1%)

Query  2    AQKKLLLIDGNSVAFRAFYALYRQLDRFTSPDGLHTNAIFTFKNMLDAIMKQTNPTNVLV  61
             ++KLLLIDG+SVAFRAF+ALY Q+DRF +  GLHTNAI+ F  MLD +MK+  PT+VLV
Sbjct  3    NKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLV  62

Query  62   AFDAGKVTFRTEMYQDYKGGRQKTPSELSEQLPVIREMLKDLGIKSYELKNYEADDIIGT  121
            AFDAGK TFRTEMY DYK+GR KTP E+ EQ++ IREML  LGI  YEL +YEADDIIGT
Sbjct  63   AFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGT  122

Query  122  LSKMGE--DAGYTVDIVTGDRDLTQLASDKTTVLITKNGVGDTEAYTPDHMKEVNGVTPT  179
            L KM+E  +  + V IV+GD+DL QL+ ++T V I+K+GV++ E +TP  + E  G+TP 
Sbjct  123  LDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPN  182

Query  180  EFIDMKALMGDNSDNYPGVTKVGPKTASRLIQKYGSIEELYEHVDEMKKSKLKENLINdk  239
            +FID+KALMGD+SDN PGVTK+G KT+ +L++ +GS+E +YEH+D  K SK+KENLIND+
Sbjct  183  QFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDR  242

Query  240  dkaflakklaTIDRNSPVEVTLADTKLQEPNIEDLRNLYERLGFKKFLAELGSTGTTSSE  299
            D+AFL+K LATI+  SP+ + L D   + P++  L ++Y+ ++F ++   L+S     ++
Sbjct  243  DQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQ---MPQ  299

Query  300  QEIEKYEYLELTKENIVELDKISEKEVTFYLAMLGDNYHLAPIEGFSLKVGNKIYVSKDP  359
            + +    Y E+T+   V  D +S  ++ FY+  L DNYH  +I GF+   G++IY S D 
Sbjct  300  EPVAVISYQEVTN---VSADLFSAEDI-FYFETLRDNYHREAIIGFAWGHGEQIYASTDL  355

Query  360  VLLQENPLHKMLEDKTIKKNVFDIKRTYVGLHRLDLKAEGLDYDMLLASYLVNNENNSND  419
             LL  +++ ++++ K I    +D+KR+ V L +L++   +  YD  LA+YL++  ++ N+
Sbjct  356  SLLATDSFKQVFQ-KPI--ATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NE  411

Query  420  LGEVAHLYDDYSVKTDLEVYGKGKKQAVPNDNEFFEHLAAKVAVIeklktqlleklkDHE  479
            L+ +A+++ D S+  D  VYGKG K+AVP+ + ++EHLA KV V+   K+Q+L+KL  HE
Sbjct  412  LSTIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHE  471

Query  480  QDDLYETIEIPVAFVLAKMEITGIKVEASVLNQLGNDFAVKLQELEHKIYQQAGEEFNLN  539
            Q DLY+ IE+P+A VLAKMEI GIKV+ + L++++++  V ++ L + IY+ AG+EFN+N
Sbjct  472  QLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNIN  531

Query  540  SPKQLGHILFEKLGLP--PIKKTKTGYSTSVEVLEQLKMKSPIVSEILDYRQIAKIQNTY  597
            SPKQLG ILFEK+ LP    KKTKTGYST+V+VLE+L   +PIV+ ILDYRQI+K+Q+TY
Sbjct  532  SPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTY  591

Query  598  VKGLLDCIQPDGRIHTRYLQTLTTTGRLSSVDPNLQNIPTKTEEGKQIRKAFVPSTKDGY  657
            V GL D I +DG+IHTRY+Q LT TGRLSSVDPNLQNIP + E+G+ IRKAF PS  D+ 
Sbjct  592  VIGLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAV  651

Query  658  IFSCDYSQVELRVLAHVSGDEHMQEAFKSGYDIHAHTAMKIFHLDSPDEVTPLMRRHAKA  717
            ++S DYSQ+ELRVLAH+SGDEH+  AF+ G DIH+ TAM++F +D + +VT+  RR+AKA
Sbjct  652  LLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKA  711

Query  718  VNFGIVYGISDYGLSKNLGISRKQAKTFIENYFEQYPQIKNYMDEAIKKARENGYAETIM  777
            VNFGIVYGISD+GLS+NLGI+RKQ+K++I+ YFE+YP IK YM++ ++ A+++GY ET+ 
Sbjct  712  VNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLF  771

Query  778  HRRRYLPDIHSKNFNVRSFAERTAINSPIQGSAADIIKIAMINMQKKLDELHLKTKMVLQ  837
             RRR LPDI+S+NFNVRSFAERTAINSPIQGSAADI+KIAMIN++K L+   +++KM+LQ
Sbjct  772  KRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQ  831

Query  838  VHDELIFDVPKDELNTIKKIVPEVMQSAVKLDVPLIADSNWGHNWYDAK  886
            VHDE++++VP+DEL +IKK+V + M++AV L VPL  D + G++WY+AK
Sbjct  832  VHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

172) polA in NC_008054


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  781 bits (2955),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 471/890 (53%), Positives = 664/890 (75%), Gaps = 18/890 (2%)

Query  2    NKKLLLIDGNSVAFRAFFAMYQQLDKFKNPEGLHTNALYAFKNMLDVVLKQEDPSHILVA  61
            ++KLLLIDG+SVAFRAFFA+Y+Q+D+FKN  GLHTNA+Y+F  MLD ++K+  P+H+LVA
Sbjct  4    KNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVA  63

Query  62   FDAGKTTFRTAMYKDYKGGRDKTPAELSEQLPYLREMLKDMGIKSYELANYEADDIIGTM  121
            FDAGKTTFRT MY DYK+GR KTP E+ EQ++Y+REML  +GI  YEL +YEADDIIGT+
Sbjct  64   FDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTL  123

Query  122  AKKG--AEAGYEVAVVSGDKDLTQLASDHVTVYVTKSGVTKLEAFTPDHMKEVNGVTPTE  179
             K +  +E  ++V++VSGDKDL QL+ ++  V ++K GV+ +E FTP  + E  G+TP +
Sbjct  124  DKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQ  183

Query  180  FIDMKALMGDPSDNYPGVAKVGPKTASKLIQEYGSVENLYYHVDEMKKSKLKENLIAGKD  239
            FID+KALMGD SDN PGV+K+G KT+ KL++E+GS+E +Y H+D  K SK+KENLI ++D
Sbjct  184  FIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRD  243

Query  240  NALLGKKLATIKCDSPVEVTLDDLSYEGSNVDDLRRFYEKMNFRRFLADLAQKGELTENK  299
            +A+L+K LATI+  SP+ + LDD+ Y+G++V  L +FY+ M+F ++  +LA  +++ ++ 
Sbjct  244  QAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLA--SQMPQEP  301

Query  300  TEVKK-QDYVVLSADNLDQLPKAAEVTFYLAMFGDNYHLADFAGFALKIGGETFVSRDVF  358
              V   Q+   +SAD +     +AE  FY+  + DNYH   + GFA   G + + S D+ 
Sbjct  302  VAVISYQEVTNVSADLF-----SAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLS  356

Query  359  LLQESPLKEMLEDSAVQKNVFDLKRTTYGLYRLGIKAEGLSFDLLLASYLVDNEKNSNDL  418
            LL   ++K++++ +      +D+KR+   L +LGI   + S+D  LA+YL+    + N+L
Sbjct  357  LLATDSFKQVFQKPI---ATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTV-EDNEL  412

Query  419  GELVQGYDYYDLKTDLEVYGKGKNAKIPADDAVFFNHLAGKTAAIAALKDSLLKQLKDHE  478
            + + + +    L  D  VYGKG +  +P  D V+++HLA K   +   K  +L +L  HE
Sbjct  413  STIARIFTDISLEEDDTVYGKGAKRAVPDKD-VLLEHLARKVKVLLDSKSQMLDKLTAHE  471

Query  479  QDDLYDSIELPTARVLAKMEMNGIKVQPSRLKELENDFAVRLKELEEKIYKEAGEEFNLN  538
            Q DLY++IELP A VLAKME++GIKV+ + L+++ ++  V +  L + IY  AG+EFN+N
Sbjct  472  QLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNIN  531

Query  539  SPKQLGVILFEKLGLP--VIKKTKTGYSTSVEVLNQLKEQSPVVSDILEYRQISKIQSTY  596
            SPKQLG ILFEK+ LP  + KKTKTGYST+V+VL++L   +P+V+ IL+YRQI+K+QSTY
Sbjct  532  SPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTY  591

Query  597  VKGLLDVIDERDGRIHTRYLQTLTATGRLSSVDPNLQNIPTRTEEGKQIRKAFVPSSPDG  656
            V GL D I   DG+IHTRY+Q LT TGRLSSVDPNLQNIP R E+G+ IRKAF PS  D+
Sbjct  592  VIGLQDYILA-DGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDA  650

Query  657  YIYSCDYSQIELRVLAHVSADPNMQEAFKTGYDIHAHTAMKIFHLSSVDEVTSLQRRRAK  716
             + S DYSQIELRVLAH+S+D ++  AF+ G DIH+ TAM++F +    +VT+ +RR AK
Sbjct  651  VLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAK  710

Query  717  AVNFGIVYGISDYGLSKNLDISRKQAKEFINEYFDQYPGIQAYMDWAVKDAREKGYAETI  776
            AVNFGIVYGISD+GLS+NL+I+RKQ+K +I+ YF++YPGI+AYM+  V++A++KGY ET+
Sbjct  711  AVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETL  770

Query  777  MHRRRYLPDIHAKNFNVRSFAERTAINSPIQGSAADIMKIAMINMQKKLDELGLKTKMVV  836
              RRR LPDI+++NFNVRSFAERTAINSPIQGSAADI+KIAMIN++K L+  G+++KM++
Sbjct  771  FKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLL  830

Query  837  QVHDELIFDVPADELETIQKIVPSVMQAAVKLDVPLVADASWGHDWYEAK  886
            QVHDE++++VP DEL +I+K+V   M+AAV L VPL  D S G+ WYEAK
Sbjct  831  QVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

173) LBUL_1407 in NC_008529


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  781 bits (2955),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 471/890 (53%), Positives = 664/890 (75%), Gaps = 18/890 (2%)

Query  2    NKKLLLIDGNSVAFRAFFAMYQQLDKFKNPEGLHTNALYAFKNMLDVVLKQEDPSHILVA  61
            ++KLLLIDG+SVAFRAFFA+Y+Q+D+FKN  GLHTNA+Y+F  MLD ++K+  P+H+LVA
Sbjct  4    KNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVA  63

Query  62   FDAGKTTFRTAMYKDYKGGRDKTPAELSEQLPYLREMLKDMGIKSYELANYEADDIIGTM  121
            FDAGKTTFRT MY DYK+GR KTP E+ EQ++Y+REML  +GI  YEL +YEADDIIGT+
Sbjct  64   FDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTL  123

Query  122  AKKG--AEAGYEVAVVSGDKDLTQLASDHVTVYVTKSGVTKLEAFTPDHMKEVNGVTPTE  179
             K +  +E  ++V++VSGDKDL QL+ ++  V ++K GV+ +E FTP  + E  G+TP +
Sbjct  124  DKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQ  183

Query  180  FIDMKALMGDPSDNYPGVAKVGPKTASKLIQEYGSVENLYYHVDEMKKSKLKENLIAGKD  239
            FID+KALMGD SDN PGV+K+G KT+ KL++E+GS+E +Y H+D  K SK+KENLI ++D
Sbjct  184  FIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRD  243

Query  240  NALLGKKLATIKCDSPVEVTLDDLSYEGSNVDDLRRFYEKMNFRRFLADLAQKGELTENK  299
            +A+L+K LATI+  SP+ + LDD+ Y+G++V  L +FY+ M+F ++  +LA  +++ ++ 
Sbjct  244  QAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLA--SQMPQEP  301

Query  300  TEVKK-QDYVVLSADNLDQLPKAAEVTFYLAMFGDNYHLADFAGFALKIGGETFVSRDVF  358
              V   Q+   +SAD +     +AE  FY+  + DNYH   + GFA   G + + S D+ 
Sbjct  302  VAVISYQEVTNVSADLF-----SAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLS  356

Query  359  LLQESPLKEMLEDSAVQKNVFDLKRTTYGLYRLGIKAEGLSFDLLLASYLVDNEKNSNDL  418
            LL   ++K++++ +      +D+KR+   L +LGI   + S+D  LA+YL+    + N+L
Sbjct  357  LLATDSFKQVFQKPI---ATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTV-EDNEL  412

Query  419  GELVQGYDYYDLKTDLEVYGKGKNAKIPADDAVFFNHLAGKTAAIAALKDSLLKQLKDHE  478
            + + + +    L  D  VYGKG +  +P  D V+++HLA K   +   K  +L +L  HE
Sbjct  413  STIARIFTDISLEEDDTVYGKGAKRAVPDKD-VLLEHLARKVKVLLDSKSQMLDKLTAHE  471

Query  479  QDDLYDSIELPTARVLAKMEMNGIKVQPSRLKELENDFAVRLKELEEKIYKEAGEEFNLN  538
            Q DLY++IELP A VLAKME++GIKV+ + L+++ ++  V +  L + IY  AG+EFN+N
Sbjct  472  QLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNIN  531

Query  539  SPKQLGVILFEKLGLP--VIKKTKTGYSTSVEVLNQLKEQSPVVSDILEYRQISKIQSTY  596
            SPKQLG ILFEK+ LP  + KKTKTGYST+V+VL++L   +P+V+ IL+YRQI+K+QSTY
Sbjct  532  SPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTY  591

Query  597  VKGLLDVIDERDGRIHTRYLQTLTATGRLSSVDPNLQNIPTRTEEGKQIRKAFVPSSPDG  656
            V GL D I   DG+IHTRY+Q LT TGRLSSVDPNLQNIP R E+G+ IRKAF PS  D+
Sbjct  592  VIGLQDYILA-DGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDA  650

Query  657  YIYSCDYSQIELRVLAHVSADPNMQEAFKTGYDIHAHTAMKIFHLSSVDEVTSLQRRRAK  716
             + S DYSQIELRVLAH+S+D ++  AF+ G DIH+ TAM++F +    +VT+ +RR AK
Sbjct  651  VLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAK  710

Query  717  AVNFGIVYGISDYGLSKNLDISRKQAKEFINEYFDQYPGIQAYMDWAVKDAREKGYAETI  776
            AVNFGIVYGISD+GLS+NL+I+RKQ+K +I+ YF++YPGI+AYM+  V++A++KGY ET+
Sbjct  711  AVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETL  770

Query  777  MHRRRYLPDIHAKNFNVRSFAERTAINSPIQGSAADIMKIAMINMQKKLDELGLKTKMVV  836
              RRR LPDI+++NFNVRSFAERTAINSPIQGSAADI+KIAMIN++K L+  G+++KM++
Sbjct  771  FKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLL  830

Query  837  QVHDELIFDVPADELETIQKIVPSVMQAAVKLDVPLVADASWGHDWYEAK  886
            QVHDE++++VP DEL +I+K+V   M+AAV L VPL  D S G+ WYEAK
Sbjct  831  QVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

174) WANG_0240 in NC_015602


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  779 bits (2949),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 484/894 (55%), Positives = 684/894 (77%), Gaps = 21/894 (2%)

Query  1    MADK-KLLLIDGNSVAFRAFYALYRQLESFKNPEGLHTNAIYAFKNMLDVLLKDVEPTNV  59
            M +K KLLLIDG+SVAFRAF+ALY Q++ FKN  GLHTNAIY+F  MLD ++K V PT+V
Sbjct  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60

Query  60   LVAFDAGKVTFRTKMYSDYKGGRAKTPEELLEQMPYIQELLHDLGIKTYELKDYEADDII  119
            LVAFDAGK TFRT MY+DYK+GRAKTP+E+ EQ +YI+E+L  LGI  YEL +YEADDII
Sbjct  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120

Query  120  GTFVQKGE--DAGFTTTVVTGDRDLTQLASDKTTVEVTKSGVSQLEAYTPEHMKEVNGVT  177
            GT+ + +E  +  F  T+V+GD+DL QL+ ++T VE++K GV+++E +TP  + E  G+T
Sbjct  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180

Query  178  PTEFIDMKALMGDNSDNYPGVTKVGPKTASRLIQKYGSVEDLYEHVDEMKKSKLKENLIN  237
            P +FID+KALMGD+SDN PGVTK+G KT+ +L++ +GS+E++YEH+D  K SK+KENLIN
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  238  dkdkaflakklaTIDRDSPVTIGIDDVKREPVDYEKLRQFYEQMNFRKFLADLNASGKGQ  297
            D+D+AFL+K LATI+  SP+TIG+DD+  +  D   L QFY++M+F ++  +L AS   Q
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGL-ASQMPQ  299

Query  298  AATEVEKVEYTVLNDQNVKDIKAS--ENDQVEFYLAMLGANYHLADFVGFSLKINDQIYV  355
             +  V  + Y     Q+V ++ A     +++ FY+  L  NYH   ++GF+    +QIY 
Sbjct  300  EPVAV--ISY-----QEVTNVSADLFSAEDI-FYFETLRDNYHREAIIGFAWGHGEQIYA  351

Query  356  SRDVDLLSEDNLKHLLEDEKIKKNVFDLKRTTVGLNRLGIHAHGLDYDMLLASYLVNNEN  415
            S D+ LL+ D++K++++        +D+KR+ V L++LGI+  +  YD  LA+YL++  +
Sbjct  352  STDLSLLATDSFKQVFQKPI---ATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVE  408

Query  416  NSNDLGEIAHLYGDYSVKTDIEVYGKGKSEHVPDEDDDLFNHLASKVNVIAklkepllqk  475
            + N+L+ IA+++ D S+  D  VYGKG    VPD  D L++HLA KV+V+   K  +L+K
Sbjct  409  D-NELSTIARIFTDISLEEDDTVYGKGAKRAVPD-KDVLLEHLARKVKVLLDSKSQMLDK  466

Query  476  lkeheQDDLFDTIEIPTARVLAKMEMNGMKVEASTLIQLQNEFAVKLKELEDKIYQQAGE  535
            L  HEQ DL++ IE+P A VLAKME++G+KV+ +TL ++ ++  V +  L + IY+ AG+
Sbjct  467  LTAHEQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQ  526

Query  536  RFNLNSPKQLGHILFEKLNLP--VLKKTKTGYSTSVEVLDQLKTQSPIVSEILDYRQIAK  593
             FN+NSPKQLG ILFEK++LP  + KKTKTGYST+V+VL++L   +PIV+ ILDYRQI+K
Sbjct  527  EFNINSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITK  586

Query  594  IQSTYVKGLLDVIQPDGRVHTRYLQTLTATGRLSSVDPNLQNIPTRTEEGKQIRKAFVPT  653
            +QSTYV GL D I +DG++HTRY+Q LT TGRLSSVDPNLQNIP R E+G+ IRKAF P+
Sbjct  587  LQSTYVIGLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPS  646

Query  654  DPDGYIFSCDYSQVELRVLAHVSGDAHMQEAFKTGYDIHSHTAMKIFHLDSPDEVTPLMR  713
            + D+ ++S DYSQ+ELRVLAH+SGD H+  AF+ G DIH+ TAM++F +D + +VT+  R
Sbjct  647  HEDAVLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDR  706

Query  714  RHAKAVNFGIVYGISDYGLSKNLGISRKQAKEFINNYFEQYPQIKDYMDKAVQEARDKGY  773
            R+AKAVNFGIVYGISD+GLS+NLGI+RKQ+K +I+ YFE+YP IK YM++ V+EA+DKGY
Sbjct  707  RNAKAVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGY  766

Query  774  AETIMHRRRYLPDIHAKKYTVRAFAERTAINSPIQGSAADIIKIAMINMQKKLDELHLKT  833
             ET+  RRR LPDI+++++ VR+FAERTAINSPIQGSAADI+KIAMIN++K L+   +++
Sbjct  767  VETLFKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRA  826

Query  834  KMVVQVHDELIFDVPKDELETIKKIVPEVMQSAVKLDVPLIADSGWGHNWYDAK  887
            KM++QVHDE++++VP+DEL +IKK+V + M++AV L VPL  D + G++WY+AK
Sbjct  827  KMLLQVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

175) LGAS_1421 in NC_008530


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  777 bits (2939),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 481/889 (55%), Positives = 680/889 (77%), Gaps = 15/889 (1%)

Query  12   AQKKLLLIDGNSVAFRAFYALYRQLDRFTSPDGLHTNAIFTFKNMLDAIMKQTDPSNVLV  71
             ++KLLLIDG+SVAFRAF+ALY Q+DRF +  GLHTNAI+ F  MLD +MK+  P++VLV
Sbjct  3    NKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLV  62

Query  72   AFDAGKVTFRTKMYQDYKGGRQKTPSELSEQLPVIREMLKDLGIKSYELKNYEADDIIGT  131
            AFDAGK TFRT MY DYK+GR KTP E+ EQ++ IREML  LGI  YEL +YEADDIIGT
Sbjct  63   AFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGT  122

Query  132  LSKMGE--EAGYTVDIVTGDRDLTQLASDKTTVLITKNGVGDTEAYTPEHMKEVNGVTPT  189
            L KM+E  E  + V IV+GD+DL QL+ ++T V I+K+GV++ E +TP  + E  G+TP 
Sbjct  123  LDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPN  182

Query  190  EFIDMKALMGDNSDNYPGVTKVGPKTASRLIQKYGSVEKLYEHVDEMKKSKLKENLINdk  249
            +FID+KALMGD+SDN PGVTK+G KT+ +L++ +GS+E +YEH+D  K SK+KENLIND+
Sbjct  183  QFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDR  242

Query  250  dkailakklatidRDSPVEVTLADTKLEEPNIEDLRNLYERLGFKKFLAELGASGVSAGK  309
            D+A+L+K LATI+  SP+ + L D   + P++  L ++Y+ ++F ++   L++      +
Sbjct  243  DQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQ---MPQ  299

Query  310  QESEKYEYLELTRENIADLDKINEKEVTFYLAMLGDNYHLAPLEGFSLKVSDKIYVSKDV  369
            +      Y E+T  + ADL  ++  ++ FY+  L DNYH  ++ GF+   +++IY S D+
Sbjct  300  EPVAVISYQEVTNVS-ADL--FSAEDI-FYFETLRDNYHREAIIGFAWGHGEQIYASTDL  355

Query  370  VLLQEAPLRQMLEDKKIKKNVFDIKRTYVGLHRLDIDAEGLDYDMLLASYLVNNENNSND  429
             LL   +++Q+++ K I    +D+KR+ V L +L+I+  +  YD  LA+YL++  ++ N+
Sbjct  356  SLLATDSFKQVFQ-KPI--ATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NE  411

Query  430  LGEVAHLYDDYSVKTDLEVYGKGKKQAVPEDDEFFEHLAAKVAVIeklkqplleklkDHE  489
            L+ +A+++ D S+  D  VYGKG K+AVP+ D ++EHLA KV V+   K  +L+KL  HE
Sbjct  412  LSTIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHE  471

Query  490  QDDLYETIEIPVAFVLAKMEITGIKVEASVLNQLGNDFAVKLQELEHKIYQQAGEEFNLN  549
            Q DLY+ IE+P+A VLAKMEI GIKV+ + L++++++  V ++ L + IY+ AG+EFN+N
Sbjct  472  QLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNIN  531

Query  550  SPKQLGHILFEKLNLP--PIKKTKTGYSTSVEVLEQLKMKSPIVSEILDYRQIAKIQNTY  607
            SPKQLG ILFEK++LP    KKTKTGYST+V+VLE+L   +PIV+ ILDYRQI+K+Q+TY
Sbjct  532  SPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTY  591

Query  608  VKGLLECIQPDSRIHTRYLQTLTATGRLSSVDPNLQNIPTRTDEGKQIRKAFVPSTKDGY  667
            V GL + I +D++IHTRY+Q LT TGRLSSVDPNLQNIP R ++G+ IRKAF PS  D+ 
Sbjct  592  VIGLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAV  651

Query  668  IFSCDYSQVELRVLAHVSGDEHMQEAFKSGYDIHAHTAMKIFHLDSPDEVTPLMRRHAKA  727
            ++S DYSQ+ELRVLAH+SGDEH+  AF+ G DIH+ TAM++F +D + +VT+  RR+AKA
Sbjct  652  LLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKA  711

Query  728  VNFGIVYGISDYGLSKNLGISRKQAKTFIDNYFEQYPQIKDYMDKAIKKARENGYAETIM  787
            VNFGIVYGISD+GLS+NLGI+RKQ+K++ID YFE+YP IK YM++ ++ A+++GY ET+ 
Sbjct  712  VNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLF  771

Query  788  HRRRYLPDIHSKNFNVRSFAERTAINSPIQGSAADIIKIAMINMQKKLDELHLKTKMVLQ  847
             RRR LPDI+S+NFNVRSFAERTAINSPIQGSAADI+KIAMIN++K L+   +++KM+LQ
Sbjct  772  KRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQ  831

Query  848  VHDELIFDVPKDELDTIKKIVPEVMQSAVKLDVPLIADSNWGHNWYDAK  896
            VHDE++++VP+DEL +IKK+V + M++AV L VPL  D + G++WY+AK
Sbjct  832  VHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

176) polA in NC_021744


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  774 bits (2930),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 480/890 (54%), Positives = 676/890 (76%), Gaps = 20/890 (2%)

Query  4    KKLLLIDGNSVAFRAFYALYRQLESFKSPDGLHTNAIYAFKNMLDVLLKDVDPTHVLVAF  63
            +KLLLIDG+SVAFRAF+ALY Q++ FK+  GLHTNAIY+F  MLD ++K V PTHVLVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  64   DAGKVTFRTKMYVEYKGGRAKTPEELLEQMPYIQEMLHDLGIKTYELKNYEADDIIGTFA  123
            DAGK TFRT MY +YK+GRAKTP+E+ EQ +YI+EML  LGI  YEL +YEADDIIGT+ 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  124  AKGEK--VGFTTTIVTGDRDLTQLASPSTTVEVTKSGVSQLEAYTPEHMKEVNGVTPTEF  181
              +E+  V F  TIV+GD+DL QL+  +T VE++K GV+++E +TP  + E  G+TP +F
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  182  IDMKALMGDNSDNYPGVTKVGPKTASRLIQKYGSVEGIYDHIDEMKKSKLKENLINdkdk  241
            ID+KALMGD+SDN PGVTK+G KT+ +L++ +GS+EGIY+HID  K SK+KENLIND+D+
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRDQ  244

Query  242  aflakklaTIDRDSPVTLDIDDIKRQPVDYEKLRQFYEKMNFRKFLADLNASGAGQDSTE  301
            AFL+K LATI+  SP+T+++DDI  +  D   L QFY+ M+F ++  +L AS   Q++  
Sbjct  245  AFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGL-ASQMPQEPVA  303

Query  302  VEKVEYIVLNDDNVKDVKAT--EADTIEFYLEMLGANYHLAPFVGFSLKINDKIYVSRDV  359
            V  + Y     ++V +V A    A+ I FY+E L  NYH  +++GF+    ++IY S D+
Sbjct  304  V--ISY-----QEVTNVSADLFSAEDI-FYFETLRDNYHREAIIGFAWGHGEQIYASTDL  355

Query  360  ELLEEDNIKHILEDEKIKKNVFDLKRTMVAAHRLGIHTHGLDYDMLLASYLINNENNSND  419
             LL  D++K++++        +D+KR+ V   +LGI+  +  YD  LA+YL++  ++ N+
Sbjct  356  SLLATDSFKQVFQKPI---ATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NE  411

Query  420  LGEIAHLYGDYSVKTDLEVYGKGKSEHIPDDDDELFNHLASKVNAIESlkktlleklkDH  479
            L+ IA+++ D S+  D  VYGKG    +PD D  L++HLA KV+ +   K  +L+KL  H
Sbjct  412  LSTIARIFTDISLEEDDTVYGKGAKRAVPDKD-VLLEHLARKVKVLLDSKSQMLDKLTAH  470

Query  480  EQDALFDTIEIPTARVLARMEMNGMKVEASTLIQLQNEFAVKLKELEDKIYGQAGEKFNL  539
            EQ  L++ IE+P A VLA+ME++G+KV+ +TL ++ ++  V +  L + IY+ AG+ FN+
Sbjct  471  EQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNI  530

Query  540  NSPKQLGHILFEKLGLPV--IKKTKTGYSTAVEVLDQLKTQSPIVSEILDYRQIAKIQST  597
            NSPKQLG ILFEK+ LP+   KKTKTGYSTAV+VL++L   +PIV+ ILDYRQI+K+QST
Sbjct  531  NSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQST  590

Query  598  YVKGLLDVIQPDGRVHTRYLQTLTATGRLSSVDPNLQNIPTRTEEGKQIRKAFVPSEPDG  657
            YV GL D I +DG++HTRY+Q LT TGRLSSVDPNLQNIP R E+G+ IRKAF PS+ D+
Sbjct  591  YVIGLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDA  650

Query  658  YIFSCDYSQVELRVLAHVSGDQNMQEAFKTGYDIHSHTAMKIFHLESPDEVTPLMRRHAK  717
             ++S DYSQ+ELRVLAH+SGD+++  AF+ G DIH+ TAM++F ++ + +VT+  RR+AK
Sbjct  651  VLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAK  710

Query  718  AVNFGIVYGISDYGLSKNLGISRKRAQEFIDNYFEQYPQIEDYMNKAVQEARDKGYAETI  777
            AVNFGIVYGISD+GLS+NLGI+RK+++ +ID YFE+YP I  YM++ V+EA+DKGY ET+
Sbjct  711  AVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETL  770

Query  778  MHRRRYLPDIHAKKYTVRAFAERTAINSPIQGSAADIIKIAMINMQKKLDELHLKTKMVI  837
              RRR LPDI+++++ VR+FAERTAINSPIQGSAADI+KIAMIN++K L+   +++KM++
Sbjct  771  FKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLL  830

Query  838  QVHDELIFDVPKDELETIKKIVPEVMQSAVKLDVPLIADSGWGHNWYDAK  887
            QVHDE++++VP+DEL +IKK+V + M++AV L VPL  D + G++WY+AK
Sbjct  831  QVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

177) Lbuc_1217 in NC_015428


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  774 bits (2931),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 468/887 (53%), Positives = 676/887 (77%), Gaps = 16/887 (1%)

Query  3    KKLLLIDGNSIAFKAFYALYTAMDKFTNPSGLHTSAIYGFNRMLDKVLADEKPTDVLVAF  62
            +KLLLIDG+S+AF+AF+ALY  +D+F N SGLHT+AIYGF+ MLD ++   +PT+VLVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  63   DAGKTTFRTKMYADYKGGRAKTPTELSEQFPFLKELINARGISTYELPDYEADDIIGTLA  122
            DAGKTTFRT MYADYK+GRAKTP E+ EQF++++E++ A GI+ YEL +YEADDIIGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  123  KKAEEAG-DYQVVIVTGDRDLTQLTSDKTTVQVSKKGVTELETYTPKHVEEKLGVKPSQI  181
            K AE +   ++V IV+GD+DL QLT ++T V++SKKGV+E+E +TP  + EK+G+ P+Q+
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  182  IEIKGLKGDNSDNYPGVEKVGDKTAVKLVQQFGTIDNLYQNIDQVSGKKLKEHLIHDQAQ  241
            I++K+L GD+SDN PGV K+G+KT++KL+++FG+++ +Y++ID     K+KE+LI+D+ Q
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRDQ  244

Query  242  AERAHTLATINRDAPVTVSLDQLKYQGDNIDKLTDFYERMGFKSFLAKLSVddqdhaddq  301
            A  + TLATIN  +P+T++LD++ Y+G ++  L++FY+ M+F  +  K ++  Q   +  
Sbjct  245  AFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQL--KKGLASQMPQEPV  302

Query  302  adIQYTVLSAKNAAELDQFTDEVTFHLEMSEENYHTSPLVGFAIGQGNKWYVTNDPELLH  361
            A I Y  ++  +A   D F+ E  F +E   +NYH  +++GFA G+G++ Y + D  LL 
Sbjct  303  AVISYQEVTNVSA---DLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLA  359

Query  362  NQHVSDLLTSKTIKKNLFDAKRTYVGLYRQGIELANVDFDMLLVSYLLNTTNNSNDVGTV  421
             +   +++  K I    +D KR+ V L + GIEL    +D  L +YLL+T ++ N+++T+
Sbjct  360  TDSFKQVF-QKPIAT--YDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NELSTI  415

Query  422  AHLHGFYNVKTDEEVYGKGAKRHIDPQSPAFLAHLVHKVKAIDALHDGMFKDLDAHNQSK  481
            A++    ++  D+ VYGKGAKR + P+   +L HL +KVK +      M+  L AH+Q  
Sbjct  416  ARIFTDISLEEDDTVYGKGAKRAV-PDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLD  474

Query  482  LYWDIEIKIAFVLAHMEINGIKVDAATLEGMGSKFKERLAEIEQTIFQEAGEEFNIGSPK  541
            LY +IE+ +A VLA MEI+GIKV+ ATL++M+ + K  +  + Q I++ AG+EFNI SPK
Sbjct  475  LYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPK  534

Query  542  QLGKILFEKLRLPI--LKKTKTGYSTSVDVLEKLAPDAPIVQNVLDYRQISKLQSTYVDG  599
            QLG ILFEK++LP+   KKTKTGYST+VDVLE+LAP APIV ++LDYRQI+KLQSTYV G
Sbjct  535  QLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIG  594

Query  600  LLKVIHPDDSKVHTRYLQTLTQTGRLSSVDPNLQNIPVRSEEGRLIRQAFIPSHPGWQIF  659
            L   I +D +K+HTRY+Q LTQTGRLSSVDPNLQNIP+R E+GRLIR+AF PSH +  ++
Sbjct  595  LQDYILAD-GKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLL  653

Query  660  SSDYSQIELRVLASITDDQNMQDAFKNGEDIHATTARRIFGLPSNEEVTPELRRQAKAVN  719
            SSDYSQIELRVLA I++D+++  AF++G DIH++TA R+FG+    +VT++ RR+AKAVN
Sbjct  654  SSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVN  713

Query  720  FGIVYGISDFGLASNTGITRKQAHQFIERYFEEYPGVKKYTEDIVEFARNHRYVETIAHR  779
            FGIVYGISDFGL++N GITRKQ+  +I+ YFE YPG+K Y E++V  A++  YVET+  R
Sbjct  714  FGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKR  773

Query  780  RRYLPDINSKSFNLRSFAERTAMNTPIQGSAADIIKIAMINMADAIK--DMKTRMLLQVH  837
            RR LPDINS++FN+RSFAERTA+N+PIQGSAADI+KIAMIN+  A++  + +++MLLQVH
Sbjct  774  RRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVH  833

Query  838  DELIFEVPDEELDTVKQLIPSVMDSAIHLNVPLKVESHWGKTWYDAK  884
            DE+++EVP++EL ++K+L+   M++A++L VPL V+   G++WY+AK
Sbjct  834  DEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

178) polA in NC_018610


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  774 bits (2930),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 467/887 (53%), Positives = 676/887 (77%), Gaps = 16/887 (1%)

Query  3    KKLLLIDGNSIAFKAFYALYTAMDKFTNPSGLHTSAIYGFNRMLDKVLADEKPTDVLVAF  62
            +KLLLIDG+S+AF+AF+ALY  +D+F N SGLHT+AIYGF+ MLD ++   +PT+VLVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  63   DAGKTTFRTKMYADYKGGRAKTPTELSEQFPFLKELINARGISTYELPDYEADDIIGTLA  122
            DAGKTTFRT MYADYK+GRAKTP E+ EQF++++E++ A GI+ YEL +YEADDIIGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  123  KKAEEAG-DYQVVIVTGDRDLTQLTSDKTTVQVSKKGVTELETYTPKHVEEKLGVKPSQI  181
            K AE +   ++V IV+GD+DL QLT ++T V++SKKGV+E+E +TP  + EK+G+ P+Q+
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  182  IEIKGLKGDNSDNYPGVEKVGDKTAVRLVQQFGTIDNLYQNIDQVSGKKLKEHLIHDQAQ  241
            I++K+L GD+SDN PGV K+G+KT+++L+++FG+++ +Y++ID     K+KE+LI+D+ Q
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRDQ  244

Query  242  AERAHTLATINRDAPVTVSLDQLKYQGDNIDKLTDFYERMGFKSFLAKLSVddqdhaddq  301
            A  + TLATIN  +P+T++LD++ Y+G ++  L++FY+ M+F  +  K ++  Q   +  
Sbjct  245  AFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQL--KKGLASQMPQEPV  302

Query  302  adIQYTVLSAKNAAELDQFTDEVTFHLEMSEENYHTSPLVGFAIGQGDKWYVTNDPELLH  361
            A I Y  ++  +A   D F+ E  F +E   +NYH  +++GFA G+G++ Y + D  LL 
Sbjct  303  AVISYQEVTNVSA---DLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLA  359

Query  362  NQHVIDLLTSKTIKKNVFDAKRTYVGLYRQGIELANVDFDMLLVSYLLNTTNNSNDVGTV  421
             +   +++  K I    +D KR+ V L + GIEL    +D  L +YLL+T ++ N+++T+
Sbjct  360  TDSFKQVF-QKPI--ATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NELSTI  415

Query  422  AHLHGFYNVKTDEEVYGKGAKRHIDPQSPAFLAHLVHKVKAIDALHDGMFKDLDAHNQSK  481
            A++    ++  D+ VYGKGAKR + P+   +L HL +KVK +      M+  L AH+Q  
Sbjct  416  ARIFTDISLEEDDTVYGKGAKRAV-PDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLD  474

Query  482  LYWDIEIKIAFVLAHMEINGIKVDAATLEGMGSKFKERLAEIEQTIFQEAGEEFNIGSPK  541
            LY +IE+ +A VLA MEI+GIKV+ ATL++M+ + K  +  + Q I++ AG+EFNI SPK
Sbjct  475  LYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPK  534

Query  542  QLGKILFEKLRLPI--LKKTKTGYSTSVDVLEKLAPDAPIVQNVLDYRQISKLQSTYVDG  599
            QLG ILFEK++LP+   KKTKTGYST+VDVLE+LAP APIV ++LDYRQI+KLQSTYV G
Sbjct  535  QLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIG  594

Query  600  LLKVIHPDDSKVHTRYLQTLTQTGRLSSVDPNLQNIPVRSEEGRLIRQAFIPSHPGWQIF  659
            L   I +D +K+HTRY+Q LTQTGRLSSVDPNLQNIP+R E+GRLIR+AF PSH +  ++
Sbjct  595  LQDYILAD-GKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLL  653

Query  660  SSDYSQIELRVLASITDDQNMQDAFKNGEDIHATTARRIFGLPSNEEVTPELRRQAKAVN  719
            SSDYSQIELRVLA I++D+++  AF++G DIH++TA R+FG+    +VT++ RR+AKAVN
Sbjct  654  SSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVN  713

Query  720  FGIVYGISDFGLASNTGITRKQAHQFIERYFEEYPGVKKYTEDIVEFARNHRYVETIAHR  779
            FGIVYGISDFGL++N GITRKQ+  +I+ YFE YPG+K Y E++V  A++  YVET+  R
Sbjct  714  FGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKR  773

Query  780  RRYLPDINSKSFNLRSFAERTAMNTPIQGSAADIIKIAMINMADAIK--DMKTRMLLQVH  837
            RR LPDINS++FN+RSFAERTA+N+PIQGSAADI+KIAMIN+  A++  + +++MLLQVH
Sbjct  774  RRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVH  833

Query  838  DELIFEVPDEELDTVKQLIPSVMDSAIHLNVPLKVESHWGKTWYDAK  884
            DE+++EVP++EL ++K+L+   M++A++L VPL V+   G++WY+AK
Sbjct  834  DEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

179) LAB52_07810 in NC_017470


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  772 bits (2923),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 479/887 (55%), Positives = 677/887 (77%), Gaps = 15/887 (1%)

Query  4    KKLLLIDGNSVAFRAFYALYRQLESFKSPDGLHTNAIYAFKNMLDVLLKDVDPTHVLVAF  63
            +KLLLIDG+SVAFRAF+ALY Q++ FK+  GLHTNAIY+F  MLD ++K V PTHVLVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  64   DAGKVTFRTKMYGEYKGGRAKTPEELLEQMPYIQEMLHDLGIKTYELKNYEADDIIGTFA  123
            DAGK TFRT MY++YK+GRAKTP+E+ EQ +YI+EML  LGI  YEL +YEADDIIGT+ 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  124  AKGEKTG--FTTTIVTGDRDLTQLASDKTTVEVTKSGVSQLEAYTPEHMKEVNGVTPTEF  181
              +E+T   F  TIV+GD+DL QL+ ++T VE++K GV+++E +TP  + E  G+TP +F
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  182  IDMKALMGDSSDNYPGVTKVGPKTASRLIQKYGSVEGIYDHIDEMKKSKLKENLINdkdk  241
            ID+KALMGD SDN PGVTK+G KT+ +L++ +GS+EGIY+HID  K SK+KENLIND+D+
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRDQ  244

Query  242  aflakklaTIDRDSPVTLDIDDIKRQPVDYEKLRQFYEKMNFRKFLADLNASGAGQDSTE  301
            AFL+K LATI+  SP+T+++DDI  +  D   L QFY+ M+F ++  +L AS   Q++  
Sbjct  245  AFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGL-ASQMPQEPVA  303

Query  302  VEKVEYIVLNDNVKDVKATEDDTIEFYLEMLGANYHLAPFVGFSLKINDKIYVSRDVELL  361
            V  + Y  + +   D+ ++ED    FY+E L  NYH  +++GF+    ++IY S D+ LL
Sbjct  304  V--ISYQEVTNVSADLFSAED---IFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLL  358

Query  362  EEDNIKHILEDEKIKKNVFDLKRTMVAAHRLGIHTHGLDYDMLLASYLINNENNSNDLGE  421
              D++K++++        +D+KR+ V   +LGI+  +  YD  LA+YL++  ++ N+L+ 
Sbjct  359  ATDSFKQVFQKPI---ATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NELST  414

Query  422  IAHLYGDYSVKTDLEVYGKGKSEHIPDDDDELFNHLASKVNAIeklkrellkklkeheQD  481
            IA+++ D S+  D  VYGKG    +PD D  L++HLA KV+ +   K ++L KL  HEQ 
Sbjct  415  IARIFTDISLEEDDTVYGKGAKRAVPDKD-VLLEHLARKVKVLLDSKSQMLDKLTAHEQL  473

Query  482  ALFDTIEIPTACVLARMEMNGMKVEASTLIQLQNEFAVKLKELEDKIYGQAGEKFNLNSP  541
             L++ IE+P A VLA+ME++G+KV+ +TL ++ ++  V +  L + IY+ AG+ FN+NSP
Sbjct  474  DLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSP  533

Query  542  KQLGHILFEKLGLPV--IKKTKTGYSTSVEVLDQLKTQSPIVSEILDYRQIAKIQSTYVK  599
            KQLG ILFEK+ LP+   KKTKTGYST+V+VL++L   +PIV+ ILDYRQI+K+QSTYV 
Sbjct  534  KQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVI  593

Query  600  GLLDVIQPDGRVHTRYLQTLTATGRLSSVDPNLQNIPTRTEEGKQIRKAFVPSEPDGYIF  659
            GL D I +DG++HTRY+Q LT TGRLSSVDPNLQNIP R E+G+ IRKAF PS+ D+ ++
Sbjct  594  GLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLL  653

Query  660  SCDYSQVELRVLAHVSGDQNMQEAFKTGYDIHSHTAMKIFHLDSPDQVTPLMRRHAKAVN  719
            S DYSQ+ELRVLAH+SGD+++  AF+ G DIH+ TAM++F +D + +VT+  RR+AKAVN
Sbjct  654  SSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVN  713

Query  720  FGIVYGISDYGLSKNLGISRKRAQEFIDNYFEQYPQIKDYMDKAVQEARDKGYAETIMHR  779
            FGIVYGISD+GLS+NLGI+RK+++ +ID YFE+YP IK YM++ V+EA+DKGY ET+  R
Sbjct  714  FGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKR  773

Query  780  RRYLPDIHAKKYTVRAFAERTAINSPIQGSAADIIKIAMINMQKKLDELHLKTKMVVQVH  839
            RR LPDI+++++ VR+FAERTAINSPIQGSAADI+KIAMIN++K L+   +++KM++QVH
Sbjct  774  RRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVH  833

Query  840  DELIFDVPKDELETIKKIVPEVMQSAVKLDVPLIADSGWGHNWYDAK  886
            DE++++VP+DEL +IKK+V + M++AV L VPL  D + G++WY+AK
Sbjct  834  DEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

180) LBFF_1431 in NC_021235


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  770 bits (2915),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 472/887 (54%), Positives = 667/887 (76%), Gaps = 15/887 (1%)

Query  33   KQLLLIDGNSIVFRAFFAMHNQMEKFTNQAGLHTAAIYGFKLMLDHILKEVQPDAALVAF  92
            ++LLLIDG+S+ FRAFFA+ NQ+++F N++GLHT AIYGF LMLDH++K V+P   LVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  93   DAGKTTFRTEKYADYKGSRDKTPGELVEQLPYVRKLVEASGLHAYELVNYEADDIIGTLA  152
            DAGKTTFRTE YADYK++R KTP+E+ EQ++Y+R ++ A G+  YEL +YEADDIIGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  153  KEGDQAG--FETMIVTGDRDLTQLATDHTTVAVTKRGVTQTEEFTPAYMQEKLGVTPRQY  210
            K ++++   F+  IV+GD+DL QL+ ++T V ++K+GV++ EEFTPAY+ EK+G+TP Q+
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  211  IDVKALMGDSSDNYPGVTKIGEKTAVSLIQEYGSLDGLYENIAAMKKSKRKENLINEEKI  270
            ID+KALMGD SDN PGVTKIGEKT++ L++E+GSL+G+YE+I + K SK KENLIN+   
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRDQ  244

Query  271  ARECQDLATIHRDAPLAIGLKDIAYQGPDEAALIDLYQELDFKSFLKELGAQEGGAQVDQ  330
            A   + LATI+  +P++IGL DI Y+GPD A+L ++Y+E+DF  + K L++Q     V  
Sbjct  245  AFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEPV--  302

Query  331  APIEYQVLDEDNMALVDQLGATVCFQLEMPDANYHESPLAGFVVGDGKRWLVSRNADLLT  390
            A I YQ + + +  L   ++A   F +E    NYH  ++ GF  G+G +   S +  LL+
Sbjct  303  AVISYQEVTNVSADL---FSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLA  359

Query  391  TAPLKKLLEDPAVEKDVFNAKAQLVGLHRLGVDLAGVDFDLLLASYLLNTSENANDLGVL  450
            T ++K++++ P      ++ K   V L +LG++L +  +D  LA+YLL+T E+ N+L+ +
Sbjct  360  TDSFKQVFQKPI---ATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NELSTI  415

Query  451  AAAHDYHQVQTDEEVYGKGAKRAIPADDEVFFTHLAKKARAIRDLKEPLYQQLTDNEQLP  510
            A       ++ D+ VYGKGAKRA+P D +V++ HLA+K + + D K  + ++LT +EQL 
Sbjct  416  ARIFTDISLEEDDTVYGKGAKRAVP-DKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLD  474

Query  511  LYEDIERPLSAVLAHMEITGIHVDAATLKEMGSKLVEREAELEQAIYQEAGEEFNINSPK  570
            LY++IE PL+ VLA MEI GI V+ ATL++M+ +       L Q IY+ AG+EFNINSPK
Sbjct  475  LYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPK  534

Query  571  QLGVILFEKMKLP--VIKKTKTGYSTAVDVLEKLADRAPIVQDILAYRQISKLQSTYITG  628
            QLG ILFEKM+LP  + KKTKTGYSTAVDVLE+LA  APIV  IL YRQI+KLQSTY+ G
Sbjct  535  QLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIG  594

Query  629  LLKVIHQDDQKIHTRYLQTLTATGRLSSVDPNLQNIPVRLEEGRQIRRAFTPSAPGWKIF  688
            L   I  D+ KIHTRY+Q LT TGRLSSVDPNLQNIP+RLE+GR IR+AFTPS  +  ++
Sbjct  595  LQDYILADG-KIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLL  653

Query  689  SSDYSQVELRVLAHVTGDKNMQADFLAGKDIHAATAKRIFHLQSEDEVTPNMRRQAKAVN  748
            SSDYSQ+ELRVLAH++GD ++ A F  G DIH++TA R+F ++   +VT+N RR+AKAVN
Sbjct  654  SSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVN  713

Query  749  FGIVYGISDYGLAQNIHVSRPQAHEFIQSYFKEFPGVEKYVHDIVELAKQQGYVETLTHR  808
            FGIVYGISD+GL++N+ ++R Q+  +I++YF  +PG+  Y++++V  AK++GYVETL  R
Sbjct  714  FGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKR  773

Query  809  RRYLPEIHAKSFTQRSFAERMAMNTPIQGSAADIIKIAMIRMEKALKERGLRARMLLQIH  868
            RR LP+I++++F  RSFAER A+N+PIQGSAADI+KIAMI ++KAL+  G+RA+MLLQ+H
Sbjct  774  RRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVH  833

Query  869  DELVFeapeeeiatleelVPSIMDSAVKLDVPLKVESKSGATWYDLK  915
            DE+V+E P++E++++  LV   M++AV L VPL V+  +G +WY+ K
Sbjct  834  DEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

181) LBHH_0560 in NC_017467


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  769 bits (2912),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 481/890 (55%), Positives = 670/890 (76%), Gaps = 20/890 (2%)

Query  4    KKLLLIDGNSVAFRAFYALYRQLESFKSPDGLHTNAIYAFKNMLDVLLKDVDPTHVLVAF  63
            +KLLLIDG+SVAFRAF+ALY Q++ FK+  GLHTNAIY+F  MLD ++K V PTHVLVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  64   DAGKVTFRTKMYGEYKGGRAKTPEELLEQMPYIQEMLHDLGIKTYELKNYEADDIIGTFA  123
            DAGK TFRT MY++YK+GRAKTP+E+ EQ +YI+EML  LGI  YEL +YEADDIIGT+ 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  124  AKGEKAG--FTTTIVTGDRDLTQLASDKTTVEVTKSGVSQLEAYTPEHMKEVNGVTPTEF  181
              +E++   F  TIV+GD+DL QL+ ++T VE++K GV+++E +TP  + E  G+TP +F
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  182  IDMKALMGDNSDNYPGVEGIGPKTASNLIQEYGSVENLYDHIDEMKKSKRKERLIRdkdk  241
            ID+KALMGD+SDN PGV  IG KT+ +L++E+GS+E +Y+HID  K SK KE LI D+D+
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRDQ  244

Query  242  aflakklaTIDRDSPVTIDIDDVKREPVDYEKLWQFYEKMNFRKFLAELNASGAGQDGAE  301
            AFL+K LATI+  SP+TI++DD+  +  D   L QFY+ M+F ++   L AS   Q+   
Sbjct  245  AFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGL-ASQMPQEPVA  303

Query  302  VEKVEYTVLNDDNVKDVKAT--EKDTVEFYLEMLGANYHLADFVGFSLKINDKIYVSRDV  359
            V  + Y     ++V +V A     + + FY+E L  NYH   ++GF+    ++IY S D+
Sbjct  304  V--ISY-----QEVTNVSADLFSAEDI-FYFETLRDNYHREAIIGFAWGHGEQIYASTDL  355

Query  360  DLLEEDNIKHILEDEKIKKNVFDLKRSMVGAHRLGIHTHGLDYDMLLASYLVNNENNSND  419
             LL  D++K++++        +D+KRS V   +LGI+  +  YD  LA+YL++  ++ N+
Sbjct  356  SLLATDSFKQVFQKPI---ATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NE  411

Query  420  LGEIAHLYGDYSVKTDLEVYGKGKSEHIPDDDDELFNHLASKVNAIESlkktlleklkDH  479
            L+ IA+++ D S+  D  VYGKG    +PD D  L++HLA KV+ +   K  +L+KL  H
Sbjct  412  LSTIARIFTDISLEEDDTVYGKGAKRAVPDKD-VLLEHLARKVKVLLDSKSQMLDKLTAH  470

Query  480  EQDDLFDTIEIPTARVLAKMEINGMKVEASTLIQLQNEFAVKLQDLEKKIYQQAGEEFNL  539
            EQ DL++ IE+P A VLAKMEI+G+KV+ +TL ++ ++  V ++ L + IY+ AG+EFN+
Sbjct  471  EQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNI  530

Query  540  NSPKQLGHILFEKLGLPV--LKKTKTGYSTSVEVLDQLKTQSPIVKEILDYRQIAKIQST  597
            NSPKQLG ILFEK+ LP+   KKTKTGYST+V+VL++L   +PIV  ILDYRQI+K+QST
Sbjct  531  NSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQST  590

Query  598  YVKGLLDVIQPDGRVHTRYLQTLTATGRLSSVDPNLQNIPTRTEEGKQIRKAFVPSDPDG  657
            YV GL D I +DG++HTRY+Q LT TGRLSSVDPNLQNIP R E+G+ IRKAF PS+ D+
Sbjct  591  YVIGLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDA  650

Query  658  YIFSCDYSQVELRVLAHVSGDVHMQEAFKTGYDIHSHTAMKIFHLDSPDKVTPLMRRHAK  717
             ++S DYSQ+ELRVLAH+SGD H+  AF+ G DIH+ TAM++F +D +  VT+  RR+AK
Sbjct  651  VLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAK  710

Query  718  AVNFGIVYGISDYGLSKNLGISRKQAKEFIDNYFEQYPQIKDYMDKAVQEAREKGYAETI  777
            AVNFGIVYGISD+GLS+NLGI+RKQ+K +ID YFE+YP IK YM++ V+EA++KGY ET+
Sbjct  711  AVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETL  770

Query  778  MHRRRYLPDIHAKKYTVRAFAERTAINSPIQGSAADIIKIAMINMQKKLDELHLKTKMVV  837
              RRR LPDI+++++ VR+FAERTAINSPIQGSAADI+KIAMIN++K L+   +++KM++
Sbjct  771  FKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLL  830

Query  838  QVHDELIFDVPKDELETIKKIVPEVMQSAVKLDVPLIADSGWGHNWYDAK  887
            QVHDE++++VP+DEL +IKK+V + M++AV L VPL  D + G++WY+AK
Sbjct  831  QVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

182) LAC30SC_08380 in NC_015214


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  769 bits (2911),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 477/890 (54%), Positives = 676/890 (76%), Gaps = 20/890 (2%)

Query  4    KKLLLIDGNSVAFRAFYALYRQLESFKSPDGLHTNAIYAFKNMLDVLLKDIDPTHVLVAF  63
            +KLLLIDG+SVAFRAF+ALY Q++ FK+  GLHTNAIY+F  MLD ++K + PTHVLVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  64   DAGKVTFRTKMYGEYKGGRAKTPEELLEQMPYIQEMLHDLGIKTYELKNYEADDIIGTFV  123
            DAGK TFRT MY++YK+GRAKTP+E+ EQ +YI+EML  LGI  YEL +YEADDIIGT+ 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  124  DKGEKNG--FTTTIVTGDRDLTQLASDKTTVEVTKSGVSQLEAYTPEHMKEVNGVTPTEF  181
              +E+    F  TIV+GD+DL QL+ ++T VE++K GV+++E +TP  + E  G+TP +F
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  182  IDMKALMGDSSDNYPGVTKVGPKTASRLIQKYGSVEGIYDHIDEMKKSKLKENLINdkdk  241
            ID+KALMGD SDN PGVTK+G KT+ +L++ +GS+EGIY+HID  K SK+KENLIND+D+
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRDQ  244

Query  242  aflakklaTIDRDSPVTLDIDDIKRQPVDYEKLRQFYEKMNFRKFLADLNASGAGQDSTE  301
            AFL+K LATI+  SP+T+++DDI  +  D   L QFY+ M+F ++  +L AS   Q++  
Sbjct  245  AFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGL-ASQMPQEPVA  303

Query  302  VEKVEYIVLNDDNVKDVKAT--EKDTVEFYLEMLGANYHLADFVGFSLKINDKIYVSRDV  359
            V  + Y     ++V +V A     + + FY+E L  NYH   ++GF+    ++IY S D+
Sbjct  304  V--ISY-----QEVTNVSADLFSAEDI-FYFETLRDNYHREAIIGFAWGHGEQIYASTDL  355

Query  360  ELLEEDNIKHILEDEKIKKNVFDLKRTMVAAHRLGIHTHGLDYDMLLASYLINNENNSND  419
             LL  D++K++++        +D+KR+ V   +LGI+  +  YD  LA+YL++  ++ N+
Sbjct  356  SLLATDSFKQVFQKPI---ATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NE  411

Query  420  LGEIAHLYGDYSVKTDLEVYGKGKSEHIPDDDDELFNHLASKVNAIeklkpellkklkeh  479
            L+ IA+++ D S+  D  VYGKG    +PD D  L++HLA KV+ +   K+++L KL  H
Sbjct  412  LSTIARIFTDISLEEDDTVYGKGAKRAVPDKD-VLLEHLARKVKVLLDSKSQMLDKLTAH  470

Query  480  eQDALFDTIEIPTARVLARMEMNGMKVEASTLIQLQNEFTVKLKELEDKIYGQAGEKFNL  539
            EQ  L++ IE+P A VLA+ME++G+KV+ +TL ++ ++  V +  L + IY+ AG+ FN+
Sbjct  471  EQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNI  530

Query  540  NSPKQLGHILFEKLGLPV--IKKTKTGYSTSVEVLDQLKTQSPIVSEILDYRQIAKIQST  597
            NSPKQLG ILFEK+ LP+   KKTKTGYST+V+VL++L   +PIV+ ILDYRQI+K+QST
Sbjct  531  NSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQST  590

Query  598  YVKGLLDVIQPDGRVHTRYLQTLTATGRLSSVDPNLQNIPTRTEEGKQIRKAFVPSEPDG  657
            YV GL D I +DG++HTRY+Q LT TGRLSSVDPNLQNIP R E+G+ IRKAF PS+ D+
Sbjct  591  YVIGLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDA  650

Query  658  YIFSCDYSQVELRVLAHVSGDQNMQEAFKTGYDIHSHTAMKIFHLDSPDQVTPLMRRHAK  717
             ++S DYSQ+ELRVLAH+SGD+++  AF+ G DIH+ TAM++F +D + +VT+  RR+AK
Sbjct  651  VLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAK  710

Query  718  AVNFGIVYGISDYGLSKNLGISRKRAQEFIDNYFEQYPQIKDYMDKAVQEARDKGYAETI  777
            AVNFGIVYGISD+GLS+NLGI+RK+++ +ID YFE+YP IK YM++ V+EA+DKGY ET+
Sbjct  711  AVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETL  770

Query  778  MHRRRYLPDIHAKKYTVRAFAERTAINSPIQGSAADIIKIAMINMQKKLDELHLKTKMVV  837
              RRR LPDI+++++ VR+FAERTAINSPIQGSAADI+KIAMIN++K L+   +++KM++
Sbjct  771  FKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLL  830

Query  838  QVHDELIFDVPKDELETIKKIVPEVMQSAVKLDVPLIADSGWGHNWYDAK  887
            QVHDE++++VP+DEL +IKK+V + M++AV L VPL  D + G++WY+AK
Sbjct  831  QVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

183) LC40_0841 in NC_017465


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  769 bits (2911),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 473/887 (54%), Positives = 667/887 (76%), Gaps = 15/887 (1%)

Query  3    KQLLLIDGNSIVFRAFFAMHNQMEKFTNQAGLHTAAIYGFKLMLDHILKEVQPDAALVAF  62
            ++LLLIDG+S+ FRAFFA+ NQ+++F N++GLHT AIYGF LMLDH++K V+P   LVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  63   DAGKTTFRTEKYADYKGSRDKTPGELVEQLPYVRKLVEASGLHAYELVNYEADDIIGTLA  122
            DAGKTTFRTE YADYK++R KTP+E+ EQ++Y+R ++ A G+  YEL +YEADDIIGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  123  KEGDQAG--FETMIVTGDRDLTQLATDHTTVAVTKRGVTQTEEFTPAYMQEKLGVTPRQY  180
            K ++++   F+  IV+GD+DL QL+ ++T V ++K+GV++ EEFTPAY+ EK+G+TP Q+
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  181  IDVKALMGDSSDNYPGVTKIGEKTAVSLIQEYGSLDGLYENIAAMKKSKRKENLINEEKI  240
            ID+KALMGD SDN PGVTKIGEKT++ L++E+GSL+G+YE+I + K SK KENLIN+   
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRDQ  244

Query  241  ARECQDLATIRRDAPLAIGLKDIAYQGPDEAALIDLYQELDFKSFLKELGAQEGGAQVDQ  300
            A   + LATI   +P++IGL DI Y+GPD A+L ++Y+E+DF  + K L++Q     V  
Sbjct  245  AFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEPV--  302

Query  301  APIEYQVLDEDNMVLVDQLGATVCFQLEMPDANYHESPLAGFVIGDGKRWLVSRNADLLT  360
            A I YQ + +   V  D ++A   F +E    NYH  ++ GF  G+G +   S +  LL+
Sbjct  303  AVISYQEVTN---VSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLA  359

Query  361  TAPLKKLLEDPAVEKDVFNAKAQLVGLHRLGVDLAGVNFDLLLASYLLNTSENANDLGVL  420
            T ++K++++ P      ++ K   V L +LG++L + ++D  LA+YLL+T E+ N+L+ +
Sbjct  360  TDSFKQVFQKPI---ATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NELSTI  415

Query  421  AAAHDYHQVQTDEEVYGKGAKRAIPADDEVFFTHLAKKARAIRDLKEPLYQQLTDNEQLP  480
            A       ++ D+ VYGKGAKRA+P D +V++ HLA+K + + D K  + ++LT +EQL 
Sbjct  416  ARIFTDISLEEDDTVYGKGAKRAVP-DKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLD  474

Query  481  LYEDIERPLSAVLAHMEITGIHVDAATLKEMGSKLVEREAELEQAIYQEAGEEFNINSPK  540
            LY++IE PL+ VLA MEI GI V+ ATL++M+ +       L Q IY+ AG+EFNINSPK
Sbjct  475  LYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPK  534

Query  541  QLGVILFEKMKLP--VIKKTKTGYSTAVDVLEKLADRAPIVQDILAYRQISKLQSTYITG  598
            QLG ILFEKM+LP  + KKTKTGYSTAVDVLE+LA  APIV  IL YRQI+KLQSTY+ G
Sbjct  535  QLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIG  594

Query  599  LLKVIHQDDQKIHTRYLQTLTATGRLSSVDPNLQNIPVRLEEGRQIRRAFTPSAPGWKIF  658
            L   I  D+ KIHTRY+Q LT TGRLSSVDPNLQNIP+RLE+GR IR+AFTPS  +  ++
Sbjct  595  LQDYILADG-KIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLL  653

Query  659  SSDYSQVELRVLAHVTGDKNMQADFLAGKDIHAATAKRIFHLQSEDEVTPNMRRQAKAVN  718
            SSDYSQ+ELRVLAH++GD ++ A F  G DIH++TA R+F ++   +VT+N RR+AKAVN
Sbjct  654  SSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVN  713

Query  719  FGIVYGISDYGLAQNIHVSRPQAHEFIQSYFKEFPGVEKYVHDIVELAKQQGYVETLTHR  778
            FGIVYGISD+GL++N+ ++R Q+  +I++YF  +PG+  Y++++V  AK++GYVETL  R
Sbjct  714  FGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKR  773

Query  779  RRYLPEIHAKSFTQRSFAERMAMNTPIQGSAADIIKIAMIRMEKALKERGLRARMLLQIH  838
            RR LP+I++++F  RSFAER A+N+PIQGSAADI+KIAMI ++KAL+  G+RA+MLLQ+H
Sbjct  774  RRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVH  833

Query  839  DELVFeapeeeiatleelVPSIMDSAVKLDVPLKVESKSGATWYDLK  885
            DE+V+E P++E++++  LV   M++AV L VPL V+  +G +WY+ K
Sbjct  834  DEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

184) LA14_1542 in NC_021181


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  767 bits (2903),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 473/887 (54%), Positives = 676/887 (77%), Gaps = 15/887 (1%)

Query  4    KKLLLIDGNSVAFRAFYALYRQLDRFTSPDGLHTNAIFTFKNMLDAILKQVDPTNILVAF  63
            +KLLLIDG+SVAFRAF+ALY Q+DRF +  GLHTNAI+ F  MLD ++K+V PT++LVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  64   DAGKVTFRTAMYKDYKGGRQKTPSELLEQMPVIREMLTDLGITSYELKNYEADDIIGTLS  123
            DAGK TFRT MY DYK+GR KTP E+ EQ + IREMLT LGI+ YEL +YEADDIIGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  124  KMGE--DAGYEVTVVTGDRDLTQLASDKTTVLITKNGVGDTEAYTPEHMKEVNGITPTEF  181
            KM+E  +  ++VT+V+GD+DL QL+ ++T V I+K+GV++ E +TP  + E  G+TP +F
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  182  IDMKALMGDNSDNYPGVEGIGPKTASNLIQKYGSVENLYDHIDDLKKSKRKERLIRdkdk  241
            ID+KALMGD+SDN PGV  IG KT+ +L++ +GS+E +Y+HID++K SK KE LI D+D+
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRDQ  244

Query  242  aflakklaaIDRESPVTVTLEDTIKKDPNYEKLRDLYERLGFRKFLAELNLETAGEDSGD  301
            AFL+K LA+I+  SP+T+ L+D + ++P+   L ++Y+ ++F ++   L  + + E  + 
Sbjct  245  AFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEPVAV  304

Query  302  TENYDYVELTEDNVAELDDLKENEISFYLEMLGDNYHLAPFEGFSLKVGDKVYVSKDIAL  361
                 Y E+T+ +     DL   E  FY+E L DNYH  ++ GF+   G+++Y S D++L
Sbjct  305  I---SYQEVTNVS----ADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSL  357

Query  362  LQEKPLKDILENRKIQKDVFDLKRMTVGLHRLDVIVEGLNYDMLLASYLVNNEKNSNDLG  421
            L   ++K+++++       +D+KR  V L +L++ + + +YD  LA+YL++   + N+L+
Sbjct  358  LATDSFKQVFQK---PIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTV-EDNELS  413

Query  422  EIAHLYDEYSIKTDLEVYGKGKKQAIPEDKEFFKHLAAKVCVIeklkpellkqlkeheQD  481
             IA+++ + S+  D  VYGKG K+A+P+   ++ HLA KV V+   K+++L +L  HEQ 
Sbjct  414  TIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQL  473

Query  482  DLFETIEIPTARVLAKMEINGIKVEASTLIELQNEFAVKLKELEDKIYKQAGEEFNLNSP  541
            DL++ IE+P A VLAKMEI+GIKV+ +TL ++ ++  V +  L + IY  AG+EFN+NSP
Sbjct  474  DLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSP  533

Query  542  KQLGHILFEKLNLP--VLKKTKTGYSTSVEVLDQLKTQSPIVSEILDYRQIAKIQSTYVK  599
            KQLG ILFEK++LP  + KKTKTGYST+V+VL++L   +PIV+ ILDYRQI+K+QSTYV 
Sbjct  534  KQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVI  593

Query  600  GLLDVIQRDGRVHTRYLQTLTATGRLSSVDPNLQNIPTRTEEGKQIRKAFVPSEPDGYIF  659
            GL D I  DG++HTRY+Q LT TGRLSSVDPNLQNIP R E+G+ IRKAF PS+ D+ ++
Sbjct  594  GLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLL  653

Query  660  SCDYSQVELRVLAHVSGDQNMQEAFKTGYDIHAHTAMRIFHLDSPDEVTPLMRRHAKAVN  719
            S DYSQ+ELRVLAH+SGD+++  AF+ G DIH+ TAMR+F +D + +VT+  RR+AKAVN
Sbjct  654  SSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVN  713

Query  720  FGIVYGISDYGLSKNLGISRKRAKEFIDNYFEQYPQIKDYMDKAVQEAREKGYAETIMHR  779
            FGIVYGISD+GLS+NLGI+RK++K +ID YFE+YP IK YM++ V+EA++KGY ET+  R
Sbjct  714  FGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKR  773

Query  780  RRYLPDIHAKKFTVRSFAERTAINSPIQGSAADIIKIAMINMQKKLDELHLKTKMVIQVH  839
            RR LPDI++++F VRSFAERTAINSPIQGSAADI+KIAMIN++K L+   +++KM++QVH
Sbjct  774  RRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVH  833

Query  840  DELIFDVPKDELETIKKIVPEIMQSAVKLDVPLIADSGWGHNWYDAK  886
            DE++++VP+DEL +IKK+V + M++AV L VPL  D + G++WY+AK
Sbjct  834  DEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

185) polA in NC_006814


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  767 bits (2903),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 473/887 (54%), Positives = 676/887 (77%), Gaps = 15/887 (1%)

Query  4    KKLLLIDGNSVAFRAFYALYRQLDRFTSPDGLHTNAIFTFKNMLDAILKQVDPTNILVAF  63
            +KLLLIDG+SVAFRAF+ALY Q+DRF +  GLHTNAI+ F  MLD ++K+V PT++LVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  64   DAGKVTFRTAMYKDYKGGRQKTPSELLEQMPVIREMLTDLGITSYELKNYEADDIIGTLS  123
            DAGK TFRT MY DYK+GR KTP E+ EQ + IREMLT LGI+ YEL +YEADDIIGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  124  KMGE--DAGYEVTVVTGDRDLTQLASDKTTVLITKNGVGDTEAYTPEHMKEVNGITPTEF  181
            KM+E  +  ++VT+V+GD+DL QL+ ++T V I+K+GV++ E +TP  + E  G+TP +F
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  182  IDMKALMGDNSDNYPGVEGIGPKTASNLIQKYGSVENLYDHIDDLKKSKRKERLIRdkdk  241
            ID+KALMGD+SDN PGV  IG KT+ +L++ +GS+E +Y+HID++K SK KE LI D+D+
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRDQ  244

Query  242  aflakklaaIDRESPVTVTLEDTIKKDPNYEKLRDLYERLGFRKFLAELNLETAGEDSGD  301
            AFL+K LA+I+  SP+T+ L+D + ++P+   L ++Y+ ++F ++   L  + + E  + 
Sbjct  245  AFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEPVAV  304

Query  302  TENYDYVELTEDNVAELDDLKENEISFYLEMLGDNYHLAPFEGFSLKVGDKVYVSKDIAL  361
                 Y E+T+ +     DL   E  FY+E L DNYH  ++ GF+   G+++Y S D++L
Sbjct  305  I---SYQEVTNVS----ADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSL  357

Query  362  LQEKPLKDILENRKIQKDVFDLKRMTVGLHRLDVIVEGLNYDMLLASYLVNNEKNSNDLG  421
            L   ++K+++++       +D+KR  V L +L++ + + +YD  LA+YL++   + N+L+
Sbjct  358  LATDSFKQVFQK---PIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTV-EDNELS  413

Query  422  EIAHLYDEYSIKTDLEVYGKGKKQAIPEDKEFFKHLAAKVCVIeklkpellkqlkeheQD  481
             IA+++ + S+  D  VYGKG K+A+P+   ++ HLA KV V+   K+++L +L  HEQ 
Sbjct  414  TIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQL  473

Query  482  DLFETIEIPTARVLAKMEINGIKVEASTLIELQNEFAVKLKELEDKIYKQAGEEFNLNSP  541
            DL++ IE+P A VLAKMEI+GIKV+ +TL ++ ++  V +  L + IY  AG+EFN+NSP
Sbjct  474  DLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSP  533

Query  542  KQLGHILFEKLNLP--VLKKTKTGYSTSVEVLDQLKTQSPIVSEILDYRQIAKIQSTYVK  599
            KQLG ILFEK++LP  + KKTKTGYST+V+VL++L   +PIV+ ILDYRQI+K+QSTYV 
Sbjct  534  KQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVI  593

Query  600  GLLDVIQRDGRVHTRYLQTLTATGRLSSVDPNLQNIPTRTEEGKQIRKAFVPSEPDGYIF  659
            GL D I  DG++HTRY+Q LT TGRLSSVDPNLQNIP R E+G+ IRKAF PS+ D+ ++
Sbjct  594  GLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLL  653

Query  660  SCDYSQVELRVLAHVSGDQNMQEAFKTGYDIHAHTAMRIFHLDSPDEVTPLMRRHAKAVN  719
            S DYSQ+ELRVLAH+SGD+++  AF+ G DIH+ TAMR+F +D + +VT+  RR+AKAVN
Sbjct  654  SSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVN  713

Query  720  FGIVYGISDYGLSKNLGISRKRAKEFIDNYFEQYPQIKDYMDKAVQEAREKGYAETIMHR  779
            FGIVYGISD+GLS+NLGI+RK++K +ID YFE+YP IK YM++ V+EA++KGY ET+  R
Sbjct  714  FGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKR  773

Query  780  RRYLPDIHAKKFTVRSFAERTAINSPIQGSAADIIKIAMINMQKKLDELHLKTKMVIQVH  839
            RR LPDI++++F VRSFAERTAINSPIQGSAADI+KIAMIN++K L+   +++KM++QVH
Sbjct  774  RRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVH  833

Query  840  DELIFDVPKDELETIKKIVPEIMQSAVKLDVPLIADSGWGHNWYDAK  886
            DE++++VP+DEL +IKK+V + M++AV L VPL  D + G++WY+AK
Sbjct  834  DEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

186) LA2_08635 in NC_014724


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  767 bits (2902),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 476/890 (54%), Positives = 675/890 (76%), Gaps = 20/890 (2%)

Query  4    KKLLLIDGNSVAFRAFYALYRQLESFKSPDGLHTNAIYAFKNMLDVLLKDIDPTHVLVAF  63
            +KLLLIDG+SVAFRAF+ALY Q++ FK+  GLHTNAIY+F  MLD ++K + PTHVLVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  64   DAGKVTFRTKMYGEYKGGRAKTPEELLEQMPYIQEMLHDLGIKTYELKNYEADDIIGTFV  123
            DAGK TFRT MY++YK+GRAKTP+E+ EQ +YI+EML  LGI  YEL +YEADDIIGT+ 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  124  DKGEKNG--FTTTVVTGDRDLTQLASDKTTVEVTKSGVSQLEAYTPEHMKEVNGVTPTEF  181
              +E+    F  T+V+GD+DL QL+ ++T VE++K GV+++E +TP  + E  G+TP +F
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  182  IDMKALMGDSSDNYPGVTKVGPKTASRLIQKYGSVEGIYDHIDEMKKSKLKENLINdkdk  241
            ID+KALMGD SDN PGVTK+G KT+ +L++ +GS+EGIY+HID  K SK+KENLIND+D+
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRDQ  244

Query  242  aflakklaTIDRDSPVTLDIDDIKRQPVDYEKLRQFYEKMNFRKFLADLNASGAGQDSTE  301
            AFL+K LATI+  SP+T+++DDI  +  D   L QFY+ M+F ++  +L AS   Q++  
Sbjct  245  AFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGL-ASQMPQEPVA  303

Query  302  VEKVEYIVLNDDNVKDVKAT--EKDTVEFYLEMLGANYHLADFVGFSLKINDKIYVSRDV  359
            V  + Y     ++V +V A     + + FY+E L  NYH   ++GF+    ++IY S D+
Sbjct  304  V--ISY-----QEVTNVSADLFSAEDI-FYFETLRDNYHREAIIGFAWGHGEQIYASTDL  355

Query  360  ELLEEDNIKHILEDEKIKKNVFDLKRTMVAAHRLGIHTQGLDYDMLLASYLINNENNSND  419
             LL  D++K++++        +D+KR+ V   +LGI+  +  YD  LA+YL++  ++ N+
Sbjct  356  SLLATDSFKQVFQKPI---ATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NE  411

Query  420  LGEIAHLYGDYSVKTDLEVYGKGKSEHIPDDDDELFNHLASKVNAIeklkpellkklkeh  479
            L+ IA+++ D S+  D  VYGKG    +PD D  L++HLA KV+ +   K+++L KL  H
Sbjct  412  LSTIARIFTDISLEEDDTVYGKGAKRAVPDKD-VLLEHLARKVKVLLDSKSQMLDKLTAH  470

Query  480  eQDALFDTIEIPTARVLARMEMNGMKVEASTLIQLQNEFAVKLKELEDKIYSQAGEKFNL  539
            EQ  L++ IE+P A VLA+ME++G+KV+ +TL ++ ++  V +  L + IY  AG+ FN+
Sbjct  471  EQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNI  530

Query  540  NSPKQLGHILFEKLGLPV--IKKTKTGYSTSVEVLDQLKMQSPIVSEILDYRQIAKIQST  597
            NSPKQLG ILFEK+ LP+   KKTKTGYST+V+VL++L   +PIV+ ILDYRQI+K+QST
Sbjct  531  NSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQST  590

Query  598  YVKGLLDVIQPDGRVHTRYLQTLTATGRLSSVDPNLQNIPTRTEEGKQIRKAFVPSEPDG  657
            YV GL D I +DG++HTRY+Q LT TGRLSSVDPNLQNIP R E+G+ IRKAF PS+ D+
Sbjct  591  YVIGLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDA  650

Query  658  YIFSCDYSQVELRVLAHVSGDQNMQEAFKTGYDIHSHTAMKIFHLDSPDQVTPLMRRHAK  717
             ++S DYSQ+ELRVLAH+SGD+++  AF+ G DIH+ TAM++F +D + +VT+  RR+AK
Sbjct  651  VLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAK  710

Query  718  AVNFGIVYGISDYGLSKNLGISRKRAQEFIDNYFEQYPQIKDYMDKAVQEARDKGYAETI  777
            AVNFGIVYGISD+GLS+NLGI+RK+++ +ID YFE+YP IK YM++ V+EA+DKGY ET+
Sbjct  711  AVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETL  770

Query  778  MHRRRYLPDIHAKKYTVRAFAERTAINSPIQGSAADIIKIAMINMQKKLDELHLKTKMVV  837
              RRR LPDI+++++ VR+FAERTAINSPIQGSAADI+KIAMIN++K L+   +++KM++
Sbjct  771  FKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLL  830

Query  838  QVHDELIFDVPKDELETIKKIVPEVMQSAVKLDVPLIADSGWGHNWYDAK  887
            QVHDE++++VP+DEL +IKK+V + M++AV L VPL  D + G++WY+AK
Sbjct  831  QVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

187) LAF_1317 in NC_010610


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  767 bits (2904),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 472/887 (54%), Positives = 665/887 (75%), Gaps = 15/887 (1%)

Query  3    KQLLLIDGNSIVFRAFFAMHNQMEKFTNQAGLHTAAIYGFKLMLDHILKEVQPDAALVAF  62
            ++LLLIDG+S+ FRAFFA+ NQ+++F N++GLHT AIYGF LMLDH++K V+P   LVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  63   DAGKTTFRTEKYADYKGSRDKTPGELVEQLPYVRKLVEASGLHAYELVNYEADDIIGTLA  122
            DAGKTTFRTE YADYK++R KTP+E+ EQ++Y+R ++ A G+  YEL +YEADDIIGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  123  KEGDQAG--FETMIVTGDRDLTQLATDHTTVAVTKRGVTQTEEFTPAYMQEKLGVTPRQY  180
            K ++++   F+  IV+GD+DL QL+ ++T V ++K+GV++ EEFTPAY+ EK+G+TP Q+
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  181  IDVKALMGDSSDNYPGVTKIGEKTAVSLIQEYGSLDGLYENIAAMKKSKRKENLINEEKI  240
            ID+KALMGD SDN PGVTKIGEKT++ L++E+GSL+G+YE+I + K SK KENLIN+   
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRDQ  244

Query  241  ARECQDLATIRRDAPLAIGLKDIAYQGPDEAALIDLYQELDFKSFLKELGAQEGGAQVDQ  300
            A   + LATI   +P++IGL DI Y+GPD A+L ++Y+E+DF  + K L++Q     V  
Sbjct  245  AFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEPV--  302

Query  301  APIEYQVLDEDNMALVDQLGATVCFQLEMPDANYHESPLAGFVIGDGKRWLVSRNADLLT  360
            A I YQ + + +  L   ++A   F +E    NYH  ++ GF  G+G +   S +  LL+
Sbjct  303  AVISYQEVTNVSADL---FSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLA  359

Query  361  TAPLKKLLEDPAVERDVFNAKAQLVGLHRLGVDLAGVDFDLLLASYLLNTSENANDLGVL  420
            T ++K++++ P      ++ K   V L +LG++L +  +D  LA+YLL+T E+ N+L+ +
Sbjct  360  TDSFKQVFQKPI---ATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NELSTI  415

Query  421  AAAHDYHQVQTDEEVYGKGAKRAIPADDEVFFTHLAKKARAIRDLKEPLYQQLTDNEQLP  480
            A       ++ D+ VYGKGAKRA+P D +V++ HLA+K + + D K  + ++LT +EQL 
Sbjct  416  ARIFTDISLEEDDTVYGKGAKRAVP-DKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLD  474

Query  481  LYEDIERPLSAVLAHMEITGIHVDAATLKEMGSKLVEREAELEQAIYQEAGEEFNINSPK  540
            LY++IE PL+ VLA MEI GI V+ ATL++M+ +       L Q IY+ AG+EFNINSPK
Sbjct  475  LYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPK  534

Query  541  QLGVILFEKMKLP--VIKKTKTGYSTAVDVLEKLADRAPIVQDILAYRQISKLQSTYITG  598
            QLG ILFEKM+LP  + KKTKTGYSTAVDVLE+LA  APIV  IL YRQI+KLQSTY+ G
Sbjct  535  QLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIG  594

Query  599  LLKVIHQDDQKIHTRYLQTLTATGRLSSVDPNLQNIPVRLEEGRQIRRAFTPSAPGWKIF  658
            L   I  D+ KIHTRY+Q LT TGRLSSVDPNLQNIP+RLE+GR IR+AFTPS  +  ++
Sbjct  595  LQDYILADG-KIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLL  653

Query  659  SSDYSQVELRVLAHVTGDKNMQADFLAGKDIHAATAKRIFHLQSEDEVTPNMRRQAKAVN  718
            SSDYSQ+ELRVLAH++GD ++ A F  G DIH++TA R+F ++   +VT+N RR+AKAVN
Sbjct  654  SSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVN  713

Query  719  FGIVYGISDYGLAQNIHVSRPQAHEFIQSYFKEFPGVEKYVHDIVELAKQQGYVETLTHR  778
            FGIVYGISD+GL++N+ ++R Q+  +I++YF  +PG+  Y++++V  AK++GYVETL  R
Sbjct  714  FGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKR  773

Query  779  RRYLPEIHAKSFTQRSFAERMAMNTPIQGSAADIIKIAMIRMEKALKERGLRARMLLQIH  838
            RR LP+I++++F  RSFAER A+N+PIQGSAADI+KIAMI ++KAL+  G+RA+MLLQ+H
Sbjct  774  RRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVH  833

Query  839  DELVFeapeeeiaileelvpSIMDSAVKLDVPLKVESKSGATWYDLK  885
            DE+V+E P++E++ +  LV   M++AV L VPL V+  +G +WY+ K
Sbjct  834  DEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

188) R0052_03345 in NC_018528


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  767 bits (2903),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 478/890 (54%), Positives = 672/890 (76%), Gaps = 20/890 (2%)

Query  4    KKLLLIDGNSVAFRAFYALYRQLESFKSPDGLHTNAIYAFKNMLDVLLKDVDPTHVLVAF  63
            +KLLLIDG+SVAFRAF+ALY Q++ FK+  GLHTNAIY+F  MLD ++K V PTHVLVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  64   DAGKVTFRTKMYGEYKGGRAKTPEELLEQMPYIQEMLHDLGIKTYELKNYEADDIIGTFA  123
            DAGK TFRT MY++YK+GRAKTP+E+ EQ +YI+EML  LGI  YEL +YEADDIIGT+ 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  124  AKGEKAG--FTTTIVTGDRDLTQLASDKTTVEVTKSGVSQLEAYTPEHMKEVNGVTPTEF  181
              +E++   F  TIV+GD+DL QL+ ++T VE++K GV+++E +TP  + E  G+TP +F
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  182  IDMKALMGDNSDNYPGVEGIGPKTASNLIQEYGSVENLYDHIDEMKKSKRKERLIRdkdk  241
            ID+KALMGD+SDN PGV  IG KT+ +L++E+GS+E +Y+HID  K SK KE LI D+D+
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRDQ  244

Query  242  aflakklaTIDRDSPVTIDIDDVKREPVDYEKLWQFYEKMNFRKFLAELNASGAGQDGAE  301
            AFL+K LATI+  SP+TI++DD+  +  D   L QFY+ M+F ++   L AS   Q+   
Sbjct  245  AFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGL-ASQMPQEPVA  303

Query  302  VEKVEYTVLNDDNVKDVKAT--EKDTVEFYLEMLGANYHLADFVGFSLKINDKIYVSRDV  359
            V  + Y     ++V +V A     + + FY+E L  NYH   ++GF+    ++IY S D+
Sbjct  304  V--ISY-----QEVTNVSADLFSAEDI-FYFETLRDNYHREAIIGFAWGHGEQIYASTDL  355

Query  360  DLLEEDNIKHILEDEKIKKNVFDLKRSMVGAHRLGIHTHGLDYDMLLASYLVNNENNSND  419
             LL  D++K++++        +D+KRS V   +LGI+  +  YD  LA+YL++  ++ N+
Sbjct  356  SLLATDSFKQVFQKPI---ATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NE  411

Query  420  LGEIAHLYGDYSVKTDLEVYGKGKSEHIPDDDDELFNHLASKVNAIESlkktlleklkDH  479
            L+ IA+++ D S+  D  VYGKG    +PD D  L++HLA KV+ +   K  +L+KL  H
Sbjct  412  LSTIARIFTDISLEEDDTVYGKGAKRAVPDKD-VLLEHLARKVKVLLDSKSQMLDKLTAH  470

Query  480  EQDDLFDTIEIPTARVLAKMEINGMKVEASTLIQLQNEFAVKLQDLEKKIYQQAGEEFNL  539
            EQ DL++ IE+P A VLAKMEI+G+KV+ +TL ++ ++  V ++ L + IY+ AG+EFN+
Sbjct  471  EQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNI  530

Query  540  NSPKQLGHILFEKLGLPV--LKKTKTGYSTSVEVLDQLKTQSPIVKEILDYRQIAKIQST  597
            NSPKQLG ILFEK+ LP+   KKTKTGYST+V+VL++L   +PIV  ILDYRQI+K+QST
Sbjct  531  NSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQST  590

Query  598  YVKGLLDVIQPDGRVHTRYLQTLTATGRLSSVDPNLQNIPTRTEEGKQIRKAFVPSDPDG  657
            YV GL D I +DG++HTRY+Q LT TGRLSSVDPNLQNIP R E+G+ IRKAF PS+ D+
Sbjct  591  YVIGLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDA  650

Query  658  YIFSCDYSQVELRVLAHVSGDQNMQEAFKTGYDIHSHTAMKIFHLESPDEVTPLMRRHAK  717
             ++S DYSQ+ELRVLAH+SGD+++  AF+ G DIH+ TAM++F ++ + +VT+  RR+AK
Sbjct  651  VLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAK  710

Query  718  AVNFGIVYGISDYGLSKNLGISRKRAQEFIDNYFEQYPQIKDYMNKAVQEARDKGYAETI  777
            AVNFGIVYGISD+GLS+NLGI+RK+++ +ID YFE+YP IK YM++ V+EA+DKGY ET+
Sbjct  711  AVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETL  770

Query  778  MHRRRYLPDIHAKKYTVRAFAERTAINSPIQGSAADIIKIAMINMQKKLDELHLKTKMVV  837
              RRR LPDI+++++ VR+FAERTAINSPIQGSAADI+KIAMIN++K L+   +++KM++
Sbjct  771  FKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLL  830

Query  838  QVHDELIFDVPKDELETIKKIVPEVMQSAVKLDVPLIADSGWGHNWYDAK  887
            QVHDE++++VP+DEL +IKK+V + M++AV L VPL  D + G++WY+AK
Sbjct  831  QVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

189) polA in NC_007929


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  767 bits (2903),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 480/895 (54%), Positives = 674/895 (76%), Gaps = 19/895 (2%)

Query  2    VEEKNKLLLIDGNSVTFRAFFALHNSLSRFVNHEGLHTNAIYGFKNMLDSILTKVNPTHI  61
            +E+KNKLLLIDG+SV+FRAFFAL N + RF NH GLHTNAIYGF  MLD ++ +V PTH+
Sbjct  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60

Query  62   LVAFDAGKTTFRTEKFTDYKGGRAKTPSELSEQFPEIKNLLEGYGIKTYELKNYEADDII  121
            LVAFDAGKTTFRTE ++DYK+GRAKTP E+ EQF+ I+++L + GI  YEL +YEADDII
Sbjct  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120

Query  122  GTLAAKAEKKN--YDVVVVTGDRDLTQLTTDKITVAVTVKGVSEIEEYTPSHVEEKIGLI  179
            GTL   AE+ +  +DV +V+GD+DL QLT ++  V ++ KGV+E+EE+TP+ + EK+GL 
Sbjct  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180

Query  180  PEQIVDMKALVGDTSDNYPGVTKIGEKTAIKLLKQYGTLDGIYKNIDEMKKSKMKENLIR  239
            P+Q++D+KAL+GD SDN PGVTKIGEKT++KLL ++G+L+GIY +ID  K SKMKENLI 
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  240  EKEIAYLCQDLAEIRKDAPVEIDLEETEWTGKNIEKLVTLYQKLDFRKFLSQLKAESSEQ  299
            +++ A+L + LA I   +P+ I+L++    G ++  L  +Y+ +DF     QLK   + Q
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDF----VQLKKGLASQ  296

Query  300  LDIFESKSNIEFTELTEENLNDIKISDNDEIVFNLEIDGENYHTAEIIGFSIKIGDKYLV  359
            +   E+ + I + E+T+ + + +   D    +F +E   +NYH   IIGF+   G++   
Sbjct  297  MPQ-EPVAVISYQEVTNVSADLFSAED----IFYFETLRDNYHREAIIGFAWGHGEQIYA  351

Query  360  SddidllkkkqiknllESDEVEVDLFDGKRQYVGLNRLGVTLSKINFDLLLVSYLLDNSE  419
            S D+ LL    +K++++     +  +D KR  V L++LG+ L   ++D  L +YLL   E
Sbjct  352  STDLSLLATDSFKQVFQK---PIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVE  408

Query  420  NSNDLGLLAQQHEYYDVESDEQIYGKGAKHAVPEDKEVLFEHLVRKVKAInnlkeklfne  479
            + N+L+ +A+      +E D+ +YGKGAK+AVP DK+VL+EHL RKVK + + K ++++ 
Sbjct  409  D-NELSTIARIFTDISLEEDDTVYGKGAKRAVP-DKDVLLEHLARKVKVLLDSKSQMLDK  466

Query  480  leenqqlDLYTKIERPLSIILANMEIAGVKVDSNRLETMQSELKERLSELEQEIYNEAGE  539
            L  ++QLDLY +IE PL+ +LA+MEI G+KV+   L+ M  + K  +  L QEIY+ AG+
Sbjct  467  LTAHEQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQ  526

Query  540  EFNLNSPKQLGVILFEKLKLP--VIKKTKTGYSTAVGVLEQLRGMSPIVDNILQYRQLAK  597
            EFN+NSPKQLG ILFEK++LP  + KKTKTGYSTAV+VLE+L  ++PIV +IL+YRQ++K
Sbjct  527  EFNINSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITK  586

Query  598  IQSTYIEGLLKVVSKKDGKAHTRYTQTLTSTGRLSSVDPNLQNIPVRLEEGRKIRQAFVP  657
            +QSTY+ GL   +   DGK HTRY Q LT TGRLSSVDPNLQNIP+RLE+GR IR+AF P
Sbjct  587  LQSTYVIGLQDYILA-DGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTP  645

Query  658  SHPGWEIFSSDYSQIELRVLAHISKDKNMQEAFKEGMDIHASTAMRIFNVDSPDEVTPNM  717
            SH +  ++SSDYSQIELRVLAHIS D ++  AF+EG DIH+STAMR+F +D + +VT+N 
Sbjct  646  SHEDAVLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTAND  705

Query  718  RRQAKAVNFGIVYGISDYGLSQNIGISRKQAKQFIDTYLDTFSGVKDYMEKIVEFAKENG  777
            RR+AKAVNFGIVYGISD+GLS+N+GI+RKQ+K +IDTY++ ++G+K YME++V  AK++G
Sbjct  706  RRNAKAVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKG  765

Query  778  YVETIFNRRRYLPDIKSRNFNLRSFAERTAMNSPIQGSAADIIKVAMINMQEMLKEKNLQ  837
            YVET+F+RRR LPDI+SRNFN+RSFAERTA+NSPIQGSAADI+K+AMIN++  L+   ++
Sbjct  766  YVETLFKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFR  825

Query  838  AKMLLQVHDELIFEAPTEEIPLLEDMVPKVMDSAVKLDVPLKVESKHGQTWFDTK  892
            AKMLLQVHDE+++E P +E+  +  +V   M++AV L VPL V+   GQ+W+++K
Sbjct  826  AKMLLQVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

190) polA in NC_004193


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  766 bits (2900),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 460/888 (52%), Positives = 679/888 (77%), Gaps = 22/888 (2%)

Query  3    NKLVLIDGNSIIYRAFFAL----PLLNNDKGVYTNGVYGFTTMLLRILEEEKPTHMLVAF  58
            NKL+LIDG+S+ +RAFFAL      ++N+ G+ TN++YGF  ML +++   +PTH+LVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  59   DAGKTTFRHSTYKEYKGGRQKTPPELSEQFPVLKELLDAFSIKYYQLDQYEADDIIGTLS  118
            DAGKTTFR   Y +YK+GR KTP E+ EQF+ ++E+L A++I YY+L++YEADDIIGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  119  KQADKKD--WEVTVISGDKDLLQLVSEQVTVSVTKKGISDIEKYTPAYMLEKMEITPDQI  176
            K A++ +   +VT++SGDKDL+QL  E+  V ++KKG++++E +TPAY++EKM +TP+Q+
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  177  IHLKALMGDSSDNIPGVPGVGEKTATKLLKQYENLENVYEHIDEISGKKLKENLSNHRED  236
            I+LKALMGD SDNIPGV  +GEKT+ KLL ++ +LE +YEHID +   K+KENL N+R++
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRDQ  244

Query  237  AFMSKELVTINRESPIEITLENLPYQGFQTSSVVQIFKDLGFQSLLSRVSEETEDDAEQP  296
            AF+SK L TIN  SPI I L+++ Y+G + +S+ Q++ +++F  L   ++ +  +++   
Sbjct  245  AFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEP---  301

Query  297  NIEMESIEFDVVENVTKDLFTDNDALYIEMLGENYHLIPIEGIAVVNKERASFIPTDIAL  356
               +  I ++ V NV+ DLF+ +D +Y+E L +NYH  +I G+A  + E+  + +TD++L
Sbjct  302  ---VAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQI-YASTDLSL  357

Query  357  -NSNIFKAWAEDPQKHKIVFDAKRTKVALLRNNINMQGIIFDSLLASYLLNPAENNHDIP  415
              ++ FK   +  QK    +D KR+KV L +  I++ +  +D+ LA+YLL+  E+N +++
Sbjct  358  LATDSFK---QVFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDN-ELS  413

Query  416  AIANRKSRSDVQFDEEVFGKGAKQKVPEADVLNEHVVRKTQLLFDLYPEMEEELGNNEQY  475
            +IA   +   ++ D+ V+GKGAK+ VP+ DVL EH+ RK ++L+D  ++M + L  +EQ 
Sbjct  414  TIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQL  473

Query  476  ELLKELEMPLALILAEVEHYGVQVDIDKLKDMGEDLKERLSTLEQEVYELAGETFNLNSP  535
            +L +++E+PLA +LA +E  G++V+   L+DM+E+ K  + +L QE+Y++AG+ FN+NSP
Sbjct  474  DLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSP  533

Query  536  KQLGPILFEKLGLP--VIKKTKTGYSTAADVLEQLENEHDIIPKLLMYRQLGKLQSTYIE  593
            KQLG+ILFEK+ LP  + KKTKTGYSTA DVLE+L     I++K+L YRQ+ KLQSTY+ 
Sbjct  534  KQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVI  593

Query  594  GLLKVVRKDTSRIHTRYNQALTQTGRLSSIEPNLQNIPIRLEEGRKIRQAFVPSKDNWIM  653
            GL   +  D ++IHTRY Q LTQTGRLSS++PNLQNIPIRLE+GR IR+AF PS ++ ++
Sbjct  594  GLQDYILAD-GKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVL  652

Query  654  FAADYSQIELRVLAHIAGDEKLIKAFKEDTDIHTQTAMDVFHVE-SDEVTSNMRRQAKAV  712
            +++DYSQIELRVLAHI+GDE LI AF+E++DIHT TAM VF ++ + +VT+N RR+AKAV
Sbjct  653  LSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAV  712

Query  713  NFGIVYGISDYGLSQNLGITRKEAKKFIERYFNSYPGVKTYMDEIVQEAKHKGFVSTIMK  772
            NFGIVYGISD+GLS+NLGITRK++K +I+ YF+ YPG+K+YM+++V+EAK+KG+V T+ K
Sbjct  713  NFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFK  772

Query  773  RRRYLPDITSRNFNMRSFAERTAMNTPIQGSAADIIKKAMIDLDHRLKEENLQANVLLQV  832
            RRR LPDI SRNFN+RSFAERTA+N+PIQGSAADI+K AMI+LD  L+   ++A++LLQV
Sbjct  773  RRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQV  832

Query  833  HDELILEAPENEIDKLKEIVPDVMENTVELDVPLKVDYSFGKSWFDAK  880
            HDE++LE P++E+  +K +V D ME +V+L VPL VD S G+SW++AK
Sbjct  833  HDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

191) polA in NC_017481


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  764 bits (2891),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 481/895 (54%), Positives = 673/895 (76%), Gaps = 19/895 (2%)

Query  2    VEEKNKLLLIDGNSVTFRAFFALHNSLSRFVNHEGLHTNAIYGFKNMLDSILTKVNPTHI  61
            +E+KNKLLLIDG+SV+FRAFFAL N + RF NH GLHTNAIYGF  MLD ++ +V PTH+
Sbjct  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60

Query  62   LVAFDAGKTTFRTEKFTDYKGGRAKTPSELSEQFPEIKNLLEGYRIKTYELKNYEADDII  121
            LVAFDAGKTTFRTE ++DYK+GRAKTP E+ EQF+ I+++L +  I  YEL +YEADDII
Sbjct  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120

Query  122  GTLAAKAEKKN--YDVVVVTGDRDLTQLTTDKITVAVTVKGVSEIEEYTPSHVEEKIGLI  179
            GTL   AE+ +  +DV +V+GD+DL QLT ++  V ++ KGV+E+EE+TP+ + EK+GL 
Sbjct  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180

Query  180  PEQIVDMKALVGDTSDNYPGVTKIGEKTAIKLLKQYGTLDGIYKNIDEMKKSKMKENLIR  239
            P+Q++D+KAL+GD SDN PGVTKIGEKT++KLL ++G+L+GIY +ID  K SKMKENLI 
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  240  EKEIAYLCQDLAEIRKDAPVEIDLEETEWTGKNIEKLVTLYQKLDFRKFLSQLKAESSEQ  299
            +++ A+L + LA I   +P+ I+L++    G ++  L  +Y+ +DF     QLK   + Q
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDF----VQLKKGLASQ  296

Query  300  LDIFESKSNIEFTELTEENLDDINVSDNDEIVFNLEIDGENYHTAEIIGFSIKIGDKYLV  359
            +   E+ + I + E+T+ + D ++  D    +F +E   +NYH   IIGF+   G++   
Sbjct  297  MPQ-EPVAVISYQEVTNVSADLFSAED----IFYFETLRDNYHREAIIGFAWGHGEQIYA  351

Query  360  SddidllkkkqiknllESDEVEVDLFDGKRQYVGLNRLGVTLSKINFDLLLVSYLLDNSE  419
            S D+ LL    +K++++     +  +D KR  V L++LG+ L   ++D  L +YLL   E
Sbjct  352  STDLSLLATDSFKQVFQK---PIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVE  408

Query  420  NSNDLGLLAQQHEYYDVESDEQIYGKGAKHAVPKDKEVLFEHLVRKVKAInnlkeklfne  479
            + N+L+ +A+      +E D+ +YGKGAK+AVP DK+VL+EHL RKVK + + K ++++ 
Sbjct  409  D-NELSTIARIFTDISLEEDDTVYGKGAKRAVP-DKDVLLEHLARKVKVLLDSKSQMLDK  466

Query  480  leenqqlDLYTKIERPLSIVLANMEIAGVKVDSNRLETMQSELKERLSELEQEIYNEAGE  539
            L  ++QLDLY +IE PL+ VLA+MEI G+KV+   L+ M  + K  +  L QEIY+ AG+
Sbjct  467  LTAHEQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQ  526

Query  540  EFNLNSPKQLGVILFEKLKLP--VIKKTKTGYSTAVGVLEQLRGMSPIVDNILQYRQLAK  597
            EFN+NSPKQLG ILFEK++LP  + KKTKTGYSTAV+VLE+L  ++PIV +IL+YRQ++K
Sbjct  527  EFNINSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITK  586

Query  598  IQSTYIEGLLKVVSKKDGKAHTRYTQTLTSTGRLSSVDPNLQNIPVRLEEGRKIRQAFVP  657
            +QSTY+ GL   +   DGK HTRY Q LT TGRLSSVDPNLQNIP+RLE+GR IR+AF P
Sbjct  587  LQSTYVIGLQDYILA-DGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTP  645

Query  658  SHPGWEIFSSDYSQIELRVLAHISKDKNMQEAFKEGMDIHASTAMRIFNVDSPDEVTPNM  717
            SH +  ++SSDYSQIELRVLAHIS D ++  AF+EG DIH+STAMR+F +D + +VT+N 
Sbjct  646  SHEDAVLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTAND  705

Query  718  RRQAKAVNFGIVYGISDYGLSQNIGISRKQAKQFIDTYLDTFSGVKDYMEKIVEFAKENG  777
            RR+AKAVNFGIVYGISD+GLS+N+GI+RKQ+K +IDTY++ ++G+K YME++V  AK++G
Sbjct  706  RRNAKAVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKG  765

Query  778  YVETIFNRRRYLPDIKSRNFNLRSFAERTAMNSPIQGSAADIIKVAMINMQEMLKEKNLQ  837
            YVET+F+RRR LPDI+SRNFN+RSFAERTA+NSPIQGSAADI+K+AMIN++  L+   ++
Sbjct  766  YVETLFKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFR  825

Query  838  AKMLLQVHDELIFEAPTKEIPLLEDMVPKVMDSAVKLDVPLKVESKHGQTWFDTK  892
            AKMLLQVHDE+++E P  E+  +  +V   M++AV L VPL V+   GQ+W+++K
Sbjct  826  AKMLLQVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

192) N134_06975 in NC_021872


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  763 bits (2887),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 458/893 (52%), Positives = 658/893 (74%), Gaps = 25/893 (2%)

Query  3    KQLLLIDGNSIVFRAFFAMHNQMDKFTNKDGLHTAAIYGFKLMLDHVLQNFKPDAALVAF  62
            ++LLLIDG+S+ FRAFFA+ NQ+D+F N  GLHT AIYGF LMLDH+++  +P   LVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  63   DAGKVTFRTKMYDDYKGGRNKTPNELTEQIPYVRELIKDSGLHSYELANYEADDIIGTLA  122
            DAGK TFRT MY DYK+GR KTP+E+ EQ++Y+RE++   G+  YEL +YEADDIIGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  123  KQAD--DAGYKTLIVTGDRDLTQLASENTTVAVTHKGVTDTEHYTPAHVKEKLGITPRQI  180
            K A+  +  +   IV+GD+DL QL+ ENT V ++ KGV++ E++TPA + EK+G+TP Q+
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  181  IDMKALMGDSSDNYPGVTKIGEKTAIKLVKQFGSVEELYDHIDDLKKSKMKEHLIEDEEV  240
            ID+KALMGD SDN PGVTKIGEKT++KL+ +FGS+E +Y+HID++K SKMKE+LI+D + 
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRDQ  244

Query  241  ARQCKTLATILRDAPIKIGLDDLQYQGPQTDDLIKFYKEMGFKSFLKKMdidgagdedea  300
            A   KTLATI   +PI IGLDD+ Y+GP+   L +FY EM+F  + K +  + + +    
Sbjct  245  AFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEPV--  302

Query  301  eiapidYTVLTKDNLDELGQ--LTGEVSFYLEMSEENYHTSPFAGFVIGNEGHWFTSRDV  358
                   +V++ +++ +++   +++E  FY+E   +NYH  ++ GF  G+  + ++S D+
Sbjct  303  -------AVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDL  355

Query  359  DLLKEAPLKDLLQSDSVKKNVFNAKAQIVGLHRLGIPLENINFDLLLASYLLNTNDNSND  418
             LL   ++K+++Q        ++ K   V L +LGI L   ++D  LA+YLL+T ++ N+
Sbjct  356  SLLATDSFKQVFQKPI---ATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NE  411

Query  419  LGQVAQEHGYDDVRTDEE--VYGKGAKRAVPDDDETFFSHLATKARAIEQLRKDLFAKLD  476
            L+ +A  + + D+  +E+  VYGKGAKRAVPD D  ++ HLA K + + + + +++ KL 
Sbjct  412  LSTIA--RIFTDISLEEDDTVYGKGAKRAVPDKD-VLLEHLARKVKVLLDSKSQMLDKLT  468

Query  477  ENKQTPLYTDIELPLTRVLAKMEIAGVHVDAQTLKDMGSKLTERLSEIESQIYQEAGEEF  536
             + Q  LY +IELPL+ VLAKMEI G+ V+  TL+DM+ +    +  +  +IY+ AG+EF
Sbjct  469  AHEQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEF  528

Query  537  NINSTKQLGHILFEKLKLP--VIKKTKTGYSTAVDVLEKLADKSPIVEQILEYRQIAKLQ  594
            NINS KQLG ILFEK++LP  + KKTKTGYSTAVDVLE+LA  +PIV +IL+YRQI+KLQ
Sbjct  529  NINSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQ  588

Query  595  STYITGLLKVIHSNDQKIHTRYLQTLTQTGRLSSVDPNLQNIPVRLPEGRLIRKAFIPSH  654
            STY+ GL   I +++ KIHTRY+Q LTQTGRLSSVDPNLQNIP+RL +GRLIRKAF PSH
Sbjct  589  STYVIGLQDYILADG-KIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSH  647

Query  655  EGWQIFSSDYSQVELRVLAHITGDKNLQEDFKNGEDIHASTARRIFHLAPDAEIDRNMRR  714
            E+  ++SSDYSQ+ELRVLAHI+GD +L   F++G DIH+STA R+F +   A++  N RR
Sbjct  648  EDAVLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRR  707

Query  715  RAKAVNFGIVYGISDYGLAQRIHVSRAEAHEFIQNYFHEFPDVKKYINDTIAFAKENGYV  774
             AKAVNFGIVYGISD+GL++ + ++R ++  +I+ YF+ +P++K Y+++ +  AK++GYV
Sbjct  708  NAKAVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYV  767

Query  775  ETITHRRRYLPDIHAKSFSKRSFAERTAMNTPIQGSAADIIKIAMIRMQDELEKRHLKAK  834
            ET+  RRR LPDI++++F+ RSFAERTA+N+PIQGSAADI+KIAMI ++  L+   ++AK
Sbjct  768  ETLFKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAK  827

Query  835  MLLQIHDELVFEAPKEEIPVLSELVPKVMDSAVKLDVPLKVDSKYGDTWYDLK  887
            MLLQ+HDE+V+E P++E+  +  LV   M++AV L VPL VD   G++WY+ K
Sbjct  828  MLLQVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

193) PEPE_0688 in NC_008525


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  762 bits (2882),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 479/890 (54%), Positives = 679/890 (77%), Gaps = 16/890 (1%)

Query  2    AKDKLLLIDGNSIAFRSFFALHNSLSKFVNKNGLHTNAIFGFNKMLDSILEQYQPTAALV  61
             K+KLLLIDG+S+AFR+FFAL N + +F N +GLHTNAI+GF+ MLD ++ + +PT  LV
Sbjct  3    NKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLV  62

Query  62   AFDAGKTTFRNGKFDNYKGGRSKTPPELSEQMPYLRELLTGYGIKSYELPNYEADDIIGT  121
            AFDAGKTTFR   + +YK+GR+KTP E+ EQ +Y+RE+LT+ GI  YEL +YEADDIIGT
Sbjct  63   AFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGT  122

Query  122  LAKEAEAQD--YAVVVVTGDRDLTQLSSEKTIVAVTKKGVSEVEEYTPAYVEEKLGVTPK  179
            L K AE  +  + V +V+GD+DL QL+ E+T+V ++KKGV+E EE+TPAY+ EK+G+TP+
Sbjct  123  LDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPN  182

Query  180  QIIDIKGLAGDTSDNYPGVTKVGEKTAIKLLKQFDSLENLYEHLDELKPSKMKEHLIEDR  239
            Q+ID+K+L GD SDN PGVTK+GEKT++KLL +F+SLE +YEH+D +K SKMKE+LI+DR
Sbjct  183  QFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDR  242

Query  240  DNAFISKDLATIRRDAPIEISLDDVQYAGINEEYLREFYHQMNFKSFLSKLDQTATQDGV  299
            D+AF+SK LATI   +PI I+LDD+ Y G +   L +FY++M+F  +   L     Q+ V
Sbjct  243  DQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEPV  302

Query  300  EAVKKEVVFNVLNKDNVEQLQSLKGEIDFYLEMLDKNYHLSDFTGFVIGNADNIWVSDDV  359
              +  + V NV       +L  + +E  FY+E L  NYH   + GF  G++++I  S D+
Sbjct  303  AVISYQEVTNV-----SADL--FSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDL  355

Query  360  ELLNNSKIKAILEDPKIKINVFDSKRTYVGLHRLGIKLTAVNFDILLQSYLLDTNDNSND  419
             LL    +K +++ P   I  +D KR+ V L +LGI L A ++D  L +YLL T ++ N+
Sbjct  356  SLLATDSFKQVFQKP---IATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NE  411

Query  420  LGQLAHEHdydaidtdddVYGKGAKRAVPEQTELFNHLARKLAAINFLGKQLDQELVKNE  479
            L+ +A+     +++ DD VYGKGAKRAVP++  L++HLARK+  +     Q+ + L  +E
Sbjct  412  LSTIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHE  471

Query  480  QNNLYWDIELPLAIVLAKMEISGIKVDRNRLNQMQSEFTERLSEIETNIYNEAGEEFNLN  539
            Q +LY +IELPLA VLAKMEI GIKV+R  L++M  +    +  +  +IY+ AG+EFN+N
Sbjct  472  QLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNIN  531

Query  540  SPKQLGVVLFEklklp--iikktktGYSTAVDVLEKLQGESPIIDNILNYRTLSKIKSTY  597
            SPKQLG +LFEK++LP  + KKTKTGYSTAVDVLE+L   +PI+ +IL+YR ++K++STY
Sbjct  532  SPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTY  591

Query  598  VDGLLKVIHTTDEKVHTTYVQTLTQTGRLSSIDPNLQNIPVRIEEGRKIRQAFVPAREGW  657
            V GL   I  +D K+HT YVQ LTQTGRLSS+DPNLQNIP+R+E+GR IR+AF P++E+ 
Sbjct  592  VIGLQDYI-LADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDA  650

Query  658  HILSSDYSQIELRVLAHITGDQNLQEAFKNGEDIHATTAVKIFGLKDASEVTPNIRRQAK  717
             +LSSDYSQIELRVLAHI+GD++L  AF++G DIH++TA+++FG+  A++VT+N RR+AK
Sbjct  651  VLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAK  710

Query  718  AVNFGIVYGISDYGLSQNIGISRKDAKKFIETYFKEFPGVKKYIDESVQLAKEQGYVETI  777
            AVNFGIVYGISD+GLS+N+GI+RK++K +I+TYF  +PG+K Y+++ V+ AK++GYVET+
Sbjct  711  AVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETL  770

Query  778  AHRRRYLPDINSSSFNLRSFAERTAMNTPIQGSaadiikiamidmENELEKRNLKSRMLL  837
              RRR LPDINS +FN+RSFAERTA+N+PIQGSAADI+KIAMI++++ L+   ++++MLL
Sbjct  771  FKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLL  830

Query  838  QVHDELIFEVPDEEMTLMKELVPKVMDSAVKLDVPLKVGAAWGNTWYDAK  887
            QVHDE+++EVP++E+T +K LV   M++AV L VPL V+ + G++WY+AK
Sbjct  831  QVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

194) polA in NC_015697


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  760 bits (2877),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 459/893 (52%), Positives = 657/893 (74%), Gaps = 25/893 (2%)

Query  3    KQLLLIDGNSIVFRAFFAMHNQMDKFTNKDGLHTAAIYGFKLMLDHVLQNFKPDTALVAF  62
            ++LLLIDG+S+ FRAFFA+ NQ+D+F N  GLHT AIYGF LMLDH+++  +P   LVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  63   DAGKVTFRTKMYDDYKGGRNKTPNELTEQIPYVRELIKDSGLHSYELANYEADDIIGTLA  122
            DAGK TFRT MY DYK+GR KTP+E+ EQ++Y+RE++   G+  YEL +YEADDIIGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  123  KQAD--DAGYKTLIVTGDRDLTQLASENTTVAVTHKGVTDTEHYTPAHVEEKLGITPRQI  180
            K A+  +  +   IV+GD+DL QL+ ENT V ++ KGV++ E++TPA + EK+G+TP Q+
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  181  IDMKALMGDSSDNYPGVTKIGEKTAIKLVKQFGSVEELYDHIDDLKKSKMKEHLIEDEEI  240
            ID+KALMGD SDN PGVTKIGEKT++KL+ +FGS+E +Y+HID++K SKMKE+LI+D + 
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRDQ  244

Query  241  ARQCKTLATILRDAPLKIGLDDLQYQGPQTDDLIKFYKEMGFKSFLKKMdidgageedea  300
            A   KTLATI   +P+ IGLDD+ Y+GP+   L +FY EM+F  + K +  + + E    
Sbjct  245  AFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEPV--  302

Query  301  eiapidYTVLTKDNLDELGQ--LTGEVSFYLEMPAENYHTSPFAGFVIGNEGHWFTSRDV  358
                   +V++ +++ +++   +++E  FY+E   +NYH  ++ GF  G+  + ++S D+
Sbjct  303  -------AVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDL  355

Query  359  DLLKEAPLKDLLQSDSVKKNVFNAKAQIVGLHRLGIPLENINFDLLLASYLLNTNDNSND  418
             LL   ++K+++Q        ++ K   V L +LGI L   ++D  LA+YLL+T ++ N+
Sbjct  356  SLLATDSFKQVFQKPI---ATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NE  411

Query  419  LGQVAQEHGYDDVRTDEE--VYGKGAKRAVPDDDETFFSHLATKARAIEHLRKDFFAKLD  476
            L+ +A  + + D+  +E+  VYGKGAKRAVPD D  ++ HLA K + + + + + + KL 
Sbjct  412  LSTIA--RIFTDISLEEDDTVYGKGAKRAVPDKD-VLLEHLARKVKVLLDSKSQMLDKLT  468

Query  477  ENKQTPLYTDIELPLTRVLAKMEIAGVHVDAQTLKDMGSKLTERLSEIESQIYQEAGEEF  536
             + Q  LY +IELPL+ VLAKMEI G+ V+  TL+DM+ +    +  +  +IY+ AG+EF
Sbjct  469  AHEQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEF  528

Query  537  NINSTKQLGHILFEKLKLP--VIKKTKTGYSTAVDVLEKLADKSPIVEQILEYRQIAKLQ  594
            NINS KQLG ILFEK++LP  + KKTKTGYSTAVDVLE+LA  +PIV +IL+YRQI+KLQ
Sbjct  529  NINSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQ  588

Query  595  STYITGLLKVIHSNDQKIHTRYLQTLTQTGRLSSVDPNLQNIPVRLPEGRLIRKAFVPSH  654
            STY+ GL   I +++ KIHTRY+Q LTQTGRLSSVDPNLQNIP+RL +GRLIRKAF PSH
Sbjct  589  STYVIGLQDYILADG-KIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSH  647

Query  655  EGWQIFSSDYSQVELRVLAHITGDKNLQEDFKNGEDIHASTARRIFHLAPDAEIDRNMRR  714
            E+  ++SSDYSQ+ELRVLAHI+GD +L   F++G DIH+STA R+F +   A++  N RR
Sbjct  648  EDAVLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRR  707

Query  715  RAKAVNFGIVYGISDYGLAQRIHVSRAEAHEFIQNYFHEFPGVKKYINDTIAFAKENGYV  774
             AKAVNFGIVYGISD+GL++ + ++R ++  +I+ YF+ +PG+K Y+++ +  AK++GYV
Sbjct  708  NAKAVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYV  767

Query  775  ETITHRRRYLPDIHAKSFSKRSFAERTAMNTPIQGSAADIIKIAMIRMQDELEKRHLKAK  834
            ET+  RRR LPDI++++F+ RSFAERTA+N+PIQGSAADI+KIAMI ++  L+   ++AK
Sbjct  768  ETLFKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAK  827

Query  835  MLLQIHDELVFEAPKEEIPILSELVPKVMDSAVKLDVPLKVDSKYGDTWYDLK  887
            MLLQ+HDE+V+E P++E+  +  LV   M++AV L VPL VD   G++WY+ K
Sbjct  828  MLLQVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

195) Lreu_1247 in NC_009513


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  759 bits (2873),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 463/891 (52%), Positives = 660/891 (75%), Gaps = 21/891 (2%)

Query  3    KQLLLIDGNSIVFRAFFAMHNQMDKFTNKDGLHTAAIYGFKLMLDHVLQNFKPDAALVAF  62
            ++LLLIDG+S+ FRAFFA+ NQ+D+F N  GLHT AIYGF LMLDH+++  +P   LVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  63   DAGKVTFRTKMYDDYKGGRNKTPNELTEQIPYVRELIKDSGLHSYELANYEADDIIGTLA  122
            DAGK TFRT MY DYK+GR KTP+E+ EQ++Y+RE++   G+  YEL +YEADDIIGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  123  KQAD--DAGYKTLIVTGDRDLTQLASENTTVAVTHKGVTDTEHYTPAHVEEKLGITPRQI  180
            K A+  +  +   IV+GD+DL QL+ ENT V ++ KGV++ E++TPA + EK+G+TP Q+
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  181  IDMKALMGDSSDNYPGVTKIGEKTAIKLVKQFGSVEELYDHIDDLKKSKMKEHLIEDEEV  240
            ID+KALMGD SDN PGVTKIGEKT++KL+ +FGS+E +Y+HID++K SKMKE+LI+D + 
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRDQ  244

Query  241  ARQCKTLATILQDAPIKIGLDDLQYQGPQTDDLIKFYKEMGFKSFLKKMDVDGTGEEDEA  300
            A   KTLATI   +PI IGLDD+ Y+GP+   L +FY EM+F  + K +    +++  + 
Sbjct  245  AFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGL----ASQMPQE  300

Query  301  EIAPIDYTVLTKDNLDELGQLTGEVSFYLEMPEENYHTSPFAGFVIGNEGHWFTSRDVdl  360
             +A I Y  +T+ +  +L  +++E  FY+E   +NYH  ++ GF  G+  + ++S D+ L
Sbjct  301  PVAVISYQEVTNVS-ADL--FSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSL  357

Query  361  lkeeplkdllQSDSVKKNVFNAKAQIVGLHRLGIPLENINFDLLLASYLLNTNDNSNDLG  420
            L  +++K+++Q        ++ K   V L +LGI L   ++D  LA+YLL+T ++ N+L+
Sbjct  358  LATDSFKQVFQKPI---ATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NELS  413

Query  421  QVAQEHGYDDVRTDEE--VYGKGAKRAVPDDDETFFSHLATKARAIEQLRKDLFAKLDEN  478
             +A  + + D+  +E+  VYGKGAKRAVPD D  ++ HLA K + + + + +++ KL  +
Sbjct  414  TIA--RIFTDISLEEDDTVYGKGAKRAVPDKD-VLLEHLARKVKVLLDSKSQMLDKLTAH  470

Query  479  KQTPLYTDIELPLTRVLAKMEIAGVHVDAQTLKDMGSKLTERLSEIESQIYQEAGEEFNI  538
             Q  LY +IELPL+ VLAKMEI G+ V+  TL+DM+ +    +  +  +IY+ AG+EFNI
Sbjct  471  EQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNI  530

Query  539  NSTKQLGHILFEKLKLP--VIKKTKTGYSTAVDVLEKLADKSPIVEQILEYRQIAKLQST  596
            NS KQLG ILFEK++LP  + KKTKTGYSTAVDVLE+LA  +PIV +IL+YRQI+KLQST
Sbjct  531  NSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQST  590

Query  597  YITGLLKVIHSNDQKIHTRYLQTLTQTGRLSSVDPNLQNIPVRLPEGRLIRKAFVPSHEG  656
            Y+ GL   I +++ KIHTRY+Q LTQTGRLSSVDPNLQNIP+RL +GRLIRKAF PSHE+
Sbjct  591  YVIGLQDYILADG-KIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHED  649

Query  657  WQIFSSDYSQVELRVLAHITGDKNLQEDFKNGEDIHASTARRIFHLAPDAEIDRNMRRRA  716
              ++SSDYSQ+ELRVLAHI+GD +L   F++G DIH+STA R+F +   A++  N RR A
Sbjct  650  AVLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNA  709

Query  717  KAVNFGIVYGISDYGLAQRIHVSRAEAHEFIQNYFHEFPGVKKYINDTIAFAKENGYVET  776
            KAVNFGIVYGISD+GL++ + ++R ++  +I+ YF+ +PG+K Y+++ +  AK++GYVET
Sbjct  710  KAVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVET  769

Query  777  ITHRRRYLPDIHAKSFNKRSFAERTAMNTPIQGSAADIIKIAMIRMQDELEKRHLKAKMI  836
            +  RRR LPDI++++FN RSFAERTA+N+PIQGSAADI+KIAMI ++  L+   ++AKM+
Sbjct  770  LFKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKML  829

Query  837  LQIHDELVFEAPKEEIPVLSELVPKVMDSAVKLDVPLKVDSKYGDTWYDLK  887
            LQ+HDE+V+E P++E+  +  LV   M++AV L VPL VD   G++WY+ K
Sbjct  830  LQVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

196) LAR_1181 in NC_010609


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  759 bits (2873),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 463/891 (52%), Positives = 660/891 (75%), Gaps = 21/891 (2%)

Query  3    KQLLLIDGNSIVFRAFFAMHNQMDKFTNKDGLHTAAIYGFKLMLDHVLQNFKPDAALVAF  62
            ++LLLIDG+S+ FRAFFA+ NQ+D+F N  GLHT AIYGF LMLDH+++  +P   LVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  63   DAGKVTFRTKMYDDYKGGRNKTPNELTEQIPYVRELIKDSGLHSYELANYEADDIIGTLA  122
            DAGK TFRT MY DYK+GR KTP+E+ EQ++Y+RE++   G+  YEL +YEADDIIGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  123  KQAD--DAGYKTLIVTGDRDLTQLASENTTVAVTHKGVTDTEHYTPAHVEEKLGITPRQI  180
            K A+  +  +   IV+GD+DL QL+ ENT V ++ KGV++ E++TPA + EK+G+TP Q+
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  181  IDMKALMGDSSDNYPGVTKIGEKTAIKLVKQFGSVEELYDHIDDLKKSKMKEHLIEDEEV  240
            ID+KALMGD SDN PGVTKIGEKT++KL+ +FGS+E +Y+HID++K SKMKE+LI+D + 
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRDQ  244

Query  241  ARQCKTLATILQDAPIKIGLDDLQYQGPQTDDLIKFYKEMGFKSFLKKMDVDGTGEEDEA  300
            A   KTLATI   +PI IGLDD+ Y+GP+   L +FY EM+F  + K +    +++  + 
Sbjct  245  AFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGL----ASQMPQE  300

Query  301  EIAPIDYTVLTKDNLDELGQLTGEVSFYLEMPEENYHTSPFAGFVIGNEGHWFTSRDVdl  360
             +A I Y  +T+ +  +L  +++E  FY+E   +NYH  ++ GF  G+  + ++S D+ L
Sbjct  301  PVAVISYQEVTNVS-ADL--FSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSL  357

Query  361  lkeeplkdllQSDSVKKNVFNAKAQIVGLHRLGIPLENINFDLLLASYLLNTNDNSNDLG  420
            L  +++K+++Q        ++ K   V L +LGI L   ++D  LA+YLL+T ++ N+L+
Sbjct  358  LATDSFKQVFQKPI---ATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NELS  413

Query  421  QVAQEHGYDDVRTDEE--VYGKGAKRAVPDDDETFFSHLATKARAIEQLRKDLFAKLDEN  478
             +A  + + D+  +E+  VYGKGAKRAVPD D  ++ HLA K + + + + +++ KL  +
Sbjct  414  TIA--RIFTDISLEEDDTVYGKGAKRAVPDKD-VLLEHLARKVKVLLDSKSQMLDKLTAH  470

Query  479  KQTPLYTDIELPLTRVLAKMEIAGVHVDAQTLKDMGSKLTERLSEIESQIYQEAGEEFNI  538
             Q  LY +IELPL+ VLAKMEI G+ V+  TL+DM+ +    +  +  +IY+ AG+EFNI
Sbjct  471  EQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNI  530

Query  539  NSTKQLGHILFEKLKLP--VIKKTKTGYSTAVDVLEKLADKSPIVEQILEYRQIAKLQST  596
            NS KQLG ILFEK++LP  + KKTKTGYSTAVDVLE+LA  +PIV +IL+YRQI+KLQST
Sbjct  531  NSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQST  590

Query  597  YITGLLKVIHSNDQKIHTRYLQTLTQTGRLSSVDPNLQNIPVRLPEGRLIRKAFVPSHEG  656
            Y+ GL   I +++ KIHTRY+Q LTQTGRLSSVDPNLQNIP+RL +GRLIRKAF PSHE+
Sbjct  591  YVIGLQDYILADG-KIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHED  649

Query  657  WQIFSSDYSQVELRVLAHITGDKNLQEDFKNGEDIHASTARRIFHLAPDAEIDRNMRRRA  716
              ++SSDYSQ+ELRVLAHI+GD +L   F++G DIH+STA R+F +   A++  N RR A
Sbjct  650  AVLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNA  709

Query  717  KAVNFGIVYGISDYGLAQRIHVSRAEAHEFIQNYFHEFPGVKKYINDTIAFAKENGYVET  776
            KAVNFGIVYGISD+GL++ + ++R ++  +I+ YF+ +PG+K Y+++ +  AK++GYVET
Sbjct  710  KAVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVET  769

Query  777  ITHRRRYLPDIHAKSFNKRSFAERTAMNTPIQGSAADIIKIAMIRMQDELEKRHLKAKMI  836
            +  RRR LPDI++++FN RSFAERTA+N+PIQGSAADI+KIAMI ++  L+   ++AKM+
Sbjct  770  LFKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKML  829

Query  837  LQIHDELVFEAPKEEIPVLSELVPKVMDSAVKLDVPLKVDSKYGDTWYDLK  887
            LQ+HDE+V+E P++E+  +  LV   M++AV L VPL VD   G++WY+ K
Sbjct  830  LQVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

197) LRI_0722 in NC_021494


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  758 bits (2869),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 457/893 (52%), Positives = 657/893 (74%), Gaps = 25/893 (2%)

Query  3    KQLLLIDGNSIVFRAFFAMHNQMDKFTNKDGLHTAAIYGFKLMLDHVLQNFKPDTALVAF  62
            ++LLLIDG+S+ FRAFFA+ NQ+D+F N  GLHT AIYGF LMLDH+++  +P   LVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  63   DAGKVTFRTKMYDDYKGGRNKTPNELTEQIPYVRELIKDSGLHSYELANYEADDIIGTLA  122
            DAGK TFRT MY DYK+GR KTP+E+ EQ++Y+RE++   G+  YEL +YEADDIIGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  123  KQAD--DAGYKTLIVTGDRDLTQLASENTTVAVTHKGVTDTEHYTPAHVEEKLGITPRQI  180
            K A+  +  +   IV+GD+DL QL+ ENT V ++ KGV++ E++TPA + EK+G+TP Q+
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  181  IDMKALMGDSSDNYPGVTKIGEKTAIKLVKQFGSVEELYDHIDDLKKSKMKEHLIEDEEI  240
            ID+KALMGD SDN PGVTKIGEKT++KL+ +FGS+E +Y+HID++K SKMKE+LI+D + 
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRDQ  244

Query  241  ARQCKTLATILRDAPLKIGLDDLQYQGPQTDDLIKFYKEMGFKSFLKKMdidgagdedea  300
            A   KTLATI   +P+ IGLDD+ Y+GP+   L +FY EM+F  + K +  + + +    
Sbjct  245  AFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEPV--  302

Query  301  eiapidYTVLTKDNLDELGQ--LTGEVSFYLEMPAENYHTSPFAGFVVGNEGHWFTSRDV  358
                   +V++ +++ +++   +++E  FY+E   +NYH  ++ GF  G+  + ++S D+
Sbjct  303  -------AVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDL  355

Query  359  DLLKEAPLKDLLQSDSVKKNVFNAKAQIVGLHRLGIPLENINFDLLLASYLLNTNDNSND  418
             LL   ++K+++Q        ++ K   V L +LGI L   ++D  LA+YLL+T ++ N+
Sbjct  356  SLLATDSFKQVFQKPI---ATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NE  411

Query  419  LGQVAQEHGYDDVRTDEE--VYGKGAKRAVPDDDETFFSHLATKARAIEHLRKDFFAKLD  476
            L+ +A  + + D+  +E+  VYGKGAKRAVPD D  ++ HLA K + + + + + + KL 
Sbjct  412  LSTIA--RIFTDISLEEDDTVYGKGAKRAVPDKD-VLLEHLARKVKVLLDSKSQMLDKLT  468

Query  477  ENKQTPLYTDIELPLTRVLAKMEIAGVHVDAQTLKDMGSKLTERLSEIESQIYQEAGEEF  536
             + Q  LY +IELPL+ VLAKMEI G+ V+  TL+DM+ +    +  +  +IY+ AG+EF
Sbjct  469  AHEQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEF  528

Query  537  NINSTKQLGHILFEKLKLP--VIKKTKTGYSTAVDVLEKLADKSPIVEQILEYRQIAKLQ  594
            NINS KQLG ILFEK++LP  + KKTKTGYSTAVDVLE+LA  +PIV +IL+YRQI+KLQ
Sbjct  529  NINSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQ  588

Query  595  STYITGLLKVIHSNDQKIHTRYLQTLTQTGRLSSVDPNLQNIPVRLPEGRLIRKAFVPSH  654
            STY+ GL   I +++ KIHTRY+Q LTQTGRLSSVDPNLQNIP+RL +GRLIRKAF PSH
Sbjct  589  STYVIGLQDYILADG-KIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSH  647

Query  655  EGWQIFSSDYSQVELRVLAHITGDKNLQEDFKNDEDIHASTARRIFHLAPDAEIDRNMRR  714
            E+  ++SSDYSQ+ELRVLAHI+GD +L   F+++ DIH+STA R+F +   A++  N RR
Sbjct  648  EDAVLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRR  707

Query  715  RAKAVNFGIVYGISDYGLAQRIHVSRAEAHEFIQNYFHEFPGVKKYINDTIAFAKENGYV  774
             AKAVNFGIVYGISD+GL++ + ++R ++  +I+ YF+ +PG+K Y+++ +  AK++GYV
Sbjct  708  NAKAVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYV  767

Query  775  ETITHRRRYLPDIHAKSFSKRSFAERTAMNTPIQGSAADIIKIAMIRMQDELEKRHLKAK  834
            ET+  RRR LPDI++++F+ RSFAERTA+N+PIQGSAADI+KIAMI ++  L+   ++AK
Sbjct  768  ETLFKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAK  827

Query  835  MLLQIHDELVFEAPKEEIPVLSELVPKVMDSAVKLDVPLKVDSKYGDTWYDLK  887
            MLLQ+HDE+V+E P++E+  +  LV   M++AV L VPL VD   G++WY+ K
Sbjct  828  MLLQVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

198) polA in NC_015975


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  752 bits (2846),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 448/892 (51%), Positives = 660/892 (74%), Gaps = 19/892 (2%)

Query  1    MTEKQKLLLIDGNSITFRGFYALFMQTERFVNHDGLHTSAVFSFKRMLDKILDDVNPDKI  60
            M +K+KLLLIDG+S++FR+F+AL+ Q +RF NH GLHT+A+++F  MLD ++  V P  +
Sbjct  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60

Query  61   LVAFDAGKKTFRTEKYSDYKAGRKKTPEELSEQFPYVKKLLDCYGIKHYELKNYEADDII  120
            LVAFDAGK TFRTE Y+DYKAGR KTP+E+ EQF+Y++ +L   GI  YEL +YEADDII
Sbjct  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120

Query  121  GTMSKEAEKHG--YETTIVTGDRDLTQLVTNQTTVALTVKGVTEIEYYTPNHLSEKLGIS  178
            GT+ K AE+    ++ TIV+GD+DL QL  ++T V ++ KGV+E+E +TP  L EK+G++
Sbjct  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180

Query  179  PSQITDLKGLAGDTSDNYPGVSKVGEKTALKLLNQYGTIENLYEHIDEFKKSKMKEHLIE  238
            P+Q+ DLK+L GD SDN PGV+K+GEKT+LKLL+++G++E +YEHID FK SKMKE+LI+
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  239  DKEIALTCKNLATIRRDAPLEIGLADIDFAGKDIEKLREFYQSMDFHKFLSELNDKKSEE  298
            D++ A+  K LATI   +P+ IGL DI + G D+  L +FY+ MDF ++   L  + ++E
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQE  300

Query  299  VSNEEELPSIVELTFENID--GQRLNADNASFYLELADENYHTSPFWGFALLTDGQCYVS  356
                    ++  ++++++   +  L + +  FY+E   +NYH  ++ GFA   + Q Y S
Sbjct  301  --------PVAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYAS  352

Query  357  KDVSLLKREPLREFLENKNKTLDVFDGKKTYVSLKRLGIEAESIDFDLLLVSYLLNNTDN  416
             D+SLL  +++++ ++   K +  +D K++ V L +LGIE  +  +D  L +YLL+  ++
Sbjct  353  TDLSLLATDSFKQVFQ---KPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED  409

Query  417  SNDLGQLCQKQGYFGVKSDDEVYGKGAKKEICADETFFEHLRSKVFAIAFLKQKLMQKLK  476
             N+L+ + +    +++  DD VYGKGAK+ +   + ++EHL  KV  +   K ++++KL 
Sbjct  410  -NELSTIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLT  468

Query  477  DNSQDHLYFEIERPLSIVLAKMEIAGIKADKETLETMGSRFKEKISDLESLIYQEAGETF  536
             + Q +LY +IE PL+ VLAKMEI GIK ++ TL+ M+ + K  I  L   IY+ AG+ F
Sbjct  469  AHEQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEF  528

Query  537  NINSPKQLGMILFDKLGLP--GAKKTKTGYSTAVGVLEKLRG-NDIVDNVLLYRQFAKLK  593
            NINSPKQLG ILF+K+ LP   +KKTKTGYSTAV+VLE+L     IV ++L YRQ++KL+
Sbjct  529  NINSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQ  588

Query  594  STYIDGLIKVMDQDEKVHtrytqtltttGRLSSVEPNLQNIPVRLEEGRKIRQAFIPSHQ  653
            STY+ GL   +  D K+HTRY Q LT TGRLSSV+PNLQNIP+RLE+GR IR+AF PSH+
Sbjct  589  STYVIGLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHE  648

Query  654  GWEIFSSDYSQIELRVLAHISKDENMQKAFKDDFDIHANTAMKIFGLSSPDEVTPNMRRQ  713
            +  ++SSDYSQIELRVLAHIS DE++  AF+++ DIH++TAM++FG+  + +VT+N RR+
Sbjct  649  DAVLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRN  708

Query  714  AKAVNFGIVYGISDFGLAQSIGCRRDQAKTFMETYFESFPGVKRYMTEIVELARNQGYVE  773
            AKAVNFGIVYGISDFGL++++G  R Q+K++++TYFE +PG+K YM ++V  A+++GYVE
Sbjct  709  AKAVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVE  768

Query  774  TLFKRRRYLEGIRSKNFNQRSFAERTAMNTPIQGSAADIIKVAMIKMQETLEKEELKARM  833
            TLFKRRR L +I S+NFN RSFAERTA+N+PIQGSAADI+K+AMI+++ +L+   ++A+M
Sbjct  769  TLFKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKM  828

Query  834  LLQVHDELIFEAPEEEIPVLEKLVPSVMDSAVKLDVPLKVESGHGKTWFDTK  885
            LLQVHDE+++E P++E+  + KLV   M++AV L VPL V+ + G++W+++K
Sbjct  829  LLQVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

199) polA in NC_015278


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  750 bits (2838),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 466/896 (53%), Positives = 665/896 (75%), Gaps = 24/896 (2%)

Query  1    MSKQEKLLLFDGSSLAFRAFFAM-HDLNRFKNNKGLHTNALYAFHLMLTHVLEKEKPSHA  59
            M +++KLLL+DGSS+AFRAFFA+ ++++RFKN+ GLHTNA+Y+FHLML H++ + +P+H 
Sbjct  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60

Query  60   LVAWDAGKTTFRTAYYPEYKGGRDKTPQEFVEQMPYFNKLLDAFGIAHYELANYEADDII  119
            LVA DAGKTTFRT  Y++YK+GR KTP+EF EQ +Y+  +L A+GIA YEL +YEADDII
Sbjct  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120

Query  120  GTLSQRG--AEAGMDVVIISGDKDLIQLARDQVRVDINRKGVTNIDSYTPQSIQADQGIS  177
            GTL + +  +E   DV I+SGDKDLIQL+ ++  V+I++KGV++++ +TP  +    G++
Sbjct  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180

Query  178  PEQLIDVKGLMGDNSDNYPGVTGIGEKTALKLVQEFGSMEEVYANIDQVSGKKRKENLVK  237
            P+Q+ID+K+LMGD+SDN PGVT IGEKT+LKL++EFGS+E +Y +ID     K KENL++
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  238  DKDQAFLSKKLARIILDAPVEKSLADLKCQGIQAQDLVNFYREMNFKQFMEKFLANSGAD  297
            D+DQAFLSK LA I   +P+  +L D+  +G +   L +FY EM+F Q + K LA+    
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQ-LKKGLAS----  295

Query  298  ADFELEDSSWEVPDYQVLDQLEAKHFTQDQTALYLEMFENNYHEGKLIYVVWGNKDHIYL  357
               ++ + +  V  YQ + ++ A  F+ ++  +Y+E + +NYH   +I   WG+ ++IY 
Sbjct  296  ---QMPQEPVAVISYQEVTNVSADLFSAEDI-FYFETLRDNYHREAIIGFAWGHGEQIY-  350

Query  358  ASPDL-VRESQAFKNWIEDPHAKKVLYDAKRSQVILKGLGMDLEGVSDDVLIASYLIHAR  416
            AS DL +  +++FK+ ++ P A    YD KRS+V+L  LG++L + S D  +A+YL+ + 
Sbjct  351  ASTDLSLLATDSFKQVFQKPIAT---YDFKRSKVLLSHLGIELVAPSYDARLANYLLSTV  407

Query  417  DLSGDVANVAREFNLDYLAYDSEVYGKGKKVAVPEDKTRLYDHLVAKVSVINDLLPIIKD  476
            +   +++ +AR F    L  D  VYGKG K AVP DK  L +HL  KV V+ D  + + D
Sbjct  408  E-DNELSTIARIFTDISLEEDDTVYGKGAKRAVP-DKDVLLEHLARKVKVLLDSKSQMLD  465

Query  477  RLEADEMVELYRKIELPLAQVLAKMEIMGISVDRSRLVGLSQSYEEQLDQLQEEIYREAG  536
            +L A+E ++LY++IELPLA+VLAKMEI GI V+R+ L ++++     ++ L +EIY  AG
Sbjct  466  KLTAHEQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAG  525

Query  537  VEFNINSTQQLSKVLFEDM--GLKGGKKTKSGNYSTAQSELEKLQGV-PIIDLILAYRQL  593
             EFNINS +QL+ +LFE M   L   KKTK+G YSTA   LE+L  + PI+  IL YRQ+
Sbjct  526  QEFNINSPKQLGSILFEKMQLPLEMTKKTKTG-YSTAVDVLERLAPIAPIVAKILDYRQI  584

Query  594  AKLQSTYVQGILDYIHQDGKVHSRFIQTLTTTGRLSSADPNLQNIPIRTEEGRKIRQAFV  653
            +KLQSTYV G+ DYI  DGK+H+R++Q LT TGRLSS DPNLQNIPIR E+GR IR+AF 
Sbjct  585  TKLQSTYVIGLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFT  644

Query  654  PSHPDWVIFSSDYSQIELRVLAHVSGDPHLQEAFKENKDIHTATAAKVFHKD-EKDISKD  712
            PSH D V++SSDYSQIELRVLAH+SGD HL  AF+E  DIHT+TA +VF  D   D++ +
Sbjct  645  PSHEDAVLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTAN  704

Query  713  ERRQAKAVNFGIVYGISDYGLSQNLSISRQEAKAFIDKYFEIYPKVAEYMDKSVEIAREA  772
            +RR+AKAVNFGIVYGISD+GLS+NL+I+R+++K++ID YFE YP +  YM++ V  A++ 
Sbjct  705  DRRNAKAVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDK  764

Query  773  GYAKTLFNRRRYLPDLKAKNYNVRSFAERTAMNSPIQGTAADIIKVAMVEMDQALKEHQL  832
            GY  TLF+RRR LPD++++N+NVRSFAERTA+NSPIQG+AADI+K+AM+++D+AL+   +
Sbjct  765  GYVETLFKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGF  824

Query  833  QANLLLQVHDELIFEVAKEDLEDLAALVKDVMENAVSLDVPLIVDSNYGSTWYDAK  888
            +A++LLQVHDE+++EV++++L  +  LVKD ME AV L VPL VD + G +WY+AK
Sbjct  825  RAKMLLQVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

200) polA in NC_011567


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  744 bits (2815),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 456/885 (52%), Positives = 657/885 (75%), Gaps = 21/885 (2%)

Query  3    NKLVLIDGNSIAYRAFFAL----PLLHNDKGIHTNAIYGFTMMLMKLIEEEKPTHILVAF  58
            NKL+LIDG+S+A+RAFFAL      + N+ G+HTNAIYGF +ML  ++   +PTH+LVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  59   DAGKTTFRHEVYTEYKGGRQKTPPELSEQFPFLRELLDAYNIRTYELENYEADDIIGTLA  118
            DAGKTTFR E+Y++YK+GR KTP E+ EQF+++RE+L A  I  YELE+YEADDIIGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  119  TKAEKEG--FDVVIISGDRDLTQLASERIHVHVTKKGITDMERYTPKHVLEKYGLTPAQI  176
              AE+    FDV I+SGD+DL QL+ E   V+++KKG+++ E +TP  ++EK GLTP Q+
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  177  VDLKGLMGDASDNIPGVPGVGEKTALKLLKEYGTVEHVLASLEHISGKKLKENLQTYHEQ  236
            +DLK+LMGD SDNIPGV  +GEKT+LKLL E+G++E +   ++ +   K+KENL   ++Q
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRDQ  244

Query  237  ALLSKQLATIRRDVPLTLSLDELAWHSYDAERVAALFQELGFTSLMDKIGQSSQEQLSLT  296
            A+LSK LATI    P+T++LD++  ++ D   ++ +++E++F  L   ++    ++ +++
Sbjct  245  AFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQE-PVA  303

Query  297  DISFVTVQTIDEHMLTKEGALVVEVLDENYHQAPIVGFALVNERGHFFIPTDIAL-ASSR  355
             IS+  V  +  ++++ E+ +  E L +NYH+ +I+GFA  +   +++ +TD++L A+  
Sbjct  304  VISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHG-EQIYASTDLSLLATDS  362

Query  356  FKRWLEDEQCKKSVFDAKRAIVALKWNGIELKGVDFDLLLAAYLLNPTDANGDVAAVAKT  415
            FK+ ++      + +D KR+ V L   GIEL +  +D  LA YLL+  + + +++++A+ 
Sbjct  363  FKQVFQKP---IATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVE-DNELSTIARI  418

Query  416  KQYTDV--QSDEEVYGKGAKQAIPPTNVLAEHLVRKAKAIASLKETYIQELKRNEQFELL  473
              +TD+  + D+ VYGKGAK+A+P  +VL EHL RK K +   K   ++ L  +EQ++L 
Sbjct  419  --FTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLY  476

Query  474  VHLELPLTFILAQMEFYGVKVDVDRLEQMGKEFTAQLEQIEQRIYELAGTTFNINSPKQL  533
             ++ELPL+ +LA+ME+ G+KV+   L++M+ +    +E + Q IY++AG  FNINSPKQL
Sbjct  477  QNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQL  536

Query  534  GTILFEKLQLP--IVKKTKTGYSTSADVLEKLAPYHEIIEQILHYRQLGKLQSTYVEGLM  591
            G+ILFEK+QLP  + KKTKTGYST+ DVLE+LAP   I+ +IL+YRQ+ KLQSTYV GL 
Sbjct  537  GSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQ  596

Query  592  KVVRKDTGKVHTIFQQALTQTGRLSSTEPNLQNIPIRIEEGRKIRQAFVPSSDDWVIFAA  651
              +  D GK+HT + Q LTQTGRLSS +PNLQNIPIR+E+GR IR+AF PS +D V++++
Sbjct  597  DYILAD-GKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSS  655

Query  652  DYSQIELRVLAHIANDENLIAAFHHDLDIHTKTAMDIFHV-KEDEVTAHMRRQAKAVNFG  710
            DYSQIELRVLAHI+ DE+LIAAF+++ DIHT TAM +F + K  +VTA+ RR+AKAVNFG
Sbjct  656  DYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFG  715

Query  711  IVYGISDYGLSQNLGITRKEAAEFIERYFRSYPGVKRYMEEVVQDAKQKGYVTTLLHRRR  770
            IVYGISD+GLS+NLGITRK++  +I+ YF  YPG+K YME+VV++AK+KGYV TL+ RRR
Sbjct  716  IVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRR  775

Query  771  YLPDITSGNFNVRSFAERTAMNTPIQGSAADIIKKAMIDLANRLHEERLQTRLLLQVHDE  830
             LPDI S NFNVRSFAERTA+N+PIQGSAADI+K AMI+L + L+   +++++LLQVHDE
Sbjct  776  ELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDE  835

Query  831  LILEAPKEEIELLKKIVPDVMENAVSLRVPLKVDYHFGPTWYDAK  875
            ++LE P++E+  +KK+V D ME AV L VPL VD   G +WY+AK
Sbjct  836  IVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

201) C270_03045 in NC_018673


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  743 bits (2811),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 462/896 (52%), Positives = 662/896 (74%), Gaps = 25/896 (2%)

Query  3    KKLLLIDGNSLAFRAFYAMYQQLDRMISHNGLHTNALVAFNNFLDQIVDPMQPDLALVAW  62
            +KLLLIDG+S+AFRAF+A+Y+Q+DR  +H+GLHTNA+ +F+  LD+++  ++P   LVA 
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  63   DAGSGKDTYRGQLFPEYKDGRSKTPSEFKEQFPYLREMVALHGLRNYEKIGLEADDIIGT  122
            DAG  K T+R +++++YK GR+KTP EF+EQF+Y+REM++  G+  YE    EADDIIGT
Sbjct  65   DAG--KTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGT  122

Query  123  YSRMGE--AAGYSVTIITGDQDLIQLATDNITVNVTKKGVTELERYTPAYIMEKYGLTPQ  180
              +M+E     + VTI++GD+DLIQL+ +N  V+++KKGV+E+E +TPAY+MEK GLTP+
Sbjct  123  LDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPN  182

Query  181  QIIEKKALTGDTSDNYPGVTKVGEKTALKLLAEYENIDNLYANIEDMKKSKMKENLINDR  240
            Q+I+ KAL GD SDN PGVTK+GEKT+LKLL E+ +++ +Y +I++ K SKMKENLINDR
Sbjct  183  QFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDR  242

Query  241  ESAFRARKLATISTDATLDLPLQEIEYRGIDYDKLVLFYQDLDFKQQLAKIKALRKSGQI  300
            + AF ++ LATI+T + + + L++I Y G D   L  FY+++DF Q       L+K    
Sbjct  243  DQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQ-------LKK----  291

Query  301  AGGDEQNETQVHVVTLTDTNLRAVTMLGKKVAVHIETTGDNYHIDEMIGFVIGNPEVGYY  360
            + + +  +  V V++  +    +  +++      +ET  DNYH + +IGF  G+ E   Y
Sbjct  292  GLASQMPQEPVAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGE-QIY  350

Query  361  ASRDMTLLQTTELKSIIEDENVVKNVFNVKAQLILFKRLGLQLKGTYFDFLLAAYLLDTT  420
            AS D++LL T  +K +++        ++ K   +L+ +LG++L +  +D  LA YLL T 
Sbjct  351  ASTDLSLLATDSFKQVFQKPI---ATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTV  407

Query  421  DNDNELSTLAQRF-DVYMSSDDEIYGKGAKFAVPDDEGRVLMHLAHKADTLMQLELPALA  479
            + DNELST+A+ F D+ +  DD +YGKGAK AVPD +  +L HLA+K   L++     L 
Sbjct  408  E-DNELSTIARIFTDISLEEDDTVYGKGAKRAVPDKDV-LLEHLARKVKVLLDSKSQMLD  465

Query  480  ALKAHEQMHLYTEIELPLAHVLADMEYQGIRINQTRLYDMGVDLQGRIHTIEDAIYIEAG  539
             L AHEQ++LY +IELPLA+VLA ME +GI++N++ L DM+ + +  I+++ + IY  AG
Sbjct  466  KLTAHEQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAG  525

Query  540  EKFNINSPKQLGILLFEKMGLP--VIKKTKTGYSTAVDVLEKLASQAPIVDHILQYRQLA  597
            + FNINSPKQLG +LFEKM LP  + KKTKTGYSTAVDVLE+LA+ APIV  IL+YRQ++
Sbjct  526  QEFNINSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQIT  585

Query  598  KLKSTYIDGMLSVVYPQDSKIHTRFLQTLTQTGRLSSVDPNLQNIPMRTEEGRLIRKAFV  657
            KL+STY+ G+   + + D+KIHTR++Q LTQTGRLSSVDPNLQNIP+R E+GRLIRKAF 
Sbjct  586  KLQSTYVIGLQDYILA-DGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFT  644

Query  658  PSEPNWQIFGADYSQIELRVLAHITGDKNMQKAFLNGEDIHAETARAVFGLADDTPVDAN  717
            PS+ +  ++++DYSQIELRVLAHI+GD ++  AF +G DIH+ TA  VFG+   + V AN
Sbjct  645  PSHEDAVLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTAN  704

Query  718  MRRTAKAVNFGIVYGISDFGLANNLGISRAEAKQFIDTYFKEFPQIHEWMDKIKQSAHEL  777
             RR AKAVNFGIVYGISDFGL+NNLGI+R ++K +IDTYF  +P I   M+++ + A + 
Sbjct  705  DRRNAKAVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDK  764

Query  778  GFVETIAKRRRYLPNIQSKNFNLRSFAERTAMNSPIQGSAADIIKIAMIKVNSALKENNL  837
            G+VET+ KRRR LP+I+S+NFN+RSFAERTA+NSPIQGSAADI+KIAMI+++ AL+   +
Sbjct  765  GYVETLFKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGF  824

Query  838  QARMLLQVHDELIFEAPSNEISELSELVTSVMDSAVSLDVPMKVDNHYGDTWYDAK  893
            +A+MLLQVHDE+++E P++E++ +  LV   M++AV L VP+ VD+  G++WY+AK
Sbjct  825  RAKMLLQVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

202) Geoth_0907 in NC_015660


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  742 bits (2806),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 463/886 (53%), Positives = 649/886 (74%), Gaps = 19/886 (2%)

Query  3    KRKLVLIDGNSVAYRAFFAL----PLLHNDKGIHTNAVYGFTMMLMKILEEEKPTHMLVA  58
            K KL+LIDG+SVA+RAFFAL      + N+ G+HTNA+YGF +ML  ++   +PTH+LVA
Sbjct  4    KNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVA  63

Query  59   FDAGKTTFRHKTFEEYKGGRQKTPPELSEQFPLLRELLNAYQIRFYELENYEADDIIGTL  118
            FDAGKTTFR   + +YK+GR KTP E+ EQF+ +RE+L A  I +YELE+YEADDIIGTL
Sbjct  64   FDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTL  123

Query  119  CAKAENEG--FEVKVISGDRDLTQLVSDHVTVDITKKGITDVESYTPETVREKYGLAPQQ  176
               AE     F+V ++SGD+DL QL  ++  V+I+KKG+++ E +TP  + EK GL+P+Q
Sbjct  124  DKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQ  183

Query  177  IIDLKGLMGDKSDNIPGVPGIGEKTALKLLKEFGSIENILDSIEQISGNKLKENLEKHRD  236
            +IDLK+LMGDKSDNIPGV  IGEKT+LKLL EFGS+E I + I+ +  +K+KENL ++RD
Sbjct  184  FIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRD  243

Query  237  LALMSKQLATILRDAPIDLSFEDIEYRGYDVDKVIALFKELSFNSLLGKMAPQEEEKTAV  296
             A++SK LATI   +PI ++++DI Y G DV  +  ++ E+ F  L   +A+Q  +    
Sbjct  244  QAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQE---  300

Query  297  ALPEIGYKIVDEVTEAILSDEAALVVEVLESNYHKAPILGFAIANEHGNFFIRTD-TALS  355
            +++ I+Y+ V +V+  ++S E  +  E L  NYH+ +I+GFA ++ + +++  TD + L+
Sbjct  301  PVAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGE-QIYASTDLSLLA  359

Query  356  SSLFTTWLEDESKKKSVFDGKRAIVSLKWQGVHLRGIQFDLLIASYLLNPSQSTEDVASI  415
            +  F   ++   K  + +D KR+ V L   G++L +  +D  +A+YLL+  +  +++++I
Sbjct  360  TDSFKQVFQ---KPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NELSTI  415

Query  416  AKTKQYVGVQSDEAVYGKGAKQKVPDEQVLAEHLVRKAAAIRALEQGFIHDLQENEQYSL  475
            A+    ++++ D++VYGKGAK+ VPD +VL EHL RK   +       ++ L  +EQ  L
Sbjct  416  ARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDL  475

Query  476  FTDLELPLSTILAEMEFAGVKVDVERLKEMGEELAEQLKEVEQEIYRLAGQEFNINSPKQ  535
            + ++ELPL+ +LA ME+ G+KV+   L++M+E+    +  + QEIY +AGQEFNINSPKQ
Sbjct  476  YQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQ  535

Query  536  LGVILFEKLQLP--VLKKTKTGYSTSAEVLEKLAPQHEIVEKILHYRQLGKLQSTYIEGL  593
            LG ILFEK+QLP  + KKTKTGYST+ +VLE+LAP   IV KIL+YRQ+ KLQSTY+ GL
Sbjct  536  LGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGL  595

Query  594  LKVVHRDTNKVHTIFNQALTQTGRLSSTEPNLQNIPIRLEEGRKIRQAFIPSEPDWVIFS  653
               +  D  K+HT + Q LTQTGRLSS +PNLQNIPIRLE+GR IR+AF PS+ D V++S
Sbjct  596  QDYILAD-GKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLS  654

Query  654  ADYSQIELRVLAHIANDENLIDAFRHGLDIHTKTAMDIFHVSKE-EVTPNMRRQAKAVNF  712
            +DYSQIELRVLAHI+ DE+LI AF +G DIHT TAM +F + K  +VT+N RR+AKAVNF
Sbjct  655  SDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNF  714

Query  713  GIVYGISDYGLSQNLNITRKEAAEFIKRYFEIFPGVKQYMKDIVQEAKQKGYVTTLLHRR  772
            GIVYGISD+GLS+NL ITRK++  +I  YFE +PG+K YM ++V+EAK+KGYV TL+ RR
Sbjct  715  GIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRR  774

Query  773  RYLPDITSRNFNLRSFAERTAMNTPIQGSAADIIKKAMIDLSKRLQKENMKARMLLQVHD  832
            R LPDI SRNFN+RSFAERTA+N+PIQGSAADI+K AMI+L K LQ    +A+MLLQVHD
Sbjct  775  RELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHD  834

Query  833  ELILEAPKDEIERLQQIVPEVMENAVQLRVPLKVDYHFGPTWYDAK  878
            E++LE P+DE+  ++++V + ME AV+L VPL VD   G +WY+AK
Sbjct  835  EIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

203) Bcer98_3272 in NC_009674


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  742 bits (2807),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 450/885 (51%), Positives = 667/885 (76%), Gaps = 19/885 (2%)

Query  3    KKVVLVDGNNIAYRAFFAL----PLLNNDKGIHTNAIYGFTMMLMRILEEEKPTHMLVAF  58
            +K++L+DG+++A+RAFFAL      ++N+ G+HTNAIYGF +ML +++   +PTH+LVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  59   DAGKTTFRHKTFSDYKGGRQKTPPELSEQFPFIRELLDAFRVPRYELEDYEADDIMGTLA  118
            DAGKTTFR   ++DYK+GR KTP E+ EQF++IRE+L A+ ++ YELE+YEADDI+GTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  119  K--EASEQGAQVKVISGDKDLLQLVSDHTRVCIPRKGITEVDEYTKEALFEKYNLSPKQI  176
            K  E +E   +V ++SGDKDL+QL  ++T V I++KG++E +E+T   L EK  L+P+Q+
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  177  IDMKGLMGDQSDNIPGVPGVGEKTAIKLLTQFGTVEAVYENLDQVSGkklkekleTHKEQ  236
            ID+K+LMGD+SDNIPGV  +GEKT++KLL +FG++E++YE++D     K+KE+L  +++Q
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRDQ  244

Query  237  AFMSKELATIITDAPITVHIDDIEYKGYEAGDIIPLFENLGFTSLLNKLGAP-SEEAVSA  295
            AF+SK LATI T +PIT+ +DDI Y+G + + +  ++++++F  L + L++  ++E+V+ 
Sbjct  245  AFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEPVAV  304

Query  296  ELDDISFEIAEEVTEEMLQQDSAIIVEVQEENYHKADIQGFGIQNDNGCYFIPTDIALAS  355
                IS++   +V+ +++  +  +  E   +NYH+  I GF+  +++  Y  +TD++L +
Sbjct  305  ----ISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIY-ASTDLSLLA  359

Query  356  EAFIKWLKDEEMRKYTFDAKRAIVALKWKGVEIRGVDFDLLIAAYLLDPADTDKDFRTVA  415
               +K + +  +  Y F  KR+ V L   G+E+ +  +D  +A YLL   + D+++ T+A
Sbjct  360  TDSFKQVFQKPIATYDF--KRSKVLLSHLGIELVAPSYDARLANYLLSTVE-DNELSTIA  416

Query  416  KMKETHAVKSDEEVYGKGAKRAVPAQEIVAEHVARKVHVLYDVKQTFIDELEKNEQYELF  475
            ++    ++  D+ VYGKGAKRAVP ++++ EH+ARKV VL D K   +D L  +EQ +L+
Sbjct  417  RIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLY  476

Query  476  INLEMPLACVLADMEVKGVKVDTERLRNMGDELAGRLKEMEQEIYELAGTEFNINSPKQL  535
             N+E+PLA VLA ME+ G+KV+   L++M+++    +  + QEIY++AG EFNINSPKQL
Sbjct  477  QNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQL  536

Query  536  GVVLFEKLNLPV--IKKTKTGYSTSADVLDKLMDHHEIIPKILHYRQLGKLNSTYIEGLL  593
            G +LFEK++LP+   KKTKTGYST+ DVL++L     I++KIL+YRQ+ KL+STY+ GL 
Sbjct  537  GSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQ  596

Query  594  KVVHDESSKIHTRFNQVLTQTGRLSSTEPNLQNIPIRLEEGRKIRQAFIPSQEGWVMYAA  653
              +  ++ KIHTR+ Q LTQTGRLSS +PNLQNIPIRLE+GR IR+AF PS+E+ V+ ++
Sbjct  597  DYILADG-KIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSS  655

Query  654  DYSQIELRVLAHIAKDKGLIEAFQHDMDIHTKTAMDVFGVEKD-EVTANMRRQAKAVNFG  712
            DYSQIELRVLAHI+ D  LI AF+++ DIHT TAM VFG++K  +VTAN RR+AKAVNFG
Sbjct  656  DYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFG  715

Query  713  IVYGISDYGLSQNLGITRKAAGEFIEKYFASFPGVKEYMDEIVQEAKQKGYVSTLLNRRR  772
            IVYGISD+GLS+NLGITRK +  +I+ YF  +PG+K YM+++V+EAK+KGYV TL++RRR
Sbjct  716  IVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRR  775

Query  773  YIPEITSRNFNVRSFAERTAMNTPIQGSAADIIKKAMIVMADRLEEEGLQARLLLQVHDE  832
             +P+I SRNFNVRSFAERTA+N+PIQGSAADI+K AMI +   L+  G++A++LLQVHDE
Sbjct  776  ELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDE  835

Query  833  LIFEVPKEEIEKLEKLVPEVMEHAIELAVPLKVDYSYGPTWYDAK  877
            +++EVP++E+  + KLV + ME A++LAVPL VD S G +WY+AK
Sbjct  836  IVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

204) GY4MC1_0838 in NC_014650


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  741 bits (2803),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 463/886 (53%), Positives = 647/886 (74%), Gaps = 19/886 (2%)

Query  3    KRKLVLIDGNSVAYRAFFAL----PLLHNDKGIHTNAVYGFTMMLMKILEEEKPTHMLVA  58
            K KL+LIDG+SVA+RAFFAL      + N+ G+HTNA+YGF +ML  ++   +PTH+LVA
Sbjct  4    KNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVA  63

Query  59   FDAGKTTFRHKTFEEYKGGRQKTPPELSEQFPLLRELLNAYQIRFYELENYEADDIIGTL  118
            FDAGKTTFR   + +YK+GR KTP E+ EQF+ +RE+L A  I +YELE+YEADDIIGTL
Sbjct  64   FDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTL  123

Query  119  CAKAENEG--FEVKVISGDRDLTQLVSDHVTVDITKKGITDVESYTPETVREKYGLAPQQ  176
               AE     F+V ++SGD+DL QL  ++  V+I+KKG+++ E +TP  + EK GL+P+Q
Sbjct  124  DKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQ  183

Query  177  IIDLKGLMGDKSDNIPGVPGIGEKTALKLLKEFGSIENILDSIEQISGNKLKENLEKHRD  236
            +IDLK+LMGDKSDNIPGV  IGEKT+LKLL EFGS+E I + I+ +  +K+KENL ++RD
Sbjct  184  FIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRD  243

Query  237  LALMSKQLATILRDAPIDLSFEDIEYRGYDVDKVIALFKELSFNSLLDKMAPQEEEKTAV  296
             A++SK LATI   +PI ++++DI Y G DV  +  ++ E+ F  L   +A+Q  +    
Sbjct  244  QAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQE---  300

Query  297  ALPKIRYEIVDEVTEAILSDEAALVVEVLESNYHKAPILGFAIANEHGNFFIRTD-TALS  355
            +++ I Y+ V +V+  ++S E  +  E L  NYH+ +I+GFA ++ + +++  TD + L+
Sbjct  301  PVAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGE-QIYASTDLSLLA  359

Query  356  SSLFTTWLEDESKKKSVFDGKRAIVSLKWQGVHLRGIQFDLLIASYLLNPSQSTEDVASI  415
            +  F   ++   K  + +D KR+ V L   G++L +  +D  +A+YLL+  +  +++++I
Sbjct  360  TDSFKQVFQ---KPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NELSTI  415

Query  416  AKTKQYAGVQSDEAVYGKGAKQKVPDEQVLAEHLVRKAAAIRALEQGFIHDLQENEQYSL  475
            A+     +++ D++VYGKGAK+ VPD +VL EHL RK   +       ++ L  +EQ  L
Sbjct  416  ARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDL  475

Query  476  FTDLELPLSTILAEMEFAGVKVDVERLKEMGEELAEQLKEVEQEIYRLAGQEFNINSPKQ  535
            + ++ELPL+ +LA ME+ G+KV+   L++M+E+    +  + QEIY +AGQEFNINSPKQ
Sbjct  476  YQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQ  535

Query  536  LGVILFEKLQLP--VLKKTKTGYSTSAEVLEKLAPQHEIVEKILHYRQLGKLQSTYIEGL  593
            LG ILFEK+QLP  + KKTKTGYST+ +VLE+LAP   IV KIL+YRQ+ KLQSTY+ GL
Sbjct  536  LGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGL  595

Query  594  LKVVHRDTNKVHTIFNQALTQTGRLSSTEPNLQNIPIRLEEGRKIRQAFIPSEPDWVIFS  653
               +  D  K+HT + Q LTQTGRLSS +PNLQNIPIRLE+GR IR+AF PS+ D V++S
Sbjct  596  QDYILAD-GKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLS  654

Query  654  ADYSQIELRVLAHIANDENLIDAFRHGLDIHTKTAMDIFHVSKE-EVTPNMRRQAKAVNF  712
            +DYSQIELRVLAHI+ DE+LI AF +G DIHT TAM +F + K  +VT+N RR+AKAVNF
Sbjct  655  SDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNF  714

Query  713  GIVYGISDYGLSQNLNITRKEAAEFIKRYFEIFPGVKQYMKDIVQEAKQKGYVTTLLHRR  772
            GIVYGISD+GLS+NL ITRK++  +I  YFE +PG+K YM ++V+EAK+KGYV TL+ RR
Sbjct  715  GIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRR  774

Query  773  RYLPDITSRNFNLRSFAERTAMNTPIQGSAADIIKKAMIDLSKRLQKENMKARMLLQVHD  832
            R LPDI SRNFN+RSFAERTA+N+PIQGSAADI+K AMI+L K LQ    +A+MLLQVHD
Sbjct  775  RELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHD  834

Query  833  ELILEAPKDEIERLQQIVPEVMENAVQLRVPLKVDYHFGPTWYDAK  878
            E++LE P+DE+  ++++V + ME AV+L VPL VD   G +WY+AK
Sbjct  835  EIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

205) GWCH70_2673 in NC_012793


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  738 bits (2793),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 458/889 (52%), Positives = 651/889 (74%), Gaps = 24/889 (2%)

Query  2    KKKLVLIDGNSIAYRAFFAL----PLLHNDKGIHTNAVYGFTMMLMKILEEEKPTHMLVA  57
            K+KL+LIDG+S+A+RAFFAL      + N+ G+HTNA+YGF +ML  ++   +PTH+LVA
Sbjct  4    KNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVA  63

Query  58   FDAGKTTFRHKTFEEYKGGRQQTPPELSEQFPLLRELLDAYRIRFYELENYEADDIIGTL  117
            FDAGKTTFR   + +YK+GR +TP E+ EQF+ +RE+L A  I +YELE+YEADDIIGTL
Sbjct  64   FDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTL  123

Query  118  CTKAEKEG--FEVKVISGDRDLTQLASDHVTVDITKKGITDVESYTPETVQEKYGLTPEQ  175
               AE+    F+V ++SGD+DL QL+ ++  V+I+KKG+++ E +TP  + EK GLTP+Q
Sbjct  124  DKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQ  183

Query  176  IIDLKGLMGDKSDNIPGVPGIGEKTALKLLKEFGTIENILDSIEQVSGNKLRENLAKYRD  235
            +IDLK+LMGDKSDNIPGV  IGEKT+LKLL EFG++E I + I+    +K++ENL + RD
Sbjct  184  FIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRD  243

Query  236  IALMSKQLATILRDAPVDLSLEDIEYNGYDVDKVIALFKELGFNSLLEKMAAPQGEEETE  295
             A++SK LATI   +P+ ++L+DI YNG DV  +  ++ E++F  L   +A+   +E   
Sbjct  244  QAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEPVA  303

Query  296  VALSDIDYTIVDEVTESILSDEAALVVEVLESNYHKAPILGFAIANEHGNFFIRTD-TAL  354
            V    I Y  V +V+  ++S E  +  E L  NYH+ +I+GFA ++ + +++  TD + L
Sbjct  304  V----ISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGE-QIYASTDLSLL  358

Query  355  SSSLFTQWLEDESKKKSVFDGKRAIVSLKWQGIQLRGVQFDLLIASYLLNPSQSTEDVAS  414
            ++  F Q ++   K  + +D KR+ V L   GI+L +  +D  +A+YLL+  +  +++++
Sbjct  359  ATDSFKQVFQ---KPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NELST  414

Query  415  IAKTKQYTDV--QSDEAIYGKGAKQKIPDEPVLAEHLVRKAAAIRALEQDFICDLQENEQ  472
            IA+   +TD+  + D+++YGKGAK+ +PD  VL EHL RK   +     + +  L  +EQ
Sbjct  415  IARI--FTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQ  472

Query  473  YSLFTDLELPLSSILAEMEFTGVKIDVKRLKEMGEELTEQLKEIEQEIYELAGQEFNINS  532
              L+ ++ELPL+++LA ME+ G+K++   L++M+E+    +  + QEIY++AGQEFNINS
Sbjct  473  LDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINS  532

Query  533  PKQLGVILFEKLQLP--VLKKTKTGYSTSAEVLEKLAPQHEIVEKILHYRQLGKLQSTYI  590
            PKQLG ILFEK+QLP  + KKTKTGYST+ +VLE+LAP   IV KIL+YRQ+ KLQSTY+
Sbjct  533  PKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYV  592

Query  591  EGLLKVVHHDTNKVHTIFNQALTQTGRLSSTEPNLQNIPIRLEEGRKIRQAFVPSEPDWV  650
             GL   +  D  K+HT + Q LTQTGRLSS +PNLQNIPIRLE+GR IR+AF PS+ D V
Sbjct  593  IGLQDYILAD-GKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAV  651

Query  651  IFSADYSQIELRVLAHIANDENLIDAFRHDLDIHTKTAMDIFHVN-EDEVTPNMRRQAKA  709
            ++S+DYSQIELRVLAHI+ DE+LI AF ++ DIHT TAM +F ++   +VT+N RR+AKA
Sbjct  652  LLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKA  711

Query  710  VNFGIVYGISDYGLSQNLNITRKEASEFIKRYFEIFPGVKQYMKDIVQEAKQKGYVTTLL  769
            VNFGIVYGISD+GLS+NL ITRK++  +I  YFE +PG+K YM ++V+EAK+KGYV TL+
Sbjct  712  VNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLF  771

Query  770  HRRRYLPDITSRNFNLRSFAERTAMNTPIQGSAADIIKKAMIDLSNRLKKENMKARMLLQ  829
             RRR LPDI SRNFN+RSFAERTA+N+PIQGSAADI+K AMI+L + L+    +A+MLLQ
Sbjct  772  KRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQ  831

Query  830  VHDELILEAPKEEVERLQQIVPEVMENAVQLRVPLKVDYHFGPTWYDAK  878
            VHDE++LE P++E+  ++++V + ME AV+L VPL VD   G +WY+AK
Sbjct  832  VHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

206) SSIL_1198 in NC_018065


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  735 bits (2779),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 439/884 (50%), Positives = 660/884 (75%), Gaps = 15/884 (1%)

Query  2    TKQKLLLLDGNSLAYRAFFAL----PLLTNDSGIHTNATYGFTTMLQKIIGEENPTQMLV  57
             K+KLLL+DG+S+A+RAFFAL      + N+SG+HTNA YGF  ML+ ++    PT++LV
Sbjct  3    NKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLV  62

Query  58   AFDAGKTTFRHESFGEYKGGRQKTPPELSEQFPYIRKLIDAYNIKRYELEMYEADDIIGT  117
            AFDAGKTTFR E +++YK+GR KTP E+ EQF+YIR ++ A  I  YELE YEADDIIGT
Sbjct  63   AFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGT  122

Query  118  LAKQAAGQGI--EVIVVSGDKDLTQLATEDVTVYITRKGITDIEKYTPAHIEEKYGLTPE  175
            L K A    +  +V +VSGDKDL QL+ E+  V I++KG++++E +TPA + EK GLTP+
Sbjct  123  LDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPN  182

Query  176  QIIDMKGLMGDQSDNIPGVPGVGEKTAIKLLKEHGTIEKLYEEMDSLKASKMKEKLVDNE  235
            Q+ID+K+LMGD+SDNIPGV  +GEKT++KLL E G++E +YE++D++K+SKMKE+L+++ 
Sbjct  183  QFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDR  242

Query  236  EMAHLSKKLATIHTDAPLTISLDDLAYAGPDEEALLNVWQELGFKSLIEKSDFEAVETEQ  295
            + A LSK LATI+T +P+TI+LDD+ Y GPD  +L +  +E++F  L      +  +   
Sbjct  243  DQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEPV  302

Query  296  AELVFENVQAITGDMLKETMAIHLELENEHYHSCNALGLALSDGERTVYTAID-NVVDNA  354
            A + +++V  +++D++     + +E   ++YH    +G+A ++GE+ +Y++ D +++   
Sbjct  303  AVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQ-IYASTDLSLLATD  361

Query  355  DLKAWLQDETKKKYIVDSKATQAMLHRLGIELKGVEFDLLLASYILKPSISGDDVATLAK  414
             +K  +Q      Y  D K ++ +L +LGIEL +  +D  LA+Y+L +++ +++++T+A+
Sbjct  362  SFKQVFQKPIAT-Y--DFKRSKVLLSHLGIELVAPSYDARLANYLL-STVEDNELSTIAR  417

Query  415  EFGYQDVQSNEAIYGKGAKWVVPGADHVAEHVSRKAVAVWKLQPLLDQKLKENEQFELYK  474
             F    ++ ++++YGKGAK+ VP+ D + EH++RK   +   ++ + +KL  +EQ++LY+
Sbjct  418  IFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQ  477

Query  475  ELELPLAHILGKMESEGITVNIDTLRQMGDDLKAKLEVMEATIYELAGEKFNINSPKQLG  534
            ++ELPLA++L+KME EGI VN  TL++M+++ K  +E +   IY++AG+ FNINSPKQLG
Sbjct  478  NIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLG  537

Query  535  VILFDKLGLP--VIKKTKTGYSTAADVLEKLQSEHDIVKYILEYRTLAKLQSTYIEGLIK  592
             ILF+K+ LP  + KKTKTGYSTA DVLE+L +   IV  IL+YR ++KLQSTY+ GL +
Sbjct  538  SILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGL-Q  596

Query  593  EVHKEDSKVHTRFQQALTSTGRLSSTNPNLQNIPIRLEEGRKIRKAFVPSKKDWILFAAD  652
            +    D+K+HTR+ Q LT TGRLSS +PNLQNIPIRLE+GR IRKAF PS  D +L+++D
Sbjct  597  DYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSD  656

Query  653  YSQIELRVLAHMCGDEALVEAFQQGMDIHTRTAMDVFNLENPDEVTSLMRRTAKAVNFGI  712
            YSQIELRVLAH+ GDE L+ AF++G DIHT TAM VF ++++ +VT+  RR AKAVNFGI
Sbjct  657  YSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGI  716

Query  713  VYGISDYGLSQSLDITRKEAAIFIENYLQSFPGVKNYMDTSIEEAKKAGFVTTILNRRRY  772
            VYGISD+GLS++L+ITRK++  +I+ Y++ +PG+K YM+  + EAK  G+V T+++RRR 
Sbjct  717  VYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRE  776

Query  773  LPDITSSNFNLRSFAERTAMNTPIQGSAADIIKKAMIDMNARLEQEGLQTKLLLQVHDEL  832
            LPDI S NFN+RSFAERTA+N+PIQGSAADI+K AMI+++  L+  G+++K+LLQVHDE+
Sbjct  777  LPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEI  836

Query  833  IFEAPKEEIEILERIVPEVMENAIKLSVPLKVEFSYGATWYDAK  876
            ++E P++E+  + ++V + ME A+ L+VPL V+ S G +WY+AK
Sbjct  837  VLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

207) polA in NC_018704


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  734 bits (2777),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 452/890 (51%), Positives = 642/890 (73%), Gaps = 20/890 (2%)

Query  1    MTDKQKLILIDGNSILYRAFFAL----PLLSNDKGVYTNAVFGFTKMLMKVLEEESPSHI  56
            M +K+KL+LIDG+S+ +RAFFAL      + N+ G+ TNA++GF  ML  ++    P+H+
Sbjct  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60

Query  57   MIAFDAGKTTFRHAKYKDYKGGRQKTPPELSEQFLLVRELLDASSIVHYELEQYEADDII  116
            ++AFDAGKTTFR   Y DYK+GR KTP E+ EQF  +RE+L A +I  YELE+YEADDII
Sbjct  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120

Query  117  GTLAKKAAQAN--FNVQVITGDKDMLQLVSEDVHVQITRKGISELDIYTPEFLEEKLTIK  174
            GTL K A +++  F+V +++GDKD++QL  E+  V+I++KG++E++ +TP +L EK+ + 
Sbjct  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180

Query  175  PEQVIDMKALMGDSSDNIPGVTGVGEKTAIKLLNQFGTLENIYQNLDQVSGKKLKENLTN  234
            P+Q ID+KALMGD SDNIPGVT +GEKT++KLL++FG+LE IY+++D     K+KENL N
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  235  QKDLAFLSKELVTINQDSPVEIELDQIAYKGYDQSRLTALFKDLGFKsllssldgessde  294
            ++D AFLSK L TIN  SP+ I LD+I Y+G D + L+ ++ +++F          +   
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDF-----VQLKKGLAS  295

Query  295  seQTETLSPIDLKIISSFDEVKLTGTDAFTVEILEENYHTGEIIGFGLANDQGNYFIPTD  354
                E ++ I  + +++     +++ D F  E L +NYH   IIGF+ ++++  Y  +TD
Sbjct  296  QMPQEPVAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIY-ASTD  354

Query  355  VAL-GSDQFKQWLEGSTKKKITFDAKKVMVSLRRYGIQVKGIIFDLLLASYLINPAENSH  413
            ++L ++D FKQ ++   K   T+D K+  V L + GI++ +  +D  LA+YL++  E+ +
Sbjct  355  LSLLATDSFKQVFQ---KPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-N  410

Query  414  DIPAISHRLGYQNLLFDEEVYGKGAKMSVPEQAIVADHVVRKAKALFQLQKDAEAKLQEN  473
            ++++I++ +   +L  D+ VYGKGAK +VP++ ++ +H+ RK K L++ + +   KL  +
Sbjct  411  ELSTIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAH  470

Query  474  EQESLFKELELPLASILADMESTGVKVDEKQLEVMQSELKARLSAIETEIHEQAGVAFNI  533
            EQ  L++++ELPLA++LA ME  G+KV+   L+ M  + K  + A+  EI + AG  FNI
Sbjct  471  EQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNI  530

Query  534  NSPKQLSEILFEKLNLP--VIKKTKTGYSTSADVLEKLEDKHPIIPSILLYRQLGKLQST  591
            NSPKQL+ ILFEK++LP  + KKTKTGYST+ DVLE+L    PI++ IL YRQ+ KLQST
Sbjct  531  NSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQST  590

Query  592  YIEGLLKVIHDDKKIHTRFNQALTQTGRLSSVDPNLQNIPIRLEEGRKIRKAFIPSENDW  651
            Y+ GL   I  D KIHTR+ Q LTQTGRLSSVDPNLQNIPIRLE+GR IRKAF PS++D 
Sbjct  591  YVIGLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDA  650

Query  652  IILAFDYSQIELRVLAHIANDEKLIEAFKSDRDIHTQTAMDVFNV-TADEVDSLMRRQAK  710
            ++L+ DYSQIELRVLAHI+ DE LI AF+ + DIHT TAM VF +  A +V +  RR+AK
Sbjct  651  VLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAK  710

Query  711  AVNFGIVYGISDYGLSQNLKITRKEAQAFIDQYFVSYPGVKQYMDDIVHKAKLDGYVTTL  770
            AVNFGIVYGISD+GLS+NL ITRK+++++ID YF  YPG+K YM+++V+ AK  GYV TL
Sbjct  711  AVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETL  770

Query  771  MNRRRYLPEITSRNFNQRSFAERTAMNTPIQGSAADIIKKAMIDLDHALKAGNFEARLLL  830
             +RRR LP+I SRNFN RSFAERTA+N+PIQGSAADI+K AMI+LD AL+AG F A++LL
Sbjct  771  FKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLL  830

Query  831  QVHDELIIEAPREEADKLLELVPKVMTETVTLNVPLKVDASQGESWYDAK  880
            QVHDE+++E P +E   +  LV   M  +V L VPL VD S G+SWY+AK
Sbjct  831  QVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

208) polA in NC_012472


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  734 bits (2775),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 446/885 (51%), Positives = 663/885 (75%), Gaps = 19/885 (2%)

Query  3    KKVVLVDGNNIAYRAFFAL----PLLNNDKGIHTNAIYGFTMMLMRILEEEKPTHMLVAF  58
            +K++L+DG+++A+RAFFAL      ++N+ G+HTNAIYGF +ML +++   +PTH+LVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  59   DAGKTTFRHKTYSEYKGGRQKTPPELSEQFPFIREMLDAFNVPRYELENYEADDIMGTLA  118
            DAGKTTFR   Y++YK+GR KTP E+ EQF++IREML A+ ++ YELE+YEADDI+GTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  119  K--EASEQGASVKVISGDKDLLQLVSDNTLVCIPRKGITEVDEYTKEALFEKYSLSPKQI  176
            K  E +E    V ++SGDKDL+QL  +NT+V I++KG++E +E+T   L EK +L+P+Q+
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  177  IDMKGLMGDQSDNIPGVPGVGEKTAIKLLTQFGTVEEVYENIDQVSGKKLKEKLEANKDQ  236
            ID+K+LMGD+SDNIPGV  +GEKT++KLL +FG++E +YE+ID     K+KE+L  ++DQ
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRDQ  244

Query  237  ALMSKDLATIITDAPITVNVDDMEYKGYEASDVIPMFENLGFTSLLNKLGVTPEETAPAE  296
            A++SK LATI T +PIT+ +DD+ Y+G + + +   +++++F  L + L+    + +   
Sbjct  245  AFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLA---SQMPQEP  301

Query  297  LDDITFDIVEEVTEEMLQQDSALIVEVQEDNYHKADIQGFGIQNENGCYFIQTDIAL-KS  355
            +  I+++ V +V+ +++  +  +  E   DNYH+  I GF+  + +  Y   TD++L  +
Sbjct  302  VAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIY-ASTDLSLLAT  360

Query  356  DAFKEWLADGEMRKYTFDAKRAIVALKWNGIDMQGIDFDLLIAAYLLDPADTDKDFRTVA  415
            D+FK+ + +  +  Y F  KR+ V L   GI++ +  +D  +A YLL   + D+++ T+A
Sbjct  361  DSFKQ-VFQKPIATYDF--KRSKVLLSHLGIELVAPSYDARLANYLLSTVE-DNELSTIA  416

Query  416  KMKETHAVKSDEEVYGKGAKRAVPELEIVAEHVARKVHVLYDVKQTFVEELEKNEQYELF  475
            ++    ++  D+ VYGKGAKRAVP+ +++ EH+ARKV VL D K   ++ L  +EQ +L+
Sbjct  417  RIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLY  476

Query  476  TELELPLARVLADMEVKGVKVDTERLRNMGEELAGRLKEMEQEIYKLAGTEFNINSPKQL  535
             ++ELPLA VLA ME+ G+KV+   L++M+E+    +  + QEIY +AG EFNINSPKQL
Sbjct  477  QNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQL  536

Query  536  GVILFENLNLP--VIKKTKTGYSTSADVLDKLMDHHEIIPNILHYRQLGKLNSTYIEGLL  593
            G ILFE+++LP  + KKTKTGYST+ DVL++L     I+++IL+YRQ+ KL+STY+ GL 
Sbjct  537  GSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQ  596

Query  594  KVVHEDSSKIHTRFNQVLTQTGRLSSTDPNLQNIPIRLEEGRKIRQAFVPSEEGWIMYAA  653
              +  D+ KIHTR+ Q LTQTGRLSS DPNLQNIPIRLE+GR IR+AF PS+E+ ++ ++
Sbjct  597  DYILADG-KIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSS  655

Query  654  DYSQIELRVLAHIANDKGLVEAFKHDMDIHTKTAMDVFGVEKD-EVTSNMRRQAKAVNFG  712
            DYSQIELRVLAHI+ D  L+ AF+++ DIHT TAM VFG++K  +VT+N RR+AKAVNFG
Sbjct  656  DYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFG  715

Query  713  IVYGISDYGLSQNLGITRKAAAEFIEKYLESFPGVQEYMDDIVKDAKQKGYVATLLNRRR  772
            IVYGISD+GLS+NLGITRK +  +I+ Y+E +PG++ YM+++V++AK+KGYV TL++RRR
Sbjct  716  IVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRR  775

Query  773  YIPEITSRNFNLRSFAERTAMNTPIQGTaadiikkamiimadRLEEEGLQARLLLQVHDE  832
             +P+I SRNFN+RSFAERTA+N+PIQG+AADI+K AMI +   L+  G++A++LLQVHDE
Sbjct  776  ELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDE  835

Query  833  LIFEAPKEEIEKLEKLVPEVMEHAIELAVPLKVDYSYGPTWYDAK  877
            +++E P++E+  + KLV + ME A++LAVPL VD S G +WY+AK
Sbjct  836  IVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

209) bcf_22975 in NC_016779


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  734 bits (2775),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 446/885 (51%), Positives = 663/885 (75%), Gaps = 19/885 (2%)

Query  3    KKVVLVDGNNIAYRAFFAL----PLLNNDKGIHTNAIYGFTMMLMRILEEEKPTHMLVAF  58
            +K++L+DG+++A+RAFFAL      ++N+ G+HTNAIYGF +ML +++   +PTH+LVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  59   DAGKTTFRHKTYSEYKGGRQKTPPELSEQFPFIREMLDAFNVPRYELENYEADDIMGTLA  118
            DAGKTTFR   Y++YK+GR KTP E+ EQF++IREML A+ ++ YELE+YEADDI+GTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  119  K--EASEQGASVKVISGDKDLLQLVSDNTLVCIPRKGITEVDEYTKEALFEKYSLSPKQI  176
            K  E +E    V ++SGDKDL+QL  +NT+V I++KG++E +E+T   L EK +L+P+Q+
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  177  IDMKGLMGDQSDNIPGVPGVGEKTAIKLLTQFGTVEEVYENIDQVSGKKLKEKLEANKDQ  236
            ID+K+LMGD+SDNIPGV  +GEKT++KLL +FG++E +YE+ID     K+KE+L  ++DQ
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRDQ  244

Query  237  ALMSKDLATIITDAPITVNVDDMEYKGYEASDVIPMFENLGFTSLLNKLGVTPEETAPAE  296
            A++SK LATI T +PIT+ +DD+ Y+G + + +   +++++F  L + L+    + +   
Sbjct  245  AFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLA---SQMPQEP  301

Query  297  LDDITFDIVEEVTEEMLQQDSALIVEVQEDNYHKADIQGFGIQNENGCYFIQTDIAL-KS  355
            +  I+++ V +V+ +++  +  +  E   DNYH+  I GF+  + +  Y   TD++L  +
Sbjct  302  VAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIY-ASTDLSLLAT  360

Query  356  DAFKEWLADGEMRKYTFDAKRAIVALKWNGIDMQGIDFDLLIAAYLLDPADTDKDFRTVA  415
            D+FK+ + +  +  Y F  KR+ V L   GI++ +  +D  +A YLL   + D+++ T+A
Sbjct  361  DSFKQ-VFQKPIATYDF--KRSKVLLSHLGIELVAPSYDARLANYLLSTVE-DNELSTIA  416

Query  416  KMKETHAVKSDEEVYGKGAKRAVPELEIVAEHVARKVHVLYDVKQTFVEELEKNEQYELF  475
            ++    ++  D+ VYGKGAKRAVP+ +++ EH+ARKV VL D K   ++ L  +EQ +L+
Sbjct  417  RIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLY  476

Query  476  TELELPLARVLADMEVKGVKVDTERLRNMGEELAGRLKEMEQEIYKLAGTEFNINSPKQL  535
             ++ELPLA VLA ME+ G+KV+   L++M+E+    +  + QEIY +AG EFNINSPKQL
Sbjct  477  QNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQL  536

Query  536  GVILFENLNLP--VIKKTKTGYSTSADVLDKLMDHHEIIPNILHYRQLGKLNSTYIEGLL  593
            G ILFE+++LP  + KKTKTGYST+ DVL++L     I+++IL+YRQ+ KL+STY+ GL 
Sbjct  537  GSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQ  596

Query  594  KVVHEDSSKIHTRFNQVLTQTGRLSSTDPNLQNIPIRLEEGRKIRQAFVPSEEGWIMYAA  653
              +  D+ KIHTR+ Q LTQTGRLSS DPNLQNIPIRLE+GR IR+AF PS+E+ ++ ++
Sbjct  597  DYILADG-KIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSS  655

Query  654  DYSQIELRVLAHIANDKGLVEAFKHDMDIHTKTAMDVFGVEKD-EVTSNMRRQAKAVNFG  712
            DYSQIELRVLAHI+ D  L+ AF+++ DIHT TAM VFG++K  +VT+N RR+AKAVNFG
Sbjct  656  DYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFG  715

Query  713  IVYGISDYGLSQNLGITRKAAAEFIEKYLESFPGVQEYMDDIVKDAKQKGYVATLLNRRR  772
            IVYGISD+GLS+NLGITRK +  +I+ Y+E +PG++ YM+++V++AK+KGYV TL++RRR
Sbjct  716  IVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRR  775

Query  773  YIPEITSRNFNLRSFAERTAMNTPIQGTaadiikkamiimadRLEEEGLQARLLLQVHDE  832
             +P+I SRNFN+RSFAERTA+N+PIQG+AADI+K AMI +   L+  G++A++LLQVHDE
Sbjct  776  ELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDE  835

Query  833  LIFEAPKEEIEKLEKLVPEVMEHAIELAVPLKVDYSYGPTWYDAK  877
            +++E P++E+  + KLV + ME A++LAVPL VD S G +WY+AK
Sbjct  836  IVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

210) polA in NC_008600


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  734 bits (2776),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 446/885 (51%), Positives = 663/885 (75%), Gaps = 19/885 (2%)

Query  17   KKVVLVDGNNIAYRAFFAL----PLLNNDKGIHTNAIYGFTMMLMRILEEEKPTHMLVAF  72
            +K++L+DG+++A+RAFFAL      ++N+ G+HTNAIYGF +ML +++   +PTH+LVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  73   DAGKTTFRHKTYSEYKGGRQKTPPELSEQFPFIREMLDAFNVPRYELENYEADDIMGTLA  132
            DAGKTTFR   Y++YK+GR KTP E+ EQF++IREML A+ ++ YELE+YEADDI+GTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  133  K--EASEQGASVKVISGDKDLLQLVSDNTLVCIPRKGITEVDEYTKEALFEKYSLSPKQI  190
            K  E +E    V ++SGDKDL+QL  +NT+V I++KG++E +E+T   L EK +L+P+Q+
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  191  IDMKGLMGDQSDNIPGVPGVGEKTAIKLLTQFGTVEEVYENIDQVSGKKLKEKLEANKDQ  250
            ID+K+LMGD+SDNIPGV  +GEKT++KLL +FG++E +YE+ID     K+KE+L  ++DQ
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRDQ  244

Query  251  ALMSKDLATIITDAPITVNVDDMEYKGYEASDVIPMFENLGFTSLLNKLGVTPEETAPAE  310
            A++SK LATI T +PIT+ +DD+ Y+G + + +   +++++F  L + L+    + +   
Sbjct  245  AFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLA---SQMPQEP  301

Query  311  LDDITFDIVEEVTEEMLQQDSALIVEVQEDNYHKADIQGFGIQNENGCYFIQTDIAL-KS  369
            +  I+++ V +V+ +++  +  +  E   DNYH+  I GF+  + +  Y   TD++L  +
Sbjct  302  VAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIY-ASTDLSLLAT  360

Query  370  DAFKEWLADGEMRKYTFDAKRAIVALKWNGIDMQGIDFDLLIAAYLLDPADTDKDFRTVA  429
            D+FK+ + +  +  Y F  KR+ V L   GI++ +  +D  +A YLL   + D+++ T+A
Sbjct  361  DSFKQ-VFQKPIATYDF--KRSKVLLSHLGIELVAPSYDARLANYLLSTVE-DNELSTIA  416

Query  430  KMKETHAVKSDEEVYGKGAKRAVPELEIVAEHVARKVHVLYDVKQTFVEELEKNEQYELF  489
            ++    ++  D+ VYGKGAKRAVP+ +++ EH+ARKV VL D K   ++ L  +EQ +L+
Sbjct  417  RIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLY  476

Query  490  TELELPLARVLADMEVKGVKVDTERLRNMGEELAGRLKEMEQEIYKLAGTEFNINSPKQL  549
             ++ELPLA VLA ME+ G+KV+   L++M+E+    +  + QEIY +AG EFNINSPKQL
Sbjct  477  QNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQL  536

Query  550  GVILFENLNLP--VIKKTKTGYSTSADVLDKLMDHHEIIPNILHYRQLGKLNSTYIEGLL  607
            G ILFE+++LP  + KKTKTGYST+ DVL++L     I+++IL+YRQ+ KL+STY+ GL 
Sbjct  537  GSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQ  596

Query  608  KVVHEDSSKIHTRFNQVLTQTGRLSSTDPNLQNIPIRLEEGRKIRQAFVPSEEGWIMYAA  667
              +  D+ KIHTR+ Q LTQTGRLSS DPNLQNIPIRLE+GR IR+AF PS+E+ ++ ++
Sbjct  597  DYILADG-KIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSS  655

Query  668  DYSQIELRVLAHIANDKGLVEAFKHDMDIHTKTAMDVFGVEKD-EVTSNMRRQAKAVNFG  726
            DYSQIELRVLAHI+ D  L+ AF+++ DIHT TAM VFG++K  +VT+N RR+AKAVNFG
Sbjct  656  DYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFG  715

Query  727  IVYGISDYGLSQNLGITRKAAAEFIEKYLESFPGVQEYMDDIVKDAKQKGYVATLLNRRR  786
            IVYGISD+GLS+NLGITRK +  +I+ Y+E +PG++ YM+++V++AK+KGYV TL++RRR
Sbjct  716  IVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRR  775

Query  787  YIPEITSRNFNLRSFAERTAMNTPIQGTaadiikkamiimadRLEEEGLQARLLLQVHDE  846
             +P+I SRNFN+RSFAERTA+N+PIQG+AADI+K AMI +   L+  G++A++LLQVHDE
Sbjct  776  ELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDE  835

Query  847  LIFEAPKEEIEKLEKLVPEVMEHAIELAVPLKVDYSYGPTWYDAK  891
            +++E P++E+  + KLV + ME A++LAVPL VD S G +WY+AK
Sbjct  836  IVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

211) polA in NC_006274


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  733 bits (2774),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 446/885 (51%), Positives = 663/885 (75%), Gaps = 19/885 (2%)

Query  17   KKVVLVDGNNIAYRAFFAL----PLLNNDKGIHTNAIYGFTMMLMRILEEEKPTHMLVAF  72
            +K++L+DG+++A+RAFFAL      ++N+ G+HTNAIYGF +ML +++   +PTH+LVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  73   DAGKTTFRHKTYSEYKGGRQKTPPELSEQFPFIREMLDAFNVPRYELENYEADDIMGTLA  132
            DAGKTTFR   Y++YK+GR KTP E+ EQF++IREML A+ ++ YELE+YEADDI+GTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  133  K--EASEQGASVKVISGDKDLLQLVSDNTLVCIPRKGITEVDEYTEEALFEKYSLSPKQI  190
            K  E +E    V ++SGDKDL+QL  +NT+V I++KG++E +E+T   L EK +L+P+Q+
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  191  IDMKGLMGDQSDNIPGVPGVGEKTAIKLLTQFGTVEEVYENIDQVSGKKLKEKLEANKDQ  250
            ID+K+LMGD+SDNIPGV  +GEKT++KLL +FG++E +YE+ID     K+KE+L  ++DQ
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRDQ  244

Query  251  ALMSKDLATIITDAPITVNVDDMEYKGYEASDVIPMFENLGFTSLLNKLGVTPEETAPAE  310
            A++SK LATI T +PIT+ +DD+ Y+G + + +   +++++F  L + L+    + +   
Sbjct  245  AFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLA---SQMPQEP  301

Query  311  LDDITFDIVEEVTEEMLQQDSALIVEVQEDNYHKADIQGFGIQNENGCYFIQTDIAL-KS  369
            +  I+++ V +V+ +++  +  +  E   DNYH+  I GF+  + +  Y   TD++L  +
Sbjct  302  VAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIY-ASTDLSLLAT  360

Query  370  DAFKEWLADGEMRKYTFDAKRAIVALKWNGIDMQGIDFDLLIAAYLLDPADTDKDFRTVA  429
            D+FK+ + +  +  Y F  KR+ V L   GI++ +  +D  +A YLL   + D+++ T+A
Sbjct  361  DSFKQ-VFQKPIATYDF--KRSKVLLSHLGIELVAPSYDARLANYLLSTVE-DNELSTIA  416

Query  430  KMKETHAVKSDEEVYGKGAKRAVPELEIVAEHVARKVHVLYDVKQTFVEELEKNEQYELF  489
            ++    ++  D+ VYGKGAKRAVP+ +++ EH+ARKV VL D K   ++ L  +EQ +L+
Sbjct  417  RIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLY  476

Query  490  TELELPLARVLADMEVKGVKVDTERLRNMGEELAGRLKEMEQEIYKLAGTEFNINSPKQL  549
             ++ELPLA VLA ME+ G+KV+   L++M+E+    +  + QEIY +AG EFNINSPKQL
Sbjct  477  QNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQL  536

Query  550  GVILFENLNLP--VIKKTKTGYSTSADVLDKLMDHHEIIPNILHYRQLGKLNSTYIEGLL  607
            G ILFE+++LP  + KKTKTGYST+ DVL++L     I+++IL+YRQ+ KL+STY+ GL 
Sbjct  537  GSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQ  596

Query  608  KVVHEDSSKIHTRFNQVLTQTGRLSSTDPNLQNIPIRLEEGRKIRQAFVPSEEGWIMYAA  667
              +  D+ KIHTR+ Q LTQTGRLSS DPNLQNIPIRLE+GR IR+AF PS+E+ ++ ++
Sbjct  597  DYILADG-KIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSS  655

Query  668  DYSQIELRVLAHIANDKGLVEAFQHDMDIHTKTAMDVFGVEKD-EVTSNMRRQAKAVNFG  726
            DYSQIELRVLAHI+ D  L+ AF+++ DIHT TAM VFG++K  +VT+N RR+AKAVNFG
Sbjct  656  DYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFG  715

Query  727  IVYGISDYGLSQNLGITRKAAAEFIEKYLESFPGVQEYMDDIVKDAKQKGYVATLLNRRR  786
            IVYGISD+GLS+NLGITRK +  +I+ Y+E +PG++ YM+++V++AK+KGYV TL++RRR
Sbjct  716  IVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRR  775

Query  787  YIPEITSRNFNLRSFAERTAMNTPIQGTaadiikkamiimadRLEEEGLQARLLLQVHDE  846
             +P+I SRNFN+RSFAERTA+N+PIQG+AADI+K AMI +   L+  G++A++LLQVHDE
Sbjct  776  ELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDE  835

Query  847  LIFEAPKEEIEKLEKLVPEVMEHAIELAVPLKVDYSYGPTWYDAK  891
            +++E P++E+  + KLV + ME A++LAVPL VD S G +WY+AK
Sbjct  836  IVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

212) polA in NC_005957


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  733 bits (2774),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 446/885 (51%), Positives = 663/885 (75%), Gaps = 19/885 (2%)

Query  17   KKVVLVDGNNIAYRAFFAL----PLLNNDKGIHTNAIYGFTMMLMRILEEEKPTHMLVAF  72
            +K++L+DG+++A+RAFFAL      ++N+ G+HTNAIYGF +ML +++   +PTH+LVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  73   DAGKTTFRHKTYSEYKGGRQKTPPELSEQFPFIREMLDAFNVPRYELENYEADDIMGTLA  132
            DAGKTTFR   Y++YK+GR KTP E+ EQF++IREML A+ ++ YELE+YEADDI+GTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  133  K--EASEQGASVKVISGDKDLLQLVSDNTLVCIPRKGITEVDEYTKEALFEKYSLSPKQI  190
            K  E +E    V ++SGDKDL+QL  +NT+V I++KG++E +E+T   L EK +L+P+Q+
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  191  IDMKGLMGDQSDNIPGVPGVGEKTAIKLLTQFGTVEEVYENIDQVSGKKLKEKLEANKDQ  250
            ID+K+LMGD+SDNIPGV  +GEKT++KLL +FG++E +YE+ID     K+KE+L  ++DQ
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRDQ  244

Query  251  ALMSKDLATIITDAPITVNVDDMEYKGYEASDVIPMFENLGFTSLLNKLGVTPEETAPAE  310
            A++SK LATI T +PIT+ +DD+ Y+G + + +   +++++F  L + L+    + +   
Sbjct  245  AFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLA---SQMPQEP  301

Query  311  LDDITFDIVEEVTEEMLQQDSALIVEVQEDNYHKADIQGFGIQNENGCYFIQTDIAL-KS  369
            +  I+++ V +V+ +++  +  +  E   DNYH+  I GF+  + +  Y   TD++L  +
Sbjct  302  VAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIY-ASTDLSLLAT  360

Query  370  DAFKEWLADGEMRKYTFDAKRAIVALKWNGIDMQGIDFDLLIAAYLLDPADTDKDFRTVA  429
            D+FK+ + +  +  Y F  KR+ V L   GI++ +  +D  +A YLL   + D+++ T+A
Sbjct  361  DSFKQ-VFQKPIATYDF--KRSKVLLSHLGIELVAPSYDARLANYLLSTVE-DNELSTIA  416

Query  430  KMKETHAVKSDEEVYGKGAKRAVPELEIVAEHVARKVHVLYDVKQTFVEELEKNEQYELF  489
            ++    ++  D+ VYGKGAKRAVP+ +++ EH+ARKV VL D K   ++ L  +EQ +L+
Sbjct  417  RIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLY  476

Query  490  TELELPLARVLADMEVKGVKVDTERLRNMGEELAGRLKEMEQEIYKLAGTEFNINSPKQL  549
             ++ELPLA VLA ME+ G+KV+   L++M+E+    +  + QEIY +AG EFNINSPKQL
Sbjct  477  QNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQL  536

Query  550  GVILFENLNLP--VIKKTKTGYSTSADVLDKLMDHHEIIPNILHYRQLGKLNSTYIEGLL  607
            G ILFE+++LP  + KKTKTGYST+ DVL++L     I+++IL+YRQ+ KL+STY+ GL 
Sbjct  537  GSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQ  596

Query  608  KVVHEDSSKIHTRFNQVLTQTGRLSSTDPNLQNIPIRLEEGRKIRQAFVPSEEGWIMYAA  667
              +  D+ KIHTR+ Q LTQTGRLSS DPNLQNIPIRLE+GR IR+AF PS+E+ ++ ++
Sbjct  597  DYILADG-KIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSS  655

Query  668  DYSQIELRVLAHIANDKGLVEAFQHDMDIHTKTAMDVFGVEKD-EVTSNMRRQAKAVNFG  726
            DYSQIELRVLAHI+ D  L+ AF+++ DIHT TAM VFG++K  +VT+N RR+AKAVNFG
Sbjct  656  DYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFG  715

Query  727  IVYGISDYGLSQNLGITRKAAAEFIEKYLESFPGVQEYMDDIVKDAKQKGYVATLLNRRR  786
            IVYGISD+GLS+NLGITRK +  +I+ Y+E +PG++ YM+++V++AK+KGYV TL++RRR
Sbjct  716  IVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRR  775

Query  787  YIPEITSRNFNLRSFAERTAMNTPIQGTaadiikkamiimadRLEEEGLQARLLLQVHDE  846
             +P+I SRNFN+RSFAERTA+N+PIQG+AADI+K AMI +   L+  G++A++LLQVHDE
Sbjct  776  ELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDE  835

Query  847  LIFEAPKEEIEKLEKLVPEVMEHAIELAVPLKVDYSYGPTWYDAK  891
            +++E P++E+  + KLV + ME A++LAVPL VD S G +WY+AK
Sbjct  836  IVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

213) polA in NC_011969


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  732 bits (2769),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 445/884 (51%), Positives = 660/884 (75%), Gaps = 17/884 (1%)

Query  17   KKVVLVDGNNIAYRAFFAL----PLLNNDKGIHTNAIYGFTMMLMRILEEEKPTHMLVAF  72
            +K++L+DG+++A+RAFFAL      ++N+ G+HTNAIYGF +ML +++   +PTH+LVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  73   DAGKTTFRHKTYSEYKGGRQKTPPELSEQFPFIREMLDAFNVPRYELENYEADDIMGTLA  132
            DAGKTTFR   Y++YK+GR KTP E+ EQF++IREML A+ ++ YELE+YEADDI+GTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  133  K--EASEQGASVKVISGDKDLLQLVSDNTLVCIPRKGITEVDEYTKEALFEKYSLSPKQI  190
            K  E +E    V ++SGDKDL+QL  +NT+V I++KG++E +E+T   L EK +L+P+Q+
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  191  IDMKGLMGDQSDNIPGVPGVGEKTAIKLLTQFGTVEEVYENIDQVSGKKLKEKLEANKDQ  250
            ID+K+LMGD+SDNIPGV  +GEKT++KLL +FG++E +YE+ID     K+KE+L  ++DQ
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRDQ  244

Query  251  ALMSKDLATIITDAPITVHVDDMEYKGYEPSDVIPMFENLGFTSLLNKLGVTPEETAPAE  310
            A++SK LATI T +PIT+ +DD+ Y+G + + +   +++++F  L + L+    + +   
Sbjct  245  AFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLA---SQMPQEP  301

Query  311  LDDITFDIVEEVTEEMLQQDSALIVEVQEDNYHKADIQGFGIQNENGCYFIQTDSALKSD  370
            +  I+++ V +V+ +++  +  +  E   DNYH+  I GF+  + +  Y     S L +D
Sbjct  302  VAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLATD  361

Query  371  AFKEWLADGEMRKYTFDAKRAIVALKWNGIDMQGIDFDLLIAAYLLDPADTDKDFRTVAK  430
            +FK+ + +  +  Y F  KR+ V L   GI++ +  +D  +A YLL   + D+++ T+A+
Sbjct  362  SFKQ-VFQKPIATYDF--KRSKVLLSHLGIELVAPSYDARLANYLLSTVE-DNELSTIAR  417

Query  431  MKETHAVKSDEEVYGKGAKRAVPELEIVAEHVARKVHVLYDVKQTFVEELEKNEQYELFT  490
            +    ++  D+ VYGKGAKRAVP+ +++ EH+ARKV VL D K   ++ L  +EQ +L+ 
Sbjct  418  IFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQ  477

Query  491  ELELPLARVLADMEVKGVKVDTERLRNMGEELAGRLKEMEQEIYKLAGTEFNINSPKQLG  550
            ++ELPLA VLA ME+ G+KV+   L++M+E+    +  + QEIY +AG EFNINSPKQLG
Sbjct  478  NIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLG  537

Query  551  VILFENLNLP--VIKKTKTGYSTSADVLDKLMDHHEIIPNILHYRQLGKLNSTYIEGLLK  608
             ILFE+++LP  + KKTKTGYST+ DVL++L     I+++IL+YRQ+ KL+STY+ GL  
Sbjct  538  SILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQD  597

Query  609  VVHEDSSKIHTRFNQVLTQTGRLSSTDPNLQNIPIRLEEGRKIRQAFVPSEEGWIMYAAD  668
             +  D+ KIHTR+ Q LTQTGRLSS DPNLQNIPIRLE+GR IR+AF PS+E+ ++ ++D
Sbjct  598  YILADG-KIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSD  656

Query  669  YSQIELRVLAHIANDKGLVDAFQHDMDIHTKTAMDVFGVEKD-EVTSNMRRQAKAVNFGI  727
            YSQIELRVLAHI+ D  L+ AF+++ DIHT TAM VFG++K  +VT+N RR+AKAVNFGI
Sbjct  657  YSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGI  716

Query  728  VYGISDYGLSQNLGITRKAAAEFIEKYLESFPGVQEYMDDIVKDAKQKGYVATLLNRRRY  787
            VYGISD+GLS+NLGITRK +  +I+ Y+E +PG++ YM+++V++AK+KGYV TL++RRR 
Sbjct  717  VYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRE  776

Query  788  IPEITSRNFNLRSFAERTAMNTPIQGTaadiikkamiimadRLEEEGLQARLLLQVHDEL  847
            +P+I SRNFN+RSFAERTA+N+PIQG+AADI+K AMI +   L+  G++A++LLQVHDE+
Sbjct  777  LPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEI  836

Query  848  IFEAPKEEIEKLEKLVPEVMEHAIELAVPLKVDYSYGPTWYDAK  891
            ++E P++E+  + KLV + ME A++LAVPL VD S G +WY+AK
Sbjct  837  VLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

214) YBT020_22555 in NC_017200


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  732 bits (2769),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 446/885 (51%), Positives = 663/885 (75%), Gaps = 19/885 (2%)

Query  3    KKVVLVDGNNIAYRAFFAL----PLLNNDKGIHTNAIYGFTMMLMRILEEEKPTHMLVAF  58
            +K++L+DG+++A+RAFFAL      ++N+ G+HTNAIYGF +ML +++   +PTH+LVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  59   DAGKTTFRHKTYSEYKGGRQKTPPELSEQFPFIREMLDAFNVPRYELENYEADDIMGTLA  118
            DAGKTTFR   Y++YK+GR KTP E+ EQF++IREML A+ ++ YELE+YEADDI+GTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  119  K--EASEQGASVKVISGDKDLLQLVSDNTLVCIPRKGITEVDEYTKEALFEKYSLSPKQI  176
            K  E +E    V ++SGDKDL+QL  +NT+V I++KG++E +E+T   L EK +L+P+Q+
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  177  IDMKGLMGDQSDNIPGVPGVGEKTAIKLLTQFGTVEEVYENIDQVSGKKLKEKLEANKDQ  236
            ID+K+LMGD+SDNIPGV  +GEKT++KLL +FG++E +YE+ID     K+KE+L  ++DQ
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRDQ  244

Query  237  ALMSKDLATIITDAPITVHVDDMEYKGYEASDVIPMFENLGFTSLLNKLGVTPEETAPAE  296
            A++SK LATI T +PIT+ +DD+ Y+G + + +   +++++F  L + L+    + +   
Sbjct  245  AFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLA---SQMPQEP  301

Query  297  LDDITFDIVEEVTEEMLQQDSALIVEVQEDNYHKADIQGFGIQNENGCYFIQTDIAL-KS  355
            +  I+++ V +V+ +++  +  +  E   DNYH+  I GF+  + +  Y   TD++L  +
Sbjct  302  VAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIY-ASTDLSLLAT  360

Query  356  DAFKEWLADGEMRKYTFDAKRAIVALKWNGIDMQGIDFDLLIAAYLLDPADTDKDFRTVA  415
            D+FK+ + +  +  Y F  KR+ V L   GI++ +  +D  +A YLL   + D+++ T+A
Sbjct  361  DSFKQ-VFQKPIATYDF--KRSKVLLSHLGIELVAPSYDARLANYLLSTVE-DNELSTIA  416

Query  416  KMKETHAVKSDEEVYGKGAKRAVPELEIVAEHVARKVHVLYDVKQTFVEELEKNEQYELF  475
            ++    ++  D+ VYGKGAKRAVP+ +++ EH+ARKV VL D K   ++ L  +EQ +L+
Sbjct  417  RIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLY  476

Query  476  TELELPLARVLADMEVKGVKVDTERLRNMGEELAGRLKEMEQEIYKLAGTEFNINSPKQL  535
             ++ELPLA VLA ME+ G+KV+   L++M+E+    +  + QEIY +AG EFNINSPKQL
Sbjct  477  QNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQL  536

Query  536  GVILFENLNLP--VIKKTKTGYSTSADVLDKLMDHHEIIPNILHYRQLGKLNSTYIEGLL  593
            G ILFE+++LP  + KKTKTGYST+ DVL++L     I+++IL+YRQ+ KL+STY+ GL 
Sbjct  537  GSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQ  596

Query  594  KVVHEDSSKIHTRFNQVLTQTGRLSSTDPNLQNIPIRLEEGRKIRQAFVPSEEGWIMYAA  653
              +  D+ KIHTR+ Q LTQTGRLSS DPNLQNIPIRLE+GR IR+AF PS+E+ ++ ++
Sbjct  597  DYILADG-KIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSS  655

Query  654  DYSQIELRVLAHIANDKGLVEAFQHDMDIHTKTAMDVFGVEKD-EVTSNMRRQAKAVNFG  712
            DYSQIELRVLAHI+ D  L+ AF+++ DIHT TAM VFG++K  +VT+N RR+AKAVNFG
Sbjct  656  DYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFG  715

Query  713  IVYGISDYGLSQNLGITRKAAAEFIEKYLESFPGVQEYMDDIVKDAKQKGYVATLLNRRR  772
            IVYGISD+GLS+NLGITRK +  +I+ Y+E +PG++ YM+++V++AK+KGYV TL++RRR
Sbjct  716  IVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRR  775

Query  773  YIPEITSRNFNLRSFAERTAMNTPIQGTaadiikkamiimadRLEEEGLQARLLLQVHDE  832
             +P+I SRNFN+RSFAERTA+N+PIQG+AADI+K AMI +   L+  G++A++LLQVHDE
Sbjct  776  ELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDE  835

Query  833  LIFEAPKEEIEKLEKLVPEVMEHAIELAVPLKVDYSYGPTWYDAK  877
            +++E P++E+  + KLV + ME A++LAVPL VD S G +WY+AK
Sbjct  836  IVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

215) polA in NC_016605


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  731 bits (2765),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 474/886 (54%), Positives = 665/886 (76%), Gaps = 14/886 (1%)

Query  4    KRLLLIDGNSIAFRSFFALQNSLSRFTNADGLHTNAIYGFNKMLDIILDNVNPTDALVAF  63
            ++LLLIDG+S+AFR+FFAL N + RF N  GLHTNAIYGF+ MLD ++  V PT+ LVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  64   DAGKTTFRTKMYTNYKGGRAKTPSELTEQMPYLRDLLTGYGIKSYELADYEADDIIGTLS  123
            DAGKTTFRT MY++YK+GRAKTP E+ EQ +Y+R++LT+ GI  YEL +YEADDIIGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  124  LEAEK--LGYRVTIVTGDRDLTQLVSDkttvavtvkgvteveDYTPEHLKEKLGVTPTQV  181
              AE+  + + VTIV+GD+DL QL  ++T V ++ KGV+E E++TP  L EK+G+TP Q 
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  182  IDLKGLMGDSSDNYPGVTKVGEKTALKLIDQFGSVENLYDHIDDLKQSKMKEHLIEDEDN  241
            IDLK+LMGD SDN PGVTK+GEKT+LKL+++FGS+E +Y+HID++K SKMKE+LI+D D+
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRDQ  244

Query  242  AFLSKKLATIDRDSPLKIGLDQLEYKGINEEYLIDFYQKMGFKSYLKKFQKSGGLKEVEQ  301
            AFLSK LATI+  SP+ IGLD++ Y+G +   L +FY+ M+F    K +        V  
Sbjct  245  AFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEPVAV  304

Query  302  TQFQELTKANLDKAMESLGNEVSLYLEMPEKNYHLSSFAGFVIGNDEKWFVSRNVELLKL  361
              +QE+T+     + + ++ E  +Y+E    NYH  ++ GF  G++E+ + S ++ LL  
Sbjct  305  ISYQEVTNV----SADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLAT  360

Query  362  PTIKDLIENIDVKLNVFDSKRTYVGLNRLEINAQCFNYDVLLQSYLLDTNENSNDLGLLA  421
             ++K+++++    +  +D KR+ V L++L I+    +YD  L +YLL T E+ N+L+ +A
Sbjct  361  DSFKQVFQK---PIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NELSTIA  416

Query  422  QQHAYYNVESDADVYGTGAKLSIPDDDQTFFQHLANKGKAIEVLGKALDGELKQNEQDKL  481
            +  +  ++E D  VYG GAK ++PD D  +++HLA K K +      + + L  +EQ  L
Sbjct  417  RIFTDISLEEDDTVYGKGAKRAVPDKD-VLLEHLARKVKVLLDSKSQMLDKLTAHEQLDL  475

Query  482  YWEIELPLAIVLAKMEISGIRVDSNRLIQMQSEFAERLSEIEGEIYRLAGEEFNINSPKQ  541
            Y +IELPLA VLAKMEI GI+V+   L +M  +    +  +  EIY +AG+EFNINSPKQ
Sbjct  476  YQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQ  535

Query  542  LGRILFEKMRLP--IIKKTKTGYSTAVDVLEKLRGESDIVDDILNYRTISKIQSTYVEGL  599
            LG ILFEKM+LP  + KKTKTGYSTAVDVLE+L   + IV  IL+YR I+K+QSTYV GL
Sbjct  536  LGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGL  595

Query  600  LKVVHSKDQKIHTTYIQTLTQTGRLSSIEPNLQNIPVRIDEGKKIRQAFVPSKEGWHILS  659
               + + D KIHT Y+Q LTQTGRLSS++PNLQNIP+R+++G+ IR+AF PS E+  +LS
Sbjct  596  QDYILA-DGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLS  654

Query  660  SDYSQIELRVLAHLTGDKNMQEAFIENQDIHASTAVRIFGLKDASEVTPNIRRQAKAVNF  719
            SDYSQIELRVLAH++GD ++  AF E  DIH+STA+R+FG+  A++VT+N RR+AKAVNF
Sbjct  655  SDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNF  714

Query  720  GIVYGISDYGLSQNIGISRSDAKKFIETYFQEFPGVKNYVDNIVKVAKEQGYVETISHRR  779
            GIVYGISD+GLS+N+GI+R ++K +I+TYF+ +PG+K Y++N+V+ AK++GYVET+  RR
Sbjct  715  GIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRR  774

Query  780  RYLPDINSSNFSQRSFAERTAMNTPIQGSaadiikiamikmQQELESRNLKTKMLLQVHD  839
            R LPDINS NF+ RSFAERTA+N+PIQGSAADI+KIAMI++++ L++  +++KMLLQVHD
Sbjct  775  RELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHD  834

Query  840  ELIFEVPDEEMNEIKKLVPSVMDSAMKLKVPLKVETSWGNNWYEAK  885
            E+++EVP++E+  IKKLV   M++A+ L VPL V+ S G++WYEAK
Sbjct  835  EIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

216) polA in NC_011658


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  731 bits (2767),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 446/885 (51%), Positives = 663/885 (75%), Gaps = 19/885 (2%)

Query  3    KKVVLVDGNNIAYRAFFAL----PLLNNDKGIHTNAIYGFTMMLMRILEEEKPTHMLVAF  58
            +K++L+DG+++A+RAFFAL      ++N+ G+HTNAIYGF +ML +++   +PTH+LVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  59   DAGKTTFRHKTYSEYKGGRQKTPPELSEQFPFIREMLDAFNVPRYELENYEADDIMGTLA  118
            DAGKTTFR   Y++YK+GR KTP E+ EQF++IREML A+ ++ YELE+YEADDI+GTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  119  K--EASEQGASVKVISGDKDLLQLVSDNTLVCIPRKGITEVDEYTKEALFEKYSLSPKQI  176
            K  E +E    V ++SGDKDL+QL  +NT+V I++KG++E +E+T   L EK +L+P+Q+
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  177  IDMKGLMGDQSDNIPGVPGVGEKTAIKLLTQFGTVEEVYENIDQVSGKKLKEKLEANKDQ  236
            ID+K+LMGD+SDNIPGV  +GEKT++KLL +FG++E +YE+ID     K+KE+L  ++DQ
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRDQ  244

Query  237  ALMSKDLATIITDAPITVHVDDMEYKGYEPSDVIPMFENLGFTSLLNKLGVTPEETAPAE  296
            A++SK LATI T +PIT+ +DD+ Y+G + + +   +++++F  L + L+    + +   
Sbjct  245  AFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLA---SQMPQEP  301

Query  297  LDDITFDIVEEVTEEMLQQDSALIVEVQEDNYHKADIQGFGIQNENGCYFIQTDIAL-KS  355
            +  I+++ V +V+ +++  +  +  E   DNYH+  I GF+  + +  Y   TD++L  +
Sbjct  302  VAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIY-ASTDLSLLAT  360

Query  356  DAFKEWLADGEMRKYTFDAKRAIVALKWNGIDMQGIDFDLLIAAYLLDPADTDKDFRTVA  415
            D+FK+ + +  +  Y F  KR+ V L   GI++ +  +D  +A YLL   + D+++ T+A
Sbjct  361  DSFKQ-VFQKPIATYDF--KRSKVLLSHLGIELVAPSYDARLANYLLSTVE-DNELSTIA  416

Query  416  KMKETHAVKSDEEVYGKGAKRAVPELEIVAEHVARKVHVLYDVKQTFVEELEKNEQYELF  475
            ++    ++  D+ VYGKGAKRAVP+ +++ EH+ARKV VL D K   ++ L  +EQ +L+
Sbjct  417  RIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLY  476

Query  476  TELELPLARVLADMEVKGVKVDTERLRNMGEELAGRLKEMEQEIYKLAGTEFNINSPKQL  535
             ++ELPLA VLA ME+ G+KV+   L++M+E+    +  + QEIY +AG EFNINSPKQL
Sbjct  477  QNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQL  536

Query  536  GVILFENLNLP--VIKKTKTGYSTSADVLDKLMDHHEIIPNILHYRQLGKLNSTYIEGLL  593
            G ILFE+++LP  + KKTKTGYST+ DVL++L     I+++IL+YRQ+ KL+STY+ GL 
Sbjct  537  GSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQ  596

Query  594  KVVHEDSSKIHTRFNQVLTQTGRLSSTDPNLQNIPIRLEEGRKIRQAFVPSEEGWIMYAA  653
              +  D+ KIHTR+ Q LTQTGRLSS DPNLQNIPIRLE+GR IR+AF PS+E+ ++ ++
Sbjct  597  DYILADG-KIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSS  655

Query  654  DYSQIELRVLAHIANDKGLVDAFQHDMDIHTKTAMDVFGVEKD-EVTSNMRRQAKAVNFG  712
            DYSQIELRVLAHI+ D  L+ AF+++ DIHT TAM VFG++K  +VT+N RR+AKAVNFG
Sbjct  656  DYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFG  715

Query  713  IVYGISDYGLSQNLGITRKAAAEFIEKYLESFPGVQEYMDDIVKDAKQKGYVATLLNRRR  772
            IVYGISD+GLS+NLGITRK +  +I+ Y+E +PG++ YM+++V++AK+KGYV TL++RRR
Sbjct  716  IVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRR  775

Query  773  YIPEITSRNFNLRSFAERTAMNTPIQGTaadiikkamiimadRLEEEGLQARLLLQVHDE  832
             +P+I SRNFN+RSFAERTA+N+PIQG+AADI+K AMI +   L+  G++A++LLQVHDE
Sbjct  776  ELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDE  835

Query  833  LIFEAPKEEIEKLEKLVPEVMEHAIELAVPLKVDYSYGPTWYDAK  877
            +++E P++E+  + KLV + ME A++LAVPL VD S G +WY+AK
Sbjct  836  IVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

217) polA in NC_014335


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  731 bits (2767),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 446/885 (51%), Positives = 663/885 (75%), Gaps = 19/885 (2%)

Query  3    KKVVLVDGNNIAYRAFFAL----PLLNNDKGIHTNAIYGFTMMLMRILEEEKPTHMLVAF  58
            +K++L+DG+++A+RAFFAL      ++N+ G+HTNAIYGF +ML +++   +PTH+LVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  59   DAGKTTFRHKTYSEYKGGRQKTPPELSEQFPFIREMLDAFNVPRYELENYEADDIMGTLA  118
            DAGKTTFR   Y++YK+GR KTP E+ EQF++IREML A+ ++ YELE+YEADDI+GTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  119  K--EASEQGASVKVISGDKDLLQLVSDNTLVCIPRKGITEVDEYTKEALFEKYSLSPKQI  176
            K  E +E    V ++SGDKDL+QL  +NT+V I++KG++E +E+T   L EK +L+P+Q+
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  177  IDMKGLMGDQSDNIPGVPGVGEKTAIKLLTQFGTVEEVYENIDQVSGKKLKEKLEANKDQ  236
            ID+K+LMGD+SDNIPGV  +GEKT++KLL +FG++E +YE+ID     K+KE+L  ++DQ
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRDQ  244

Query  237  ALMSKDLATIITDAPITVHVDDMEYKGYEPSDVIPMFENLGFTSLLNKLGVTPEETAPAE  296
            A++SK LATI T +PIT+ +DD+ Y+G + + +   +++++F  L + L+    + +   
Sbjct  245  AFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLA---SQMPQEP  301

Query  297  LDDITFDIVEEVTEEMLQQDSALIVEVQEDNYHKADIQGFGIQNENGCYFIQTDIAL-KS  355
            +  I+++ V +V+ +++  +  +  E   DNYH+  I GF+  + +  Y   TD++L  +
Sbjct  302  VAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIY-ASTDLSLLAT  360

Query  356  DAFKEWLADGEMRKYTFDAKRAIVALKWNGIDMQGIDFDLLIAAYLLDPADTDKDFRTVA  415
            D+FK+ + +  +  Y F  KR+ V L   GI++ +  +D  +A YLL   + D+++ T+A
Sbjct  361  DSFKQ-VFQKPIATYDF--KRSKVLLSHLGIELVAPSYDARLANYLLSTVE-DNELSTIA  416

Query  416  KMKETHAVKSDEEVYGKGAKRAVPELEIVAEHVARKVHVLYDVKQTFVEELEKNEQYELF  475
            ++    ++  D+ VYGKGAKRAVP+ +++ EH+ARKV VL D K   ++ L  +EQ +L+
Sbjct  417  RIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLY  476

Query  476  TELELPLARVLADMEVKGVKVDTERLRNMGEELAGRLKEMEQEIYKLAGTEFNINSPKQL  535
             ++ELPLA VLA ME+ G+KV+   L++M+E+    +  + QEIY +AG EFNINSPKQL
Sbjct  477  QNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQL  536

Query  536  GVILFENLNLP--VIKKTKTGYSTSADVLDKLMDHHEIIPNILHYRQLGKLNSTYIEGLL  593
            G ILFE+++LP  + KKTKTGYST+ DVL++L     I+++IL+YRQ+ KL+STY+ GL 
Sbjct  537  GSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQ  596

Query  594  KVVHEDSSKIHTRFNQVLTQTGRLSSTDPNLQNIPIRLEEGRKIRQAFVPSEEGWIMYAA  653
              +  D+ KIHTR+ Q LTQTGRLSS DPNLQNIPIRLE+GR IR+AF PS+E+ ++ ++
Sbjct  597  DYILADG-KIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSS  655

Query  654  DYSQIELRVLAHIANDKGLVEAFQHDMDIHTKTAMDVFGVEKD-EVTSNMRRQAKAVNFG  712
            DYSQIELRVLAHI+ D  L+ AF+++ DIHT TAM VFG++K  +VT+N RR+AKAVNFG
Sbjct  656  DYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFG  715

Query  713  IVYGISDYGLSQNLGITRKAAAEFIEKYLESFPGVQEYMDDIVKDAKQKGYVATLLNRRR  772
            IVYGISD+GLS+NLGITRK +  +I+ Y+E +PG++ YM+++V++AK+KGYV TL++RRR
Sbjct  716  IVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRR  775

Query  773  YIPEITSRNFNLRSFAERTAMNTPIQGTaadiikkamiimadRLEEEGLQARLLLQVHDE  832
             +P+I SRNFN+RSFAERTA+N+PIQG+AADI+K AMI +   L+  G++A++LLQVHDE
Sbjct  776  ELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDE  835

Query  833  LIFEAPKEEIEKLEKLVPEVMEHAIELAVPLKVDYSYGPTWYDAK  877
            +++E P++E+  + KLV + ME A++LAVPL VD S G +WY+AK
Sbjct  836  IVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

218) BCN_4487 in NC_016771


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  731 bits (2767),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 446/885 (51%), Positives = 663/885 (75%), Gaps = 19/885 (2%)

Query  3    KKVVLVDGNNIAYRAFFAL----PLLNNDKGIHTNAIYGFTMMLMRILEEEKPTHMLVAF  58
            +K++L+DG+++A+RAFFAL      ++N+ G+HTNAIYGF +ML +++   +PTH+LVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  59   DAGKTTFRHKTYSEYKGGRQKTPPELSEQFPFIREMLDAFNVPRYELENYEADDIMGTLA  118
            DAGKTTFR   Y++YK+GR KTP E+ EQF++IREML A+ ++ YELE+YEADDI+GTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  119  K--EASEQGASVKVISGDKDLLQLVSDNTLVCIPRKGITEVDEYTKEALFEKYSLSPKQI  176
            K  E +E    V ++SGDKDL+QL  +NT+V I++KG++E +E+T   L EK +L+P+Q+
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  177  IDMKGLMGDQSDNIPGVPGVGEKTAIKLLTQFGTVEEVYENIDQVSGKKLKEKLEANKDQ  236
            ID+K+LMGD+SDNIPGV  +GEKT++KLL +FG++E +YE+ID     K+KE+L  ++DQ
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRDQ  244

Query  237  ALMSKDLATIITDAPITVHVDDMEYKGYEPSDVIPMFENLGFTSLLNKLGVTPEETAPAE  296
            A++SK LATI T +PIT+ +DD+ Y+G + + +   +++++F  L + L+    + +   
Sbjct  245  AFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLA---SQMPQEP  301

Query  297  LDDITFDIVEEVTEEMLQQDSALIVEVQEDNYHKADIQGFGIQNENGCYFIQTDIAL-KS  355
            +  I+++ V +V+ +++  +  +  E   DNYH+  I GF+  + +  Y   TD++L  +
Sbjct  302  VAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIY-ASTDLSLLAT  360

Query  356  DAFKEWLADGEMRKYTFDAKRAIVALKWNGIDMQGIDFDLLIAAYLLDPADTDKDFRTVA  415
            D+FK+ + +  +  Y F  KR+ V L   GI++ +  +D  +A YLL   + D+++ T+A
Sbjct  361  DSFKQ-VFQKPIATYDF--KRSKVLLSHLGIELVAPSYDARLANYLLSTVE-DNELSTIA  416

Query  416  KMKETHAVKSDEEVYGKGAKRAVPELEIVAEHVARKVHVLYDVKQTFVEELEKNEQYELF  475
            ++    ++  D+ VYGKGAKRAVP+ +++ EH+ARKV VL D K   ++ L  +EQ +L+
Sbjct  417  RIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLY  476

Query  476  TELELPLARVLADMEVKGVKVDTERLRNMGEELAGRLKEMEQEIYKLAGTEFNINSPKQL  535
             ++ELPLA VLA ME+ G+KV+   L++M+E+    +  + QEIY +AG EFNINSPKQL
Sbjct  477  QNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQL  536

Query  536  GVILFENLNLP--VIKKTKTGYSTSADVLDKLMDHHEIIPNILHYRQLGKLNSTYIEGLL  593
            G ILFE+++LP  + KKTKTGYST+ DVL++L     I+++IL+YRQ+ KL+STY+ GL 
Sbjct  537  GSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQ  596

Query  594  KVVHEDSSKIHTRFNQVLTQTGRLSSTDPNLQNIPIRLEEGRKIRQAFVPSEEGWIMYAA  653
              +  D+ KIHTR+ Q LTQTGRLSS DPNLQNIPIRLE+GR IR+AF PS+E+ ++ ++
Sbjct  597  DYILADG-KIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSS  655

Query  654  DYSQIELRVLAHIANDKGLVDAFQHDMDIHTKTAMDVFGVEKD-EVTSNMRRQAKAVNFG  712
            DYSQIELRVLAHI+ D  L+ AF+++ DIHT TAM VFG++K  +VT+N RR+AKAVNFG
Sbjct  656  DYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFG  715

Query  713  IVYGISDYGLSQNLGITRKAAAEFIEKYLESFPGVQEYMDDIVKDAKQKGYVATLLNRRR  772
            IVYGISD+GLS+NLGITRK +  +I+ Y+E +PG++ YM+++V++AK+KGYV TL++RRR
Sbjct  716  IVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRR  775

Query  773  YIPEITSRNFNLRSFAERTAMNTPIQGTaadiikkamiimadRLEEEGLQARLLLQVHDE  832
             +P+I SRNFN+RSFAERTA+N+PIQG+AADI+K AMI +   L+  G++A++LLQVHDE
Sbjct  776  ELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDE  835

Query  833  LIFEAPKEEIEKLEKLVPEVMEHAIELAVPLKVDYSYGPTWYDAK  877
            +++E P++E+  + KLV + ME A++LAVPL VD S G +WY+AK
Sbjct  836  IVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

219) polA in NC_015978


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  730 bits (2763),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 446/899 (50%), Positives = 655/899 (73%), Gaps = 27/899 (3%)

Query  4    KKLLLIDGNSLTYKAFFALYTSMDRFTSPDGLHTSAVYGFNRMLNDILADIKPTTVLAAF  63
            +KLLLIDG+S++++AFFALY  +DRF +  GLHT+A+YGF+ ML++++  ++PT VL AF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  64   DAGKKTFRTKMYSDYKAGRAKMPDELREQFPYVMDLLKARGIKTYELKDYEADDIIGTTA  123
            DAGK TFRT MY+DYKAGRAK PDE+REQF+Y+ ++L A GI  YEL +YEADDIIGT  
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  124  KIAEKEG--YHVDIITGDRDLTQLCSEkttvkvskkgvsDLEDYTPTYVKKNMGINPEQI  181
            K+AE+    ++V I++GD+DL QL  E+T V +SKKGV+++E++TP+Y+  +MG+ P+Q+
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  182  IDIKGLQGDTSDNYPGVEKVGPKTAIKLIKQYGTVQGLYDHIDEITAKKLKEHLVNDEKQ  241
            ID+K+L GD SDN PGV K+G KT++KL+ ++G+++G+Y+HID + + K+KE+L+ND  Q
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRDQ  244

Query  242  AFLSKKLATIDTNAPIDIKLADLIYKGPQEPELSDFYKKMGFKSFLNSSNNADNQLGTSK  301
            AFLSK LATI+T +PI I L D++Y+GP+ + LS+FY  M+F   ++  +   +Q+    
Sbjct  245  AFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDF---VQLKKGLASQMPQEP  301

Query  302  IELPEVEFTELSKENLDEVNSLGNEITFNLETINPNYHTAEQLGFVIGNGKKWFVSRDMS  361
            + +  + + E+++ +    + ++ E  F +ET+  NYH    +GF  G+G + + S D+S
Sbjct  302  VAV--ISYQEVTNVS---ADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLS  356

Query  362  LLSDKRIKQILENSEINKNIFDTKAQIVGLHRNEIGFQGVDFDMLLVSYLINTLNNEDDI  421
            LL+   +KQ+++++      +D K   V L +  I + +  +D  L +YL++T++ ++++
Sbjct  357  LLATDSFKQVFQKP---IATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVE-DNEL  412

Query  422  GEVANRHGYFGVLSDEEVYGKGKSFQIPDNHELFEHMVRKALAISTLKKQMLEKLKEHQQ  481
            + +A     +++  D+ VYGKG    +PD++ L+EH+ RK   +   K QML+KL  H+Q
Sbjct  413  STIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQ  472

Query  482  ADLYRDLELPLARVLSAMEIQGISVNQDKLEELKSKFTERVSEYKQKIYQEAGEEFNIGS  541
             DLY+++ELPLA VL+ MEI+GI VN+  L+++  +    +    Q IY+ AG+EFNI S
Sbjct  473  LDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINS  532

Query  542  PKQLGIVLFEKMGLP--VIKKTKTGYSTAVDVLEQLAPDHPIIENILNYRQLTKLISTYL  599
            PKQLG +LFEKM LP  + KKTKTGYSTAVDVLE+LAP  PI+ +IL+YRQ+TKL STY+
Sbjct  533  PKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYV  592

Query  600  DGIKADITDDGKVHTRYLQTLTQTGRLSSVDPNLQNIPVRTEEGRKVRETFVPSHKGWKL  659
             G++  I  DGK+HTRY+Q LTQTGRLSSVDPNLQNIP+R E+GR +R +F PSH +  L
Sbjct  593  IGLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVL  652

Query  660  FSSDYSQIELRVLAAISGDKNMREAFESGEDIHAATARRIFELDKDAVITPTLRRQAKAV  719
            +SSDYSQIELRVLA ISGD ++  AF+ G DIH++TA R+F +DK A +T+  RR+AKAV
Sbjct  653  LSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAV  712

Query  720  NFGIVYGISSFGLAHNTGISNGDAKRFIDKYFNEYPGVKQYMEDSVKFAKEHGYVETISH  779
            NFGIVYGIS FGL++N GI+  ++K +ID YF+ YPG+K YME+ V+ AK+ GYVET+  
Sbjct  713  NFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFK  772

Query  780  RRRYIPEIQSKRFQQRQFAERIAMNSPIQGSaadiikaamikmQSVLKEKGLQAKMLLQI  839
            RRR +P+I+S+ F+ R FAER A+NSPIQGSAADI+K AMI+++  L+  G++AKMLLQ+
Sbjct  773  RRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQV  832

Query  840  HDELIFEAPETEIPVLEKLVPQVMDSIMKTDKLLSNSTVDFNVPLKVESHPGSDWYNIK  898
            HDE+++E P+ E+  + KLV + M+           ++VD+ VPL V+   G  WY+ K
Sbjct  833  HDEIVLEVPNDELTAIKKLVKDTME-----------AAVDLAVPLCVDESTGQSWYEAK  880

220) GTNG_2654 in NC_009328


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  728 bits (2754),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 448/887 (51%), Positives = 646/887 (73%), Gaps = 16/887 (1%)

Query  1    MRLKKKLVLIDGNSVAYRAFFAL----PLLHNDKGIHTNAVYGFTMMLNKILAEEQPTHL  56
            M  K+KL+LIDG+SVA+RAFFAL      + N+ G+HTNA+YGF +ML+ ++   +PTH+
Sbjct  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60

Query  57   LVAFDAGKTTFRHETFQEYKGGRQQTPPELSEQFPLLRELLKAYRIPAYELDHYEADDII  116
            LVAFDAGKTTFR E + +YK+GR +TP E+ EQF+ +RE+L A  I+ YEL+HYEADDII
Sbjct  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120

Query  117  GTLAARAEQEG--FEVKIISGDRDLTQLASRHVTVDITKKGITDIEPYTPETVREKYGLT  174
            GTL   AE+    F+V I+SGD+DL QL+  +  V+I+KKG++++E +TP  + EK GLT
Sbjct  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180

Query  175  PEQIVDLKGLMGDKSDNIPGVPGIGEKTAVKLLKQFGTVENVLASIDEVKGEKLKENLRQ  234
            P+Q++DLK+LMGDKSDNIPGV  IGEKT++KLL +FG++E +   ID  K  K+KENL +
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  235  HRDLALLSKQLASICRDAPVELSLDDIVYEGQDREKVIALFKELGFQSFLEKMAAPAAEG  294
            +RD A+LSK LA+I   +P+ ++LDDIVY+G D   +  ++ E++F  +  K + ++   
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQL--KKGLASQMP  298

Query  295  EKPLEEMEFAIVDVITEEMLADKAALVVEVMEENYHDAPIVGIALVNEHGRFFMRPETAL  354
            + P+  + +  V  ++ ++++    +  E + +NYH  +I+G+A  + + +++   + +L
Sbjct  299  QEPVAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGE-QIYASTDLSL  357

Query  355  ADSQFLAWLADETKKKSMFDAKRAVVALKWKGIELRGVAFDLLLAAYLLNPAQDAGDIAA  414
              ++ +  + +  K  + +D KR+ V L   GIEL + ++D  LA YLL+  +D  ++++
Sbjct  358  LATDSFKQVFQ--KPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NELST  414

Query  415  VAKMKQYEAVRSDEAVYGKGVKRSLPDEQTLAEHLVRKAAAIWALEQPFMDDLRNNEQDQ  474
            +A++    ++  D++VYGKG KR++PD + L EHL RK   +       +D L  +EQ +
Sbjct  415  IARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLD  474

Query  475  LLTKLEQPLAAILAEMEFTGVNVDTKRLEQMGSELAEQLRAIEQRIYELAGQEFNINSPK  534
            L  ++E PLA +LA ME+ G++V+   L++M+ +    + A+ Q IY++AGQEFNINSPK
Sbjct  475  LYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPK  534

Query  535  QLGVILFEKLQLP--VLKKTKTGYSTSADVLEKLAPHHEIVENILHYRQLGKLQSTYIEG  592
            QLG ILFEK+QLP  + KKTKTGYST+ DVLE+LAP   IV +IL+YRQ+ KLQSTY+ G
Sbjct  535  QLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIG  594

Query  593  LLKVVRPDTGKVHTMFNQALTQTGRLSSAEPNLQNIPIRLEEGRKIRQAFVPSEPDWLIF  652
            L   + +D GK+HT + Q LTQTGRLSS +PNLQNIPIRLE+GR IR+AF PS+ D +++
Sbjct  595  LQDYILAD-GKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLL  653

Query  653  AADYSQIELRVLAHIADDDNLIEAFQRDLDIHTKTAMDIFHVS-EEEVTANMRRQAKAVN  711
            ++DYSQIELRVLAHI++D++LI AF+ + DIHT TAM +F +    +VTAN RR+AKAVN
Sbjct  654  SSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVN  713

Query  712  FGIVYGISDYGLAQNLNITRKEAAEFIERYFASFPGVKQYMENIVQEAKQKGYVTTLLHR  771
            FGIVYGISD+GL++NL ITRK++  +I+ YF  +PG+K YMEN+V+EAK+KGYV TL+ R
Sbjct  714  FGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKR  773

Query  772  RRYLPDITSRNFNVRSFAERTAMNTPIQGSAADIIKKAMIDLAARLKEEQLQARLLLQVH  831
            RR LPDI SRNFNVRSFAERTA+N+PIQGSAADI+K AMI+L   L+   ++A++LLQVH
Sbjct  774  RRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVH  833

Query  832  DELILEAPKEEIERLCELVPEVMEQAVTLRVPLKVDYHYGPTWYDAK  878
            DE++LE P++E+  +  LV + ME AV L VPL VD   G +WY+AK
Sbjct  834  DEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

221) polA in NC_011772


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  727 bits (2750),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 444/885 (51%), Positives = 660/885 (75%), Gaps = 19/885 (2%)

Query  3    KKVVLVDGNNIAYRAFFAL----PLLNNDKGIHTNAIYGFTMMLMRILEEEKPTHMLVAF  58
            +K++L+DG+++A+RAFFAL      ++N+ G+HTNAIYGF +ML +++   +PTH+LVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  59   DAGKTTFRHKTYSEYKGGRQKTPPELSEQFPFIREMLDAFNVPRYELENYEADDIMGTLA  118
            DAGKTTFR   Y++YK+GR KTP E+ EQF++IREML A+ ++ YELE+YEADDI+GTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  119  K--EASEQGASVKVISGDKDLLQLVSDNTLVCIPRKGITEVDEYTKEALFEKYSLSPKQI  176
            K  E +E    V ++SGDKDL+QL  +NT+V I++KG++E +E+T   L EK +L+P+Q+
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  177  IDMKGLMGDQSDNIPGVPGVGEKTAIKLLTQFGTVEEVYDNLDQVSGKKLKEKLEANKDQ  236
            ID+K+LMGD+SDNIPGV  +GEKT++KLL +FG++E +Y+++D     K+KE+L  ++DQ
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRDQ  244

Query  237  ALMSKDLATIITDAPITVHVDDMEYKGYEASDVVPMFESLGFTSLLNKLGVTPEETAPAE  296
            A++SK LATI T +PIT+ +DD+ Y+G + + +   ++ ++F  L + L+    + +   
Sbjct  245  AFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLA---SQMPQEP  301

Query  297  LDDITFDIVEEVTEEMLQQDSALIVEVQEDNYHKADIQGFGIQNENGCYFIQKDIAL-KS  355
            +  I+++ V +V+ +++  +  +  E   DNYH+  I GF+  + +  Y    D++L  +
Sbjct  302  VAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIY-ASTDLSLLAT  360

Query  356  DAFKDWLADGEMRKHTFDAKRAIVALKWNGIDIQGVDFDLLIAAYLLDPADTDKDFRTVA  415
            D+FK+ +   +    T+D KR+ V L   GI++ +  +D  +A YLL   + D+++ T+A
Sbjct  361  DSFKQVF---QKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVE-DNELSTIA  416

Query  416  KMKETHAVKSDEEVYGKGAKRAVPELKVVAEHVARKVHVLYDVKQTFVEELEKNEQYELF  475
            ++    ++  D+ VYGKGAKRAVP+  V+ EH+ARKV VL D K   ++ L  +EQ +L+
Sbjct  417  RIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLY  476

Query  476  TELELPLARVLADMEVKGVKVDTERLRNMGEELAGRLKEMEQEIYKLAGTEFNINSPKQL  535
             ++ELPLA VLA ME+ G+KV+   L++M+E+    +  + QEIY +AG EFNINSPKQL
Sbjct  477  QNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQL  536

Query  536  GVILFENLNLP--VIKKTKTGYSTSADVLDKLMDHHEIIPNILHYRQLGKLNSTYIEGLL  593
            G ILFE+++LP  + KKTKTGYST+ DVL++L     I+++IL+YRQ+ KL+STY+ GL 
Sbjct  537  GSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQ  596

Query  594  KVVHEDSSKIHTRFNQVLTQTGRLSSTDPNLQNIPIRLEEGRKIRQAFVPSEEGWIMYAA  653
              +  D+ KIHTR+ Q LTQTGRLSS DPNLQNIPIRLE+GR IR+AF PS+E+ ++ ++
Sbjct  597  DYILADG-KIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSS  655

Query  654  DYSQIELRVLAHIANDKGLVEAFQHDMDIHTKTAMDVFGVEKD-EVTSNMRRQAKAVNFG  712
            DYSQIELRVLAHI+ D  L+ AF+++ DIHT TAM VFG++K  +VT+N RR+AKAVNFG
Sbjct  656  DYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFG  715

Query  713  IVYGISDYGLSQNLGITRKAAAEFIEKYLESFPGVQEYMEDIVKDAKQKGYVATLLNRRR  772
            IVYGISD+GLS+NLGITRK +  +I+ Y+E +PG++ YME++V++AK+KGYV TL++RRR
Sbjct  716  IVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRR  775

Query  773  YIPEITSRNFNLRSFAERTAMNTPIQGTaadiikkamiimadRLEEEGLQARLLLQVHDE  832
             +P+I SRNFN+RSFAERTA+N+PIQG+AADI+K AMI +   L+  G++A++LLQVHDE
Sbjct  776  ELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDE  835

Query  833  LIFEAPKEEIEKLEQLVPEVMEHAIELAVPLKVDYSYGPTWYDAK  877
            +++E P++E+  + +LV + ME A++LAVPL VD S G +WY+AK
Sbjct  836  IVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

222) BTF1_21475 in NC_018508


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  727 bits (2750),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 444/885 (51%), Positives = 660/885 (75%), Gaps = 19/885 (2%)

Query  3    KKVVLVDGNNIAYRAFFAL----PLLNNDKGIHTNAIYGFTMMLMRILEEEKPTHMLVAF  58
            +K++L+DG+++A+RAFFAL      ++N+ G+HTNAIYGF +ML +++   +PTH+LVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  59   DAGKTTFRHKTYSEYKGGRQKTPPELSEQFPFIREMLDAFNVPRYELENYEADDIMGTLA  118
            DAGKTTFR   Y++YK+GR KTP E+ EQF++IREML A+ ++ YELE+YEADDI+GTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  119  K--EASEQGASVKVISGDKDLLQLVSDNTLVCIPRKGITEVDEYTKEALFEKYSLSPKQI  176
            K  E +E    V ++SGDKDL+QL  +NT+V I++KG++E +E+T   L EK +L+P+Q+
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  177  IDMKGLMGDQSDNIPGVPGVGEKTAIKLLTQFGTVEEVYDNLDQVSGKKLKEKLEANKDQ  236
            ID+K+LMGD+SDNIPGV  +GEKT++KLL +FG++E +Y+++D     K+KE+L  ++DQ
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRDQ  244

Query  237  ALMSKDLATIITDAPITVHVDDMEYKGYEASDVVPMFESLGFTSLLNKLGVTPEETAPAE  296
            A++SK LATI T +PIT+ +DD+ Y+G + + +   ++ ++F  L + L+    + +   
Sbjct  245  AFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLA---SQMPQEP  301

Query  297  LDDITFDIVEEVTEEMLQQDSALIVEVQEDNYHKADIQGFGIQNENGCYFIQKDIAL-KS  355
            +  I+++ V +V+ +++  +  +  E   DNYH+  I GF+  + +  Y    D++L  +
Sbjct  302  VAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIY-ASTDLSLLAT  360

Query  356  DAFKDWLADGEMRKHTFDAKRAIVALKWNGIDIQGVDFDLLIAAYLLDPADTDKDFRTVA  415
            D+FK+ +   +    T+D KR+ V L   GI++ +  +D  +A YLL   + D+++ T+A
Sbjct  361  DSFKQVF---QKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVE-DNELSTIA  416

Query  416  KMKETHAVKSDEEVYGKGAKRAVPELKVVAEHVARKVHVLYDVKQTFVEELEKNEQYELF  475
            ++    ++  D+ VYGKGAKRAVP+  V+ EH+ARKV VL D K   ++ L  +EQ +L+
Sbjct  417  RIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLY  476

Query  476  TELELPLARVLADMEVKGVKVDTERLRNMGEELAGRLKEMEQEIYKLAGTEFNINSPKQL  535
             ++ELPLA VLA ME+ G+KV+   L++M+E+    +  + QEIY +AG EFNINSPKQL
Sbjct  477  QNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQL  536

Query  536  GVILFENLNLP--VIKKTKTGYSTSADVLDKLMDHHEIIPNILHYRQLGKLNSTYIEGLL  593
            G ILFE+++LP  + KKTKTGYST+ DVL++L     I+++IL+YRQ+ KL+STY+ GL 
Sbjct  537  GSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQ  596

Query  594  KVVHEDSSKIHTRFNQVLTQTGRLSSTDPNLQNIPIRLEEGRKIRQAFVPSEEGWIMYAA  653
              +  D+ KIHTR+ Q LTQTGRLSS DPNLQNIPIRLE+GR IR+AF PS+E+ ++ ++
Sbjct  597  DYILADG-KIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSS  655

Query  654  DYSQIELRVLAHIANDKGLVEAFQHDMDIHTKTAMDVFGVEKD-EVTSNMRRQAKAVNFG  712
            DYSQIELRVLAHI+ D  L+ AF+++ DIHT TAM VFG++K  +VT+N RR+AKAVNFG
Sbjct  656  DYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFG  715

Query  713  IVYGISDYGLSQNLGITRKAAAEFIEKYLESFPGVQEYMEDIVKDAKQKGYVATLLNRRR  772
            IVYGISD+GLS+NLGITRK +  +I+ Y+E +PG++ YME++V++AK+KGYV TL++RRR
Sbjct  716  IVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRR  775

Query  773  YIPEITSRNFNLRSFAERTAMNTPIQGTaadiikkamiimadRLEEEGLQARLLLQVHDE  832
             +P+I SRNFN+RSFAERTA+N+PIQG+AADI+K AMI +   L+  G++A++LLQVHDE
Sbjct  776  ELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDE  835

Query  833  LIFEAPKEEIEKLEQLVPEVMEHAIELAVPLKVDYSYGPTWYDAK  877
            +++E P++E+  + +LV + ME A++LAVPL VD S G +WY+AK
Sbjct  836  IVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

223) BTG_25930 in NC_018500


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  726 bits (2746),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 444/885 (51%), Positives = 659/885 (75%), Gaps = 19/885 (2%)

Query  3    KKVVLVDGNNIAYRAFFAL----PLLNNDKGIHTNAIYGFTMMLMRILEEEKPTHMLVAF  58
            +K++L+DG+++A+RAFFAL      ++N+ G+HTNAIYGF +ML +++   +PTH+LVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  59   DAGKTTFRHKTYSEYKGGRQKTPPELSEQFPFIREMLDAFNVPRYELENYEADDIMGTLA  118
            DAGKTTFR   Y++YK+GR KTP E+ EQF++IREML A+ ++ YELE+YEADDI+GTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  119  K--EASEQGASVKVISGDKDLLQLVSDNTLVCIPRKGITEVDEYTKEALFEKYSLSPKQI  176
            K  E +E    V ++SGDKDL+QL  +NT+V I++KG++E +E+T   L EK +L+P+Q+
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  177  IDMKGLMGDQSDNIPGVPGVGEKTAIKLLTQFGTVEEVYDNLDQVSGKKLKEKLEANKDQ  236
            ID+K+LMGD+SDNIPGV  +GEKT++KLL +FG++E +Y+++D     K+KE+L  ++DQ
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRDQ  244

Query  237  ALMSKDLATIITDAPITVHVDDMEYKGYEASDVVPMFESLGFTSLLNKLGVTPEETAPAE  296
            A++SK LATI T +PIT+ +DD+ Y+G + + +   ++ ++F  L + L+    + +   
Sbjct  245  AFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLA---SQMPQEP  301

Query  297  LDDITFDIVEEVTEEMLQQDSALIVEVQEDNYHKADIQGFGIQNENGCYFIQKDIAL-KS  355
            +  I+++ V +V+ +++  +  +  E   DNYH+  I GF+  + +  Y    D++L  +
Sbjct  302  VAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIY-ASTDLSLLAT  360

Query  356  DAFKDWLADGEMRKHTFDAKRAIVALKWNGIDIQGVDFDLLIAAYLLDPADTDKDFRTVA  415
            D+FK+ +   +    T+D KR+ V L   GI++ +  +D  +A YLL   + D+++ T+A
Sbjct  361  DSFKQVF---QKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVE-DNELSTIA  416

Query  416  KMKETHAVKSDEEVYGKGAKRAVPELKVVAEHVARKVHVLYDVKQTFVEELEKNEQYELF  475
            ++    ++  D+ VYGKGAKRAVP+  V+ EH+ARKV VL D K   ++ L  +EQ +L+
Sbjct  417  RIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLY  476

Query  476  TELELPLARVLADMEVKGVKVDTERLRNMGEELAGRLKEMEQEIYKLAGTEFNINSPKQL  535
             ++ELPLA VLA ME+ G+KV+   L++M+E+    +  + QEIY +AG EFNINSPKQL
Sbjct  477  QNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQL  536

Query  536  GVILFENLNLP--VIKKTKTGYSTSADVLDKLMDHHEIIPNILHYRQLGKLNSTYIEGLL  593
            G ILFE+++LP  + KKTKTGYST+ DVL++L     I+++IL+YRQ+ KL+STY+ GL 
Sbjct  537  GSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQ  596

Query  594  KVVHEDSSKIHTRFNQVLTQTGRLSSTDPNLQNIPIRLEEGRKIRQAFVPSEEGWIMYAA  653
              +  D+ KIHTR+ Q LTQTGRLSS DPNLQNIPIRLE+GR IR+AF PS+E+ ++ ++
Sbjct  597  DYILADG-KIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSS  655

Query  654  DYSQIELRVLAHIANDKGLVEAFQHDMDIHTKTAMDVFGVEKD-EVTSNMRRQAKAVNFG  712
            DYSQIELRVLAHI+ D  L+ AF+++ DIHT TAM VFG++K  +VT+N RR+AKAVNFG
Sbjct  656  DYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFG  715

Query  713  IVYGISDYGLSQNLGITRKAAAEFIEKYLESFPGVQEYMEDIVKDAKRKGYVATLLNRRR  772
            IVYGISD+GLS+NLGITRK +  +I+ Y+E +PG++ YME++V++AK KGYV TL++RRR
Sbjct  716  IVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRR  775

Query  773  YIPEITSRNFNLRSFAERTAMNTPIQGTaadiikkamiimadRLEEEGLQARLLLQVHDE  832
             +P+I SRNFN+RSFAERTA+N+PIQG+AADI+K AMI +   L+  G++A++LLQVHDE
Sbjct  776  ELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDE  835

Query  833  LIFEAPKEEIEKLEQLVPEVMEHAIELAVPLKVDYSYGPTWYDAK  877
            +++E P++E+  + +LV + ME A++LAVPL VD S G +WY+AK
Sbjct  836  IVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

224) polA in NC_011725


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  720 bits (2722),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 447/885 (51%), Positives = 665/885 (76%), Gaps = 19/885 (2%)

Query  3    KKVVLVDGNNIAYRAFFAL----PLLNNDKGIHTNAIYGFTMMLMRILEEEKPTHMLVAF  58
            +K++L+DG+++A+RAFFAL      ++N+ G+HTNAIYGF +ML +++   +PTH+LVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  59   DAGKTTFRHKTYSEYKGGRQKTPPELSEQFPFIREMLDAFNVPRYELENYEADDIMGTLA  118
            DAGKTTFR   Y++YK+GR KTP E+ EQF++IREML A+ ++ YELE+YEADDI+GTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  119  K--EASEQGASVKVISGDKDLLQLVSDNTLVCIPRKGITEVDEYTKEALFEKYSLSPKQI  176
            K  E +E    V ++SGDKDL+QL  +NT+V I++KG++E +E+T   L EK +L+P+Q+
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  177  IDMKGLMGDQSDNIPGVPGVGEKTAIKLLTQFGTVEAVYENIDQVSGkklkekleenkeQ  236
            ID+K+LMGD+SDNIPGV  +GEKT++KLL +FG++E++YE+ID     K+KE+L ++++Q
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRDQ  244

Query  237  ALMSKDLATIITDAPITVHVDDMVYKGYEASDVIPMFESLGFTSLLNKLGVTPEETAPAE  296
            A++SK LATI T +PIT+ +DD+VY+G + + +   ++ ++F  L + L+    + +   
Sbjct  245  AFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLA---SQMPQEP  301

Query  297  LDDITFDIVEEVTEEMLQQDSALIVEVQEDNYHKADIQGFGIQNENGCYFIQTDIAL-KS  355
            +  I+++ V +V+ +++  +  +  E   DNYH+  I GF+  + +  Y   TD++L  +
Sbjct  302  VAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIY-ASTDLSLLAT  360

Query  356  DAFKEWLADGEMRKHTFDAKRAIVALKWNGIDMQGIDFDLLIAAYLLDPADTDKDFRTVA  415
            D+FK+ +   +    T+D KR+ V L   GI++ +  +D  +A YLL   + D+++ T+A
Sbjct  361  DSFKQVF---QKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVE-DNELSTIA  416

Query  416  KMKETHAVKSDEEVYGKGAKRAVPELEVVAEHVARKVHVLYDVKQTFVEELKKNEQYELF  475
            ++    ++  D+ VYGKGAKRAVP+ +V+ EH+ARKV VL D K   ++ L  +EQ +L+
Sbjct  417  RIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLY  476

Query  476  TELELPLARVLADMEVKGVKVDTERLRNMGEELAGRLKEMEQEIYKLAGTEFNINSPKQL  535
             ++ELPLA VLA ME+ G+KV+   L++M+E+    +  + QEIY +AG EFNINSPKQL
Sbjct  477  QNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQL  536

Query  536  GVILFENLNLP--VIKKTKTGYSTSADVLDKLMNHHEIIPNILHYRQLGKLNSTYIEGLL  593
            G ILFE+++LP  + KKTKTGYST+ DVL++L     I+++IL+YRQ+ KL+STY+ GL 
Sbjct  537  GSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQ  596

Query  594  KVVHEDSSKIHTRFNQVLTQTGRLSSTDPNLQNIPIRLEEGRKIRQAFVPSEEGWIMYAA  653
              +  D+ KIHTR+ Q LTQTGRLSS DPNLQNIPIRLE+GR IR+AF PS+E+ ++ ++
Sbjct  597  DYILADG-KIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSS  655

Query  654  DYSQIELRVLAHIANDKGLVEAFQHDMDIHTKTAMDVFGVEKD-EVTSNMRRQAKAVNFG  712
            DYSQIELRVLAHI+ D  L+ AF+++ DIHT TAM VFG++K  +VT+N RR+AKAVNFG
Sbjct  656  DYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFG  715

Query  713  IVYGISDYGLSQNLGITRKAAAEFIEKYLESFPGVQEYMEDIVKDAKQKGYVATLLNRRR  772
            IVYGISD+GLS+NLGITRK +  +I+ Y+E +PG++ YME++V++AK+KGYV TL++RRR
Sbjct  716  IVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRR  775

Query  773  YIPEITSRNFNLRSFAERTAMNTPIQGTaadiikkamiimadRLEEEGLQARLLLQVHDE  832
             +P+I SRNFN+RSFAERTA+N+PIQG+AADI+K AMI +   L+  G++A++LLQVHDE
Sbjct  776  ELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDE  835

Query  833  LIFEAPKEEIEKLEQLVPEVMEHAIELAVPLKVDYSYGPTWYDAK  877
            +++E P++E+  + +LV + ME A++LAVPL VD S G +WY+AK
Sbjct  836  IVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

225) HD73_4882 in NC_020238


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  717 bits (2711),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 447/885 (51%), Positives = 662/885 (75%), Gaps = 19/885 (2%)

Query  3    KKVVLVDGNNIAYRAFFAL----PLLNNDKGIHTNAIYGFTMMLMRILEEEKPTHMLVAF  58
            +K++L+DG+++A+RAFFAL      ++N+ G+HTNAIYGF +ML +++   +PTH+LVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  59   DAGKTTFRHKTYSEYKGGRQKTPPELSEQFPFIREMLDAFNVPRYELENYEADDIMGTLA  118
            DAGKTTFR   Y++YK+GR KTP E+ EQF++IREML A+ ++ YELE+YEADDI+GTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  119  K--EASEQGASVKVISGDKDLLQLVSDNTLVCIPRKGITEVDEYTKEALFEKYSLSPKQI  176
            K  E +E    V ++SGDKDL+QL  +NT+V I++KG++E +E+T   L EK +L+P+Q+
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  177  IDMKGLMGDQSDNIPGVPGVGEKTAIKLLTQFGTVEAVYENIDQVSGkklkekleenkeQ  236
            ID+K+LMGD+SDNIPGV  +GEKT++KLL +FG++E++YE+ID     K+KE+L ++++Q
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRDQ  244

Query  237  ALMSKDLATIITDAPITVRVDDMAYKGYEASDVIPMFESLGFTSLLNKLGVTPEETAPAE  296
            A++SK LATI T +PIT+ +DD+ Y+G + + +   ++ ++F  L + L+    + +   
Sbjct  245  AFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLA---SQMPQEP  301

Query  297  LDDITFDIVEEVTEEMLQQDSALIVEVQEDNYHKADIQGFGIQNENGCYFIQTDIAL-KS  355
            +  I+++ V +V+ +++  +  +  E   DNYH+  I GF+  + +  Y   TD++L  +
Sbjct  302  VAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIY-ASTDLSLLAT  360

Query  356  DAFKEWLADGEMRKHTFDAKRAIVALKWNGIDMQGIDFDLLIAAYLLDPADTDKDFRTVA  415
            D+FK+ +   +    T+D KR+ V L   GI++ +  +D  +A YLL   + D+++ T+A
Sbjct  361  DSFKQVF---QKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVE-DNELSTIA  416

Query  416  KMKETHAVKSDEEVYGKGAKRAVPKLEVVAEHVARKVHVLYDVKQTFVEELKKNEQYELF  475
            ++    ++  D+ VYGKGAKRAVP  +V+ EH+ARKV VL D K   ++ L  +EQ +L+
Sbjct  417  RIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLY  476

Query  476  TELELPLARVLADMEVKGVKVDTERLRNMGEELAGRLKEMEQEIYKLAGTEFNINSPKQL  535
             ++ELPLA VLA ME+ G+KV+   L++M+E+    +  + QEIY +AG EFNINSPKQL
Sbjct  477  QNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQL  536

Query  536  GVILFENLNLP--VIKKTKTGYSTSADVLDKLMNHHEIIPNILHYRQLGKLNSTYIEGLL  593
            G ILFE+++LP  + KKTKTGYST+ DVL++L     I+++IL+YRQ+ KL+STY+ GL 
Sbjct  537  GSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQ  596

Query  594  KVVHEDSSKIHTRFNQVLTQTGRLSSTDPNLQNIPIRLEEGRKIRQAFVPSEEGWIMYAA  653
              +  D+ KIHTR+ Q LTQTGRLSS DPNLQNIPIRLE+GR IR+AF PS+E+ ++ ++
Sbjct  597  DYILADG-KIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSS  655

Query  654  DYSQIELRVLAHIANDKGLVEAFQHDMDIHTKTAMDVFGVKKD-EVTSNMRRQAKAVNFG  712
            DYSQIELRVLAHI+ D  L+ AF+++ DIHT TAM VFG+ K  +VT+N RR+AKAVNFG
Sbjct  656  DYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFG  715

Query  713  IVYGISDYGLSQNLGITRKAAAEFIEKYLESFPGVQEYMEDIVKDAKQKGYVATLLNRRR  772
            IVYGISD+GLS+NLGITRK +  +I+ Y+E +PG++ YME++V++AK+KGYV TL++RRR
Sbjct  716  IVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRR  775

Query  773  YIPEITSRNFNLRSFAERTAMNTPIQGTaadiikkamiimadRLEEEGLQARLLLQVHDE  832
             +P+I SRNFN+RSFAERTA+N+PIQG+AADI+K AMI +   L+  G++A++LLQVHDE
Sbjct  776  ELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDE  835

Query  833  LIFEAPKEEIEKLEKLVPEVMEHAIELAVPLKVDYSYGPTWYDAK  877
            +++E P++E+  + KLV + ME A++LAVPL VD S G +WY+AK
Sbjct  836  IVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

226) polA in NC_014103


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  717 bits (2714),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 439/882 (50%), Positives = 654/882 (75%), Gaps = 15/882 (1%)

Query  3    QKLVLIDGNSIAYRAFFAL----PLLNNDKGIHTNAIYGFTTMLTRILEEEKPTHLLVAF  58
            +KL+LIDG+S+A+RAFFAL      ++N+ G+HTNAIYGF  ML +++   +PTH+LVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  59   DAGKTTFRHKTFTEYKGGRQKTPPELSEQFPFIRELLDAYGIKRYELPDYEADDIIGTLS  118
            DAGKTTFR   +++YK+GR KTP E+ EQF++IRE+L A GI  YEL +YEADDIIGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  119  KQAEQKGMA--VKVISGDKDLLQLVSEHVTVDITRKGITDVDSYTPAAIDEKYGITAAQI  176
            K AE+  ++  V ++SGDKDL+QL  E+  V+I++KG+++ + +TPA + EK G+T+ Q+
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  177  IDMKGLMGDSSDNIPGVPGVGEKTALKLLKEFETVENVLKSIDQVSGKKLKEKLEDNRES  236
            ID+K+LMGD SDNIPGV  +GEKT+LKLL EF ++E +   ID     K+KE+L ++R+ 
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRDQ  244

Query  237  AIMSKKLATIYCEAPLEVSVEDAKYDGFESSKVISLFKELGFNSLLAKfgesaeeeadfe  296
            A++SK LATI   +P+ ++++D  Y+G + + +  ++ E++F  L  K   S   +    
Sbjct  245  AFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQL-KKGLASQMPQEPVA  303

Query  297  eitfeiaQEVHDDMLTSEAALIVEGYEENYHHNQLLGFGISNNNGHYFIDKDTALSSSKF  356
             I+++   +V  D++++E  +  E   +NYH++ ++GF+ ++ +  Y     + L++  F
Sbjct  304  VISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLATDSF  363

Query  357  KAWLEDGRVKKTVFNGKRTIVSLKWAGHEIKGIEHDVMIASYILNPAEANDDLATIAKLK  416
            K  ++      + ++ KR+ V L   G E+ +   D  +A+Y+L+  E +++L+TIA++ 
Sbjct  364  KQVFQKP---IATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVE-DNELSTIARIF  419

Query  417  GYHQVQSDEAVYGKGAKRSIAEADQLAEHVIRKAAAVAYlkevlekelveNEQFELFEKL  476
                ++ D++VYGKGAKR++++ D L EH+ RK   +   K  +   L  +EQ++L++++
Sbjct  420  TDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNI  479

Query  477  EMPLAIVLADMEYQGVKIDRARLDEMGEDLREQLEKIEAKIYEYAGQEFNINSPKQLGVV  536
            E+PLA VLA ME +G+K++RA L++M+E+ +  +E +   IY+ AGQEFNINSPKQLG +
Sbjct  480  ELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSI  539

Query  537  LFEKMQLP--VIKKTKTGYSTSADVLEQLASTHDIIPEILQYRQLGKLQSTYIEGLKKVI  594
            LFEKMQLP  + KKTKTGYST+ DVLE+LA+   I++ IL+YRQ+ KLQSTY+ GL+  I
Sbjct  540  LFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYI  599

Query  595  HESDGKVHTRFNQTLTQTGRLSSVDPNLQNIPIRLEEGKKIRGAFVPSQPGWLIFAADYS  654
              +DGK+HTR+ Q LTQTGRLSSVDPNLQNIPIRLE+G+ IR AF PS+ + +++++DYS
Sbjct  600  L-ADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYS  658

Query  655  QIELRVLAHIADDEKLIDAFKHDLDIHTKTAMDVFHVERE-EVTANMRRQAKAVNFGIVY  713
            QIELRVLAHI++DE LI AF+++ DIHT TAM VF +++  +VTAN RR+AKAVNFGIVY
Sbjct  659  QIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVY  718

Query  714  GISDYGLSQSLGITRKAAATFIERYLKSFPGVQEYMDTIVRDAKEKGYVTTLLHRRRYLP  773
            GISD+GLS++LGITRK + ++I+ Y+  +PG++ YM+ +VR+AK+KGYV TL+ RRR LP
Sbjct  719  GISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELP  778

Query  774  EITSRNFNLRSFAERTAMNTPIQGTAADIIKKAMIEMDKRLKDENLQAKLLLQVHDELIF  833
            +I SRNFN+RSFAERTA+N+PIQG+AADI+K AMI++DK L+   ++AK+LLQVHDE+++
Sbjct  779  DINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVL  838

Query  834  EAPEEEIKILEKIVPEVMENALELEVPLKVDYSYGKTWYEAK  875
            E P++E+  + K+V + ME A++L VPL VD S G++WYEAK
Sbjct  839  EVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

227) polA in NC_014019


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  717 bits (2711),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 437/882 (50%), Positives = 654/882 (75%), Gaps = 15/882 (1%)

Query  3    QKLVLIDGNSIAYRAFFAL----PLLNNDKGIHTNAIYGFTTMLTRILEEEKPTHLLVAF  58
            +KL+LIDG+S+A+RAFFAL      ++N+ G+HTNAIYGF  ML +++   +PTH+LVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  59   DAGKTTFRHKTFTEYKGGRQKTPPELSEQFPFIRELLDAYGIKRYELPDYEADDIIGTLS  118
            DAGKTTFR   +++YK+GR KTP E+ EQF++IRE+L A GI  YEL +YEADDIIGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  119  KQAEKKGMA--VKVISGDKDLLQLVSEHVTVDITRKGITDVDSYTPAAIDEKYGITAAQI  176
            K AE+  ++  V ++SGDKDL+QL  E+  V+I++KG+++ + +TPA + EK G+T+ Q+
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  177  IDMKGLMGDSSDNIPGVPGVGEKTALKLLKEFETVENVLKSIDQVSGKKLKEKLEDNRES  236
            ID+K+LMGD SDNIPGV  +GEKT+LKLL EF ++E +   ID     K+KE+L ++R+ 
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRDQ  244

Query  237  AIMSKKLATIYCEAPLEVSVEDAKYDGFESSKVISLFKELGFNSLLAKFGesaeeeadfe  296
            A++SK LATI   +P+ ++++D  Y+G + + +  ++ E++F  L   ++    +E+   
Sbjct  245  AFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEPVAV  304

Query  297  eltfeIAQEVHDDMLTSEAALIVEGYEENYHHNQLLGFGISNKNGHYFIDKDTALSSSKF  356
                E++ +V  D++++E  +  E   +NYH++ ++GF+ ++ +  Y     + L++  F
Sbjct  305  ISYQEVT-NVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLATDSF  363

Query  357  KAWLEDGRVKKTVFNGKRTIVSLKWAGHEIKGIEHDVMIASYILNPAEANDDLATIAKLK  416
            K  ++      + ++ KR+ V L   G E+ +   D  +A+Y+L+  E +++L+TIA++ 
Sbjct  364  KQVFQKP---IATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVE-DNELSTIARIF  419

Query  417  GYHQVQSDEAVYGKGAKRSIAEAAQLAEHVIRKAAAVAYlkevlekelveNEQFELFEKL  476
                ++ D++VYGKGAKR++++   L EH+ RK   +   K  +   L  +EQ++L++++
Sbjct  420  TDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNI  479

Query  477  EMPLAIVLADMEYQGVKIDRARLDEMGEDLREQLEKIEAKIYEYAGQEFNINSPKQLGVV  536
            E+PLA VLA ME +G+K++RA L++M+E+ +  +E +   IY+ AGQEFNINSPKQLG +
Sbjct  480  ELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSI  539

Query  537  LFEKMQLP--VIKKTKTGYSTSADVLEQLASTHDIIPEILQYRQLGKLQSTYIEGLKKVI  594
            LFEKMQLP  + KKTKTGYST+ DVLE+LA+   I++ IL+YRQ+ KLQSTY+ GL+  I
Sbjct  540  LFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYI  599

Query  595  HESDGKVHTRFNQTLTQTGRLSSVDPNLQNIPIRLEEGKKIRGAFVPSQPDWLIFAADYS  654
              +DGK+HTR+ Q LTQTGRLSSVDPNLQNIPIRLE+G+ IR AF PS+ D +++++DYS
Sbjct  600  L-ADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYS  658

Query  655  QIELRVLAHIADDEKLIDAFKHDLDIHTKTAMDVFHVERE-EVTSNMRRQAKAVNFGIVY  713
            QIELRVLAHI++DE LI AF+++ DIHT TAM VF +++  +VT+N RR+AKAVNFGIVY
Sbjct  659  QIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVY  718

Query  714  GISDYGLSQSLGITRKAAATFIERYLKSFPGVQEYMDTIVRDAKEKGYVTTLLHRRRYLP  773
            GISD+GLS++LGITRK + ++I+ Y+  +PG++ YM+ +VR+AK+KGYV TL+ RRR LP
Sbjct  719  GISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELP  778

Query  774  EITSRNFNLRSFAERTAMNTPIQGTAADIIKKAMIEMDKRLKDENLQAKLLLQVHDELIF  833
            +I SRNFN+RSFAERTA+N+PIQG+AADI+K AMI++DK L+   ++AK+LLQVHDE+++
Sbjct  779  DINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVL  838

Query  834  EAPEEEIKILEKIVPEVMENALELEVPLKVDYSYGKTWYEAK  875
            E P++E+  + K+V + ME A++L VPL VD S G++WYEAK
Sbjct  839  EVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

228) A284_05335 in NC_020164


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  717 bits (2714),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 427/890 (48%), Positives = 654/890 (74%), Gaps = 29/890 (3%)

Query  2    NKLVLIDGNSLSFRAFYAL----PLLSNKAGIHTNAVYGFAMLLEKILKEEQPNHFLVAF  57
            NKL+LIDG+S++FRAF+AL      + N +G+HTNA+YGF ++L+ ++K  +P H LVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  58   DAGKTTFRHSKYSEYKGGRQKTPPELSEQFPYIRQLLDAYHIKRYELENYEADDIIGTLS  117
            DAGKTTFR   Y++YK+GR KTP E+ EQF+YIR++L A  I  YELE+YEADDIIGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  118  READKA--GFETIIITGDRDLTQLATDHVTIYYTKKGVTDVDHYTPEFIAEKYNGLTPNQ  175
            + A+++   F+  I++GD+DL QL+ ++  +  +KKGV++ +++TP ++ EK  GLTPNQ
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEK-MGLTPNQ  183

Query  176  IIDMKGLMGDTSDNIPGVAGVGEKTAIKLLNQFNTVEGVYDNIESVSGKKLKEKLENSKD  235
            +ID+K+LMGD SDNIPGV+ +GEKT++KLL++F ++EG+Y++I++    K+KE+L N +D
Sbjct  184  FIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRD  243

Query  236  DALMSKDLATINVESPIEVKLEDTKMDEHLDETEKIELFKKLEFNQLLAEIDSVEATQEQ  295
            +A++SK LATIN  SPI + L+D   +   D +   +++  ++F QL   + S  + +  
Sbjct  244  QAFLSKTLATINTASPITIGLDDIVYNGP-DVASLSQFYDEMDFVQLKKGLASQMPQEPV  302

Query  296  KDKTFEVESNFDHINFSDLDEATIHFELEDSNYLKDNILKFG------LYTGEHHVVINA  349
               +++  +N     FS   E  + FE    NY ++ I+ F+      +Y++ +  ++ +
Sbjct  303  AVISYQEVTNVSADLFSA--EDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLAT  360

Query  350  DEIKQFSDLVNWLENPNTAKTVYDAKKTYVVSHRLDIDIQNIQFDVMLSSYIIDPSRTID  409
            D +KQ       +++P ++   YD K++ V+  +L+I++    +D  L++Y++      +
Sbjct  361  DSFKQV------FQKPIAT---YDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-N  410

Query  410  DVNSVVSLYGQHYVQDNVTIYGKGKKHHVPEDEILNKHVASIIEAVSESKAEMQKQLKEY  469
            +++++  ++ +  ++++ T+YGKG K+ VP+ ++L  H+A  +  + +SK++M  +L   
Sbjct  411  ELSTIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAH  470

Query  470  NQESLLADLELPLAEILSEMEEIGIFTDVKDLQQMEKEIQEKLDVLIKNIHEAAGEEFNI  529
            +Q  L  ++ELPLA++L+ ME  GI  +   LQ+M  + +  ++ L ++I + AG+EFNI
Sbjct  471  EQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNI  530

Query  530  NSPKQLGVVLFETLELP--VIKKTKTGYSTAVDVLEQLQGQHPIIDYILEYRQLSKLQST  587
            NSPKQLG +LFE ++LP  + KKTKTGYSTAVDVLE+L    PI+  IL+YRQ++KLQST
Sbjct  531  NSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQST  590

Query  588  YVEGLQKVISDDHRIHTRFNQTLAQTGRLSSVDPNLQNIPIRLEEGRKIRKAFKPTSSDS  647
            YV GLQ  I  D +IHTR+ Q L+QTGRLSSVDPNLQNIPIRLE+GR IRKAF P+  D+
Sbjct  591  YVIGLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDA  650

Query  648  VILSADYSQIELRVLAHITQDESMKEAFINGHDIHTATAMKVFDVE-ADEVDSLMRRQAK  706
            V+LS+DYSQIELRVLAHI+ DE +  AF +G DIHT+TAM+VF+++ A +V +  RR+AK
Sbjct  651  VLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAK  710

Query  707  AVNFGIVYGISDYGLSQSLGITRKKAKAFIDDYLDSFPGVKQYMSDIVKDAKAQGFVETL  766
            AVNFGIVYGISD+GLS++LGITRK++K++ID Y++ +PG+K YM ++V++AK +G+VETL
Sbjct  711  AVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETL  770

Query  767  LHRRRYIPDITSRNFNLRSFAERTAMNTPIQGSAADIIKLAMVQFNKEVQHTDYHAKLLL  826
            + RRR +PDI SRNFN+RSFAERTA+N+PIQGSAADI+K+AM++++K +Q  +++AK+LL
Sbjct  771  FKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLL  830

Query  827  QVHDELIFEVPKDEVASFSKFVEEIMESALKLDVPLKVDSSYGATWYDAK  876
            QVHDE+++EVP+DE++++ K+V + ME+A+ L VPL VD S G +WY+AK
Sbjct  831  QVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

229) polA in NC_012659


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  716 bits (2709),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 446/885 (51%), Positives = 663/885 (75%), Gaps = 19/885 (2%)

Query  3    KKVVLVDGNNIAYRAFFAL----PLLNNDKGIHTNAIYGFTMMLMRILEEEKPTHMLVAF  58
            +K++L+DG+++A+RAFFAL      ++N+ G+HTNAIYGF +ML +++   +PTH+LVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  59   DAGKTTFRHKTYSEYKGGRQKTPPELSEQFPFIREMLDAFNVPRYELENYEADDIMGTLA  118
            DAGKTTFR   Y++YK+GR KTP E+ EQF++IREML A+ ++ YELE+YEADDI+GTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  119  K--EASEQGASVKVISGDKDLLQLVSDNTLVCIPRKGITEVDEYTKEALFEKYSLSPKQI  176
            K  E +E    V ++SGDKDL+QL  +NT+V I++KG++E +E+T   L EK +L+P+Q+
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  177  IDMKGLMGDQSDNIPGVPGVGEKTAIKLLTQFGTVEEVYENIDQVSGKKLKEKLEANKDQ  236
            ID+K+LMGD+SDNIPGV  +GEKT++KLL +FG++E +YE+ID     K+KE+L  ++DQ
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRDQ  244

Query  237  ALMSKDLATIITDAPITVNVDDMEYKGYEASDVIPMFENLGFTSLLNKLGVTPEETAPAE  296
            A++SK LATI T +PIT+ +DD+ Y+G + + +   +++++F  L + L+    + +   
Sbjct  245  AFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLA---SQMPQEP  301

Query  297  LDDITFDIVEEVTEEMLQQDSALIVEVQEDNYHKADIQGFGIQNENGCYFIQTDIAL-KS  355
            +  I+++ V +V+ +++  +  +  E   DNYH+  I GF+  + +  Y   TD++L  +
Sbjct  302  VAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIY-ASTDLSLLAT  360

Query  356  DAFKEWLADGEMRKYTFDAKRAIVALKWNGIDMQGIDFDLLIAAYLLDPADTDKDFRTVA  415
            D+FK+ + +  +  Y F  KR+ V L   GI++ +  +D  +A YLL   + D+++ T+A
Sbjct  361  DSFKQ-VFQKPIATYDF--KRSKVLLSHLGIELVAPSYDARLANYLLSTVE-DNELSTIA  416

Query  416  KMKETHAVKSDEEVYGKGAKRAVPELEIVAEHVARKVHVLYDVKQTFVEELEKNEQYELF  475
            ++    ++  D+ VYGKGAKRAVP+ +++ EH+ARKV VL D K   ++ L  +EQ +L+
Sbjct  417  RIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLY  476

Query  476  TELELPLARVLADMEVKGVKVDTERLRNMGEELAGRLKEMEQEIYKLAGTEFNINSPKQL  535
             ++ELPLA VLA ME+ G+KV+   L++M+E+    +  + QEIY +AG EFNINSPKQL
Sbjct  477  QNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQL  536

Query  536  GVILFENLNLP--VIKKTKTGYSTSADVLDKLMDHHEIIPNILHYRQLGKLNSTYIEGLL  593
            G ILFE+++LP  + KKTKTGYST+ DVL++L     I+++IL+YRQ+ KL+STY+ GL 
Sbjct  537  GSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQ  596

Query  594  KVVHEDSSKIHTRFNQVLTQTGRLSSTDPNLQNIPIRLEEGRKIRQAFVPSEEGWIMYAA  653
              +  D+ KIHTR+ Q LTQTGRLSS DPNLQNIPIRLE+GR IR+AF PS+E+ ++ ++
Sbjct  597  DYILADG-KIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSS  655

Query  654  DYSQIELRVLAHIANDKGLVEAFQHDMDIHTKTAMDVFGVEKD-EVTSNMRRQAKAVNFG  712
            DYSQIELRVLAHI+ D  L+ AF+++ DIHT TAM VFG++K  +VT+N RR+AKAVNFG
Sbjct  656  DYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFG  715

Query  713  IVYGISDYGLSQNLGITRKAAAEFIEKYLESFPGVQEYMDDIVKDAKQKGYVATLLNRRR  772
            IVYGISD+GLS+NLGITRK +  +I+ Y+E +PG++ YM+++V++AK+KGYV TL++RRR
Sbjct  716  IVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRR  775

Query  773  YIPEITSRNFNLRSFAERTAMNTPIQGTaadiikkamiimadRLEEEGLQARLLLQVHDE  832
             +P+I SRNFN+RSFAERTA+N+PIQG+AADI+K AMI +   L+  G++A++LLQVHDE
Sbjct  776  ELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDE  835

Query  833  LIFEApkeevekleklvpevMEHAIELAVPLKVDYSYGPTWYDAK  877
            +++E P++E+  + KLV + ME A++LAVPL VD S G +WY+AK
Sbjct  836  IVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

230) polA in NC_007530


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  716 bits (2709),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 446/885 (51%), Positives = 663/885 (75%), Gaps = 19/885 (2%)

Query  3    KKVVLVDGNNIAYRAFFAL----PLLNNDKGIHTNAIYGFTMMLMRILEEEKPTHMLVAF  58
            +K++L+DG+++A+RAFFAL      ++N+ G+HTNAIYGF +ML +++   +PTH+LVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  59   DAGKTTFRHKTYSEYKGGRQKTPPELSEQFPFIREMLDAFNVPRYELENYEADDIMGTLA  118
            DAGKTTFR   Y++YK+GR KTP E+ EQF++IREML A+ ++ YELE+YEADDI+GTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  119  K--EASEQGASVKVISGDKDLLQLVSDNTLVCIPRKGITEVDEYTKEALFEKYSLSPKQI  176
            K  E +E    V ++SGDKDL+QL  +NT+V I++KG++E +E+T   L EK +L+P+Q+
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  177  IDMKGLMGDQSDNIPGVPGVGEKTAIKLLTQFGTVEEVYENIDQVSGKKLKEKLEANKDQ  236
            ID+K+LMGD+SDNIPGV  +GEKT++KLL +FG++E +YE+ID     K+KE+L  ++DQ
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRDQ  244

Query  237  ALMSKDLATIITDAPITVNVDDMEYKGYEASDVIPMFENLGFTSLLNKLGVTPEETAPAE  296
            A++SK LATI T +PIT+ +DD+ Y+G + + +   +++++F  L + L+    + +   
Sbjct  245  AFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLA---SQMPQEP  301

Query  297  LDDITFDIVEEVTEEMLQQDSALIVEVQEDNYHKADIQGFGIQNENGCYFIQTDIAL-KS  355
            +  I+++ V +V+ +++  +  +  E   DNYH+  I GF+  + +  Y   TD++L  +
Sbjct  302  VAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIY-ASTDLSLLAT  360

Query  356  DAFKEWLADGEMRKYTFDAKRAIVALKWNGIDMQGIDFDLLIAAYLLDPADTDKDFRTVA  415
            D+FK+ + +  +  Y F  KR+ V L   GI++ +  +D  +A YLL   + D+++ T+A
Sbjct  361  DSFKQ-VFQKPIATYDF--KRSKVLLSHLGIELVAPSYDARLANYLLSTVE-DNELSTIA  416

Query  416  KMKETHAVKSDEEVYGKGAKRAVPELEIVAEHVARKVHVLYDVKQTFVEELEKNEQYELF  475
            ++    ++  D+ VYGKGAKRAVP+ +++ EH+ARKV VL D K   ++ L  +EQ +L+
Sbjct  417  RIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLY  476

Query  476  TELELPLARVLADMEVKGVKVDTERLRNMGEELAGRLKEMEQEIYKLAGTEFNINSPKQL  535
             ++ELPLA VLA ME+ G+KV+   L++M+E+    +  + QEIY +AG EFNINSPKQL
Sbjct  477  QNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQL  536

Query  536  GVILFENLNLP--VIKKTKTGYSTSADVLDKLMDHHEIIPNILHYRQLGKLNSTYIEGLL  593
            G ILFE+++LP  + KKTKTGYST+ DVL++L     I+++IL+YRQ+ KL+STY+ GL 
Sbjct  537  GSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQ  596

Query  594  KVVHEDSSKIHTRFNQVLTQTGRLSSTDPNLQNIPIRLEEGRKIRQAFVPSEEGWIMYAA  653
              +  D+ KIHTR+ Q LTQTGRLSS DPNLQNIPIRLE+GR IR+AF PS+E+ ++ ++
Sbjct  597  DYILADG-KIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSS  655

Query  654  DYSQIELRVLAHIANDKGLVEAFQHDMDIHTKTAMDVFGVEKD-EVTSNMRRQAKAVNFG  712
            DYSQIELRVLAHI+ D  L+ AF+++ DIHT TAM VFG++K  +VT+N RR+AKAVNFG
Sbjct  656  DYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFG  715

Query  713  IVYGISDYGLSQNLGITRKAAAEFIEKYLESFPGVQEYMDDIVKDAKQKGYVATLLNRRR  772
            IVYGISD+GLS+NLGITRK +  +I+ Y+E +PG++ YM+++V++AK+KGYV TL++RRR
Sbjct  716  IVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRR  775

Query  773  YIPEITSRNFNLRSFAERTAMNTPIQGTaadiikkamiimadRLEEEGLQARLLLQVHDE  832
             +P+I SRNFN+RSFAERTA+N+PIQG+AADI+K AMI +   L+  G++A++LLQVHDE
Sbjct  776  ELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDE  835

Query  833  LIFEApkeevekleklvpevMEHAIELAVPLKVDYSYGPTWYDAK  877
            +++E P++E+  + KLV + ME A++LAVPL VD S G +WY+AK
Sbjct  836  IVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

231) polA in NC_003997


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  716 bits (2709),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 446/885 (51%), Positives = 663/885 (75%), Gaps = 19/885 (2%)

Query  3    KKVVLVDGNNIAYRAFFAL----PLLNNDKGIHTNAIYGFTMMLMRILEEEKPTHMLVAF  58
            +K++L+DG+++A+RAFFAL      ++N+ G+HTNAIYGF +ML +++   +PTH+LVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  59   DAGKTTFRHKTYSEYKGGRQKTPPELSEQFPFIREMLDAFNVPRYELENYEADDIMGTLA  118
            DAGKTTFR   Y++YK+GR KTP E+ EQF++IREML A+ ++ YELE+YEADDI+GTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  119  K--EASEQGASVKVISGDKDLLQLVSDNTLVCIPRKGITEVDEYTKEALFEKYSLSPKQI  176
            K  E +E    V ++SGDKDL+QL  +NT+V I++KG++E +E+T   L EK +L+P+Q+
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  177  IDMKGLMGDQSDNIPGVPGVGEKTAIKLLTQFGTVEEVYENIDQVSGKKLKEKLEANKDQ  236
            ID+K+LMGD+SDNIPGV  +GEKT++KLL +FG++E +YE+ID     K+KE+L  ++DQ
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRDQ  244

Query  237  ALMSKDLATIITDAPITVNVDDMEYKGYEASDVIPMFENLGFTSLLNKLGVTPEETAPAE  296
            A++SK LATI T +PIT+ +DD+ Y+G + + +   +++++F  L + L+    + +   
Sbjct  245  AFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLA---SQMPQEP  301

Query  297  LDDITFDIVEEVTEEMLQQDSALIVEVQEDNYHKADIQGFGIQNENGCYFIQTDIAL-KS  355
            +  I+++ V +V+ +++  +  +  E   DNYH+  I GF+  + +  Y   TD++L  +
Sbjct  302  VAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIY-ASTDLSLLAT  360

Query  356  DAFKEWLADGEMRKYTFDAKRAIVALKWNGIDMQGIDFDLLIAAYLLDPADTDKDFRTVA  415
            D+FK+ + +  +  Y F  KR+ V L   GI++ +  +D  +A YLL   + D+++ T+A
Sbjct  361  DSFKQ-VFQKPIATYDF--KRSKVLLSHLGIELVAPSYDARLANYLLSTVE-DNELSTIA  416

Query  416  KMKETHAVKSDEEVYGKGAKRAVPELEIVAEHVARKVHVLYDVKQTFVEELEKNEQYELF  475
            ++    ++  D+ VYGKGAKRAVP+ +++ EH+ARKV VL D K   ++ L  +EQ +L+
Sbjct  417  RIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLY  476

Query  476  TELELPLARVLADMEVKGVKVDTERLRNMGEELAGRLKEMEQEIYKLAGTEFNINSPKQL  535
             ++ELPLA VLA ME+ G+KV+   L++M+E+    +  + QEIY +AG EFNINSPKQL
Sbjct  477  QNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQL  536

Query  536  GVILFENLNLP--VIKKTKTGYSTSADVLDKLMDHHEIIPNILHYRQLGKLNSTYIEGLL  593
            G ILFE+++LP  + KKTKTGYST+ DVL++L     I+++IL+YRQ+ KL+STY+ GL 
Sbjct  537  GSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQ  596

Query  594  KVVHEDSSKIHTRFNQVLTQTGRLSSTDPNLQNIPIRLEEGRKIRQAFVPSEEGWIMYAA  653
              +  D+ KIHTR+ Q LTQTGRLSS DPNLQNIPIRLE+GR IR+AF PS+E+ ++ ++
Sbjct  597  DYILADG-KIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSS  655

Query  654  DYSQIELRVLAHIANDKGLVEAFQHDMDIHTKTAMDVFGVEKD-EVTSNMRRQAKAVNFG  712
            DYSQIELRVLAHI+ D  L+ AF+++ DIHT TAM VFG++K  +VT+N RR+AKAVNFG
Sbjct  656  DYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFG  715

Query  713  IVYGISDYGLSQNLGITRKAAAEFIEKYLESFPGVQEYMDDIVKDAKQKGYVATLLNRRR  772
            IVYGISD+GLS+NLGITRK +  +I+ Y+E +PG++ YM+++V++AK+KGYV TL++RRR
Sbjct  716  IVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRR  775

Query  773  YIPEITSRNFNLRSFAERTAMNTPIQGTaadiikkamiimadRLEEEGLQARLLLQVHDE  832
             +P+I SRNFN+RSFAERTA+N+PIQG+AADI+K AMI +   L+  G++A++LLQVHDE
Sbjct  776  ELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDE  835

Query  833  LIFEApkeevekleklvpevMEHAIELAVPLKVDYSYGPTWYDAK  877
            +++E P++E+  + KLV + ME A++LAVPL VD S G +WY+AK
Sbjct  836  IVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

232) polA in NC_012581


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  716 bits (2709),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 446/885 (51%), Positives = 663/885 (75%), Gaps = 19/885 (2%)

Query  3    KKVVLVDGNNIAYRAFFAL----PLLNNDKGIHTNAIYGFTMMLMRILEEEKPTHMLVAF  58
            +K++L+DG+++A+RAFFAL      ++N+ G+HTNAIYGF +ML +++   +PTH+LVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  59   DAGKTTFRHKTYSEYKGGRQKTPPELSEQFPFIREMLDAFNVPRYELENYEADDIMGTLA  118
            DAGKTTFR   Y++YK+GR KTP E+ EQF++IREML A+ ++ YELE+YEADDI+GTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  119  K--EASEQGASVKVISGDKDLLQLVSDNTLVCIPRKGITEVDEYTKEALFEKYSLSPKQI  176
            K  E +E    V ++SGDKDL+QL  +NT+V I++KG++E +E+T   L EK +L+P+Q+
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  177  IDMKGLMGDQSDNIPGVPGVGEKTAIKLLTQFGTVEEVYENIDQVSGKKLKEKLEANKDQ  236
            ID+K+LMGD+SDNIPGV  +GEKT++KLL +FG++E +YE+ID     K+KE+L  ++DQ
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRDQ  244

Query  237  ALMSKDLATIITDAPITVNVDDMEYKGYEASDVIPMFENLGFTSLLNKLGVTPEETAPAE  296
            A++SK LATI T +PIT+ +DD+ Y+G + + +   +++++F  L + L+    + +   
Sbjct  245  AFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLA---SQMPQEP  301

Query  297  LDDITFDIVEEVTEEMLQQDSALIVEVQEDNYHKADIQGFGIQNENGCYFIQTDIAL-KS  355
            +  I+++ V +V+ +++  +  +  E   DNYH+  I GF+  + +  Y   TD++L  +
Sbjct  302  VAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIY-ASTDLSLLAT  360

Query  356  DAFKEWLADGEMRKYTFDAKRAIVALKWNGIDMQGIDFDLLIAAYLLDPADTDKDFRTVA  415
            D+FK+ + +  +  Y F  KR+ V L   GI++ +  +D  +A YLL   + D+++ T+A
Sbjct  361  DSFKQ-VFQKPIATYDF--KRSKVLLSHLGIELVAPSYDARLANYLLSTVE-DNELSTIA  416

Query  416  KMKETHAVKSDEEVYGKGAKRAVPELEIVAEHVARKVHVLYDVKQTFVEELEKNEQYELF  475
            ++    ++  D+ VYGKGAKRAVP+ +++ EH+ARKV VL D K   ++ L  +EQ +L+
Sbjct  417  RIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLY  476

Query  476  TELELPLARVLADMEVKGVKVDTERLRNMGEELAGRLKEMEQEIYKLAGTEFNINSPKQL  535
             ++ELPLA VLA ME+ G+KV+   L++M+E+    +  + QEIY +AG EFNINSPKQL
Sbjct  477  QNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQL  536

Query  536  GVILFENLNLP--VIKKTKTGYSTSADVLDKLMDHHEIIPNILHYRQLGKLNSTYIEGLL  593
            G ILFE+++LP  + KKTKTGYST+ DVL++L     I+++IL+YRQ+ KL+STY+ GL 
Sbjct  537  GSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQ  596

Query  594  KVVHEDSSKIHTRFNQVLTQTGRLSSTDPNLQNIPIRLEEGRKIRQAFVPSEEGWIMYAA  653
              +  D+ KIHTR+ Q LTQTGRLSS DPNLQNIPIRLE+GR IR+AF PS+E+ ++ ++
Sbjct  597  DYILADG-KIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSS  655

Query  654  DYSQIELRVLAHIANDKGLVEAFQHDMDIHTKTAMDVFGVEKD-EVTSNMRRQAKAVNFG  712
            DYSQIELRVLAHI+ D  L+ AF+++ DIHT TAM VFG++K  +VT+N RR+AKAVNFG
Sbjct  656  DYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFG  715

Query  713  IVYGISDYGLSQNLGITRKAAAEFIEKYLESFPGVQEYMDDIVKDAKQKGYVATLLNRRR  772
            IVYGISD+GLS+NLGITRK +  +I+ Y+E +PG++ YM+++V++AK+KGYV TL++RRR
Sbjct  716  IVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRR  775

Query  773  YIPEITSRNFNLRSFAERTAMNTPIQGTaadiikkamiimadRLEEEGLQARLLLQVHDE  832
             +P+I SRNFN+RSFAERTA+N+PIQG+AADI+K AMI +   L+  G++A++LLQVHDE
Sbjct  776  ELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDE  835

Query  833  LIFEApkeevekleklvpevMEHAIELAVPLKVDYSYGPTWYDAK  877
            +++E P++E+  + KLV + ME A++LAVPL VD S G +WY+AK
Sbjct  836  IVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

233) H9401_4610 in NC_017729


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  716 bits (2710),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 446/885 (51%), Positives = 663/885 (75%), Gaps = 19/885 (2%)

Query  17   KKVVLVDGNNIAYRAFFAL----PLLNNDKGIHTNAIYGFTMMLMRILEEEKPTHMLVAF  72
            +K++L+DG+++A+RAFFAL      ++N+ G+HTNAIYGF +ML +++   +PTH+LVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  73   DAGKTTFRHKTYSEYKGGRQKTPPELSEQFPFIREMLDAFNVPRYELENYEADDIMGTLA  132
            DAGKTTFR   Y++YK+GR KTP E+ EQF++IREML A+ ++ YELE+YEADDI+GTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  133  K--EASEQGASVKVISGDKDLLQLVSDNTLVCIPRKGITEVDEYTKEALFEKYSLSPKQI  190
            K  E +E    V ++SGDKDL+QL  +NT+V I++KG++E +E+T   L EK +L+P+Q+
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  191  IDMKGLMGDQSDNIPGVPGVGEKTAIKLLTQFGTVEEVYENIDQVSGKKLKEKLEANKDQ  250
            ID+K+LMGD+SDNIPGV  +GEKT++KLL +FG++E +YE+ID     K+KE+L  ++DQ
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRDQ  244

Query  251  ALMSKDLATIITDAPITVNVDDMEYKGYEASDVIPMFENLGFTSLLNKLGVTPEETAPAE  310
            A++SK LATI T +PIT+ +DD+ Y+G + + +   +++++F  L + L+    + +   
Sbjct  245  AFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLA---SQMPQEP  301

Query  311  LDDITFDIVEEVTEEMLQQDSALIVEVQEDNYHKADIQGFGIQNENGCYFIQTDIAL-KS  369
            +  I+++ V +V+ +++  +  +  E   DNYH+  I GF+  + +  Y   TD++L  +
Sbjct  302  VAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIY-ASTDLSLLAT  360

Query  370  DAFKEWLADGEMRKYTFDAKRAIVALKWNGIDMQGIDFDLLIAAYLLDPADTDKDFRTVA  429
            D+FK+ + +  +  Y F  KR+ V L   GI++ +  +D  +A YLL   + D+++ T+A
Sbjct  361  DSFKQ-VFQKPIATYDF--KRSKVLLSHLGIELVAPSYDARLANYLLSTVE-DNELSTIA  416

Query  430  KMKETHAVKSDEEVYGKGAKRAVPELEIVAEHVARKVHVLYDVKQTFVEELEKNEQYELF  489
            ++    ++  D+ VYGKGAKRAVP+ +++ EH+ARKV VL D K   ++ L  +EQ +L+
Sbjct  417  RIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLY  476

Query  490  TELELPLARVLADMEVKGVKVDTERLRNMGEELAGRLKEMEQEIYKLAGTEFNINSPKQL  549
             ++ELPLA VLA ME+ G+KV+   L++M+E+    +  + QEIY +AG EFNINSPKQL
Sbjct  477  QNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQL  536

Query  550  GVILFENLNLP--VIKKTKTGYSTSADVLDKLMDHHEIIPNILHYRQLGKLNSTYIEGLL  607
            G ILFE+++LP  + KKTKTGYST+ DVL++L     I+++IL+YRQ+ KL+STY+ GL 
Sbjct  537  GSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQ  596

Query  608  KVVHEDSSKIHTRFNQVLTQTGRLSSTDPNLQNIPIRLEEGRKIRQAFVPSEEGWIMYAA  667
              +  D+ KIHTR+ Q LTQTGRLSS DPNLQNIPIRLE+GR IR+AF PS+E+ ++ ++
Sbjct  597  DYILADG-KIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSS  655

Query  668  DYSQIELRVLAHIANDKGLVEAFQHDMDIHTKTAMDVFGVEKD-EVTSNMRRQAKAVNFG  726
            DYSQIELRVLAHI+ D  L+ AF+++ DIHT TAM VFG++K  +VT+N RR+AKAVNFG
Sbjct  656  DYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFG  715

Query  727  IVYGISDYGLSQNLGITRKAAAEFIEKYLESFPGVQEYMDDIVKDAKQKGYVATLLNRRR  786
            IVYGISD+GLS+NLGITRK +  +I+ Y+E +PG++ YM+++V++AK+KGYV TL++RRR
Sbjct  716  IVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRR  775

Query  787  YIPEITSRNFNLRSFAERTAMNTPIQGTaadiikkamiimadRLEEEGLQARLLLQVHDE  846
             +P+I SRNFN+RSFAERTA+N+PIQG+AADI+K AMI +   L+  G++A++LLQVHDE
Sbjct  776  ELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDE  835

Query  847  LIFEApkeevekleklvpevMEHAIELAVPLKVDYSYGPTWYDAK  891
            +++E P++E+  + KLV + ME A++LAVPL VD S G +WY+AK
Sbjct  836  IVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

234) BAS4482 in NC_005945


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  716 bits (2710),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 446/885 (51%), Positives = 663/885 (75%), Gaps = 19/885 (2%)

Query  17   KKVVLVDGNNIAYRAFFAL----PLLNNDKGIHTNAIYGFTMMLMRILEEEKPTHMLVAF  72
            +K++L+DG+++A+RAFFAL      ++N+ G+HTNAIYGF +ML +++   +PTH+LVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  73   DAGKTTFRHKTYSEYKGGRQKTPPELSEQFPFIREMLDAFNVPRYELENYEADDIMGTLA  132
            DAGKTTFR   Y++YK+GR KTP E+ EQF++IREML A+ ++ YELE+YEADDI+GTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  133  K--EASEQGASVKVISGDKDLLQLVSDNTLVCIPRKGITEVDEYTKEALFEKYSLSPKQI  190
            K  E +E    V ++SGDKDL+QL  +NT+V I++KG++E +E+T   L EK +L+P+Q+
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  191  IDMKGLMGDQSDNIPGVPGVGEKTAIKLLTQFGTVEEVYENIDQVSGKKLKEKLEANKDQ  250
            ID+K+LMGD+SDNIPGV  +GEKT++KLL +FG++E +YE+ID     K+KE+L  ++DQ
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRDQ  244

Query  251  ALMSKDLATIITDAPITVNVDDMEYKGYEASDVIPMFENLGFTSLLNKLGVTPEETAPAE  310
            A++SK LATI T +PIT+ +DD+ Y+G + + +   +++++F  L + L+    + +   
Sbjct  245  AFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLA---SQMPQEP  301

Query  311  LDDITFDIVEEVTEEMLQQDSALIVEVQEDNYHKADIQGFGIQNENGCYFIQTDIAL-KS  369
            +  I+++ V +V+ +++  +  +  E   DNYH+  I GF+  + +  Y   TD++L  +
Sbjct  302  VAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIY-ASTDLSLLAT  360

Query  370  DAFKEWLADGEMRKYTFDAKRAIVALKWNGIDMQGIDFDLLIAAYLLDPADTDKDFRTVA  429
            D+FK+ + +  +  Y F  KR+ V L   GI++ +  +D  +A YLL   + D+++ T+A
Sbjct  361  DSFKQ-VFQKPIATYDF--KRSKVLLSHLGIELVAPSYDARLANYLLSTVE-DNELSTIA  416

Query  430  KMKETHAVKSDEEVYGKGAKRAVPELEIVAEHVARKVHVLYDVKQTFVEELEKNEQYELF  489
            ++    ++  D+ VYGKGAKRAVP+ +++ EH+ARKV VL D K   ++ L  +EQ +L+
Sbjct  417  RIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLY  476

Query  490  TELELPLARVLADMEVKGVKVDTERLRNMGEELAGRLKEMEQEIYKLAGTEFNINSPKQL  549
             ++ELPLA VLA ME+ G+KV+   L++M+E+    +  + QEIY +AG EFNINSPKQL
Sbjct  477  QNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQL  536

Query  550  GVILFENLNLP--VIKKTKTGYSTSADVLDKLMDHHEIIPNILHYRQLGKLNSTYIEGLL  607
            G ILFE+++LP  + KKTKTGYST+ DVL++L     I+++IL+YRQ+ KL+STY+ GL 
Sbjct  537  GSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQ  596

Query  608  KVVHEDSSKIHTRFNQVLTQTGRLSSTDPNLQNIPIRLEEGRKIRQAFVPSEEGWIMYAA  667
              +  D+ KIHTR+ Q LTQTGRLSS DPNLQNIPIRLE+GR IR+AF PS+E+ ++ ++
Sbjct  597  DYILADG-KIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSS  655

Query  668  DYSQIELRVLAHIANDKGLVEAFQHDMDIHTKTAMDVFGVEKD-EVTSNMRRQAKAVNFG  726
            DYSQIELRVLAHI+ D  L+ AF+++ DIHT TAM VFG++K  +VT+N RR+AKAVNFG
Sbjct  656  DYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFG  715

Query  727  IVYGISDYGLSQNLGITRKAAAEFIEKYLESFPGVQEYMDDIVKDAKQKGYVATLLNRRR  786
            IVYGISD+GLS+NLGITRK +  +I+ Y+E +PG++ YM+++V++AK+KGYV TL++RRR
Sbjct  716  IVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRR  775

Query  787  YIPEITSRNFNLRSFAERTAMNTPIQGTaadiikkamiimadRLEEEGLQARLLLQVHDE  846
             +P+I SRNFN+RSFAERTA+N+PIQG+AADI+K AMI +   L+  G++A++LLQVHDE
Sbjct  776  ELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDE  835

Query  847  LIFEApkeevekleklvpevMEHAIELAVPLKVDYSYGPTWYDAK  891
            +++E P++E+  + KLV + ME A++LAVPL VD S G +WY+AK
Sbjct  836  IVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

235) polA in NC_011773


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  716 bits (2709),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 446/885 (51%), Positives = 663/885 (75%), Gaps = 19/885 (2%)

Query  3    KKVVLVDGNNIAYRAFFAL----PLLNNDKGIHTNAIYGFTMMLMRILEEEKPTHMLVAF  58
            +K++L+DG+++A+RAFFAL      ++N+ G+HTNAIYGF +ML +++   +PTH+LVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  59   DAGKTTFRHKTYSEYKGGRQKTPPELSEQFPFIREMLDAFNVPRYELENYEADDIMGTLA  118
            DAGKTTFR   Y++YK+GR KTP E+ EQF++IREML A+ ++ YELE+YEADDI+GTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  119  K--EASEQGASVKVISGDKDLLQLVSDNTLVCIPRKGITEVDEYTKEALFEKYSLSPKQI  176
            K  E +E    V ++SGDKDL+QL  +NT+V I++KG++E +E+T   L EK +L+P+Q+
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  177  IDMKGLMGDQSDNIPGVPGVGEKTAIKLLTQFGTVEEVYENIDQVSGKKLKEKLEANKDQ  236
            ID+K+LMGD+SDNIPGV  +GEKT++KLL +FG++E +YE+ID     K+KE+L  ++DQ
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRDQ  244

Query  237  ALMSKDLATIITDAPITVNVDDMEYKGYEASDVIPMFENLGFTSLLNKLGVTPEETAPAE  296
            A++SK LATI T +PIT+ +DD+ Y+G + + +   +++++F  L + L+    + +   
Sbjct  245  AFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLA---SQMPQEP  301

Query  297  LDDITFDIVEEVTEEMLQQDSALIVEVQEDNYHKADIQGFGIQNENGCYFIQTDIAL-KS  355
            +  I+++ V +V+ +++  +  +  E   DNYH+  I GF+  + +  Y   TD++L  +
Sbjct  302  VAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIY-ASTDLSLLAT  360

Query  356  DAFKEWLADGEMRKYTFDAKRAIVALKWNGIDMQGIDFDLLIAAYLLDPADTDKDFRTVA  415
            D+FK+ + +  +  Y F  KR+ V L   GI++ +  +D  +A YLL   + D+++ T+A
Sbjct  361  DSFKQ-VFQKPIATYDF--KRSKVLLSHLGIELVAPSYDARLANYLLSTVE-DNELSTIA  416

Query  416  KMKETHAVKSDEEVYGKGAKRAVPELEIVAEHVARKVHVLYDVKQTFVEELEKNEQYELF  475
            ++    ++  D+ VYGKGAKRAVP+ +++ EH+ARKV VL D K   ++ L  +EQ +L+
Sbjct  417  RIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLY  476

Query  476  TELELPLARVLADMEVKGVKVDTERLRNMGEELAGRLKEMEQEIYKLAGTEFNINSPKQL  535
             ++ELPLA VLA ME+ G+KV+   L++M+E+    +  + QEIY +AG EFNINSPKQL
Sbjct  477  QNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQL  536

Query  536  GVILFENLNLP--VIKKTKTGYSTSADVLDKLMDHHEIIPNILHYRQLGKLNSTYIEGLL  593
            G ILFE+++LP  + KKTKTGYST+ DVL++L     I+++IL+YRQ+ KL+STY+ GL 
Sbjct  537  GSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQ  596

Query  594  KVVHEDSSKIHTRFNQVLTQTGRLSSTDPNLQNIPIRLEEGRKIRQAFVPSEEGWIMYAA  653
              +  D+ KIHTR+ Q LTQTGRLSS DPNLQNIPIRLE+GR IR+AF PS+E+ ++ ++
Sbjct  597  DYILADG-KIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSS  655

Query  654  DYSQIELRVLAHIANDKGLVEAFQHDMDIHTKTAMDVFGVEKD-EVTSNMRRQAKAVNFG  712
            DYSQIELRVLAHI+ D  L+ AF+++ DIHT TAM VFG++K  +VT+N RR+AKAVNFG
Sbjct  656  DYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFG  715

Query  713  IVYGISDYGLSQNLGITRKAAAEFIEKYLESFPGVQEYMDDIVKDAKQKGYVATLLNRRR  772
            IVYGISD+GLS+NLGITRK +  +I+ Y+E +PG++ YM+++V++AK+KGYV TL++RRR
Sbjct  716  IVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRR  775

Query  773  YIPEITSRNFNLRSFAERTAMNTPIQGTaadiikkamiimadRLEEEGLQARLLLQVHDE  832
             +P+I SRNFN+RSFAERTA+N+PIQG+AADI+K AMI +   L+  G++A++LLQVHDE
Sbjct  776  ELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDE  835

Query  833  LIFEApkeevekleklvpevMEHAIELAVPLKVDYSYGPTWYDAK  877
            +++E P++E+  + KLV + ME A++LAVPL VD S G +WY+AK
Sbjct  836  IVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

236) BC4587 in NC_004722


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  716 bits (2710),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 445/885 (51%), Positives = 662/885 (75%), Gaps = 19/885 (2%)

Query  17   KKVVLVDGNNIAYRAFFAL----PLLNNDKGIHTNAIYGFTMMLMRILEEEKPTHMLVAF  72
            +K++L+DG+++A+RAFFAL      ++N+ G+HTNAIYGF +ML +++   +PTH+LVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  73   DAGKTTFRHKTYSEYKGGRQKTPPELSEQFPFIREMLDAFNVPRYELENYEADDIMGTLA  132
            DAGKTTFR   Y++YK+GR KTP E+ EQF++IREML A+ ++ YELE+YEADDI+GTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  133  K--EASEQGASVKVISGDKDLLQLVSDNTLVCIPRKGITEVDEYTKEALFEKYSLSPKQI  190
            K  E +E    V ++SGDKDL+QL  +NT+V I++KG++E +E+T   L EK +L+P+Q+
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  191  IDMKGLMGDQSDNIPGVPGVGEKTAIKLLTQFGTVEEVYENLDQVSGkklkekleenkeQ  250
            ID+K+LMGD+SDNIPGV  +GEKT++KLL +FG++E +YE++D     K+KE+L ++++Q
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRDQ  244

Query  251  ALMSKDLATIITDAPITVHVDDMAYKGYEASDVIPMFESLGFTSLLNKLGVTPEETAPAE  310
            A++SK LATI T +PIT+ +DD+ Y+G + + +   ++ ++F  L + L+    + +   
Sbjct  245  AFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLA---SQMPQEP  301

Query  311  LDDITFDIVEEVTEEMLQQDSALIVEVQEDNYHKADIQGFGIQNENGCYFIQTDIAL-KS  369
            +  I+++ V +V+ +++  +  +  E   DNYH+  I GF+  + +  Y   TD++L  +
Sbjct  302  VAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIY-ASTDLSLLAT  360

Query  370  DAFKEWLADGEMRKHTFDAKRAIVALKWNGIDMQGIDFDLLIAAYLLDPADTDKDFCTVA  429
            D+FK+ +   +    T+D KR+ V L   GI++ +  +D  +A YLL   + D+++ T+A
Sbjct  361  DSFKQVF---QKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVE-DNELSTIA  416

Query  430  KMKETHAVKSDEEVYGKGAKRAVPELKVVAEHVARKVHVLYDVKQTFVEELKKNEQYELF  489
            ++    ++  D+ VYGKGAKRAVP+  V+ EH+ARKV VL D K   ++ L  +EQ +L+
Sbjct  417  RIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLY  476

Query  490  TELELPLARVLADMEVKGVKVDTERLRNMGEELAGRLKEMEQEIYKLAGTEFNINSPKQL  549
             ++ELPLA VLA ME+ G+KV+   L++M+E+    +  + QEIY +AG EFNINSPKQL
Sbjct  477  QNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQL  536

Query  550  GVILFENLNLP--VIKKTKTGYSTSADVLDKLMNHHEIIPNILHYRQLGKLNSTYIEGLL  607
            G ILFE+++LP  + KKTKTGYST+ DVL++L     I+++IL+YRQ+ KL+STY+ GL 
Sbjct  537  GSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQ  596

Query  608  KVVHEDSSKIHTRFNQVLTQTGRLSSTDPNLQNIPIRLEEGRKIRQAFVPSEEGWIMYAA  667
              +  D+ KIHTR+ Q LTQTGRLSS DPNLQNIPIRLE+GR IR+AF PS+E+ ++ ++
Sbjct  597  DYILADG-KIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSS  655

Query  668  DYSQIELRVLAHIANDKGLVEAFQHDMDIHTKTAMDVFGVEKD-EVTSNMRRQAKAVNFG  726
            DYSQIELRVLAHI+ D  L+ AF+++ DIHT TAM VFG++K  +VT+N RR+AKAVNFG
Sbjct  656  DYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFG  715

Query  727  IVYGISDYGLSQNLGITRKAAAEFIEKYLESFPGVQEYMEDIVKDAKQKGYVATLLNRRR  786
            IVYGISD+GLS+NLGITRK +  +I+ Y+E +PG++ YME++V++AK+KGYV TL++RRR
Sbjct  716  IVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRR  775

Query  787  YIPEITSRNFNLRSFAERTAMNTPIQGTaadiikkamiimadRLEEEGLQARLLLQVHDE  846
             +P+I SRNFN+RSFAERTA+N+PIQG+AADI+K AMI +   L+  G++A++LLQVHDE
Sbjct  776  ELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDE  835

Query  847  LIFEAPKEEIEKLEQLVPEVMEHAIELAVPLKVDYSYGPTWYDAK  891
            +++E P++E+  + +LV + ME A++LAVPL VD S G +WY+AK
Sbjct  836  IVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

237) MC28_3865 in NC_018693


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  716 bits (2707),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 448/885 (51%), Positives = 666/885 (76%), Gaps = 19/885 (2%)

Query  16   KKVVLVDGNNIAYRAFFAL----PLLNNDKGIHTNAIYGFTMMLMRILEEEKPTHMLVAF  71
            +K++L+DG+++A+RAFFAL      ++N+ G+HTNAIYGF +ML +++   +PTH+LVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  72   DAGKTTFRHKTYSEYKGGRQKTPPELSEQFPFIREMLDAFNVPRYELENYEADDIMGTLA  131
            DAGKTTFR   Y++YK+GR KTP E+ EQF++IREML A+ ++ YELE+YEADDI+GTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  132  K--EASEQGFHVKVISGDKDLLQLVSDNTLVCIPRKGITEVDEYTKEALFEKYSLSPKQI  189
            K  E +E  F+V ++SGDKDL+QL  +NT+V I++KG++E +E+T   L EK +L+P+Q+
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  190  IDMKGLMGDQSDNIPGVPGVGEKTAIKLLTQFETVEAVYENIDQVSGkklkekleankeq  249
            ID+K+LMGD+SDNIPGV  +GEKT++KLL +F ++E++YE+ID     K+KE+L  +++Q
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRDQ  244

Query  250  alMSKDLATIITDAPITVHVDDMEYKGYEASDVIPMFENLGFTSLLNKLGVTPEETAPAE  309
            A++SK LATI T +PIT+ +DD+ Y+G + + +   +++++F  L + L+    + +   
Sbjct  245  AFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLA---SQMPQEP  301

Query  310  LDDITFDIVEEVTEEMLQQDSALIVEVQEDNYHKADIQGFGIQNENGCYFIQTDIAL-AS  368
            +  I+++ V +V+ +++  +  +  E   DNYH+  I GF+  + +  Y   TD++L A+
Sbjct  302  VAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIY-ASTDLSLLAT  360

Query  369  EAFKAWLANGEMRKHTFDAKRAIVALKWKGIDIQGIDFDLLIAAYLLDPADTDKDFRTVA  428
            ++FK  +   +    T+D KR+ V L   GI++ +  +D  +A YLL   + D+++ T+A
Sbjct  361  DSFKQVF---QKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVE-DNELSTIA  416

Query  429  KMKETHAVKSDEEVYGKGAKRAVPELEVVAEHVARKVHVLYDVKQTFLEELKKNEQYELF  488
            ++    ++  D+ VYGKGAKRAVP+ +V+ EH+ARKV VL D K   L+ L  +EQ +L+
Sbjct  417  RIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLY  476

Query  489  TELELPLARVLADMEVKGVKVDTERLRNMGEELAGRLKEMEQEIYKLAGTEFNINSPKQL  548
             ++ELPLA VLA ME+ G+KV+   L++M+E+    +  + QEIY +AG EFNINSPKQL
Sbjct  477  QNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQL  536

Query  549  GVILFENLNLP--VVKKTKTGYSTSADVLDKLMNHHEIIPNILHYRQLGKLNSTYIEGLL  606
            G ILFE+++LP  + KKTKTGYST+ DVL++L     I+++IL+YRQ+ KL+STY+ GL 
Sbjct  537  GSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQ  596

Query  607  KVVHEDSSKIHTRFNQVLTQTGRLSSTDPNLQNIPIRLEEGRKIRQAFVPSEEGWIMYAA  666
              +  D+ KIHTR+ Q LTQTGRLSS DPNLQNIPIRLE+GR IR+AF PS+E+ ++ ++
Sbjct  597  DYILADG-KIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSS  655

Query  667  DYSQIELRVLAHIANDKGLVEAFQHDMDIHTKTAMDVFDVGKD-EVTSNMRRQAKAVNFG  725
            DYSQIELRVLAHI+ D  L+ AF+++ DIHT TAM VF+++K  +VT+N RR+AKAVNFG
Sbjct  656  DYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFG  715

Query  726  IVYGISDYGLSQNLGITRKAAAEFIEKYLESFPGVQEYMDDIVKDAKQKGYVATLLNRRR  785
            IVYGISD+GLS+NLGITRK +  +I+ Y+E +PG++ YM+++V++AK+KGYV TL++RRR
Sbjct  716  IVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRR  775

Query  786  YIPEITSRNFNLRSFAERTAMNTPIQGSaadiikiamiimadRLEEEGLQARLLLQVHDE  845
             +P+I SRNFN+RSFAERTA+N+PIQGSAADI+KIAMI +   L+  G++A++LLQVHDE
Sbjct  776  ELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDE  835

Query  846  LIFEAPKEEIEKLEKLVPEVMEHAIELAVPLKVDYSYGPTWYDAK  890
            +++E P++E+  + KLV + ME A++LAVPL VD S G +WY+AK
Sbjct  836  IVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

238) polA in NC_010471


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  715 bits (2703),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 457/896 (52%), Positives = 653/896 (73%), Gaps = 25/896 (2%)

Query  3    KKLLLIDGNSLAFRAFYAMYNQLDRMISHKGLHTNALVAFNNFLDQIVDPMQPDLAVVAW  62
            +KLLLIDG+S+AFRAF+A+YNQ+DR  +H GLHTNA+ +F+  LD+++  ++P   +VA 
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  63   DAGSGKTTFRGELFSEYKDGRSKAPSEFTEQFPYLREMVALHGLRNYEQPGLEADDIIGT  122
            DAG  KTTFR E++++YK GR+K+P EF EQF+Y+REM++  G+  YE    EADDIIGT
Sbjct  65   DAG--KTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGT  122

Query  123  FSRMGEQAG--YNVIIVTGDQDLTQLATDNITVNVTKKGVTEIEAFTPDYIMEKFELTPS  180
            + +M+E++   ++V IV+GD+DL QL+ +N  V+++KKGV+E+E FTP Y+MEK  LTP+
Sbjct  123  LDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPN  182

Query  181  QIIEKKALTGDTSDNYPGVTKIGEKTALKLLKTYHDIDNLYRHIDDMKPSKMKENLISDQ  240
            Q+I+ KAL GD SDN PGVTKIGEKT+LKLL  +  ++ +Y HID+ K SKMKENLI+D+
Sbjct  183  QFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDR  242

Query  241  ASAFRARQlatiltdatldlplEELEYRGIDYDKLVPFYENIDFKKQLAKIKASQKSGQL  300
              AF ++ LATI T + + + L+++ Y G D   L  FY+++DF  QL K  ASQ + + 
Sbjct  243  DQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFV-QLKKGLASQMPQE-  300

Query  301  VSHNQSTERPLSVVTLNENNLRAIAMMVDKVAVHIEMSGSNYHTADMIGFVIGNPATGYY  360
                     P++V++ +E    +  +        +E    NYH   +IGF  G+ +   Y
Sbjct  301  ---------PVAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGH-GEQIY  350

Query  361  ASRDMSLLQKPELRAVIENGDIKKNVFNVKAQLILFKRLGLTLKGAQFDFLLVAYLLDTT  420
            AS D+SLL    ++ V+++       ++ K   +L+ +LG+ L ++ +D  L  YLL T 
Sbjct  351  ASTDLSLLATDSFKQVFQKP---IATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTV  407

Query  421  DNDNEMSTLAQRF-DVYLTEDEEIYGKGAKYAVPDDEELVLMHLAHKADALIQLEMPALS  479
            + DNE+ST+A+ F D+ L ED+ +YGKGAK AVPD + L L HLA+K   L++     L 
Sbjct  408  E-DNELSTIARIFTDISLEEDDTVYGKGAKRAVPDKDVL-LEHLARKVKVLLDSKSQMLD  465

Query  480  ALQSHQQTHLYTEIELPLAHVLAEMEYQGFKIDRKRLQVIGEDLEARIHTIEEAIYLEAG  539
             L +H+Q +LY +IELPLA+VLA ME +G+K++R  LQ ++E+    I+++ + IY  AG
Sbjct  466  KLTAHEQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAG  525

Query  540  EKFNLNSPKQLGILLFEKMGLPI--IKKTKTGYSTAVDVLEKLASQAPIVEHILQYRQLA  597
            + FN+NSPKQLG +LFEKM LP+   KKTKTGYSTAVDVLE+LA+ APIV  IL+YRQ++
Sbjct  526  QEFNINSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQIT  585

Query  598  KIKSTYVEGLLAVVHTEDSKIHTRFLQTLTQTGRLSSVDPNLQNIPMRTEEGRQIRRAFV  657
            K++STYV GL   + + D+KIHTR++Q LTQTGRLSSVDPNLQNIP+R E+GR IR+AF 
Sbjct  586  KLQSTYVIGLQDYILA-DGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFT  644

Query  658  PSQPNWQIFGADYSQIELRVLAHITGDQNMQRAFLNGEDIHAETARAVFGLDNNAPVDPL  717
            PS+ +  ++++DYSQIELRVLAHI+GD+++  AF +G DIH+ TA  VFG+D+ A V + 
Sbjct  645  PSHEDAVLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTAN  704

Query  718  MRRTAKAVNFGIVYGISDYGLSNNLGISRAEAKRFIETYFKEFPQIHEWMTKIKAQAHEQ  777
             RR AKAVNFGIVYGISD+GLSNNLGI+R ++K +I+TYF  +P I   M ++  +A ++
Sbjct  705  DRRNAKAVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDK  764

Query  778  GYVETIAKRRRYLPEIKSKNFNLRSFAERTAMNSPIQGSAADIIKIAMIKVADALKDNQL  837
            GYVET+ KRRR LP+I+S+NFN+RSFAERTA+NSPIQGSAADI+KIAMI++  AL+   +
Sbjct  765  GYVETLFKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGF  824

Query  838  QANILLQVHDELIFEAPEDEIETLRDIVTRVMDSAVALDVPMQVDSHYGNTWYDAK  893
            +A++LLQVHDE+++E P+DE+ +++ +V   M++AV L VP+ VD   G++WY+AK
Sbjct  825  RAKMLLQVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

239) polA in NC_014171


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  715 bits (2705),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 445/885 (51%), Positives = 662/885 (75%), Gaps = 19/885 (2%)

Query  3    KKVVLVDGNNIAYRAFFAL----PLLNNDKGIHTNAIYGFTMMLMRILEEEKPTHMLVAF  58
            +K++L+DG+++A+RAFFAL      ++N+ G+HTNAIYGF +ML +++   +PTH+LVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  59   DAGKTTFRHKTYSEYKGGRQKTPPELSEQFPFIREMLDAFNVPRYELENYEADDIMGTLA  118
            DAGKTTFR   Y++YK+GR KTP E+ EQF++IREML A+ ++ YELE+YEADDI+GTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  119  K--EASEQGASVKVISGDKDLLQLVSDNTLVCIPRKGITEVDEYTKEALFEKYSLSPKQI  176
            K  E +E    V ++SGDKDL+QL  +NT+V I++KG++E +E+T   L EK +L+P+Q+
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  177  IDMKGLMGDQSDNIPGVPGVGEKTAIKLLTQFGTVEEVYENLDQVSGkklkekleenkeQ  236
            ID+K+LMGD+SDNIPGV  +GEKT++KLL +FG++E +YE++D     K+KE+L ++++Q
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRDQ  244

Query  237  ALMSKDLATIITDAPITVHVDDMAYKGYEASDVIPMFESLGFTSLLNKLGVTPEETAPAE  296
            A++SK LATI T +PIT+ +DD+ Y+G + + +   ++ ++F  L + L+    + +   
Sbjct  245  AFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLA---SQMPQEP  301

Query  297  LDDITFDIVEEVTEEMLQQDSALIVEVQEDNYHKADIQGFGIQNENGCYFIQTDIAL-KS  355
            +  I+++ V +V+ +++  +  +  E   DNYH+  I GF+  + +  Y   TD++L  +
Sbjct  302  VAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIY-ASTDLSLLAT  360

Query  356  DAFKEWLADGEMRKHTFDAKRAIVALKWNGIDMQGIDFDLLIAAYLLDPADTDKDFRTVA  415
            D+FK+ +   +    T+D KR+ V L   GI++ +  +D  +A YLL   + D+++ T+A
Sbjct  361  DSFKQVF---QKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVE-DNELSTIA  416

Query  416  KMKETHAVKSDEEVYGKGAKRAVPELKVVAEHVARKVHVLYDVKQTFVEELKKNEQYELF  475
            ++    ++  D+ VYGKGAKRAVP+  V+ EH+ARKV VL D K   ++ L  +EQ +L+
Sbjct  417  RIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLY  476

Query  476  TELELPLARVLADMEVKGVKVDTERLRNMGEELAGRLKEMEQEIYKLAGTEFNINSPKQL  535
             ++ELPLA VLA ME+ G+KV+   L++M+E+    +  + QEIY +AG EFNINSPKQL
Sbjct  477  QNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQL  536

Query  536  GVILFENLNLP--VIKKTKTGYSTSADVLDKLMNHHEIIPNILHYRQLGKLNSTYIEGLL  593
            G ILFE+++LP  + KKTKTGYST+ DVL++L     I+++IL+YRQ+ KL+STY+ GL 
Sbjct  537  GSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQ  596

Query  594  KVVHEDSSKIHTRFNQVLTQTGRLSSTDPNLQNIPIRLEEGRKIRQAFVPSEEGWIMYAA  653
              +  D+ KIHTR+ Q LTQTGRLSS DPNLQNIPIRLE+GR IR+AF PS+E+ ++ ++
Sbjct  597  DYILADG-KIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSS  655

Query  654  DYSQIELRVLAHIANDKGLVEAFQHDMDIHTKTAMDVFGVEKD-EVTSNMRRQAKAVNFG  712
            DYSQIELRVLAHI+ D  L+ AF+++ DIHT TAM VFG++K  +VT+N RR+AKAVNFG
Sbjct  656  DYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFG  715

Query  713  IVYGISDYGLSQNLGITRKAAAEFIEKYLESFPGVQEYMEDIVKDAKQKGYVATLLNRRR  772
            IVYGISD+GLS+NLGITRK +  +I+ Y+E +PG++ YME++V++AK+KGYV TL++RRR
Sbjct  716  IVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRR  775

Query  773  YIPEITSRNFNLRSFAERTAMNTPIQGTaadiikkamiimadRLEEEGLQARLLLQVHDE  832
             +P+I SRNFN+RSFAERTA+N+PIQG+AADI+K AMI +   L+  G++A++LLQVHDE
Sbjct  776  ELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDE  835

Query  833  LIFEAPKEEIEKLEQLVPEVMEHAIELAVPLKVDYSYGPTWYDAK  877
            +++E P++E+  + +LV + ME A++LAVPL VD S G +WY+AK
Sbjct  836  IVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

240) polA in NC_017138


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  715 bits (2703),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 439/882 (50%), Positives = 657/882 (75%), Gaps = 15/882 (1%)

Query  3    QKLVLIDGNSIAYRAFFAL----PLLNNDKGIHTNAIYGFTTMLTRILEEEKPTHLLVAF  58
            +KL+LIDG+S+A+RAFFAL      ++N+ G+HTNAIYGF  ML +++   +PTH+LVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  59   DAGKTTFRHKTFTEYKGGRQKTPPELSEQFPFIRELLDAYGIKRYELPDYEADDIIGTLS  118
            DAGKTTFR   +++YK+GR KTP E+ EQF++IRE+L A GI  YEL +YEADDIIGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  119  KQAEQKGMA--VKVISGDKDLLQLVSEHVTVDITRKGITDVDSYTPAAIDEKYGITAAQI  176
            K AE+  ++  V ++SGDKDL+QL  E+  V+I++KG+++ + +TPA + EK G+T+ Q+
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  177  IDMKGLMGDSSDNIPGVPGVGEKTALKLLKEFETVENVLESIDQVSGKKLKEKLEDNRES  236
            ID+K+LMGD SDNIPGV  +GEKT+LKLL EF ++E + E ID     K+KE+L ++R+ 
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRDQ  244

Query  237  AIMSKKLATIYCEAPLEVSVEDAKYDGFESSKVISLFKELGFNSLLAKFGesaeeeadfe  296
            A++SK LATI   +P+ ++++D  Y+G + + +  ++ E++F  L   ++    +E+   
Sbjct  245  AFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEPVAV  304

Query  297  dlafeiaQEVHDDMLTSEAALIVEGYEENYHHNQLLGFGISNKNGHYFIDKDTALSSSKF  356
                E++ +V  D++++E  +  E   +NYH++ ++GF+ ++ +  Y     + L++  F
Sbjct  305  ISYQEVT-NVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLATDSF  363

Query  357  KAWLEDERVKKTVFNGKRTIVSLKWAGHEIKGIEHDVMIASYILNPAESNDDLATIAKLK  416
            K  ++      + ++ KR+ V L   G E+ +   D  +A+Y+L+  E +++L+TIA++ 
Sbjct  364  KQVFQKP---IATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVE-DNELSTIARIF  419

Query  417  GYHQVQSDEAVYGKGAKRSIAEADQLAEHVTRkaaavaylkellekelveNEQFELFEKL  476
                ++ D++VYGKGAKR++++ D L EH++RK   +   K  +   L  +EQ++L++++
Sbjct  420  TDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNI  479

Query  477  EMPLAIVLADMEYQGVKIDRAHLDEMGEDLREKLEKIEAKIYEYAGQEFNINSPKQLGVV  536
            E+PLA VLA ME +G+K++RA L++M+E+ +  +E +   IY+ AGQEFNINSPKQLG +
Sbjct  480  ELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSI  539

Query  537  LFEKMQLP--VIKKTKTGYSTSADVLEQLASAHDIIPEILQYRQLGKLQSTYIEGLKKVI  594
            LFEKMQLP  + KKTKTGYST+ DVLE+LA+   I++ IL+YRQ+ KLQSTY+ GL+  I
Sbjct  540  LFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYI  599

Query  595  HESDGKVHTRFNQTLTQTGRLSSVDPNLQNIPIRLEEGKKIRGAFVPSQPDWLIFAADYS  654
              +DGK+HTR+ Q LTQTGRLSSVDPNLQNIPIRLE+G+ IR AF PS+ D +++++DYS
Sbjct  600  L-ADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYS  658

Query  655  QIELRVLAHIADDEKLIDAFKHDLDIHTKTAMDVFHVERE-EVTSNMRRQAKAVNFGIVY  713
            QIELRVLAHI++DE LI AF+++ DIHT TAM VF +++  +VT+N RR+AKAVNFGIVY
Sbjct  659  QIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVY  718

Query  714  GISDYGLSQSLGITRKAAATFIERYLKSFPGVQEYMDTIVRDAKEKGYVTTLLHRRRYLP  773
            GISD+GLS++LGITRK + ++I+ Y+  +PG++ YM+ +VR+AK+KGYV TL+ RRR LP
Sbjct  719  GISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELP  778

Query  774  EITSRNFNLRSFAERTAMNTPIQGTAADIIKKAMIEMDKRLKDENLQAKLLLQVHDELIF  833
            +I SRNFN+RSFAERTA+N+PIQG+AADI+K AMI++DK L+   ++AK+LLQVHDE+++
Sbjct  779  DINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVL  838

Query  834  EAPEEEIKILEKIVPEVMEHALELEVPLKVDYSYGKTWYEAK  875
            E P++E+  + K+V + ME A++L VPL VD S G++WYEAK
Sbjct  839  EVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

241) polA2 in NC_018877


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  714 bits (2701),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 445/885 (51%), Positives = 662/885 (75%), Gaps = 19/885 (2%)

Query  3    KKVVLVDGNNIAYRAFFAL----PLLNNDKGIHTNAIYGFTMMLMRILEEEKPTHMLVAF  58
            +K++L+DG+++A+RAFFAL      ++N+ G+HTNAIYGF +ML +++   +PTH+LVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  59   DAGKTTFRHKTYSEYKGGRQKTPPELSEQFPFIREMLDAFNVPRYELENYEADDIMGTLA  118
            DAGKTTFR   Y++YK+GR KTP E+ EQF++IREML A+ ++ YELE+YEADDI+GTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  119  K--EASEQGASVKVISGDKDLLQLVSDNTLVCIPRKGITEVDEYTKEALFEKYSLSPKQI  176
            K  E +E    V ++SGDKDL+QL  +NT+V I++KG++E +E+T   L EK +L+P+Q+
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  177  IDMKGLMGDQSDNIPGVPGVGEKTAIKLLTQFGTVEEVYENLDQVSGkklkekleenkeQ  236
            ID+K+LMGD+SDNIPGV  +GEKT++KLL +FG++E +YE++D     K+KE+L ++++Q
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRDQ  244

Query  237  ALMSKDLATIITDAPITVHVDDMAYKGYEASDVIPMFESLGFTSLLNKLGVTPEETAPAE  296
            A++SK LATI T +PIT+ +DD+ Y+G + + +   ++ ++F  L + L+    + +   
Sbjct  245  AFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLA---SQMPQEP  301

Query  297  LDDITFDIVEEVTEEMLQQNSALIVEVQEDNYHKADIQGFGIQNENGCYFIQKDIAL-AS  355
            +  I+++ V +V+ +++  +  +  E   DNYH+  I GF+  + +  Y    D++L A+
Sbjct  302  VAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIY-ASTDLSLLAT  360

Query  356  DAFKAWLANGEMRKHTFDAKRAIVALKWNGIDMQGIDFDLLIAAYLLDPADTDKDFRTVA  415
            D+FK  +   +    T+D KR+ V L   GI++ +  +D  +A YLL   + D+++ T+A
Sbjct  361  DSFKQVF---QKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVE-DNELSTIA  416

Query  416  KMKETHAVKSDEEVYGKGAKRAVPELEVVAEHVARKVHVLYDVKQTFVEELKKNEQYELF  475
            ++    ++  D+ VYGKGAKRAVP+ +V+ EH+ARKV VL D K   ++ L  +EQ +L+
Sbjct  417  RIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLY  476

Query  476  TELELPLARVLADMEVKGVKVDTERLRNMGEELVGRLKEMEQEIYKLAGTEFNINSPKQL  535
             ++ELPLA VLA ME+ G+KV+   L++M+E+    +  + QEIY +AG EFNINSPKQL
Sbjct  477  QNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQL  536

Query  536  GVILFENLNLP--VIKKTKTGYSTSADVLDKLMDRHEIIPNILHYRQLGKLNSTYIEGLL  593
            G ILFE+++LP  + KKTKTGYST+ DVL++L     I+++IL+YRQ+ KL+STY+ GL 
Sbjct  537  GSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQ  596

Query  594  KVVHEDSSKIHTRFNQVLTQTGRLSSTDPNLQNIPIRLEEGRKIRQAFVPSEEGWIMYAA  653
              +  D+ KIHTR+ Q LTQTGRLSS DPNLQNIPIRLE+GR IR+AF PS+E+ ++ ++
Sbjct  597  DYILADG-KIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSS  655

Query  654  DYSQIELRVLAHIANDKGLVEAFQHDMDIHTKTAMDVFGVEKD-EVTSNMRRQAKAVNFG  712
            DYSQIELRVLAHI+ D  L+ AF+++ DIHT TAM VFG++K  +VT+N RR+AKAVNFG
Sbjct  656  DYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFG  715

Query  713  IVYGISDYGLSQNLGITRKAAAEFIEKYLESFPGVQEYMEDIVKDAKQKGYVATLLNRRR  772
            IVYGISD+GLS+NLGITRK +  +I+ Y+E +PG++ YME++V++AK+KGYV TL++RRR
Sbjct  716  IVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRR  775

Query  773  YIPEITSRNFNLRSFAERTAMNTPIQGTaadiikkamiimadRLEEEGLQARLLLQVHDE  832
             +P+I SRNFN+RSFAERTA+N+PIQG+AADI+K AMI +   L+  G++A++LLQVHDE
Sbjct  776  ELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDE  835

Query  833  LIFEAPKEEIEKLEQLVPEVMEHAIELAVPLKVDYSYGPTWYDAK  877
            +++E P++E+  + +LV + ME A++LAVPL VD S G +WY+AK
Sbjct  836  IVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

242) polA in NC_017208


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  714 bits (2701),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 445/885 (51%), Positives = 662/885 (75%), Gaps = 19/885 (2%)

Query  3    KKVVLVDGNNIAYRAFFAL----PLLNNDKGIHTNAIYGFTMMLMRILEEEKPTHMLVAF  58
            +K++L+DG+++A+RAFFAL      ++N+ G+HTNAIYGF +ML +++   +PTH+LVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  59   DAGKTTFRHKTYSEYKGGRQKTPPELSEQFPFIREMLDAFNVPRYELENYEADDIMGTLA  118
            DAGKTTFR   Y++YK+GR KTP E+ EQF++IREML A+ ++ YELE+YEADDI+GTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  119  K--EASEQGASVKVISGDKDLLQLVSDNTLVCIPRKGITEVDEYTKEALFEKYSLSPKQI  176
            K  E +E    V ++SGDKDL+QL  +NT+V I++KG++E +E+T   L EK +L+P+Q+
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  177  IDMKGLMGDQSDNIPGVPGVGEKTAIKLLTQFGTVEEVYENLDQVSGkklkekleenkeQ  236
            ID+K+LMGD+SDNIPGV  +GEKT++KLL +FG++E +YE++D     K+KE+L ++++Q
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRDQ  244

Query  237  ALMSKDLATIITDAPITVHVDDMAYKGYEASDVIPMFESLGFTSLLNKLGVTPEETAPAE  296
            A++SK LATI T +PIT+ +DD+ Y+G + + +   ++ ++F  L + L+    + +   
Sbjct  245  AFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLA---SQMPQEP  301

Query  297  LDDITFDIVEEVTEEMLQQNSALIVEVQEDNYHKADIQGFGIQNENGCYFIQKDIAL-AS  355
            +  I+++ V +V+ +++  +  +  E   DNYH+  I GF+  + +  Y    D++L A+
Sbjct  302  VAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIY-ASTDLSLLAT  360

Query  356  DAFKAWLANGEMRKHTFDAKRAIVALKWNGIDMQGIDFDLLIAAYLLDPADTDKDFRTVA  415
            D+FK  +   +    T+D KR+ V L   GI++ +  +D  +A YLL   + D+++ T+A
Sbjct  361  DSFKQVF---QKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVE-DNELSTIA  416

Query  416  KMKETHAVKSDEEVYGKGAKRAVPELEVVAEHVARKVHVLYDVKQTFVEELKKNEQYELF  475
            ++    ++  D+ VYGKGAKRAVP+ +V+ EH+ARKV VL D K   ++ L  +EQ +L+
Sbjct  417  RIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLY  476

Query  476  TELELPLARVLADMEVKGVKVDTERLRNMGEELVGRLKEMEQEIYKLAGTEFNINSPKQL  535
             ++ELPLA VLA ME+ G+KV+   L++M+E+    +  + QEIY +AG EFNINSPKQL
Sbjct  477  QNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQL  536

Query  536  GVILFENLNLP--VIKKTKTGYSTSADVLDKLMDRHEIIPNILHYRQLGKLNSTYIEGLL  593
            G ILFE+++LP  + KKTKTGYST+ DVL++L     I+++IL+YRQ+ KL+STY+ GL 
Sbjct  537  GSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQ  596

Query  594  KVVHEDSSKIHTRFNQVLTQTGRLSSTDPNLQNIPIRLEEGRKIRQAFVPSEEGWIMYAA  653
              +  D+ KIHTR+ Q LTQTGRLSS DPNLQNIPIRLE+GR IR+AF PS+E+ ++ ++
Sbjct  597  DYILADG-KIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSS  655

Query  654  DYSQIELRVLAHIANDKGLVEAFQHDMDIHTKTAMDVFGVEKD-EVTSNMRRQAKAVNFG  712
            DYSQIELRVLAHI+ D  L+ AF+++ DIHT TAM VFG++K  +VT+N RR+AKAVNFG
Sbjct  656  DYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFG  715

Query  713  IVYGISDYGLSQNLGITRKAAAEFIEKYLESFPGVQEYMEDIVKDAKQKGYVATLLNRRR  772
            IVYGISD+GLS+NLGITRK +  +I+ Y+E +PG++ YME++V++AK+KGYV TL++RRR
Sbjct  716  IVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRR  775

Query  773  YIPEITSRNFNLRSFAERTAMNTPIQGTaadiikkamiimadRLEEEGLQARLLLQVHDE  832
             +P+I SRNFN+RSFAERTA+N+PIQG+AADI+K AMI +   L+  G++A++LLQVHDE
Sbjct  776  ELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDE  835

Query  833  LIFEAPKEEIEKLEQLVPEVMEHAIELAVPLKVDYSYGPTWYDAK  877
            +++E P++E+  + +LV + ME A++LAVPL VD S G +WY+AK
Sbjct  836  IVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

243) H175_ch4680 in NC_020376


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  714 bits (2701),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 445/885 (51%), Positives = 662/885 (75%), Gaps = 19/885 (2%)

Query  3    KKVVLVDGNNIAYRAFFAL----PLLNNDKGIHTNAIYGFTMMLMRILEEEKPTHMLVAF  58
            +K++L+DG+++A+RAFFAL      ++N+ G+HTNAIYGF +ML +++   +PTH+LVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  59   DAGKTTFRHKTYSEYKGGRQKTPPELSEQFPFIREMLDAFNVPRYELENYEADDIMGTLA  118
            DAGKTTFR   Y++YK+GR KTP E+ EQF++IREML A+ ++ YELE+YEADDI+GTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  119  K--EASEQGASVKVISGDKDLLQLVSDNTLVCIPRKGITEVDEYTKEALFEKYSLSPKQI  176
            K  E +E    V ++SGDKDL+QL  +NT+V I++KG++E +E+T   L EK +L+P+Q+
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  177  IDMKGLMGDQSDNIPGVPGVGEKTAIKLLTQFGTVEEVYENLDQVSGkklkekleenkeQ  236
            ID+K+LMGD+SDNIPGV  +GEKT++KLL +FG++E +YE++D     K+KE+L ++++Q
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRDQ  244

Query  237  ALMSKDLATIITDAPITVHVDDMAYKGYEASDVIPMFESLGFTSLLNKLGVTPEETAPAE  296
            A++SK LATI T +PIT+ +DD+ Y+G + + +   ++ ++F  L + L+    + +   
Sbjct  245  AFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLA---SQMPQEP  301

Query  297  LDDITFDIVEEVTEEMLQQNSALIVEVQEDNYHKADIQGFGIQNENGCYFIQKDIAL-AS  355
            +  I+++ V +V+ +++  +  +  E   DNYH+  I GF+  + +  Y    D++L A+
Sbjct  302  VAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIY-ASTDLSLLAT  360

Query  356  DAFKAWLANGEMRKHTFDAKRAIVALKWNGIDMQGIDFDLLIAAYLLDPADTDKDFRTVA  415
            D+FK  +   +    T+D KR+ V L   GI++ +  +D  +A YLL   + D+++ T+A
Sbjct  361  DSFKQVF---QKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVE-DNELSTIA  416

Query  416  KMKETHAVKSDEEVYGKGAKRAVPELEVVAEHVARKVHVLYDVKQTFVEELKKNEQYELF  475
            ++    ++  D+ VYGKGAKRAVP+ +V+ EH+ARKV VL D K   ++ L  +EQ +L+
Sbjct  417  RIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLY  476

Query  476  TELELPLARVLADMEVKGVKVDTERLRNMGEELVGRLKEMEQEIYKLAGTEFNINSPKQL  535
             ++ELPLA VLA ME+ G+KV+   L++M+E+    +  + QEIY +AG EFNINSPKQL
Sbjct  477  QNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQL  536

Query  536  GVILFENLNLP--VIKKTKTGYSTSADVLDKLMDRHEIIPNILHYRQLGKLNSTYIEGLL  593
            G ILFE+++LP  + KKTKTGYST+ DVL++L     I+++IL+YRQ+ KL+STY+ GL 
Sbjct  537  GSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQ  596

Query  594  KVVHEDSSKIHTRFNQVLTQTGRLSSTDPNLQNIPIRLEEGRKIRQAFVPSEEGWIMYAA  653
              +  D+ KIHTR+ Q LTQTGRLSS DPNLQNIPIRLE+GR IR+AF PS+E+ ++ ++
Sbjct  597  DYILADG-KIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSS  655

Query  654  DYSQIELRVLAHIANDKGLVEAFQHDMDIHTKTAMDVFGVEKD-EVTSNMRRQAKAVNFG  712
            DYSQIELRVLAHI+ D  L+ AF+++ DIHT TAM VFG++K  +VT+N RR+AKAVNFG
Sbjct  656  DYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFG  715

Query  713  IVYGISDYGLSQNLGITRKAAAEFIEKYLESFPGVQEYMEDIVKDAKQKGYVATLLNRRR  772
            IVYGISD+GLS+NLGITRK +  +I+ Y+E +PG++ YME++V++AK+KGYV TL++RRR
Sbjct  716  IVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRR  775

Query  773  YIPEITSRNFNLRSFAERTAMNTPIQGTaadiikkamiimadRLEEEGLQARLLLQVHDE  832
             +P+I SRNFN+RSFAERTA+N+PIQG+AADI+K AMI +   L+  G++A++LLQVHDE
Sbjct  776  ELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDE  835

Query  833  LIFEAPKEEIEKLEQLVPEVMEHAIELAVPLKVDYSYGPTWYDAK  877
            +++E P++E+  + +LV + ME A++LAVPL VD S G +WY+AK
Sbjct  836  IVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

244) polA in NC_003909


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  713 bits (2697),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 445/885 (51%), Positives = 664/885 (76%), Gaps = 19/885 (2%)

Query  3    KKVVLVDGNNIAYRAFFAL----PLLNNDKGIHTNAIYGFTMMLMRILEEEKPTHMLVAF  58
            +K++L+DG+++A+RAFFAL      ++N+ G+HTNAIYGF +ML +++   +PTH+LVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  59   DAGKTTFRHKTYSEYKGGRQKTPPELSEQFPFIREMLDAFNVPRYELENYEADDIMGTLA  118
            DAGKTTFR   Y++YK+GR KTP E+ EQF++IREML A+ ++ YELE+YEADDI+GTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  119  K--EASEQGASVKVISGDKDLLQLVSDNTLVCIPRKGITEVDEYTKEALFEKYSLSPKQI  176
            K  E +E    V ++SGDKDL+QL  +NT+V I++KG++E +E+T   L EK +L+P+Q+
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  177  IDMKGLMGDQSDNIPGVPGVGEKTAIKLLTQFGTVEEVYENIDQVSGkklkekleankeq  236
            ID+K+LMGD+SDNIPGV  +GEKT++KLL +FG++E +YE+ID     K+KE+L  +++Q
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRDQ  244

Query  237  alMSKDLATIITDAPITVHVDDMEYKGYEASDVIPMFENLGFTSLLNKLGVTPEETAPAE  296
            A++SK LATI T +PIT+ +DD+ Y+G + + +   +++++F  L + L+    + +   
Sbjct  245  AFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLA---SQMPQEP  301

Query  297  LDDITFDIVEEVTEEMLQQDSALIVEVQEDNYHKADIQGFGIQNENGCYFIQTDIAL-KS  355
            +  I+++ V +V+ +++  +  +  E   DNYH+  I GF+  + +  Y   TD++L  +
Sbjct  302  VAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIY-ASTDLSLLAT  360

Query  356  DAFKEWLADGEMRKYTFDAKRAIVALKWNGIDMQGIDFDLLIAAYLLDPADTDKDFRTVA  415
            D+FK+ + +  +  Y F  KR+ V L   GI++ +  +D  +A YLL   + D+++ T+A
Sbjct  361  DSFKQ-VFQKPIATYDF--KRSKVLLSHLGIELVAPSYDARLANYLLSTVE-DNELSTIA  416

Query  416  KMKETHAVKSDEEVYGKGAKRAVPELEIVAEHVARKVHVLYDVKQTFVEELEKNEQYELF  475
            ++    ++  D+ VYGKGAKRAVP+ +++ EH+ARKV VL D K   ++ L  +EQ +L+
Sbjct  417  RIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLY  476

Query  476  TELELPLARVLADMEVKGVKVDTERLRNMGEELAGRLKEMEQEIYKLAGREFNINSPKQL  535
             ++ELPLA VLA ME+ G+KV+   L++M+E+    +  + QEIY +AG+EFNINSPKQL
Sbjct  477  QNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQL  536

Query  536  GVILFENLNLP--VIKKTKTGYSTSADVLDKLMDHHEIIPNILHYRQLGKLNSTYIEGLL  593
            G ILFE+++LP  + KKTKTGYST+ DVL++L     I+++IL+YRQ+ KL+STY+ GL 
Sbjct  537  GSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQ  596

Query  594  KVVHEDSSKIHTRFNQVLTQTGRLSSTDPNLQNIPIRLEEGRKIRQAFVPSEEGWIMYAA  653
              +  D+ KIHTR+ Q LTQTGRLSS DPNLQNIPIRLE+GR IR+AF PS+E+ ++ ++
Sbjct  597  DYILADG-KIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSS  655

Query  654  DYSQIELRVLAHIANDKGLVEAFQHDMDIHTKTAMDVFGVEKD-EVTSNMRRQAKAVNFG  712
            DYSQIELRVLAHI+ D  L+ AF+++ DIHT TAM VFG++K  +VT+N RR+AKAVNFG
Sbjct  656  DYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFG  715

Query  713  IVYGISDYGLSQNLGITRKAAAEFIEKYLESFPGVQEYMDDIVKDAKQKGYVATLLNRRR  772
            IVYGISD+GLS+NLGITRK +  +I+ Y+E +PG++ YM+++V++AK+KGYV TL++RRR
Sbjct  716  IVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRR  775

Query  773  YIPEITSRNFNLRSFAERTAMNTPIQGTaadiikkamiimadRLEEEGLQARLLLQVHDE  832
             +P+I SRNFN+RSFAERTA+N+PIQG+AADI+K AMI +   L+  G++A++LLQVHDE
Sbjct  776  ELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDE  835

Query  833  LIFEAPKEEIEKLEKLVPEVMEHAIELAVPLKVDYSYGPTWYDAK  877
            +++E P++E+  + KLV + ME A++LAVPL VD S G +WY+AK
Sbjct  836  IVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

245) polA in NC_017568


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  712 bits (2692),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 432/891 (49%), Positives = 650/891 (73%), Gaps = 32/891 (3%)

Query  2    DKLILIDGNSLSFRAFYAL----PLLKNKAGIHTNAVYGFARLLEKIIKEEQPTHFLVAF  57
            +KL+LIDG+S++FRAF+AL      +KN +G+HTNA+YGF  +L+ ++K  +PTH LVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  58   DAGKTTFRHETYQDYKGGRQKTPPELSEQFPYIRQLIDAYQIQRYELENYEADDIIGTLS  117
            DAGKTTFR E Y DYK+GR KTP E+ EQF+YIR+++ A  I  YELE+YEADDIIGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  118  READQAGM--QTIIITGDRDLTQLATDQVTIYYTKKGVTDVDHYTPQFIAEKYNGLKPSQ  175
            + A+++ +  +  I++GD+DL QL+ ++  +  +KKGV++ +++TP ++ EK  GL P+Q
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEK-MGLTPNQ  183

Query  176  IIDLKGLMGDSSDNIPGVAGVGEKTAMKLLNQFGTVEGVYDHIEEVSGKKLKEKLENSRD  235
            +IDLK+LMGD SDNIPGV+ +GEKT++KLL++FG++EG+Y+HI+     K+KE+L N RD
Sbjct  184  FIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRD  243

Query  236  DALMSKTLATINCDSPITVSLEDTRLPQKMDESAKIELFKSLEFRQLLDGMDVE-ADNAT  294
            +A++SKTLATIN  SPIT++L+D       D ++  +++  ++F QL  G+  + ++++ 
Sbjct  244  QAFLSKTLATINTASPITIGLDDIVYNGP-DVASLSQFYDEMDFVQLKKGLASQMPQEPV  302

Query  295  ASRDFVPTTNMSKVDFTQLSEAAIHVEVAGPNYLKDELLKFG------LYDGEQYVVIPF  348
            A   +   TN+S   F+  +E  +  E    NY ++ ++ F+      +Y + +  +++ 
Sbjct  303  AVISYQEVTNVSADLFS--AEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLAT  360

Query  349  DKVNE-YPELVAWLEDETTQKWVHDAKKTYIAMKRSDIAIENVVFDTMLASYIIDPSRTI  407
            D  ++ +   +A            D K++ + + + +I +    +D+ LA+Y++      
Sbjct  361  DSFKQVFQKPIA----------TYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-  409

Query  408  EDVQSVMTHFDQTFVQDDVSVYGKGKSFHIPEDDILDKHIASILDAIHVVQPQMMTILEA  467
            +++ ++   F +  +++D +VYGKG    +P+ D+L  H+A  +  +   ++QM+  L A
Sbjct  410  NELSTIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTA  469

Query  468  HEQTSLLSEIELPLALILSEMEYIGIHTDIDTLKEMETVIQTELDQLIEQIHEQAGEKFN  527
            HEQ  L  +IELPLA +L+ ME  GI  +  TL++M    +  ++ L ++I + AG+ FN
Sbjct  470  HEQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFN  529

Query  528  INSPKQLGVILFEKLELP--VIKKTKTGYSTAVDVLEKLQNAHPIIDNILTYRTLSKLQS  585
            INSPKQLG ILFEK++LP  + KKTKTGYSTAVDVLE+L    PI+ +IL YR ++KLQS
Sbjct  530  INSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQS  589

Query  586  TYVEGLQKVIWDDGRIHTRFNQTLAQTGRLSSVDPNLQNIPIRLEEGRKIRKAFKSTHED  645
            TYV GLQ  I  DG+IHTR+ Q L+QTGRLSSVDPNLQNIPIRLE+GR IRKAF ++HED
Sbjct  590  TYVIGLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHED  649

Query  646  YVILAADYSQIELRVLAHITGDPTLQQAFNDNEDVHTTTAMKVFNVA-AGEVTSLMRRQA  704
             V+L++DYSQIELRVLAHI+GD  L  AFN+  D+HT+TAM+VF +  A++VT+  RR+A
Sbjct  650  AVLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNA  709

Query  705  KAVNFGIVYGISDYGLSQSLGITRKEAQRFIDDYLNHFPGVKDYMDNIVQDAKQQGYVET  764
            KAVNFGIVYGISD+GLS++LGITRK+++ +ID Y++++PG+K YM+N+V++AK++GYVET
Sbjct  710  KAVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVET  769

Query  765  LLKRRRYIPDITSRNFNLRGFAERTAMNSPIQGSAADIIKLAMVQFHREVQKTSFKAQLL  824
            L+KRRR +PDI SRNFN+R+FAERTA+NSPIQGSAADI+K+AM+++++ +Q  +F+A++L
Sbjct  770  LFKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKML  829

Query  825  LQVHDELIFEVPKDEVDEFGKFVEEIMAHALQLDVPLSVESDYGKTWYDAK  875
            LQVHDE+++EVP+DE+  + K+V + M  A++L VPL V+   G++WY+AK
Sbjct  830  LQVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

246) polA in NC_002570


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  711 bits (2691),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 430/884 (49%), Positives = 645/884 (73%), Gaps = 17/884 (1%)

Query  2    KKLVLIDGNSIAYRAFFAL----PLLNNDKGVYTNAVYGFTMMLLKVLEDEKPTHMVVAF  57
            +KL+LIDG+S+A+RAFFAL      ++N+ G+ TNA+YGF +ML  ++   +PTH++VAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  58   DAGKTTFRHDTYDAYKSGRQKTPPELSEQFPLIRELLDAFNIARVEVENFEADDLIGTLA  117
            DAGKTTFR + Y  YK+GR KTP E+ EQF+ IRE+L A+ IA  E+E++EADD+IGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  118  KQA--SQENFEVKIFTGDKDLLQIVSDHVTVALTRKGITQIDVYDEKGIEERYGITPEQI  175
            K A  ++  F+V I +GDKDL+Q+  ++  V +++KG+++++ +    + E+ G+TP+Q+
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  176  IDMKGLMGDSSDNIPGVPGIGEKTALKLLKEYGSVEKVLESIDEISGKKMKERLEEHRDQ  235
            ID+K+LMGD SDNIPGV  IGEKT+LKLL E+GS+E + E ID +   KMKE L ++RDQ
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRDQ  244

Query  236  ALMSKKLATIYLEAPVTLDADSFTFGEYDKKEVVKLFKELDFNSLLDKVDADGEGIEKEE  295
            A++SK LATI   +P+T++ D + +   D   + +++ E+DF  L   + ++   + +E 
Sbjct  245  AFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQ---MPQEP  301

Query  296  LQSLNYETLREVKEAHLADKAALVVEVLDENYHQGDILGLAIAHNNGCYYIPTDEALRSE  355
            +  ++Y+ + +V    ++    +  E L +NYH+  I+G+A +H +  Y       L ++
Sbjct  302  VAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLATD  361

Query  356  ALIQWLKDERKEKWLFDAKRAVVALGWKNIELAGSTFDLQMASYLLDPSTSFHEVSDVTK  415
            ++ Q +   +K    +D KR+ V L+   IEL ++++D ++A+YLL      +E+S +++
Sbjct  362  SFKQVF---QKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NELSTIAR  417

Query  416  HHRKGHVHEDEAVYGKGAKRRIPDEKELGEHLARKADAIFQLKEHVEEKLKENEQLGLFN  475
                  ++ED++VYGKGAKR +PD   L EHLARK   +++ K ++ +KL  +EQL+L++
Sbjct  418  IFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQ  477

Query  476  ELEMPLSVILGRMETTGVKVDVEQLEQMGEDLNARLEELEQTIHELAGVSFNINSPKQLG  535
            ++E+PL+ +L++ME  G+KV+   L++M+E+ +  +E L Q I ++AG  FNINSPKQLG
Sbjct  478  NIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLG  537

Query  536  EILFEKLQLP--VIKKTKTGYSTSADVLEKLAGQHEIIDHILHYRQLGKLNSTYIDGLLK  593
             ILFEK+QLP  + KKTKTGYST+ DVLE+LA    I+  IL+YRQ+ KL+STY+ GL  
Sbjct  538  SILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQD  597

Query  594  VVHKGTGKVHTRFNQALTQTGRLSSTDPNLQNIPIRLEEGRKIRKAFVPSEKDWFILAAD  653
             +  + GK+HTR+ Q LTQTGRLSS DPNLQNIPIRLE+GR IRKAF PS+ D  +L++D
Sbjct  598  YIL-ADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSD  656

Query  654  YSQIELRVLAHFAEDEKLMEAFREDMDVHTKTAMDVFHVSQE-EVTSNMRRSAKAVNFGI  712
            YSQIELRVLAH++ DE L+ AF E+ D+HT TAM VF + +  +VT+N RR+AKAVNFGI
Sbjct  657  YSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGI  716

Query  713  VYGISDYGLSQNLGITRKEAATFIERYFASYPKVKEYLDHVIDEAREKGYVTTLLKRRRY  772
            VYGISD+GLS+NLGITRK++ ++I+ YF  YP +K Y+++V+ EA++KGYV TL+KRRR 
Sbjct  717  VYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRE  776

Query  773  LPDLTSRNFNQRSFAERTAMNTPIQGTAADIIKQAMVQMASRMDEEDLQSRLLLQVHDEL  832
            LPD+ SRNFN RSFAERTA+N+PIQG+AADI+K AM+++   ++  ++++++LLQVHDE+
Sbjct  777  LPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEI  836

Query  833  IFEVPKEEVAQMKELVTSVMEQAVELRVPLKVDVACGDTWYDAK  876
            ++EVP++E++ +K LV   ME AV+L VPL VD + G++WY+AK
Sbjct  837  VLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

247) BCK_12285 in NC_018491


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  710 bits (2686),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 444/885 (51%), Positives = 662/885 (75%), Gaps = 19/885 (2%)

Query  3    KKVVLVDGNNIAYRAFFAL----PLLNNDKGIHTNAIYGFTMMLMRILEEEKPTHMLVAF  58
            +K++L+DG+++A+RAFFAL      ++N+ G+HTNAIYGF +ML +++   +PTH+LVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  59   DAGKTTFRHKTYSEYKGGRQKTPPELSEQFPFIREMLDAFNVPRYELENYEADDIMGTLA  118
            DAGKTTFR   Y++YK+GR KTP E+ EQF++IREML A+ ++ YELE+YEADDI+GTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  119  K--EASEQGASVKVISGDKDLLQLVSDNTLVCIPRKGITEVDEYTKEALFEKYSLSPKQI  176
            K  E +E    V ++SGDKDL+QL  +NT+V I++KG++E +E+T   L EK +L+P+Q+
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  177  IDMKGLMGDQSDNIPGVPGVGEKTAIKLLTQFGTVEEVYENIDQVSGkklkekleankeq  236
            ID+K+LMGD+SDNIPGV  +GEKT++KLL +FG++E +YE+ID     K+KE+L  +++Q
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRDQ  244

Query  237  alMSKDLATIITDAPITVHVDDMEYKGYEASDVIPMFENLGFTSLLNKLGVTPEETAPAE  296
            A++SK LATI T +PIT+ +DD+ Y+G + + +   +++++F  L + L+    + +   
Sbjct  245  AFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLA---SQMPQEP  301

Query  297  LDDITFDIVEEVTEEMLQQDSALIVEVQEDNYHKADIQGFGIQNENGCYFIQTDIAL-KS  355
            +  I+++ V +V+ +++  +  +  E   DNYH+  I GF+  + +  Y   TD++L  +
Sbjct  302  VAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIY-ASTDLSLLAT  360

Query  356  DAFKEWLADGEMRKYTFDAKRAIVALKWNGIDVQGIDFDLLIAAYLLDPADTDKDFRTVA  415
            D+FK+ + +  +  Y F  KR+ V L   GI++ +  +D  +A YLL   + D+++ T+A
Sbjct  361  DSFKQ-VFQKPIATYDF--KRSKVLLSHLGIELVAPSYDARLANYLLSTVE-DNELSTIA  416

Query  416  KMKETHAVKSDEEVYGKGAKRAVPELEIVAEHVARKVHVLYDVKQTFVEELEKNEQYELF  475
            ++    ++  D+ VYGKGAKRAVP+ +++ EH+ARKV VL D K   ++ L  +EQ +L+
Sbjct  417  RIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLY  476

Query  476  TELELPLARVLADMEVKGVKVDTERLRNMGEELAGRLKEMEQEIYKLAGTEFNINSPKQL  535
             ++ELPLA VLA ME+ G+KV+   L++M+E+    +  + QEIY +AG EFNINSPKQL
Sbjct  477  QNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQL  536

Query  536  GVILFENLNLP--VIKKTKTGYSTSADVLDKLMDHHEIIPNILHYRQLGKLNSTYIEGLL  593
            G ILFE+++LP  + KKTKTGYST+ DVL++L     I+++IL+YRQ+ KL+STY+ GL 
Sbjct  537  GSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQ  596

Query  594  KVVHEDSSKIHTRFNQVLTQTGRLSSTDPNLQNIPIRLEEGRKIRQAFVPSEEGWIMYAA  653
              +  D+ KIHTR+ Q LTQTGRLSS DPNLQNIPIRLE+GR IR+AF PS+E+ ++ ++
Sbjct  597  DYILADG-KIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSS  655

Query  654  DYSQIELRVLAHIANDKGLVEAFQHDMDIHTKTAMDVFGVEKD-EVTSNMRRQAKAVNFG  712
            DYSQIELRVLAHI+ D  L+ AF+++ DIHT TAM VFG++K  +VT+N RR+AKAVNFG
Sbjct  656  DYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFG  715

Query  713  IVYGISDYGLSQNLGITRKAAAEFIEKYLKSFPGVQEYMDDIVKDAKQKGYVATLLNRRR  772
            IVYGISD+GLS+NLGITRK +  +I+ Y+  +PG++ YM+++V++AK+KGYV TL++RRR
Sbjct  716  IVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRR  775

Query  773  YIPEITSRNFNLRSFAERTAMNTPIQGTaadiikkamiimadRLEEEGLQARLLLQVHDE  832
             +P+I SRNFN+RSFAERTA+N+PIQG+AADI+K AMI +   L+  G++A++LLQVHDE
Sbjct  776  ELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDE  835

Query  833  LIFEAPKEEIEKLEKLVPEVMEHAIELAVPLKVDYSYGPTWYDAK  877
            +++E P++E+  + KLV + ME A++LAVPL VD S G +WY+AK
Sbjct  836  IVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

248) BcerKBAB4_4417 in NC_010184


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  710 bits (2687),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 446/885 (51%), Positives = 665/885 (76%), Gaps = 19/885 (2%)

Query  3    KKVVLVDGNNIAYRAFFAL----PLLNNDKGIHTNAIYGFTMMLMRILEEEKPTHMLVAF  58
            +K++L+DG+++A+RAFFAL      ++N+ G+HTNAIYGF +ML +++   +PTH+LVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  59   DAGKTTFRHKTYSDYKGGRQKTPPELSEQFPFIREVLDAFNVPRYELENYEADDIMGTLA  118
            DAGKTTFR   Y+DYK+GR KTP E+ EQF++IRE+L A+ ++ YELE+YEADDI+GTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  119  K--EASEQGFHVKVISGDKDLLQLVSDNTLVCIPRKGITEVDEYTKEALFEKYSLSPKQI  176
            K  E +E  F+V ++SGDKDL+QL  +NT+V I++KG++E +E+T   L EK +L+P+Q+
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  177  IDMKGLMGDQSDNIPGVPGVGEKTAIKLLTQFETVEAVYENLDQVSGkklkekleankeq  236
            ID+K+LMGD+SDNIPGV  +GEKT++KLL +F ++E++YE++D     K+KE+L  +++Q
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRDQ  244

Query  237  alMSKELATIITDAPITVHVDDMEYKGYEPSDLIPMFENLGFTSLLNKLGVTPEETAPAE  296
            A++SK LATI T +PIT+ +DD+ Y+G + + L   +++++F  L + L+    + +   
Sbjct  245  AFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLA---SQMPQEP  301

Query  297  LDDITFDIVEEVTEEMLQQDSALIVEVQEDNYHKADIQGFGIQNENGCYFIPADVAL-KS  355
            +  I+++ V +V+ +++  +  +  E   DNYH+  I GF+  + +  Y  ++D++L  +
Sbjct  302  VAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIY-ASTDLSLLAT  360

Query  356  DAFKEWLANGEMRKHTFDAKRAIVALKWKGVDIQGIDFDLLIAAYLLDPADTDKDFRTVA  415
            D+FK+ +   +    T+D KR+ V L   G+++ +  +D  +A YLL   + D+++ T+A
Sbjct  361  DSFKQVF---QKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVE-DNELSTIA  416

Query  416  KMKETHAVKSDEEVYGKGAKRAVPGLEVVAEHVARKVHVLYDVKQTFLEELKKNEQYELF  475
            ++    ++  D+ VYGKGAKRAVP+ +V+ EH+ARKV VL D K   L+ L  +EQ +L+
Sbjct  417  RIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLY  476

Query  476  TELELPLARVLADMEVKGVKVDTERLRNMGEELAGRLKEMEQEIYKLAGTEFNINSPKQL  535
             ++ELPLA VLA ME+ G+KV+   L++M+E+    +  + QEIY +AG EFNINSPKQL
Sbjct  477  QNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQL  536

Query  536  GVILFEDLNLP--VIKKTKTGYSTSADVLDKLMDRHEIIPNILHYRQLGKLNSTYIEGLL  593
            G ILFE ++LP  + KKTKTGYST+ DVL++L     I+++IL+YRQ+ KL+STY+ GL 
Sbjct  537  GSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQ  596

Query  594  KVVHEDSSKIHTRFNQVLTQTGRLSSTDPNLQNIPIRLEEGRKIRQAFVPSEEGWIMYAA  653
              +  D+ KIHTR+ Q LTQTGRLSS DPNLQNIPIRLE+GR IR+AF PS+E+ ++ ++
Sbjct  597  DYILADG-KIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSS  655

Query  654  DYSQIELRVLAHIANDPGLVEAFQHDMDIHTKTAMDVFGVGKD-EVTSNMRRQAKAVNFG  712
            DYSQIELRVLAHI+ D  L+ AF+++ DIHT TAM VFG++K  +VT+N RR+AKAVNFG
Sbjct  656  DYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFG  715

Query  713  IVYGISDYGLSQNLGITRKAAAEFIEKYLESFPGVQEYMDEIVKDAKQKGYVVTLLNRRR  772
            IVYGISD+GLS+NLGITRK +  +I+ Y+E +PG++ YM+++V++AK+KGYV TL++RRR
Sbjct  716  IVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRR  775

Query  773  YIPEITSRNFNLRSFAERTAMNTPIQGSaadiikkamiimadRLEEEGLQARLLLQVHDE  832
             +P+I SRNFN+RSFAERTA+N+PIQGSAADI+K AMI +   L+  G++A++LLQVHDE
Sbjct  776  ELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDE  835

Query  833  LIFEAPKEEIEKLEKLVPEVMEHAIELAVPLKVDYSYGPTWYDAK  877
            +++E P++E+  + KLV + ME A++LAVPL VD S G +WY+AK
Sbjct  836  IVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

249) Bsph_4111 in NC_010382


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  709 bits (2680),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 452/884 (52%), Positives = 651/884 (74%), Gaps = 16/884 (1%)

Query  2    TKEKLLLLDGNSLAYRAFFAL----PLLTNDSGIHTNAVYGFTTMLQRILEEEQPTKILV  57
             K+KLLL+DG+S+A+RAFFAL      + N+SG+HTNA+YGF  ML++++   +PT +LV
Sbjct  3    NKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLV  62

Query  58   AFDAGKTTFRHETFTEYKGGRQKTPPELSEQFPYIRKLIDAYGIKQYEQDLYEADDIIGT  117
            AFDAGKTTFR E +++YK+GR KTP E+ EQF+YIR ++ A GI  YE + YEADDIIGT
Sbjct  63   AFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGT  122

Query  118  LAKEASSQDM--DVIIVSGDRDLTQLATEQVTVYITKKGITEIERNTPAFIAEKYGLTPL  175
            L K A   ++  DV IVSGD+DL QL+ E+  V I+KKG++E+E  TPA++ EK GLTP 
Sbjct  123  LDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPN  182

Query  176  QIIDMKGLMGDSSDNIPGVPGVGEKTAVKLLKEHGSVEALYEAMDTLKASKMKEKLVANE  235
            Q+ID+K+LMGD SDNIPGV  +GEKT++KLL E GS+E++YE +D +K+SKMKE+L+ + 
Sbjct  183  QFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDR  242

Query  236  EQAIMSKKLATIYTDAPITISLTDLAYNGPNEEELMNVWRELGFKSLLEKSDFTVQEQEQ  295
            +QA++SK LATI T +PITI+L D+ YNGP+   L +   E++F  L       + ++  
Sbjct  243  DQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEPV  302

Query  296  TPFDFEQVQEVRQEDLQDVMAVHVELENEHYHTCALLGMALSDGTKTQYIPFEIAA-KSD  354
            + + +++V +V  + +        E   ++YH  A++G A ++G +  Y + +++   +D
Sbjct  303  AVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQI-YASTDLSLLATD  361

Query  355  ILRRWLEDSSKIKYMSDSKASKAALKRAGIQLAGVDFDLVLASYINNPGLSGDDVATLAR  414
             +++ ++ +    Y  D K SK  L + GI+L +  +D  LA+Y+ +  + +++++T+AR
Sbjct  362  SFKQVFQKPI-ATY--DFKRSKVLLSHLGIELVAPSYDARLANYLLST-VEDNELSTIAR  417

Query  415  ELGYYDVQADETVYGKGAKRAVPEIDKLAQHVSRKAYAVWSLQPKLEALLKENEQFDLYK  474
             +    ++ D+TVYGKGAKRAVP+ D L +H++RK   +   ++++   L  +EQ+DLY+
Sbjct  418  IFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQ  477

Query  475  ELELPLAAILGEMESEGITVNRATLEKMGQELNDKLVVLEQEIYAEAGETFNINSPKQLG  534
            ++ELPLA +L+ ME EGI VNRATL+ M+++ +  +  L QEIY  AG+ FNINSPKQLG
Sbjct  478  NIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLG  537

Query  535  VILFDKLGLP--VIKKTKTGYSTAADVLEKLKSEHAIIEYILLYRQLGKLQSTYIEGLLK  592
             ILF+K+ LP  + KKTKTGYSTA DVLE+L +  +I+  IL YRQ+ KLQSTY+ GL +
Sbjct  538  SILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGL-Q  596

Query  593  EIHEKDSKVHTRFQQALTATGRLSSTDPNLQNIPIRLEEGRKIRQAFVPSKEDWILFSAD  652
            +    D+K+HTR+ Q LT TGRLSS DPNLQNIPIRLE+GR IR+AF PS ED +L+S+D
Sbjct  597  DYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSD  656

Query  653  YSQIELRVLAHMSEDKNLVEAFREGMDVHTRTAMDVFHVS-EEEVDSNMRRAAKAVNFGI  711
            YSQIELRVLAH+S D +L+ AF EG D+HT TAM VF +    +V +N RR AKAVNFGI
Sbjct  657  YSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGI  716

Query  712  VYGISDYGLSQNLDITRKEAATFIEKYFASFPGVKQYMDDIVQNAKFNGYVTTILNRRRY  771
            VYGISD+GLS+NL+ITRK++ ++I+ YF  +PG+K YM+++V++AK +GYV T+++RRR 
Sbjct  717  VYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRE  776

Query  772  LPDITSSNFNLRSFAERTAMNTPIQGSAADIIKKAMIDMDARLKKENMQAKLLLQVHDEL  831
            LPDI S NFN+RSFAERTA+N+PIQGSAADI+K AMI++D  L+    +AK+LLQVHDE+
Sbjct  777  LPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEI  836

Query  832  IFEAPKEEIAMLEKIVPEVMENAIELSVPLKVDFNHGSTWYEAK  875
            ++E P++E++ + K+V + ME A++L+VPL VD + G +WYEAK
Sbjct  837  VLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

250) polA in NC_017196


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  709 bits (2682),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 441/889 (50%), Positives = 648/889 (73%), Gaps = 18/889 (2%)

Query  1    MTERKKLVLVDGNSLAYRAFFAL----PLLSNDKGVHTNAVYGFAMILMKMLEDEKPTHM  56
            M +++KL+L+DG+S+A+RAFFAL      + N+ G+HTNA+YGF ++L  M+   +PTH+
Sbjct  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60

Query  57   LVAFDAGKTTFRHGTFKEYKGGRQKTPPELSEQMPFIRELLDAYQISRYELEQYEADDII  116
            LVAFDAGKTTFR   + +YK+GR KTP E+ EQ ++IRE+L A  I+ YELE+YEADDII
Sbjct  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120

Query  117  GTLAKSAEKDG--FEVKVFSGDKDLTQLATDKTTVAITRKGITDVEFYTPEHVKEKYGLT  174
            GTL K AE+    F+V + SGDKDL QL+ ++T V I++KG+++ E +TP  + EK GLT
Sbjct  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180

Query  175  PEQIIDMKGLMGDSSDNIPGVPGVGEKTAIKLLKQFDSVEKLLESIDEVSGkklkeklee  234
            P+Q+ID+K+LMGD SDNIPGV  +GEKT++KLL +F+S+E + E ID     K+KE+L +
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  235  fkDQALMSKELATIMTDAPIEVSVSALEYQGFNREQVIAIFKDLGFNTLLERLGEDSAEA  294
             +DQA++SK LATI T +PI +++  + Y+G +   +  ++ +++F  L   L+ + ++ 
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQ-  299

Query  295  EQDQSLEDINVKTVTDVTSDILVSPSAFVVEQIGDNYHEEPILGFSIVNETGAYFIPKDT  354
               +++  I+ + VT+V++D++ +   F  E + DNYH E+I+GF+  +    Y     +
Sbjct  300  ---EPVAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLS  356

Query  355  AVESEVFKEWVENDDQKKWVFDSKRAVVALRWQGIELKGAEFDTLLAAYIINPGNSYDDV  414
             + ++ FK+  ++       +D KR+ V L   GIEL ++ +D+ LA Y+++  +  +++
Sbjct  357  LLATDSFKQVFQKPIA---TYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NEL  412

Query  415  ASVAKDYGLHIVSSDESVYGKGAKRAVPSEDVLSEHLGRKALAIQSLREKLVQELENNDQ  474
            +++A+ +    +  D++VYGKGAKRAVP  DVL EHL+RK   +   + ++++ L  ++Q
Sbjct  413  STIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQ  472

Query  475  LELFEELEMPLALILGEMESTGVKVDVDRLKRMGEELGAKLKEYEEKIHEIAGEPFNINS  534
            L+L++++E+PLA +L+ ME  G+KV+   L+ M+E+    +    + I ++AG+ FNINS
Sbjct  473  LDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINS  532

Query  535  PKQLGVILFEKIGLP--VVKKTKTGYSTSADVLEKLADKHDIVDYILQYRQIGKLQSTYI  592
            PKQLG ILFEK+ LP  + KKTKTGYST+ DVLE+LA    IV  IL+YRQI KLQSTY+
Sbjct  533  PKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYV  592

Query  593  EGLLKVTRPDSHKVHTRFNQALTQTGRLSSTDPNLQNIPIRLEEGRKIRQAFVPSEKDWL  652
             GL     +D+ K+HTR+ Q LTQTGRLSS DPNLQNIPIRLE+GR IR+AF PS+ D +
Sbjct  593  IGLQDYILADG-KIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAV  651

Query  653  IFAADYSQIELRVLAHISKDENLIEAFTNDMDIHTKTAMDVFHVAKD-EVTSAMRRQAKA  711
            ++++DYSQIELRVLAHIS DE+LI AF ++ DIHT TAM VF + K  +VT+  RR+AKA
Sbjct  652  LLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKA  711

Query  712  VNFGIVYGISDYGLSQNLGITRKEAGAFIDRYLESFQGVKAYMEDSVQEAKQKGYVTTLM  771
            VNFGIVYGISD+GLS+NLGITRK++ ++ID Y+E + G+KAYME+ V+EAK+KGYV TL 
Sbjct  712  VNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLF  771

Query  772  HRRRYIPELTSRNFNIRSFAERTAMNTPIQGSAADIIKKAMIDMAAKLKEKQLKARLLLQ  831
             RRR +P++ SRNFN+RSFAERTA+N+PIQGSAADI+K AMI++   L+   ++A++LLQ
Sbjct  772  KRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQ  831

Query  832  VHDELIFEAPKEEIEILEKLVPEVMEHALALDVPLKVDFASGPSWYDAK  880
            VHDE+++E P++E+  + KLV + ME A+ L VPL VD ++G SWY+AK
Sbjct  832  VHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

251) polA in NC_014319


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  708 bits (2679),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 450/896 (51%), Positives = 650/896 (73%), Gaps = 25/896 (2%)

Query  3    KKLLLIDGNSLAFRAFYAMYNQLDRMISHKGLHTNALVAFNNFLDQIVDPMQPDLAVVAW  62
            +KLLLIDG+S+AFRAF+A+YNQ+DR  +H GLHTNA+ +F+  LD+++  ++P   +VA 
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  63   DAASGKETFRGELFPEYKDGRSKAPSEFKEQFPYLREMVALHGLRNYEQPGLEADDIIGT  122
            DA  GK TFR E++++YK GR+K+P EF+EQF+Y+REM++  G+  YE    EADDIIGT
Sbjct  65   DA--GKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGT  122

Query  123  YSRLGEQAG--YTVIIVTGDQDLTQLATDNITVNVTKKGVTEIERYTPDYIMEKFNLKPL  180
              +++E++   + V IV+GD+DL QL+ +N  V+++KKGV+E+E +TP Y+MEK  L P 
Sbjct  123  LDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPN  182

Query  181  QIIEKKALTGDTSDNYPGVTKVGEKTALKLLAEYHDIDNLYAHVDDMKQSKLKDNLINDR  240
            Q+I+ KAL GD SDN PGVTK+GEKT+LKLL E+  ++ +Y H+D+ K SK+K+NLINDR
Sbjct  183  QFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDR  242

Query  241  QSAFCARKLATILTDAHLALPLEEIEYRGIDYDNLVTFYENLDFkkqlakikalqkSGQI  300
            + AF ++ LATI T + +++ L++I Y G D  +L  FY+++DF +    +     ++Q+
Sbjct  243  DQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGL-----ASQM  297

Query  301  SGSQTTVEKSINVIKLQDDNLQAVAMLGTKIAFHIEMIGQNYHIDDMVGFVIGSPATGYY  360
            +      + ++ VI  Q+    +  ++++   F +E + +NYH + ++GF  G  +   Y
Sbjct  298  P------QEPVAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWG-HGEQIY  350

Query  361  GSRDVTLLQRPELKSVIENAGIIKNVFNIKAQlillkrlgiklkgtkFDFLLVSYLLDTT  420
            +S D++LL    +K V++++      +++K   +LL +LGI L +  +D  L +YLL T 
Sbjct  351  ASTDLSLLATDSFKQVFQKP---IATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTV  407

Query  421  DNDNELATLAQRF-DLYMTSDEDIYGKGAKFAIPEDDARVLAHLANKADILMQVEQSAFD  479
            + DNEL+T+A+ F D+ +  D+ +YGKGAK A+P+ D  +L HLA K  +L++     +D
Sbjct  408  E-DNELSTIARIFTDISLEEDDTVYGKGAKRAVPDKDV-LLEHLARKVKVLLDSKSQMLD  465

Query  480  ALQEHEQTHLYTEIELPLAQVLADMEYQGIKIDQKRLRDIGSDLEGRIHAIEDAIYIEAG  539
             L  HEQ +LY +IELPLA+VLA ME +GIK+++  L+D++ +    I+A+ + IY  AG
Sbjct  466  KLTAHEQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAG  525

Query  540  EKFNINSPKQLGVLLFEKMGLP--VVKRTKTGYSTAVDVLEKLAAQAPIVDHILQYRQLA  597
            + FNINSPKQLG +LFEKM LP  + K+TKTGYSTAVDVLE+LA+ APIV  IL+YRQ++
Sbjct  526  QEFNINSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQIT  585

Query  598  KLKSTYVEGLLTVVHDQDSKIHTRFLQTLTQTGRLSSVDPNLQNIPMRTEEGRQIRTAFV  657
            KL+STYV GL   +   D+KIHTR++Q LTQTGRLSSVDPNLQNIP+R E+GR IR AF 
Sbjct  586  KLQSTYVIGLQDYILA-DGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFT  644

Query  658  PSEPNWQIVGADYSQIELRVLAHMTGDKNMQRAFLNGEDIHAETARAVFGLKDDAPVDAL  717
            PS+ +  ++++DYSQIELRVLAH++GD ++  AF +G DIH+ TA  VFG+   A V A 
Sbjct  645  PSHEDAVLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTAN  704

Query  718  MRRTAKAVNFGIVYGISDFGLANNLGISRGEAKSFIDTYFKEFPQIHAWMAKIKEIAHEQ  777
             RR AKAVNFGIVYGISDFGL+NNLGI+R ++KS+IDTYF  +P I A M ++   A ++
Sbjct  705  DRRNAKAVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDK  764

Query  778  GFVETIAKRRRYLPEIGSKNFNLRSFAERTAMNSPIQGSAADIIKIAMIKVADALQEHHM  837
            G+VET+ KRRR LP+I S+NFN+RSFAERTA+NSPIQGSAADI+KIAMI++  ALQ    
Sbjct  765  GYVETLFKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGF  824

Query  838  QARMLLQVHDELIFEAPIDEIQELTELVTNVMDSAVVLDVPMRVESHYGNTWYDAK  893
            +A+MLLQVHDE+++E P DE+  +  LV + M++AV L VP+ V+   G++WY+AK
Sbjct  825  RAKMLLQVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

252) polA in NC_000964


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  708 bits (2677),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 442/890 (50%), Positives = 652/890 (74%), Gaps = 20/890 (2%)

Query  1    MTERKKLVLVDGNSLAYRAFFAL----PLLSNDKGVHTNAVYGFAMILMKMLEDEKPTHM  56
            M +++KL+L+DG+S+A+RAFFAL      + N+ G+HTNA+YGF ++L  M+   +PTH+
Sbjct  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60

Query  57   LVAFDAGKTTFRHGTFKEYKGGRQKTPPELSEQMPFIRELLDAYQISRYELEQYEADDII  116
            LVAFDAGKTTFR   + +YK+GR KTP E+ EQ ++IRE+L A  I+ YELE+YEADDII
Sbjct  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120

Query  117  GTLAKSAEKDG--FEVKVFSGDKDLTQLATDKTTVAITRKGITDVEFYTPEHVKEKYGLT  174
            GTL K AE+    F+V + SGDKDL QL+ ++T V I++KG+++ E +TP  + EK GLT
Sbjct  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180

Query  175  PEQIIDMKGLMGDSSDNIPGVPGVGEKTAIKLLKQFDSVEKLLESIDEVSGkklkeklee  234
            P+Q+ID+K+LMGD SDNIPGV  +GEKT++KLL +F+S+E + E ID     K+KE+L +
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  235  fkDQALMSKELATIMTDAPIEVSVSGLEYQGFNREQVIAIFKDLGFNTLLERLGEDSAEA  294
             +DQA++SK LATI T +PI +++ ++ Y+G +   +  ++ +++F  L   L+ + ++ 
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQ-  299

Query  295  EQDQSLEDINVKTVTDVTSDILVSPSAFVVEQIGDNYHEEPILGFSIVNETGAYFIPKDI  354
               +++  I+ + VT+V++D++ +   F  E + DNYH E+I+GF+  +    Y  + D+
Sbjct  300  ---EPVAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIY-ASTDL  355

Query  355  AV-ESEVFKEWVENDEQKKWVFDSKRAVVALRWQGIELKGAEFDTLLAAYIINPGNSYDD  413
            ++  ++ FK+  ++       +D KR+ V L   GIEL ++ +D+ LA Y+++  +  ++
Sbjct  356  SLLATDSFKQVFQKPIA---TYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NE  411

Query  414  VASVAKDYGLHIVSSDESVYGKGAKRAVPSEDVLSEHLGRKALAIQSLREKLVQELENND  473
            ++++A+ +    +  D++VYGKGAKRAVP  DVL EHL+RK   +   + ++++ L  ++
Sbjct  412  LSTIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHE  471

Query  474  QLELFEELEMPLALILGEMESTGVKVDVDRLKRMGEELGAKLKEYEEKIHEIAGEPFNIN  533
            QL+L++++E+PLA +L+ ME  G+KV+   L+ M+E+    +    + I ++AG+ FNIN
Sbjct  472  QLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNIN  531

Query  534  SPKQLGVILFEKIGLP--VVKKTKTGYSTSADVLEKLADKHDIVDYILQYRQIGKLQSTY  591
            SPKQLG ILFEK+ LP  + KKTKTGYST+ DVLE+LA    IV  IL+YRQI KLQSTY
Sbjct  532  SPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTY  591

Query  592  IEGLLKVTRPDSHKVHTRFNQALTQTGRLSSTDPNLQNIPIRLEEGRKIRQAFVPSEKDW  651
            + GL     +D+ K+HTR+ Q LTQTGRLSS DPNLQNIPIRLE+GR IR+AF PS+ D 
Sbjct  592  VIGLQDYILADG-KIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDA  650

Query  652  LIFAADYSQIELRVLAHISKDENLIEAFTNDMDIHTKTAMDVFHVAKD-EVTSAMRRQAK  710
            +++++DYSQIELRVLAHIS DE+LI AF ++ DIHT TAM VF + K  +VT+  RR+AK
Sbjct  651  VLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAK  710

Query  711  AVNFGIVYGISDYGLSQNLGITRKEAGAFIDRYLESFQGVKAYMEDSVQEAKQKGYVTTL  770
            AVNFGIVYGISD+GLS+NLGITRK++ ++ID Y+E + G+KAYME+ V+EAK+KGYV TL
Sbjct  711  AVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETL  770

Query  771  MHRRRYIPELTSRNFNIRSFAERTAMNTPIQGSAADIIKKAMIDMAAKLKEKQLKARLLL  830
              RRR +P++ SRNFN+RSFAERTA+N+PIQGSAADI+K AMI++   L+   ++A++LL
Sbjct  771  FKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLL  830

Query  831  QVHDELIFEAPKEEIEILEKLVPEVMEHALALDVPLKVDFASGPSWYDAK  880
            QVHDE+++E P++E+  + KLV + ME A+ L VPL VD ++G SWY+AK
Sbjct  831  QVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

253) polA in NC_020507


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  708 bits (2677),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 442/890 (50%), Positives = 652/890 (74%), Gaps = 20/890 (2%)

Query  1    MTERKKLVLVDGNSLAYRAFFAL----PLLSNDKGVHTNAVYGFAMILMKMLEDEKPTHM  56
            M +++KL+L+DG+S+A+RAFFAL      + N+ G+HTNA+YGF ++L  M+   +PTH+
Sbjct  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60

Query  57   LVAFDAGKTTFRHGTFKEYKGGRQKTPPELSEQMPFIRELLDAYQISRYELEQYEADDII  116
            LVAFDAGKTTFR   + +YK+GR KTP E+ EQ ++IRE+L A  I+ YELE+YEADDII
Sbjct  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120

Query  117  GTLAKSAEKDG--FEVKVFSGDKDLTQLATDKTTVAITRKGITDVEFYTPEHVKEKYGLT  174
            GTL K AE+    F+V + SGDKDL QL+ ++T V I++KG+++ E +TP  + EK GLT
Sbjct  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180

Query  175  PEQIIDMKGLMGDSSDNIPGVPGVGEKTAIKLLKQFDSVEKLLESIDEVSGkklkeklee  234
            P+Q+ID+K+LMGD SDNIPGV  +GEKT++KLL +F+S+E + E ID     K+KE+L +
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  235  fkDQALMSKELATIMTDAPIEVSVSGLEYQGFNREQVIAIFKDLGFNTLLERLGEDSAEA  294
             +DQA++SK LATI T +PI +++ ++ Y+G +   +  ++ +++F  L   L+ + ++ 
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQ-  299

Query  295  EQDQSLEDINVKTVTDVTSDILVSPSAFVVEQIGDNYHEEPILGFSIVNETGAYFIPKDI  354
               +++  I+ + VT+V++D++ +   F  E + DNYH E+I+GF+  +    Y  + D+
Sbjct  300  ---EPVAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIY-ASTDL  355

Query  355  AV-ESEVFKEWVENDEQKKWVFDSKRAVVALRWQGIELKGAEFDTLLAAYIINPGNSYDD  413
            ++  ++ FK+  ++       +D KR+ V L   GIEL ++ +D+ LA Y+++  +  ++
Sbjct  356  SLLATDSFKQVFQKPIA---TYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NE  411

Query  414  VASVAKDYGLHIVSSDESVYGKGAKRAVPSEDVLSEHLGRKALAIQSLREKLVQELENND  473
            ++++A+ +    +  D++VYGKGAKRAVP  DVL EHL+RK   +   + ++++ L  ++
Sbjct  412  LSTIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHE  471

Query  474  QLELFEELEMPLALILGEMESTGVKVDVDRLKRMGEELGAKLKEYEEKIHEIAGEPFNIN  533
            QL+L++++E+PLA +L+ ME  G+KV+   L+ M+E+    +    + I ++AG+ FNIN
Sbjct  472  QLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNIN  531

Query  534  SPKQLGVILFEKIGLP--VVKKTKTGYSTSADVLEKLADKHDIVDYILQYRQIGKLQSTY  591
            SPKQLG ILFEK+ LP  + KKTKTGYST+ DVLE+LA    IV  IL+YRQI KLQSTY
Sbjct  532  SPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTY  591

Query  592  IEGLLKVTRPDSHKVHTRFNQALTQTGRLSSTDPNLQNIPIRLEEGRKIRQAFVPSEKDW  651
            + GL     +D+ K+HTR+ Q LTQTGRLSS DPNLQNIPIRLE+GR IR+AF PS+ D 
Sbjct  592  VIGLQDYILADG-KIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDA  650

Query  652  LIFAADYSQIELRVLAHISKDENLIEAFTNDMDIHTKTAMDVFHVAKD-EVTSAMRRQAK  710
            +++++DYSQIELRVLAHIS DE+LI AF ++ DIHT TAM VF + K  +VT+  RR+AK
Sbjct  651  VLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAK  710

Query  711  AVNFGIVYGISDYGLSQNLGITRKEAGAFIDRYLESFQGVKAYMEDSVQEAKQKGYVTTL  770
            AVNFGIVYGISD+GLS+NLGITRK++ ++ID Y+E + G+KAYME+ V+EAK+KGYV TL
Sbjct  711  AVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETL  770

Query  771  MHRRRYIPELTSRNFNIRSFAERTAMNTPIQGSAADIIKKAMIDMAAKLKEKQLKARLLL  830
              RRR +P++ SRNFN+RSFAERTA+N+PIQGSAADI+K AMI++   L+   ++A++LL
Sbjct  771  FKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLL  830

Query  831  QVHDELIFEAPKEEIEILEKLVPEVMEHALALDVPLKVDFASGPSWYDAK  880
            QVHDE+++E P++E+  + KLV + ME A+ L VPL VD ++G SWY+AK
Sbjct  831  QVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

254) I653_13895 in NC_020832


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  708 bits (2676),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 442/890 (50%), Positives = 651/890 (74%), Gaps = 20/890 (2%)

Query  1    MTERKKLVLVDGNSLAYRAFFAL----PLLSNDKGVHTNAVYGFAMILMKMLEDEKPTHM  56
            M +++KL+L+DG+S+A+RAFFAL      + N+ G+HTNA+YGF ++L  M+   +PTH+
Sbjct  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60

Query  57   LVAFDAGKTTFRHGTFKEYKGGRQKTPPELSEQMPFIRELLDAYQISRYELEQYEADDII  116
            LVAFDAGKTTFR   + +YK+GR KTP E+ EQ ++IRE+L A  I+ YELE+YEADDII
Sbjct  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120

Query  117  GTLAKSAEKDG--FEVKVFSGDKDLTQLATDKTTVAITRKGITDVEFYTPEHVKEKYGLT  174
            GTL K AE+    F+V + SGDKDL QL+ ++T V I++KG+++ E +TP  + EK GLT
Sbjct  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180

Query  175  PEQIIDMKGLMGDSSDNIPGVPGVGEKTAIKLLKQFDSVEKLLESIDEVSGkklkeklee  234
            P+Q+ID+K+LMGD SDNIPGV  +GEKT++KLL +F+S+E + E ID     K+KE+L +
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  235  fkDQALMSKELATIMTDAPIEVSVSALEYQGFNREQVIAIFKDLGFNTLLERLGEDSAEA  294
             +DQA++SK LATI T +PI +++  + Y+G +   +  ++ +++F  L   L+ + ++ 
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQ-  299

Query  295  EQDQSLEDINVKTVTDVTSDILVSPSAFVVEQIGDNYHEEPILGFSIVNETGAYFIPKDI  354
               +++  I+ + VT+V++D++ +   F  E + DNYH E+I+GF+  +    Y  + D+
Sbjct  300  ---EPVAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIY-ASTDL  355

Query  355  AV-ESEVFKEWVENDDQKKWVFDSKRAVVALRWQGIELKGAEFDTLLAAYIINPGNSYDD  413
            ++  ++ FK+  ++       +D KR+ V L   GIEL ++ +D+ LA Y+++  +  ++
Sbjct  356  SLLATDSFKQVFQKPIA---TYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NE  411

Query  414  VASVAKDYGLHIVSSDESVYGKGAKRAVPSEDVLSEHLGRKALAIQSLREKLVQELENND  473
            ++++A+ +    +  D++VYGKGAKRAVP  DVL EHL+RK   +   + ++++ L  ++
Sbjct  412  LSTIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHE  471

Query  474  QLELFEELEMPLALILGEMESTGVKVDVDRLKRMGEELGAKLKEYEEKIHEIAGEPFNIN  533
            QL+L++++E+PLA +L+ ME  G+KV+   L+ M+E+    +    + I ++AG+ FNIN
Sbjct  472  QLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNIN  531

Query  534  SPKQLGVILFEKIGLP--VVKKTKTGYSTSADVLEKLADKHDIVDYILQYRQIGKLQSTY  591
            SPKQLG ILFEK+ LP  + KKTKTGYST+ DVLE+LA    IV  IL+YRQI KLQSTY
Sbjct  532  SPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTY  591

Query  592  IEGLLKVTRPDSHKVHTRFNQALTQTGRLSSTDPNLQNIPIRLEEGRKIRQAFVPSEKDW  651
            + GL     +D+ K+HTR+ Q LTQTGRLSS DPNLQNIPIRLE+GR IR+AF PS+ D 
Sbjct  592  VIGLQDYILADG-KIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDA  650

Query  652  LIFAADYSQIELRVLAHISKDENLIEAFTNDMDIHTKTAMDVFHVAKD-EVTSAMRRQAK  710
            +++++DYSQIELRVLAHIS DE+LI AF ++ DIHT TAM VF + K  +VT+  RR+AK
Sbjct  651  VLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAK  710

Query  711  AVNFGIVYGISDYGLSQNLGITRKEAGAFIDRYLESFQGVKAYMEDSVQEAKQKGYVTTL  770
            AVNFGIVYGISD+GLS+NLGITRK++ ++ID Y+E + G+KAYME+ V+EAK+KGYV TL
Sbjct  711  AVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETL  770

Query  771  MHRRRYIPELTSRNFNIRSFAERTAMNTPIQGSAADIIKKAMIDMAAKLKEKQLKARLLL  830
              RRR +P++ SRNFN+RSFAERTA+N+PIQGSAADI+K AMI++   L+   ++A++LL
Sbjct  771  FKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLL  830

Query  831  QVHDELIFEAPKEEIEILEKLVPEVMEHALALDVPLKVDFASGPSWYDAK  880
            QVHDE+++E P++E+  + KLV + ME A+ L VPL VD ++G SWY+AK
Sbjct  831  QVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

255) polA in NC_018520


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  708 bits (2677),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 442/890 (50%), Positives = 652/890 (74%), Gaps = 20/890 (2%)

Query  1    MTERKKLVLVDGNSLAYRAFFAL----PLLSNDKGVHTNAVYGFAMILMKMLEDEKPTHM  56
            M +++KL+L+DG+S+A+RAFFAL      + N+ G+HTNA+YGF ++L  M+   +PTH+
Sbjct  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60

Query  57   LVAFDAGKTTFRHGTFKEYKGGRQKTPPELSEQMPFIRELLDAYQISRYELEQYEADDII  116
            LVAFDAGKTTFR   + +YK+GR KTP E+ EQ ++IRE+L A  I+ YELE+YEADDII
Sbjct  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120

Query  117  GTLAKSAEKDG--FEVKVFSGDKDLTQLATDKTTVAITRKGITDVEFYTPEHVKEKYGLT  174
            GTL K AE+    F+V + SGDKDL QL+ ++T V I++KG+++ E +TP  + EK GLT
Sbjct  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180

Query  175  PEQIIDMKGLMGDSSDNIPGVPGVGEKTAIKLLKQFDSVEKLLESIDEVSGkklkeklee  234
            P+Q+ID+K+LMGD SDNIPGV  +GEKT++KLL +F+S+E + E ID     K+KE+L +
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  235  fkDQALMSKELATIMTDAPIEVSVSGLEYQGFNREQVIAIFKDLGFNTLLERLGEDSAEA  294
             +DQA++SK LATI T +PI +++ ++ Y+G +   +  ++ +++F  L   L+ + ++ 
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQ-  299

Query  295  EQDQSLEDINVKTVTDVTSDILVSPSAFVVEQIGDNYHEEPILGFSIVNETGAYFIPKDI  354
               +++  I+ + VT+V++D++ +   F  E + DNYH E+I+GF+  +    Y  + D+
Sbjct  300  ---EPVAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIY-ASTDL  355

Query  355  AV-ESEVFKEWVENDEQKKWVFDSKRAVVALRWQGIELKGAEFDTLLAAYIINPGNSYDD  413
            ++  ++ FK+  ++       +D KR+ V L   GIEL ++ +D+ LA Y+++  +  ++
Sbjct  356  SLLATDSFKQVFQKPIA---TYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NE  411

Query  414  VASVAKDYGLHIVSSDESVYGKGAKRAVPSEDVLSEHLGRKALAIQSLREKLVQELENND  473
            ++++A+ +    +  D++VYGKGAKRAVP  DVL EHL+RK   +   + ++++ L  ++
Sbjct  412  LSTIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHE  471

Query  474  QLELFEELEMPLALILGEMESTGVKVDVDRLKRMGEELGAKLKEYEEKIHEIAGEPFNIN  533
            QL+L++++E+PLA +L+ ME  G+KV+   L+ M+E+    +    + I ++AG+ FNIN
Sbjct  472  QLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNIN  531

Query  534  SPKQLGVILFEKIGLP--VVKKTKTGYSTSADVLEKLADKHDIVDYILQYRQIGKLQSTY  591
            SPKQLG ILFEK+ LP  + KKTKTGYST+ DVLE+LA    IV  IL+YRQI KLQSTY
Sbjct  532  SPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTY  591

Query  592  IEGLLKVTRPDSHKVHTRFNQALTQTGRLSSTDPNLQNIPIRLEEGRKIRQAFVPSEKDW  651
            + GL     +D+ K+HTR+ Q LTQTGRLSS DPNLQNIPIRLE+GR IR+AF PS+ D 
Sbjct  592  VIGLQDYILADG-KIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDA  650

Query  652  LIFAADYSQIELRVLAHISKDENLIEAFTNDMDIHTKTAMDVFHVAKD-EVTSAMRRQAK  710
            +++++DYSQIELRVLAHIS DE+LI AF ++ DIHT TAM VF + K  +VT+  RR+AK
Sbjct  651  VLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAK  710

Query  711  AVNFGIVYGISDYGLSQNLGITRKEAGAFIDRYLESFQGVKAYMEDSVQEAKQKGYVTTL  770
            AVNFGIVYGISD+GLS+NLGITRK++ ++ID Y+E + G+KAYME+ V+EAK+KGYV TL
Sbjct  711  AVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETL  770

Query  771  MHRRRYIPELTSRNFNIRSFAERTAMNTPIQGSAADIIKKAMIDMAAKLKEKQLKARLLL  830
              RRR +P++ SRNFN+RSFAERTA+N+PIQGSAADI+K AMI++   L+   ++A++LL
Sbjct  771  FKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLL  830

Query  831  QVHDELIFEAPKEEIEILEKLVPEVMEHALALDVPLKVDFASGPSWYDAK  880
            QVHDE+++E P++E+  + KLV + ME A+ L VPL VD ++G SWY+AK
Sbjct  831  QVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

256) polA in NC_020244


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  708 bits (2676),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 442/890 (50%), Positives = 651/890 (74%), Gaps = 20/890 (2%)

Query  1    MTERKKLVLVDGNSLAYRAFFAL----PLLSNDKGVHTNAVYGFAMILMKMLEDEKPTHM  56
            M +++KL+L+DG+S+A+RAFFAL      + N+ G+HTNA+YGF ++L  M+   +PTH+
Sbjct  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60

Query  57   LVAFDAGKTTFRHGTFKEYKGGRQKTPPELSEQMPFIRELLDAYQISRYELEQYEADDII  116
            LVAFDAGKTTFR   + +YK+GR KTP E+ EQ ++IRE+L A  I+ YELE+YEADDII
Sbjct  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120

Query  117  GTLAKSAEKDG--FEVKVFSGDKDLTQLATDKTTVAITRKGITDVEFYTPEHVKEKYGLT  174
            GTL K AE+    F+V + SGDKDL QL+ ++T V I++KG+++ E +TP  + EK GLT
Sbjct  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180

Query  175  PEQIIDMKGLMGDSSDNIPGVPGVGEKTAIKLLKQFDSVEKLLESIDEVSGkklkeklee  234
            P+Q+ID+K+LMGD SDNIPGV  +GEKT++KLL +F+S+E + E ID     K+KE+L +
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  235  fkDQALMSKELATIMTDAPIEVSVSALEYQGFNREQVIAIFKDLGFNTLLERLGEDSAEA  294
             +DQA++SK LATI T +PI +++  + Y+G +   +  ++ +++F  L   L+ + ++ 
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQ-  299

Query  295  EQDQSLEDINVKTVTDVTSDILVSPSAFVVEQIGDNYHEEPILGFSIVNETGAYFIPKDI  354
               +++  I+ + VT+V++D++ +   F  E + DNYH E+I+GF+  +    Y  + D+
Sbjct  300  ---EPVAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIY-ASTDL  355

Query  355  AV-ESEVFKEWVENDDQKKWVFDSKRAVVALRWQGIELKGAEFDTLLAAYIINPGNSYDD  413
            ++  ++ FK+  ++       +D KR+ V L   GIEL ++ +D+ LA Y+++  +  ++
Sbjct  356  SLLATDSFKQVFQKPIA---TYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NE  411

Query  414  VASVAKDYGLHIVSSDESVYGKGAKRAVPSEDVLSEHLGRKALAIQSLREKLVQELENND  473
            ++++A+ +    +  D++VYGKGAKRAVP  DVL EHL+RK   +   + ++++ L  ++
Sbjct  412  LSTIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHE  471

Query  474  QLELFEELEMPLALILGEMESTGVKVDVDRLKRMGEELGAKLKEYEEKIHEIAGEPFNIN  533
            QL+L++++E+PLA +L+ ME  G+KV+   L+ M+E+    +    + I ++AG+ FNIN
Sbjct  472  QLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNIN  531

Query  534  SPKQLGVILFEKIGLP--VVKKTKTGYSTSADVLEKLADKHDIVDYILQYRQIGKLQSTY  591
            SPKQLG ILFEK+ LP  + KKTKTGYST+ DVLE+LA    IV  IL+YRQI KLQSTY
Sbjct  532  SPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTY  591

Query  592  IEGLLKVTRPDSHKVHTRFNQALTQTGRLSSTDPNLQNIPIRLEEGRKIRQAFVPSEKDW  651
            + GL     +D+ K+HTR+ Q LTQTGRLSS DPNLQNIPIRLE+GR IR+AF PS+ D 
Sbjct  592  VIGLQDYILADG-KIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDA  650

Query  652  LIFAADYSQIELRVLAHISKDENLIEAFTNDMDIHTKTAMDVFHVAKD-EVTSAMRRQAK  710
            +++++DYSQIELRVLAHIS DE+LI AF ++ DIHT TAM VF + K  +VT+  RR+AK
Sbjct  651  VLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAK  710

Query  711  AVNFGIVYGISDYGLSQNLGITRKEAGAFIDRYLESFQGVKAYMEDSVQEAKQKGYVTTL  770
            AVNFGIVYGISD+GLS+NLGITRK++ ++ID Y+E + G+KAYME+ V+EAK+KGYV TL
Sbjct  711  AVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETL  770

Query  771  MHRRRYIPELTSRNFNIRSFAERTAMNTPIQGSAADIIKKAMIDMAAKLKEKQLKARLLL  830
              RRR +P++ SRNFN+RSFAERTA+N+PIQGSAADI+K AMI++   L+   ++A++LL
Sbjct  771  FKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLL  830

Query  831  QVHDELIFEAPKEEIEILEKLVPEVMEHALALDVPLKVDFASGPSWYDAK  880
            QVHDE+++E P++E+  + KLV + ME A+ L VPL VD ++G SWY+AK
Sbjct  831  QVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

257) SPSINT_1449 in NC_014925


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  708 bits (2679),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 431/891 (49%), Positives = 649/891 (73%), Gaps = 32/891 (3%)

Query  2    DKLILIDGNSLSFRAFYAL----PLLKNKAGIHTNAVYGFARLLEKIIKEEQPTHFLVAF  57
            +KL+LIDG+S++FRAF+AL      +KN +G+HTNA+YGF  +L+ ++K  +PTH LVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  58   DAGKTTFRHETYQDYKGGRQKTPPELSEQFPYIRQLIDAYQIQRYELENYEADDIIGTLS  117
            DAGKTTFR E Y DYK+GR KTP E+ EQF+YIR+++ A  I  YELE+YEADDIIGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  118  READQAGM--QTIIITGDRDLTQLATDQVTIYYTKKGVTDVDHYTPQFIAEKYNGLKPSQ  175
            + A+++ +  +  I++GD+DL QL+ ++  +  +KKGV++ +++TP ++ EK  GL P+Q
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEK-MGLTPNQ  183

Query  176  IIDLKGLMGDSSDNIPGVAGVGEKTAMKLLNQFGTVEGVYDHIEEVSGKKLKEKLENSHD  235
            +IDLK+LMGD SDNIPGV+ +GEKT++KLL++FG++EG+Y+HI+     K+KE+L N +D
Sbjct  184  FIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRD  243

Query  236  DALMSKTLATINCDSPITVSLEDTRLPQKMDESAKIELFKSLEFRQLLDGMDVE-ADNAT  294
            +A++SKTLATIN  SPIT++L+D       D ++  +++  ++F QL  G+  + ++++ 
Sbjct  244  QAFLSKTLATINTASPITIGLDDIVYNGP-DVASLSQFYDEMDFVQLKKGLASQMPQEPV  302

Query  295  ASRDFVPTTNMSKVDFTQLSEAAIHVEVAGPNYLKDELLKFG------LYDGEQYVVIPF  348
            A   +   TN+S   F+  +E  +  E    NY ++ ++ F+      +Y + +  +++ 
Sbjct  303  AVISYQEVTNVSADLFS--AEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLAT  360

Query  349  DKVNE-YPELVAWLEDETTQKWVHDAKKTYIAMKRSDIAIENVVFDTMLASYIIDPSRTI  407
            D  ++ +   +A            D K++ + + + +I +    +D+ LA+Y++      
Sbjct  361  DSFKQVFQKPIA----------TYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-  409

Query  408  EDVHSVMTHFDQTFVQDDVSVYGKGKSFHIPEDGVLDKHIASILDAIHVVQPQMMTILEA  467
            +++ ++   F +  +++D +VYGKG    +P+ +VL  H+A  +  +   ++QM+  L A
Sbjct  410  NELSTIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTA  469

Query  468  HEQTSLLSEIELPLALILSEMEYIGIHTDIDTLKEMETVIQTELDQLIEQIHEQAGEKFN  527
            HEQ  L  +IELPLA +L+ ME  GI  +  TL++M    +  ++ L ++I + AG+ FN
Sbjct  470  HEQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFN  529

Query  528  INSPKQLGVILFEKLELP--VIKKTKTGYSTAVDVLEKLQNAHPIIDNILTYRTLSKLQS  585
            INSPKQLG ILFEK++LP  + KKTKTGYSTAVDVLE+L    PI+ +IL YR ++KLQS
Sbjct  530  INSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQS  589

Query  586  TYVEGLQKVIWDDGRIHTRFNQTLAQTGRLSSVDPNLQNIPIRLEEGRKIRKAFKSTHED  645
            TYV GLQ  I  DG+IHTR+ Q L+QTGRLSSVDPNLQNIPIRLE+GR IRKAF ++HED
Sbjct  590  TYVIGLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHED  649

Query  646  YVILAADYSQIELRVLAHITGDPTLQQAFNDNEDVHTTTAMKVFNVA-ADEVTSLMRRQA  704
             V+L++DYSQIELRVLAHI+GD  L  AFN+  D+HT+TAM+VF +  A +VT+  RR+A
Sbjct  650  AVLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNA  709

Query  705  KAVNFGIVYGISDYGLSQSLGITRKEAQRFIDDYLNHFPGVKDYMDNIVQDAKQQGYVET  764
            KAVNFGIVYGISD+GLS++LGITRK+++ +ID Y++++PG+K YM+N+V++AK++GYVET
Sbjct  710  KAVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVET  769

Query  765  LLKRRRYIPDITSRNFNLRGFAERTAMNSPIQGSAADIIKLAMVQFHREVQKTSFKAQLL  824
            L+KRRR +PDI SRNFN+R+FAERTA+NSPIQGSAADI+K+AM+++++ +Q  +F+A++L
Sbjct  770  LFKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKML  829

Query  825  LQVHDELIFEVPKDEVDEFGKFVEEIMAHALQLDVPLSVESDYGKTWYDAK  875
            LQVHDE+++EVP+DE+  + K+V + M  A++L VPL V+   G++WY+AK
Sbjct  830  LQVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

258) BSn5_05375 in NC_014976


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  707 bits (2675),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 443/890 (50%), Positives = 651/890 (74%), Gaps = 20/890 (2%)

Query  1    MTERKKLVLVDGNSLAYRAFFAL----PLLSNDKGVHTNAVYGFAMILMKMLEDEKPTHM  56
            M +++KL+L+DG+S+A+RAFFAL      + N+ G+HTNA+YGF ++L  M+   +PTH+
Sbjct  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60

Query  57   LVAFDAGKTTFRHGTFKEYKGGRQKTPPELSEQMPFIRELLDAYQISRYELEQYEADDII  116
            LVAFDAGKTTFR   + +YK+GR KTP E+ EQ ++IRE+L A  I+ YELE+YEADDII
Sbjct  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120

Query  117  GTLAKSAEKDG--FEVKVFSGDKDLTQLATDKTTVAITRKGITDVEFYTPEHVKEKYGLT  174
            GTL K AE+    F+V + SGDKDL QL+ ++T V I++KG+++ E +TP  + EK GLT
Sbjct  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180

Query  175  PEQIIDMKGLMGDSSDNIPGVPGVGEKTAIKLLKQFDSVEKLLESIDEVSGkklkeklee  234
            P+Q+ID+K+LMGD SDNIPGV  +GEKT++KLL +F+S+E + E ID     K+KE+L +
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  235  fkDQALMSKELATIMTDAPIEVSVSGLEYQGFNREQVIAIFKDLGFNTLLERLGEGSAEA  294
             +DQA++SK LATI T +PI +++ ++ Y+G +   +  ++ +++F     +L  G A  
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFV----QLKKGLASQ  296

Query  295  EQDQSLEDINVKTVTDVTSDILVSPSAFVVEQIGDNYHEEPILGFSIVNETGAYFIPKDI  354
              ++++  I+ + VT+V++D++ +   F  E + DNYH E+I+GF+  +    Y  + D+
Sbjct  297  MPQEPVAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIY-ASTDL  355

Query  355  AV-ESEVFKEWVENDDQKKWVFDSKRAVVALRWQGIELKGAEFDTLLAAYIINPGNSYDD  413
            ++  ++ FK+  ++       +D KR+ V L   GIEL ++ +D+ LA Y+++  +  ++
Sbjct  356  SLLATDSFKQVFQKPIA---TYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NE  411

Query  414  VASVAKDYGLHIVSSDESVYGKGAKRAVPSEDVLSEHLGRKALAIQSLREKLVQELENND  473
            ++++A+ +    +  D++VYGKGAKRAVP  DVL EHL+RK   +   + ++++ L  ++
Sbjct  412  LSTIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHE  471

Query  474  QLELFEELEMPLALILGEMESTGVKVDVDRLKRMGEELGTKLKEYEEKIHEIAGEPFNIN  533
            QL+L++++E+PLA +L+ ME  G+KV+   L+ M+E+    +    + I ++AG+ FNIN
Sbjct  472  QLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNIN  531

Query  534  SPKQLGVILFEKIGLP--VVKKTKTGYSTSADVLEKLADKHDIVDYILQYRQIGKLQSTY  591
            SPKQLG ILFEK+ LP  + KKTKTGYST+ DVLE+LA    IV  IL+YRQI KLQSTY
Sbjct  532  SPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTY  591

Query  592  IEGLLKVTRPDSHKVHTRFNQALTQTGRLSSTDPNLQNIPIRLEEGRKIRQAFVPSEKDW  651
            + GL     +D+ K+HTR+ Q LTQTGRLSS DPNLQNIPIRLE+GR IR+AF PS+ D 
Sbjct  592  VIGLQDYILADG-KIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDA  650

Query  652  LIFAADYSQIELRVLAHISKDENLIEAFTNDMDIHTKTAMDVFHVAKD-EVTSAMRRQAK  710
            +++++DYSQIELRVLAHIS DE+LI AF ++ DIHT TAM VF + K  +VT+  RR+AK
Sbjct  651  VLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAK  710

Query  711  AVNFGIVYGISDYGLSQNLGITRKEAGAFIDRYLESFQGVKAYMEDSVQEAKQKGYVTTL  770
            AVNFGIVYGISD+GLS+NLGITRK++ ++ID Y+E + G+KAYME+ V+EAK+KGYV TL
Sbjct  711  AVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETL  770

Query  771  MHRRRYIPELTSRNFNIRSFAERTAMNTPIQGSAADIIKKAMIDMAAKLKEKQLKARLLL  830
              RRR +P++ SRNFN+RSFAERTA+N+PIQGSAADI+K AMI++   L+   ++A++LL
Sbjct  771  FKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLL  830

Query  831  QVHDELIFEAPKEEIEILEKLVPEVMEHALALDVPLKVDFASGPSWYDAK  880
            QVHDE+++E P++E+  + KLV + ME A+ L VPL VD ++G SWY+AK
Sbjct  831  QVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

259) A7A1_0772 in NC_019896


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  707 bits (2674),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 442/890 (50%), Positives = 651/890 (74%), Gaps = 20/890 (2%)

Query  1    MTERKKLVLVDGNSLAYRAFFAL----PLLSNDKGVHTNAVYGFAMILMKMLEDEKPTHM  56
            M +++KL+L+DG+S+A+RAFFAL      + N+ G+HTNA+YGF ++L  M+   +PTH+
Sbjct  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60

Query  57   LVAFDAGKTTFRHGTFKEYKGGRQKTPPELSEQMPFIRELLDAYQISRYELEQYEADDII  116
            LVAFDAGKTTFR   + +YK+GR KTP E+ EQ ++IRE+L A  I+ YELE+YEADDII
Sbjct  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120

Query  117  GTLAKSAEKDG--FEVKVFSGDKDLTQLATDKTTVAITRKGITDVEFYTPEHVKEKYGLT  174
            GTL K AE+    F+V + SGDKDL QL+ ++T V I++KG+++ E +TP  + EK GLT
Sbjct  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180

Query  175  PEQIIDMKGLMGDSSDNIPGVPGVGEKTAIKLLKQFDSVEKLLESIDEVSGkklkeklee  234
            P+Q+ID+K+LMGD SDNIPGV  +GEKT++KLL +F+S+E + E ID     K+KE+L +
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  235  fkDQALMSKELATIMTDAPIEVSVSGLEYQGFNREQVIAIFKDLGFNTLLERLGEDSAEA  294
             +DQA++SK LATI T +PI +++ ++ Y+G +   +  ++ +++F  L   L+ + ++ 
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQ-  299

Query  295  EQDQSLEDINVKTVTDVTSDILVSPSAFVVEQIGDNYHEEPILGFSIVNETGAYFIPKDI  354
               +++  I+ + VT+V++D++ +   F  E + DNYH E+I+GF+  +    Y  + D+
Sbjct  300  ---EPVAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIY-ASTDL  355

Query  355  AV-ESEVFKEWVENDEQKKWVFDSKRAVVALRWQGIELKGAEFDTLLAAYIINPGNSYDD  413
            ++  ++ FK+  ++       +D KR+ V L   GIEL ++ +D+ LA Y+++  +  ++
Sbjct  356  SLLATDSFKQVFQKPIA---TYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NE  411

Query  414  VASVAKDYGLHIVSSDESVYGKGAKRAVPSEDVLSEHLGRKALAIQSLREKLVQELENND  473
            ++++A+ +    +  D++VYGKGAKRAVP  DVL EHL+RK   +   + ++++ L  ++
Sbjct  412  LSTIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHE  471

Query  474  QLELFEELEMPLALILGEMESTGVKVDVDRLKRMGEELGAKLKEYEEKIHEIAGEPFNIN  533
            QL+L++++E+PLA +L+ ME  G+KV+   L+ M+E+    +    + I ++AG+ FNIN
Sbjct  472  QLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNIN  531

Query  534  SPKQLGVILFEKIGLP--VVKKTKTGYSTSADVLEKLADKHDIVDYILQYRQIGKLQSTY  591
            SPKQLG ILFEK+ LP  + KKTKTGYST+ DVLE+LA    IV  IL+YRQI KLQSTY
Sbjct  532  SPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTY  591

Query  592  IEGLLKVTRPDSHKVHTRFNQALTQTGRLSSTDPNLQNIPIRLEEGRKIRQAFVPSEKDW  651
            + GL     +D+ K+HTR+ Q LTQTGRLSS DPNLQNIPIRLE+GR IR+AF PS+ D 
Sbjct  592  VIGLQDYILADG-KIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDA  650

Query  652  LIFAADYSQIELRVLAHISKDENLIEAFTNDMDIHTKTAMDVFHVAKD-EVTSAMRRQAK  710
            +++++DYSQIELRVLAHIS DE+LI AF ++ DIHT TAM VF + K  +VT+  RR+AK
Sbjct  651  VLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAK  710

Query  711  AVNFGIVYGISDYGLSQNLGITRKEAGAFIDRYLESFQGVKAYMEDSVQEAKQKGYVTTL  770
            AVNFGIVYGISD+GLS+NLGITRK++ ++ID Y+E + G+KAYME+ V+EAK+KGYV TL
Sbjct  711  AVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETL  770

Query  771  MHRRRYIPELTSRNFNIRSFAERTAMNTPIQGSAADIIKKAMIDMAAKLKEKQLKARLLL  830
              RRR +P++ SRNFN+RSFAERTA+N+PIQGSAADI+K AMI++   L+   ++A++LL
Sbjct  771  FKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLL  830

Query  831  QVHDELIFEAPREEIEILEKLVPEVMEHALALDVPLKVDFASGPSWYDAK  880
            QVHDE+++E P +E+  + KLV + ME A+ L VPL VD ++G SWY+AK
Sbjct  831  QVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

260) Bcoa_2523 in NC_016023


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  705 bits (2668),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 454/883 (52%), Positives = 646/883 (74%), Gaps = 16/883 (1%)

Query  2    KKLILIDGNSIAYRAFFAL----PLLNNDKGIHTNAVYGFTMMLSKILEEEKPTHILVAF  57
            +KL+LIDG+S+A+RAFFAL      ++N+ G+HTNA+YGF +ML  ++   +PTH+LVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  58   DAGKTTFRHETYSEYKGTRQKTPPELSEQFPLIRELLDAHGIERYELENYEADDIIGTLS  117
            DAGKTTFR E Y++YK+ R KTP E+ EQF+ IRE+L A GI  YELE+YEADDIIGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  118  KKAE--EEGFIVKVISGDKDMTQLVSPKTTVMITRKGITDMEAYTPAHVEEKYGLTPHQI  175
            K AE  E  F V ++SGDKD+ QL   +T V I++KG+++ E +TPA + EK GLTP+Q+
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  176  IDMKGLMGDSSDNIPGVPGIGEKTAIKLLKQFPTVEELLDHIGEVSGKKLQEKLEANKEQ  235
            ID+K+LMGD SDNIPGV  IGEKT++KLL +F ++E + +HI+     K++E+L  +++Q
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRDQ  244

Query  236  ALMSKELATIHRDIPLSISIEQAAYKHADPEKLRHLYQELGFKSMLEKMGGDTPTEEKPA  295
            A++SK LATI+   P++I++++  Y+ +D   L ++Y+E++F  +   ++++ P E   +
Sbjct  245  AFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQE---P  301

Query  296  LEAISFSIAEDITDNLFADVSSFYVEILDENYHTGEIIGFGLKNEKGLFFLRAEDALSSE  355
            +  IS+    +++ +LF+    FY E L +NYH   IIGF+  +   ++       L+++
Sbjct  302  VAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLATD  361

Query  356  AFKKWVEDESKIKHVYDAKRSIVALRRYGIDLRGTDFDLLLVSYLLNPSDTVEDFASVAK  415
            +FK+  +   K    YD KRS V L + GI+L +  +D  L +YLL+  +  ++++++A+
Sbjct  362  SFKQVFQ---KPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NELSTIAR  417

Query  416  THDYGNVETDEAVYGKGAKRKLPEEKRYAEHISRKAEAIDALCEPCTKALKNNGQlelfe  475
                 ++E D++VYGKGAKR +P+     EH++RK   +          L  + QL+L++
Sbjct  418  IFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQ  477

Query  476  qlelplslilADMEYTGVKVDTDRLKEMGEEFKLRLHEIEQRIYSMAGTEFNINSPKQLG  535
            ++ELPL+ +LA ME  G+KV+   L++M+E+ K+ ++ + Q IY MAG EFNINSPKQLG
Sbjct  478  NIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLG  537

Query  536  VILFEKMGLPV--IKKTKTGYSTSADVLEKLEPAHEIVREILHYRQLGKLQSTYIEGLLK  593
             ILFEKM LP+   KKTKTGYST+ DVLE+L P   IV  IL+YRQ+ KLQSTY+ GL  
Sbjct  538  SILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQD  597

Query  594  VVHQDGKVHTRFNQALTQTGRLSSTDPNLQNIPIRMEEGRKIRQAFVPSEEGWLIFSSDY  653
             +  DGK+HTR+ Q LTQTGRLSS DPNLQNIPIR+E+GR IR+AF PS+E+ +++SSDY
Sbjct  598  YILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDY  657

Query  654  SQVELRVLAHISGDEKLIEAFREGMDIHTKTAMEVFHV-KAEEVTSEMRRQAKTVNFGIV  712
            SQ+ELRVLAHISGDE LI AF EG DIHT TAM VF + KA +VT++ RR+AK+VNFGIV
Sbjct  658  SQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIV  717

Query  713  YGISDYGLSQNLGISRKEAGEFIKRYFASYPRVKEYMDEIVREAKQKGYVSTLLKRRRYL  772
            YGISD+GLS+NLGI+RK++  +I  YF  YP +K YM+++VREAK+KGYV TL+KRRR L
Sbjct  718  YGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRREL  777

Query  773  PEITSRNFNLRSFAERTAMNTPIQGSAADIIKKAMIDMakrlkkeklrarlllQVHDeli  832
            P+I SRNFN+RSFAERTA+N+PIQGSAADI+K AMI++ K L+   +RA++LLQVHDE++
Sbjct  778  PDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIV  837

Query  833  feapeeeieVLKEIVPEVMEHAVDLAAPLKVDSAYGPTWFDAK  875
            +E P++E+  +K +V + ME AVDLA PL VD + G +W++AK
Sbjct  838  LEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

261) M493_14160 in NC_022080


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  704 bits (2661),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 445/884 (51%), Positives = 634/884 (72%), Gaps = 16/884 (1%)

Query  2    KNKLVLIDGNSVAYRAFFAL----PLLHNDKGIHTNAVYGFTMMLNKILTEEQPTHLLVA  57
            KNKL+LIDG+SVA+RAFFAL      + N+ G+HTNA+YGF +ML+ ++   +PTH+LVA
Sbjct  4    KNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVA  63

Query  58   FDAGKTTFRHETFQEYKGGRQQTPPELSEQFPLLRELLKAYRIPVYELDRYEADDIIGTL  117
            FDAGKTTFR E + +YK+GR +TP E+ EQF+ +RE+L A  I+ YEL++YEADDIIGTL
Sbjct  64   FDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTL  123

Query  118  ASRAEQEG--FEVKVISGDRDLTQLASPHVTVDITKKGITDIEPYTPETVREKYGLTPEQ  175
               AE+    F+V ++SGD+DL QL+  +  V+I+KKG++++E +TP  + EK GLTP+Q
Sbjct  124  DKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQ  183

Query  176  IVDLKGLMGDKSDNIPGVPGIGEKTAVKLLKQFGTVENVLASIDEIKGEKLKENLRQYGE  235
            ++DLK+LMGDKSDNIPGV  IGEKT++KLL +FG++E +   ID +K  K+KENL +  +
Sbjct  184  FIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRD  243

Query  236  LALLSKRLAAIRRDAPVELTLDDIIYEGQDREKVIALFKELGFQSFLEKMAAPAAEHEEL  295
             A+LSK LA+I   +P+ + LDDI+Y+G D   +  ++ E++F  +  K + ++   +E 
Sbjct  244  QAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQL--KKGLASQMPQEP  301

Query  296  LVEMEFVMADDITEEMLTDKAALVVEVMEENYHDAPIVGIALVNEHGRFFLRPEKALADP  355
            +  + +    +++ ++++    +  E + +NYH  +I+G+A  + +  +       LA  
Sbjct  302  VAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLATD  361

Query  356  AFLAWLGDATKKKTMFDSKRAVVSLKWKGIELRGVAFDlllaaylldpaqaagdvaavaN  415
            +F   +    K  + +D KR+ V L   GIEL + ++D  LA YLL   +     +    
Sbjct  362  SFKQVF---QKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIARI  418

Query  416  MKQYGAVRPDEAVYGKGAKRSLPDEPVLAEHLVRKAAAIWALEKPLMDDLRHNEQDELLT  475
              +  ++  D++VYGKGAKR++PD  VL EHL RK   +      ++D L  +EQ +L  
Sbjct  419  FTD-ISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQ  477

Query  476  KLEQPLAAILADMEFTGVKVDTKRLRQMGAELTEQLRAVEQHIYELAGQEFNINSPKQLG  535
            ++E PLA +LA ME+ G+KV+   L++M+ +    + A+ Q+IY++AGQEFNINSPKQLG
Sbjct  478  NIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLG  537

Query  536  VILFDKLQLP--VLKKTKTGYSTSADVLEKLAPHHEIVENILHYRQLGKLQSTYIEGLLK  593
             ILF+K+QLP  + KKTKTGYST+ DVLE+LAP   IV +IL+YRQ+ KLQSTY+ GL  
Sbjct  538  SILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQD  597

Query  594  VVHPDTNKVHTMFNQALTQTGRLSSAEPNLQNIPIRLEEGRKIRQAFVPSEPDWLIFAAD  653
             + +D  K+HT + Q LTQTGRLSS +PNLQNIPIRLE+GR IR+AF PS+ D +++++D
Sbjct  598  YILAD-GKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSD  656

Query  654  YSQIELRVLAHIADDDNLIEAFRRDLDIHTKTAMDIFHVN-EEDVTANMRRQAKAVNFGI  712
            YSQIELRVLAHI++D++LI AF  + DIHT TAM +F ++   DVTAN RR+AKAVNFGI
Sbjct  657  YSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGI  716

Query  713  VYGISDYGLAQNLNITRKEAAEFIERYFASFPGVKRYMENIVQEAKQKGYVTTLLHRRRY  772
            VYGISD+GL++NL ITRK++  +I+ YF  +PG+K YMEN+V+EAK+KGYV TL+ RRR 
Sbjct  717  VYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRE  776

Query  773  LPDITSRNFNVRSFAERTAMNTPIQGSAADIIKKAMIDLNARLKEEQLRARLLLQVHDEL  832
            LPDI SRNFNVRSFAERTA+N+PIQGSAADI+K AMI+L+  L+   +RA++LLQVHDE+
Sbjct  777  LPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEI  836

Query  833  ILEAPKEEVERLCRLVPEVMEQAVTLNVPLKVDYHYGPTWYDAK  876
            +LE P++E+  + +LV + ME AV L VPL VD   G +WY+AK
Sbjct  837  VLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

262) LGMK_03120 in NC_015734


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  704 bits (2664),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 450/898 (51%), Positives = 646/898 (72%), Gaps = 27/898 (3%)

Query  3    KKLLLIDGNSLAFRAFYAMYNQLDRMISHKGLHTNALVAFNNFLDQIVDPMQPDLAVVAW  62
            +KLLLIDG+S+AFRAF+A+YNQ+DR  +H GLHTNA+ +F+  LD+++  ++P   +VA 
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  63   DAASGKETFRGELFPEYKDGRSKTPSEFQEQFPYLREMVALHGLRNYEQPGLEADDIIGT  122
            DA  GK TFR E++++YK GR+KTP EF+EQF+Y+REM++  G+  YE    EADDIIGT
Sbjct  65   DA--GKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGT  122

Query  123  FSRMGEKAG--YSVTIITGDQDLTQLAtekvtvnvtkkgvtEIEQYTPSYIMDKFGLKPL  180
            + +M+E++   + VTI++GD+DL QL+ E+  V+++KKGV+E+E++TP+Y+M+K GL P 
Sbjct  123  LDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPN  182

Query  181  QIIEKKALTGDTSDNYPGVTKVGEKTALKLLAEYHDIDNLYAHIDDMKQSKLKENLIKDR  240
            Q+I+ KAL GD SDN PGVTK+GEKT+LKLL E+  ++ +Y HID+ K SK+KENLI+DR
Sbjct  183  QFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDR  242

Query  241  EAAFCARQLATILTDATLELPLEEIEYRHIDYDKLVTFYEDLDFkqqlakikalqkSGQI  300
            + AF ++ LATI T + + + L++I Y   D   L  FY+++DF              Q+
Sbjct  243  DQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFV-------------QL  289

Query  301  IGSQTQTSVEKAINVVTLQEDNLQAVAMLGNKIALHIEMAGSNYHIDDMIGFVIGSPATG  360
              + +    + ++ V++ QE    +  +++    + +E    NYH + +IGF  G  +  
Sbjct  290  KKGLASQMPQEPVAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWG-HGEQ  348

Query  361  YYGSRDVSLLQRPELRSVIENAAIIKNVFNVKAQFVLFKRLGMTLRGVEFDFLLAAYLLD  420
             Y+S D+SLL    ++ V++++      ++ K   VL+ +LG+ L +  +D  LA YLL 
Sbjct  349  IYASTDLSLLATDSFKQVFQKPI---ATYDFKRSKVLLSHLGIELVAPSYDARLANYLLS  405

Query  421  TTDNDNELSTLAQRF-DFYVTPDEDIYGKGAKYAVPEEASRVLVHLAHKADVLMQLEQPA  479
            T + DNELST+A+ F D+ +  D+ +YGKGAK AVP+    +L HLA+K  VL++     
Sbjct  406  TVE-DNELSTIARIFTDISLEEDDTVYGKGAKRAVPDKDV-LLEHLARKVKVLLDSKSQM  463

Query  480  FAALQDHEQTHLYTEIELPLAHVLADMEYRGIKIDQTRLREIGTDLEERIDTIKEAIFIE  539
            +  L  HEQ +LY +IELPLA+VLA ME  GIK++++ L++++ +    I+++ + I+  
Sbjct  464  LDKLTAHEQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDM  523

Query  540  AGEVFNINSPKQLGILLFEKMGLP--VIKKTKTGYSTAVDVLEKLAPQAPIVDHILQYRQ  597
            AG+ FNINSPKQLG +LFEKM LP  + KKTKTGYSTAVDVLE+LAP APIV  IL+YRQ
Sbjct  524  AGQEFNINSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQ  583

Query  598  LAKLKSTYVDGLLSVVHEKDSKIHTRFLQTLTQTGRLSSIDPNLQNIPMRTEAGRKIRTA  657
            ++KL+STYV GL   +   D+KIHTR++Q LTQTGRLSS+DPNLQNIP+R E GR IR A
Sbjct  584  ITKLQSTYVIGLQDYILA-DGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKA  642

Query  658  FVPSQPDWQIFGADYSQIELRVLAHMTGDKNMQQAFLNGEDIHAETARAVFGLDDNVPVD  717
            F PS+ D  ++++DYSQIELRVLAH++GD ++  AF +G DIH+ TA  VFG+D    V 
Sbjct  643  FTPSHEDAVLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVT  702

Query  718  PLMRRTAKAVNFGIVYGISDFGLANNLGISRAEAKRFIETYFQEFPKIHEWMTQIKAKAH  777
            +  RR AKAVNFGIVYGISDFGL+NNLGI+R ++K +I+TYF+ +P I   M ++   A 
Sbjct  703  ANDRRNAKAVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAK  762

Query  778  EQGFVETIAKRRRYLPEIGSKNFNLRSFAERTAMNSPIQGSAADIIKIAMIKVADALQEN  837
            ++G+VET+ KRRR LP+I S+NFN+RSFAERTA+NSPIQGSAADI+KIAMI++  ALQ  
Sbjct  763  DKGYVETLFKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAG  822

Query  838  GMQARMLLQVHDELIFEAPSDEIAELSELVTRVMDSAVVLDVPMLVESHSGNTWYEAK  895
            G +A+MLLQVHDE+++E P+DE++ +  LV   M++AV L VP+ V+  +G++WYEAK
Sbjct  823  GFRAKMLLQVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

263) MY9_2900 in NC_017743


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  704 bits (2663),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 439/890 (50%), Positives = 651/890 (74%), Gaps = 20/890 (2%)

Query  1    MTERKKLVLVDGNSLAYRAFFAL----PLLSNDKGVHTNAVYGFAMILMKMLEDEKPTHM  56
            M +++KL+L+DG+S+A+RAFFAL      + N+ G+HTNA+YGF ++L  M+   +PTH+
Sbjct  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60

Query  57   LVAFDAGKTTFRHGTFKEYKGGRQKTPPELSEQMPFIRELLDAYQISRYELDQYEADDII  116
            LVAFDAGKTTFR   + +YK+GR KTP E+ EQ ++IRE+L A  I+ YEL++YEADDII
Sbjct  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120

Query  117  GTLAKSAEKDG--FEVKVFSGDKDLTQLATDNTTVAITRKGITDVEFYTPEHVKEKYGLT  174
            GTL K AE+    F+V + SGDKDL QL+ +NT V I++KG+++ E +TP  + EK GLT
Sbjct  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180

Query  175  PEQIIDMKGLMGDSSDNIPGVPGVGEKTAIKLLKQFDSVEKLLESIDEVSGkklkeklee  234
            P+Q+ID+K+LMGD SDNIPGV  +GEKT++KLL +F+S+E + E ID     K+KE+L +
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  235  fkDQALMSKELATIMTDAPIEVSVSGLEYQGFNREQVIAIFKDLGFNTLLERLGEDSAEA  294
             +DQA++SK LATI T +PI +++ ++ Y+G +   +  ++ +++F  L   L+ + ++ 
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQ-  299

Query  295  EQDQSLEDINVEIVTDVTSGILVSPSAFVVEQIGDNYHEEPILGFSIVNETGAYFIPKDI  354
               +++  I+ + VT+V+++++ +   F  E + DNYH E+I+GF+  +    Y  + D+
Sbjct  300  ---EPVAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIY-ASTDL  355

Query  355  AV-ESEVFKEWVENDEQKKWVFDSKRAVVALRWQGIELKGAEFDTLLAAYIINPGNSYDD  413
            ++  ++ FK+  ++       +D KR+ V L   GIEL ++ +D+ LA Y+++  +  ++
Sbjct  356  SLLATDSFKQVFQKPIA---TYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NE  411

Query  414  VASVAKDYGLHIVSSDESVYGKGAKRAVPSEDVLSEHLGRKALAIQSLREKLVQELENND  473
            ++++A+ +    +  D++VYGKGAKRAVP  DVL EHL+RK   +   + ++++ L  ++
Sbjct  412  LSTIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHE  471

Query  474  QLELFEELEMPLALILGEMESTGVKVDVDRLKRMGEELGAKLKEYEEKIHEIAGEPFNIN  533
            QL+L++++E+PLA +L+ ME  G+KV+   L+ M+E+    +    + I ++AG+ FNIN
Sbjct  472  QLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNIN  531

Query  534  SPKQLGVILFEKIGLP--VVKKTKTGYSTSADVLEKLADKHDIVDYILQYRQIGKLQSTY  591
            SPKQLG ILFEK+ LP  + KKTKTGYST+ DVLE+LA    IV  IL+YRQI KLQSTY
Sbjct  532  SPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTY  591

Query  592  IEGLLKVTRPDSHKVHTRFNQALTQTGRLSSTDPNLQNIPIRLEEGRKIRQAFVPSEKDW  651
            + GL     +D+ K+HTR+ Q LTQTGRLSS DPNLQNIPIRLE+GR IR+AF PS+ D 
Sbjct  592  VIGLQDYILADG-KIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDA  650

Query  652  LIFAADYSQIELRVLAHISKDENLIEAFTNDMDIHTKTAMDVFHVA-EDEVTSAMRRQAK  710
            +++++DYSQIELRVLAHIS DE+LI AF ++ DIHT TAM VF +    +VT+  RR+AK
Sbjct  651  VLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAK  710

Query  711  AVNFGIVYGISDYGLSQNLGITRKEAGAFIDRYLESFQGVKAYMEDSVQDAKQKGYVTTL  770
            AVNFGIVYGISD+GLS+NLGITRK++ ++ID Y+E + G+KAYME+ V++AK+KGYV TL
Sbjct  711  AVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETL  770

Query  771  MHRRRYIPELTSRNFNIRSFAERTAMNTPIQGSAADIIKKAMIDMAAKLKEKQLKARLLL  830
              RRR +P++ SRNFN+RSFAERTA+N+PIQGSAADI+K AMI++   L+   ++A++LL
Sbjct  771  FKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLL  830

Query  831  QVHDELIFEAPQEEIEILEKLVPEVMEHALALDVPLKVDFASGPSWYDAK  880
            QVHDE+++E P++E+  + KLV + ME A+ L VPL VD ++G SWY+AK
Sbjct  831  QVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

264) polA in NC_017195


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  704 bits (2664),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 442/890 (50%), Positives = 650/890 (74%), Gaps = 20/890 (2%)

Query  1    MTERKKLVLVDGNSLAYRAFFAL----PLLSNDKGVHTNAVYGFAMILMKMLEDEKPTHM  56
            M +++KL+L+DG+S+A+RAFFAL      + N+ G+HTNA+YGF ++L  M+   +PTH+
Sbjct  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60

Query  57   LVAFDAGKTTFRHGTFKEYKGGRQKTPPELSEQMPFIRELLDAYQISRYELEQYEADDII  116
            LVAFDAGKTTFR   + +YK+GR KTP E+ EQ ++IRE+L A  I+ YELE+YEADDII
Sbjct  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120

Query  117  GTLAKSAEKDG--FEVKVFSGDKDLTQLATDKTTVAITRKGITDVEFYTPEHVKEKYGLT  174
            GTL K AE+    F+V + SGDKDL QL+ ++T V I++KG+++ E +TP  + EK GLT
Sbjct  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180

Query  175  PEQIIDMKGLMGDSSDNIPGVPGVGEKTAIKLLKQFDSVEKLLESIDEVSGkklkeklee  234
            P+Q+ID+K+LMGD SDNIPGV  +GEKT++KLL +F+S+E + E ID     K+KE+L +
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  235  fkDQALMSKELATIMTDAPIEVSVSGLEYQGFNREQVIAIFKDLGFNTLLERLGEDSEEA  294
             +DQA++SK LATI T +PI +++ ++ Y+G +   +  ++ +++F  L   L+ +    
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQM---  297

Query  295  EQDQSLEDINVKTVTDVTSDILVSPSAFVVEQIGDNYHEEPILGFSIVNEMGAYFIPKDI  354
              ++++  I+ + VT+V++D++ +   F  E + DNYH E+I+GF+  +    Y  + D+
Sbjct  298  -PQEPVAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIY-ASTDL  355

Query  355  AV-ESEVFKEWVENDDQKKWVFDSKRAVVALRWQGIELKGAEFDTLLAAYIINPGNSYDD  413
            ++  ++ FK+  ++       +D KR+ V L   GIEL ++ +D+ LA Y+++  +  ++
Sbjct  356  SLLATDSFKQVFQKPIA---TYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NE  411

Query  414  VASVAKDYGLHIVSSDESVYGKGAKRAVPSEDVLSEHLGRKALAIQSLREKLVQELENND  473
            ++++A+ +    +  D++VYGKGAKRAVP  DVL EHL+RK   +   + ++++ L  ++
Sbjct  412  LSTIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHE  471

Query  474  QLELFEELEMPLALILGEMESTGVKVDVDRLKRMGEELGAKLKEYEEKIHEIAGEPFNIN  533
            QL+L++++E+PLA +L+ ME  G+KV+   L+ M+E+    +    + I ++AG+ FNIN
Sbjct  472  QLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNIN  531

Query  534  SPKQLGVILFEKIGLP--VVKKTKTGYSTSADVLEKLADKHDIVDYILQYRQIGKLQSTY  591
            SPKQLG ILFEK+ LP  + KKTKTGYST+ DVLE+LA    IV  IL+YRQI KLQSTY
Sbjct  532  SPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTY  591

Query  592  IEGLLKVTRKDSHKVHTRFNQALTQTGRLSSTDPNLQNIPIRLEEGRKIRQAFVPSEKDW  651
            + GL      D+ K+HTR+ Q LTQTGRLSS DPNLQNIPIRLE+GR IR+AF PS+ D 
Sbjct  592  VIGLQDYILADG-KIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDA  650

Query  652  LIFAADYSQIELRVLAHISKDENLIEAFTNDMDIHTKTAMDVFHVAKD-EVTSAMRRQAK  710
            +++++DYSQIELRVLAHIS DE+LI AF ++ DIHT TAM VF + K  +VT+  RR+AK
Sbjct  651  VLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAK  710

Query  711  AVNFGIVYGISDYGLSQNLGITRKEAGAFIDRYLESFQGVKAYMEDSVQEAKQKGYVTTL  770
            AVNFGIVYGISD+GLS+NLGITRK++ ++ID Y+E + G+KAYME+ V+EAK+KGYV TL
Sbjct  711  AVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETL  770

Query  771  MHRRRYIPELTSRNFNIRSFAERTAMNTPIQGSAADIIKKAMIDMAAKLKEKQLKARLLL  830
              RRR +P++ SRNFN+RSFAERTA+N+PIQGSAADI+K AMI++   L+   ++A++LL
Sbjct  771  FKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLL  830

Query  831  QVHDELIFEAPKEEIEILEKLVPEVMEHALALDVPLKVDFASGPSWYDAK  880
            QVHDE+++E P++E+  + KLV + ME A+ L VPL VD ++G SWY+AK
Sbjct  831  QVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

265) LKI_08995 in NC_014136


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  704 bits (2663),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 449/898 (50%), Positives = 646/898 (72%), Gaps = 27/898 (3%)

Query  3    KKLLLIDGNSLAFRAFYAMYNQLDRMISHKGLHTNALVAFNNFLDQIVDPMQPDLAVVAW  62
            +KLLLIDG+S+AFRAF+A+YNQ+DR  +H GLHTNA+ +F+  LD+++  ++P   +VA 
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  63   DAASGKETFRGELFPEYKDGRSKTPSEFQEQFPYLREMVALHGLRNYEQPGLEADDIIGT  122
            DA  GK TFR E++++YK GR+KTP EF+EQF+Y+REM++  G+  YE    EADDIIGT
Sbjct  65   DA--GKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGT  122

Query  123  FSRMGEKAG--YSVTIITGDQDLTQLAtekvtvnvtkkgvtEIEQYTPSYIMDKFGLKPL  180
            + +M+E++   + VTI++GD+DL QL+ E+  V+++KKGV+E+E++TP+Y+M+K GL P 
Sbjct  123  LDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPN  182

Query  181  QIIEKKALTGDTSDNYPGVTKVGEKTALKLLTEYHDIDNLYAHIDDMKQSKLKENLIKDR  240
            Q+I+ KAL GD SDN PGVTK+GEKT+LKLL E+  ++ +Y HID+ K SK+KENLI+DR
Sbjct  183  QFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDR  242

Query  241  EAAFCARQLATILTDATLELPLEEIEYRHIDYDKLVTFYEDLDFkqqlakikalqkSGQI  300
            + AF ++ LATI T + + + L++I Y   D   L  FY+++DF              Q+
Sbjct  243  DQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFV-------------QL  289

Query  301  IGSQTQTSVEKAINVVTLQEDNLQAVAMLGNKIALHIEMAGSNYHIDDMIGFVIGSPATG  360
              + +    + ++ V++ QE    +  +++    + +E    NYH + +IGF  G  +  
Sbjct  290  KKGLASQMPQEPVAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWG-HGEQ  348

Query  361  YYGSRDVSLLQRPELRSVIENAAIIKNVFNVKAQFVLFKRLGMTLRGVEFDFLLAAYLLD  420
             Y+S D+SLL    ++ V++++      ++ K   VL+ +LG+ L +  +D  LA YLL 
Sbjct  349  IYASTDLSLLATDSFKQVFQKPI---ATYDFKRSKVLLSHLGIELVAPSYDARLANYLLS  405

Query  421  TTDNDNELSTLAQRF-DFYVTPDEDIYGKGAKYAVPEETSRVLVHLAHKADVLMQLEQPA  479
            T + DNELST+A+ F D+ +  D+ +YGKGAK AVP+    +L HLA+K  VL++     
Sbjct  406  TVE-DNELSTIARIFTDISLEEDDTVYGKGAKRAVPDKDV-LLEHLARKVKVLLDSKSQM  463

Query  480  FAALQDHEQTHLYTEIELPLAHVLADMEYRGIKIDQTRLREIGTDLEERIDTIKEAIFIE  539
            +  L  HEQ +LY +IELPLA+VLA ME  GIK++++ L++++ +    I+++ + I+  
Sbjct  464  LDKLTAHEQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDM  523

Query  540  AGEVFNINSPKQLGILLFEKMGLP--VIKKTKTGYSTAVDVLEKLAPQAPIVDHILQYRQ  597
            AG+ FNINSPKQLG +LFEKM LP  + KKTKTGYSTAVDVLE+LAP APIV  IL+YRQ
Sbjct  524  AGQEFNINSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQ  583

Query  598  LAKLKSTYVDGLLSVVHEKDSKIHTRFLQTLTQTGRLSSIDPNLQNIPMRTEAGRKIRTA  657
            ++KL+STYV GL   +   D+KIHTR++Q LTQTGRLSS+DPNLQNIP+R E GR IR A
Sbjct  584  ITKLQSTYVIGLQDYILA-DGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKA  642

Query  658  FVPSQPDWQIFGADYSQIELRVLAHMTGDKNMQQAFLNGEDIHAETARAVFGLDDNVPVD  717
            F PS+ D  ++++DYSQIELRVLAH++GD ++  AF +G DIH+ TA  VFG+D    V 
Sbjct  643  FTPSHEDAVLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVT  702

Query  718  PLMRRTAKAVNFGIVYGISDFGLANNLGISRAEAKRFIETYFQEFPKIHEWMTQIKAKAH  777
            +  RR AKAVNFGIVYGISDFGL+NNLGI+R ++K +I+TYF+ +P I   M ++   A 
Sbjct  703  ANDRRNAKAVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAK  762

Query  778  EQGFIETIAKRRRYLPEIGSKNFNLRSFAERTAMNSPIQGSAADIIKIAMIKVADALQEN  837
            ++G++ET+ KRRR LP+I S+NFN+RSFAERTA+NSPIQGSAADI+KIAMI++  ALQ  
Sbjct  763  DKGYVETLFKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAG  822

Query  838  GMQARMLLQVHDELIFEAPSDEIAELSELVTRVMDSAVVLDVPMLVESHSGNTWYEAK  895
            G +A+MLLQVHDE+++E P+DE++ +  LV   M++AV L VP+ V+  +G++WYEAK
Sbjct  823  GFRAKMLLQVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

266) polA in NC_014479


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  701 bits (2652),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 437/890 (50%), Positives = 648/890 (73%), Gaps = 20/890 (2%)

Query  1    MTERKKLVLVDGNSLAYRAFFAL----PLLSNDKGVHTNAVYGFAMILMKMLEDEKPTHM  56
            M +++KL+L+DG+S+A+RAFFAL      + N+ G+HTNA+YGF ++L  M+   +PTH+
Sbjct  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60

Query  57   LVAFDAGKTTFRHGTFKEYKGGRQKTPPELSEQMPFIRELLDAYQISRYELEQYEADDII  116
            LVAFDAGKTTFR   + +YK+GR KTP E+ EQ ++IRE+L A  I+ YELE+YEADDII
Sbjct  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120

Query  117  GTLAKSAEKDG--FEVKVFSGDKDLTQLATDKTTVAITRKGITDVEFYTPEHVKEKYGLT  174
            GTL K AE+    F+V + SGDKDL QL+ ++T V I++KG+++ E +TP  + EK GLT
Sbjct  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180

Query  175  PEQIIDMKGLMGDSSDNIPGVPGVGEKTAIKLLKQFDSVEKLLESIDEVSGkklkeklee  234
            P+Q+ID+K+LMGD SDNIPGV  +GEKT++KLL +F+S+E + E ID     K+KE+L +
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  235  fkDQALMSKELATIMTDAPIEVSVSGLEYQGFNREQVIAIFKDLGFNTLLERLGEDSEEA  294
             +DQA++SK LATI T +PI +++ ++ Y+G +   +  ++ +++F  L   L+ +    
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQM---  297

Query  295  EQDQALEEIKVETVTDVTSGILVSPSAFVVEQIGDNYHEEPLLGFSIVNETGSYFIPKDI  354
              ++++  I  + VT+V+++++ +   F  E + DNYH E+++GF+  +    Y  + D+
Sbjct  298  -PQEPVAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIY-ASTDL  355

Query  355  AV-ESEVFKEWAENDEQKKWLFDSKRAVVALRWQGIELKGAEFDTLLAAYIINPGNSYDD  413
            ++  ++ FK+  ++       +D KR+ V L   GIEL ++ +D+ LA Y+++  +  ++
Sbjct  356  SLLATDSFKQVFQKPIAT---YDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NE  411

Query  414  VASVAKDYGLHIVSSDESVYGKGAKRAVPSEDVLSEHLVRKALAIQSLREKLVQELENND  473
            ++++A+ +    +  D++VYGKGAKRAVP  DVL EHL RK   +   + ++++ L  ++
Sbjct  412  LSTIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHE  471

Query  474  QLELFEELEMPLALILGEMESTGVKVDVDRLKRMGEELGAKLKEYEEKIHEIAGEPFNIN  533
            QL+L++++E+PLA +L+ ME  G+KV+   L+ M+E+    +    + I ++AG+ FNIN
Sbjct  472  QLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNIN  531

Query  534  SPKQLGVILFEKIGLP--VVKKTKTGYSTSADVLEKLADKHDIVDYILQYRQIGKLQSTY  591
            SPKQLG ILFEK+ LP  + KKTKTGYST+ DVLE+LA    IV  IL+YRQI KLQSTY
Sbjct  532  SPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTY  591

Query  592  IEGLLKVTRPDSHKVHTRFNQALTQTGRLSSTDPNLQNIPIRLEEGRKIRQAFVPSEKDW  651
            + GL     +D+ K+HTR+ Q LTQTGRLSS DPNLQNIPIRLE+GR IR+AF PS+ D 
Sbjct  592  VIGLQDYILADG-KIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDA  650

Query  652  LIFAADYSQIELRVLAHISKDQNLIEAFTNDMDIHTKTAMDVFHVA-EDEVTSAMRRQAK  710
            +++++DYSQIELRVLAHIS D++LI AF ++ DIHT TAM VF +    +VT+  RR+AK
Sbjct  651  VLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAK  710

Query  711  AVNFGIVYGISDYGLSQNLGITRKEAGAFIDQYLESFQGVKAYMEDSVQDAKQKGYVTTL  770
            AVNFGIVYGISD+GLS+NLGITRK++ ++ID Y+E + G+KAYME+ V++AK+KGYV TL
Sbjct  711  AVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETL  770

Query  771  MHRRRYIPELTSRNFNIRSFAERTAMNTPIQGSAADIIKKAMIDMAAKLKEKQLKARLLL  830
              RRR +P++ SRNFN+RSFAERTA+N+PIQGSAADI+K AMI++   L+   ++A++LL
Sbjct  771  FKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLL  830

Query  831  QVHDELIFEAPQEEIEILEKLVPEVMEHALALDVPLKVDFASGPSWYDAK  880
            QVHDE+++E P++E+  + KLV + ME A+ L VPL VD ++G SWY+AK
Sbjct  831  QVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

267) polA in NC_020210


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  700 bits (2646),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 449/885 (51%), Positives = 641/885 (73%), Gaps = 18/885 (2%)

Query  2    KKKLVLIDGSSVAYRAFFAL----PLLHNDKGIHTNAVYGFTMMLNKILAEEEPTHMLVA  57
            K+KL+LIDGSSVA+RAFFAL      + N+ G+HTNA+YGF +ML+ ++    PTH+LVA
Sbjct  4    KNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVA  63

Query  58   FDAGKTTFRHEAFQEYKGGRQQTPPELSEQFPLLRELLRAYRIPAYELENYEADDIIGTL  117
            FDAGKTTFR E + +YK+GR +TP E+ EQF+ +RE+L A  I+ YELE+YEADDIIGTL
Sbjct  64   FDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTL  123

Query  118  AARAEQEG--FEVKVISGDRDLTQLASPHVTVDITKKGITDIEPYTPETVREKYGLTPEQ  175
               AE+    F+V ++SGD+DL QL+  +  V+I+KKG++++E +TP  + EK GLTP+Q
Sbjct  124  DKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQ  183

Query  176  IVDLKGLMGDKSDNIPGVPGIGEKTAVKLLRQFGTVENVLASIDEIKGEKLKETLRQHRE  235
            ++DLK+LMGDKSDNIPGV  IGEKT++KLL++FG++E +   ID +K  K+KE L ++R+
Sbjct  184  FIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRD  243

Query  236  MALLSKKLAAIRRDAPVELSLDDIAYQGEDREKVVALFKELGFQSFLekmespsseeekp  295
             A+LSK LA+I   +P+ ++LDDI Y+G D   +  ++ E++F  +  K   +S   + P
Sbjct  244  QAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQL--KKGLASQMPQEP  301

Query  296  LAKMAFTLADRVTEEMLADKAALVVEVVEENYHDAPIVGIAVVNEHG-RFFLRPETALAD  354
            +A +++     V+ ++++    +  E + +NYH  +I+G+A    HG +++   + +L  
Sbjct  302  VAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFA--WGHGEQIYASTDLSLLA  359

Query  355  PQFVAWLGDETKKKSMFDSKRAAVALKWKGIELCGVSFdlllaaylldPAQGVDDVAAAA  414
             +  +      K  + +D KR+ V L   GIEL + S+D  LA YLL   ++ +++++ A
Sbjct  360  TD--SFKQVFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NELSTIA  416

Query  415  KMKQYEAVRPDEAVYGKGAKRAVPDEPVLAEHLVRKAAAIWALERPFLDELRRNEQDRLL  474
            ++    ++  D++VYGKGAKRAVPD  VL EHL RK   +       LD L  +EQ  L 
Sbjct  417  RIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLY  476

Query  475  VELEQPLSSILAEMEFAGVKVDTKRLEQMGEELAEQLGTVEQRIYELAGQEFNINSPKQL  534
             ++E PL+++LA ME+ G+KV+   L++M+E+    + ++ Q IY++AGQEFNINSPKQL
Sbjct  477  QNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQL  536

Query  535  GVILFEKLQLP--VLKKTKTGYSTSADVLEKLAPYHEIVENILHYRQLGKLQSTYIEGLL  592
            G ILFEK+QLP  + KKTKTGYST+ DVLE+LAP   IV +IL+YRQ+ KLQSTY+ GL 
Sbjct  537  GSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQ  596

Query  593  KVVRPDTKKVHTIFNQALTQTGRLSSTEPNLQNIPIRLEEGRKIRQAFVPSESDWLIFAA  652
              + +D K +HT + Q LTQTGRLSS +PNLQNIPIRLE+GR IR+AF PS+ D +++++
Sbjct  597  DYILADGK-IHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSS  655

Query  653  DYSQIELRVLAHIAEDDNLMEAFRRDLDIHTKTAMDIFQVS-EDEVTPNMRRQAKAVNFG  711
            DYSQIELRVLAHI+ D++L+ AF  + DIHT TAM +F +    +VT+N RR+AKAVNFG
Sbjct  656  DYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFG  715

Query  712  IVYGISDYGLAQNLNISRKEAAEFIERYFESFPGVKRYMENIVQEAKQKGYVTTLLHRRR  771
            IVYGISD+GL++NL I+RK++  +I+ YFE +PG+K YMEN+V+EAK+KGYV TL+ RRR
Sbjct  716  IVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRR  775

Query  772  YLPDITSRNFNVRSFAERMAMNTPIQGSAADIIKKAMIDLNARLKEERLQARLLLQVHDE  831
             LPDI SRNFNVRSFAER A+N+PIQGSAADI+K AMI+L+  L+   ++A++LLQVHDE
Sbjct  776  ELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDE  835

Query  832  LILEAPKEEMERLCRLVPEVMEQAVTLRVPLKVDYHYGSTWYDAK  876
            ++LE P++E+  + +LV + ME AV L VPL VD   G +WY+AK
Sbjct  836  IVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

268) polA in NC_006510


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  700 bits (2648),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 450/888 (51%), Positives = 643/888 (73%), Gaps = 18/888 (2%)

Query  1    MRLKKKLVLIDGSSVAYRAFFAL----PLLHNDKGIHTNAVYGFTMMLNKILAEEEPTHM  56
            M  K+KL+LIDGSSVA+RAFFAL      + N+ G+HTNA+YGF +ML+ ++    PTH+
Sbjct  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60

Query  57   LVAFDAGKTTFRHEAFQEYKGGRQQTPPELSEQFPLLRELLRAYRIPAYELENYEADDII  116
            LVAFDAGKTTFR E + +YK+GR +TP E+ EQF+ +RE+L A  I+ YELE+YEADDII
Sbjct  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120

Query  117  GTLAARAEQEG--FEVKVISGDRDLTQLASPHVTVDITKKGITDIEPYTPETVREKYGLT  174
            GTL   AE+    F+V ++SGD+DL QL+  +  V+I+KKG++++E +TP  + EK GLT
Sbjct  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180

Query  175  PEQIVDLKGLMGDKSDNIPGVPGIGEKTAVKLLRQFGTVENVLASIDEIKGEKLKETLRQ  234
            P+Q++DLK+LMGDKSDNIPGV  IGEKT++KLL++FG++E +   ID +K  K+KE L +
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  235  HREMALLSKKLAAIRRDAPVELSLDDIVYQGEDREKVVALFKELGFQSFLekmespssee  294
            +R+ A+LSK LA+I   +P+ ++LDDIVY+G D   +  ++ E++F  +  K   +S   
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQL--KKGLASQMP  298

Query  295  ekpLAKMAFTLADRVTEEMLADKAALVVEVVEENYHDAPIVGIAVVNEHG-RFFLRPETA  353
            + P+A +++     V+ ++++    +  E + +NYH  +I+G+A    HG +++   + +
Sbjct  299  QEPVAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFA--WGHGEQIYASTDLS  356

Query  354  LADPQFVAWLGDETKKKSMFDSKRAAVALKWKGIELCGVSFdlllaaylldPAQGVDDVA  413
            L   +  +      K  + +D KR+ V L   GIEL + S+D  LA YLL   ++ ++++
Sbjct  357  LLATD--SFKQVFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NELS  413

Query  414  AAAKMKQYEAVRPDEAVYGKGAKRAVPDEPVLAEHLVRKAAAIWELERPFLDELRRNEQD  473
            + A++    ++  D++VYGKGAKRAVPD  VL EHL RK   + +     LD L  +EQ 
Sbjct  414  TIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQL  473

Query  474  RLLVELEQPLSSILAEMEFAGVKVDTKRLEQMGKELAEQLGTVEQRIYELAGQEFNINSP  533
             L  ++E PL+++LA ME+ G+KV+   L++M+ +    + ++ Q IY++AGQEFNINSP
Sbjct  474  DLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSP  533

Query  534  KQLGVILFEKLQLP--VLKKTKTGYSTSADVLEKLAPYHEIVENILHYRQLGKLQSTYIE  591
            KQLG ILFEK+QLP  + KKTKTGYST+ DVLE+LAP   IV +IL+YRQ+ KLQSTY+ 
Sbjct  534  KQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVI  593

Query  592  GLLKVVRPDTKKVHTIFNQALTQTGRLSSTEPNLQNIPIRLEEGRKIRQAFVPSESDWLI  651
            GL   + +D K +HT + Q LTQTGRLSS +PNLQNIPIRLE+GR IR+AF PS+ D ++
Sbjct  594  GLQDYILADGK-IHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVL  652

Query  652  FAADYSQIELRVLAHIAEDDNLMEAFRRDLDIHTKTAMDIFQVS-EDEVTPNMRRQAKAV  710
            +++DYSQIELRVLAHI+ D++L+ AF  + DIHT TAM +F +    +VT+N RR+AKAV
Sbjct  653  LSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAV  712

Query  711  NFGIVYGISDYGLAQNLNISRKEAAEFIERYFESFPGVKRYMENIVQEAKQKGYVTTLLH  770
            NFGIVYGISD+GL++NL I+RK++  +I+ YFE +PG+K YMEN+V+EAK+KGYV TL+ 
Sbjct  713  NFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFK  772

Query  771  RRRYLPDITSRNFNVRSFAERMAMNTPIQGSAADIIKKAMIDLNARLKEERLQARLLLQV  830
            RRR LPDI SRNFNVRSFAER A+N+PIQGSAADI+K AMI+L+  L+   ++A++LLQV
Sbjct  773  RRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQV  832

Query  831  HDELILEAPKEEMERLCRLVPEVMEQAVTLRVPLKVDYHYGSTWYDAK  878
            HDE++LE P++E+  + +LV + ME AV L VPL VD   G +WY+AK
Sbjct  833  HDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

269) GTCCBUS3UF5_30750 in NC_016593


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  700 bits (2646),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 450/885 (51%), Positives = 641/885 (73%), Gaps = 18/885 (2%)

Query  2    KKKLVLIDGSSVAYRAFFAL----PLLHNDKGIHTNAVYGFTMMLNKILAEEEPTHMLVA  57
            K+KL+LIDGSSVA+RAFFAL      + N+ G+HTNA+YGF +ML+ ++    PTH+LVA
Sbjct  4    KNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVA  63

Query  58   FDAGKTTFRHEAFQEYKGGRQQTPPELSEQFPLLRELLRAYRIPAYELENYEADDIIGTL  117
            FDAGKTTFR E + +YK+GR +TP E+ EQF+ +RE+L A  I+ YELE+YEADDIIGTL
Sbjct  64   FDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTL  123

Query  118  AARAEQEG--FEVKVISGDRDLTQLASPHVTVDITKKGITDIEPYTPETVREKYGLTPEQ  175
               AE+    F+V ++SGD+DL QL+  +  V+I+KKG++++E +TP  + EK GLTP+Q
Sbjct  124  DKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQ  183

Query  176  IVDLKGLMGDKSDNIPGVPGIGEKTAVKLLKQFGTVENVLASIDEIKGEKLKETLRQHRE  235
            ++DLK+LMGDKSDNIPGV  IGEKT++KLL +FG++E +   ID +K  K+KE L ++R+
Sbjct  184  FIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRD  243

Query  236  MALLSKKLAAIRRDAPVELSLDDIVYQGEDREKVVALFKELGFQSFLekmespsseeekp  295
             A+LSK LA+I   +P+ ++LDDIVY+G D   +  ++ E++F  +  K   +S   + P
Sbjct  244  QAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQL--KKGLASQMPQEP  301

Query  296  LAKMAFTLADRVTEEMLADKAALVVEVVEENYHDAPIVGIAVVNEHG-RFFLRPETALAD  354
            +A +++     V+ ++++    +  E + +NYH  +I+G+A    HG +++   + +L  
Sbjct  302  VAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFA--WGHGEQIYASTDLSLLA  359

Query  355  PQFVAWLGDETKKKSMFDSKRAAVALKWKGIELCGVSFdlllaaylldPAQGVDDVAAAA  414
             +  +      K  + +D KR+ V L   GIEL + S+D  LA YLL   ++ +++++ A
Sbjct  360  TD--SFKQVFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NELSTIA  416

Query  415  KMKQYEAVRPDEAVYGKGAKRAVPDEPVLAEHLVRKAAAIWALERPFLDELRRNEQDRLL  474
            ++    ++  D++VYGKGAKRAVPD  VL EHL RK   +       LD L  +EQ  L 
Sbjct  417  RIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLY  476

Query  475  VELEQPLSSILAEMEFAGVKVDTKRLEQMGEELAEQLRTVEQRIYELAGQEFNINSPKQL  534
             ++E PL+++LA ME+ G+KV+   L++M+E+    + ++ Q IY++AGQEFNINSPKQL
Sbjct  477  QNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQL  536

Query  535  GVILFEKLQLP--VLKKTKTGYSTSADVLEKLAPYHEIVENILHYRQLGKLQSTYIEGLL  592
            G ILFEK+QLP  + KKTKTGYST+ DVLE+LAP   IV +IL+YRQ+ KLQSTY+ GL 
Sbjct  537  GSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQ  596

Query  593  KVVRPDTKKVHTIFNQALTQTGRLSSTEPNLQNIPIRLEEGRKIRQAFVPSESDWLIFAA  652
              + +D K +HT + Q LTQTGRLSS +PNLQNIPIRLE+GR IR+AF PS+ D +++++
Sbjct  597  DYILADGK-IHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSS  655

Query  653  DYSQIELRVLAHIAEDDNLMEAFRRDLDIHTKTAMDIFQVS-EDEVTPNMRRQAKAVNFG  711
            DYSQIELRVLAHI+ D++L+ AF  + DIHT TAM +F +    +VT+N RR+AKAVNFG
Sbjct  656  DYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFG  715

Query  712  IVYGISDYGLAQNLNISRKEAAEFIERYFESFPGVKRYMENIVQEAKQKGYVTTLLHRRR  771
            IVYGISD+GL++NL I+RK++  +I+ YFE +PG+K YMEN+V+EAK+KGYV TL+ RRR
Sbjct  716  IVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRR  775

Query  772  YLPDITSRNFNVRSFAERMAMNTPIQGSAADIIKKAMIDLNARLKEERLQARLLLQVHDE  831
             LPDI SRNFNVRSFAER A+N+PIQGSAADI+K AMI+L+  L+   ++A++LLQVHDE
Sbjct  776  ELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDE  835

Query  832  LILEAPKEEMERLCRLVPEVMEQAVTLRVPLKVDYHYGSTWYDAK  876
            ++LE P++E+  + +LV + ME AV L VPL VD   G +WY+AK
Sbjct  836  IVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

270) GYMC52_2765 in NC_014915


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  700 bits (2646),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 449/885 (51%), Positives = 641/885 (73%), Gaps = 18/885 (2%)

Query  2    KKKLVLIDGSSVAYRAFFAL----PLLHNDKGIHTNAVYGFTMMLNKILAEEEPTHMLVA  57
            K+KL+LIDGSSVA+RAFFAL      + N+ G+HTNA+YGF +ML+ ++    PTH+LVA
Sbjct  4    KNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVA  63

Query  58   FDAGKTTFRHEAFQEYKGGRQQTPPELSEQFPLLRELLRAYRIPAYELENYEADDIIGTL  117
            FDAGKTTFR E + +YK+GR +TP E+ EQF+ +RE+L A  I+ YELE+YEADDIIGTL
Sbjct  64   FDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTL  123

Query  118  AARAEQEG--FEVKVISGDRDLTQLASPHVTVDITKKGITDIEPYTPETVREKYGLTPEQ  175
               AE+    F+V ++SGD+DL QL+  +  V+I+KKG++++E +TP  + EK GLTP+Q
Sbjct  124  DKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQ  183

Query  176  IVDLKGLMGDKSDNIPGVPGIGEKTAVKLLRQFGTVENVLASIDEIKGEKLKETLRQHRE  235
            ++DLK+LMGDKSDNIPGV  IGEKT++KLL++FG++E +   ID +K  K+KE L ++R+
Sbjct  184  FIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRD  243

Query  236  MALLSKKLAAIRRDAPVELSLDDIAYQGEDREKVVALFKELGFQSFLekmespsseeekp  295
             A+LSK LA+I   +P+ ++LDDI Y+G D   +  ++ E++F  +  K   +S   + P
Sbjct  244  QAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQL--KKGLASQMPQEP  301

Query  296  LAKMAFTLADRVTEEMLADKAALVVEVVEENYHDAPIVGIAVVNEHG-RFFLRPETALAD  354
            +A +++     V+ ++++    +  E + +NYH  +I+G+A    HG +++   + +L  
Sbjct  302  VAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFA--WGHGEQIYASTDLSLLA  359

Query  355  PQFVAWLGDETKKKSMFDSKRAAVALKWKGIELCGVSFdlllaaylldPAQGVDDVAAAA  414
             +  +      K  + +D KR+ V L   GIEL + S+D  LA YLL   ++ +++++ A
Sbjct  360  TD--SFKQVFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NELSTIA  416

Query  415  KMKQYEAVRPDEAVYGKGAKRAVPDEPVLAEHLVRKAAAIWALERPFLDELRRNEQDRLL  474
            ++    ++  D++VYGKGAKRAVPD  VL EHL RK   +       LD L  +EQ  L 
Sbjct  417  RIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLY  476

Query  475  VELEQPLSSILAEMEFAGVKVDTKRLEQMGEELAEQLGTVEQRIYELAGQEFNINSPKQL  534
             ++E PL+++LA ME+ G+KV+   L++M+E+    + ++ Q IY++AGQEFNINSPKQL
Sbjct  477  QNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQL  536

Query  535  GVILFEKLQLP--VLKKTKTGYSTSADVLEKLAPYHEIVENILHYRQLGKLQSTYIEGLL  592
            G ILFEK+QLP  + KKTKTGYST+ DVLE+LAP   IV +IL+YRQ+ KLQSTY+ GL 
Sbjct  537  GSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQ  596

Query  593  KVVRPDTKKVHTIFNQALTQTGRLSSTEPNLQNIPIRLEEGRKIRQAFVPSESDWLIFAA  652
              + +D K +HT + Q LTQTGRLSS +PNLQNIPIRLE+GR IR+AF PS+ D +++++
Sbjct  597  DYILADGK-IHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSS  655

Query  653  DYSQIELRVLAHIAEDDNLMEAFRRDLDIHTKTAMDIFQVS-EDEVTPNMRRQAKAVNFG  711
            DYSQIELRVLAHI+ D++L+ AF  + DIHT TAM +F +    +VT+N RR+AKAVNFG
Sbjct  656  DYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFG  715

Query  712  IVYGISDYGLAQNLNISRKEAAEFIERYFESFPGVKRYMENIVQEAKQKGYVTTLLHRRR  771
            IVYGISD+GL++NL I+RK++  +I+ YFE +PG+K YMEN+V+EAK+KGYV TL+ RRR
Sbjct  716  IVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRR  775

Query  772  YLPDITSRNFNVRSFAERMAMNTPIQGSAADIIKKAMIDLNARLKEERLQARLLLQVHDE  831
             LPDI SRNFNVRSFAER A+N+PIQGSAADI+K AMI+L+  L+   ++A++LLQVHDE
Sbjct  776  ELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDE  835

Query  832  LILEAPKEEMERLCRLVPEVMEQAVTLRVPLKVDYHYGSTWYDAK  876
            ++LE P++E+  + +LV + ME AV L VPL VD   G +WY+AK
Sbjct  836  IVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

271) GYMC61_0787 in NC_013411


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  700 bits (2646),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 449/885 (51%), Positives = 641/885 (73%), Gaps = 18/885 (2%)

Query  2    KKKLVLIDGSSVAYRAFFAL----PLLHNDKGIHTNAVYGFTMMLNKILAEEEPTHMLVA  57
            K+KL+LIDGSSVA+RAFFAL      + N+ G+HTNA+YGF +ML+ ++    PTH+LVA
Sbjct  4    KNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVA  63

Query  58   FDAGKTTFRHEAFQEYKGGRQQTPPELSEQFPLLRELLRAYRIPAYELENYEADDIIGTL  117
            FDAGKTTFR E + +YK+GR +TP E+ EQF+ +RE+L A  I+ YELE+YEADDIIGTL
Sbjct  64   FDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTL  123

Query  118  AARAEQEG--FEVKVISGDRDLTQLASPHVTVDITKKGITDIEPYTPETVREKYGLTPEQ  175
               AE+    F+V ++SGD+DL QL+  +  V+I+KKG++++E +TP  + EK GLTP+Q
Sbjct  124  DKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQ  183

Query  176  IVDLKGLMGDKSDNIPGVPGIGEKTAVKLLRQFGTVENVLASIDEIKGEKLKETLRQHRE  235
            ++DLK+LMGDKSDNIPGV  IGEKT++KLL++FG++E +   ID +K  K+KE L ++R+
Sbjct  184  FIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRD  243

Query  236  MALLSKKLAAIRRDAPVELSLDDIAYQGEDREKVVALFKELGFQSFLekmespsseeekp  295
             A+LSK LA+I   +P+ ++LDDI Y+G D   +  ++ E++F  +  K   +S   + P
Sbjct  244  QAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQL--KKGLASQMPQEP  301

Query  296  LAKMAFTLADRVTEEMLADKAALVVEVVEENYHDAPIVGIAVVNEHG-RFFLRPETALAD  354
            +A +++     V+ ++++    +  E + +NYH  +I+G+A    HG +++   + +L  
Sbjct  302  VAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFA--WGHGEQIYASTDLSLLA  359

Query  355  PQFVAWLGDETKKKSMFDSKRAAVALKWKGIELCGVSFdlllaaylldPAQGVDDVAAAA  414
             +  +      K  + +D KR+ V L   GIEL + S+D  LA YLL   ++ +++++ A
Sbjct  360  TD--SFKQVFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NELSTIA  416

Query  415  KMKQYEAVRPDEAVYGKGAKRAVPDEPVLAEHLVRKAAAIWALERPFLDELRRNEQDRLL  474
            ++    ++  D++VYGKGAKRAVPD  VL EHL RK   +       LD L  +EQ  L 
Sbjct  417  RIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLY  476

Query  475  VELEQPLSSILAEMEFAGVKVDTKRLEQMGEELAEQLGTVEQRIYELAGQEFNINSPKQL  534
             ++E PL+++LA ME+ G+KV+   L++M+E+    + ++ Q IY++AGQEFNINSPKQL
Sbjct  477  QNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQL  536

Query  535  GVILFEKLQLP--VLKKTKTGYSTSADVLEKLAPYHEIVENILHYRQLGKLQSTYIEGLL  592
            G ILFEK+QLP  + KKTKTGYST+ DVLE+LAP   IV +IL+YRQ+ KLQSTY+ GL 
Sbjct  537  GSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQ  596

Query  593  KVVRPDTKKVHTIFNQALTQTGRLSSTEPNLQNIPIRLEEGRKIRQAFVPSESDWLIFAA  652
              + +D K +HT + Q LTQTGRLSS +PNLQNIPIRLE+GR IR+AF PS+ D +++++
Sbjct  597  DYILADGK-IHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSS  655

Query  653  DYSQIELRVLAHIAEDDNLMEAFRRDLDIHTKTAMDIFQVS-EDEVTPNMRRQAKAVNFG  711
            DYSQIELRVLAHI+ D++L+ AF  + DIHT TAM +F +    +VT+N RR+AKAVNFG
Sbjct  656  DYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFG  715

Query  712  IVYGISDYGLAQNLNISRKEAAEFIERYFESFPGVKRYMENIVQEAKQKGYVTTLLHRRR  771
            IVYGISD+GL++NL I+RK++  +I+ YFE +PG+K YMEN+V+EAK+KGYV TL+ RRR
Sbjct  716  IVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRR  775

Query  772  YLPDITSRNFNVRSFAERMAMNTPIQGSAADIIKKAMIDLNARLKEERLQARLLLQVHDE  831
             LPDI SRNFNVRSFAER A+N+PIQGSAADI+K AMI+L+  L+   ++A++LLQVHDE
Sbjct  776  ELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDE  835

Query  832  LILEAPKEEMERLCRLVPEVMEQAVTLRVPLKVDYHYGSTWYDAK  876
            ++LE P++E+  + +LV + ME AV L VPL VD   G +WY+AK
Sbjct  836  IVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

272) polA in NC_016047


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  700 bits (2648),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 438/890 (50%), Positives = 647/890 (73%), Gaps = 20/890 (2%)

Query  1    MTERKKLVLVDGNSLAYRAFFAL----PLLSNDKGIHTNAVYGFAMILMKMLEDEKPTHM  56
            M +++KL+L+DG+S+A+RAFFAL      + N+ G+HTNA+YGF ++L  M+   +PTH+
Sbjct  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60

Query  57   LVAFDAGKTTFRHGTFKEYKGGRQKTPPELSEQMPFIRELLDAYQISRYELEQYEADDII  116
            LVAFDAGKTTFR   + +YK+GR KTP E+ EQ ++IRE+L A  I+ YELE+YEADDII
Sbjct  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120

Query  117  GTLAKSAEKDG--FEVKIFSGDKDLTQLATDKTTVAITRKGITDVEFYTPEHVKEKYGLT  174
            GTL K AE+    F+V I SGDKDL QL+ ++T V I++KG+++ E +TP  + EK GLT
Sbjct  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180

Query  175  PEQIIDMKGLMGDSSDNIPGVPGVGEKTAIKLLKQFDSVEKLLESIDEVSGkklkeklee  234
            P+Q+ID+K+LMGD SDNIPGV  +GEKT++KLL +F+S+E + E ID     K+KE+L +
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  235  fkDQALMSKELATIMTDAPIEVSVSGLEYQGFNREQVIAIFKDLGFNTLLERLGEDSEEA  294
             +DQA++SK LATI T +PI +++ ++ Y+G +   +  ++ +++F  L   L+ +    
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQM---  297

Query  295  EQDQALEEIKVETVTDVTSGILVSPSAFVVEQIGDNYHEEPLLGFSIINETGSYFIPKDI  354
              ++++  I  + VT+V+++++ +   F  E + DNYH E+++GF+  +    Y  + D+
Sbjct  298  -PQEPVAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIY-ASTDL  355

Query  355  AV-ESKVFKEWAENDEQKKWLFDSKRAVVALRWQGIELKGAEFDTLLAAYIINPGNSYDD  413
            ++  +  FK+  ++       +D KR+ V L   GIEL ++ +D+ LA Y+++  +  ++
Sbjct  356  SLLATDSFKQVFQKPIAT---YDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NE  411

Query  414  VASVAKDYGLHIVSSDESVYGKGAKRAVPSEDVLSEHLVRKALAIQSLREKLVQELENND  473
            ++++A+ +    +  D++VYGKGAKRAVP  DVL EHL RK   +   + ++++ L  ++
Sbjct  412  LSTIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHE  471

Query  474  QLELFEELEMPLALILGEMESTGVKVDVDRLKRMGEELGAKLKEYEEKIHEIAGEPFNIN  533
            QL+L++++E+PLA +L+ ME  G+KV+   L+ M+E+    +    + I ++AG+ FNIN
Sbjct  472  QLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNIN  531

Query  534  SPKQLGVILFEKIGLP--VVKKTKTGYSTSADVLEKLADKHEIVDYILQYRQIGKLQSTY  591
            SPKQLG ILFEK+ LP  + KKTKTGYST+ DVLE+LA    IV  IL+YRQI KLQSTY
Sbjct  532  SPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTY  591

Query  592  VEGLLKVTRPDSHKVHTRFNQALTQTGRLSSTDPNLQNIPIRLEEGRKIRQAFVPSEKDW  651
            V GL     +D+ K+HTR+ Q LTQTGRLSS DPNLQNIPIRLE+GR IR+AF PS+ D 
Sbjct  592  VIGLQDYILADG-KIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDA  650

Query  652  LIFAADYSQIELRVLAHISKDQNLIEAFTNDMDIHTKTAMDVFHVA-EDEVTSAMRRQAK  710
            +++++DYSQIELRVLAHIS D++LI AF ++ DIHT TAM VF +    +VT+  RR+AK
Sbjct  651  VLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAK  710

Query  711  AVNFGIVYGISDYGLSQNLGITRKEAGAFIERYLESFQGVKAYMEDSVQDAKQKGYVTTL  770
            AVNFGIVYGISD+GLS+NLGITRK++ ++I+ Y+E + G+KAYME+ V++AK+KGYV TL
Sbjct  711  AVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETL  770

Query  771  MHRRRYIPELTSRNFNIRSFAERTAMNTPIQGSAADIIKKAMIDMAAKLKEKQLKARLLL  830
              RRR +P++ SRNFN+RSFAERTA+N+PIQGSAADI+K AMI++   L+   ++A++LL
Sbjct  771  FKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLL  830

Query  831  QVHDELIFEAPQEEIEILEKLVPEVMEHALALDVPLKVDFASGPSWYDAK  880
            QVHDE+++E P++E+  + KLV + ME A+ L VPL VD ++G SWY+AK
Sbjct  831  QVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

273) GC56T3_0763 in NC_014206


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  699 bits (2643),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 449/885 (51%), Positives = 641/885 (73%), Gaps = 18/885 (2%)

Query  2    KKKLVLIDGSSVAYRAFFAL----PLLHNDKGIHTNAVYGFTMMLNKILAEEEPTHMLVA  57
            K+KL+LIDGSSVA+RAFFAL      + N+ G+HTNA+YGF +ML+ ++    PTH+LVA
Sbjct  4    KNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVA  63

Query  58   FDAGKTTFRHEAFQEYKGGRQQTPPELSEQFPLLRELLRAYRIPAYELENYEADDIIGTL  117
            FDAGKTTFR E + +YK+GR +TP E+ EQF+ +RE+L A  I+ YELE+YEADDIIGTL
Sbjct  64   FDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTL  123

Query  118  AARAEQEG--FEVKVISGDRDLTQLASPHVTVDITKKGITDIEPYTPETVREKYGLTPEQ  175
               AE+    F+V ++SGD+DL QL+  +  V+I+KKG++++E +TP  + EK GLTP+Q
Sbjct  124  DKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQ  183

Query  176  IVDLKGLMGDKSDNIPGVPGIGEKTAVKLLRQFGTVENVLASIDEIKGEKLKETLRQHRE  235
            ++DLK+LMGDKSDNIPGV  IGEKT++KLL++FG++E +   ID +K  K+KE L ++R+
Sbjct  184  FIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRD  243

Query  236  MALLSKKLAAIRRDAPVELSLDDIAYQGEDREKVVALFKELGFQSFLekmespsseeekp  295
             A+LSK LA+I   +P+ ++LDDI Y+G D   +  ++ E++F  +  K   +S   + P
Sbjct  244  QAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQL--KKGLASQMPQEP  301

Query  296  LAKMAFTLADRVTEEMLADKAALVVEVVEENYHDAPIVGIAVVNEHG-RFFLRPETALAD  354
            +A +++     V+ ++++    +  E + +NYH  +I+G+A    HG +++   + +L  
Sbjct  302  VAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFA--WGHGEQIYASTDLSLLA  359

Query  355  PQFVAWLGDETKKKSMFDSKRAAVALKWKGIELCGVSFdlllaaylldPAQGVDDVAAAA  414
             +  +      K  + +D KR+ V L   GIEL + S+D  LA YLL   ++ +++++ A
Sbjct  360  TD--SFKQVFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NELSTIA  416

Query  415  KMKQYEAVRPDEAVYGKGAKRAVPDEPVLAEHLVRKAAAIWALERPFLDELRRNEQDRLL  474
            ++    ++  D++VYGKGAKRAVPD  VL EHL RK   +       LD L  +EQ  L 
Sbjct  417  RIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLY  476

Query  475  VELEQPLSSILAEMEFAGVKVDTKRLEQMGEELAEQLRTVEQRIYELAGQEFNINSPKQL  534
             ++E PL+++LA ME+ G+KV+   L++M+E+    + ++ Q IY++AGQEFNINSPKQL
Sbjct  477  QNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQL  536

Query  535  GVILFEKLQLP--VLKKTKTGYSTSADVLEKLAPYHEIVENILHYRQLGKLQSTYIEGLL  592
            G ILFEK+QLP  + KKTKTGYST+ DVLE+LAP   IV +IL+YRQ+ KLQSTY+ GL 
Sbjct  537  GSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQ  596

Query  593  KVVRPDTKKVHTIFNQALTQTGRLSSTEPNLQNIPIRLEEGRKIRQAFVPSESDWLIFAA  652
              + +D K +HT + Q LTQTGRLSS +PNLQNIPIRLE+GR IR+AF PS+ D +++++
Sbjct  597  DYILADGK-IHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSS  655

Query  653  DYSQIELRVLAHIAEDDNLMEAFRRDLDIHTKTAMDIFQVS-EDEVTPNMRRQAKAVNFG  711
            DYSQIELRVLAHI+ D++L+ AF  + DIHT TAM +F +    +VT+N RR+AKAVNFG
Sbjct  656  DYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFG  715

Query  712  IVYGISDYGLAQNLNISRKEAAEFIERYFESFPGVKRYMENIVQEAKQKGYVTTLLHRRR  771
            IVYGISD+GL++NL I+RK++  +I+ YFE +PG+K YMEN+V+EAK+KGYV TL+ RRR
Sbjct  716  IVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRR  775

Query  772  YLPDITSRNFNVRSFAERMAMNTPIQGSAADIIKKAMIDLNARLKEERLQARLLLQVHDE  831
             LPDI SRNFNVRSFAER A+N+PIQGSAADI+K AMI+L+  L+   ++A++LLQVHDE
Sbjct  776  ELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDE  835

Query  832  LILEAPKEEMERLCRLVPEVMEQAVTLRVPLKVDYHYGSTWYDAK  876
            ++LE P++E+  + +LV + ME AV L VPL VD   G +WY+AK
Sbjct  836  IVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

274) polA3 in NC_014551


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  699 bits (2643),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 442/888 (50%), Positives = 640/888 (73%), Gaps = 17/888 (1%)

Query  1    MTERKKLVLVDGNSLAYRAFFAL----PLLSNEKGIHTNAVYGFAMILMKMLEDEKPTHM  56
            M +++KL+L+DG+S+A+RAFFAL      + N+ G+HTNA+YGF ++L  M+   +PTH+
Sbjct  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60

Query  57   LVAFDAGKTTFRHSTFKEYKGGRQKTPPELSEQMPFIRELLDAYNISRYELPEYEADDII  116
            LVAFDAGKTTFR   + +YK+GR KTP E+ EQ ++IRE+L A  I+ YEL +YEADDII
Sbjct  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120

Query  117  GTLAVSAEKDG--FEVKVFSGDKDLTQLATGKTTVAITRKGITDVEDYTPEHVEEKYGLT  174
            GTL   AE+    F+V + SGDKDL QL+  +T V I++KG+++ E++TP  + EK GLT
Sbjct  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180

Query  175  PLQIIDMKGLMGDSSDNIPGVPGVGEKTAIKLLKQFHSVEKLLDSIDEVSgkklkeklge  234
            P Q+ID+K+LMGD SDNIPGV  +GEKT++KLL +F S+E + + ID     K+KE+L +
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  235  ykeQALMSKELATIMTNAPIEVKLEDLDYQGFDREQVVAIFKDLGFNTLLERLGEESGET  294
             ++QA++SK LATI T +PI + L+D+ Y+G D   +  ++ +++F  L   L+   ++ 
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLA---SQM  297

Query  295  AEEDFEDIDVETVEEITEDMLVSPSALVVEQIGDNYHEEPILGFSIVNETGLYYIPKETA  354
            ++E    I  + V +++ D++ +   +  E + DNYH E+I+GF+  +   +Y     + 
Sbjct  298  PQEPVAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSL  357

Query  355  IQSEAFKSWAEDESKKKWVFDSKRSVVALRWQGIELKGTEFDALLAAYIINPGNSYDDVA  414
            + +++FK   +   K    +D KRS V L   GIEL +  +DA LA Y+++  +  ++++
Sbjct  358  LATDSFKQVFQ---KPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NELS  413

Query  415  SVAKEYGLNIVSKDEAVYGKGAKHAVPAEKELADHLARKAAAVNSLRDKLLHALKENNQL  474
            ++A+ +    +  D++VYGKGAK+AVP    L +HLARK   +   + ++L+ L  ++QL
Sbjct  414  TIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQL  473

Query  475  ELYEDLELPLALILGEMESMGVKVDVERLKRMGEELRAKLKEYEEKIHDIAGEPFNINSP  534
            +LY+++ELPLA +L+ ME  G+KV+   L+ M+E+ +  +    + I D+AG+ FNINSP
Sbjct  474  DLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSP  533

Query  535  KQLGVILFDKLGLP--VVKKTKTGYSTSADVLEKLADKHDIVAYILQYRQIGKLQSTYIE  592
            KQLG ILF+K+ LP  + KKTKTGYST+ DVLE+LA    IVA IL+YRQI KLQSTY+ 
Sbjct  534  KQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVI  593

Query  593  GLLKVTRKDSHKVHTRFNQALTQTGRLSSTDPNLQNIPIRLEEGRKIRQAFVPSEPDWLI  652
            GL      D+ K+HTR+ Q LTQTGRLSS DPNLQNIPIRLE+GR IR+AF PS+ D ++
Sbjct  594  GLQDYILADG-KIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVL  652

Query  653  FAADYSQIELRVLAHISKDENLIEAFTNDMDIHTKTAMDVFHVS-EDEVTQAMRRQAKAV  711
            +++DYSQIELRVLAHIS DE+LI AF ++ DIHT TAM VF +    +VT   RR+AKAV
Sbjct  653  LSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAV  712

Query  712  NFGIVYGISDYGLSQNLGITRKEAGAFIDRYLESFPGVKAYMEESVQEAKQKGYVTTLMQ  771
            NFGIVYGISD+GLS+NLGITRK++ ++ID Y+E +PG+KAYME+ V+EAK+KGYV TL +
Sbjct  713  NFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFK  772

Query  772  RRRYIPELTSRNFNLRSFAERTAMNTPIQGSAADIIKKAMIDMAAELKEKNLKARLLLQV  831
            RRR +P++ SRNFN+RSFAERTA+N+PIQGSAADI+K AMI++   L+   ++A++LLQV
Sbjct  773  RRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQV  832

Query  832  HDELIFEAPKEEIKILEKLVPEVMEHALDLDVPLKADYASGPSWYDAK  879
            HDE+++E P++E+  + KLV + ME A+DL VPL  D ++G SWY+AK
Sbjct  833  HDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

275) polA in NC_017190


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  699 bits (2643),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 442/888 (50%), Positives = 640/888 (73%), Gaps = 17/888 (1%)

Query  1    MTERKKLVLVDGNSLAYRAFFAL----PLLSNEKGIHTNAVYGFAMILMKMLEDEKPTHM  56
            M +++KL+L+DG+S+A+RAFFAL      + N+ G+HTNA+YGF ++L  M+   +PTH+
Sbjct  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60

Query  57   LVAFDAGKTTFRHSTFKEYKGGRQKTPPELSEQMPFIRELLDAYNISRYELPEYEADDII  116
            LVAFDAGKTTFR   + +YK+GR KTP E+ EQ ++IRE+L A  I+ YEL +YEADDII
Sbjct  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120

Query  117  GTLAVSAEKDG--FEVKVFSGDKDLTQLATGKTTVAITRKGITDVEDYTPEHVEEKYGLT  174
            GTL   AE+    F+V + SGDKDL QL+  +T V I++KG+++ E++TP  + EK GLT
Sbjct  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180

Query  175  PLQIIDMKGLMGDSSDNIPGVPGVGEKTAIKLLKQFHSVEKLLDSIDEVSgkklkeklge  234
            P Q+ID+K+LMGD SDNIPGV  +GEKT++KLL +F S+E + + ID     K+KE+L +
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  235  ykeQALMSKELATIMTNAPIEVKLEDLDYQGFDREQVVAIFKDLGFNTLLERLGEESGET  294
             ++QA++SK LATI T +PI + L+D+ Y+G D   +  ++ +++F  L   L+   ++ 
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLA---SQM  297

Query  295  AEEDFEDIDVETVEEITEDMLVSPSALVVEQIGDNYHEEPILGFSIVNETGLYYIPKETA  354
            ++E    I  + V +++ D++ +   +  E + DNYH E+I+GF+  +   +Y     + 
Sbjct  298  PQEPVAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSL  357

Query  355  IQSEAFKSWAEDESKKKWVFDSKRSVVALRWQGIELKGTEFDALLAAYIINPGNSYDDVA  414
            + +++FK   +   K    +D KRS V L   GIEL +  +DA LA Y+++  +  ++++
Sbjct  358  LATDSFKQVFQ---KPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NELS  413

Query  415  SVAKEYGLNIVSKDEAVYGKGAKHAVPAEKELADHLARKAAAVNSLRDKLLHALKENNQL  474
            ++A+ +    +  D++VYGKGAK+AVP    L +HLARK   +   + ++L+ L  ++QL
Sbjct  414  TIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQL  473

Query  475  ELYEDLELPLALILGEMESMGVKVDVERLKRMGEELRAKLKEYEEKIHDIAGEPFNINSP  534
            +LY+++ELPLA +L+ ME  G+KV+   L+ M+E+ +  +    + I D+AG+ FNINSP
Sbjct  474  DLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSP  533

Query  535  KQLGVILFDKLGLP--VVKKTKTGYSTSADVLEKLADKHDIVAYILQYRQIGKLQSTYIE  592
            KQLG ILF+K+ LP  + KKTKTGYST+ DVLE+LA    IVA IL+YRQI KLQSTY+ 
Sbjct  534  KQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVI  593

Query  593  GLLKVTRKDSHKVHTRFNQALTQTGRLSSTDPNLQNIPIRLEEGRKIRQAFVPSEPDWLI  652
            GL      D+ K+HTR+ Q LTQTGRLSS DPNLQNIPIRLE+GR IR+AF PS+ D ++
Sbjct  594  GLQDYILADG-KIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVL  652

Query  653  FAADYSQIELRVLAHISKDENLIEAFTNDMDIHTKTAMDVFHVS-EDEVTQAMRRQAKAV  711
            +++DYSQIELRVLAHIS DE+LI AF ++ DIHT TAM VF +    +VT   RR+AKAV
Sbjct  653  LSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAV  712

Query  712  NFGIVYGISDYGLSQNLGITRKEAGAFIDRYLESFPGVKAYMEESVQEAKQKGYVTTLMQ  771
            NFGIVYGISD+GLS+NLGITRK++ ++ID Y+E +PG+KAYME+ V+EAK+KGYV TL +
Sbjct  713  NFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFK  772

Query  772  RRRYIPELTSRNFNLRSFAERTAMNTPIQGSAADIIKKAMIDMAAELKEKNLKARLLLQV  831
            RRR +P++ SRNFN+RSFAERTA+N+PIQGSAADI+K AMI++   L+   ++A++LLQV
Sbjct  773  RRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQV  832

Query  832  HDELIFEAPKEEIKILEKLVPEVMEHALDLDVPLKADYASGPSWYDAK  879
            HDE+++E P++E+  + KLV + ME A+DL VPL  D ++G SWY+AK
Sbjct  833  HDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

276) polA in NC_017188


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  699 bits (2643),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 442/888 (50%), Positives = 640/888 (73%), Gaps = 17/888 (1%)

Query  1    MTERKKLVLVDGNSLAYRAFFAL----PLLSNEKGIHTNAVYGFAMILMKMLEDEKPTHM  56
            M +++KL+L+DG+S+A+RAFFAL      + N+ G+HTNA+YGF ++L  M+   +PTH+
Sbjct  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60

Query  57   LVAFDAGKTTFRHSTFKEYKGGRQKTPPELSEQMPFIRELLDAYNISRYELPEYEADDII  116
            LVAFDAGKTTFR   + +YK+GR KTP E+ EQ ++IRE+L A  I+ YEL +YEADDII
Sbjct  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120

Query  117  GTLAVSAEKDG--FEVKVFSGDKDLTQLATGKTTVAITRKGITDVEDYTPEHVEEKYGLT  174
            GTL   AE+    F+V + SGDKDL QL+  +T V I++KG+++ E++TP  + EK GLT
Sbjct  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180

Query  175  PLQIIDMKGLMGDSSDNIPGVPGVGEKTAIKLLKQFHSVEKLLDSIDEVSgkklkeklge  234
            P Q+ID+K+LMGD SDNIPGV  +GEKT++KLL +F S+E + + ID     K+KE+L +
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  235  ykeQALMSKELATIMTNAPIEVKLEDLDYQGFDREQVVAIFKDLGFNTLLERLGEESGET  294
             ++QA++SK LATI T +PI + L+D+ Y+G D   +  ++ +++F  L   L+   ++ 
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLA---SQM  297

Query  295  AEEDFEDIDVETVEEITEDMLVSPSALVVEQIGDNYHEEPILGFSIVNETGLYYIPKETA  354
            ++E    I  + V +++ D++ +   +  E + DNYH E+I+GF+  +   +Y     + 
Sbjct  298  PQEPVAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSL  357

Query  355  IQSEAFKSWAEDESKKKWVFDSKRSVVALRWQGIELKGTEFDALLAAYIINPGNSYDDVA  414
            + +++FK   +   K    +D KRS V L   GIEL +  +DA LA Y+++  +  ++++
Sbjct  358  LATDSFKQVFQ---KPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NELS  413

Query  415  SVAKEYGLNIVSKDEAVYGKGAKHAVPAEKELADHLARKAAAVNSLRDKLLHALKENNQL  474
            ++A+ +    +  D++VYGKGAK+AVP    L +HLARK   +   + ++L+ L  ++QL
Sbjct  414  TIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQL  473

Query  475  ELYEDLELPLALILGEMESMGVKVDVERLKRMGEELRAKLKEYEEKIHDIAGEPFNINSP  534
            +LY+++ELPLA +L+ ME  G+KV+   L+ M+E+ +  +    + I D+AG+ FNINSP
Sbjct  474  DLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSP  533

Query  535  KQLGVILFDKLGLP--VVKKTKTGYSTSADVLEKLADKHDIVAYILQYRQIGKLQSTYIE  592
            KQLG ILF+K+ LP  + KKTKTGYST+ DVLE+LA    IVA IL+YRQI KLQSTY+ 
Sbjct  534  KQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVI  593

Query  593  GLLKVTRKDSHKVHTRFNQALTQTGRLSSTDPNLQNIPIRLEEGRKIRQAFVPSEPDWLI  652
            GL      D+ K+HTR+ Q LTQTGRLSS DPNLQNIPIRLE+GR IR+AF PS+ D ++
Sbjct  594  GLQDYILADG-KIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVL  652

Query  653  FAADYSQIELRVLAHISKDENLIEAFTNDMDIHTKTAMDVFHVS-EDEVTQAMRRQAKAV  711
            +++DYSQIELRVLAHIS DE+LI AF ++ DIHT TAM VF +    +VT   RR+AKAV
Sbjct  653  LSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAV  712

Query  712  NFGIVYGISDYGLSQNLGITRKEAGAFIDRYLESFPGVKAYMEESVQEAKQKGYVTTLMQ  771
            NFGIVYGISD+GLS+NLGITRK++ ++ID Y+E +PG+KAYME+ V+EAK+KGYV TL +
Sbjct  713  NFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFK  772

Query  772  RRRYIPELTSRNFNLRSFAERTAMNTPIQGSAADIIKKAMIDMAAELKEKNLKARLLLQV  831
            RRR +P++ SRNFN+RSFAERTA+N+PIQGSAADI+K AMI++   L+   ++A++LLQV
Sbjct  773  RRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQV  832

Query  832  HDELIFEAPKEEIKILEKLVPEVMEHALDLDVPLKADYASGPSWYDAK  879
            HDE+++E P++E+  + KLV + ME A+DL VPL  D ++G SWY+AK
Sbjct  833  HDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

277) BAXH7_02925 in NC_017191


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  699 bits (2643),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 442/888 (50%), Positives = 640/888 (73%), Gaps = 17/888 (1%)

Query  1    MTERKKLVLVDGNSLAYRAFFAL----PLLSNEKGIHTNAVYGFAMILMKMLEDEKPTHM  56
            M +++KL+L+DG+S+A+RAFFAL      + N+ G+HTNA+YGF ++L  M+   +PTH+
Sbjct  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60

Query  57   LVAFDAGKTTFRHSTFKEYKGGRQKTPPELSEQMPFIRELLDAYNISRYELPEYEADDII  116
            LVAFDAGKTTFR   + +YK+GR KTP E+ EQ ++IRE+L A  I+ YEL +YEADDII
Sbjct  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120

Query  117  GTLAVSAEKDG--FEVKVFSGDKDLTQLATGKTTVAITRKGITDVEDYTPEHVEEKYGLT  174
            GTL   AE+    F+V + SGDKDL QL+  +T V I++KG+++ E++TP  + EK GLT
Sbjct  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180

Query  175  PLQIIDMKGLMGDSSDNIPGVPGVGEKTAIKLLKQFHSVEKLLDSIDEVSgkklkeklge  234
            P Q+ID+K+LMGD SDNIPGV  +GEKT++KLL +F S+E + + ID     K+KE+L +
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  235  ykeQALMSKELATIMTNAPIEVKLEDLDYQGFDREQVVAIFKDLGFNTLLERLGEESGET  294
             ++QA++SK LATI T +PI + L+D+ Y+G D   +  ++ +++F  L   L+   ++ 
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLA---SQM  297

Query  295  AEEDFEDIDVETVEEITEDMLVSPSALVVEQIGDNYHEEPILGFSIVNETGLYYIPKETA  354
            ++E    I  + V +++ D++ +   +  E + DNYH E+I+GF+  +   +Y     + 
Sbjct  298  PQEPVAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSL  357

Query  355  IQSEAFKSWAEDESKKKWVFDSKRSVVALRWQGIELKGTEFDALLAAYIINPGNSYDDVA  414
            + +++FK   +   K    +D KRS V L   GIEL +  +DA LA Y+++  +  ++++
Sbjct  358  LATDSFKQVFQ---KPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NELS  413

Query  415  SVAKEYGLNIVSKDEAVYGKGAKHAVPAEKELADHLARKAAAVNSLRDKLLHALKENNQL  474
            ++A+ +    +  D++VYGKGAK+AVP    L +HLARK   +   + ++L+ L  ++QL
Sbjct  414  TIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQL  473

Query  475  ELYEDLELPLALILGEMESMGVKVDVERLKRMGEELRAKLKEYEEKIHDIAGEPFNINSP  534
            +LY+++ELPLA +L+ ME  G+KV+   L+ M+E+ +  +    + I D+AG+ FNINSP
Sbjct  474  DLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSP  533

Query  535  KQLGVILFDKLGLP--VVKKTKTGYSTSADVLEKLADKHDIVAYILQYRQIGKLQSTYIE  592
            KQLG ILF+K+ LP  + KKTKTGYST+ DVLE+LA    IVA IL+YRQI KLQSTY+ 
Sbjct  534  KQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVI  593

Query  593  GLLKVTRKDSHKVHTRFNQALTQTGRLSSTDPNLQNIPIRLEEGRKIRQAFVPSEPDWLI  652
            GL      D+ K+HTR+ Q LTQTGRLSS DPNLQNIPIRLE+GR IR+AF PS+ D ++
Sbjct  594  GLQDYILADG-KIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVL  652

Query  653  FAADYSQIELRVLAHISKDENLIEAFTNDMDIHTKTAMDVFHVS-EDEVTQAMRRQAKAV  711
            +++DYSQIELRVLAHIS DE+LI AF ++ DIHT TAM VF +    +VT   RR+AKAV
Sbjct  653  LSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAV  712

Query  712  NFGIVYGISDYGLSQNLGITRKEAGAFIDRYLESFPGVKAYMEESVQEAKQKGYVTTLMQ  771
            NFGIVYGISD+GLS+NLGITRK++ ++ID Y+E +PG+KAYME+ V+EAK+KGYV TL +
Sbjct  713  NFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFK  772

Query  772  RRRYIPELTSRNFNLRSFAERTAMNTPIQGSAADIIKKAMIDMAAELKEKNLKARLLLQV  831
            RRR +P++ SRNFN+RSFAERTA+N+PIQGSAADI+K AMI++   L+   ++A++LLQV
Sbjct  773  RRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQV  832

Query  832  HDELIFEAPKEEIKILEKLVPEVMEHALDLDVPLKADYASGPSWYDAK  879
            HDE+++E P++E+  + KLV + ME A+DL VPL  D ++G SWY+AK
Sbjct  833  HDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

278) BCO26_1960 in NC_015634


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  698 bits (2639),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 457/883 (52%), Positives = 645/883 (74%), Gaps = 16/883 (1%)

Query  15   KKLILIDGNSIAYRAFFAL----PLLNNDKGIHTNAVYGFTMMLTKILEEEKPTHILVAF  70
            +KL+LIDG+S+A+RAFFAL      ++N+ G+HTNA+YGF +ML  ++   +PTH+LVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  71   DAGKTTFRHETYSEYKGTRQKTPPELSEQFPLIRELLDAHGIERYELENYEADDIIGTLS  130
            DAGKTTFR E Y++YK+ R KTP E+ EQF+ IRE+L A GI  YELE+YEADDIIGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  131  KKAE--EEGFTVKVISGDKDMTQLVSPKTTVMITRKGITDMEAYTPAHVEEKYGLKPHQI  188
            K AE  E  F V ++SGDKD+ QL   +T V I++KG+++ E +TPA + EK GL P+Q+
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  189  IDMKGLMGDSSDNIPGVPGIGEKTAIKLLKQFPTVEELLSHIGEVSGKKLQEKLEAHKEQ  248
            ID+K+LMGD SDNIPGV  IGEKT++KLL +F ++E +  HI+     K++E+L  +++Q
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRDQ  244

Query  249  ALMSKELATIHRDIPLSISIEQAAYRHADPEKLRHLYQELGFKSMLEKMGGGARTEEKPA  308
            A++SK LATI+   P++I++++  Y  +D   L ++Y+E++F  +  K G +++  + P 
Sbjct  245  AFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQL--KKGLASQMPQEP-  301

Query  309  LEAISFSIAEDITDNLFADVSSFYVEILDENYHTGEIIGFGLKNEKGLFFLRAEDALASE  368
            +  IS+    +++ +LF+    FY E L +NYH   IIGF+  +   ++       LA++
Sbjct  302  VAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLATD  361

Query  369  AFKKWVEDESKIKHVYDAKRSIVALRRYGMELRGTGFDLLLVSYLLNPSDTVEDFASVAK  428
            +FK+  +   K    YD KRS V L + G+EL + ++D  L +YLL+  +  ++++++A+
Sbjct  362  SFKQVFQ---KPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NELSTIAR  417

Query  429  THDYGNVETDEAVYGKGAKRKLPGEKRYAEHISRKAEAIDALCEPCTKALKDNGQlelfe  488
                 ++E D++VYGKGAKR +P+     EH++RK   +          L  + QL+L++
Sbjct  418  IFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQ  477

Query  489  qlelplslilADMEYIGVKVDTDRLKEMGEEFKLRLHEIEQRIYSMAGTEFNINSPKQLG  548
            ++ELPL+ +LA ME  G+KV+   L++M+E+ K+ ++ + Q IY MAG EFNINSPKQLG
Sbjct  478  NIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLG  537

Query  549  AILFEKMGLPV--IKKTKTGYSTSADVLEKLEPAHEIVREILHYRQLGKLQSTYIEGLLK  606
            +ILFEKM LP+   KKTKTGYST+ DVLE+L P   IV  IL+YRQ+ KLQSTY+ GL  
Sbjct  538  SILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQD  597

Query  607  VVHRDGKVHTRFNQALTQTGRLSSTDPNLQNIPIRMEEGRKIRQAFVPSEEGWLIFSSDY  666
             +  DGK+HTR+ Q LTQTGRLSS DPNLQNIPIR+E+GR IR+AF PS+E+ +++SSDY
Sbjct  598  YILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDY  657

Query  667  SQVELRVLAHISGDEKLIEAFREGMDIHTKTAMEVFHV-KAEEVTPEMRRQAKAVNFGIV  725
            SQ+ELRVLAHISGDE LI AF EG DIHT TAM VF + KA +VT++ RR+AKAVNFGIV
Sbjct  658  SQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIV  717

Query  726  YGISDYGLSQNLGITRKEAGEFIKRYFASYPRVKEYMDETVREAKQKGYVSTLLKRRRYL  785
            YGISD+GLS+NLGITRK++  +I  YF  YP +K YM++ VREAK+KGYV TL+KRRR L
Sbjct  718  YGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRREL  777

Query  786  PEISSRNFNLRSFAERTAMNTPIQGSAADIIKKAMIDMakrlkkeklrarlllQVHDeli  845
            P+I+SRNFN+RSFAERTA+N+PIQGSAADI+K AMI++ K L+   +RA++LLQVHDE++
Sbjct  778  PDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIV  837

Query  846  feapeeeieVLKEIVPEVMEHAVDLAAPLKVDSAYGPTWFDAK  888
            +E P++E+  +K +V + ME AVDLA PL VD + G +W++AK
Sbjct  838  LEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

279) polA in NC_022075


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  698 bits (2639),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 444/891 (50%), Positives = 643/891 (73%), Gaps = 23/891 (2%)

Query  1    MTERKKLVLVDGNSLAYRAFFAL----PLLSNEKGIHTNAVYGFAMILMKMLEDEKPTHM  56
            M +++KL+L+DG+S+A+RAFFAL      + N+ G+HTNA+YGF ++L  M+   +PTH+
Sbjct  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60

Query  57   LVAFDAGKTTFRHSTFKEYKGGRQKTPPELSEQMPFIRELLDAYNISRYELPEYEADDII  116
            LVAFDAGKTTFR   + +YK+GR KTP E+ EQ ++IRE+L A  I+ YEL +YEADDII
Sbjct  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120

Query  117  GTLAVSAEKEG--FEVKVVSGDKDLTQLATGKTTVAITRKGITDVEDYTPEHVQEKYGLT  174
            GTL   AE+    F+V +VSGDKDL QL+  +T V I++KG+++ E++TP  + EK GLT
Sbjct  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180

Query  175  PLQIIDMKGLMGDSSDNIPGVPGVGEKTAIKLLKQFHSVEKLLDSIDEVSGkklkeklee  234
            P Q+ID+K+LMGD SDNIPGV  +GEKT++KLL +F S+E + + ID     K+KE+L +
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  235  ykeQALMSKELATIMTNAPIEVKPEDLGYQGFDREQVVAIFKDLGFNTLLERLGEESGET  294
             ++QA++SK LATI T +PI +  +D+ Y+G D   +  ++ +++F  L   L+   ++ 
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLA---SQM  297

Query  295  AEENFEDINVETAEEITEDMLVSPSALVVEQIGDNYHEEPILGFSIVNETGLYYIPKEIA  354
            ++E    I+ +   +++ D++ +   +  E + DNYH E+I+GF+  +   +Y  + +++
Sbjct  298  PQEPVAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIY-ASTDLS  356

Query  355  I-QSEAFKSWAEDESMKKWV--FDSKRSVVALRWQGIELKGTEFDALLAAYIINPGNSYD  411
            +  +++FK     +  +K +  +D KRS V L   GIEL +  +DA LA Y+++  +  +
Sbjct  357  LLATDSFK-----QVFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-N  410

Query  412  DVASVAKEYGLNIVSKDEAVYGKGAKRAVPAEKELADHLARKASAVNSLRDKLLDALEEN  471
            +++++A+ +    +  D++VYGKGAKRAVP    L +HLARK   +   + ++LD L  +
Sbjct  411  ELSTIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAH  470

Query  472  NQLELYEDLELPLALILGEMESMGVKVDVERLKRMGeelkaklkeyeekIHDIAGEPFNI  531
            +QL+LY+++ELPLA +L+ ME  G+KV+   L+ M+E+ K  +    + I D+AG+ FNI
Sbjct  471  EQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNI  530

Query  532  NSPKQLGVILFEKLGLP--PVKKTKTGYSTSADVLEKLADKHDIVAHILQYRQIGKLQST  589
            NSPKQLG ILFEK+ LP    KKTKTGYST+ DVLE+LA    IVA IL+YRQI KLQST
Sbjct  531  NSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQST  590

Query  590  YIEGLLKVTRKDSHKVHTRFNQALTQTGRLSSTDPNLQNIPIRLEEGRKIRQAFVPSEPD  649
            Y+ GL      D+ K+HTR+ Q LTQTGRLSS DPNLQNIPIRLE+GR IR+AF PS+ D
Sbjct  591  YVIGLQDYILADG-KIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHED  649

Query  650  WLIFAADYSQIELRVLAHISKDENLIEAFTNDMDIHTKTAMDVFHVS-EDEVTQAMRRQA  708
             +++++DYSQIELRVLAHIS DE+LI AF ++ DIHT TAM VF +    +VT   RR+A
Sbjct  650  AVLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNA  709

Query  709  KAVNFGIVYGISDYGLSQNLGITRKEAGAFIDRYLESFPGVKAYMEESVQEAKQKGYVTT  768
            KAVNFGIVYGISD+GLS+NLGITRK++ ++ID Y+E +PG+KAYME+ V+EAK+KGYV T
Sbjct  710  KAVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVET  769

Query  769  LMQRRRYIPELTSRNFNLRSFAERTAMNTPIQGSAADIIKKAMIDMAAELKEKNLKARLL  828
            L +RRR +P++ SRNFN+RSFAERTA+N+PIQGSAADI+K AMI++   L+   ++A++L
Sbjct  770  LFKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKML  829

Query  829  LQVHDELIFEAPKEEIEILEKLVPEVMEHALALDVPLKADYASGPSWYDAK  879
            LQVHDE+++E P++E+  + KLV + ME A+ L VPL  D ++G SWY+AK
Sbjct  830  LQVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

280) polA in NC_022081


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  697 bits (2636),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 444/891 (50%), Positives = 643/891 (73%), Gaps = 23/891 (2%)

Query  1    MTERKKLVLVDGNSLAYRAFFAL----PLLSNEKGIHTNAVYGFAMILMKMLEDEKPTHM  56
            M +++KL+L+DG+S+A+RAFFAL      + N+ G+HTNA+YGF ++L  M+   +PTH+
Sbjct  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60

Query  57   LVAFDAGKTTFRHSTFKEYKGGRQKTPPELSEQMPFIRELLDAYNISRYELPEYEADDII  116
            LVAFDAGKTTFR   + +YK+GR KTP E+ EQ ++IRE+L A  I+ YEL +YEADDII
Sbjct  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120

Query  117  GTLAVSAEKEG--FEVKVVSGDKDLTQLATGKTTVAITRKGITDVEDYTPEHVQEKYGLT  174
            GTL   AE+    F+V +VSGDKDL QL+  +T V I++KG+++ E++TP  + EK GLT
Sbjct  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180

Query  175  PLQIIDMKGLMGDSSDNIPGVPGVGEKTAIKLLKQFHSVEKLLDSIDEVSGkklkeklee  234
            P Q+ID+K+LMGD SDNIPGV  +GEKT++KLL +F S+E + + ID     K+KE+L +
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  235  ykeQALMSKELATIMTNAPIEVKPEDLDYQGFDREQVVAIFKDLGFNTLLERLSEESGET  294
             ++QA++SK LATI T +PI +  +D+ Y+G D   +  ++ +++F  L   L+   ++ 
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLA---SQM  297

Query  295  AEENFEDINVETAEEITEDMLVSPSALVVEQIGDNYHEEPILGFSIVNETGLYYIPKEIA  354
            ++E    I+ +   +++ D++ +   +  E + DNYH E+I+GF+  +   +Y  + +++
Sbjct  298  PQEPVAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIY-ASTDLS  356

Query  355  I-QSEAFKSWAEDESMKKWV--FDSKRSVVALRWQGIELKGTEFDALLAAYIINPGNSYD  411
            +  +++FK     +  +K +  +D KRS V L   GIEL +  +DA LA Y+++  +  +
Sbjct  357  LLATDSFK-----QVFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-N  410

Query  412  DVASVAKEYGLNIVSKDEAVYGKGAKRAVPAEKELADHLARKASAVNSLRDKLLDALEEN  471
            +++++A+ +    +  D++VYGKGAKRAVP    L +HLARK   +   + ++LD L  +
Sbjct  411  ELSTIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAH  470

Query  472  NQLELYEDLELPLALILGEMESMGVKVDVERLKRMGeelkaklkeyeekIHDIAGEPFNI  531
            +QL+LY+++ELPLA +L+ ME  G+KV+   L+ M+E+ K  +    + I D+AG+ FNI
Sbjct  471  EQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNI  530

Query  532  NSPKQLGVILFEKLGLP--PVKKTKTGYSTSADVLEKLADKHDIVAHILQYRQIGKLQST  589
            NSPKQLG ILFEK+ LP    KKTKTGYST+ DVLE+LA    IVA IL+YRQI KLQST
Sbjct  531  NSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQST  590

Query  590  YIEGLLKVTRKDSHKVHTRFNQALTQTGRLSSTDPNLQNIPIRLEEGRKIRQAFVPSEPD  649
            Y+ GL      D+ K+HTR+ Q LTQTGRLSS DPNLQNIPIRLE+GR IR+AF PS+ D
Sbjct  591  YVIGLQDYILADG-KIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHED  649

Query  650  WLIFAADYSQIELRVLAHISKDENLIEAFTNDMDIHTKTAMDVFHVS-EDEVTQAMRRQA  708
             +++++DYSQIELRVLAHIS DE+LI AF ++ DIHT TAM VF +    +VT   RR+A
Sbjct  650  AVLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNA  709

Query  709  KAVNFGIVYGISDYGLSQNLGITRKEAGAFIDRYLESFPGVKAYMEESVQEAKQKGYVTT  768
            KAVNFGIVYGISD+GLS+NLGITRK++ ++ID Y+E +PG+KAYME+ V+EAK+KGYV T
Sbjct  710  KAVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVET  769

Query  769  LMQRRRYIPELTSRNFNLRSFAERTAMNTPIQGSAADIIKKAMIDMAAELKEKNLKARLL  828
            L +RRR +P++ SRNFN+RSFAERTA+N+PIQGSAADI+K AMI++   L+   ++A++L
Sbjct  770  LFKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKML  829

Query  829  LQVHDELIFEAPKEEIEILEKLVPEVMEHALALDVPLKADYASGPSWYDAK  879
            LQVHDE+++E P++E+  + KLV + ME A+ L VPL  D ++G SWY+AK
Sbjct  830  LQVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

281) polA in NC_007168


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  697 bits (2637),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 422/894 (48%), Positives = 639/894 (72%), Gaps = 37/894 (4%)

Query  2    NKLVLIDGNSLSFRAFYAL----PLLSNKAGIHTNAVYGFAMLLEKIMREEQPSHFLVAF  57
            NKL+LIDG+S++FRAF+AL      + N +G+HTNA+YGF ++L+ +M+  +P+H LVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  58   DAGKTTFRHSKYSEYKGGRQSTPPELSEQFPYIRQLLDTYHIKHYELENYEADDIIGTLS  117
            DAGKTTFR   Y++YK+GR  TP E+ EQF+YIR++L +  I  YELE+YEADDIIGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  118  K--EANDQGFETIIVTGDRDLTQLATDNVTIYYTKKGVTDVDHYTPEFIAEKYDGLNPNQ  175
            K  E  +  F+  IV+GD+DL QL+ +N  +  +KKGV++ +++TP ++ EK  GL PNQ
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEK-MGLTPNQ  183

Query  176  IIDMKGLMGDASDNIPGVAGVGEKTAIKLLKQFNTVEGVYDNIDSVSGKKLKEKLENSRE  235
            +ID+K+LMGD SDNIPGV+ +GEKT++KLL +F ++EG+Y++ID+    K+KE+L N R+
Sbjct  184  FIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRD  243

Query  236  DAFMSKDLATINKNSPIEVTLQDTVLKNQDDNKDkielfkklefkqllSDIDSNNTEEKH  295
            +AF+SK LATIN  SPI + L+D V +  D     +  + ++     + ++    + +  
Sbjct  244  QAFLSKTLATINTASPITIGLDDIVYNGPD-----VASLSQFYDEMDFVQLKKGLASQMP  298

Query  296  EDKVIEVS-NDFNNINFKEL--KEAVIHIEVDGTNYLQDTILKFG------FYDGVDHVV  346
            ++ V  +S ++  N++  +L   E ++ +E    NY +++I+ F+      +Y + D  +
Sbjct  299  QEPVAVISYQEVTNVS-ADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSL  357

Query  347  IDSDQLKE-YPELIKWLENETTEKIVYDAKKTYVVAHRLDIDIKNIVFDVMLASYIIDPS  405
            + +D +K+ +   I            YD K++ V+  +L+I++    +D  LA+Y++   
Sbjct  358  LATDSFKQVFQKPI----------ATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTV  407

Query  406  RTIDDVNSVVSNYNQNFVQDDISIYGKGKKRHVPEDTILNKHIASITEAIYACKREMVAE  465
               ++++++   + +  +++D ++YGKG KR VP+  +L  H+A     +   K +M+  
Sbjct  408  ED-NELSTIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDK  466

Query  466  LESHQQIDLLLNLELPLARILSEMEETGIYTDINDLRQMQSEIQGKLDLLISNIHEAAGE  525
            L +H+Q+DL  N+ELPLA +L+ ME  GI  +   L++M  + +  ++ L  +I + AG+
Sbjct  467  LTAHEQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQ  526

Query  526  EFNINSPKQLGVVLFETLELP--VIKKTKTGYSTAVDVLEQLQGQHPIIDYILEYRQLSK  583
            EFNINSPKQLG +LFE ++LP  + KKTKTGYSTAVDVLE+L    PI+  IL+YRQ++K
Sbjct  527  EFNINSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITK  586

Query  584  LQSTYVEGLQKVISKDNRIHTRFNQTLAQTGRLSSVDPNLQNIPVRLEEGRKIRKAFKPT  643
            LQSTYV GLQ  I  D +IHTR+ Q L+QTGRLSSVDPNLQNIP+RLE+GR IRKAF P+
Sbjct  587  LQSTYVIGLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPS  646

Query  644  SNDSVILSADYSQIELRVLAHITQDESMKEAFINEKDVHTATAMKVFDVE-ANEVNALMR  702
             +D+V+LS+DYSQIELRVLAHI+ DE +  AF +  D+HT+TAM+VF+++ A +V A  R
Sbjct  647  HEDAVLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDR  706

Query  703  RQAKAVNFGIVYGISDYGLSQSLNITRKKAKAFIDDYLASFPGVKQYMSDIVKDAKADGY  762
            R+AKAVNFGIVYGISD+GLS++L ITRK++K++ID Y+  +PG+K YM ++V++AK  GY
Sbjct  707  RNAKAVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGY  766

Query  763  VETLLHRRRYIPDINSRNFNLRGFAERTAMNTPIQGSAADIIKLAMVEFDRQIKQTSYHA  822
            VETL+ RRR +PDINSRNFN+R+FAERTA+N+PIQGSAADI+K+AM+++D+ ++  +++A
Sbjct  767  VETLFKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRA  826

Query  823  QLLLQVHDELIFEVPANEVEDFSLFVEEIMEHALQLDVPLKVDSNYGSTWYDAK  876
            ++LLQVHDE+++EVP +E+  +  +V + ME A++L VPL VD + G +WY+AK
Sbjct  827  KMLLQVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

282) B938_13510 in NC_019842


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  696 bits (2634),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 444/891 (50%), Positives = 643/891 (73%), Gaps = 23/891 (2%)

Query  1    MTERKKLVLVDGNSLAYRAFFAL----PLLSNEKGIHTNAVYGFAMILMKMLEDEKPTHM  56
            M +++KL+L+DG+S+A+RAFFAL      + N+ G+HTNA+YGF ++L  M+   +PTH+
Sbjct  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60

Query  57   LVAFDAGKTTFRHSTFKEYKGGRQKTPPELSEQMPFIRELLDAYKISRYELPEYEADDII  116
            LVAFDAGKTTFR   + +YK+GR KTP E+ EQ ++IRE+L A  I+ YEL +YEADDII
Sbjct  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120

Query  117  GTLAVSAEKEG--FEVKVVSGDKDLTQLATGKTTVAITRKGITDVEDYTPEHVQEKYGLT  174
            GTL   AE+    F+V +VSGDKDL QL+  +T V I++KG+++ E++TP  + EK GLT
Sbjct  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180

Query  175  PLQIIDMKGLMGDSSDNIPGVPGVGEKTAIKLLKQFHSVEKLLDSIDEVSGkklkeklee  234
            P Q+ID+K+LMGD SDNIPGV  +GEKT++KLL +F S+E + + ID     K+KE+L +
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  235  ykeQALMSKELATIMTNAPIEVKPEDLDYQGFDREQVVAIFKDLGFNTLLERLGEESGET  294
             ++QA++SK LATI T +PI +  +D+ Y+G D   +  ++ +++F  L   L+   ++ 
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLA---SQM  297

Query  295  AEENFEDINVETAEEITEDMLVSPSALVVEQIGDNYHEEPILGFSIVNETGLYYIPKEIA  354
            ++E    I+ +   +++ D++ +   +  E + DNYH E+I+GF+  +   +Y  + +++
Sbjct  298  PQEPVAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIY-ASTDLS  356

Query  355  I-QSEAFKSWAEDESMKKWV--FDSKRSVVALRWQGIELKGTEFDALLAAYIINPGNSYD  411
            +  +++FK     +  +K +  +D KRS V L   GIEL +  +DA LA Y+++  +  +
Sbjct  357  LLATDSFK-----QVFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-N  410

Query  412  DVASVAKEYGLNIVSKDEAVYGKGAKRAVPAEKELADHLARKASAVNSLRDKLLDALEEN  471
            +++++A+ +    +  D++VYGKGAKRAVP    L +HLARK   +   + ++LD L  +
Sbjct  411  ELSTIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAH  470

Query  472  NQLELYEDLELPLALILGEMESMGVKVDVERLKRMGeelkaklkeyeekIHDIAGEPFNI  531
            +QL+LY+++ELPLA +L+ ME  G+KV+   L+ M+E+ K  +    + I D+AG+ FNI
Sbjct  471  EQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNI  530

Query  532  NSPKQLGVILFEKLGLP--PVKKTKTGYSTSADVLEKLADKHDIVAHILQYRQIGKLQST  589
            NSPKQLG ILFEK+ LP    KKTKTGYST+ DVLE+LA    IVA IL+YRQI KLQST
Sbjct  531  NSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQST  590

Query  590  YIEGLLKVTREDSHKVHTRFNQALTQTGRLSSTDPNLQNIPIRLEEGRKIRQAFVPSEPD  649
            Y+ GL      D+ K+HTR+ Q LTQTGRLSS DPNLQNIPIRLE+GR IR+AF PS+ D
Sbjct  591  YVIGLQDYILADG-KIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHED  649

Query  650  WLIFAADYSQIELRVLAHISKDENLIEAFTNDMDIHTKTAMDVFHVS-EDEVTQAMRRQA  708
             +++++DYSQIELRVLAHIS DE+LI AF ++ DIHT TAM VF +    +VT   RR+A
Sbjct  650  AVLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNA  709

Query  709  KAVNFGIVYGISDYGLSQNLGITRKEAGAFIDRYLESFPGVKAYMEESVQEAKQKGYVTT  768
            KAVNFGIVYGISD+GLS+NLGITRK++ ++ID Y+E +PG+KAYME+ V+EAK+KGYV T
Sbjct  710  KAVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVET  769

Query  769  LMQRRRYIPELTSRNFNLRSFAERTAMNTPIQGSAADIIKKAMIDMAAELKEKNLKARLL  828
            L +RRR +P++ SRNFN+RSFAERTA+N+PIQGSAADI+K AMI++   L+   ++A++L
Sbjct  770  LFKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKML  829

Query  829  LQVHDELIFEAPKEEIEILEKLVPEVMEHALALDVPLKADYASGPSWYDAK  879
            LQVHDE+++E P++E+  + KLV + ME A+ L VPL  D ++G SWY+AK
Sbjct  830  LQVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

283) polA in NC_020410


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  696 bits (2632),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 444/891 (50%), Positives = 643/891 (73%), Gaps = 23/891 (2%)

Query  1    MTERKKLVLVDGNSLAYRAFFAL----PLLSNEKGIHTNAVYGFAMILMKMLEDEKPTHM  56
            M +++KL+L+DG+S+A+RAFFAL      + N+ G+HTNA+YGF ++L  M+   +PTH+
Sbjct  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60

Query  57   LVAFDAGKTTFRHSTFKEYKGGRQKTPPELSEQMPFIRELLDAYKISRYELPEYEADDII  116
            LVAFDAGKTTFR   + +YK+GR KTP E+ EQ ++IRE+L A  I+ YEL +YEADDII
Sbjct  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120

Query  117  GTLAVSAEKEG--FEVKVVSGDKDLTQLATGKTTVAITRKGITDVEDYTPEHVQEKYGLT  174
            GTL   AE+    F+V +VSGDKDL QL+  +T V I++KG+++ E++TP  + EK GLT
Sbjct  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180

Query  175  PLQIIDMKGLMGDSSDNIPGVPGVGEKTAIKLLKQFHSVEKLLDSIDEVSGkklkeklee  234
            P Q+ID+K+LMGD SDNIPGV  +GEKT++KLL +F S+E + + ID     K+KE+L +
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  235  ykeQALMSKELATIMTNAPIEVKPEDLDYQGFDREQVVAIFKDLGFNTLLERLGEESGET  294
             ++QA++SK LATI T +PI +  +D+ Y+G D   +  ++ +++F  L   L+   ++ 
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLA---SQM  297

Query  295  AEENFEDINVETAEEITEDMLVSPSALVVEQIGDNYHEEPILGFSIVNETGLYYIPKEIA  354
            ++E    I+ +   +++ D++ +   +  E + DNYH E+I+GF+  +   +Y  + +++
Sbjct  298  PQEPVAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIY-ASTDLS  356

Query  355  I-QSEAFKSWAEDESMKKWV--FDSKRSVVALRWQGIELKGTEFDALLAAYIINPGNSYD  411
            +  +++FK     +  +K +  +D KRS V L   GIEL +  +DA LA Y+++  +  +
Sbjct  357  LLATDSFK-----QVFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-N  410

Query  412  DVASVAKEYGLNIVSKDEAVYGKGAKRAVPAEKELADHLARKASAVNSLRDKLLDALEEN  471
            +++++A+ +    +  D++VYGKGAKRAVP    L +HLARK   +   + ++LD L  +
Sbjct  411  ELSTIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAH  470

Query  472  NQLELYEDLELPLALILGEMESMGVKVDVERLKRMGeelkaklkeyeekIHDIAGEPFNI  531
            +QL+LY+++ELPLA +L+ ME  G+KV+   L+ M+E+ K  +    + I D+AG+ FNI
Sbjct  471  EQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNI  530

Query  532  NSPKQLGVILFEKLGLP--PVKKTKTGYSTSADVLEKLADKHDIVAHILQYRQIGKLQST  589
            NSPKQLG ILFEK+ LP    KKTKTGYST+ DVLE+LA    IVA IL+YRQI KLQST
Sbjct  531  NSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQST  590

Query  590  YIEGLLKVTRKDSHKVHTRFNQALTQTGRLSSTDPNLQNIPIRLEEGRKIRQAFVPSEPD  649
            Y+ GL      D+ K+HTR+ Q LTQTGRLSS DPNLQNIPIRLE+GR IR+AF PS+ D
Sbjct  591  YVIGLQDYILADG-KIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHED  649

Query  650  WLIFAADYSQIELRVLAHISKDENLIEAFTNDMDIHTKTAMDVFHVS-EDEVTQAMRRQA  708
             +++++DYSQIELRVLAHIS DE+LI AF ++ DIHT TAM VF +    +VT   RR+A
Sbjct  650  AVLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNA  709

Query  709  KAVNFGIVYGISDYGLSQNLGITRKEAGAFIDRYLESFPGVKAYMEESVQEAKQKGYVTT  768
            KAVNFGIVYGISD+GLS+NLGITRK++ ++ID Y+E +PG+KAYME+ V+EAK+KGYV T
Sbjct  710  KAVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVET  769

Query  769  LMQRRRYIPELTSRNFNLRSFAERTAMNTPIQGSAADIIKKAMIDMAAELKEKNLKARLL  828
            L +RRR +P++ SRNFN+RSFAERTA+N+PIQGSAADI+K AMI++   L+   ++A++L
Sbjct  770  LFKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKML  829

Query  829  LQVHDELIFEAPKEEIEILEKLVPEVMEHALALDVPLKADYASGPSWYDAK  879
            LQVHDE+++E P++E+  + KLV + ME A+ L VPL  D ++G SWY+AK
Sbjct  830  LQVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

284) polA in NC_009725


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  695 bits (2629),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 443/891 (50%), Positives = 643/891 (73%), Gaps = 23/891 (2%)

Query  1    MTERKKLVLVDGNSLAYRAFFAL----PLLSNEKGIHTNAVYGFAMILMKMLEDEKPTHM  56
            M +++KL+L+DG+S+A+RAFFAL      + N+ G+HTNA+YGF ++L  M+   +PTH+
Sbjct  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60

Query  57   LVAFDAGKTTFRHSTFKEYKGGRQKTPPELSEQMPFIRELLDAYKISRYELPEYEADDII  116
            LVAFDAGKTTFR   + +YK+GR KTP E+ EQ ++IRE+L A  I+ YEL +YEADDII
Sbjct  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120

Query  117  GTLAVSAEKEG--FEVKVVSGDKDLTQLATGKTTVAITRKGITDVEDYTPEHVQEKYGLT  174
            GTL   AE+    F+V +VSGDKDL QL+  +T V I++KG+++ E++TP  + EK GLT
Sbjct  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180

Query  175  PLQIIDMKGLMGDSSDNIPGVPGVGEKTAIKLLKQFHSVEKLLDSIDEVSGkklkeklee  234
            P Q+ID+K+LMGD SDNIPGV  +GEKT++KLL +F S+E + + ID     K+KE+L +
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  235  ykeQALMSKELATIMTNAPIEVKPEDLDYKGFDREQVVAIFKDLGFNTLLERLGEESGET  294
             ++QA++SK LATI T +PI +  +D+ Y+G D   +  ++ +++F  L   L+   ++ 
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLA---SQM  297

Query  295  AEENFEDINVETAEEITEDMLVSPSALVVEQIGDNYHEEPILGFSIVNETGLYYIPKEIA  354
            ++E    I+ +   +++ D++ +   +  E + DNYH E+I+GF+  +   +Y  + +++
Sbjct  298  PQEPVAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIY-ASTDLS  356

Query  355  I-QSETFKSWAEDESMKKWV--FDSKRSVVALRWQGIELKGTEFDALLAAYIINPGNSYD  411
            +  +++FK     +  +K +  +D KRS V L   GIEL +  +DA LA Y+++  +  +
Sbjct  357  LLATDSFK-----QVFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-N  410

Query  412  DVASVAKEYGLNIVSKDEAVYGKGAKRAVPAEKELADHLARKASAVNSLRDKLLHALEEN  471
            +++++A+ +    +  D++VYGKGAKRAVP    L +HLARK   +   + ++L+ L  +
Sbjct  411  ELSTIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAH  470

Query  472  NQLELYEDLELPLALILGEMESMGVKVDVERLKRMGeelkaklkeyeekIHDIAGEPFNI  531
            +QL+LY+++ELPLA +L+ ME  G+KV+   L+ M+E+ K  +    + I D+AG+ FNI
Sbjct  471  EQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNI  530

Query  532  NSPKQLGVILFEKLGLP--PVKKTKTGYSTSADVLEKLADKHDIVAHILQYRQIGKLQST  589
            NSPKQLG ILFEK+ LP    KKTKTGYST+ DVLE+LA    IVA IL+YRQI KLQST
Sbjct  531  NSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQST  590

Query  590  YIEGLLKVTRKDSHKVHTRFNQALTQTGRLSSTDPNLQNIPIRLEEGRKIRQAFVPSEPD  649
            Y+ GL      D+ K+HTR+ Q LTQTGRLSS DPNLQNIPIRLE+GR IR+AF PS+ D
Sbjct  591  YVIGLQDYILADG-KIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHED  649

Query  650  WLIFAADYSQIELRVLAHISKDENLIEAFTNDMDIHTKTAMDVFHVS-EDEVTQAMRRQA  708
             +++++DYSQIELRVLAHIS DE+LI AF ++ DIHT TAM VF +    +VT   RR+A
Sbjct  650  AVLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNA  709

Query  709  KAVNFGIVYGISDYGLSQNLGITRKEAGAFIDRYLESFPGVKAYMEESVQEAKQKGYVTT  768
            KAVNFGIVYGISD+GLS+NLGITRK++ ++ID Y+E +PG+KAYME+ V+EAK+KGYV T
Sbjct  710  KAVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVET  769

Query  769  LMQRRRYIPELTSRNFNLRSFAERTAMNTPIQGSAADIIKKAMIDMAAELKEKNLKARLL  828
            L +RRR +P++ SRNFN+RSFAERTA+N+PIQGSAADI+K AMI++   L+   ++A++L
Sbjct  770  LFKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKML  829

Query  829  LQVHDELIFEAPKEEIEILEKLVPEVMEHALALDVPLKADYASGPSWYDAK  879
            LQVHDE+++E P++E+  + KLV + ME A+ L VPL  D ++G SWY+AK
Sbjct  830  LQVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

285) polA in NC_016784


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  694 bits (2624),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 444/891 (50%), Positives = 643/891 (73%), Gaps = 23/891 (2%)

Query  1    MTERKKLVLVDGNSLAYRAFFAL----PLLSNEKGIHTNAVYGFAMILMKMLEDEKPTHM  56
            M +++KL+L+DG+S+A+RAFFAL      + N+ G+HTNA+YGF ++L  M+   +PTH+
Sbjct  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60

Query  57   LVAFDAGKTTFRHSTFKEYKGGRQKTPPELSEQMPFIRELLDAYNISRYELPEYEADDII  116
            LVAFDAGKTTFR   + +YK+GR KTP E+ EQ ++IRE+L A  I+ YEL +YEADDII
Sbjct  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120

Query  117  GTLAVSAEKDG--FEVKVVSGDKDLTQLATGKTTVAITRKGITDVEDYTPEHVREKYGLT  174
            GTL   AE+    F+V +VSGDKDL QL+  +T V I++KG+++ E++TP  + EK GLT
Sbjct  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180

Query  175  PLQIIDMKGLMGDSSDNIPGVPGVGEKTAIKLLKQFHSVEKLLDSIDEVSGkklkeklee  234
            P Q+ID+K+LMGD SDNIPGV  +GEKT++KLL +F S+E + + ID     K+KE+L +
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  235  ykeQALMSKELATIMTNAPIEVKPEDLDYQGFDREQVVAIFKDLGFNTLLERLGEESGET  294
             ++QA++SK LATI T +PI +  +D+ Y+G D   +  ++ +++F  L   L+   ++ 
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLA---SQM  297

Query  295  AEENFEDINVETAEEITEDMLVSPSALVVEQIGDNYHEEPILGFSIVNETGLYYIPKEIA  354
            ++E    I+ +   +++ D++ +   +  E + DNYH E+I+GF+  +   +Y  + +++
Sbjct  298  PQEPVAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIY-ASTDLS  356

Query  355  I-QSEAFKSWAEDESMKKWV--FDSKRSVVALRWQGIELKGTEFDALLAAYIINPGNSYD  411
            +  +++FK     +  +K +  +D KRS V L   GIEL +  +DA LA Y+++  +  +
Sbjct  357  LLATDSFK-----QVFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-N  410

Query  412  DVASVAKEYGLNIVSKDEAVYGKGAKRAVPAEKELADHLARKASAVNSLRDKLLDALEEN  471
            +++++A+ +    +  D++VYGKGAKRAVP    L +HLARK   +   + ++LD L  +
Sbjct  411  ELSTIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAH  470

Query  472  NQLELYEDLELPLALILGEMESMGVKVDVERLKRMGeelkaklkeyeekIHDIAGEPFNI  531
            +QL+LY+++ELPLA +L+ ME  G+KV+   L+ M+E+ K  +    + I D+AG+ FNI
Sbjct  471  EQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNI  530

Query  532  NSPKQLGVILFEKLGLP--PVKKTKTGYSTSADVLEKLADKHDIVAYILQYRQIGKLQST  589
            NSPKQLG ILFEK+ LP    KKTKTGYST+ DVLE+LA    IVA IL+YRQI KLQST
Sbjct  531  NSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQST  590

Query  590  YIEGLLKVTRKDSHKVHTRFNQALTQTGRLSSTDPNLQNIPIRLEEGRKIRQAFVPSEPD  649
            Y+ GL      D+ K+HTR+ Q LTQTGRLSS DPNLQNIPIRLE+GR IR+AF PS+ D
Sbjct  591  YVIGLQDYILADG-KIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHED  649

Query  650  WLIFAADYSQIELRVLAHISKDENLIEAFTNDMDIHTKTAMDVFHVS-EDEVTQAMRRQA  708
             +++++DYSQIELRVLAHIS DE+LI AF ++ DIHT TAM VF +    +VT   RR+A
Sbjct  650  AVLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNA  709

Query  709  KAVNFGIVYGISDYGLSQNLGITRKEAGAFIDRYLESFPGVKAYMEESVQEAKQKGYVTT  768
            KAVNFGIVYGISD+GLS+NLGITRK++ ++ID Y+E +PG+KAYME+ V+EAK+KGYV T
Sbjct  710  KAVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVET  769

Query  769  LMQRRRYIPELTSRNFNLRSFAERTAMNTPIQGSAADIIKKAMIDMAAELKEKNLKARLL  828
            L +RRR +P++ SRNFN+RSFAERTA+N+PIQGSAADI+K AMI++   L+   ++A++L
Sbjct  770  LFKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKML  829

Query  829  LQVHDELIFEAPKEEIEILEKLVPEVMEHALALDVPLKADYASGPSWYDAK  879
            LQVHDE+++E P++E+  + KLV + ME A+ L VPL  D ++G SWY+AK
Sbjct  830  LQVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

286) SLGD_01238 in NC_013893


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  694 bits (2625),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 433/891 (49%), Positives = 640/891 (72%), Gaps = 30/891 (3%)

Query  2    DKLVLIDGNSLSFRAFYAL----PLLSNKAGIHTNAIYGFAMLLEKILKEEQPNHFLVAF  57
            +KL+LIDG+S++FRAF+AL      + N +G+HTNAIYGF ++L+ ++K  +P H LVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  58   DAGKTTFRHEKYSEYKGGRQSTPPELSEQFPYIRQLLDAYHIKYYELENYEADDIIGTLS  117
            DAGKTTFR E Y++YK+GR  TP E+ EQF+YIR++L A  I YYELE+YEADDIIGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  118  KQAEASGL--ETIIITGDRDLTQLATDHVTIYYTKKGVTDVDHYTPEFIAEKYNGLLPKQ  175
            K AE + +  +  I++GD+DL QL+ ++  +  +KKGV++ +++TP ++ EK  GL P+Q
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEK-MGLTPNQ  183

Query  176  IIDMKGLMGDTSDNIPGVAGVGEKTAIKLLNQFHSVEGVYNHLDEVSGKKLKENLENSKA  235
            +ID+K+LMGD SDNIPGV+ +GEKT++KLL++F S+EG+Y+H+D     K+KENL N + 
Sbjct  184  FIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRD  243

Query  236  DAFMSKDLATINCDSPIKVNLKDTIMGDLNDNKDKIELFQKLEFKQLLNDIDSSASENNS  295
            +AF+SK LATIN  SPI + L D +  +  D     ++++ ++F QL +++ S  +++  
Sbjct  244  QAFLSKTLATINTASPITIGLDDIVYNG-PDVASLSQFYDEMDFVQLKKGLASQMPQEPV  302

Query  296  ETEHNFEVIHHFDNINFKKLDNAIIHFEIDGSNYLKDKILKFG------LYAQNQYIVIS  349
                +++ + +     F    + I+ FE    NY ++ I+ F+      +YA  +  +++
Sbjct  303  AVI-SYQEVTNVSADLFS--AEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLA  359

Query  350  AEDIHQYTELIEWLENDHNNKIVFDAKKTYVAAHRLEINLQHIDFDVMLASYIIDPSRTI  409
            ++    + +++      ++    +D K++ V   +L I+L    +D  LA+Y++      
Sbjct  360  TDS---FKQVF------QKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-  409

Query  410  EDVQSVVSYYNQNFVKSDIAVYGKGKKRQVPLDDVLEVHIAAIMQAIYNCKPLMSDILSD  469
            +++ ++   + +  +  D +VYGKG KR VP  DVL  H+A  ++ + + K+ M D L+ 
Sbjct  410  NELSTIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTA  469

Query  470  HNQMDLLNNLELPLARILADMEETGIYTDVNDLKEMQNELQEKLDNLVSEIYEAAGESFN  529
            H+Q+DL +N+ELPLA +LA ME  GI  +   L++M ++ +  ++ L  EIY+ AG+ FN
Sbjct  470  HEQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFN  529

Query  530  INSPKQLGIVLFEtlklp--iikktktGYSTAVDVLEQLQGKHPIIDYILEYRQLSKLQS  587
            INSPKQLG +LFE ++LP  + KKTKTGYSTAVDVLE+L    PI+  IL+YRQ++KLQS
Sbjct  530  INSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQS  589

Query  588  TYVEGLQKVISDDQRIHTRFNQTLAQTGRLSSIDPNLQNIPIRLEEGRKIRKAFKPTSDD  647
            TYV GLQ  I  D +IHTR+ Q L+QTGRLSS+DPNLQNIPIRLE+GR IRKAF P+ +D
Sbjct  590  TYVIGLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHED  649

Query  648  YVILSADYSQIELRVLAHMTQDESLKEAFIHGDDIHAATAMKVFGVEKD-QVNDLMRRQA  706
             V+LS+DYSQIELRVLAH++ DE L  AF +G DIH++TAM+VFG++K  +V    RR+A
Sbjct  650  AVLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNA  709

Query  707  KAVNFGIVYGISDYGLSQNLGITRKKAKAFIDDYLASFPGVKQYMTDIVKDAKANGYVET  766
            KAVNFGIVYGISD+GLS+NLGITRK++K++ID Y+  +PG+K YM ++V++AK +GYVET
Sbjct  710  KAVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVET  769

Query  767  LLHRRRYIPDITSRNFNLRSFAERTAMNTPIQGSAADIIKLAMVQFDKNVRETNYHAKLL  826
            L+ RRR +PDI SRNFN+RSFAERTA+N+PIQGSAADI+K+AM+++DK ++   ++AK+L
Sbjct  770  LFKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKML  829

Query  827  LQVHDELIFEVPKSEVQDFSEFVEEIMDNALTLAVPLLVDSSYGATWYDAK  877
            LQVHDE+++EVP+ E+  +  +V + M+ A+ LAVPL VD S G +WY+AK
Sbjct  830  LQVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

287) polA in NC_017353


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  694 bits (2625),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 433/891 (49%), Positives = 640/891 (72%), Gaps = 30/891 (3%)

Query  2    DKLVLIDGNSLSFRAFYAL----PLLSNKAGIHTNAIYGFAMLLEKILKEEQPNHFLVAF  57
            +KL+LIDG+S++FRAF+AL      + N +G+HTNAIYGF ++L+ ++K  +P H LVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  58   DAGKTTFRHEKYSEYKGGRQSTPPELSEQFPYIRQLLDAYHIKYYELENYEADDIIGTLS  117
            DAGKTTFR E Y++YK+GR  TP E+ EQF+YIR++L A  I YYELE+YEADDIIGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  118  KQAEASGL--ETIIITGDRDLTQLATDHVTIYYTKKGVTDVDHYTPEFIAEKYNGLLPKQ  175
            K AE + +  +  I++GD+DL QL+ ++  +  +KKGV++ +++TP ++ EK  GL P+Q
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEK-MGLTPNQ  183

Query  176  IIDMKGLMGDTSDNIPGVAGVGEKTAIKLLNQFHSVEGVYNHLDEVSGKKLKENLENSKA  235
            +ID+K+LMGD SDNIPGV+ +GEKT++KLL++F S+EG+Y+H+D     K+KENL N + 
Sbjct  184  FIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRD  243

Query  236  DAFMSKDLATINCDSPIKVNLKDTIMGDLNDNKDKIELFQKLEFKQLLNDIDSSASENNS  295
            +AF+SK LATIN  SPI + L D +  +  D     ++++ ++F QL +++ S  +++  
Sbjct  244  QAFLSKTLATINTASPITIGLDDIVYNG-PDVASLSQFYDEMDFVQLKKGLASQMPQEPV  302

Query  296  ETEHNFEVIHHFDNINFKKLDNAIIHFEIDGSNYLKDKILKFG------LYAQNQYIVIS  349
                +++ + +     F    + I+ FE    NY ++ I+ F+      +YA  +  +++
Sbjct  303  AVI-SYQEVTNVSADLFS--AEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLA  359

Query  350  AEDIHQYTELIEWLENDHNNKIVFDAKKTYVAAHRLEINLQHIDFDVMLASYIIDPSRTI  409
            ++    + +++      ++    +D K++ V   +L I+L    +D  LA+Y++      
Sbjct  360  TDS---FKQVF------QKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-  409

Query  410  EDVQSVVSYYNQNFVKSDIAVYGKGKKRQVPLDDVLEVHIAAIMQAIYNCKPLMSDILSD  469
            +++ ++   + +  +  D +VYGKG KR VP  DVL  H+A  ++ + + K+ M D L+ 
Sbjct  410  NELSTIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTA  469

Query  470  HNQMDLLNNLELPLARILADMEETGIYTDVNDLKEMQNELQEKLDNLVSEIYEAAGESFN  529
            H+Q+DL +N+ELPLA +LA ME  GI  +   L++M ++ +  ++ L  EIY+ AG+ FN
Sbjct  470  HEQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFN  529

Query  530  INSPKQLGIVLFEtlklp--iikktktGYSTAVDVLEQLQGKHPIIDYILEYRQLSKLQS  587
            INSPKQLG +LFE ++LP  + KKTKTGYSTAVDVLE+L    PI+  IL+YRQ++KLQS
Sbjct  530  INSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQS  589

Query  588  TYVEGLQKVISDDQRIHTRFNQTLAQTGRLSSIDPNLQNIPIRLEEGRKIRKAFKPTSDD  647
            TYV GLQ  I  D +IHTR+ Q L+QTGRLSS+DPNLQNIPIRLE+GR IRKAF P+ +D
Sbjct  590  TYVIGLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHED  649

Query  648  YVILSADYSQIELRVLAHMTQDESLKEAFIHGDDIHAATAMKVFGVEKD-QVNDLMRRQA  706
             V+LS+DYSQIELRVLAH++ DE L  AF +G DIH++TAM+VFG++K  +V    RR+A
Sbjct  650  AVLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNA  709

Query  707  KAVNFGIVYGISDYGLSQNLGITRKKAKAFIDDYLASFPGVKQYMTDIVKDAKANGYVET  766
            KAVNFGIVYGISD+GLS+NLGITRK++K++ID Y+  +PG+K YM ++V++AK +GYVET
Sbjct  710  KAVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVET  769

Query  767  LLHRRRYIPDITSRNFNLRSFAERTAMNTPIQGSAADIIKLAMVQFDKNVRETNYHAKLL  826
            L+ RRR +PDI SRNFN+RSFAERTA+N+PIQGSAADI+K+AM+++DK ++   ++AK+L
Sbjct  770  LFKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKML  829

Query  827  LQVHDELIFEVPKSEVQDFSEFVEEIMDNALTLAVPLLVDSSYGATWYDAK  877
            LQVHDE+++EVP+ E+  +  +V + M+ A+ LAVPL VD S G +WY+AK
Sbjct  830  LQVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

288) KSO_005970 in NC_020272


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  693 bits (2620),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 443/891 (50%), Positives = 643/891 (73%), Gaps = 23/891 (2%)

Query  1    MTERKKLVLVDGNSLAYRAFFAL----PLLSNEKGIHTNAVYGFAMILMKMLEDEKPTHM  56
            M +++KL+L+DG+S+A+RAFFAL      + N+ G+HTNA+YGF ++L  M+   +PTH+
Sbjct  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60

Query  57   LVAFDAGKTTFRHSTFKEYKGGRQKTPPELSEQMPFIRELLDAYNISRYELPEYEADDII  116
            LVAFDAGKTTFR   + +YK+GR KTP E+ EQ ++IRE+L A  I+ YEL +YEADDII
Sbjct  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120

Query  117  GTLAVSAEKDG--FEVKVVSGDKDLTQLATGKTTVSITRKGITDVEDYTPEHVREKYGLT  174
            GTL   AE+    F+V +VSGDKDL QL+  +T V I++KG+++ E++TP  + EK GLT
Sbjct  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180

Query  175  PLQIIDMKGLMGDSSDNIPGVPGVGEKTAIKLLKQFHSVEKLLDSIDEVSGkklkeklee  234
            P Q+ID+K+LMGD SDNIPGV  +GEKT++KLL +F S+E + + ID     K+KE+L +
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  235  ykeQALMSKELATIMTNAPIEVKPEDLDYQGFDREQVVAIFKDLGFNTLLERLGEESGET  294
             ++QA++SK LATI T +PI +  +D+ Y+G D   +  ++ +++F  L   L+   ++ 
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLA---SQM  297

Query  295  AEENFEDINVETAEEITEDMLVSPSALVVEQIGDNYHEEPILGFSIVNETGLYYIPKEIA  354
            ++E    I+ +   +++ D++ +   +  E + DNYH E+I+GF+  +   +Y  + +++
Sbjct  298  PQEPVAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIY-ASTDLS  356

Query  355  I-QSEAFKSWAEDESMKKWV--FDSKRSVVALRWQGIELKGTEFDALLAAYIINPGNSYD  411
            +  +++FK     +  +K +  +D KRS V L   GIEL +  +DA LA Y+++  +  +
Sbjct  357  LLATDSFK-----QVFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-N  410

Query  412  DVASVAKEYGLNIVSKDEAVYGKGAKRAVPAEKELADHLARKASAVNSLRDKLLDALEEN  471
            +++++A+ +    +  D++VYGKGAKRAVP    L +HLARK   +   + ++LD L  +
Sbjct  411  ELSTIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAH  470

Query  472  NQLELYEDLELPLALILGEMESMGVKVDVERLKRMGeelkaklkeyeekIHDIAGEPFNI  531
            +QL+LY+++ELPLA +L+ ME  G+KV+   L+ M+E+ K  +    + I D+AG+ FNI
Sbjct  471  EQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNI  530

Query  532  NSPKQLGVILFEKLGLP--PVKKTKTGYSTSADVLEKLADKHDIVAYILQYRQIGKLQST  589
            NSPKQLG ILFEK+ LP    KKTKTGYST+ DVLE+LA    IVA IL+YRQI KLQST
Sbjct  531  NSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQST  590

Query  590  YIEGLLKVTRKGSHKVHTRFNQALTQTGRLSSTDPNLQNIPIRLEEGRKIRQAFVPSEPD  649
            Y+ GL      ++ K+HTR+ Q LTQTGRLSS DPNLQNIPIRLE+GR IR+AF PS+ D
Sbjct  591  YVIGLQDYILADG-KIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHED  649

Query  650  WLIFAADYSQIELRVLAHISKDENLIEAFTNDMDIHTKTAMDVFHVS-EDEVTQAMRRQA  708
             +++++DYSQIELRVLAHIS DE+LI AF ++ DIHT TAM VF +    +VT   RR+A
Sbjct  650  AVLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNA  709

Query  709  KAVNFGIVYGISDYGLSQNLGITRKEAGAFIDRYLESFPGVKAYMEESVQEAKQKGYVTT  768
            KAVNFGIVYGISD+GLS+NLGITRK++ ++ID Y+E +PG+KAYME+ V+EAK+KGYV T
Sbjct  710  KAVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVET  769

Query  769  LMQRRRYIPELTSRNFNLRSFAERTAMNTPIQGSAADIIKKAMIDMAAELKEKNLKARLL  828
            L +RRR +P++ SRNFN+RSFAERTA+N+PIQGSAADI+K AMI++   L+   ++A++L
Sbjct  770  LFKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKML  829

Query  829  LQVHDELIFEAPKEEIEILEKLVPEVMEHALALDVPLKADYASGPSWYDAK  879
            LQVHDE+++E P++E+  + KLV + ME A+ L VPL  D ++G SWY+AK
Sbjct  830  LQVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

289) polA in NC_017061


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  693 bits (2620),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 443/891 (50%), Positives = 643/891 (73%), Gaps = 23/891 (2%)

Query  1    MTERKKLVLVDGNSLAYRAFFAL----PLLSNEKGIHTNAVYGFAMILMKMLEDEKPTHM  56
            M +++KL+L+DG+S+A+RAFFAL      + N+ G+HTNA+YGF ++L  M+   +PTH+
Sbjct  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60

Query  57   LVAFDAGKTTFRHSTFKEYKGGRQKTPPELSEQMPFIRELLDAYNISRYELPEYEADDII  116
            LVAFDAGKTTFR   + +YK+GR KTP E+ EQ ++IRE+L A  I+ YEL +YEADDII
Sbjct  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120

Query  117  GTLAVSAEKDG--FEVKVVSGDKDLTQLATGKTTVAITRKGITDVEDYTPEHVQEKYGLT  174
            GTL   AE+    F+V +VSGDKDL QL+  +T V I++KG+++ E++TP  + EK GLT
Sbjct  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180

Query  175  PLQIIDMKGLMGDSSDNIPGVPGVGEKTAIKLLKQFHSVEKLLDSIDEVSGkklkeklee  234
            P Q+ID+K+LMGD SDNIPGV  +GEKT++KLL +F S+E + + ID     K+KE+L +
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  235  ykeQALMSKELATIMTNAPIEVKPEDLDYQGFDREQVVAIFKDLGFNTLLERLGEESGET  294
             ++QA++SK LATI T +PI +  +D+ Y+G D   +  ++ +++F  L   L+   ++ 
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLA---SQM  297

Query  295  AEENFEDINVETAEEITEDMLVSPSALVVEQIGDNYHEEPILGFSIVNETGLYYIPKEIA  354
            ++E    I+ +   +++ D++ +   +  E + DNYH E+I+GF+  +   +Y  + +++
Sbjct  298  PQEPVAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIY-ASTDLS  356

Query  355  I-QSEAFKSWAEDESMKKWV--FDSKRSVVALRWQGIELKGTEFDALLAAYIINPGNSYD  411
            +  +++FK     +  +K +  +D KRS V L   GIEL +  +DA LA Y+++  +  +
Sbjct  357  LLATDSFK-----QVFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-N  410

Query  412  DVASVAKEYGLNIVSKDEAVYGKGAKRAVPAEKELADHLARKASAVNSLRDKLLHALEEN  471
            +++++A+ +    +  D++VYGKGAKRAVP    L +HLARK   +   + ++L+ L  +
Sbjct  411  ELSTIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAH  470

Query  472  NQLELYEDLELPLALILGEMESMGVKVDVERLKRMGeelkaklkeyeekIHDIAGEPFNI  531
            +QL+LY+++ELPLA +L+ ME  G+KV+   L+ M+E+ K  +    + I D+AG+ FNI
Sbjct  471  EQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNI  530

Query  532  NSPKQLGVILFEKLGLP--PVKKTKTGYSTSADVLEKLADKHDIVAYILQYRQIGKLQST  589
            NSPKQLG ILFEK+ LP    KKTKTGYST+ DVLE+LA    IVA IL+YRQI KLQST
Sbjct  531  NSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQST  590

Query  590  YIEGLLKVTRKDSHKVHTRFNQALTQTGRLSSTDPNLQNIPIRLEEGRKIRQAFVPSEPD  649
            Y+ GL      D+ K+HTR+ Q LTQTGRLSS DPNLQNIPIRLE+GR IR+AF PS+ D
Sbjct  591  YVIGLQDYILADG-KIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHED  649

Query  650  WLIFAADYSQIELRVLAHISKDENLIEAFTNDMDIHTKTAMDVFHVS-EDEVTQAMRRQA  708
             +++++DYSQIELRVLAHIS DE+LI AF ++ DIHT TAM VF +    +VT   RR+A
Sbjct  650  AVLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNA  709

Query  709  KAVNFGIVYGISDYGLSQNLGITRKEAGAFIDRYLESFPGVKAYMEESVQEAKQKGYVTT  768
            KAVNFGIVYGISD+GLS+NLGITRK++ ++ID Y+E +PG+KAYME+ V+EAK+KGYV T
Sbjct  710  KAVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVET  769

Query  769  LMQRRRYIPELTSRNFNLRSFAERTAMNTPIQGSAADIIKKAMIDMAAELKEKNLKARLL  828
            L +RRR +P++ SRNFN+RSFAERTA+N+PIQGSAADI+K AMI++   L+   ++A++L
Sbjct  770  LFKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKML  829

Query  829  LQVHDELIFEAPKEEIEILEKLVPEVMEHALALDVPLKADYASGPSWYDAK  879
            LQVHDE+++E P++E+  + KLV + ME A+ L VPL  D ++G SWY+AK
Sbjct  830  LQVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

290) polA in NC_017912


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  693 bits (2620),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 443/891 (50%), Positives = 643/891 (73%), Gaps = 23/891 (2%)

Query  1    MTERKKLVLVDGNSLAYRAFFAL----PLLSNEKGIHTNAVYGFAMILMKMLEDEKPTHM  56
            M +++KL+L+DG+S+A+RAFFAL      + N+ G+HTNA+YGF ++L  M+   +PTH+
Sbjct  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60

Query  57   LVAFDAGKTTFRHSTFKEYKGGRQKTPPELSEQMPFIRELLDAYNISRYELPEYEADDII  116
            LVAFDAGKTTFR   + +YK+GR KTP E+ EQ ++IRE+L A  I+ YEL +YEADDII
Sbjct  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120

Query  117  GTLAVSAEKDG--FEVKVVSGDKDLTQLATGKTTVAITRKGITDVEDYTPEHVQEKYGLT  174
            GTL   AE+    F+V +VSGDKDL QL+  +T V I++KG+++ E++TP  + EK GLT
Sbjct  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180

Query  175  PLQIIDMKGLMGDSSDNIPGVPGVGEKTAIKLLKQFHSVEKLLDSIDEVSGkklkeklee  234
            P Q+ID+K+LMGD SDNIPGV  +GEKT++KLL +F S+E + + ID     K+KE+L +
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  235  ykeQALMSKELATIMTNAPIEVKPEDLDYQGFDREQVVAIFKDLGFNTLLERLGEESGET  294
             ++QA++SK LATI T +PI +  +D+ Y+G D   +  ++ +++F  L   L+   ++ 
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLA---SQM  297

Query  295  AEENFEDINVETAEEITEDMLVSPSALVVEQIGDNYHEEPILGFSIVNETGLYYIPKEIA  354
            ++E    I+ +   +++ D++ +   +  E + DNYH E+I+GF+  +   +Y  + +++
Sbjct  298  PQEPVAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIY-ASTDLS  356

Query  355  I-QSEAFKSWAEDESMKKWV--FDSKRSVVALRWQGIELKGTEFDALLAAYIINPGNSYD  411
            +  +++FK     +  +K +  +D KRS V L   GIEL +  +DA LA Y+++  +  +
Sbjct  357  LLATDSFK-----QVFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-N  410

Query  412  DVASVAKEYGLNIVSKDEAVYGKGAKRAVPAEKELADHLARKASAVNSLRDKLLHALEEN  471
            +++++A+ +    +  D++VYGKGAKRAVP    L +HLARK   +   + ++L+ L  +
Sbjct  411  ELSTIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAH  470

Query  472  NQLELYEDLELPLALILGEMESMGVKVDVERLKRMGeelkaklkeyeekIHDIAGEPFNI  531
            +QL+LY+++ELPLA +L+ ME  G+KV+   L+ M+E+ K  +    + I D+AG+ FNI
Sbjct  471  EQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNI  530

Query  532  NSPKQLGVILFEKLGLP--PVKKTKTGYSTSADVLEKLADKHDIVAYILQYRQIGKLQST  589
            NSPKQLG ILFEK+ LP    KKTKTGYST+ DVLE+LA    IVA IL+YRQI KLQST
Sbjct  531  NSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQST  590

Query  590  YIEGLLKVTRKDSHKVHTRFNQALTQTGRLSSTDPNLQNIPIRLEEGRKIRQAFVPSEPD  649
            Y+ GL      D+ K+HTR+ Q LTQTGRLSS DPNLQNIPIRLE+GR IR+AF PS+ D
Sbjct  591  YVIGLQDYILADG-KIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHED  649

Query  650  WLIFAADYSQIELRVLAHISKDENLIEAFTNDMDIHTKTAMDVFHVS-EDEVTQAMRRQA  708
             +++++DYSQIELRVLAHIS DE+LI AF ++ DIHT TAM VF +    +VT   RR+A
Sbjct  650  AVLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNA  709

Query  709  KAVNFGIVYGISDYGLSQNLGITRKEAGAFIDRYLESFPGVKAYMEESVQEAKQKGYVTT  768
            KAVNFGIVYGISD+GLS+NLGITRK++ ++ID Y+E +PG+KAYME+ V+EAK+KGYV T
Sbjct  710  KAVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVET  769

Query  769  LMQRRRYIPELTSRNFNLRSFAERTAMNTPIQGSAADIIKKAMIDMAAELKEKNLKARLL  828
            L +RRR +P++ SRNFN+RSFAERTA+N+PIQGSAADI+K AMI++   L+   ++A++L
Sbjct  770  LFKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKML  829

Query  829  LQVHDELIFEAPKEEIEILEKLVPEVMEHALALDVPLKADYASGPSWYDAK  879
            LQVHDE+++E P++E+  + KLV + ME A+ L VPL  D ++G SWY+AK
Sbjct  830  LQVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

291) C269_03740 in NC_018631


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  692 bits (2618),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 448/896 (50%), Positives = 653/896 (73%), Gaps = 25/896 (2%)

Query  3    KKLLLIDGNSLAFRAFYAMYNQLDRMISHKGLHTNALVAFNNFLDQIVDPMQPDLAVVAW  62
            +KLLLIDG+S+AFRAF+A+YNQ+DR  +H GLHTNA+ +F+  LD+++  ++P   +VA 
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  63   DAASGKETFRGELFPEYKDGRSKAPSEFKEQFPYLREMVALHGLRNYEQPGLEADDIIGT  122
            DA  GK TFR E++++YK GR+K+P EF+EQF+Y+REM++  G+  YE    EADDIIGT
Sbjct  65   DA--GKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGT  122

Query  123  YSRLGEQAG--YTVIIVTGDQDLTQLATDKITVNVTKKGVTEIERYTPDYIMEKFNLTPL  180
              +++E++   + V IV+GD+DL QL+ ++  V+++KKGV+E+E +TP Y+MEK  LTP 
Sbjct  123  LDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPN  182

Query  181  QIIEKKALTGDTSDNYPGITKVGEKTALKLLAEYHDIDNLYAHVDDMKQSKLKDNLINDR  240
            Q+I+ KAL GD SDN PG+TK+GEKT+LKLL E+  ++ +Y H+D+ K SK+K+NLINDR
Sbjct  183  QFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDR  242

Query  241  QLAFCARKlatiltdatlalplEEIEYRGIDYDNLVTFYENLDFkkqlakikalqkSGQI  300
            + AF ++ LATI T + +++ L++I Y G D  +L  FY+++DF +    +     ++Q+
Sbjct  243  DQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGL-----ASQM  297

Query  301  SGSQTTVEKSINVIKLQDDNLQAVAMLGTKIAFHIEMVGQNYHIDDMVGFVIGSPATGYY  360
            +      + ++ VI  Q+    +  ++++   F +E + +NYH + ++GF  G  +   Y
Sbjct  298  P------QEPVAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWG-HGEQIY  350

Query  361  GSRDVTLLQRPELKSVIENAGIIKNVFNIKAQlillkrlgiklkgtkFDFLLASYLLDTT  420
            +S D++LL    +K V++++      +++K   +LL +LGI L +  +D  LA+YLL T 
Sbjct  351  ASTDLSLLATDSFKQVFQKP---IATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTV  407

Query  421  DNDNELATLAQRF-DLYMTSDEDIYGKGAKFAIPEDDARVLAHLANKADILMQVEQLAFD  479
            + DNEL+T+A+ F D+ +  D+ +YGKGAK A+P+ D  +L HLA K  +L++     +D
Sbjct  408  E-DNELSTIARIFTDISLEEDDTVYGKGAKRAVPDKDV-LLEHLARKVKVLLDSKSQMLD  465

Query  480  ALQEHEQTHLYTEIELPLAQVLADMEYQGIKIDQKRLRDIGSDLEGRIHAIENAIYIEAG  539
             L  HEQ +LY +IELPLA+VLA ME +GIK+++  L+D++ +    I+A+ + IY  AG
Sbjct  466  KLTAHEQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAG  525

Query  540  EKFNINSPKQLGVLLFEKMGLP--VVKRTKTGYSTAVDVLEKLAAQAPIVDHILQYRQLA  597
            + FNINSPKQLG +LFEKM LP  + K+TKTGYSTAVDVLE+LA+ APIV  IL+YRQ++
Sbjct  526  QEFNINSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQIT  585

Query  598  KLKSTYVEGLLTVVHDQDSKIHTRFLQTLTQTGRLSSVDPNLQNIPMRTEEGRQIRTAFV  657
            KL+STYV GL   +   D+KIHTR++Q LTQTGRLSSVDPNLQNIP+R E+GR IR AF 
Sbjct  586  KLQSTYVIGLQDYILA-DGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFT  644

Query  658  PSEPNWQIVGADYSQIELRVLAHMTGDKNMQRAFLNGEDIHAETARAVFGLKDDAPVDAL  717
            PS+ +  ++++DYSQIELRVLAH++GD ++  AF +G DIH+ TA  VFG+   A V A 
Sbjct  645  PSHEDAVLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTAN  704

Query  718  MRRTAKAVNFGIVYGISDFGLANNLGISRAEAKNFIDTYFKEFPQIHAWMAKIKEIAHEQ  777
             RR AKAVNFGIVYGISDFGL+NNLGI+R ++K++IDTYF  +P I A M ++   A ++
Sbjct  705  DRRNAKAVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDK  764

Query  778  GFVETIAKRRRYLPEISSKNFNLRSFAERTAMNSPIQGSAADIIKIAMIKVADALRDHHM  837
            G+VET+ KRRR LP+I+S+NFN+RSFAERTA+NSPIQGSAADI+KIAMI++  AL+    
Sbjct  765  GYVETLFKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGF  824

Query  838  QARMLLQVHDELIFEAPMDEIQELTELVTNVMDSAVVLDVPMRVESHYGNTWYDAK  893
            +A+MLLQVHDE+++E P DE+  +  LV + M++AV L VP+ V+   G++WY+AK
Sbjct  825  RAKMLLQVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

292) polA in NC_018590


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  692 bits (2615),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 436/885 (50%), Positives = 644/885 (73%), Gaps = 20/885 (2%)

Query  12   NKLVLIDGNSIANRAFYAL----PLLNNDKGVYTNAVYGFAMMLMNVLEKEKPSHVLVAF  67
            NKL+LIDG+S+A RAF+AL      ++N+ G+ TNA+YGF +ML +++ + +P+HVLVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  68   DAGKTTFRHTTFKGYKGGRQKTPSELSEQFPFIRELLTAYDIPQYELANYEADDIIGTLT  127
            DAGKTTFR   + +YK+GR KTP E+ EQF++IRE+LTA +I+ YEL +YEADDIIGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  128  KKAEADGM--EVAIITGDRDLTQLASEKTTVYITKKGIADMETNTPETLKEKYNLTPEQI  185
            K AE   +  +V+I++GD+DL QL+ E+T V I+KKG+A+ E  TP  L EK  LTP+Q+
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  186  IDMKGLMGDSSDNIPGIPGVGEKTALKLLHEFGGTVESVLEHAEEISGkklkekvlenke  245
            ID+K+LMGD SDNIPG+  +GEKT+LKLLHEFG ++E++ EH + +   K+KE+++++++
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFG-SLEGIYEHIDGFKTSKMKENLINDRD  243

Query  246  lAILSKELATINVDSPIECTVESTKYDGYQTEKVIPLLKEMNFTTLLKNIEGDTPEEAKE  305
             A+LSK LATIN  SPI   ++   Y+G +   +  +  EM+F  L K + ++ P+E+  
Sbjct  244  QAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEPVA  303

Query  306  LKELSFEIVTELKEKHFGGKTALYVELENDNYHTANFIGLTVHSSQGTYFFTKETAENSE  365
            +  +S++ VT++    F++   +Y E   DNYH   +IG++   ++  Y  T  +   ++
Sbjct  304  V--ISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLATD  361

Query  366  AFREWVESEQTKVVYDAKKTMVAMNRIGLAISGITFDIMLASYLLNPSDSIDDFTSVAVR  425
            +F++    ++    YD K++ V ++++G+ + + ++D  LA+YLL+  +  ++++++A  
Sbjct  362  SFKQ--VFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NELSTIA--  416

Query  426  HDYTEV--ETDEAVYGKGAKRSTPEESIVASHLARKAVAIADLEKRLVADLEENEQLALM  483
            + +T++  E D++VYGKGAKR+ P+  ++  HLARK   + D   +++  L  +EQL L 
Sbjct  417  RIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLY  476

Query  484  EDLELPLTFVLAEMEMQGVSVDTERLENMKVELAGRLKTLEESIHSLAGEEFNINSPKQL  543
            +++ELPL+ VLA ME++G+ V+   L++M  +    + +L + I  +AG+EFNINSPKQL
Sbjct  477  QNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQL  536

Query  544  GVILFEKLGLP--AVKKTKTGYSTAADVLESLSGKHAIIDEILLYRQLGKIQSTYIEGLL  601
            G ILFEK+ LP    KKTKTGYSTA DVLE L+   +I+  IL YRQ+ K+QSTY+ GL 
Sbjct  537  GSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQ  596

Query  602  KVTDKETHKVHTRFNQTLTQTGRLSSVDPNLQNIPIRLEEGRKIRQVFVPSKPGWKMFSA  661
                 +  K+HTR+ Q LTQTGRLSSVDPNLQNIPIRLE+GR IR+ F PS  +  ++S+
Sbjct  597  DYILADG-KIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSS  655

Query  662  DYSQVELRVLAHISEDENLIYAFKHDYDIHTKTAMDVFHVEQD-EVDSLMRRQAKAVNFG  720
            DYSQ+ELRVLAHIS DE+LI AF+++ DIHT TAM VF +++  +V +  RR+AKAVNFG
Sbjct  656  DYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFG  715

Query  721  IVYGISDYGLSQNLGITRKEAKDFIDRYFVSYPAVKEYMQDIVRFAKEKGYVETILHRRR  780
            IVYGISD+GLS+NLGITRK++K +ID YF  YP++K YM+++VR AK+KGYVET++ RRR
Sbjct  716  IVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRR  775

Query  781  YIPEIVSRNFNVRGFAERTAMNTPIQGSAADIIKKAMILMSERLVSEKLEAKLLLQVHDE  840
             +P+I SRNFNVR+FAERTA+N+PIQGSAADI+K AMI +   L +  + AK+LLQVHDE
Sbjct  776  ELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDE  835

Query  841  LIFEAPEAEIAKLEEIVPDVMENAVELSVPLKVDSAFGDTWYDAK  885
            +++E P+ E++ +  +V D ME AV+L+VPL VD + G++WY+AK
Sbjct  836  IVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

293) B1NLA3E_17130 in NC_021171


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  691 bits (2612),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 438/884 (50%), Positives = 651/884 (74%), Gaps = 17/884 (1%)

Query  3    KKLILIDGNSIAYRAFFAL----PLLNNHKGVHTNAVYGFTMILMKILEEEKPTHILVAF  58
            +KL+LIDG+S+A+RAFFAL      ++NH G+HTNA+YGF ++L  ++   +PTH+LVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  59   DAGKTTFRHKTFSEYKGGRQKTPPELSEQFPFIKELLDAYGISRYELENFEADDIIGTMS  118
            DAGKTTFR   +++YK+GR KTP E+ EQF++I+E+L A GI+ YELE++EADDIIGT+ 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  119  RQAEQDG--FEVKVISGDKDLTQLSSDKITVCITRKGITDIESYTPDHIREKYGLSPNQI  176
            + AE+    F+V ++SGDKDL QL+ ++  V I++KG++++E +TP  + EK GL+PNQ+
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  177  IDMKGLMGDQSDNIPGVPGVGEKTAIkllkefetlekllNSIDQVSGNKLKEKLEEFKDQ  236
            ID+K+LMGD+SDNIPGV  +GEKT++KLL EF +LE + + ID    +K+KE+L + +DQ
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRDQ  244

Query  237  AVMSKQLATITTEAPVELQLSEIEYEGFQKDKLVSLFKELEFQTLLDRIGTELVEDTTIE  296
            A +SK LATI T +P+ + L +I Y+G +   L  ++ E++F  L   +++++ ++    
Sbjct  245  AFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEP---  301

Query  297  LQEIDFQIIEEVDKQIFTEDTSLYVEILDDNYNRGEIIGFSLANKNGCYFISTKNALKSP  356
            +  I +Q + +V  ++F+ +  +Y E L DNY+R  IIGF+ ++ +  Y  +  + L + 
Sbjct  302  VAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLATD  361

Query  357  EFKKWAEDEQKRKTVYDAKRSVVSLRHQNIDLKGIEFDLLLASYIVNPAEVIDDIAEIAK  416
             FK   +  QK  + YD KRS V L H  I+L +  +D  LA+Y+++  E  ++++ IA+
Sbjct  362  SFK---QVFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NELSTIAR  417

Query  417  RYGFHDVQSDEAFYGKGAKRQVPEEAKLAEHLVRKVYAMDILTEKLIKELQENQLYELFT  476
             +    ++ D++ YGKGAKR VP+   L EHL RKV  +     +++  L  ++  +L+ 
Sbjct  418  IFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQ  477

Query  477  ELEMPLSLILAEMEFQGVKVDQGRLQKMGQENNEELARLETTIHQLAGEEFNINSPKQLG  536
            ++E+PL+ +LA ME++G+KV+++ LQ M+++N+  +  L   I ++AG+EFNINSPKQLG
Sbjct  478  NIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLG  537

Query  537  IILFEK--LGLNSFKKTKTGYSTSADILEKLENDHDIIKEILHYRQLGKLQSTYIEGLLK  594
             ILFEK  L L+  KKTKTGYST+ D+LE+L     I+  IL+YRQ+ KLQSTY+ GL  
Sbjct  538  SILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQD  597

Query  595  VVDPETLKVHTRYNQALTQTGRLSSTDPNLQNIPIRLEEGRKIRQAFIPSEPGWMMFAAD  654
             + ++  K+HTRY Q LTQTGRLSS DPNLQNIPIRLE+GR IR+AF PS+ + +++++D
Sbjct  598  YILADG-KIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSD  656

Query  655  YSQIELRVLADIAEDEKLIEAFKEGLDIHTKTAMDVFHVAKE-DVTSSMRRQAKAVNFGI  713
            YSQIELRVLA+I+ DE LI AF+EG DIHT TAM VF + K  DVT++ RR+AKAVNFGI
Sbjct  657  YSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGI  716

Query  714  IYGISDYGLSQNLGITRKDAGKFIDLYLQSYPRVKDYMEDIVKDAKQKGFVSTLLHRRRY  773
            +YGISD+GLS+NLGITRK++  +ID Y++ YP +K YME++V++AK+KG+V TL+ RRR 
Sbjct  717  VYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRE  776

Query  774  IPEITSRNFNVRSFAERTAMNTPIQGSAADIIKKAMIDMAERLKTEGIKARLLLQVHDel  833
            +P+I SRNFNVRSFAERTA+N+PIQGSAADI+K AMI++   L++ G++A++LLQVHDE+
Sbjct  777  LPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEI  836

Query  834  ifeapeeeieilkkiVPDVMEHAIELKVPLKVDYAYGPTWFDAK  877
            ++E P++E+  +KK+V D ME A++L VPL VD + G +W++AK
Sbjct  837  VLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

294) polA in NC_009848


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  691 bits (2612),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 441/889 (50%), Positives = 637/889 (72%), Gaps = 19/889 (2%)

Query  1    MTDKKKLVLVDGNSLAYRAFFAL----PLLSNDKGVHTNAIYGFAMILMKMLEDEKPTHM  56
            M +K+KL+L+DG+S+A+RAFFAL      + N+ G+HTNAIYGF ++L  M+   +PTH+
Sbjct  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60

Query  57   LVAFDAGKTTFRHETFKEYKGGRQKTPPELSEQMPFIRELLDAYQVKRYELPQYEADDII  116
            LVAFDAGKTTFR E + +YK+GR KTP E+ EQ ++IRE+L A  +  YEL +YEADDII
Sbjct  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120

Query  117  GTLAVEAEKDG--FEVKIFSGDKDLTQLSTDHTTVAITKKGITEVEYYTPAHIEEKYGLR  174
            GTL   AE+    F+V I SGDKDL QL+ ++T V I+KKG++E E +TPA + EK GL 
Sbjct  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180

Query  175  PDQIIDMKGLMGDSSDNIPGVPGVGEKTAIKLLKQFETVENLLEHIDEVSGkklkeklee  234
            P+Q+ID+K+LMGD SDNIPGV  +GEKT++KLL +F ++E + EHID     K+KE+L +
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  235  fkeQAVMSKELATILVEAPIDVSSKDLAYEGPHMDQVISLYKELGFQTLLERLGEAPETD  294
             ++QA +SK LATI   +PI ++  D+ Y+GP++  +  +Y E++F  L   L+ +   +
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLA-SQMPQ  299

Query  295  EQVEVDALEVKKMTAVTSEMLTDHAALVVEQLGDNYHEADLIGFAIHNENGAFFMTKEDA  354
            E V V  +  + +T V++++++ +  +  E L DNYH   +IGFA  + +  +  T    
Sbjct  300  EPVAV--ISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSL  357

Query  355  LQSEAFKEWVQDETKKKWVFDSKRAVVALRWHDVDLKGVDNDVLLASYVVNPQKTYEDVA  414
            L +++FK+  Q        +D KR+ V L   +++L +   D  LA+Y+++     ++++
Sbjct  358  LATDSFKQVFQKPIA---TYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NELS  413

Query  415  SVAKEYGLNIALS-DEKVYGKGAKQAIPPEDELKEHLGRKAAAISALHDLTLEALEKNDQ  473
            ++A+ +  +I+L  D+ VYGKGAK+A+P  D L EHL+RK   +       L+ L  ++Q
Sbjct  414  TIARIFT-DISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQ  472

Query  474  HELYEDLELPLALILGEMESLGVKVDIKRLENMGeeltkklkeyeetIHRLAGETFNINS  533
             +LY+++ELPLA +L+ ME  G+KV+   L++M+E+    +    + I  +AG+ FNINS
Sbjct  473  LDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINS  532

Query  534  PKQLGVILFEKLGLPI--IKKTKTGYSTSADVLEKLEDKHEIIRSILHYRQIGKLQSTYV  591
            PKQLG ILFEK+ LP+   KKTKTGYST+ DVLE+L     I+  IL+YRQI KLQSTYV
Sbjct  533  PKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYV  592

Query  592  EGLMKVTRKDTHKVHTRFNQALTQTGRLSSTDPNLQNIPIRLEEGRKIRQAFVPSKEGWL  651
             GL      D  K+HTR+ Q LTQTGRLSS DPNLQNIPIRLE+GR IR+AF PS E+ +
Sbjct  593  IGLQDYILADG-KIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAV  651

Query  652  MFAADYSQIELRVLAHISQDENLIEAFTRDMDIHTKTAMDVFHVS-EEEVTSAMRRQAKA  710
            ++++DYSQIELRVLAHIS DE+LI AF  + DIHT TAM VF +    +VT+  RR+AKA
Sbjct  652  LLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKA  711

Query  711  VNFGIVYGISDYGLSQNLGITRKEAAAFIERYLTSFKGVKTYMEEIVQEAKQKGYVTTLL  770
            VNFGIVYGISD+GLS+NLGITRK++ ++I+ Y+  + G+K+YME++V+EAK+KGYV TL+
Sbjct  712  VNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLF  771

Query  771  KRRRYIPDITSRNFNIKSFAERTAMNTPIQGSAADIIKKAMIDMARRLKEEKLQTNLLLQ  830
            KRRR +PDI SRNFN++SFAERTA+N+PIQGSAADI+K AMI++ + L+   +++++LLQ
Sbjct  772  KRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQ  831

Query  831  VHDELIFEAPKEEIAILEKIVPEVMENALQLDVPLKVDFASGPSWYDAK  879
            VHDE+++E P++E++ + K+V + ME A++L VPL VD ++G SWY+AK
Sbjct  832  VHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

295) OEOE_0673 in NC_008528


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  691 bits (2612),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 441/896 (50%), Positives = 648/896 (73%), Gaps = 26/896 (2%)

Query  14   KTLLLIDGNSLAFRAFYAMYNQLDRMVAHTGLHTNALVAFNNFFDQVVEKMNPDYALVAW  73
            + LLLIDG+S+AFRAF+A+YNQ+DR   H+GLHTNA+ +F+  +D+++ ++ P   LVA 
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  74   DAGKGATTFRAKIFDDYKGDRQTTPPELSEQFPYLRKMVDLHGIHSYELPGFEADDIIGT  133
            DAGK  TTFR+ ++ DYK++R  TP E+ EQF+Y+R M+   GI  YEL  +EADDIIGT
Sbjct  65   DAGK--TTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGT  122

Query  134  YSKLAEKAGL--KTTIITGDRDLTQLVTDNVSVNVTKKGVTELDRYTPKFLAEKWGGITP  191
              K+AE++ +    TI++GD+DL QL  +N  V+++KKGV+E++ +TP +L EK G +TP
Sbjct  123  LDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMG-LTP  181

Query  192  SQVIEMKSLTGDTSDHYPGVTKVGLKTAIKLLNEFGSLDGIYQHIDSMKTSKLKENLLND  251
            +Q I++K+L GD SD+ PGVTK+G KT++KLL+EFGSL+GIY+HID+ KTSK+KENL+ND
Sbjct  182  NQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIND  241

Query  252  KESAYRAHELATIRTDAPVELEMKELINQPINFQELIPFYEELDFKVQLAKIHSMQKAGM  311
            ++ A+ +  LATI T +P+ + + +++ +  +   L  FY+E+DF VQL K       G+
Sbjct  242  RDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDF-VQLKK-------GL  293

Query  312  VGQDQEEEKNVQV-TELKAANLDHLSEIKNYLTVYFQTDSDNYHTAKISAFVVGNENDGY  370
             +Q  +E   V    E+   + D +S    +   YF+T  DNYH   I +F  G+ ++ Y
Sbjct  294  ASQMPQEPVAVISYQEVTNVSADLFSAEDIF---YFETLRDNYHREAIIGFAWGHGEQIY  350

Query  371  FASRDLELLNSSVVRKLFKGDLPKYVFNAKELIVLLNRLGLQINNLDFDFLLVSYLLDTT  430
             AS DL LL +   +++F+  ++ Y F+     VLL++LG+++    +D  L +YLL T 
Sbjct  351  -ASTDLSLLATDSFKQVFQKPIATYDFKRSK--VLLSHLGIELVAPSYDARLANYLLSTV  407

Query  431  DNDNQLATLANRF-NVFLESDAEVYGSGVKFKIPENNETLFSHMANKASTISKLHDPSMK  489
            + DN+L+T+A  F ++ LE D  VYG G K  +P++ + L+ H+A K   +       + 
Sbjct  408  E-DNELSTIARIFTDISLEEDDTVYGKGAKRAVPDK-DVLLEHLARKVKVLLDSKSQMLD  465

Query  490  KLSDHQQAELYRQIELPLSKVLASMEINGIKLDQAELKKLGQEFDQRIFELEKQIYEEAG  549
            KL+ H+Q +LY++IELPL++VLA MEI+GIK+++A L+ ++++    I  L ++IY+ AG
Sbjct  466  KLTAHEQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAG  525

Query  550  QEFNINSPKQLADLLFAHMKIP--PIKKTKTGYSTAANVLEELAEKYPFVGLILQYRQLA  607
            QEFNINSPKQL+ +LF  M++P    KKTKTGYSTA +VLE LA   P+V+ IL+YRQ++
Sbjct  526  QEFNINSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQIT  585

Query  608  KLNSTYVKGLLEVVNPDDSKIHTRYLQTLTQTGRLSSVDPNMQNIPDRDEEGKRIRKAFV  667
            KL+STYV GL + + +D +KIHTRY+Q LTQTGRLSSVDPN+QNIP R E+G+ IRKAF 
Sbjct  586  KLQSTYVIGLQDYILAD-GKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFT  644

Query  668  PSHEGWEIFGSDYSQIELRVLAHVTGDENLKKAFESGEDIHAATARSIFGLSTDQKITFD  727
            PSHE+  +++SDYSQIELRVLAH++GDE+L  AF+ G DIH++TA  +FG+     +T +
Sbjct  645  PSHEDAVLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTAN  704

Query  728  QRRRAKAVNFGIVYGISDFGLAQRLGTSRIEGKEIIQTYFHEFPKVKNWIDSIIALAHKQ  787
            +RR AKAVNFGIVYGISDFGL++ LG +R ++K  I+TYF+ +P +K  +++++  A  +
Sbjct  705  DRRNAKAVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDK  764

Query  788  GYVETIAQRRRYLPDIHSKNFNLRSFAERTATNTPIQGSaadiikiamikmqqaLDDNHL  847
            GYVET+ +RRR LPDI+S+NFN+RSFAERTA N+PIQGSAADI+KIAMI++++AL+   +
Sbjct  765  GYVETLFKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGF  824

Query  848  KAKMLLQVHDELIFEAPKQEIDILEELVPKVMDSAVKLNVPLRVEAHHGVNWYDEK  903
            +AKMLLQVHDE+++E P++E+  +  LV   M++AV L VPL V+   G +WY+ K
Sbjct  825  RAKMLLQVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

296) polA in NC_018584


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  690 bits (2609),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 437/885 (50%), Positives = 644/885 (73%), Gaps = 20/885 (2%)

Query  12   NKLVLIDGNSIANRAFYAL----PLLNNDKGVYTNAVYGFAMMLMNVLEKEKPSHVLVAF  67
            NKL+LIDG+S+A RAF+AL      ++N+ G+ TNA+YGF +ML +++ + +P+HVLVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  68   DAGKTTFRHTTFKGYKGGRQKTPSELSEQFPFIRELLTAYDIPQYELANYEADDIIGTLT  127
            DAGKTTFR   + +YK+GR KTP E+ EQF++IRE+LTA +I+ YEL +YEADDIIGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  128  KKAEADGM--EVAIITGDRDLTQLASEKTTVYITKKGIADMETNTPETLKEKYNLTPEQI  185
            K AE   +  +V+I++GD+DL QL+ E+T V I+KKG+A+ E  TP  L EK  LTP+Q+
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  186  IDMKGLMGDSSDNIPGIPGVGEKTALKLLHEFGGTVESVLEHAEEISGkklkekvlenke  245
            ID+K+LMGD SDNIPG+  +GEKT+LKLLHEFG ++E++ EH + +   K+KE+++++++
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFG-SLEGIYEHIDGFKTSKMKENLINDRD  243

Query  246  lAILSKELATINVDSPIECTVESTKYDGYQTEKVIPLLKEMNFTTLLKNIEGDTPEETKE  305
             A+LSK LATIN  SPI   ++   Y+G +   +  +  EM+F  L K + ++ P+E   
Sbjct  244  QAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEPVA  303

Query  306  LKELSFEIVTELKEKHFGGKTALYVELENDNYHTANFIGLTVHSSQGTYFFTKETAESSE  365
            +  +S++ VT++    F++   +Y E   DNYH   +IG++   ++  Y  T  +  +++
Sbjct  304  V--ISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLATD  361

Query  366  VFRKWVESDQTKVVYDAKKTMVAMNRIGLAISGITFDIMLASYLLNPSDSIDDFTSVAIR  425
             F++    ++    YD K++ V ++++G+ + + ++D  LA+YLL+  +  ++++++A  
Sbjct  362  SFKQ--VFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NELSTIA--  416

Query  426  HDYTEV--ETDEAVYGKGAKRSTPEESIVAAHLARKAVAIADLEKRLVDDLEENEQLALM  483
            + +T++  E D++VYGKGAKR+ P+  ++  HLARK   + D   +++D L  +EQL L 
Sbjct  417  RIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLY  476

Query  484  EDLELPLTFVLAEMEMQGVSVDTERLENMKVELAGRLKTLEESIHSLAGEEFNINSPKQL  543
            +++ELPL+ VLA ME++G+ V+   L++M  +    + +L + I  +AG+EFNINSPKQL
Sbjct  477  QNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQL  536

Query  544  GVILFEKLGLP--AVKKTKTGYSTAADVLESLSGKHAIIDEILLYRQLGKIQSTYIEGLL  601
            G ILFEK+ LP    KKTKTGYSTA DVLE L+   +I+  IL YRQ+ K+QSTY+ GL 
Sbjct  537  GSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQ  596

Query  602  KVTDKETHKVHTRFNQTLTQTGRLSSVDPNLQNIPIRLEEGRKIRQVFVPSKPGWKMFSA  661
                 +  K+HTR+ Q LTQTGRLSSVDPNLQNIPIRLE+GR IR+ F PS  +  ++S+
Sbjct  597  DYILADG-KIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSS  655

Query  662  DYSQVELRVLAHISEDENLIYAFKHDYDIHTKTAMDVFHVEQD-EVDSLMRRQAKAVNFG  720
            DYSQ+ELRVLAHIS DE+LI AF+++ DIHT TAM VF +++  +V +  RR+AKAVNFG
Sbjct  656  DYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFG  715

Query  721  IVYGISDYGLSQNLGITRKEAKDFIDRYFVSYPAVKEYMQDIVRFAKEKGYVETILHRRR  780
            IVYGISD+GLS+NLGITRK++K +ID YF  YP++K YM+++VR AK+KGYVET++ RRR
Sbjct  716  IVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRR  775

Query  781  YIPEIVSRNFNVRGFAERTAMNTPIQGSAADIIKKAMILMSERLVSEKLEAKLLLQVHDE  840
             +P+I SRNFNVR+FAERTA+N+PIQGSAADI+K AMI +   L +  + AK+LLQVHDE
Sbjct  776  ELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDE  835

Query  841  LIFEAPEAEIAKLEEIVPDVMENAVELSVPLKVDSAFGDTWYDAK  885
            +++E P+ E++ +  +V D ME AV+L+VPL VD + G++WY+AK
Sbjct  836  IVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

297) LM220_12122 in NC_021830


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  690 bits (2609),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 437/885 (50%), Positives = 644/885 (73%), Gaps = 20/885 (2%)

Query  12   NKLVLIDGNSIANRAFYAL----PLLNNDKGVYTNAVYGFAMMLMNVLEKEKPSHVLVAF  67
            NKL+LIDG+S+A RAF+AL      ++N+ G+ TNA+YGF +ML +++ + +P+HVLVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  68   DAGKTTFRHTTFKGYKGGRQKTPSELSEQFPFIRELLTAYDIPQYELANYEADDIIGTLT  127
            DAGKTTFR   + +YK+GR KTP E+ EQF++IRE+LTA +I+ YEL +YEADDIIGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  128  KKAEADGM--EVAIITGDRDLTQLASEKTTVYITKKGIADMETNTPETLKEKYNLTPEQI  185
            K AE   +  +V+I++GD+DL QL+ E+T V I+KKG+A+ E  TP  L EK  LTP+Q+
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  186  IDMKGLMGDSSDNIPGIPGVGEKTALKLLHEFGGTVESVLEHAEEISGkklkekvlenke  245
            ID+K+LMGD SDNIPG+  +GEKT+LKLLHEFG ++E++ EH + +   K+KE+++++++
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFG-SLEGIYEHIDGFKTSKMKENLINDRD  243

Query  246  lAILSKELATINVDSPIECTVESTKYDGYQTEKVIPLLKEMNFTTLLKNIEGDTPEETKE  305
             A+LSK LATIN  SPI   ++   Y+G +   +  +  EM+F  L K + ++ P+E   
Sbjct  244  QAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEPVA  303

Query  306  LKELSFEIVTELKEKHFGGKTALYVELENDNYHTANFIGLTVHSSQGTYFFTKETAESSE  365
            +  +S++ VT++    F++   +Y E   DNYH   +IG++   ++  Y  T  +  +++
Sbjct  304  V--ISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLATD  361

Query  366  VFRKWVESDQTKVVYDAKKTMVAMNRIGLAISGITFDIMLASYLLNPSDSIDDFTSVAIR  425
             F++    ++    YD K++ V ++++G+ + + ++D  LA+YLL+  +  ++++++A  
Sbjct  362  SFKQ--VFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NELSTIA--  416

Query  426  HDYTEV--ETDEAVYGKGAKRSTPEESIVAAHLARKAVAIADLEKRLVDDLEENEQLALM  483
            + +T++  E D++VYGKGAKR+ P+  ++  HLARK   + D   +++D L  +EQL L 
Sbjct  417  RIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLY  476

Query  484  EDLELPLTFVLAEMEMQGVSVDTERLENMKVELAGRLKTLEESIHSLAGEEFNINSPKQL  543
            +++ELPL+ VLA ME++G+ V+   L++M  +    + +L + I  +AG+EFNINSPKQL
Sbjct  477  QNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQL  536

Query  544  GVILFEKLGLP--AVKKTKTGYSTAADVLESLSGKHAIIDEILLYRQLGKIQSTYIEGLL  601
            G ILFEK+ LP    KKTKTGYSTA DVLE L+   +I+  IL YRQ+ K+QSTY+ GL 
Sbjct  537  GSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQ  596

Query  602  KVTDKETHKVHTRFNQTLTQTGRLSSVDPNLQNIPIRLEEGRKIRQVFVPSKPGWKMFSA  661
                 +  K+HTR+ Q LTQTGRLSSVDPNLQNIPIRLE+GR IR+ F PS  +  ++S+
Sbjct  597  DYILADG-KIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSS  655

Query  662  DYSQVELRVLAHISEDENLIYAFKHDYDIHTKTAMDVFHVEQD-EVDSLMRRQAKAVNFG  720
            DYSQ+ELRVLAHIS DE+LI AF+++ DIHT TAM VF +++  +V +  RR+AKAVNFG
Sbjct  656  DYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFG  715

Query  721  IVYGISDYGLSQNLGITRKEAKDFIDRYFVSYPAVKEYMQDIVRFAKEKGYVETILHRRR  780
            IVYGISD+GLS+NLGITRK++K +ID YF  YP++K YM+++VR AK+KGYVET++ RRR
Sbjct  716  IVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRR  775

Query  781  YIPEIVSRNFNVRGFAERTAMNTPIQGSAADIIKKAMILMSERLVSEKLEAKLLLQVHDE  840
             +P+I SRNFNVR+FAERTA+N+PIQGSAADI+K AMI +   L +  + AK+LLQVHDE
Sbjct  776  ELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDE  835

Query  841  LIFEAPEAEIAKLEEIVPDVMENAVELSVPLKVDSAFGDTWYDAK  885
            +++E P+ E++ +  +V D ME AV+L+VPL VD + G++WY+AK
Sbjct  836  IVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

298) LM1816_06755 in NC_021829


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  690 bits (2608),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 437/885 (50%), Positives = 644/885 (73%), Gaps = 20/885 (2%)

Query  12   NKLVLIDGNSIANRAFYAL----PLLNNDKGVYTNAVYGFAMMLMNVLEKEKPSHVLVAF  67
            NKL+LIDG+S+A RAF+AL      ++N+ G+ TNA+YGF +ML +++ + +P+HVLVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  68   DAGKTTFRHTTFKGYKGGRQKTPSELSEQFPFIRELLTAYDIPQYELANYEADDIIGTLT  127
            DAGKTTFR   + +YK+GR KTP E+ EQF++IRE+LTA +I+ YEL +YEADDIIGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  128  KKAEADGM--EVAIITGDRDLTQLASEKTTVYITKKGIADMETNTPETLKEKYNLTPQQI  185
            K AE   +  +V+I++GD+DL QL+ E+T V I+KKG+A+ E  TP  L EK  LTP+Q+
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  186  IDMKGLMGDSSDNIPGIPGVGEKTALKLLHEFGGTVESVLEHAEEISGkklkekvlenke  245
            ID+K+LMGD SDNIPG+  +GEKT+LKLLHEFG ++E++ EH + +   K+KE+++++++
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFG-SLEGIYEHIDGFKTSKMKENLINDRD  243

Query  246  lAILSKELATINVDSPIECTVESTKYDGYQTEKVIPLLKEMNFTTLLKNIEGDTPEETKE  305
             A+LSK LATIN  SPI   ++   Y+G +   +  +  EM+F  L K + ++ P+E   
Sbjct  244  QAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEPVA  303

Query  306  LKELSFEIVTELKEKHFGGKTALYVELENDNYHTANFIGLTVHSSQGTYFFTKETAESSE  365
            +  +S++ VT++    F++   +Y E   DNYH   +IG++   ++  Y  T  +  +++
Sbjct  304  V--ISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLATD  361

Query  366  VFRKWVESDQTKVVYDAKKTMVAMNRIGLAISGITFDIMLASYLLNPSDSIDDFTSVAIR  425
             F++    ++    YD K++ V ++++G+ + + ++D  LA+YLL+  +  ++++++A  
Sbjct  362  SFKQ--VFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NELSTIA--  416

Query  426  HDYTEV--ETDEAVYGKGAKRSTPEESIVAAHLARKAVAIADLEKRLVDDLEENEQLALM  483
            + +T++  E D++VYGKGAKR+ P+  ++  HLARK   + D   +++D L  +EQL L 
Sbjct  417  RIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLY  476

Query  484  EDLELPLTFVLAEMEMQGVSVDTERLENMKVELAGRLKTLEESIHSLAGEEFNINSPKQL  543
            +++ELPL+ VLA ME++G+ V+   L++M  +    + +L + I  +AG+EFNINSPKQL
Sbjct  477  QNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQL  536

Query  544  GVILFEKLGLP--AVKKTKTGYSTAADVLESLSGKHAIIDEILLYRQLGKIQSTYIEGLL  601
            G ILFEK+ LP    KKTKTGYSTA DVLE L+   +I+  IL YRQ+ K+QSTY+ GL 
Sbjct  537  GSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQ  596

Query  602  KVTDKETHKVHTRFNQTLTQTGRLSSVDPNLQNIPIRLEEGRKIRQVFVPSKPGWKMFSA  661
                 +  K+HTR+ Q LTQTGRLSSVDPNLQNIPIRLE+GR IR+ F PS  +  ++S+
Sbjct  597  DYILADG-KIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSS  655

Query  662  DYSQVELRVLAHISEDENLIYAFKHDYDIHTKTAMDVFHVEQD-EVDSLMRRQAKAVNFG  720
            DYSQ+ELRVLAHIS DE+LI AF+++ DIHT TAM VF +++  +V +  RR+AKAVNFG
Sbjct  656  DYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFG  715

Query  721  IVYGISDYGLSQNLGITRKEAKDFIDRYFVSYPAVKEYMQDIVRFAKEKGYVETILHRRR  780
            IVYGISD+GLS+NLGITRK++K +ID YF  YP++K YM+++VR AK+KGYVET++ RRR
Sbjct  716  IVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRR  775

Query  781  YIPEIVSRNFNVRGFAERTAMNTPIQGSAADIIKKAMILMSERLVSEKLEAKLLLQVHDE  840
             +P+I SRNFNVR+FAERTA+N+PIQGSAADI+K AMI +   L +  + AK+LLQVHDE
Sbjct  776  ELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDE  835

Query  841  LIFEAPEAEIAKLEEIVPDVMENAVELSVPLKVDSAFGDTWYDAK  885
            +++E P+ E++ +  +V D ME AV+L+VPL VD + G++WY+AK
Sbjct  836  IVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

299) polA in NC_018642


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  690 bits (2608),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 437/885 (50%), Positives = 644/885 (73%), Gaps = 20/885 (2%)

Query  12   NKLVLIDGNSIANRAFYAL----PLLNNDKGVYTNAVYGFAMMLMNVLEKEKPSHVLVAF  67
            NKL+LIDG+S+A RAF+AL      ++N+ G+ TNA+YGF +ML +++ + +P+HVLVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  68   DAGKTTFRHTTFKGYKGGRQKTPSELSEQFPFIRELLTAYDIPQYELANYEADDIIGTLT  127
            DAGKTTFR   + +YK+GR KTP E+ EQF++IRE+LTA +I+ YEL +YEADDIIGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  128  KKAEADGM--EVAIITGDRDLTQLASEKTTVYITKKGIADMETNTPETLKEKYNLTPQQI  185
            K AE   +  +V+I++GD+DL QL+ E+T V I+KKG+A+ E  TP  L EK  LTP+Q+
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  186  IDMKGLMGDSSDNIPGIPGVGEKTALKLLHEFGGTVESVLEHAEEISGkklkekvlenke  245
            ID+K+LMGD SDNIPG+  +GEKT+LKLLHEFG ++E++ EH + +   K+KE+++++++
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFG-SLEGIYEHIDGFKTSKMKENLINDRD  243

Query  246  lAILSKELATINVDSPIECTVESTKYDGYQTEKVIPLLKEMNFTTLLKNIEGDTPEETKE  305
             A+LSK LATIN  SPI   ++   Y+G +   +  +  EM+F  L K + ++ P+E   
Sbjct  244  QAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEPVA  303

Query  306  LKELSFEIVTELKEKHFGGKTALYVELENDNYHTANFIGLTVHSSQGTYFFTKETAESSE  365
            +  +S++ VT++    F++   +Y E   DNYH   +IG++   ++  Y  T  +  +++
Sbjct  304  V--ISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLATD  361

Query  366  VFRKWVESDQTKVVYDAKKTMVAMNRIGLAISGITFDIMLASYLLNPSDSIDDFTSVAIR  425
             F++    ++    YD K++ V ++++G+ + + ++D  LA+YLL+  +  ++++++A  
Sbjct  362  SFKQ--VFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NELSTIA--  416

Query  426  HDYTEV--ETDEAVYGKGAKRSTPEESIVAAHLARKAVAIADLEKRLVDDLEENEQLALM  483
            + +T++  E D++VYGKGAKR+ P+  ++  HLARK   + D   +++D L  +EQL L 
Sbjct  417  RIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLY  476

Query  484  EDLELPLTFVLAEMEMQGVSVDTERLENMKVELAGRLKTLEESIHSLAGEEFNINSPKQL  543
            +++ELPL+ VLA ME++G+ V+   L++M  +    + +L + I  +AG+EFNINSPKQL
Sbjct  477  QNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQL  536

Query  544  GVILFEKLGLP--AVKKTKTGYSTAADVLESLSGKHAIIDEILLYRQLGKIQSTYIEGLL  601
            G ILFEK+ LP    KKTKTGYSTA DVLE L+   +I+  IL YRQ+ K+QSTY+ GL 
Sbjct  537  GSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQ  596

Query  602  KVTDKETHKVHTRFNQTLTQTGRLSSVDPNLQNIPIRLEEGRKIRQVFVPSKPGWKMFSA  661
                 +  K+HTR+ Q LTQTGRLSSVDPNLQNIPIRLE+GR IR+ F PS  +  ++S+
Sbjct  597  DYILADG-KIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSS  655

Query  662  DYSQVELRVLAHISEDENLIYAFKHDYDIHTKTAMDVFHVEQD-EVDSLMRRQAKAVNFG  720
            DYSQ+ELRVLAHIS DE+LI AF+++ DIHT TAM VF +++  +V +  RR+AKAVNFG
Sbjct  656  DYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFG  715

Query  721  IVYGISDYGLSQNLGITRKEAKDFIDRYFVSYPAVKEYMQDIVRFAKEKGYVETILHRRR  780
            IVYGISD+GLS+NLGITRK++K +ID YF  YP++K YM+++VR AK+KGYVET++ RRR
Sbjct  716  IVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRR  775

Query  781  YIPEIVSRNFNVRGFAERTAMNTPIQGSAADIIKKAMILMSERLVSEKLEAKLLLQVHDE  840
             +P+I SRNFNVR+FAERTA+N+PIQGSAADI+K AMI +   L +  + AK+LLQVHDE
Sbjct  776  ELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDE  835

Query  841  LIFEAPEAEIAKLEEIVPDVMENAVELSVPLKVDSAFGDTWYDAK  885
            +++E P+ E++ +  +V D ME AV+L+VPL VD + G++WY+AK
Sbjct  836  IVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

300) polA in NC_018587


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  690 bits (2608),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 437/885 (50%), Positives = 644/885 (73%), Gaps = 20/885 (2%)

Query  12   NKLVLIDGNSIANRAFYAL----PLLNNDKGVYTNAVYGFAMMLMNVLEKEKPSHVLVAF  67
            NKL+LIDG+S+A RAF+AL      ++N+ G+ TNA+YGF +ML +++ + +P+HVLVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  68   DAGKTTFRHTTFKGYKGGRQKTPSELSEQFPFIRELLTAYDIPQYELANYEADDIIGTLT  127
            DAGKTTFR   + +YK+GR KTP E+ EQF++IRE+LTA +I+ YEL +YEADDIIGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  128  KKAEADGM--EVAIITGDRDLTQLASEKTTVYITKKGIADMETNTPETLKEKYNLTPQQI  185
            K AE   +  +V+I++GD+DL QL+ E+T V I+KKG+A+ E  TP  L EK  LTP+Q+
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  186  IDMKGLMGDSSDNIPGIPGVGEKTALKLLHEFGGTVESVLEHAEEISGkklkekvlenke  245
            ID+K+LMGD SDNIPG+  +GEKT+LKLLHEFG ++E++ EH + +   K+KE+++++++
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFG-SLEGIYEHIDGFKTSKMKENLINDRD  243

Query  246  lAILSKELATINVDSPIECTVESTKYDGYQTEKVIPLLKEMNFTTLLKNIEGDTPEETKE  305
             A+LSK LATIN  SPI   ++   Y+G +   +  +  EM+F  L K + ++ P+E   
Sbjct  244  QAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEPVA  303

Query  306  LKELSFEIVTELKEKHFGGKTALYVELENDNYHTANFIGLTVHSSQGTYFFTKETAESSE  365
            +  +S++ VT++    F++   +Y E   DNYH   +IG++   ++  Y  T  +  +++
Sbjct  304  V--ISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLATD  361

Query  366  VFRKWVESDQTKVVYDAKKTMVAMNRIGLAISGITFDIMLASYLLNPSDSIDDFTSVAIR  425
             F++    ++    YD K++ V ++++G+ + + ++D  LA+YLL+  +  ++++++A  
Sbjct  362  SFKQ--VFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NELSTIA--  416

Query  426  HDYTEV--ETDEAVYGKGAKRSTPEESIVAAHLARKAVAIADLEKRLVDDLEENEQLALM  483
            + +T++  E D++VYGKGAKR+ P+  ++  HLARK   + D   +++D L  +EQL L 
Sbjct  417  RIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLY  476

Query  484  EDLELPLTFVLAEMEMQGVSVDTERLENMKVELAGRLKTLEESIHSLAGEEFNINSPKQL  543
            +++ELPL+ VLA ME++G+ V+   L++M  +    + +L + I  +AG+EFNINSPKQL
Sbjct  477  QNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQL  536

Query  544  GVILFEKLGLP--AVKKTKTGYSTAADVLESLSGKHAIIDEILLYRQLGKIQSTYIEGLL  601
            G ILFEK+ LP    KKTKTGYSTA DVLE L+   +I+  IL YRQ+ K+QSTY+ GL 
Sbjct  537  GSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQ  596

Query  602  KVTDKETHKVHTRFNQTLTQTGRLSSVDPNLQNIPIRLEEGRKIRQVFVPSKPGWKMFSA  661
                 +  K+HTR+ Q LTQTGRLSSVDPNLQNIPIRLE+GR IR+ F PS  +  ++S+
Sbjct  597  DYILADG-KIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSS  655

Query  662  DYSQVELRVLAHISEDENLIYAFKHDYDIHTKTAMDVFHVEQD-EVDSLMRRQAKAVNFG  720
            DYSQ+ELRVLAHIS DE+LI AF+++ DIHT TAM VF +++  +V +  RR+AKAVNFG
Sbjct  656  DYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFG  715

Query  721  IVYGISDYGLSQNLGITRKEAKDFIDRYFVSYPAVKEYMQDIVRFAKEKGYVETILHRRR  780
            IVYGISD+GLS+NLGITRK++K +ID YF  YP++K YM+++VR AK+KGYVET++ RRR
Sbjct  716  IVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRR  775

Query  781  YIPEIVSRNFNVRGFAERTAMNTPIQGSAADIIKKAMILMSERLVSEKLEAKLLLQVHDE  840
             +P+I SRNFNVR+FAERTA+N+PIQGSAADI+K AMI +   L +  + AK+LLQVHDE
Sbjct  776  ELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDE  835

Query  841  LIFEAPEAEIAKLEEIVPDVMENAVELSVPLKVDSAFGDTWYDAK  885
            +++E P+ E++ +  +V D ME AV+L+VPL VD + G++WY+AK
Sbjct  836  IVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

301) polA in NC_017529


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  690 bits (2610),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 435/885 (50%), Positives = 643/885 (73%), Gaps = 20/885 (2%)

Query  12   NKLVLIDGNSIANRAFYAL----PLLNNDKGVYTNAVYGFAMMLMNVLEKEKPSHVLVAF  67
            NKL+LIDG+S+A RAF+AL      ++N+ G+ TNA+YGF +ML +++ + +P+HVLVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  68   DAGKTTFRHTTFKGYKGGRQKTPSELSEQFPFIRELLTAYDIPQYELANYEADDIIGTLT  127
            DAGKTTFR   + +YK+GR KTP E+ EQF++IRE+LTA +I+ YEL +YEADDIIGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  128  KKAEADGM--EVAIITGDRDLTQLASEKTTVYITKKGIADMETNTPETLKEKYNLTPEQI  185
            K AE   +  +V+I++GD+DL QL+ E+T V I+KKG+A+ E  TP  L EK  LTP+Q+
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  186  IDMKGLMGDSSDNIPGIPGVGEKTALKLLHEFGGTVESVLEHAEEISGkklkekvlenke  245
            ID+K+LMGD SDNIPG+  +GEKT+LKLLHEFG ++E++ EH + +   K+KE+++++++
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFG-SLEGIYEHIDGFKTSKMKENLINDRD  243

Query  246  lAILSKELATINVDSPIECTVESTKYDGYQTEKVIPLLKEMNFTTLLKNIEGDTPEEAKE  305
             A+LSK LATIN  SPI   ++   Y+G +   +  +  EM+F  L K + ++ P+E+  
Sbjct  244  QAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEPVA  303

Query  306  LKELSFEIVTELKEKHFGGKTALYVELENDNYHTSNFIGLTVHSSQGTYFFTKETAENSE  365
            +  +S++ VT++    F++   +Y E   DNYH   +IG++   ++  Y  T  +   ++
Sbjct  304  V--ISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLATD  361

Query  366  AFREWVESEQTKVVYDAKKTMVAMNRIGLAISGITFDIMLASYLLNPSDSIDDFTSVAVR  425
            +F++    ++    YD K++ V ++++G+ + + ++D  LA+YLL+  +  ++++++A  
Sbjct  362  SFKQ--VFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NELSTIA--  416

Query  426  HDYTEV--ETDEAVYGKGAKRSTPEESIVASHLARKAVAIADLEKRLVADLEENEQLALM  483
            + +T++  E D++VYGKGAKR+ P+  ++  HLARK   + D   +++  L  +EQL L 
Sbjct  417  RIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLY  476

Query  484  EDLELPLTFVLAEMEMQGVSVDTERLENMKVELAGRLKTLEESIHSLAGEAFNINSPKQL  543
            +++ELPL+ VLA ME++G+ V+   L++M  +    + +L + I  +AG+ FNINSPKQL
Sbjct  477  QNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQL  536

Query  544  GVILFEKLGLP--AVKKTKTGYSTAADVLESLSGKHAIIDEILLYRQLGKIQSTYIEGLL  601
            G ILFEK+ LP    KKTKTGYSTA DVLE L+   +I+  IL YRQ+ K+QSTY+ GL 
Sbjct  537  GSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQ  596

Query  602  KVTDKETHKVHTRFNQTLTQTGRLSSVDPNLQNIPIRLEEGRKIRQVFVPSKPGWKMFSA  661
                 +  K+HTR+ Q LTQTGRLSSVDPNLQNIPIRLE+GR IR+ F PS  +  ++S+
Sbjct  597  DYILADG-KIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSS  655

Query  662  DYSQVELRVLAHISEDENLIYAFKHDYDIHTKTAMDVFHVEQD-EVDSLMRRQAKAVNFG  720
            DYSQ+ELRVLAHIS DE+LI AF+++ DIHT TAM VF +++  +V +  RR+AKAVNFG
Sbjct  656  DYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFG  715

Query  721  IVYGISDYGLSQNLGITRKEAKDFIDRYFVSYPAVKEYMQDIVRFAKEKGYVETILHRRR  780
            IVYGISD+GLS+NLGITRK++K +ID YF  YP++K YM+++VR AK+KGYVET++ RRR
Sbjct  716  IVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRR  775

Query  781  YIPEIVSRNFNVRGFAERTAMNTPIQGSAADIIKKAMILMSERLVSEKLEAKLLLQVHDE  840
             +P+I SRNFNVR+FAERTA+N+PIQGSAADI+K AMI +   L +  + AK+LLQVHDE
Sbjct  776  ELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDE  835

Query  841  LIFEAPEAEIAKLEEIVPDVMENAVELSVPLKVDSAFGDTWYDAK  885
            +++E P+ E++ +  +V D ME AV+L+VPL VD + G++WY+AK
Sbjct  836  IVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

302) polA in NC_019556


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  690 bits (2609),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 437/885 (50%), Positives = 644/885 (73%), Gaps = 20/885 (2%)

Query  12   NKLVLIDGNSIANRAFYAL----PLLNNDKGVYTNAVYGFAMMLMNVLEKEKPSHVLVAF  67
            NKL+LIDG+S+A RAF+AL      ++N+ G+ TNA+YGF +ML +++ + +P+HVLVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  68   DAGKTTFRHTTFKGYKGGRQKTPSELSEQFPFIRELLTAYDIPQYELANYEADDIIGTLT  127
            DAGKTTFR   + +YK+GR KTP E+ EQF++IRE+LTA +I+ YEL +YEADDIIGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  128  KKAEADGM--EVAIITGDRDLTQLASEKTTVYITKKGIADMETNTPETLKEKYNLTPEQI  185
            K AE   +  +V+I++GD+DL QL+ E+T V I+KKG+A+ E  TP  L EK  LTP+Q+
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  186  IDMKGLMGDSSDNIPGIPGVGEKTALKLLHEFGGTVESVLEHAEEISGkklkekvlenke  245
            ID+K+LMGD SDNIPG+  +GEKT+LKLLHEFG ++E++ EH + +   K+KE+++++++
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFG-SLEGIYEHIDGFKTSKMKENLINDRD  243

Query  246  lAILSKELATINVDSPIECTVESTKYDGYQTEKVIPLLKEMNFTTLLKNIEGDTPEETKE  305
             A+LSK LATIN  SPI   ++   Y+G +   +  +  EM+F  L K + ++ P+E   
Sbjct  244  QAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEPVA  303

Query  306  LKELSFEIVTELKEKHFGGKTALYVELENDNYHTANFIGLTVHSSQGTYFFTKETAESSE  365
            +  +S++ VT++    F++   +Y E   DNYH   +IG++   ++  Y  T  +  +++
Sbjct  304  V--ISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLATD  361

Query  366  VFRKWVESDQTKVVYDAKKTMVAMNRIGLAISGITFDIMLASYLLNPSDSIDDFTSVAIR  425
             F++    ++    YD K++ V ++++G+ + + ++D  LA+YLL+  +  ++++++A  
Sbjct  362  SFKQ--VFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NELSTIA--  416

Query  426  HDYTEV--ETDEAVYGKGAKRSTPEESIVAAHLARKAVAIADLEKRLVDDLEENEQLALM  483
            + +T++  E D++VYGKGAKR+ P+  ++  HLARK   + D   +++D L  +EQL L 
Sbjct  417  RIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLY  476

Query  484  EDLELPLTFVLAEMEMQGVSVDTERLENMKVELAGRLKTLEESIHSLAGEEFNINSPKQL  543
            +++ELPL+ VLA ME++G+ V+   L++M  +    + +L + I  +AG+EFNINSPKQL
Sbjct  477  QNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQL  536

Query  544  GVILFEKLGLP--AVKKTKTGYSTAADVLESLSGKHAIIDEILLYRQLGKIQSTYIEGLL  601
            G ILFEK+ LP    KKTKTGYSTA DVLE L+   +I+  IL YRQ+ K+QSTY+ GL 
Sbjct  537  GSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQ  596

Query  602  KVTDKETHKVHTRFNQTLTQTGRLSSVDPNLQNIPIRLEEGRKIRQVFVPSKPGWKMFSA  661
                 +  K+HTR+ Q LTQTGRLSSVDPNLQNIPIRLE+GR IR+ F PS  +  ++S+
Sbjct  597  DYILADG-KIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSS  655

Query  662  DYSQVELRVLAHISEDENLIYAFKHDYDIHTKTAMDVFHVEQD-EVDSLMRRQAKAVNFG  720
            DYSQ+ELRVLAHIS DE+LI AF+++ DIHT TAM VF +++  +V +  RR+AKAVNFG
Sbjct  656  DYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFG  715

Query  721  IVYGISDYGLSQNLGITRKEAKDFIDRYFVSYPAVKEYMQDIVRFAKEKGYVETILHRRR  780
            IVYGISD+GLS+NLGITRK++K +ID YF  YP++K YM+++VR AK+KGYVET++ RRR
Sbjct  716  IVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRR  775

Query  781  YIPEIVSRNFNVRGFAERTAMNTPIQGSAADIIKKAMILMSERLVSEKLEAKLLLQVHDE  840
             +P+I SRNFNVR+FAERTA+N+PIQGSAADI+K AMI +   L +  + AK+LLQVHDE
Sbjct  776  ELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDE  835

Query  841  LIFEAPEAEIAKLEEIVPDVMENAVELSVPLKVDSAFGDTWYDAK  885
            +++E P+ E++ +  +V D ME AV+L+VPL VD + G++WY+AK
Sbjct  836  IVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

303) polA in NC_018591


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  690 bits (2608),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 437/885 (50%), Positives = 644/885 (73%), Gaps = 20/885 (2%)

Query  12   NKLVLIDGNSIANRAFYAL----PLLNNDKGVYTNAVYGFAMMLMNVLEKEKPSHVLVAF  67
            NKL+LIDG+S+A RAF+AL      ++N+ G+ TNA+YGF +ML +++ + +P+HVLVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  68   DAGKTTFRHTTFKGYKGGRQKTPSELSEQFPFIRELLTAYDIPQYELANYEADDIIGTLT  127
            DAGKTTFR   + +YK+GR KTP E+ EQF++IRE+LTA +I+ YEL +YEADDIIGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  128  KKAEADGM--EVAIITGDRDLTQLASEKTTVYITKKGIADMETNTPETLKEKYNLTPQQI  185
            K AE   +  +V+I++GD+DL QL+ E+T V I+KKG+A+ E  TP  L EK  LTP+Q+
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  186  IDMKGLMGDSSDNIPGIPGVGEKTALKLLHEFGGTVESVLEHAEEISGkklkekvlenke  245
            ID+K+LMGD SDNIPG+  +GEKT+LKLLHEFG ++E++ EH + +   K+KE+++++++
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFG-SLEGIYEHIDGFKTSKMKENLINDRD  243

Query  246  lAILSKELATINVDSPIECTVESTKYDGYQTEKVIPLLKEMNFTTLLKNIEGDTPEETKE  305
             A+LSK LATIN  SPI   ++   Y+G +   +  +  EM+F  L K + ++ P+E   
Sbjct  244  QAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEPVA  303

Query  306  LKELSFEIVTELKEKHFGGKTALYVELENDNYHTANFIGLTVHSSQGTYFFTKETAESSE  365
            +  +S++ VT++    F++   +Y E   DNYH   +IG++   ++  Y  T  +  +++
Sbjct  304  V--ISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLATD  361

Query  366  VFRKWVESDQTKVVYDAKKTMVAMNRIGLAISGITFDIMLASYLLNPSDSIDDFTSVAIR  425
             F++    ++    YD K++ V ++++G+ + + ++D  LA+YLL+  +  ++++++A  
Sbjct  362  SFKQ--VFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NELSTIA--  416

Query  426  HDYTEV--ETDEAVYGKGAKRSTPEESIVAAHLARKAVAIADLEKRLVDDLEENEQLALM  483
            + +T++  E D++VYGKGAKR+ P+  ++  HLARK   + D   +++D L  +EQL L 
Sbjct  417  RIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLY  476

Query  484  EDLELPLTFVLAEMEMQGVSVDTERLENMKVELAGRLKTLEESIHSLAGEEFNINSPKQL  543
            +++ELPL+ VLA ME++G+ V+   L++M  +    + +L + I  +AG+EFNINSPKQL
Sbjct  477  QNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQL  536

Query  544  GVILFEKLGLP--AVKKTKTGYSTAADVLESLSGKHAIIDEILLYRQLGKIQSTYIEGLL  601
            G ILFEK+ LP    KKTKTGYSTA DVLE L+   +I+  IL YRQ+ K+QSTY+ GL 
Sbjct  537  GSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQ  596

Query  602  KVTDKETHKVHTRFNQTLTQTGRLSSVDPNLQNIPIRLEEGRKIRQVFVPSKPGWKMFSA  661
                 +  K+HTR+ Q LTQTGRLSSVDPNLQNIPIRLE+GR IR+ F PS  +  ++S+
Sbjct  597  DYILADG-KIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSS  655

Query  662  DYSQVELRVLAHISEDENLIYAFKHDYDIHTKTAMDVFHVEQD-EVDSLMRRQAKAVNFG  720
            DYSQ+ELRVLAHIS DE+LI AF+++ DIHT TAM VF +++  +V +  RR+AKAVNFG
Sbjct  656  DYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFG  715

Query  721  IVYGISDYGLSQNLGITRKEAKDFIDRYFVSYPAVKEYMQDIVRFAKEKGYVETILHRRR  780
            IVYGISD+GLS+NLGITRK++K +ID YF  YP++K YM+++VR AK+KGYVET++ RRR
Sbjct  716  IVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRR  775

Query  781  YIPEIVSRNFNVRGFAERTAMNTPIQGSAADIIKKAMILMSERLVSEKLEAKLLLQVHDE  840
             +P+I SRNFNVR+FAERTA+N+PIQGSAADI+K AMI +   L +  + AK+LLQVHDE
Sbjct  776  ELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDE  835

Query  841  LIFEAPEAEIAKLEEIVPDVMENAVELSVPLKVDSAFGDTWYDAK  885
            +++E P+ E++ +  +V D ME AV+L+VPL VD + G++WY+AK
Sbjct  836  IVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

304) polA in NC_018585


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  690 bits (2609),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 437/885 (50%), Positives = 644/885 (73%), Gaps = 20/885 (2%)

Query  12   NKLVLIDGNSIANRAFYAL----PLLNNDKGVYTNAVYGFAMMLMNVLEKEKPSHVLVAF  67
            NKL+LIDG+S+A RAF+AL      ++N+ G+ TNA+YGF +ML +++ + +P+HVLVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  68   DAGKTTFRHTTFKGYKGGRQKTPSELSEQFPFIRELLTAYDIPQYELANYEADDIIGTLT  127
            DAGKTTFR   + +YK+GR KTP E+ EQF++IRE+LTA +I+ YEL +YEADDIIGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  128  KKAEADGM--EVAIITGDRDLTQLASEKTTVYITKKGIADMETNTPETLKEKYNLTPEQI  185
            K AE   +  +V+I++GD+DL QL+ E+T V I+KKG+A+ E  TP  L EK  LTP+Q+
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  186  IDMKGLMGDSSDNIPGIPGVGEKTALKLLHEFGGTVESVLEHAEEISGkklkekvlenke  245
            ID+K+LMGD SDNIPG+  +GEKT+LKLLHEFG ++E++ EH + +   K+KE+++++++
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFG-SLEGIYEHIDGFKTSKMKENLINDRD  243

Query  246  lAILSKELATINVDSPIECTVESTKYDGYQTEKVIPLLKEMNFTTLLKNIEGDTPEETKE  305
             A+LSK LATIN  SPI   ++   Y+G +   +  +  EM+F  L K + ++ P+E   
Sbjct  244  QAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEPVA  303

Query  306  LKELSFEIVTELKEKHFGGKTALYVELENDNYHTANFIGLTVHSSQGTYFFTKETAESSE  365
            +  +S++ VT++    F++   +Y E   DNYH   +IG++   ++  Y  T  +  +++
Sbjct  304  V--ISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLATD  361

Query  366  VFRKWVESDQTKVVYDAKKTMVAMNRIGLAISGITFDIMLASYLLNPSDSIDDFTSVAIR  425
             F++    ++    YD K++ V ++++G+ + + ++D  LA+YLL+  +  ++++++A  
Sbjct  362  SFKQ--VFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NELSTIA--  416

Query  426  HDYTEV--ETDEAVYGKGAKRSTPEESIVAAHLARKAVAIADLEKRLVDDLEENEQLALM  483
            + +T++  E D++VYGKGAKR+ P+  ++  HLARK   + D   +++D L  +EQL L 
Sbjct  417  RIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLY  476

Query  484  EDLELPLTFVLAEMEMQGVSVDTERLENMKVELAGRLKTLEESIHSLAGEEFNINSPKQL  543
            +++ELPL+ VLA ME++G+ V+   L++M  +    + +L + I  +AG+EFNINSPKQL
Sbjct  477  QNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQL  536

Query  544  GVILFEKLGLP--AVKKTKTGYSTAADVLESLSGKHAIIDEILLYRQLGKIQSTYIEGLL  601
            G ILFEK+ LP    KKTKTGYSTA DVLE L+   +I+  IL YRQ+ K+QSTY+ GL 
Sbjct  537  GSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQ  596

Query  602  KVTDKETHKVHTRFNQTLTQTGRLSSVDPNLQNIPIRLEEGRKIRQVFVPSKPGWKMFSA  661
                 +  K+HTR+ Q LTQTGRLSSVDPNLQNIPIRLE+GR IR+ F PS  +  ++S+
Sbjct  597  DYILADG-KIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSS  655

Query  662  DYSQVELRVLAHISEDENLIYAFKHDYDIHTKTAMDVFHVEQD-EVDSLMRRQAKAVNFG  720
            DYSQ+ELRVLAHIS DE+LI AF+++ DIHT TAM VF +++  +V +  RR+AKAVNFG
Sbjct  656  DYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFG  715

Query  721  IVYGISDYGLSQNLGITRKEAKDFIDRYFVSYPAVKEYMQDIVRFAKEKGYVETILHRRR  780
            IVYGISD+GLS+NLGITRK++K +ID YF  YP++K YM+++VR AK+KGYVET++ RRR
Sbjct  716  IVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRR  775

Query  781  YIPEIVSRNFNVRGFAERTAMNTPIQGSAADIIKKAMILMSERLVSEKLEAKLLLQVHDE  840
             +P+I SRNFNVR+FAERTA+N+PIQGSAADI+K AMI +   L +  + AK+LLQVHDE
Sbjct  776  ELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDE  835

Query  841  LIFEAPEAEIAKLEEIVPDVMENAVELSVPLKVDSAFGDTWYDAK  885
            +++E P+ E++ +  +V D ME AV+L+VPL VD + G++WY+AK
Sbjct  836  IVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

305) M640_06800 in NC_021839


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  690 bits (2608),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 437/885 (50%), Positives = 644/885 (73%), Gaps = 20/885 (2%)

Query  12   NKLVLIDGNSIANRAFYAL----PLLNNDKGVYTNAVYGFAMMLMNVLEKEKPSHVLVAF  67
            NKL+LIDG+S+A RAF+AL      ++N+ G+ TNA+YGF +ML +++ + +P+HVLVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  68   DAGKTTFRHTTFKGYKGGRQKTPSELSEQFPFIRELLTAYDIPQYELANYEADDIIGTLT  127
            DAGKTTFR   + +YK+GR KTP E+ EQF++IRE+LTA +I+ YEL +YEADDIIGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  128  KKAEADGM--EVAIITGDRDLTQLASEKTTVYITKKGIADMETNTPETLKEKYNLTPQQI  185
            K AE   +  +V+I++GD+DL QL+ E+T V I+KKG+A+ E  TP  L EK  LTP+Q+
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  186  IDMKGLMGDSSDNIPGIPGVGEKTALKLLHEFGGTVESVLEHAEEISGkklkekvlenke  245
            ID+K+LMGD SDNIPG+  +GEKT+LKLLHEFG ++E++ EH + +   K+KE+++++++
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFG-SLEGIYEHIDGFKTSKMKENLINDRD  243

Query  246  lAILSKELATINVDSPIECTVESTKYDGYQTEKVIPLLKEMNFTTLLKNIEGDTPEETKE  305
             A+LSK LATIN  SPI   ++   Y+G +   +  +  EM+F  L K + ++ P+E   
Sbjct  244  QAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEPVA  303

Query  306  LKELSFEIVTELKEKHFGGKTALYVELENDNYHTANFIGLTVHSSQGTYFFTKETAESSE  365
            +  +S++ VT++    F++   +Y E   DNYH   +IG++   ++  Y  T  +  +++
Sbjct  304  V--ISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLATD  361

Query  366  VFRKWVESDQTKVVYDAKKTMVAMNRIGLAISGITFDIMLASYLLNPSDSIDDFTSVAIR  425
             F++    ++    YD K++ V ++++G+ + + ++D  LA+YLL+  +  ++++++A  
Sbjct  362  SFKQ--VFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NELSTIA--  416

Query  426  HDYTEV--ETDEAVYGKGAKRSTPEESIVAAHLARKAVAIADLEKRLVDDLEENEQLALM  483
            + +T++  E D++VYGKGAKR+ P+  ++  HLARK   + D   +++D L  +EQL L 
Sbjct  417  RIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLY  476

Query  484  EDLELPLTFVLAEMEMQGVSVDTERLENMKVELAGRLKTLEESIHSLAGEEFNINSPKQL  543
            +++ELPL+ VLA ME++G+ V+   L++M  +    + +L + I  +AG+EFNINSPKQL
Sbjct  477  QNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQL  536

Query  544  GVILFEKLGLP--AVKKTKTGYSTAADVLESLSGKHAIIDEILLYRQLGKIQSTYIEGLL  601
            G ILFEK+ LP    KKTKTGYSTA DVLE L+   +I+  IL YRQ+ K+QSTY+ GL 
Sbjct  537  GSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQ  596

Query  602  KVTDKETHKVHTRFNQTLTQTGRLSSVDPNLQNIPIRLEEGRKIRQVFVPSKPGWKMFSA  661
                 +  K+HTR+ Q LTQTGRLSSVDPNLQNIPIRLE+GR IR+ F PS  +  ++S+
Sbjct  597  DYILADG-KIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSS  655

Query  662  DYSQVELRVLAHISEDENLIYAFKHDYDIHTKTAMDVFHVEQD-EVDSLMRRQAKAVNFG  720
            DYSQ+ELRVLAHIS DE+LI AF+++ DIHT TAM VF +++  +V +  RR+AKAVNFG
Sbjct  656  DYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFG  715

Query  721  IVYGISDYGLSQNLGITRKEAKDFIDRYFVSYPAVKEYMQDIVRFAKEKGYVETILHRRR  780
            IVYGISD+GLS+NLGITRK++K +ID YF  YP++K YM+++VR AK+KGYVET++ RRR
Sbjct  716  IVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRR  775

Query  781  YIPEIVSRNFNVRGFAERTAMNTPIQGSAADIIKKAMILMSERLVSEKLEAKLLLQVHDE  840
             +P+I SRNFNVR+FAERTA+N+PIQGSAADI+K AMI +   L +  + AK+LLQVHDE
Sbjct  776  ELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDE  835

Query  841  LIFEAPEAEIAKLEEIVPDVMENAVELSVPLKVDSAFGDTWYDAK  885
            +++E P+ E++ +  +V D ME AV+L+VPL VD + G++WY+AK
Sbjct  836  IVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

306) M644_08125 in NC_021827


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  690 bits (2608),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 437/885 (50%), Positives = 644/885 (73%), Gaps = 20/885 (2%)

Query  12   NKLVLIDGNSIANRAFYAL----PLLNNDKGVYTNAVYGFAMMLMNVLEKEKPSHVLVAF  67
            NKL+LIDG+S+A RAF+AL      ++N+ G+ TNA+YGF +ML +++ + +P+HVLVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  68   DAGKTTFRHTTFKGYKGGRQKTPSELSEQFPFIRELLTAYDIPQYELANYEADDIIGTLT  127
            DAGKTTFR   + +YK+GR KTP E+ EQF++IRE+LTA +I+ YEL +YEADDIIGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  128  KKAEADGM--EVAIITGDRDLTQLASEKTTVYITKKGIADMETNTPETLKEKYNLTPQQI  185
            K AE   +  +V+I++GD+DL QL+ E+T V I+KKG+A+ E  TP  L EK  LTP+Q+
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  186  IDMKGLMGDSSDNIPGIPGVGEKTALKLLHEFGGTVESVLEHAEEISGkklkekvlenke  245
            ID+K+LMGD SDNIPG+  +GEKT+LKLLHEFG ++E++ EH + +   K+KE+++++++
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFG-SLEGIYEHIDGFKTSKMKENLINDRD  243

Query  246  lAILSKELATINVDSPIECTVESTKYDGYQTEKVIPLLKEMNFTTLLKNIEGDTPEETKE  305
             A+LSK LATIN  SPI   ++   Y+G +   +  +  EM+F  L K + ++ P+E   
Sbjct  244  QAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEPVA  303

Query  306  LKELSFEIVTELKEKHFGGKTALYVELENDNYHTANFIGLTVHSSQGTYFFTKETAESSE  365
            +  +S++ VT++    F++   +Y E   DNYH   +IG++   ++  Y  T  +  +++
Sbjct  304  V--ISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLATD  361

Query  366  VFRKWVESDQTKVVYDAKKTMVAMNRIGLAISGITFDIMLASYLLNPSDSIDDFTSVAIR  425
             F++    ++    YD K++ V ++++G+ + + ++D  LA+YLL+  +  ++++++A  
Sbjct  362  SFKQ--VFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NELSTIA--  416

Query  426  HDYTEV--ETDEAVYGKGAKRSTPEESIVAAHLARKAVAIADLEKRLVDDLEENEQLALM  483
            + +T++  E D++VYGKGAKR+ P+  ++  HLARK   + D   +++D L  +EQL L 
Sbjct  417  RIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLY  476

Query  484  EDLELPLTFVLAEMEMQGVSVDTERLENMKVELAGRLKTLEESIHSLAGEEFNINSPKQL  543
            +++ELPL+ VLA ME++G+ V+   L++M  +    + +L + I  +AG+EFNINSPKQL
Sbjct  477  QNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQL  536

Query  544  GVILFEKLGLP--AVKKTKTGYSTAADVLESLSGKHAIIDEILLYRQLGKIQSTYIEGLL  601
            G ILFEK+ LP    KKTKTGYSTA DVLE L+   +I+  IL YRQ+ K+QSTY+ GL 
Sbjct  537  GSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQ  596

Query  602  KVTDKETHKVHTRFNQTLTQTGRLSSVDPNLQNIPIRLEEGRKIRQVFVPSKPGWKMFSA  661
                 +  K+HTR+ Q LTQTGRLSSVDPNLQNIPIRLE+GR IR+ F PS  +  ++S+
Sbjct  597  DYILADG-KIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSS  655

Query  662  DYSQVELRVLAHISEDENLIYAFKHDYDIHTKTAMDVFHVEQD-EVDSLMRRQAKAVNFG  720
            DYSQ+ELRVLAHIS DE+LI AF+++ DIHT TAM VF +++  +V +  RR+AKAVNFG
Sbjct  656  DYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFG  715

Query  721  IVYGISDYGLSQNLGITRKEAKDFIDRYFVSYPAVKEYMQDIVRFAKEKGYVETILHRRR  780
            IVYGISD+GLS+NLGITRK++K +ID YF  YP++K YM+++VR AK+KGYVET++ RRR
Sbjct  716  IVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRR  775

Query  781  YIPEIVSRNFNVRGFAERTAMNTPIQGSAADIIKKAMILMSERLVSEKLEAKLLLQVHDE  840
             +P+I SRNFNVR+FAERTA+N+PIQGSAADI+K AMI +   L +  + AK+LLQVHDE
Sbjct  776  ELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDE  835

Query  841  LIFEAPEAEIAKLEEIVPDVMENAVELSVPLKVDSAFGDTWYDAK  885
            +++E P+ E++ +  +V D ME AV+L+VPL VD + G++WY+AK
Sbjct  836  IVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

307) M645_07335 in NC_021840


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  690 bits (2608),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 437/885 (50%), Positives = 644/885 (73%), Gaps = 20/885 (2%)

Query  12   NKLVLIDGNSIANRAFYAL----PLLNNDKGVYTNAVYGFAMMLMNVLEKEKPSHVLVAF  67
            NKL+LIDG+S+A RAF+AL      ++N+ G+ TNA+YGF +ML +++ + +P+HVLVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  68   DAGKTTFRHTTFKGYKGGRQKTPSELSEQFPFIRELLTAYDIPQYELANYEADDIIGTLT  127
            DAGKTTFR   + +YK+GR KTP E+ EQF++IRE+LTA +I+ YEL +YEADDIIGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  128  KKAEADGM--EVAIITGDRDLTQLASEKTTVYITKKGIADMETNTPETLKEKYNLTPQQI  185
            K AE   +  +V+I++GD+DL QL+ E+T V I+KKG+A+ E  TP  L EK  LTP+Q+
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  186  IDMKGLMGDSSDNIPGIPGVGEKTALKLLHEFGGTVESVLEHAEEISGkklkekvlenke  245
            ID+K+LMGD SDNIPG+  +GEKT+LKLLHEFG ++E++ EH + +   K+KE+++++++
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFG-SLEGIYEHIDGFKTSKMKENLINDRD  243

Query  246  lAILSKELATINVDSPIECTVESTKYDGYQTEKVIPLLKEMNFTTLLKNIEGDTPEETKE  305
             A+LSK LATIN  SPI   ++   Y+G +   +  +  EM+F  L K + ++ P+E   
Sbjct  244  QAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEPVA  303

Query  306  LKELSFEIVTELKEKHFGGKTALYVELENDNYHTANFIGLTVHSSQGTYFFTKETAESSE  365
            +  +S++ VT++    F++   +Y E   DNYH   +IG++   ++  Y  T  +  +++
Sbjct  304  V--ISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLATD  361

Query  366  VFRKWVESDQTKVVYDAKKTMVAMNRIGLAISGITFDIMLASYLLNPSDSIDDFTSVAIR  425
             F++    ++    YD K++ V ++++G+ + + ++D  LA+YLL+  +  ++++++A  
Sbjct  362  SFKQ--VFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NELSTIA--  416

Query  426  HDYTEV--ETDEAVYGKGAKRSTPEESIVAAHLARKAVAIADLEKRLVDDLEENEQLALM  483
            + +T++  E D++VYGKGAKR+ P+  ++  HLARK   + D   +++D L  +EQL L 
Sbjct  417  RIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLY  476

Query  484  EDLELPLTFVLAEMEMQGVSVDTERLENMKVELAGRLKTLEESIHSLAGEEFNINSPKQL  543
            +++ELPL+ VLA ME++G+ V+   L++M  +    + +L + I  +AG+EFNINSPKQL
Sbjct  477  QNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQL  536

Query  544  GVILFEKLGLP--AVKKTKTGYSTAADVLESLSGKHAIIDEILLYRQLGKIQSTYIEGLL  601
            G ILFEK+ LP    KKTKTGYSTA DVLE L+   +I+  IL YRQ+ K+QSTY+ GL 
Sbjct  537  GSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQ  596

Query  602  KVTDKETHKVHTRFNQTLTQTGRLSSVDPNLQNIPIRLEEGRKIRQVFVPSKPGWKMFSA  661
                 +  K+HTR+ Q LTQTGRLSSVDPNLQNIPIRLE+GR IR+ F PS  +  ++S+
Sbjct  597  DYILADG-KIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSS  655

Query  662  DYSQVELRVLAHISEDENLIYAFKHDYDIHTKTAMDVFHVEQD-EVDSLMRRQAKAVNFG  720
            DYSQ+ELRVLAHIS DE+LI AF+++ DIHT TAM VF +++  +V +  RR+AKAVNFG
Sbjct  656  DYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFG  715

Query  721  IVYGISDYGLSQNLGITRKEAKDFIDRYFVSYPAVKEYMQDIVRFAKEKGYVETILHRRR  780
            IVYGISD+GLS+NLGITRK++K +ID YF  YP++K YM+++VR AK+KGYVET++ RRR
Sbjct  716  IVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRR  775

Query  781  YIPEIVSRNFNVRGFAERTAMNTPIQGSAADIIKKAMILMSERLVSEKLEAKLLLQVHDE  840
             +P+I SRNFNVR+FAERTA+N+PIQGSAADI+K AMI +   L +  + AK+LLQVHDE
Sbjct  776  ELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDE  835

Query  841  LIFEAPEAEIAKLEEIVPDVMENAVELSVPLKVDSAFGDTWYDAK  885
            +++E P+ E++ +  +V D ME AV+L+VPL VD + G++WY+AK
Sbjct  836  IVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

308) M637_10810 in NC_021824


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  690 bits (2609),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 437/885 (50%), Positives = 644/885 (73%), Gaps = 20/885 (2%)

Query  12   NKLVLIDGNSIANRAFYAL----PLLNNDKGVYTNAVYGFAMMLMNVLEKEKPSHVLVAF  67
            NKL+LIDG+S+A RAF+AL      ++N+ G+ TNA+YGF +ML +++ + +P+HVLVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  68   DAGKTTFRHTTFKGYKGGRQKTPSELSEQFPFIRELLTAYDIPQYELANYEADDIIGTLT  127
            DAGKTTFR   + +YK+GR KTP E+ EQF++IRE+LTA +I+ YEL +YEADDIIGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  128  KKAEADGM--EVAIITGDRDLTQLASEKTTVYITKKGIADMETNTPETLKEKYNLTPEQI  185
            K AE   +  +V+I++GD+DL QL+ E+T V I+KKG+A+ E  TP  L EK  LTP+Q+
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  186  IDMKGLMGDSSDNIPGIPGVGEKTALKLLHEFGGTVESVLEHAEEISGkklkekvlenke  245
            ID+K+LMGD SDNIPG+  +GEKT+LKLLHEFG ++E++ EH + +   K+KE+++++++
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFG-SLEGIYEHIDGFKTSKMKENLINDRD  243

Query  246  lAILSKELATINVDSPIECTVESTKYDGYQTEKVIPLLKEMNFTTLLKNIEGDTPEETKE  305
             A+LSK LATIN  SPI   ++   Y+G +   +  +  EM+F  L K + ++ P+E   
Sbjct  244  QAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEPVA  303

Query  306  LKELSFEIVTELKEKHFGGKTALYVELENDNYHTANFIGLTVHSSQGTYFFTKETAESSE  365
            +  +S++ VT++    F++   +Y E   DNYH   +IG++   ++  Y  T  +  +++
Sbjct  304  V--ISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLATD  361

Query  366  VFRKWVESDQTKVVYDAKKTMVAMNRIGLAISGITFDIMLASYLLNPSDSIDDFTSVAIR  425
             F++    ++    YD K++ V ++++G+ + + ++D  LA+YLL+  +  ++++++A  
Sbjct  362  SFKQ--VFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NELSTIA--  416

Query  426  HDYTEV--ETDEAVYGKGAKRSTPEESIVAAHLARKAVAIADLEKRLVDDLEENEQLALM  483
            + +T++  E D++VYGKGAKR+ P+  ++  HLARK   + D   +++D L  +EQL L 
Sbjct  417  RIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLY  476

Query  484  EDLELPLTFVLAEMEMQGVSVDTERLENMKVELAGRLKTLEESIHSLAGEEFNINSPKQL  543
            +++ELPL+ VLA ME++G+ V+   L++M  +    + +L + I  +AG+EFNINSPKQL
Sbjct  477  QNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQL  536

Query  544  GVILFEKLGLP--AVKKTKTGYSTAADVLESLSGKHAIIDEILLYRQLGKIQSTYIEGLL  601
            G ILFEK+ LP    KKTKTGYSTA DVLE L+   +I+  IL YRQ+ K+QSTY+ GL 
Sbjct  537  GSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQ  596

Query  602  KVTDKETHKVHTRFNQTLTQTGRLSSVDPNLQNIPIRLEEGRKIRQVFVPSKPGWKMFSA  661
                 +  K+HTR+ Q LTQTGRLSSVDPNLQNIPIRLE+GR IR+ F PS  +  ++S+
Sbjct  597  DYILADG-KIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSS  655

Query  662  DYSQVELRVLAHISEDENLIYAFKHDYDIHTKTAMDVFHVEQD-EVDSLMRRQAKAVNFG  720
            DYSQ+ELRVLAHIS DE+LI AF+++ DIHT TAM VF +++  +V +  RR+AKAVNFG
Sbjct  656  DYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFG  715

Query  721  IVYGISDYGLSQNLGITRKEAKDFIDRYFVSYPAVKEYMQDIVRFAKEKGYVETILHRRR  780
            IVYGISD+GLS+NLGITRK++K +ID YF  YP++K YM+++VR AK+KGYVET++ RRR
Sbjct  716  IVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRR  775

Query  781  YIPEIVSRNFNVRGFAERTAMNTPIQGSAADIIKKAMILMSERLVSEKLEAKLLLQVHDE  840
             +P+I SRNFNVR+FAERTA+N+PIQGSAADI+K AMI +   L +  + AK+LLQVHDE
Sbjct  776  ELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDE  835

Query  841  LIFEAPEAEIAKLEEIVPDVMENAVELSVPLKVDSAFGDTWYDAK  885
            +++E P+ E++ +  +V D ME AV+L+VPL VD + G++WY+AK
Sbjct  836  IVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

309) M638_10545 in NC_021825


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  690 bits (2609),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 437/885 (50%), Positives = 644/885 (73%), Gaps = 20/885 (2%)

Query  12   NKLVLIDGNSIANRAFYAL----PLLNNDKGVYTNAVYGFAMMLMNVLEKEKPSHVLVAF  67
            NKL+LIDG+S+A RAF+AL      ++N+ G+ TNA+YGF +ML +++ + +P+HVLVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  68   DAGKTTFRHTTFKGYKGGRQKTPSELSEQFPFIRELLTAYDIPQYELANYEADDIIGTLT  127
            DAGKTTFR   + +YK+GR KTP E+ EQF++IRE+LTA +I+ YEL +YEADDIIGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  128  KKAEADGM--EVAIITGDRDLTQLASEKTTVYITKKGIADMETNTPETLKEKYNLTPEQI  185
            K AE   +  +V+I++GD+DL QL+ E+T V I+KKG+A+ E  TP  L EK  LTP+Q+
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  186  IDMKGLMGDSSDNIPGIPGVGEKTALKLLHEFGGTVESVLEHAEEISGkklkekvlenke  245
            ID+K+LMGD SDNIPG+  +GEKT+LKLLHEFG ++E++ EH + +   K+KE+++++++
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFG-SLEGIYEHIDGFKTSKMKENLINDRD  243

Query  246  lAILSKELATINVDSPIECTVESTKYDGYQTEKVIPLLKEMNFTTLLKNIEGDTPEETKE  305
             A+LSK LATIN  SPI   ++   Y+G +   +  +  EM+F  L K + ++ P+E   
Sbjct  244  QAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEPVA  303

Query  306  LKELSFEIVTELKEKHFGGKTALYVELENDNYHTANFIGLTVHSSQGTYFFTKETAESSE  365
            +  +S++ VT++    F++   +Y E   DNYH   +IG++   ++  Y  T  +  +++
Sbjct  304  V--ISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLATD  361

Query  366  VFRKWVESDQTKVVYDAKKTMVAMNRIGLAISGITFDIMLASYLLNPSDSIDDFTSVAIR  425
             F++    ++    YD K++ V ++++G+ + + ++D  LA+YLL+  +  ++++++A  
Sbjct  362  SFKQ--VFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NELSTIA--  416

Query  426  HDYTEV--ETDEAVYGKGAKRSTPEESIVAAHLARKAVAIADLEKRLVDDLEENEQLALM  483
            + +T++  E D++VYGKGAKR+ P+  ++  HLARK   + D   +++D L  +EQL L 
Sbjct  417  RIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLY  476

Query  484  EDLELPLTFVLAEMEMQGVSVDTERLENMKVELAGRLKTLEESIHSLAGEEFNINSPKQL  543
            +++ELPL+ VLA ME++G+ V+   L++M  +    + +L + I  +AG+EFNINSPKQL
Sbjct  477  QNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQL  536

Query  544  GVILFEKLGLP--AVKKTKTGYSTAADVLESLSGKHAIIDEILLYRQLGKIQSTYIEGLL  601
            G ILFEK+ LP    KKTKTGYSTA DVLE L+   +I+  IL YRQ+ K+QSTY+ GL 
Sbjct  537  GSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQ  596

Query  602  KVTDKETHKVHTRFNQTLTQTGRLSSVDPNLQNIPIRLEEGRKIRQVFVPSKPGWKMFSA  661
                 +  K+HTR+ Q LTQTGRLSSVDPNLQNIPIRLE+GR IR+ F PS  +  ++S+
Sbjct  597  DYILADG-KIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSS  655

Query  662  DYSQVELRVLAHISEDENLIYAFKHDYDIHTKTAMDVFHVEQD-EVDSLMRRQAKAVNFG  720
            DYSQ+ELRVLAHIS DE+LI AF+++ DIHT TAM VF +++  +V +  RR+AKAVNFG
Sbjct  656  DYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFG  715

Query  721  IVYGISDYGLSQNLGITRKEAKDFIDRYFVSYPAVKEYMQDIVRFAKEKGYVETILHRRR  780
            IVYGISD+GLS+NLGITRK++K +ID YF  YP++K YM+++VR AK+KGYVET++ RRR
Sbjct  716  IVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRR  775

Query  781  YIPEIVSRNFNVRGFAERTAMNTPIQGSAADIIKKAMILMSERLVSEKLEAKLLLQVHDE  840
             +P+I SRNFNVR+FAERTA+N+PIQGSAADI+K AMI +   L +  + AK+LLQVHDE
Sbjct  776  ELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDE  835

Query  841  LIFEAPEAEIAKLEEIVPDVMENAVELSVPLKVDSAFGDTWYDAK  885
            +++E P+ E++ +  +V D ME AV+L+VPL VD + G++WY+AK
Sbjct  836  IVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

310) M643_02315 in NC_021826


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  690 bits (2608),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 437/885 (50%), Positives = 644/885 (73%), Gaps = 20/885 (2%)

Query  12   NKLVLIDGNSIANRAFYAL----PLLNNDKGVYTNAVYGFAMMLMNVLEKEKPSHVLVAF  67
            NKL+LIDG+S+A RAF+AL      ++N+ G+ TNA+YGF +ML +++ + +P+HVLVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  68   DAGKTTFRHTTFKGYKGGRQKTPSELSEQFPFIRELLTAYDIPQYELANYEADDIIGTLT  127
            DAGKTTFR   + +YK+GR KTP E+ EQF++IRE+LTA +I+ YEL +YEADDIIGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  128  KKAEADGM--EVAIITGDRDLTQLASEKTTVYITKKGIADMETNTPETLKEKYNLTPQQI  185
            K AE   +  +V+I++GD+DL QL+ E+T V I+KKG+A+ E  TP  L EK  LTP+Q+
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  186  IDMKGLMGDSSDNIPGIPGVGEKTALKLLHEFGGTVESVLEHAEEISGkklkekvlenke  245
            ID+K+LMGD SDNIPG+  +GEKT+LKLLHEFG ++E++ EH + +   K+KE+++++++
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFG-SLEGIYEHIDGFKTSKMKENLINDRD  243

Query  246  lAILSKELATINVDSPIECTVESTKYDGYQTEKVIPLLKEMNFTTLLKNIEGDTPEETKE  305
             A+LSK LATIN  SPI   ++   Y+G +   +  +  EM+F  L K + ++ P+E   
Sbjct  244  QAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEPVA  303

Query  306  LKELSFEIVTELKEKHFGGKTALYVELENDNYHTANFIGLTVHSSQGTYFFTKETAESSE  365
            +  +S++ VT++    F++   +Y E   DNYH   +IG++   ++  Y  T  +  +++
Sbjct  304  V--ISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLATD  361

Query  366  VFRKWVESDQTKVVYDAKKTMVAMNRIGLAISGITFDIMLASYLLNPSDSIDDFTSVAIR  425
             F++    ++    YD K++ V ++++G+ + + ++D  LA+YLL+  +  ++++++A  
Sbjct  362  SFKQ--VFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NELSTIA--  416

Query  426  HDYTEV--ETDEAVYGKGAKRSTPEESIVAAHLARKAVAIADLEKRLVDDLEENEQLALM  483
            + +T++  E D++VYGKGAKR+ P+  ++  HLARK   + D   +++D L  +EQL L 
Sbjct  417  RIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLY  476

Query  484  EDLELPLTFVLAEMEMQGVSVDTERLENMKVELAGRLKTLEESIHSLAGEEFNINSPKQL  543
            +++ELPL+ VLA ME++G+ V+   L++M  +    + +L + I  +AG+EFNINSPKQL
Sbjct  477  QNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQL  536

Query  544  GVILFEKLGLP--AVKKTKTGYSTAADVLESLSGKHAIIDEILLYRQLGKIQSTYIEGLL  601
            G ILFEK+ LP    KKTKTGYSTA DVLE L+   +I+  IL YRQ+ K+QSTY+ GL 
Sbjct  537  GSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQ  596

Query  602  KVTDKETHKVHTRFNQTLTQTGRLSSVDPNLQNIPIRLEEGRKIRQVFVPSKPGWKMFSA  661
                 +  K+HTR+ Q LTQTGRLSSVDPNLQNIPIRLE+GR IR+ F PS  +  ++S+
Sbjct  597  DYILADG-KIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSS  655

Query  662  DYSQVELRVLAHISEDENLIYAFKHDYDIHTKTAMDVFHVEQD-EVDSLMRRQAKAVNFG  720
            DYSQ+ELRVLAHIS DE+LI AF+++ DIHT TAM VF +++  +V +  RR+AKAVNFG
Sbjct  656  DYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFG  715

Query  721  IVYGISDYGLSQNLGITRKEAKDFIDRYFVSYPAVKEYMQDIVRFAKEKGYVETILHRRR  780
            IVYGISD+GLS+NLGITRK++K +ID YF  YP++K YM+++VR AK+KGYVET++ RRR
Sbjct  716  IVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRR  775

Query  781  YIPEIVSRNFNVRGFAERTAMNTPIQGSAADIIKKAMILMSERLVSEKLEAKLLLQVHDE  840
             +P+I SRNFNVR+FAERTA+N+PIQGSAADI+K AMI +   L +  + AK+LLQVHDE
Sbjct  776  ELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDE  835

Query  841  LIFEAPEAEIAKLEEIVPDVMENAVELSVPLKVDSAFGDTWYDAK  885
            +++E P+ E++ +  +V D ME AV+L+VPL VD + G++WY+AK
Sbjct  836  IVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

311) M641_05650 in NC_021838


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  690 bits (2608),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 437/885 (50%), Positives = 644/885 (73%), Gaps = 20/885 (2%)

Query  12   NKLVLIDGNSIANRAFYAL----PLLNNDKGVYTNAVYGFAMMLMNVLEKEKPSHVLVAF  67
            NKL+LIDG+S+A RAF+AL      ++N+ G+ TNA+YGF +ML +++ + +P+HVLVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  68   DAGKTTFRHTTFKGYKGGRQKTPSELSEQFPFIRELLTAYDIPQYELANYEADDIIGTLT  127
            DAGKTTFR   + +YK+GR KTP E+ EQF++IRE+LTA +I+ YEL +YEADDIIGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  128  KKAEADGM--EVAIITGDRDLTQLASEKTTVYITKKGIADMETNTPETLKEKYNLTPQQI  185
            K AE   +  +V+I++GD+DL QL+ E+T V I+KKG+A+ E  TP  L EK  LTP+Q+
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  186  IDMKGLMGDSSDNIPGIPGVGEKTALKLLHEFGGTVESVLEHAEEISGkklkekvlenke  245
            ID+K+LMGD SDNIPG+  +GEKT+LKLLHEFG ++E++ EH + +   K+KE+++++++
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFG-SLEGIYEHIDGFKTSKMKENLINDRD  243

Query  246  lAILSKELATINVDSPIECTVESTKYDGYQTEKVIPLLKEMNFTTLLKNIEGDTPEETKE  305
             A+LSK LATIN  SPI   ++   Y+G +   +  +  EM+F  L K + ++ P+E   
Sbjct  244  QAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEPVA  303

Query  306  LKELSFEIVTELKEKHFGGKTALYVELENDNYHTANFIGLTVHSSQGTYFFTKETAESSE  365
            +  +S++ VT++    F++   +Y E   DNYH   +IG++   ++  Y  T  +  +++
Sbjct  304  V--ISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLATD  361

Query  366  VFRKWVESDQTKVVYDAKKTMVAMNRIGLAISGITFDIMLASYLLNPSDSIDDFTSVAIR  425
             F++    ++    YD K++ V ++++G+ + + ++D  LA+YLL+  +  ++++++A  
Sbjct  362  SFKQ--VFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NELSTIA--  416

Query  426  HDYTEV--ETDEAVYGKGAKRSTPEESIVAAHLARKAVAIADLEKRLVDDLEENEQLALM  483
            + +T++  E D++VYGKGAKR+ P+  ++  HLARK   + D   +++D L  +EQL L 
Sbjct  417  RIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLY  476

Query  484  EDLELPLTFVLAEMEMQGVSVDTERLENMKVELAGRLKTLEESIHSLAGEEFNINSPKQL  543
            +++ELPL+ VLA ME++G+ V+   L++M  +    + +L + I  +AG+EFNINSPKQL
Sbjct  477  QNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQL  536

Query  544  GVILFEKLGLP--AVKKTKTGYSTAADVLESLSGKHAIIDEILLYRQLGKIQSTYIEGLL  601
            G ILFEK+ LP    KKTKTGYSTA DVLE L+   +I+  IL YRQ+ K+QSTY+ GL 
Sbjct  537  GSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQ  596

Query  602  KVTDKETHKVHTRFNQTLTQTGRLSSVDPNLQNIPIRLEEGRKIRQVFVPSKPGWKMFSA  661
                 +  K+HTR+ Q LTQTGRLSSVDPNLQNIPIRLE+GR IR+ F PS  +  ++S+
Sbjct  597  DYILADG-KIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSS  655

Query  662  DYSQVELRVLAHISEDENLIYAFKHDYDIHTKTAMDVFHVEQD-EVDSLMRRQAKAVNFG  720
            DYSQ+ELRVLAHIS DE+LI AF+++ DIHT TAM VF +++  +V +  RR+AKAVNFG
Sbjct  656  DYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFG  715

Query  721  IVYGISDYGLSQNLGITRKEAKDFIDRYFVSYPAVKEYMQDIVRFAKEKGYVETILHRRR  780
            IVYGISD+GLS+NLGITRK++K +ID YF  YP++K YM+++VR AK+KGYVET++ RRR
Sbjct  716  IVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRR  775

Query  781  YIPEIVSRNFNVRGFAERTAMNTPIQGSAADIIKKAMILMSERLVSEKLEAKLLLQVHDE  840
             +P+I SRNFNVR+FAERTA+N+PIQGSAADI+K AMI +   L +  + AK+LLQVHDE
Sbjct  776  ELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDE  835

Query  841  LIFEAPEAEIAKLEEIVPDVMENAVELSVPLKVDSAFGDTWYDAK  885
            +++E P+ E++ +  +V D ME AV+L+VPL VD + G++WY+AK
Sbjct  836  IVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

312) MUO_08055 in NC_017728


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  689 bits (2607),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 437/885 (50%), Positives = 644/885 (73%), Gaps = 20/885 (2%)

Query  2    NKLVLIDGNSIANRAFYAL----PLLNNDKGVYTNAVYGFAMMLMNVLEKEKPSHVLVAF  57
            NKL+LIDG+S+A RAF+AL      ++N+ G+ TNA+YGF +ML +++ + +P+HVLVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  58   DAGKTTFRHTTFKGYKGGRQKTPSELSEQFPFIRELLTAYDIPQYELANYEADDIIGTLT  117
            DAGKTTFR   + +YK+GR KTP E+ EQF++IRE+LTA +I+ YEL +YEADDIIGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  118  KKAEADGM--EVAIITGDRDLTQLASEKTTVYITKKGIADMETNTPETLKEKYNLTPQQI  175
            K AE   +  +V+I++GD+DL QL+ E+T V I+KKG+A+ E  TP  L EK  LTP+Q+
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  176  IDMKGLMGDSSDNIPGIPGVGEKTALKLLHEFGGTVESVLEHAEEISGkklkekvlenke  235
            ID+K+LMGD SDNIPG+  +GEKT+LKLLHEFG ++E++ EH + +   K+KE+++++++
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFG-SLEGIYEHIDGFKTSKMKENLINDRD  243

Query  236  lAILSKELATINVDSPIECTVESTKYDGYQTEKVIPLLKEMNFTTLLKNIEGDTPEETKE  295
             A+LSK LATIN  SPI   ++   Y+G +   +  +  EM+F  L K + ++ P+E   
Sbjct  244  QAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEPVA  303

Query  296  LKELSFEIVTELKEKHFGGKTALYVELENDNYHTANFIGLTVHSSQGTYFFTKETAESSE  355
            +  +S++ VT++    F++   +Y E   DNYH   +IG++   ++  Y  T  +  +++
Sbjct  304  V--ISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLATD  361

Query  356  VFRKWVESDQTKVVYDAKKTMVAMNRIGLAISGITFDIMLASYLLNPSDSIDDFTSVAIR  415
             F++    ++    YD K++ V ++++G+ + + ++D  LA+YLL+  +  ++++++A  
Sbjct  362  SFKQ--VFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NELSTIA--  416

Query  416  HDYTEV--ETDEAVYGKGAKRSTPEESIVAAHLARKAVAIADLEKRLVDDLEENEQLALM  473
            + +T++  E D++VYGKGAKR+ P+  ++  HLARK   + D   +++D L  +EQL L 
Sbjct  417  RIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLY  476

Query  474  EDLELPLTFVLAEMEMQGVSVDTERLENMKVELAGRLKTLEESIHSLAGEEFNINSPKQL  533
            +++ELPL+ VLA ME++G+ V+   L++M  +    + +L + I  +AG+EFNINSPKQL
Sbjct  477  QNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQL  536

Query  534  GVILFEKLGLP--AVKKTKTGYSTAADVLESLSGKHAIIDEILLYRQLGKIQSTYIEGLL  591
            G ILFEK+ LP    KKTKTGYSTA DVLE L+   +I+  IL YRQ+ K+QSTY+ GL 
Sbjct  537  GSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQ  596

Query  592  KVTDKETHKVHTRFNQTLTQTGRLSSVDPNLQNIPIRLEEGRKIRQVFVPSKPGWKMFSA  651
                 +  K+HTR+ Q LTQTGRLSSVDPNLQNIPIRLE+GR IR+ F PS  +  ++S+
Sbjct  597  DYILADG-KIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSS  655

Query  652  DYSQVELRVLAHISEDENLIYAFKHDYDIHTKTAMDVFHVEQD-EVDSLMRRQAKAVNFG  710
            DYSQ+ELRVLAHIS DE+LI AF+++ DIHT TAM VF +++  +V +  RR+AKAVNFG
Sbjct  656  DYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFG  715

Query  711  IVYGISDYGLSQNLGITRKEAKDFIDRYFVSYPAVKEYMQDIVRFAKEKGYVETILHRRR  770
            IVYGISD+GLS+NLGITRK++K +ID YF  YP++K YM+++VR AK+KGYVET++ RRR
Sbjct  716  IVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRR  775

Query  771  YIPEIVSRNFNVRGFAERTAMNTPIQGSAADIIKKAMILMSERLVSEKLEAKLLLQVHDE  830
             +P+I SRNFNVR+FAERTA+N+PIQGSAADI+K AMI +   L +  + AK+LLQVHDE
Sbjct  776  ELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDE  835

Query  831  LIFEAPEAEIAKLEEIVPDVMENAVELSVPLKVDSAFGDTWYDAK  875
            +++E P+ E++ +  +V D ME AV+L+VPL VD + G++WY+AK
Sbjct  836  IVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

313) polA in NC_012488


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  689 bits (2607),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 437/885 (50%), Positives = 644/885 (73%), Gaps = 20/885 (2%)

Query  2    NKLVLIDGNSIANRAFYAL----PLLNNDKGVYTNAVYGFAMMLMNVLEKEKPSHVLVAF  57
            NKL+LIDG+S+A RAF+AL      ++N+ G+ TNA+YGF +ML +++ + +P+HVLVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  58   DAGKTTFRHTTFKGYKGGRQKTPSELSEQFPFIRELLTAYDIPQYELANYEADDIIGTLT  117
            DAGKTTFR   + +YK+GR KTP E+ EQF++IRE+LTA +I+ YEL +YEADDIIGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  118  KKAEADGM--EVAIITGDRDLTQLASEKTTVYITKKGIADMETNTPETLKEKYNLTPQQI  175
            K AE   +  +V+I++GD+DL QL+ E+T V I+KKG+A+ E  TP  L EK  LTP+Q+
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  176  IDMKGLMGDSSDNIPGIPGVGEKTALKLLHEFGGTVESVLEHAEEISGkklkekvlenke  235
            ID+K+LMGD SDNIPG+  +GEKT+LKLLHEFG ++E++ EH + +   K+KE+++++++
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFG-SLEGIYEHIDGFKTSKMKENLINDRD  243

Query  236  lAILSKELATINVDSPIECTVESTKYDGYQTEKVIPLLKEMNFTTLLKNIEGDTPEETKE  295
             A+LSK LATIN  SPI   ++   Y+G +   +  +  EM+F  L K + ++ P+E   
Sbjct  244  QAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEPVA  303

Query  296  LKELSFEIVTELKEKHFGGKTALYVELENDNYHTANFIGLTVHSSQGTYFFTKETAESSE  355
            +  +S++ VT++    F++   +Y E   DNYH   +IG++   ++  Y  T  +  +++
Sbjct  304  V--ISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLATD  361

Query  356  VFRKWVESDQTKVVYDAKKTMVAMNRIGLAISGITFDIMLASYLLNPSDSIDDFTSVAIR  415
             F++    ++    YD K++ V ++++G+ + + ++D  LA+YLL+  +  ++++++A  
Sbjct  362  SFKQ--VFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NELSTIA--  416

Query  416  HDYTEV--ETDEAVYGKGAKRSTPEESIVAAHLARKAVAIADLEKRLVDDLEENEQLALM  473
            + +T++  E D++VYGKGAKR+ P+  ++  HLARK   + D   +++D L  +EQL L 
Sbjct  417  RIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLY  476

Query  474  EDLELPLTFVLAEMEMQGVSVDTERLENMKVELAGRLKTLEESIHSLAGEEFNINSPKQL  533
            +++ELPL+ VLA ME++G+ V+   L++M  +    + +L + I  +AG+EFNINSPKQL
Sbjct  477  QNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQL  536

Query  534  GVILFEKLGLP--AVKKTKTGYSTAADVLESLSGKHAIIDEILLYRQLGKIQSTYIEGLL  591
            G ILFEK+ LP    KKTKTGYSTA DVLE L+   +I+  IL YRQ+ K+QSTY+ GL 
Sbjct  537  GSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQ  596

Query  592  KVTDKETHKVHTRFNQTLTQTGRLSSVDPNLQNIPIRLEEGRKIRQVFVPSKPGWKMFSA  651
                 +  K+HTR+ Q LTQTGRLSSVDPNLQNIPIRLE+GR IR+ F PS  +  ++S+
Sbjct  597  DYILADG-KIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSS  655

Query  652  DYSQVELRVLAHISEDENLIYAFKHDYDIHTKTAMDVFHVEQD-EVDSLMRRQAKAVNFG  710
            DYSQ+ELRVLAHIS DE+LI AF+++ DIHT TAM VF +++  +V +  RR+AKAVNFG
Sbjct  656  DYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFG  715

Query  711  IVYGISDYGLSQNLGITRKEAKDFIDRYFVSYPAVKEYMQDIVRFAKEKGYVETILHRRR  770
            IVYGISD+GLS+NLGITRK++K +ID YF  YP++K YM+++VR AK+KGYVET++ RRR
Sbjct  716  IVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRR  775

Query  771  YIPEIVSRNFNVRGFAERTAMNTPIQGSAADIIKKAMILMSERLVSEKLEAKLLLQVHDE  830
             +P+I SRNFNVR+FAERTA+N+PIQGSAADI+K AMI +   L +  + AK+LLQVHDE
Sbjct  776  ELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDE  835

Query  831  LIFEAPEAEIAKLEEIVPDVMENAVELSVPLKVDSAFGDTWYDAK  875
            +++E P+ E++ +  +V D ME AV+L+VPL VD + G++WY+AK
Sbjct  836  IVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

314) polA in NC_011660


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  689 bits (2606),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 435/885 (50%), Positives = 643/885 (73%), Gaps = 20/885 (2%)

Query  2    NKLVLIDGNSIANRAFYAL----PLLNNDKGVYTNAVYGFAMMLMNVLEKEKPSHVLVAF  57
            NKL+LIDG+S+A RAF+AL      ++N+ G+ TNA+YGF +ML +++ + +P+HVLVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  58   DAGKTTFRHTTFKGYKGGRQKTPSELSEQFPFIRELLTAYDIPQYELANYEADDIIGTLT  117
            DAGKTTFR   + +YK+GR KTP E+ EQF++IRE+LTA +I+ YEL +YEADDIIGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  118  KKAEADGM--EVAIITGDRDLTQLASEKTTVYITKKGIADMETNTPETLKEKYNLTPEQI  175
            K AE   +  +V+I++GD+DL QL+ E+T V I+KKG+A+ E  TP  L EK  LTP+Q+
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  176  IDMKGLMGDSSDNIPGIPGVGEKTALKLLHEFGGTVESVLEHAEEISGkklkekvlenke  235
            ID+K+LMGD SDNIPG+  +GEKT+LKLLHEFG ++E++ EH + +   K+KE+++++++
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFG-SLEGIYEHIDGFKTSKMKENLINDRD  243

Query  236  lAILSKELATINVDSPIECTVESTKYDGYQTEKVIPLLKEMNFTTLLKNIEGDTPEEAKE  295
             A+LSK LATIN  SPI   ++   Y+G +   +  +  EM+F  L K + ++ P+E+  
Sbjct  244  QAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEPVA  303

Query  296  LKELSFEIVTELKEKHFGGKTALYVELENDNYHTSNFIGLTVHSSQGTYFFTKETAENSE  355
            +  +S++ VT++    F++   +Y E   DNYH   +IG++   ++  Y  T  +   ++
Sbjct  304  V--ISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLATD  361

Query  356  AFREWVESEQTKVVYDAKKTMVAMNRIGLAISGITFDIMLASYLLNPSDSIDDFTSVAVR  415
            +F++    ++    YD K++ V ++++G+ + + ++D  LA+YLL+  +  ++++++A  
Sbjct  362  SFKQ--VFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NELSTIA--  416

Query  416  HDYTEV--ETDEAVYGKGAKRSTPEESIVASHLARKAVAIADLEKRLVADLEENEQLALM  473
            + +T++  E D++VYGKGAKR+ P+  ++  HLARK   + D   +++  L  +EQL L 
Sbjct  417  RIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLY  476

Query  474  EDLELPLTFVLAEMEMQGVSVDTERLENMKVELAGRLKTLEESIHSLAGEAFNINSPKQL  533
            +++ELPL+ VLA ME++G+ V+   L++M  +    + +L + I  +AG+ FNINSPKQL
Sbjct  477  QNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQL  536

Query  534  GVILFEKLGLP--AVKKTKTGYSTAADVLESLSGKHAIIDEILLYRQLGKIQSTYIEGLL  591
            G ILFEK+ LP    KKTKTGYSTA DVLE L+   +I+  IL YRQ+ K+QSTY+ GL 
Sbjct  537  GSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQ  596

Query  592  KVTDKETHKVHTRFNQTLTQTGRLSSVDPNLQNIPIRLEEGRKIRQVFVPSKPGWKMFSA  651
                 +  K+HTR+ Q LTQTGRLSSVDPNLQNIPIRLE+GR IR+ F PS  +  ++S+
Sbjct  597  DYILADG-KIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSS  655

Query  652  DYSQVELRVLAHISEDENLIYAFKHDYDIHTKTAMDVFHVEQD-EVDSLMRRQAKAVNFG  710
            DYSQ+ELRVLAHIS DE+LI AF+++ DIHT TAM VF +++  +V +  RR+AKAVNFG
Sbjct  656  DYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFG  715

Query  711  IVYGISDYGLSQNLGITRKEAKDFIDRYFVSYPAVKEYMQDIVRFAKEKGYVETILHRRR  770
            IVYGISD+GLS+NLGITRK++K +ID YF  YP++K YM+++VR AK+KGYVET++ RRR
Sbjct  716  IVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRR  775

Query  771  YIPEIVSRNFNVRGFAERTAMNTPIQGSAADIIKKAMILMSERLVSEKLEAKLLLQVHDE  830
             +P+I SRNFNVR+FAERTA+N+PIQGSAADI+K AMI +   L +  + AK+LLQVHDE
Sbjct  776  ELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDE  835

Query  831  LIFEAPEAEIAKLEEIVPDVMENAVELSVPLKVDSAFGDTWYDAK  875
            +++E P+ E++ +  +V D ME AV+L+VPL VD + G++WY+AK
Sbjct  836  IVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

315) polA in NC_017537


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  689 bits (2606),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 435/885 (50%), Positives = 643/885 (73%), Gaps = 20/885 (2%)

Query  2    NKLVLIDGNSIANRAFYAL----PLLNNDKGVYTNAVYGFAMMLMNVLEKEKPSHVLVAF  57
            NKL+LIDG+S+A RAF+AL      ++N+ G+ TNA+YGF +ML +++ + +P+HVLVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  58   DAGKTTFRHTTFKGYKGGRQKTPSELSEQFPFIRELLTAYDIPQYELANYEADDIIGTLT  117
            DAGKTTFR   + +YK+GR KTP E+ EQF++IRE+LTA +I+ YEL +YEADDIIGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  118  KKAEADGM--EVAIITGDRDLTQLASEKTTVYITKKGIADMETNTPETLKEKYNLTPEQI  175
            K AE   +  +V+I++GD+DL QL+ E+T V I+KKG+A+ E  TP  L EK  LTP+Q+
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  176  IDMKGLMGDSSDNIPGIPGVGEKTALKLLHEFGGTVESVLEHAEEISGkklkekvlenke  235
            ID+K+LMGD SDNIPG+  +GEKT+LKLLHEFG ++E++ EH + +   K+KE+++++++
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFG-SLEGIYEHIDGFKTSKMKENLINDRD  243

Query  236  lAILSKELATINVDSPIECTVESTKYDGYQTEKVIPLLKEMNFTTLLKNIEGDTPEEAKE  295
             A+LSK LATIN  SPI   ++   Y+G +   +  +  EM+F  L K + ++ P+E+  
Sbjct  244  QAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEPVA  303

Query  296  LKELSFEIVTELKEKHFGGKTALYVELENDNYHTSNFIGLTVHSSQGTYFFTKETAENSE  355
            +  +S++ VT++    F++   +Y E   DNYH   +IG++   ++  Y  T  +   ++
Sbjct  304  V--ISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLATD  361

Query  356  AFREWVESEQTKVVYDAKKTMVAMNRIGLAISGITFDIMLASYLLNPSDSIDDFTSVAVR  415
            +F++    ++    YD K++ V ++++G+ + + ++D  LA+YLL+  +  ++++++A  
Sbjct  362  SFKQ--VFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NELSTIA--  416

Query  416  HDYTEV--ETDEAVYGKGAKRSTPEESIVASHLARKAVAIADLEKRLVADLEENEQLALM  473
            + +T++  E D++VYGKGAKR+ P+  ++  HLARK   + D   +++  L  +EQL L 
Sbjct  417  RIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLY  476

Query  474  EDLELPLTFVLAEMEMQGVSVDTERLENMKVELAGRLKTLEESIHSLAGEAFNINSPKQL  533
            +++ELPL+ VLA ME++G+ V+   L++M  +    + +L + I  +AG+ FNINSPKQL
Sbjct  477  QNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQL  536

Query  534  GVILFEKLGLP--AVKKTKTGYSTAADVLESLSGKHAIIDEILLYRQLGKIQSTYIEGLL  591
            G ILFEK+ LP    KKTKTGYSTA DVLE L+   +I+  IL YRQ+ K+QSTY+ GL 
Sbjct  537  GSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQ  596

Query  592  KVTDKETHKVHTRFNQTLTQTGRLSSVDPNLQNIPIRLEEGRKIRQVFVPSKPGWKMFSA  651
                 +  K+HTR+ Q LTQTGRLSSVDPNLQNIPIRLE+GR IR+ F PS  +  ++S+
Sbjct  597  DYILADG-KIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSS  655

Query  652  DYSQVELRVLAHISEDENLIYAFKHDYDIHTKTAMDVFHVEQD-EVDSLMRRQAKAVNFG  710
            DYSQ+ELRVLAHIS DE+LI AF+++ DIHT TAM VF +++  +V +  RR+AKAVNFG
Sbjct  656  DYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFG  715

Query  711  IVYGISDYGLSQNLGITRKEAKDFIDRYFVSYPAVKEYMQDIVRFAKEKGYVETILHRRR  770
            IVYGISD+GLS+NLGITRK++K +ID YF  YP++K YM+++VR AK+KGYVET++ RRR
Sbjct  716  IVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRR  775

Query  771  YIPEIVSRNFNVRGFAERTAMNTPIQGSAADIIKKAMILMSERLVSEKLEAKLLLQVHDE  830
             +P+I SRNFNVR+FAERTA+N+PIQGSAADI+K AMI +   L +  + AK+LLQVHDE
Sbjct  776  ELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDE  835

Query  831  LIFEAPEAEIAKLEEIVPDVMENAVELSVPLKVDSAFGDTWYDAK  875
            +++E P+ E++ +  +V D ME AV+L+VPL VD + G++WY+AK
Sbjct  836  IVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

316) polA in NC_002973


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  689 bits (2607),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 437/885 (50%), Positives = 644/885 (73%), Gaps = 20/885 (2%)

Query  2    NKLVLIDGNSIANRAFYAL----PLLNNDKGVYTNAVYGFAMMLMNVLEKEKPSHVLVAF  57
            NKL+LIDG+S+A RAF+AL      ++N+ G+ TNA+YGF +ML +++ + +P+HVLVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  58   DAGKTTFRHTTFKGYKGGRQKTPSELSEQFPFIRELLTAYDIPQYELANYEADDIIGTLT  117
            DAGKTTFR   + +YK+GR KTP E+ EQF++IRE+LTA +I+ YEL +YEADDIIGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  118  KKAEADGM--EVAIITGDRDLTQLASEKTTVYITKKGIADMETNTPETLKEKYNLTPEQI  175
            K AE   +  +V+I++GD+DL QL+ E+T V I+KKG+A+ E  TP  L EK  LTP+Q+
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  176  IDMKGLMGDSSDNIPGIPGVGEKTALKLLHEFGGTVESVLEHAEEISGkklkekvlenke  235
            ID+K+LMGD SDNIPG+  +GEKT+LKLLHEFG ++E++ EH + +   K+KE+++++++
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFG-SLEGIYEHIDGFKTSKMKENLINDRD  243

Query  236  lAILSKELATINVDSPIECTVESTKYDGYQTEKVIPLLKEMNFTTLLKNIEGDTPEETKE  295
             A+LSK LATIN  SPI   ++   Y+G +   +  +  EM+F  L K + ++ P+E   
Sbjct  244  QAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEPVA  303

Query  296  LKELSFEIVTELKEKHFGGKTALYVELENDNYHTANFIGLTVHSSQGTYFFTKETAESSE  355
            +  +S++ VT++    F++   +Y E   DNYH   +IG++   ++  Y  T  +  +++
Sbjct  304  V--ISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLATD  361

Query  356  VFRKWVESDQTKVVYDAKKTMVAMNRIGLAISGITFDIMLASYLLNPSDSIDDFTSVAIR  415
             F++    ++    YD K++ V ++++G+ + + ++D  LA+YLL+  +  ++++++A  
Sbjct  362  SFKQ--VFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NELSTIA--  416

Query  416  HDYTEV--ETDEAVYGKGAKRSTPEESIVAAHLARKAVAIADLEKRLVDDLEENEQLALM  473
            + +T++  E D++VYGKGAKR+ P+  ++  HLARK   + D   +++D L  +EQL L 
Sbjct  417  RIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLY  476

Query  474  EDLELPLTFVLAEMEMQGVSVDTERLENMKVELAGRLKTLEESIHSLAGEEFNINSPKQL  533
            +++ELPL+ VLA ME++G+ V+   L++M  +    + +L + I  +AG+EFNINSPKQL
Sbjct  477  QNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQL  536

Query  534  GVILFEKLGLP--AVKKTKTGYSTAADVLESLSGKHAIIDEILLYRQLGKIQSTYIEGLL  591
            G ILFEK+ LP    KKTKTGYSTA DVLE L+   +I+  IL YRQ+ K+QSTY+ GL 
Sbjct  537  GSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQ  596

Query  592  KVTDKETHKVHTRFNQTLTQTGRLSSVDPNLQNIPIRLEEGRKIRQVFVPSKPGWKMFSA  651
                 +  K+HTR+ Q LTQTGRLSSVDPNLQNIPIRLE+GR IR+ F PS  +  ++S+
Sbjct  597  DYILADG-KIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSS  655

Query  652  DYSQVELRVLAHISEDENLIYAFKHDYDIHTKTAMDVFHVEQD-EVDSLMRRQAKAVNFG  710
            DYSQ+ELRVLAHIS DE+LI AF+++ DIHT TAM VF +++  +V +  RR+AKAVNFG
Sbjct  656  DYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFG  715

Query  711  IVYGISDYGLSQNLGITRKEAKDFIDRYFVSYPAVKEYMQDIVRFAKEKGYVETILHRRR  770
            IVYGISD+GLS+NLGITRK++K +ID YF  YP++K YM+++VR AK+KGYVET++ RRR
Sbjct  716  IVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRR  775

Query  771  YIPEIVSRNFNVRGFAERTAMNTPIQGSAADIIKKAMILMSERLVSEKLEAKLLLQVHDE  830
             +P+I SRNFNVR+FAERTA+N+PIQGSAADI+K AMI +   L +  + AK+LLQVHDE
Sbjct  776  ELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDE  835

Query  831  LIFEAPEAEIAKLEEIVPDVMENAVELSVPLKVDSAFGDTWYDAK  875
            +++E P+ E++ +  +V D ME AV+L+VPL VD + G++WY+AK
Sbjct  836  IVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

317) polA in NC_018593


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  689 bits (2604),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 439/885 (50%), Positives = 646/885 (73%), Gaps = 20/885 (2%)

Query  12   NKLVLIDGNSIANRAFYAL----PLLNNDKGVYTNAVYGFAMMLMNVLEKEKPSHVLVAF  67
            NKL+LIDG+S+A RAF+AL      ++N+ G+ TNA+YGF +ML +++ + +P+HVLVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  68   DAGKTTFRHTTFKGYKGGRQKTPSELSEQFPFIRELLTAYDIPQYELANYEADDIIGTLT  127
            DAGKTTFR   + +YK+GR KTP E+ EQF++IRE+LTA +I+ YEL +YEADDIIGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  128  KKAEADGM--EVAIITGDRDLTQLASEKTTVYITKKGIADMETNTPETLKEKYNLTPEQI  185
            K AE   +  +V+I++GD+DL QL+ E+T V I+KKG+A+ E  TP  L EK  LTP+Q+
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  186  IDMKGLMGDSSDNIPGIPGVGEKTALKLLHEFGGTVESVLEHAEEISGkklkekvlenke  245
            ID+K+LMGD SDNIPG+  +GEKT+LKLLHEFG ++E++ EH + +   K+KE+++++++
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFG-SLEGIYEHIDGFKTSKMKENLINDRD  243

Query  246  lAILSKELATINVDSPIECTVESTKYDGYQTEKVIPLLKEMNFTTLLKNIEGDTPeeske  305
             A+LSK LATIN  SPI   ++   Y+G +   +  +  EM+F  L K + ++ P+E+  
Sbjct  244  QAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEPVA  303

Query  306  lkelsFEIVTELKEQHFGGKTALYVELENDNYHTANFIGLTVHSSQGTYFFTKETAESSE  365
            +    ++ VT++  + F++   +Y E   DNYH   +IG++   ++  Y  T  +  +++
Sbjct  304  VIS--YQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLATD  361

Query  366  AFRKWVESDQTKVVYDAKKTIVAMNRIGLAISGITFDIMLASYLLNPSDSINDFTSVAVR  425
            +F++    ++    YD K++ V ++++G+ + + ++D  LA+YLL+  +  N+++++A  
Sbjct  362  SFKQ--VFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NELSTIA--  416

Query  426  HDYTEV--ETDEAVYGKGAKRSTPEESIVAAHLARKAVAIADLEKRLVDDLEKNEQLALM  483
            + +T++  E D++VYGKGAKR+ P+  ++  HLARK   + D   +++D L  +EQL L 
Sbjct  417  RIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLY  476

Query  484  EDLELPLTFVLAEMEMQGVSVDTDRLEDMKVELGGRLKTLEASIHSLAGEEFNINSPKQL  543
            +++ELPL+ VLA ME++G+ V+   L+DM  +    + +L   I  +AG+EFNINSPKQL
Sbjct  477  QNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQL  536

Query  544  GVILFEKLELP--PVKKTKTGYSTAADVLESLSGKHAIIDEILLYRQLGKIQSTYIEGLL  601
            G ILFEK++LP    KKTKTGYSTA DVLE L+   +I+  IL YRQ+ K+QSTY+ GL 
Sbjct  537  GSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQ  596

Query  602  KVTDKETHKVHTRFNQTLTQTGRLSSVDPNLQNIPIRLEEGRKIRQVFVPSKPGWKMFSA  661
                 +  K+HTR+ Q LTQTGRLSSVDPNLQNIPIRLE+GR IR+ F PS  +  ++S+
Sbjct  597  DYILADG-KIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSS  655

Query  662  DYSQVELRVLAHISEDENLIYAFKHDYDIHTKTAMDVFHVEKE-EVDSLMRRQAKAVNFG  720
            DYSQ+ELRVLAHIS DE+LI AF+++ DIHT TAM VF ++K  +V +  RR+AKAVNFG
Sbjct  656  DYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFG  715

Query  721  IVYGISDYGLSQNLGITRKEAKDFIDRYFVSYPAVKEYMQDIVRFAKEKGYVETILHRRR  780
            IVYGISD+GLS+NLGITRK++K +ID YF  YP++K YM+++VR AK+KGYVET++ RRR
Sbjct  716  IVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRR  775

Query  781  YIPEIVSRNFNVRGFAERTAMNTPIQGSAADIIKKAMILMSERLVSEKLKAKLLLQVHDE  840
             +P+I SRNFNVR+FAERTA+N+PIQGSAADI+K AMI +   L +  ++AK+LLQVHDE
Sbjct  776  ELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDE  835

Query  841  LIFEAPEAEIAKLEEIVPDVMENAVELSVPLKVDSAFGDTWYDAK  885
            +++E P+ E++ +  +V D ME AV+L+VPL VD + G++WY+AK
Sbjct  836  IVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

318) M639_09500 in NC_021837


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  689 bits (2604),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 439/885 (50%), Positives = 646/885 (73%), Gaps = 20/885 (2%)

Query  12   NKLVLIDGNSIANRAFYAL----PLLNNDKGVYTNAVYGFAMMLMNVLEKEKPSHVLVAF  67
            NKL+LIDG+S+A RAF+AL      ++N+ G+ TNA+YGF +ML +++ + +P+HVLVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  68   DAGKTTFRHTTFKGYKGGRQKTPSELSEQFPFIRELLTAYDIPQYELANYEADDIIGTLT  127
            DAGKTTFR   + +YK+GR KTP E+ EQF++IRE+LTA +I+ YEL +YEADDIIGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  128  KKAEADGM--EVAIITGDRDLTQLASEKTTVYITKKGIADMETNTPETLKEKYNLTPEQI  185
            K AE   +  +V+I++GD+DL QL+ E+T V I+KKG+A+ E  TP  L EK  LTP+Q+
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  186  IDMKGLMGDSSDNIPGIPGVGEKTALKLLHEFGGTVESVLEHAEEISGkklkekvlenke  245
            ID+K+LMGD SDNIPG+  +GEKT+LKLLHEFG ++E++ EH + +   K+KE+++++++
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFG-SLEGIYEHIDGFKTSKMKENLINDRD  243

Query  246  lAILSKELATINVDSPIECTVESTKYDGYQTEKVIPLLKEMNFTTLLKNIEGDTPeeske  305
             A+LSK LATIN  SPI   ++   Y+G +   +  +  EM+F  L K + ++ P+E+  
Sbjct  244  QAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEPVA  303

Query  306  lkelsFEIVTELKEQHFGGKTALYVELENDNYHTANFIGLTVHSSQGTYFFTKETAESSE  365
            +    ++ VT++  + F++   +Y E   DNYH   +IG++   ++  Y  T  +  +++
Sbjct  304  VIS--YQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLATD  361

Query  366  AFRKWVESDQTKVVYDAKKTIVAMNRIGLAISGITFDIMLASYLLNPSDSINDFTSVAVR  425
            +F++    ++    YD K++ V ++++G+ + + ++D  LA+YLL+  +  N+++++A  
Sbjct  362  SFKQ--VFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NELSTIA--  416

Query  426  HDYTEV--ETDEAVYGKGAKRSTPEESIVAAHLARKAVAIADLEKRLVDDLEKNEQLALM  483
            + +T++  E D++VYGKGAKR+ P+  ++  HLARK   + D   +++D L  +EQL L 
Sbjct  417  RIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLY  476

Query  484  EDLELPLTFVLAEMEMQGVSVDTDRLEDMKVELGGRLKTLEASIHSLAGEEFNINSPKQL  543
            +++ELPL+ VLA ME++G+ V+   L+DM  +    + +L   I  +AG+EFNINSPKQL
Sbjct  477  QNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQL  536

Query  544  GVILFEKLELP--PVKKTKTGYSTAADVLESLSGKHAIIDEILLYRQLGKIQSTYIEGLL  601
            G ILFEK++LP    KKTKTGYSTA DVLE L+   +I+  IL YRQ+ K+QSTY+ GL 
Sbjct  537  GSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQ  596

Query  602  KVTDKETHKVHTRFNQTLTQTGRLSSVDPNLQNIPIRLEEGRKIRQVFVPSKPGWKMFSA  661
                 +  K+HTR+ Q LTQTGRLSSVDPNLQNIPIRLE+GR IR+ F PS  +  ++S+
Sbjct  597  DYILADG-KIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSS  655

Query  662  DYSQVELRVLAHISEDENLIYAFKHDYDIHTKTAMDVFHVEKE-EVDSLMRRQAKAVNFG  720
            DYSQ+ELRVLAHIS DE+LI AF+++ DIHT TAM VF ++K  +V +  RR+AKAVNFG
Sbjct  656  DYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFG  715

Query  721  IVYGISDYGLSQNLGITRKEAKDFIDRYFVSYPAVKEYMQDIVRFAKEKGYVETILHRRR  780
            IVYGISD+GLS+NLGITRK++K +ID YF  YP++K YM+++VR AK+KGYVET++ RRR
Sbjct  716  IVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRR  775

Query  781  YIPEIVSRNFNVRGFAERTAMNTPIQGSAADIIKKAMILMSERLVSEKLKAKLLLQVHDE  840
             +P+I SRNFNVR+FAERTA+N+PIQGSAADI+K AMI +   L +  ++AK+LLQVHDE
Sbjct  776  ELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDE  835

Query  841  LIFEAPEAEIAKLEEIVPDVMENAVELSVPLKVDSAFGDTWYDAK  885
            +++E P+ E++ +  +V D ME AV+L+VPL VD + G++WY+AK
Sbjct  836  IVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

319) Bsel_1359 in NC_014219


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  689 bits (2606),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 429/885 (49%), Positives = 635/885 (72%), Gaps = 17/885 (1%)

Query  2    NKLVLIDGNSIAYRAFFAL----PLLNTDKGVYTNAVYGFTTMLLKVLEEQKPTHLMVAF  57
            NKL+LIDG+S+A+RAFFAL      ++ + G+ TNA+YGF  ML  ++   +PTH++VAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  58   DAGKSTFRHETFKEYKGKREKTPPELAEQLPVMRDLLKAFNIDHVELTNYEADDIIGTLA  117
            DAGK+TFR E + +YK+ R KTP E+ EQ++ +R++L A+ I   EL +YEADDIIGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  118  TQV-KGKEDWDVHIYTGDKDLLQLVNGQTTVHLTKKGITNVDTYQVKDIDERYGLKPEQI  176
                +     DV I +GDKDL+QL + +T V+++KKG+++ + +    + E+ GL P+Q+
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  177  IDMKGLMGDSSDNIPGVPGVGEKTALKLLKEHGSVEEVYQHLDEVSGkklkekleaneeq  236
            ID+K+LMGD SDNIPGV  +GEKT+LKLL E GS+E +Y+H+D     K+KE+L  + +Q
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRDQ  244

Query  237  alMSKQLATIFLEVPLEIKPDDLKRGEPDQAALSSLFKELEFQSLLSRIGeeeeeKVDME  296
            A++SK LATI    P+ I  DD+    PD A+LS ++ E++F  L   ++     ++  E
Sbjct  245  AFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLAS----QMPQE  300

Query  297  DLPVTRLSSDNPLENKHLVSPSALYVEMLEENYHQGSIIGVAIANETGIYYVEAEEALTS  356
             ++V        +    + +   +Y E L +NYH+ +IIG A ++   IY       L++
Sbjct  301  PVAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLAT  360

Query  357  DVFKKWAEDDQKEIYTFDAKRTVVALGWAGIDLSNTTFDIQMASYLIDPASGSHEIADIA  416
            D FK   +  QK I T+D KR+ V L+  GI+L   ++D ++A+YL+ ++   +E++ IA
Sbjct  361  DSFK---QVFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLL-STVEDNELSTIA  416

Query  417  NRKNGIQVQTDEAVYGKGKKQAIPEAEELSQHLGRKAAAILDLKKNLEQELRDNRQWELF  476
                +I ++ D++VYGKG K+A+P+ + L +HL+RK   +LD K ++ + L  + Q +L+
Sbjct  417  RIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLY  476

Query  477  QDLEMPLSVILGRMEANGVSVDQQELETIGKDLTERLAKLEQQIYEAAGQSFNINSPKQL  536
            Q++E+PL+ +L++ME +G+ V++  L+ ++ +    +  L Q+IY+ AGQ FNINSPKQL
Sbjct  477  QNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQL  536

Query  537  GKVLFEDLGLP--VLKKTKTGYSTSADVLEKLKGEHDVIDHILFYRQLGKLNSTYIEGLL  594
            G +LFE + LP  + KKTKTGYST+ DVLE+L     ++  IL YRQ+ KL+STY+ GL 
Sbjct  537  GSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQ  596

Query  595  KVIHPKTGKIHTIFNQAVTQTGRLSSTEPNLQNIPVRLEEGRKIRRAFVPSKPGSKLFAA  654
              I +  GKIHT + Q +TQTGRLSS +PNLQNIP+RLE+GR IR+AF PS  ++ L+++
Sbjct  597  DYILAD-GKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSS  655

Query  655  DYSQIELRVLAHISKDENLISAFQEGMDIHTKTASDVFGV-KGNEVTAEMRRTAKAVNFG  713
            DYSQIELRVLAHIS DE+LI+AF+EG DIHT TA  VFG+ K+ +VTA+ RR AKAVNFG
Sbjct  656  DYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFG  715

Query  714  IVYGISDYGLSQNLGISRKKAQTFIDKYFESYPGVKTYMEDIVAEAREQGYVTTMLQRRR  773
            IVYGISD+GLS+NLGI+RK+++++ID YFE YPG+K+YME++V EA+++GYV T+++RRR
Sbjct  716  IVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRR  775

Query  774  YLPDLTSRNFNQRSFAERTAMNTPIQGSAADIIKKAMVDMATELERQNLKSVMLLQVHDE  833
             LPD+ SRNFN RSFAERTA+N+PIQGSAADI+K AM+++   L+   +++ MLLQVHDE
Sbjct  776  ELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDE  835

Query  834  LIFEVPEDEIETMEKLVKDVMESTIELNVPLITDMATGDTWYDAK  878
            +++EVP+DE+ ++ KLVKD ME++++L VPL  D +TG++WY+AK
Sbjct  836  IVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

320) polA in NC_002976


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  689 bits (2605),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 424/892 (48%), Positives = 637/892 (72%), Gaps = 33/892 (3%)

Query  2    NKLVLIDGNSLSFRAFYAL----PLLSNHAGIHTNAVYGFAMLLEKIIKEEKPNHFLVAF  57
            NKL+LIDG+S++FRAF+AL      + NH+G+HTNA+YGF ++L+ ++K  +P H LVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  58   DAGKTTFRHSKYSEYKGGRQKTPPELSEQFPYIRQLLDAYHIKRYELDNYEADDIIGTLS  117
            DAGKTTFR   Y++YK+GR KTP E+ EQF+YIR++L A  I  YEL++YEADDIIGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  118  RQADEED--FETIIITGDRDLTQLATDNVTIYYTKKGVTDVDHYTPKFIAEKYNGLVPKQ  175
            + A+  +  F+  I++GD+DL QL+ +N  +  +KKGV++ +++TP ++ EK  GL P+Q
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEK-MGLTPNQ  183

Query  176  IIDMKGLMGDTSDNIPGVAGVGEKTAIKLLNQFESVEGVYEHIEEVTAKKLKEKLINSKD  235
            +ID+K+LMGD SDNIPGV+ +GEKT++KLL++F S+EG+YEHI+   + K+KE+LIN +D
Sbjct  184  FIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRD  243

Query  236  DALMSKDLATINVHSPIEVSLEDTKLTLQDDTTekielfkklefkqllADIDTSSTNEEV  295
            +A++SK LATIN  SPI ++L+D       D +   +++  ++F QL  ++ +   +E V
Sbjct  244  QAFLSKTLATINTASPITIGLDDIVYN-GPDVASLSQFYDEMDFVQLKKGLASQMPQEPV  302

Query  296  IDKTFEIEQDFQNVDLNDL--NEAVIHFELEGTNYLKDTILKFG------FYTNHQHVVI  347
               ++   Q+  NV   DL   E ++ FE    NY +++I+ F+      +Y++ +  ++
Sbjct  303  AVISY---QEVTNVS-ADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLL  358

Query  348  NAEDVKDYKHLVQWLEDKNTTKIVYDAKKTYVSAHRLGINIENIEFDVMLASYIIDPSRS  407
             ++    +K++ Q           YD K++ V   +LGI++    +D  LA+Y++     
Sbjct  359  ATDS---FKQVFQ------KPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED  409

Query  408  IDDVKSVVSLYGQNYVKDNITIFGKGKKHHIPEEPILNEHIASVTEAIAAVTPTMKSQLE  467
             +++ ++  ++ +  + ++ T++GKG K+ +P+  +L EH+A     +    + M  +L 
Sbjct  410  -NELSTIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLT  468

Query  468  DYNQIELLKDLELPLARILSEMEEIGIYTDINDLKEMEFEIQKKLDVLISNIHESAGEAF  527
              +Q++L +++ELPLA +L+ ME  GI  +   L++M  + +  ++ L  +I + AG+ F
Sbjct  469  AHEQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEF  528

Query  528  NINSPKQLGVVLFETLQLP--VIKKTKTGYSTAVDVLEKLQGEHPIIDDILEYRQLAKLQ  585
            NINSPKQLG +LFE +QLP  + KKTKTGYSTAVDVLE+L    PI+  IL+YRQ++KLQ
Sbjct  529  NINSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQ  588

Query  586  STYVEGLQKVISKDHRIHTRFNQTLAQTGRLSSIDPNLQNIPIRLEEGRKIRKAFKPTSK  645
            STYV GLQ  I  D +IHTR+ Q L+QTGRLSS+DPNLQNIPIRLE+GR IRKAF P+  
Sbjct  589  STYVIGLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHE  648

Query  646  DSVILSADYSQIELRVLAHITQDESLKHAFINGHDIHTATAMKVFNVE-SDQVDSLMRRQ  704
            D+V+LS+DYSQIELRVLAHI+ DE L  AF +G DIHT+TAM+VF ++ + +V +  RR+
Sbjct  649  DAVLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRN  708

Query  705  AKAVNFGIVYGISDYGLSQSLGITRKQAKAFIDDYLASFPGVKQYMSDIVKDAKAQGYVE  764
            AKAVNFGIVYGISD+GLS++LGITRKQ+K++ID Y+  +PG+K YM ++V++AK +GYVE
Sbjct  709  AKAVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVE  768

Query  765  TLLHRRRYIPDITSRNVNLRSFAERTAMNTPIQGSAADIIKLAMVKFSEKIKETKYHAKL  824
            TL+ RRR +PDI SRN N+RSFAERTA+N+PIQGSAADI+K+AM+++   ++   ++AK+
Sbjct  769  TLFKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKM  828

Query  825  LLQVHDELIFEIPKSEVEDFSKFVEEIMEQALVLDVPLKVDSNYGATWYDAK  876
            LLQVHDE+++E+P+ E+  + K+V + ME A+ L VPL VD + G +WY+AK
Sbjct  829  LLQVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

321) WKK_00380 in NC_015759


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  687 bits (2597),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 455/899 (51%), Positives = 648/899 (73%), Gaps = 27/899 (3%)

Query  2    GKPKLLLIDGNSLAFRAFYALINQVDRFVNHDGLHTNALVGFNNLLDGIVDPFEPDKALV  61
             K KLLLIDG+S+AFRAF+AL NQ+DRF NH GLHTNA+ GF+ +LD ++    P   LV
Sbjct  3    NKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLV  62

Query  62   AWDAGKTTFRTNAYDNYKGNRDKTPQELVEQFEPLREMVRLHGITNYELADYEADDIIGT  121
            A DAGKTTFRT+ Y +YK+ R KTP+E+ EQF  +REM+   GI+ YEL +YEADDIIGT
Sbjct  63   AFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGT  122

Query  122  MAHAG--VESGYAVTIVTGDRDMRQLVDDDITVWITKKGISEIDKYTPAEVADVYGGLTP  179
            +   +   E  + VTIV+GD+D+ QL D++  V I+KKG++E++ +TPA + +   GLTP
Sbjct  123  LDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEK-MGLTP  181

Query  180  KQVIEVKGLQGDPSDNYPGVPGIGEKTAIKLIQEYHDIPELYEQIDMMKKSKRKENLIQY  239
            +Q I++K+L GD SDN PGV  IGEKT++KL++E+  +  +YE+ID  K SK KENLI+ 
Sbjct  182  NQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIND  241

Query  240  KDDAFLSRDLARIRLDAPVTLDLDDLAYRGIQYQDLIPFYQHLDFKQQLVKLANQGYTIT  299
            +D+AFLS+ LA I   +P+T++LDD+ Y G +   L  FY+++DF Q    LA+Q     
Sbjct  242  RDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQ-----  296

Query  300  GTQNESNPTVKLNVAPLTANNLAHVEALQDDVDFYVELDGENYHRAAIVGFVIGNQQQGY  359
               +E+ + +  +     + +L   E +     FY E   +NYHR AI+GF  G+ +Q Y
Sbjct  297  -MPQEPVAVISYQEVTNVSADLFSAEDI-----FYFETLRDNYHREAIIGFAWGHGEQIY  350

Query  360  LASRDLELLSQDTPVKRILENNKIKKNVFNSKETFVALHRYNVDLTGVDFDLLLVSYLLN  419
             AS DL LL+ D+  K+++++       ++ K + V L +  ++L +  +D  L +YLL+
Sbjct  351  -ASTDLSLLATDS-FKQVFQKPI---ATYDFKRSKVLLSHLGIELVAPSYDARLANYLLS  405

Query  420  VNDNSNDLGTIAHEHNYFDVQTDDEVYGKGAKFAIIDNDTDFFEHLGRKAQAIGALKQPL  479
              ++ N+L+TIA+    + ++ DD VYGKGAK A+ D+D  ++EHL+RK + +   K  +
Sbjct  406  TVED-NELSTIARIFTDISLEEDDTVYGKGAKRAVPDKDV-LLEHLARKVKVLLDSKSQM  463

Query  480  MQKLDEHEQTDLYTEIELPLTFVLAHMEINGITVNAERLLGMQSKLTERLSELEQTIHQQ  539
            ++KL  HEQ DLY +IELPL+ VLA MEI+GI VN   L +M  +    +  L Q I + 
Sbjct  464  LDKLTAHEQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDM  523

Query  540  AGHEFNIQSPKQLGVILFEEMGLKPL---KKTKTGYSTSVEVLEQMTDV-PLVASILQYR  595
            AG+EFNI+SPKQLG ILFE M L PL   KKTKTGYST+V+VLE+++ + P+VA IL+YR
Sbjct  524  AGQEFNINSPKQLGSILFEKMQL-PLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYR  582

Query  596  QLAKILSTYVDGLLRVIHGSDSKVHTRYLQTLTQTGRLSSIDPNLQNIPVRVEEGRQIRK  655
            Q++K+ STYV GL   I + D+K+HTRY+Q LTQTGRLSS+DPNLQNIP+R+E+GR IRK
Sbjct  583  QITKLQSTYVIGLQDYILA-DGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRK  641

Query  656  AFEPQQAGWSLLSADYSQIELRVLAHITNDEKMRQAFINDEDIHAATARRIFGLAEDAVV  715
            AF P + +  LLS+DYSQIELRVLAHI+ DE +  AF ++ DIH++TA R+FG+   A V
Sbjct  642  AFTPSHEDAVLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADV  701

Query  716  DSNLRRQAKAVNFGIVYGISEFGLAKNIGTDRKTAKSIIDTYLNEYSGVKKWTEEIILDA  775
             +N RR+AKAVNFGIVYGIS+FGL++N+G  RK +KS IDTY++ Y+G+K   E+++ +A
Sbjct  702  TANDRRNAKAVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREA  761

Query  776  REKGYVETIAHRRRYLPDIKAKSFNARSFAERTAMNTPVQGSaadiikiamikmQSVMEQ  835
            ++KGYVET+  RRR LPDI++++FN RSFAERTA+N+P+QGSAADI+KIAMI+++  ++ 
Sbjct  762  KDKGYVETLFKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQA  821

Query  836  KQLKSKMLLQVHDELIFEVPEDELTLMHKLVPEVMDSAVKLTVPLKVETHEGKTWYDAK  894
              +++KMLLQVHDE+++EVP+DELT + KLV + M++AV L+VPL V+   G++WY+AK
Sbjct  822  GGFRAKMLLQVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

322) polA in NC_018588


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  687 bits (2596),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 438/885 (50%), Positives = 645/885 (73%), Gaps = 20/885 (2%)

Query  12   NKLVLIDGNSIANRAFYAL----PLLNNDKGVYTNAVYGFAMMLMNVLEKEKPSHVLVAF  67
            NKL+LIDG+S+A RAF+AL      ++N+ G+ TNA+YGF +ML +++ + +P+HVLVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  68   DAGKTTFRHTTFKGYKGGRQKTPSELSEQFPFIRELLTAYDIPQYELANYEADDIIGTLT  127
            DAGKTTFR   + +YK+GR KTP E+ EQF++IRE+LTA +I+ YEL +YEADDIIGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  128  KKAEADGM--EVAIITGDRDLTQLASEKTTVYITKKGIADMETNTPETLKEKYNLTPEQI  185
            K AE   +  +V+I++GD+DL QL+ E+T V I+KKG+A+ E  TP  L EK  LTP+Q+
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  186  IDMKGLMGDSSDNIPGIPGVGEKTALKLLHEFGGTVESVLEHAEEISGkklkekvlenke  245
            ID+K+LMGD SDNIPG+  +GEKT+LKLLHEFG ++E++ EH + +   K+KE+++++++
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFG-SLEGIYEHIDGFKTSKMKENLINDRD  243

Query  246  lAILSKELATINVDSPIECTVESTKYDGYQTEKVIPLLKEMNFTTLLKNIEGDTPeeske  305
             A+LSK LATIN  SPI   ++   Y+G +   +  +  EM+F  L K + ++ P+E+  
Sbjct  244  QAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEPVA  303

Query  306  lkelsFEIVTELKEQHFGGKTALYVELENDNYHTANFIGLTVHSSQGTYFFTKETAESSE  365
            +    ++ VT++  + F++   +Y E   DNYH   +IG++   ++  Y  T  +  +++
Sbjct  304  VIS--YQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLATD  361

Query  366  AFRKWVESDQTKVVYDAKKTIVAMNRIGLAISGITFDIMLASYLLNPSDSIDDFTSVAVR  425
            +F++    ++    YD K++ V ++++G+ + + ++D  LA+YLL+  +  ++++++A  
Sbjct  362  SFKQ--VFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NELSTIA--  416

Query  426  HDYTEV--ETDEAVYGKGAKRSTPEESIVAAHLARKAVAIADLEKRLVDDLEKNEQLALM  483
            + +T++  E D++VYGKGAKR+ P+  ++  HLARK   + D   +++D L  +EQL L 
Sbjct  417  RIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLY  476

Query  484  EDLELPLTFVLAEMEMQGVSVDTDRLEDMKVELGGRLKTLEASIHSLAGEEFNINSPKQL  543
            +++ELPL+ VLA ME++G+ V+   L+DM  +    + +L   I  +AG+EFNINSPKQL
Sbjct  477  QNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQL  536

Query  544  GVILFEKLELP--PVKKTKTGYSTAADVLESLSGKHAIIDEILLYRQLGKIQSTYIEGLL  601
            G ILFEK++LP    KKTKTGYSTA DVLE L+   +I+  IL YRQ+ K+QSTY+ GL 
Sbjct  537  GSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQ  596

Query  602  KVTDKETHKVHTRFNQTLTQTGRLSSVDPNLQNIPIRLEEGRKIRQVFVPSKPGWKMFSA  661
                 +  K+HTR+ Q LTQTGRLSSVDPNLQNIPIRLE+GR IR+ F PS  +  ++S+
Sbjct  597  DYILADG-KIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSS  655

Query  662  DYSQVELRVLAHISEDENLIYAFKHDYDIHTKTAMDVFHVEKE-EVDSLMRRQAKAVNFG  720
            DYSQ+ELRVLAHIS DE+LI AF+++ DIHT TAM VF ++K  +V +  RR+AKAVNFG
Sbjct  656  DYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFG  715

Query  721  IVYGISDYGLSQNLGITRKEAKDFIDRYFVSYPAVKEYMQDIVRFAKEKGYVETILHRRR  780
            IVYGISD+GLS+NLGITRK++K +ID YF  YP++K YM+++VR AK+KGYVET++ RRR
Sbjct  716  IVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRR  775

Query  781  YIPEIVSRNFNVRGFAERTAMNTPIQGSAADIIKKAMILMSERLVSEKLEAKLLLQVHDE  840
             +P+I SRNFNVR+FAERTA+N+PIQGSAADI+K AMI +   L +  + AK+LLQVHDE
Sbjct  776  ELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDE  835

Query  841  LIFEAPEAEIAKLEEIVPDVMENAVELSVPLKVDSAFGDTWYDAK  885
            +++E P+ E++ +  +V D ME AV+L+VPL VD + G++WY+AK
Sbjct  836  IVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

323) polA in NC_018589


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  687 bits (2596),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 438/885 (50%), Positives = 645/885 (73%), Gaps = 20/885 (2%)

Query  12   NKLVLIDGNSIANRAFYAL----PLLNNDKGVYTNAVYGFAMMLMNVLEKEKPSHVLVAF  67
            NKL+LIDG+S+A RAF+AL      ++N+ G+ TNA+YGF +ML +++ + +P+HVLVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  68   DAGKTTFRHTTFKGYKGGRQKTPSELSEQFPFIRELLTAYDIPQYELANYEADDIIGTLT  127
            DAGKTTFR   + +YK+GR KTP E+ EQF++IRE+LTA +I+ YEL +YEADDIIGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  128  KKAEADGM--EVAIITGDRDLTQLASEKTTVYITKKGIADMETNTPETLKEKYNLTPEQI  185
            K AE   +  +V+I++GD+DL QL+ E+T V I+KKG+A+ E  TP  L EK  LTP+Q+
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  186  IDMKGLMGDSSDNIPGIPGVGEKTALKLLHEFGGTVESVLEHAEEISGkklkekvlenke  245
            ID+K+LMGD SDNIPG+  +GEKT+LKLLHEFG ++E++ EH + +   K+KE+++++++
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFG-SLEGIYEHIDGFKTSKMKENLINDRD  243

Query  246  lAILSKELATINVDSPIECTVESTKYDGYQTEKVIPLLKEMNFTTLLKNIEGDTPeeske  305
             A+LSK LATIN  SPI   ++   Y+G +   +  +  EM+F  L K + ++ P+E+  
Sbjct  244  QAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEPVA  303

Query  306  lkelsFEIVTELKEQHFGGKTALYVELENDNYHTANFIGLTVHSSQGTYFFTKETAESSE  365
            +    ++ VT++  + F++   +Y E   DNYH   +IG++   ++  Y  T  +  +++
Sbjct  304  VIS--YQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLATD  361

Query  366  AFRKWVESDQTKVVYDAKKTIVAMNRIGLAISGITFDIMLASYLLNPSDSIDDFTSVAVR  425
            +F++    ++    YD K++ V ++++G+ + + ++D  LA+YLL+  +  ++++++A  
Sbjct  362  SFKQ--VFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NELSTIA--  416

Query  426  HDYTEV--ETDEAVYGKGAKRSTPEESIVAAHLARKAVAIADLEKRLVDDLEKNEQLALM  483
            + +T++  E D++VYGKGAKR+ P+  ++  HLARK   + D   +++D L  +EQL L 
Sbjct  417  RIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLY  476

Query  484  EDLELPLTFVLAEMEMQGVSVDTDRLEDMKVELGGRLKTLEASIHSLAGEEFNINSPKQL  543
            +++ELPL+ VLA ME++G+ V+   L+DM  +    + +L   I  +AG+EFNINSPKQL
Sbjct  477  QNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQL  536

Query  544  GVILFEKLELP--PVKKTKTGYSTAADVLESLSGKHAIIDEILLYRQLGKIQSTYIEGLL  601
            G ILFEK++LP    KKTKTGYSTA DVLE L+   +I+  IL YRQ+ K+QSTY+ GL 
Sbjct  537  GSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQ  596

Query  602  KVTDKETHKVHTRFNQTLTQTGRLSSVDPNLQNIPIRLEEGRKIRQVFVPSKPGWKMFSA  661
                 +  K+HTR+ Q LTQTGRLSSVDPNLQNIPIRLE+GR IR+ F PS  +  ++S+
Sbjct  597  DYILADG-KIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSS  655

Query  662  DYSQVELRVLAHISEDENLIYAFKHDYDIHTKTAMDVFHVEKE-EVDSLMRRQAKAVNFG  720
            DYSQ+ELRVLAHIS DE+LI AF+++ DIHT TAM VF ++K  +V +  RR+AKAVNFG
Sbjct  656  DYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFG  715

Query  721  IVYGISDYGLSQNLGITRKEAKDFIDRYFVSYPAVKEYMQDIVRFAKEKGYVETILHRRR  780
            IVYGISD+GLS+NLGITRK++K +ID YF  YP++K YM+++VR AK+KGYVET++ RRR
Sbjct  716  IVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRR  775

Query  781  YIPEIVSRNFNVRGFAERTAMNTPIQGSAADIIKKAMILMSERLVSEKLEAKLLLQVHDE  840
             +P+I SRNFNVR+FAERTA+N+PIQGSAADI+K AMI +   L +  + AK+LLQVHDE
Sbjct  776  ELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDE  835

Query  841  LIFEAPEAEIAKLEEIVPDVMENAVELSVPLKVDSAFGDTWYDAK  885
            +++E P+ E++ +  +V D ME AV+L+VPL VD + G++WY+AK
Sbjct  836  IVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

324) polA in NC_018586


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  687 bits (2599),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 436/885 (50%), Positives = 643/885 (73%), Gaps = 20/885 (2%)

Query  12   NKLVLIDGNSIANRAFYAL----PLLNNDKGVYTNAVYGFAMMLMNVLEKEKPSHVLVAF  67
            NKL+LIDG+S+A RAF+AL      ++N+ G+ TNA+YGF +ML +++ + +P+HVLVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  68   DAGKTTFRHTTFKGYKGGRQKTPSELSEQFPFIRELLTAYDIPQYELANYEADDIIGTLT  127
            DAGKTTFR   + +YK+GR KTP E+ EQF++IRE+LTA +I+ YEL +YEADDIIGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  128  KKAEADGM--EVAIITGDRDLTQLASEKTTVYITKKGIADMETNTPETLKEKYNLTPQQI  185
            K AE   +  +V+I++GD+DL QL+ E+T V I+KKG+A+ E  TP  L EK  LTP+Q+
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  186  IDMKGLMGDSSDNIPGIPGVGEKTALKLLHEFGGTVESVLEHAEEISGkklkekvlenke  245
            ID+K+LMGD SDNIPG+  +GEKT+LKLLHEFG ++E++ EH + +   K+KE+++++++
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFG-SLEGIYEHIDGFKTSKMKENLINDRD  243

Query  246  lAILSKELATINVDSPIECTVESTKYDGYQTEKVIPLLKEMNFTTLLKNIEGDTPEETKE  305
             A+LSK LATIN  SPI   ++   Y+G +   +  +  EM+F  L K + ++ P+E   
Sbjct  244  QAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEPVA  303

Query  306  LKELSFEIVTELKEKHFGGKTALYVELENDNYHTANFIGLTVHSSQGTYFFTKETAESSE  365
            +  +S++ VT++    F++   +Y E   DNYH   +IG++   ++  Y  T  +  +++
Sbjct  304  V--ISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLATD  361

Query  366  VFRKWVESDQTKVVYDAKKTMVAMNRIGLAISGITFDIMLASYLLNPSDSIDDFTSVAIR  425
             F++    ++    YD K++ V ++++G+ + + ++D  LA+YLL+  +  ++++++A  
Sbjct  362  SFKQ--VFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NELSTIA--  416

Query  426  HDYTEV--ETDEAVYGKGAKRSTPEESIVAAHLARKAVAIADLEKRLVDDLEENEQLALM  483
            + +T++  E D++VYGKGAKR+ P+  ++  HLARK   + D   +++D L  +EQL L 
Sbjct  417  RIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLY  476

Query  484  EDLELPLTFVLAEMEMQGVSVDTERLENTKVELAGRLKTLEESIHSLAGEEFNINSPKQL  543
            +++ELPL+ VLA ME++G+ V+   L++   +    + +L + I  +AG+EFNINSPKQL
Sbjct  477  QNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQL  536

Query  544  GVILFEKLGLP--AVKKTKTGYSTAADVLESLSGKHAIIDEILLYRQLGKIQSTYIEGLL  601
            G ILFEK+ LP    KKTKTGYSTA DVLE L+   +I+  IL YRQ+ K+QSTY+ GL 
Sbjct  537  GSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQ  596

Query  602  KVTDKETHKVHTRFNQTLTQTGRLSSVDPNLQNIPIRLEEGRKIRQVFVPSKPGWKMFSA  661
                 +  K+HTR+ Q LTQTGRLSSVDPNLQNIPIRLE+GR IR+ F PS  +  ++S+
Sbjct  597  DYILADG-KIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSS  655

Query  662  DYSQVELRVLAHISEDENLIYAFKHDYDIHTKTAMDVFHVEQD-EVDSLMRRQAKAVNFG  720
            DYSQ+ELRVLAHIS DE+LI AF+++ DIHT TAM VF +++  +V +  RR+AKAVNFG
Sbjct  656  DYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFG  715

Query  721  IVYGISDYGLSQNLGITRKEAKDFIDRYFVSYPAVKEYMQDIVRFAKEKGYVETILHRRR  780
            IVYGISD+GLS+NLGITRK++K +ID YF  YP++K YM+++VR AK+KGYVET++ RRR
Sbjct  716  IVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRR  775

Query  781  YIPEIVSRNFNVRGFAERTAMNTPIQGSAADIIKKAMILMSERLVSEKLEAKLLLQVHDE  840
             +P+I SRNFNVR+FAERTA+N+PIQGSAADI+K AMI +   L +  + AK+LLQVHDE
Sbjct  776  ELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDE  835

Query  841  LIFEAPEAEIAKLEEIVPDVMENAVELSVPLKVDSAFGDTWYDAK  885
            +++E P+ E++ +  +V D ME AV+L+VPL VD + G++WY+AK
Sbjct  836  IVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

325) M642_05760 in NC_021823


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  687 bits (2596),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 438/885 (50%), Positives = 645/885 (73%), Gaps = 20/885 (2%)

Query  12   NKLVLIDGNSIANRAFYAL----PLLNNDKGVYTNAVYGFAMMLMNVLEKEKPSHVLVAF  67
            NKL+LIDG+S+A RAF+AL      ++N+ G+ TNA+YGF +ML +++ + +P+HVLVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  68   DAGKTTFRHTTFKGYKGGRQKTPSELSEQFPFIRELLTAYDIPQYELANYEADDIIGTLT  127
            DAGKTTFR   + +YK+GR KTP E+ EQF++IRE+LTA +I+ YEL +YEADDIIGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  128  KKAEADGM--EVAIITGDRDLTQLASEKTTVYITKKGIADMETNTPETLKEKYNLTPEQI  185
            K AE   +  +V+I++GD+DL QL+ E+T V I+KKG+A+ E  TP  L EK  LTP+Q+
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  186  IDMKGLMGDSSDNIPGIPGVGEKTALKLLHEFGGTVESVLEHAEEISGkklkekvlenke  245
            ID+K+LMGD SDNIPG+  +GEKT+LKLLHEFG ++E++ EH + +   K+KE+++++++
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFG-SLEGIYEHIDGFKTSKMKENLINDRD  243

Query  246  lAILSKELATINVDSPIECTVESTKYDGYQTEKVIPLLKEMNFTTLLKNIEGDTPeeske  305
             A+LSK LATIN  SPI   ++   Y+G +   +  +  EM+F  L K + ++ P+E+  
Sbjct  244  QAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEPVA  303

Query  306  lkelsFEIVTELKEQHFGGKTALYVELENDNYHTANFIGLTVHSSQGTYFFTKETAESSE  365
            +    ++ VT++  + F++   +Y E   DNYH   +IG++   ++  Y  T  +  +++
Sbjct  304  VIS--YQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLATD  361

Query  366  AFRKWVESDQTKVVYDAKKTIVAMNRIGLAISGITFDIMLASYLLNPSDSIDDFTSVAVR  425
            +F++    ++    YD K++ V ++++G+ + + ++D  LA+YLL+  +  ++++++A  
Sbjct  362  SFKQ--VFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NELSTIA--  416

Query  426  HDYTEV--ETDEAVYGKGAKRSTPEESIVAAHLARKAVAIADLEKRLVDDLEKNEQLALM  483
            + +T++  E D++VYGKGAKR+ P+  ++  HLARK   + D   +++D L  +EQL L 
Sbjct  417  RIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLY  476

Query  484  EDLELPLTFVLAEMEMQGVSVDTDRLEDMKVELGGRLKTLEASIHSLAGEEFNINSPKQL  543
            +++ELPL+ VLA ME++G+ V+   L+DM  +    + +L   I  +AG+EFNINSPKQL
Sbjct  477  QNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQL  536

Query  544  GVILFEKLELP--PVKKTKTGYSTAADVLESLSGKHAIIDEILLYRQLGKIQSTYIEGLL  601
            G ILFEK++LP    KKTKTGYSTA DVLE L+   +I+  IL YRQ+ K+QSTY+ GL 
Sbjct  537  GSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQ  596

Query  602  KVTDKETHKVHTRFNQTLTQTGRLSSVDPNLQNIPIRLEEGRKIRQVFVPSKPGWKMFSA  661
                 +  K+HTR+ Q LTQTGRLSSVDPNLQNIPIRLE+GR IR+ F PS  +  ++S+
Sbjct  597  DYILADG-KIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSS  655

Query  662  DYSQVELRVLAHISEDENLIYAFKHDYDIHTKTAMDVFHVEKE-EVDSLMRRQAKAVNFG  720
            DYSQ+ELRVLAHIS DE+LI AF+++ DIHT TAM VF ++K  +V +  RR+AKAVNFG
Sbjct  656  DYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFG  715

Query  721  IVYGISDYGLSQNLGITRKEAKDFIDRYFVSYPAVKEYMQDIVRFAKEKGYVETILHRRR  780
            IVYGISD+GLS+NLGITRK++K +ID YF  YP++K YM+++VR AK+KGYVET++ RRR
Sbjct  716  IVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRR  775

Query  781  YIPEIVSRNFNVRGFAERTAMNTPIQGSAADIIKKAMILMSERLVSEKLEAKLLLQVHDE  840
             +P+I SRNFNVR+FAERTA+N+PIQGSAADI+K AMI +   L +  + AK+LLQVHDE
Sbjct  776  ELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDE  835

Query  841  LIFEAPEAEIAKLEEIVPDVMENAVELSVPLKVDSAFGDTWYDAK  885
            +++E P+ E++ +  +V D ME AV+L+VPL VD + G++WY+AK
Sbjct  836  IVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

326) polA in NC_013768


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  686 bits (2595),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 438/885 (50%), Positives = 645/885 (73%), Gaps = 20/885 (2%)

Query  2    NKLVLIDGNSIANRAFYAL----PLLNNDKGVYTNAVYGFAMMLMNVLEKEKPSHVLVAF  57
            NKL+LIDG+S+A RAF+AL      ++N+ G+ TNA+YGF +ML +++ + +P+HVLVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  58   DAGKTTFRHTTFKGYKGGRQKTPSELSEQFPFIRELLTAYDIPQYELANYEADDIIGTLT  117
            DAGKTTFR   + +YK+GR KTP E+ EQF++IRE+LTA +I+ YEL +YEADDIIGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  118  KKAEADGM--EVAIITGDRDLTQLASEKTTVYITKKGIADMETNTPETLKEKYNLTPEQI  175
            K AE   +  +V+I++GD+DL QL+ E+T V I+KKG+A+ E  TP  L EK  LTP+Q+
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  176  IDMKGLMGDSSDNIPGIPGVGEKTALKLLHEFGGTVESVLEHAEEISGkklkekvlenke  235
            ID+K+LMGD SDNIPG+  +GEKT+LKLLHEFG ++E++ EH + +   K+KE+++++++
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFG-SLEGIYEHIDGFKTSKMKENLINDRD  243

Query  236  lAILSKELATINVDSPIECTVESTKYDGYQTEKVIPLLKEMNFTTLLKNIEGDTPeeske  295
             A+LSK LATIN  SPI   ++   Y+G +   +  +  EM+F  L K + ++ P+E+  
Sbjct  244  QAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEPVA  303

Query  296  lkelsFEIVTELKEQHFGGKTALYVELENDNYHTANFIGLTVHSSQGTYFFTKETAESSE  355
            +    ++ VT++  + F++   +Y E   DNYH   +IG++   ++  Y  T  +  +++
Sbjct  304  VIS--YQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLATD  361

Query  356  AFRKWVESDQTKVVYDAKKTIVAMNRIGLAISGITFDIMLASYLLNPSDSIDDFTSVAVR  415
            +F++    ++    YD K++ V ++++G+ + + ++D  LA+YLL+  +  ++++++A  
Sbjct  362  SFKQ--VFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NELSTIA--  416

Query  416  HDYTEV--ETDEAVYGKGAKRSTPEESIVAAHLARKAVAIADLEKRLVDDLEKNEQLALM  473
            + +T++  E D++VYGKGAKR+ P+  ++  HLARK   + D   +++D L  +EQL L 
Sbjct  417  RIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLY  476

Query  474  EDLELPLTFVLAEMEMQGVSVDTDRLEDMKVELGGRLKTLEASIHSLAGEEFNINSPKQL  533
            +++ELPL+ VLA ME++G+ V+   L+DM  +    + +L   I  +AG+EFNINSPKQL
Sbjct  477  QNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQL  536

Query  534  GVILFEKLELP--PVKKTKTGYSTAADVLESLSGKHAIIDEILLYRQLGKIQSTYIEGLL  591
            G ILFEK++LP    KKTKTGYSTA DVLE L+   +I+  IL YRQ+ K+QSTY+ GL 
Sbjct  537  GSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQ  596

Query  592  KVTDKETHKVHTRFNQTLTQTGRLSSVDPNLQNIPIRLEEGRKIRQVFVPSKPGWKMFSA  651
                 +  K+HTR+ Q LTQTGRLSSVDPNLQNIPIRLE+GR IR+ F PS  +  ++S+
Sbjct  597  DYILADG-KIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSS  655

Query  652  DYSQVELRVLAHISEDENLIYAFKHDYDIHTKTAMDVFHVEKE-EVDSLMRRQAKAVNFG  710
            DYSQ+ELRVLAHIS DE+LI AF+++ DIHT TAM VF ++K  +V +  RR+AKAVNFG
Sbjct  656  DYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFG  715

Query  711  IVYGISDYGLSQNLGITRKEAKDFIDRYFVSYPAVKEYMQDIVRFAKEKGYVETILHRRR  770
            IVYGISD+GLS+NLGITRK++K +ID YF  YP++K YM+++VR AK+KGYVET++ RRR
Sbjct  716  IVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRR  775

Query  771  YIPEIVSRNFNVRGFAERTAMNTPIQGSAADIIKKAMILMSERLVSEKLEAKLLLQVHDE  830
             +P+I SRNFNVR+FAERTA+N+PIQGSAADI+K AMI +   L +  + AK+LLQVHDE
Sbjct  776  ELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDE  835

Query  831  LIFEAPEAEIAKLEEIVPDVMENAVELSVPLKVDSAFGDTWYDAK  875
            +++E P+ E++ +  +V D ME AV+L+VPL VD + G++WY+AK
Sbjct  836  IVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

327) polA in NC_003210


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  686 bits (2595),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 438/885 (50%), Positives = 645/885 (73%), Gaps = 20/885 (2%)

Query  2    NKLVLIDGNSIANRAFYAL----PLLNNDKGVYTNAVYGFAMMLMNVLEKEKPSHVLVAF  57
            NKL+LIDG+S+A RAF+AL      ++N+ G+ TNA+YGF +ML +++ + +P+HVLVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  58   DAGKTTFRHTTFKGYKGGRQKTPSELSEQFPFIRELLTAYDIPQYELANYEADDIIGTLT  117
            DAGKTTFR   + +YK+GR KTP E+ EQF++IRE+LTA +I+ YEL +YEADDIIGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  118  KKAEADGM--EVAIITGDRDLTQLASEKTTVYITKKGIADMETNTPETLKEKYNLTPEQI  175
            K AE   +  +V+I++GD+DL QL+ E+T V I+KKG+A+ E  TP  L EK  LTP+Q+
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  176  IDMKGLMGDSSDNIPGIPGVGEKTALKLLHEFGGTVESVLEHAEEISGkklkekvlenke  235
            ID+K+LMGD SDNIPG+  +GEKT+LKLLHEFG ++E++ EH + +   K+KE+++++++
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFG-SLEGIYEHIDGFKTSKMKENLINDRD  243

Query  236  lAILSKELATINVDSPIECTVESTKYDGYQTEKVIPLLKEMNFTTLLKNIEGDTPeeske  295
             A+LSK LATIN  SPI   ++   Y+G +   +  +  EM+F  L K + ++ P+E+  
Sbjct  244  QAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEPVA  303

Query  296  lkelsFEIVTELKEQHFGGKTALYVELENDNYHTANFIGLTVHSSQGTYFFTKETAESSE  355
            +    ++ VT++  + F++   +Y E   DNYH   +IG++   ++  Y  T  +  +++
Sbjct  304  VIS--YQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLATD  361

Query  356  AFRKWVESDQTKVVYDAKKTIVAMNRIGLAISGITFDIMLASYLLNPSDSIDDFTSVAVR  415
            +F++    ++    YD K++ V ++++G+ + + ++D  LA+YLL+  +  ++++++A  
Sbjct  362  SFKQ--VFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NELSTIA--  416

Query  416  HDYTEV--ETDEAVYGKGAKRSTPEESIVAAHLARKAVAIADLEKRLVDDLEKNEQLALM  473
            + +T++  E D++VYGKGAKR+ P+  ++  HLARK   + D   +++D L  +EQL L 
Sbjct  417  RIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLY  476

Query  474  EDLELPLTFVLAEMEMQGVSVDTDRLEDMKVELGGRLKTLEASIHSLAGEEFNINSPKQL  533
            +++ELPL+ VLA ME++G+ V+   L+DM  +    + +L   I  +AG+EFNINSPKQL
Sbjct  477  QNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQL  536

Query  534  GVILFEKLELP--PVKKTKTGYSTAADVLESLSGKHAIIDEILLYRQLGKIQSTYIEGLL  591
            G ILFEK++LP    KKTKTGYSTA DVLE L+   +I+  IL YRQ+ K+QSTY+ GL 
Sbjct  537  GSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQ  596

Query  592  KVTDKETHKVHTRFNQTLTQTGRLSSVDPNLQNIPIRLEEGRKIRQVFVPSKPGWKMFSA  651
                 +  K+HTR+ Q LTQTGRLSSVDPNLQNIPIRLE+GR IR+ F PS  +  ++S+
Sbjct  597  DYILADG-KIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSS  655

Query  652  DYSQVELRVLAHISEDENLIYAFKHDYDIHTKTAMDVFHVEKE-EVDSLMRRQAKAVNFG  710
            DYSQ+ELRVLAHIS DE+LI AF+++ DIHT TAM VF ++K  +V +  RR+AKAVNFG
Sbjct  656  DYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFG  715

Query  711  IVYGISDYGLSQNLGITRKEAKDFIDRYFVSYPAVKEYMQDIVRFAKEKGYVETILHRRR  770
            IVYGISD+GLS+NLGITRK++K +ID YF  YP++K YM+++VR AK+KGYVET++ RRR
Sbjct  716  IVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRR  775

Query  771  YIPEIVSRNFNVRGFAERTAMNTPIQGSAADIIKKAMILMSERLVSEKLEAKLLLQVHDE  830
             +P+I SRNFNVR+FAERTA+N+PIQGSAADI+K AMI +   L +  + AK+LLQVHDE
Sbjct  776  ELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDE  835

Query  831  LIFEAPEAEIAKLEEIVPDVMENAVELSVPLKVDSAFGDTWYDAK  875
            +++E P+ E++ +  +V D ME AV+L+VPL VD + G++WY+AK
Sbjct  836  IVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

328) LMLG_1764 in NC_017547


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  686 bits (2595),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 438/885 (50%), Positives = 645/885 (73%), Gaps = 20/885 (2%)

Query  2    NKLVLIDGNSIANRAFYAL----PLLNNDKGVYTNAVYGFAMMLMNVLEKEKPSHVLVAF  57
            NKL+LIDG+S+A RAF+AL      ++N+ G+ TNA+YGF +ML +++ + +P+HVLVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  58   DAGKTTFRHTTFKGYKGGRQKTPSELSEQFPFIRELLTAYDIPQYELANYEADDIIGTLT  117
            DAGKTTFR   + +YK+GR KTP E+ EQF++IRE+LTA +I+ YEL +YEADDIIGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  118  KKAEADGM--EVAIITGDRDLTQLASEKTTVYITKKGIADMETNTPETLKEKYNLTPEQI  175
            K AE   +  +V+I++GD+DL QL+ E+T V I+KKG+A+ E  TP  L EK  LTP+Q+
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  176  IDMKGLMGDSSDNIPGIPGVGEKTALKLLHEFGGTVESVLEHAEEISGkklkekvlenke  235
            ID+K+LMGD SDNIPG+  +GEKT+LKLLHEFG ++E++ EH + +   K+KE+++++++
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFG-SLEGIYEHIDGFKTSKMKENLINDRD  243

Query  236  lAILSKELATINVDSPIECTVESTKYDGYQTEKVIPLLKEMNFTTLLKNIEGDTPeeske  295
             A+LSK LATIN  SPI   ++   Y+G +   +  +  EM+F  L K + ++ P+E+  
Sbjct  244  QAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEPVA  303

Query  296  lkelsFEIVTELKEQHFGGKTALYVELENDNYHTANFIGLTVHSSQGTYFFTKETAESSE  355
            +    ++ VT++  + F++   +Y E   DNYH   +IG++   ++  Y  T  +  +++
Sbjct  304  VIS--YQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLATD  361

Query  356  AFRKWVESDQTKVVYDAKKTIVAMNRIGLAISGITFDIMLASYLLNPSDSIDDFTSVAVR  415
            +F++    ++    YD K++ V ++++G+ + + ++D  LA+YLL+  +  ++++++A  
Sbjct  362  SFKQ--VFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NELSTIA--  416

Query  416  HDYTEV--ETDEAVYGKGAKRSTPEESIVAAHLARKAVAIADLEKRLVDDLEKNEQLALM  473
            + +T++  E D++VYGKGAKR+ P+  ++  HLARK   + D   +++D L  +EQL L 
Sbjct  417  RIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLY  476

Query  474  EDLELPLTFVLAEMEMQGVSVDTDRLEDMKVELGGRLKTLEASIHSLAGEEFNINSPKQL  533
            +++ELPL+ VLA ME++G+ V+   L+DM  +    + +L   I  +AG+EFNINSPKQL
Sbjct  477  QNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQL  536

Query  534  GVILFEKLELP--PVKKTKTGYSTAADVLESLSGKHAIIDEILLYRQLGKIQSTYIEGLL  591
            G ILFEK++LP    KKTKTGYSTA DVLE L+   +I+  IL YRQ+ K+QSTY+ GL 
Sbjct  537  GSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQ  596

Query  592  KVTDKETHKVHTRFNQTLTQTGRLSSVDPNLQNIPIRLEEGRKIRQVFVPSKPGWKMFSA  651
                 +  K+HTR+ Q LTQTGRLSSVDPNLQNIPIRLE+GR IR+ F PS  +  ++S+
Sbjct  597  DYILADG-KIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSS  655

Query  652  DYSQVELRVLAHISEDENLIYAFKHDYDIHTKTAMDVFHVEKE-EVDSLMRRQAKAVNFG  710
            DYSQ+ELRVLAHIS DE+LI AF+++ DIHT TAM VF ++K  +V +  RR+AKAVNFG
Sbjct  656  DYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFG  715

Query  711  IVYGISDYGLSQNLGITRKEAKDFIDRYFVSYPAVKEYMQDIVRFAKEKGYVETILHRRR  770
            IVYGISD+GLS+NLGITRK++K +ID YF  YP++K YM+++VR AK+KGYVET++ RRR
Sbjct  716  IVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRR  775

Query  771  YIPEIVSRNFNVRGFAERTAMNTPIQGSAADIIKKAMILMSERLVSEKLEAKLLLQVHDE  830
             +P+I SRNFNVR+FAERTA+N+PIQGSAADI+K AMI +   L +  + AK+LLQVHDE
Sbjct  776  ELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDE  835

Query  831  LIFEAPEAEIAKLEEIVPDVMENAVELSVPLKVDSAFGDTWYDAK  875
            +++E P+ E++ +  +V D ME AV+L+VPL VD + G++WY+AK
Sbjct  836  IVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

329) LMKG_00643 in NC_017546


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  686 bits (2595),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 438/885 (50%), Positives = 645/885 (73%), Gaps = 20/885 (2%)

Query  2    NKLVLIDGNSIANRAFYAL----PLLNNDKGVYTNAVYGFAMMLMNVLEKEKPSHVLVAF  57
            NKL+LIDG+S+A RAF+AL      ++N+ G+ TNA+YGF +ML +++ + +P+HVLVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  58   DAGKTTFRHTTFKGYKGGRQKTPSELSEQFPFIRELLTAYDIPQYELANYEADDIIGTLT  117
            DAGKTTFR   + +YK+GR KTP E+ EQF++IRE+LTA +I+ YEL +YEADDIIGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  118  KKAEADGM--EVAIITGDRDLTQLASEKTTVYITKKGIADMETNTPETLKEKYNLTPEQI  175
            K AE   +  +V+I++GD+DL QL+ E+T V I+KKG+A+ E  TP  L EK  LTP+Q+
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  176  IDMKGLMGDSSDNIPGIPGVGEKTALKLLHEFGGTVESVLEHAEEISGkklkekvlenke  235
            ID+K+LMGD SDNIPG+  +GEKT+LKLLHEFG ++E++ EH + +   K+KE+++++++
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFG-SLEGIYEHIDGFKTSKMKENLINDRD  243

Query  236  lAILSKELATINVDSPIECTVESTKYDGYQTEKVIPLLKEMNFTTLLKNIEGDTPeeske  295
             A+LSK LATIN  SPI   ++   Y+G +   +  +  EM+F  L K + ++ P+E+  
Sbjct  244  QAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEPVA  303

Query  296  lkelsFEIVTELKEQHFGGKTALYVELENDNYHTANFIGLTVHSSQGTYFFTKETAESSE  355
            +    ++ VT++  + F++   +Y E   DNYH   +IG++   ++  Y  T  +  +++
Sbjct  304  VIS--YQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLATD  361

Query  356  AFRKWVESDQTKVVYDAKKTIVAMNRIGLAISGITFDIMLASYLLNPSDSIDDFTSVAVR  415
            +F++    ++    YD K++ V ++++G+ + + ++D  LA+YLL+  +  ++++++A  
Sbjct  362  SFKQ--VFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NELSTIA--  416

Query  416  HDYTEV--ETDEAVYGKGAKRSTPEESIVAAHLARKAVAIADLEKRLVDDLEKNEQLALM  473
            + +T++  E D++VYGKGAKR+ P+  ++  HLARK   + D   +++D L  +EQL L 
Sbjct  417  RIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLY  476

Query  474  EDLELPLTFVLAEMEMQGVSVDTDRLEDMKVELGGRLKTLEASIHSLAGEEFNINSPKQL  533
            +++ELPL+ VLA ME++G+ V+   L+DM  +    + +L   I  +AG+EFNINSPKQL
Sbjct  477  QNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQL  536

Query  534  GVILFEKLELP--PVKKTKTGYSTAADVLESLSGKHAIIDEILLYRQLGKIQSTYIEGLL  591
            G ILFEK++LP    KKTKTGYSTA DVLE L+   +I+  IL YRQ+ K+QSTY+ GL 
Sbjct  537  GSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQ  596

Query  592  KVTDKETHKVHTRFNQTLTQTGRLSSVDPNLQNIPIRLEEGRKIRQVFVPSKPGWKMFSA  651
                 +  K+HTR+ Q LTQTGRLSSVDPNLQNIPIRLE+GR IR+ F PS  +  ++S+
Sbjct  597  DYILADG-KIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSS  655

Query  652  DYSQVELRVLAHISEDENLIYAFKHDYDIHTKTAMDVFHVEKE-EVDSLMRRQAKAVNFG  710
            DYSQ+ELRVLAHIS DE+LI AF+++ DIHT TAM VF ++K  +V +  RR+AKAVNFG
Sbjct  656  DYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFG  715

Query  711  IVYGISDYGLSQNLGITRKEAKDFIDRYFVSYPAVKEYMQDIVRFAKEKGYVETILHRRR  770
            IVYGISD+GLS+NLGITRK++K +ID YF  YP++K YM+++VR AK+KGYVET++ RRR
Sbjct  716  IVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRR  775

Query  771  YIPEIVSRNFNVRGFAERTAMNTPIQGSAADIIKKAMILMSERLVSEKLEAKLLLQVHDE  830
             +P+I SRNFNVR+FAERTA+N+PIQGSAADI+K AMI +   L +  + AK+LLQVHDE
Sbjct  776  ELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDE  835

Query  831  LIFEAPEAEIAKLEEIVPDVMENAVELSVPLKVDSAFGDTWYDAK  875
            +++E P+ E++ +  +V D ME AV+L+VPL VD + G++WY+AK
Sbjct  836  IVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

330) LMOG_00130 in NC_017545


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  686 bits (2595),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 438/885 (50%), Positives = 645/885 (73%), Gaps = 20/885 (2%)

Query  2    NKLVLIDGNSIANRAFYAL----PLLNNDKGVYTNAVYGFAMMLMNVLEKEKPSHVLVAF  57
            NKL+LIDG+S+A RAF+AL      ++N+ G+ TNA+YGF +ML +++ + +P+HVLVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  58   DAGKTTFRHTTFKGYKGGRQKTPSELSEQFPFIRELLTAYDIPQYELANYEADDIIGTLT  117
            DAGKTTFR   + +YK+GR KTP E+ EQF++IRE+LTA +I+ YEL +YEADDIIGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  118  KKAEADGM--EVAIITGDRDLTQLASEKTTVYITKKGIADMETNTPETLKEKYNLTPEQI  175
            K AE   +  +V+I++GD+DL QL+ E+T V I+KKG+A+ E  TP  L EK  LTP+Q+
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  176  IDMKGLMGDSSDNIPGIPGVGEKTALKLLHEFGGTVESVLEHAEEISGkklkekvlenke  235
            ID+K+LMGD SDNIPG+  +GEKT+LKLLHEFG ++E++ EH + +   K+KE+++++++
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFG-SLEGIYEHIDGFKTSKMKENLINDRD  243

Query  236  lAILSKELATINVDSPIECTVESTKYDGYQTEKVIPLLKEMNFTTLLKNIEGDTPeeske  295
             A+LSK LATIN  SPI   ++   Y+G +   +  +  EM+F  L K + ++ P+E+  
Sbjct  244  QAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEPVA  303

Query  296  lkelsFEIVTELKEQHFGGKTALYVELENDNYHTANFIGLTVHSSQGTYFFTKETAESSE  355
            +    ++ VT++  + F++   +Y E   DNYH   +IG++   ++  Y  T  +  +++
Sbjct  304  VIS--YQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLATD  361

Query  356  AFRKWVESDQTKVVYDAKKTIVAMNRIGLAISGITFDIMLASYLLNPSDSIDDFTSVAVR  415
            +F++    ++    YD K++ V ++++G+ + + ++D  LA+YLL+  +  ++++++A  
Sbjct  362  SFKQ--VFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NELSTIA--  416

Query  416  HDYTEV--ETDEAVYGKGAKRSTPEESIVAAHLARKAVAIADLEKRLVDDLEKNEQLALM  473
            + +T++  E D++VYGKGAKR+ P+  ++  HLARK   + D   +++D L  +EQL L 
Sbjct  417  RIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLY  476

Query  474  EDLELPLTFVLAEMEMQGVSVDTDRLEDMKVELGGRLKTLEASIHSLAGEEFNINSPKQL  533
            +++ELPL+ VLA ME++G+ V+   L+DM  +    + +L   I  +AG+EFNINSPKQL
Sbjct  477  QNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQL  536

Query  534  GVILFEKLELP--PVKKTKTGYSTAADVLESLSGKHAIIDEILLYRQLGKIQSTYIEGLL  591
            G ILFEK++LP    KKTKTGYSTA DVLE L+   +I+  IL YRQ+ K+QSTY+ GL 
Sbjct  537  GSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQ  596

Query  592  KVTDKETHKVHTRFNQTLTQTGRLSSVDPNLQNIPIRLEEGRKIRQVFVPSKPGWKMFSA  651
                 +  K+HTR+ Q LTQTGRLSSVDPNLQNIPIRLE+GR IR+ F PS  +  ++S+
Sbjct  597  DYILADG-KIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSS  655

Query  652  DYSQVELRVLAHISEDENLIYAFKHDYDIHTKTAMDVFHVEKE-EVDSLMRRQAKAVNFG  710
            DYSQ+ELRVLAHIS DE+LI AF+++ DIHT TAM VF ++K  +V +  RR+AKAVNFG
Sbjct  656  DYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFG  715

Query  711  IVYGISDYGLSQNLGITRKEAKDFIDRYFVSYPAVKEYMQDIVRFAKEKGYVETILHRRR  770
            IVYGISD+GLS+NLGITRK++K +ID YF  YP++K YM+++VR AK+KGYVET++ RRR
Sbjct  716  IVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRR  775

Query  771  YIPEIVSRNFNVRGFAERTAMNTPIQGSAADIIKKAMILMSERLVSEKLEAKLLLQVHDE  830
             +P+I SRNFNVR+FAERTA+N+PIQGSAADI+K AMI +   L +  + AK+LLQVHDE
Sbjct  776  ELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDE  835

Query  831  LIFEAPEAEIAKLEEIVPDVMENAVELSVPLKVDSAFGDTWYDAK  875
            +++E P+ E++ +  +V D ME AV+L+VPL VD + G++WY+AK
Sbjct  836  IVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

331) polA in NC_013766


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  686 bits (2595),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 438/885 (50%), Positives = 645/885 (73%), Gaps = 20/885 (2%)

Query  2    NKLVLIDGNSIANRAFYAL----PLLNNDKGVYTNAVYGFAMMLMNVLEKEKPSHVLVAF  57
            NKL+LIDG+S+A RAF+AL      ++N+ G+ TNA+YGF +ML +++ + +P+HVLVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  58   DAGKTTFRHTTFKGYKGGRQKTPSELSEQFPFIRELLTAYDIPQYELANYEADDIIGTLT  117
            DAGKTTFR   + +YK+GR KTP E+ EQF++IRE+LTA +I+ YEL +YEADDIIGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  118  KKAEADGM--EVAIITGDRDLTQLASEKTTVYITKKGIADMETNTPETLKEKYNLTPEQI  175
            K AE   +  +V+I++GD+DL QL+ E+T V I+KKG+A+ E  TP  L EK  LTP+Q+
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  176  IDMKGLMGDSSDNIPGIPGVGEKTALKLLHEFGGTVESVLEHAEEISGkklkekvlenke  235
            ID+K+LMGD SDNIPG+  +GEKT+LKLLHEFG ++E++ EH + +   K+KE+++++++
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFG-SLEGIYEHIDGFKTSKMKENLINDRD  243

Query  236  lAILSKELATINVDSPIECTVESTKYDGYQTEKVIPLLKEMNFTTLLKNIEGDTPeeske  295
             A+LSK LATIN  SPI   ++   Y+G +   +  +  EM+F  L K + ++ P+E+  
Sbjct  244  QAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEPVA  303

Query  296  lkelsFEIVTELKEQHFGGKTALYVELENDNYHTANFIGLTVHSSQGTYFFTKETAESSE  355
            +    ++ VT++  + F++   +Y E   DNYH   +IG++   ++  Y  T  +  +++
Sbjct  304  VIS--YQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLATD  361

Query  356  AFRKWVESDQTKVVYDAKKTIVAMNRIGLAISGITFDIMLASYLLNPSDSIDDFTSVAVR  415
            +F++    ++    YD K++ V ++++G+ + + ++D  LA+YLL+  +  ++++++A  
Sbjct  362  SFKQ--VFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NELSTIA--  416

Query  416  HDYTEV--ETDEAVYGKGAKRSTPEESIVAAHLARKAVAIADLEKRLVDDLEKNEQLALM  473
            + +T++  E D++VYGKGAKR+ P+  ++  HLARK   + D   +++D L  +EQL L 
Sbjct  417  RIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLY  476

Query  474  EDLELPLTFVLAEMEMQGVSVDTDRLEDMKVELGGRLKTLEASIHSLAGEEFNINSPKQL  533
            +++ELPL+ VLA ME++G+ V+   L+DM  +    + +L   I  +AG+EFNINSPKQL
Sbjct  477  QNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQL  536

Query  534  GVILFEKLELP--PVKKTKTGYSTAADVLESLSGKHAIIDEILLYRQLGKIQSTYIEGLL  591
            G ILFEK++LP    KKTKTGYSTA DVLE L+   +I+  IL YRQ+ K+QSTY+ GL 
Sbjct  537  GSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQ  596

Query  592  KVTDKETHKVHTRFNQTLTQTGRLSSVDPNLQNIPIRLEEGRKIRQVFVPSKPGWKMFSA  651
                 +  K+HTR+ Q LTQTGRLSSVDPNLQNIPIRLE+GR IR+ F PS  +  ++S+
Sbjct  597  DYILADG-KIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSS  655

Query  652  DYSQVELRVLAHISEDENLIYAFKHDYDIHTKTAMDVFHVEKE-EVDSLMRRQAKAVNFG  710
            DYSQ+ELRVLAHIS DE+LI AF+++ DIHT TAM VF ++K  +V +  RR+AKAVNFG
Sbjct  656  DYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFG  715

Query  711  IVYGISDYGLSQNLGITRKEAKDFIDRYFVSYPAVKEYMQDIVRFAKEKGYVETILHRRR  770
            IVYGISD+GLS+NLGITRK++K +ID YF  YP++K YM+++VR AK+KGYVET++ RRR
Sbjct  716  IVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRR  775

Query  771  YIPEIVSRNFNVRGFAERTAMNTPIQGSAADIIKKAMILMSERLVSEKLEAKLLLQVHDE  830
             +P+I SRNFNVR+FAERTA+N+PIQGSAADI+K AMI +   L +  + AK+LLQVHDE
Sbjct  776  ELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDE  835

Query  831  LIFEAPEAEIAKLEEIVPDVMENAVELSVPLKVDSAFGDTWYDAK  875
            +++E P+ E++ +  +V D ME AV+L+VPL VD + G++WY+AK
Sbjct  836  IVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

332) polA in NC_003212


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  686 bits (2594),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 433/885 (49%), Positives = 647/885 (74%), Gaps = 20/885 (2%)

Query  2    NKLVLIDGNSIANRAFYAL----PLLNNDKGVYTNAVYGFAMMLMNVLEKEKPSHVLVAF  57
            NKL+LIDG+S+A RAF+AL      ++N+ G+ TNA+YGF +ML +++ + +P+HVLVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  58   DAGKTTFRHTTFKGYKGGRQKTPSELSEQFPFIRELLTAYDIPQYELANYEADDIIGTLT  117
            DAGKTTFR   + +YK+GR KTP E+ EQF++IRE+LTA +I+ YEL +YEADDIIGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  118  KKAEADGM--EVAIITGDRDLTQLASRKTTVYITKKGIADMETNTPETLKEKYDLTPSQI  175
            K AE   +  +V+I++GD+DL QL+  +T V I+KKG+A+ E  TP  L EK +LTP+Q+
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  176  IDMKGLMGDSSDNIPGIPGVGEKTALKLLHEFGGTVESVLEHAEEISGkklkekvlenke  235
            ID+K+LMGD SDNIPG+  +GEKT+LKLLHEFG ++E++ EH + +   K+KE+++++++
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFG-SLEGIYEHIDGFKTSKMKENLINDRD  243

Query  236  lAILSKELATINVDSPIECTVESTKYDGYQTEKVIPLLKEMNFTTLLKNIEGDTAEEAKE  295
             A+LSK LATIN  SPI   ++   Y+G +   +  +  EM+F  L K + ++ ++E+  
Sbjct  244  QAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEPVA  303

Query  296  LKELSFEIVTELKEQHFGGKTALYVELENDNYHTANFIGLTVHSSQGTYFFTKETAEKSA  355
            +  +S++ VT++  + F++   +Y E   DNYH   +IG++   ++  Y  T  +   + 
Sbjct  304  V--ISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLATD  361

Query  356  VFRNWVESDETKVVYDAKKTMVAMNRIGFAIKGVTFDIMLASYLLNPSDSIDDFTSVAVR  415
             F++    +     YD K++ V ++++G+ + + ++D  LA+YLL+  +  ++++++A  
Sbjct  362  SFKQ--VFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NELSTIA--  416

Query  416  HDYTEV--ETDEAIYGKGAKRSTPEENIVAAHLARKAVAIAELEKRLVDDLEENEQLALM  473
            + +T++  E D+++YGKGAKR+ P+ +++  HLARK   + +   +++D L  +EQL L 
Sbjct  417  RIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLY  476

Query  474  EDLELPLTFVLAQMEMQGVSVDTKRLENMKVELAGRLKTLEESIHSLAGEEFNINSPKQL  533
            +++ELPL+ VLA+ME++G+ V+   L++M  +    + +L + I  +AG+EFNINSPKQL
Sbjct  477  QNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQL  536

Query  534  GVILFEKLELP--PVKKTKTGYSTAADVLESLSGKHAIIDEILLYRQLGKIQSTYIEGLL  591
            G ILFEK++LP    KKTKTGYSTA DVLE L+   +I+  IL YRQ+ K+QSTY+ GL 
Sbjct  537  GSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQ  596

Query  592  KVTDKETHKVHTRFNQTLTQTGRLSSVDPNLQNIPIRLEEGRKIRQVFVPSKPGWKMFSA  651
                 +  K+HTR+ Q LTQTGRLSSVDPNLQNIPIRLE+GR IR+ F PS  +  ++S+
Sbjct  597  DYILADG-KIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSS  655

Query  652  DYSQVELRVLAHISEDENLIYAFKHDYDIHTKTAMDVFHVEQD-EVDSLMRRQAKAVNFG  710
            DYSQ+ELRVLAHIS DE+LI AF+++ DIHT TAM VF +++  +V +  RR+AKAVNFG
Sbjct  656  DYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFG  715

Query  711  IVYGISDYGLSQNLGITRKEAKDFIDRYFVSYPAVKEYMQDIVRFAKEKGYVETILHRRR  770
            IVYGISD+GLS+NLGITRK++K +ID YF  YP++K YM+++VR AK+KGYVET++ RRR
Sbjct  716  IVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRR  775

Query  771  YIPEIVSRNFNVRGFAERTAMNTPIQGSAADIIKKAMILMSERLKSENLEAKLLLQVHDE  830
             +P+I SRNFNVR+FAERTA+N+PIQGSAADI+K AMI +   L++  + AK+LLQVHDE
Sbjct  776  ELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDE  835

Query  831  LIFEAPEAEIAKLEEIVPDVMENAVELSVPLKVDSAFGDTWYDAK  875
            +++E P+ E++ +  +V D ME AV+L+VPL VD + G++WY+AK
Sbjct  836  IVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

333) polA in NC_008555


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  685 bits (2591),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 439/885 (50%), Positives = 642/885 (73%), Gaps = 20/885 (2%)

Query  2    NKLVLIDGNSIANRAFYAL----PLLNNDKGVYTNAVYGFAMMLMNVLEKEKPSHVLVAF  57
            NKL+LIDG+S+A RAF+AL      ++N+ G+ TNA+YGF +ML +++ + +P+HVLVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  58   DAGKTTFRHTTFKGYKGGRQKTPSELSEQFPFIRELLTAYDIPQYELANYEADDIIGTLT  117
            DAGKTTFR   + +YK+GR KTP E+ EQF++IRE+LTA +I+ YEL +YEADDIIGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  118  KQAEADGL--EVAIITGDRDLTQLASEKTTVYITKKGIADMETNTPETLKEKYNLTPTQI  175
            K AE   +  +V+I++GD+DL QL+ E+T V I+KKG+A+ E  TP  L EK  LTP Q+
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  176  IDMKGLMGDSSDNIPGIPGVGEKTALKLLHEFGGTVESVLEHAEEISGkklkekvlenke  235
            ID+K+LMGD SDNIPG+  +GEKT+LKLLHEFG ++E++ EH + +   K+KE+++++++
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFG-SLEGIYEHIDGFKTSKMKENLINDRD  243

Query  236  lAVLSKELATINVNSPIECTVESTKYDGYQTEKVIPLLKEMNFTTLLKNIEGGAPEEVKE  295
             A LSK LATIN  SPI   ++   Y+G +   +  +  EM+F  L K + +  P+E   
Sbjct  244  QAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEPVA  303

Query  296  LKELSYEIVTELKEKHFGGKTALYVELENDNYHTANFIGLAIHSDQGTYFFTKETAENSV  355
            +  +SY+ VT++    F++   +Y E   DNYH   +IG+A   ++  Y  T  +   + 
Sbjct  304  V--ISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLATD  361

Query  356  SFREWVESAQTKVVYDAKKTMVAMNRMGFAISGITFDIMLASYLLNPSDSIDDFTSVAVR  415
            SF++  + + +   YD K++ V ++++G+ + + ++D  LA+YLL+  +  ++++++A  
Sbjct  362  SFKQVFQKPIA--TYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NELSTIA--  416

Query  416  HDYTEV--ETDEAVYGKGAKRSTPEESIVAGHLARKAVAIAELEKRLVDDLEKNEQLALM  473
            + +T++  E D++VYGKGAKR+ P+  ++  HLARK   + +   +++D L  +EQL L 
Sbjct  417  RIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLY  476

Query  474  EDLELPLTFVLAQMEMQGVSVDTERLENMKVELAGRLKTLETSIHSLAGEEFNINSPKQL  533
            +++ELPL+ VLA+ME++G+ V+   L++M  +    + +L   I  +AG+EFNINSPKQL
Sbjct  477  QNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQL  536

Query  534  GVILFEKLELP--PVKKTKTGYSTAADVLESLSGKHDIIDEILLYRQLGKIQSTYIEGLL  591
            G ILFEK++LP    KKTKTGYSTA DVLE L+    I+  IL YRQ+ K+QSTY+ GL 
Sbjct  537  GSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQ  596

Query  592  KVTDKETHKVHTRFNQTLTQTGRLSSVDPNLQNIPIRLEEGRKIRQVFVPSKPGWKIFSA  651
                 +  K+HTR+ Q LTQTGRLSSVDPNLQNIPIRLE+GR IR+ F PS  +  ++S+
Sbjct  597  DYILADG-KIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSS  655

Query  652  DYSQVELRVLAHISEDENLIYAFKHDYDIHTKTAMDVFHVEQE-EVDSLMRRQAKAVNFG  710
            DYSQ+ELRVLAHIS DE+LI AF+++ DIHT TAM VF +++  +V +  RR+AKAVNFG
Sbjct  656  DYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFG  715

Query  711  IVYGISDYGLSQNLGITRKDAKDFIDRYFVSYPAVKEYMHDIVRFAKEKGYVETILHRRR  770
            IVYGISD+GLS+NLGITRK++K +ID YF  YP++K YM+++VR AK+KGYVET++ RRR
Sbjct  716  IVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRR  775

Query  771  YIPEIVSRNFNVRGFAERTAMNTPIQGSAADIIKKAMILMSERLESEQLEAKLLLQVHDE  830
             +P+I SRNFNVR+FAERTA+N+PIQGSAADI+K AMI +   L++  + AK+LLQVHDE
Sbjct  776  ELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDE  835

Query  831  LIFEAPEAEIAKLEEIVPDVMENAVELSVPLKVDSAFGDTWYDAK  875
            +++E P+ E++ +  +V D ME AV+L+VPL VD + G++WY+AK
Sbjct  836  IVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

334) polA in NC_018592


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  683 bits (2582),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 438/885 (50%), Positives = 643/885 (73%), Gaps = 20/885 (2%)

Query  12   NKLVLIDGNSIANRAFYAL----PLLNNDKGVYTNAVYGFAMMLMNVLEKEKPSHVLVAF  67
            NKL+LIDG+S+A RAF+AL      ++N+ G+ TNA+YGF +ML +++ + +P+HVLVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  68   DAGKTTFRHTTFKGYKGGRQKTPSELSEQFPFIRELLTAYDIPQYELANYEADDIIGTLT  127
            DAGKTTFR   + +YK+GR KTP E+ EQF++IRE+LTA +I+ YEL +YEADDIIGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  128  KKAEADGM--EVAIITGDRDLTQLASEKTTVYITKKGIADMETNTPETLKEKYNLTPEQI  185
            K AE   +  +V+I++GD+DL QL+ E+T V I+KKG+A+ E  TP  L EK  LTP+Q+
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  186  IDMKGLMGDSSDNIPGIPGVGEKTALKLLHEFGGTVESVLEHAEEISGkklkekvlenke  245
            ID+K+LMGD SDNIPG+  +GEKT+LKLLHEFG ++E++ EH + +   K+KE+++++++
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFG-SLEGIYEHIDGFKTSKMKENLINDRD  243

Query  246  lAILSKELATINVDSPIECTVESTKYDGYQTEKVIPLLKEMNFTTLLKNIEGDTPeeske  305
             A+LSK LATIN  SPI   ++   Y+G +   +  +  EM+F  L K + ++ P+E+  
Sbjct  244  QAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEPVA  303

Query  306  lkelffeIVTELKEQHFGGKTALYVELENDNYHTANFIGLTVHSSQGTYFFTKETAESSE  365
            +       VT++  + F++   +Y E   DNYH   +IG++   ++  Y  T  +  +++
Sbjct  304  VISYQE--VTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLATD  361

Query  366  AFRKWVESDQTKVVYDAKKTIVAMNRIGLAISGITFDIMLASYLLNPSDSIDDFTSVAVR  425
            +F++    ++    YD K++ V ++++G+ + + ++D  LA+YLL+  +  ++++++A  
Sbjct  362  SFKQ--VFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NELSTIA--  416

Query  426  HDYTEV--ETDEAVYGKGAKRSTPEESIVAAHLARKAVAIADLEKRLVDDLEKNEQLALM  483
            + +T++  E D++VYGKGAKR+ P+  ++  HLARK   + D   +++D L  +EQL L 
Sbjct  417  RIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLY  476

Query  484  EDLELPLTFVLAEMEMQGVSVDTDRLEDMKVELGGRLKTLEASIHSLAGEEFNINSPKQL  543
            +++ELPL+ VLA ME++G+ V+   L+DM  +    + +L   I  +AG+EFNINSPKQL
Sbjct  477  QNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQL  536

Query  544  GVILFEKLELP--PVKKTKTGYSTAADVLESLSGKHAIIDEILLYRQLGKIQSTYIEGLL  601
            G ILFEK++LP    KKTKTGYSTA DVLE L+   +I+  IL YRQ+ K+QSTY+ GL 
Sbjct  537  GSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQ  596

Query  602  KVTDKETHKVHTRFNQTLTQTGRLSSVDPNLQNIPIRLEEGRKIRQVFVPSKPGWKMFSA  661
                 +  K+HTR+ Q LTQTGRLSSVDPNLQNIPIRLE+GR IR+ F PS  +  ++S+
Sbjct  597  DYILADG-KIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSS  655

Query  662  DYSQVELRVLAHISEDENLIYAFKHDYDIHTKTAMDVFHVEKE-EVDSLMRRQAKAVNFG  720
            DYSQ+ELRVLAHIS DE+LI AF+++ DIHT TAM VF ++K  +V +  RR+AKAVNFG
Sbjct  656  DYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFG  715

Query  721  IVYGISDYGLSQNLGITRKEAKDFIDRYFVSYPAVKEYMQDIVRFAKEKGYVETILHRRR  780
            IVYGISD+GLS+NLGITRK++K +ID YF  YP++K YM+++VR AK+KGYVET++ RRR
Sbjct  716  IVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRR  775

Query  781  YIPEIVSRNFNVRGFAERTAMNTPIQGSAADIIKKAMILMSERLVSEKLEAKLLLQVHDE  840
             +P+I SRNFNVR+FAERTA+N+PIQGSAADI+K AMI +   L +  + AK+LLQVHDE
Sbjct  776  ELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDE  835

Query  841  LIFEAPEAEIAKLEEIVPDVMENAVELSVPLKVDSAFGDTWYDAK  885
            +++E P+ E++ +  +V D ME AV+L+VPL VD + G++WY+AK
Sbjct  836  IVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

335) LMRG_01402 in NC_017544


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  682 bits (2580),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 438/885 (50%), Positives = 643/885 (73%), Gaps = 20/885 (2%)

Query  2    NKLVLIDGNSIANRAFYAL----PLLNNDKGVYTNAVYGFAMMLMNVLEKEKPSHVLVAF  57
            NKL+LIDG+S+A RAF+AL      ++N+ G+ TNA+YGF +ML +++ + +P+HVLVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  58   DAGKTTFRHTTFKGYKGGRQKTPSELSEQFPFIRELLTAYDIPQYELANYEADDIIGTLT  117
            DAGKTTFR   + +YK+GR KTP E+ EQF++IRE+LTA +I+ YEL +YEADDIIGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  118  KKAEADGM--EVAIITGDRDLTQLASEKTTVYITKKGIADMETNTPETLKEKYNLTPEQI  175
            K AE   +  +V+I++GD+DL QL+ E+T V I+KKG+A+ E  TP  L EK  LTP+Q+
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  176  IDMKGLMGDSSDNIPGIPGVGEKTALKLLHEFGGTVESVLEHAEEISGkklkekvlenke  235
            ID+K+LMGD SDNIPG+  +GEKT+LKLLHEFG ++E++ EH + +   K+KE+++++++
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFG-SLEGIYEHIDGFKTSKMKENLINDRD  243

Query  236  lAILSKELATINVDSPIECTVESTKYDGYQTEKVIPLLKEMNFTTLLKNIEGDTPeeske  295
             A+LSK LATIN  SPI   ++   Y+G +   +  +  EM+F  L K + ++ P+E+  
Sbjct  244  QAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEPVA  303

Query  296  lkelffeIVTELKEQHFGGKTALYVELENDNYHTANFIGLTVHSSQGTYFFTKETAESSE  355
            +       VT++  + F++   +Y E   DNYH   +IG++   ++  Y  T  +  +++
Sbjct  304  VISYQE--VTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLATD  361

Query  356  AFRKWVESDQTKVVYDAKKTIVAMNRIGLAISGITFDIMLASYLLNPSDSIDDFTSVAVR  415
            +F++    ++    YD K++ V ++++G+ + + ++D  LA+YLL+  +  ++++++A  
Sbjct  362  SFKQ--VFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NELSTIA--  416

Query  416  HDYTEV--ETDEAVYGKGAKRSTPEESIVAAHLARKAVAIADLEKRLVDDLEKNEQLALM  473
            + +T++  E D++VYGKGAKR+ P+  ++  HLARK   + D   +++D L  +EQL L 
Sbjct  417  RIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLY  476

Query  474  EDLELPLTFVLAEMEMQGVSVDTDRLEDMKVELGGRLKTLEASIHSLAGEEFNINSPKQL  533
            +++ELPL+ VLA ME++G+ V+   L+DM  +    + +L   I  +AG+EFNINSPKQL
Sbjct  477  QNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQL  536

Query  534  GVILFEKLELP--PVKKTKTGYSTAADVLESLSGKHAIIDEILLYRQLGKIQSTYIEGLL  591
            G ILFEK++LP    KKTKTGYSTA DVLE L+   +I+  IL YRQ+ K+QSTY+ GL 
Sbjct  537  GSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQ  596

Query  592  KVTDKETHKVHTRFNQTLTQTGRLSSVDPNLQNIPIRLEEGRKIRQVFVPSKPGWKMFSA  651
                 +  K+HTR+ Q LTQTGRLSSVDPNLQNIPIRLE+GR IR+ F PS  +  ++S+
Sbjct  597  DYILADG-KIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSS  655

Query  652  DYSQVELRVLAHISEDENLIYAFKHDYDIHTKTAMDVFHVEKE-EVDSLMRRQAKAVNFG  710
            DYSQ+ELRVLAHIS DE+LI AF+++ DIHT TAM VF ++K  +V +  RR+AKAVNFG
Sbjct  656  DYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFG  715

Query  711  IVYGISDYGLSQNLGITRKEAKDFIDRYFVSYPAVKEYMQDIVRFAKEKGYVETILHRRR  770
            IVYGISD+GLS+NLGITRK++K +ID YF  YP++K YM+++VR AK+KGYVET++ RRR
Sbjct  716  IVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRR  775

Query  771  YIPEIVSRNFNVRGFAERTAMNTPIQGSAADIIKKAMILMSERLVSEKLEAKLLLQVHDE  830
             +P+I SRNFNVR+FAERTA+N+PIQGSAADI+K AMI +   L +  + AK+LLQVHDE
Sbjct  776  ELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDE  835

Query  831  LIFEAPEAEIAKLEEIVPDVMENAVELSVPLKVDSAFGDTWYDAK  875
            +++E P+ E++ +  +V D ME AV+L+VPL VD + G++WY+AK
Sbjct  836  IVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

336) polA in NC_012121


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  682 bits (2580),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 422/887 (48%), Positives = 637/887 (72%), Gaps = 23/887 (2%)

Query  2    EKLVLIDGNSLSFRAFYAL----PLLTNRAGIHTNAVYGFAMLLEKIKKEEQPTNFLVAF  57
            +KL+LIDG+S++FRAF+AL      + N++G+HTNA+YGF ++L+ + K  +PT+ LVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  58   DAGKTTFRHETFGDYKGGRQKTPPELSEQFPLIRQLLDAYQIKHYELENYEADDIIGTLS  117
            DAGKTTFR E ++DYK+GR KTP E+ EQF+ IR++L A  I  YELE+YEADDIIGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  118  KEADKAGI--QTIIVTGDRDLTQLASDNVTIYYTKKGVTDVDHYTPEFIAEKYNGLKPSQ  175
            K A+++ +  +  IV+GD+DL QL+ +N  +  +KKGV++ +++TP ++ EK  GL P+Q
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEK-MGLTPNQ  183

Query  176  IIDMKGLMGDTSDNIPGIAGVGEKTAIKLLNQFETVENLYEHIDEVSGKKLKEKLENGQE  235
            +ID+K+LMGD SDNIPG++ +GEKT++KLL++F ++E +YEHID     K+KE+L N+++
Sbjct  184  FIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRD  243

Query  236  DAFMSKQLATIKRDSPIEVSLKDTKLPDDVDQTAKIDLFKELDFKQMLNQIDVSAEDKTE  295
            +AF+SK LATI+  SPI ++L D  + ++ D ++  +++ E+DF Q+ + +     +   
Sbjct  244  QAFLSKTLATINTASPITIGLDDI-VYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEPV  302

Query  296  EKREYEVEHNFENINFNDLSEASIHFEVDEGDYLTADILKFG-IQADGHFVVINAE--QI  352
                Y+   N     F+  +E  + FE   ++Y    I+ F+  +++  +   +      
Sbjct  303  AVISYQEVTNVSADLFS--AEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLAT  360

Query  353  NDYPELVEWLENDQTRKRVYDAKKTYAEAHRLNIDIKNVSFDIMLASYILDPSRSIDDVY  412
            + + ++       Q     YD K++     +L I++   S+D  LA+Y+L      +++ 
Sbjct  361  DSFKQVF------QKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NELS  413

Query  413  SVVHNYGQNYVAEEVNIYGKGRKRQIPEDEVLDTYIASILDAISESTPIMYDQLEEFNQL  472
            ++ + + +  + E+  +YGKG KR +P+ +VL   +A  +  + +S + M D+L   +QL
Sbjct  414  TIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQL  473

Query  473  DLFESLELPLARILGEMEELGIYTDVDELKEMEKEIQGKLDTLITRIHDAAGEDFNINSP  532
            DL++++ELPLA +L+ ME  GI  +   L++M  + +  +++L   I D AG++FNINSP
Sbjct  474  DLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSP  533

Query  533  KQLGVVLFENLKLP--VIKKTKTGYSTAVDVLEQLQGEHPIIDDILEYRQLSKLQSTYIE  590
            KQLG +LFE+++LP  + KKTKTGYSTAVDVLE+L    PI+  IL+YRQ++KLQSTY+ 
Sbjct  534  KQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVI  593

Query  591  GLQKVIQNDHRIHTHFNQTLAQTGRLSSVDPNLQNIPVRLEEGRRIRKAFKPAEPGNVIL  650
            GLQ  I  D +IHT++ Q L+QTGRLSSVDPNLQNIP+RLE+GR IRKAF P++ + V+L
Sbjct  594  GLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLL  653

Query  651  SADYSQIELRVLAHITQDESMIKAFREGHDIHTATAMKVFGVE-PDEVDSLMRRQAKAVN  709
            S+DYSQIELRVLAHI+ DE +I AF EG DIHT+TAM+VFG++ + +V +  RR+AKAVN
Sbjct  654  SSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVN  713

Query  710  FGIVYGISDYGLSQSLGITRKAAKQFIDDYLDSFPGVKQYMSDIVKDAKAKGYVETLLHR  769
            FGIVYGISD+GLS++LGITRK +K +ID Y++ +PG+K YM ++V++AK KGYVETL+ R
Sbjct  714  FGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKR  773

Query  770  RRYIPDITSRNFNRRSFAERTAMNTPIQGSAADIIKLAMVNFDKEIKNKDFHAHLLLQVH  829
            RR +PDI SRNFN RSFAERTA+N+PIQGSAADI+K+AM+N+DK ++  +F+A +LLQVH
Sbjct  774  RRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVH  833

Query  830  DelifelpeeeveAFSAFIEDIMDNAIDLDVPLQVDTNYGPTWYDAK  876
            DE+++E+P++E+ A+  ++ D M+ A+DL VPL VD + G +WY+AK
Sbjct  834  DEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

337) SSP1075 in NC_007350


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  682 bits (2580),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 418/891 (47%), Positives = 640/891 (72%), Gaps = 31/891 (3%)

Query  2    NKLILIDGNSLSFRAFYAL----PLLQNKAGIHTNAVYGFAMLLEKIIKEEQPTHFLVAF  57
            NKL+LIDG+S++FRAF+AL      ++N +G+HTNA+YGF ++L+ ++K  +PTH LVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  58   DAGKTTFRHEQYSEYKGGRQKTPPELSEQFPYVRQLLDAYQIKRYELDNYEADDIIGTLS  117
            DAGKTTFR E Y++YK+GR KTP E+ EQF+Y+R++L A  I  YEL++YEADDIIGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  118  KQANAEK--FETIIVTGDRDLTQLATDDVTIYYTKKGVTDVDHYTPEFIAEKYDGLVPNQ  175
            K A+     F+  IV+GD+DL QL+ ++  +  +KKGV++ +++TP ++ EK  GL PNQ
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEK-MGLTPNQ  183

Query  176  IIDMKGLMGDASDNIPGVAGVGEKTAIKLLKKFSTVENVYNHIEEVSGkklkeklensks  235
            +ID+K+LMGD SDNIPGV+ +GEKT++KLL  F+++E +Y+HI+     K+KE+L N + 
Sbjct  184  FIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRD  243

Query  236  DALMSKELATINCDSPIEVTLADTKLPESPDSTAKIDIFKKLEFKQLLDQVDVEGTHTSA  295
            +A++SK LATIN  SPI + L D  + ++PD ++  +++  ++F QL   +  +  + + 
Sbjct  244  QAFLSKTLATINTASPITIGLDDI-VYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEPV  302

Query  296  EELELEITSDFSNVDFNELSEATIHFELDGSNYLKDDILKFA------LYDGSNHVVIDA  349
              +  +  ++ S   F+  +E  + FE    NY ++ I+ FA      +Y +++  ++ +
Sbjct  303  AVISYQEVTNVSADLFS--AEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLAT  360

Query  350  DKVHD-YPELIAWLENDKTEKIVYDAKKSYIVAHRLDIAIKHIVFDVMLASYIIDPSRTI  408
            D   + +   IA           YD K+S ++  +L+I +    +D  LA+Y++      
Sbjct  361  DSFKQVFQKPIA----------TYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-  409

Query  409  DDVNSVVSYFDQHYVKESIEVFGKGKKRHVPEDEILDHHVGTIIEAINKTKPKMEAQLEE  468
            ++++++   F +  + E   V+GKG KR VP+ ++L +H++  +  +  +K++M  +L  
Sbjct  410  NELSTIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTA  469

Query  469  YNQTNLLDDLELPLARILSEMEETGIYTVATDLQEMEKEIQAKLDVLINNIYNAAGESFN  528
             +Q +L +++ELPLA +L+ ME  GI    + LQ+M  + +  ++ L ++IY+ AG+ FN
Sbjct  470  HEQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFN  529

Query  529  INSPKQLGVVLFETLELP--VIKKTKTGYSTAVDVLEQLQGQHPIIDYILEYRTLSKLQS  586
            INSPKQLG +LFE ++LP  + KKTKTGYSTAVDVLE+L    PI+  IL+YR ++KLQS
Sbjct  530  INSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQS  589

Query  587  TYVEGLQKVISEDNRIHTRFNQTLAQTGRLSSVDPNLQNIPIRLEEGRRIRKAFKSSDDN  646
            TYV GLQ  I  D +IHTR+ Q L+QTGRLSSVDPNLQNIPIRLE+GR IRKAF +S+++
Sbjct  590  TYVIGLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHED  649

Query  647  NVIFSADYSQIELRVLAHITQDESMKQAFINDEDIHTATAMKVFNVQ-PDEVDSLMRRQA  705
             V++S+DYSQIELRVLAHI+ DE +  AF ++ DIHT+TAM+VF ++ + +V +  RR+A
Sbjct  650  AVLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNA  709

Query  706  KAVNFGIVYGISDYGLSQSLGITRKQAKQFIDDYLDSFPGVKQYMEDIVKDCKAQGYVET  765
            KAVNFGIVYGISD+GLS++LGITRKQ+K +ID Y++ +PG+K YME++V++ K +GYVET
Sbjct  710  KAVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVET  769

Query  766  LLHRRRYIPDITSRNFNLRGFAERTAMNTPIQGSAADIIKLAMVNFVNEVKHTDFHAQLL  825
            L+ RRR +PDI SRNFN+R+FAERTA+N+PIQGSAADI+K+AM+N+ + ++  +F+A++L
Sbjct  770  LFKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKML  829

Query  826  LQVHDELIFELPKDEVEAFSEFIEEIMDNALALDVPLKVETSHGKTWYDAK  876
            LQVHDE+++E+P+DE+ A+  ++ + M+ A+ L VPL V+ S G++WY+AK
Sbjct  830  LQVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

338) MI1_03255 in NC_016805


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  681 bits (2575),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 458/897 (52%), Positives = 642/897 (72%), Gaps = 24/897 (2%)

Query  2    TNKKLLLIDGNSLAFRAFYAMYNQLDRMISHEGLHTNALVAFNNFLDKIVDPMAPDLALV  61
             ++KLLLIDG+S+AFRAF+A+YNQ+DR  +H GLHTNA+ +F+  LD ++  + P   LV
Sbjct  3    NKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLV  62

Query  62   AWDAGSGKETHRGELFPEYKDGRSKVPEEFKEQFPYLREMVMLHGLRNYEQAGLEADDII  121
            A DAG  K T R E++++YK GR+K P+EF+EQF+Y+REM+   G+  YE    EADDII
Sbjct  63   AFDAG--KTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120

Query  122  GTYSRMGE--AAGYSVIIVTGDQDLTQLAtenvtvnvtkkgvtDIESYTPAYIKEKFGIT  179
            GT  +M+E     + V IV+GD+DL QL+ EN  V+++KKGV+++E +TPAY+ EK G+T
Sbjct  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180

Query  180  PAQIIDKKALTGDTSDNYPGVTKVGEKTALKLLAEynnidnlydnidKLKQSKMKDNLIN  239
            P Q+ID KAL GD SDN PGVTK+GEKT+LKLL E+ +++ +Y++ID +K SKMK+NLIN
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  240  DRELAFQARELATILTDANLPLPLEEMEYRGVDFEKIIPFYENLDFKQHLAKIKALRKSG  299
            DR+ AF ++ LATI T + + + L+++ Y G D   +  FY+++DF Q       L+K+ 
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQ-------LKKGL  293

Query  300  QLENTKEFDNGINFVELKENNLRAIAMLGDKISVHIEFVGDNYHEGEMIGFAIGNPEVGY  359
              +  +E    I++ E+ +    +  +++      +E + DNYH   +IGFA G+ E   
Sbjct  294  ASQMPQEPVAVISYQEVTNV---SADLFSAEDIFYFETLRDNYHREAIIGFAWGHGE-QI  349

Query  360  YASRDISLLQTEELKSVIENEQILKNVFNVKAQLVLFKRLGLALKGVNFDFILVAYLLDT  419
            YAS D+SLL T+ +K V+++       ++ K   VL+ +LG+ L + ++D  L  YLL T
Sbjct  350  YASTDLSLLATDSFKQVFQKP---IATYDFKRSKVLLSHLGIELVAPSYDARLANYLLST  406

Query  420  VANDNVLSTLAQRF-DVYLAPDEDIYGKGAKFTVPTDTNLLLSHIAHKADGLFKLEKPAF  478
            V +++ LST+A+ F D+ L  D+ +YGKGAK +VP D ++LL H+A+K   L+      +
Sbjct  407  VEDNE-LSTIARIFTDISLEEDDTVYGKGAKRAVP-DKDVLLEHLARKVKVLLDSKSQML  464

Query  479  TELKQHEQTHLYTDIELPLAFVLADMEYQGIKVNPEYLRNKGKDLSERIADIQSAIYIEA  538
              L  HEQ +LY +IELPLA VLA ME +GIKVN   L++ + +    I  +   IY  A
Sbjct  465  DKLTAHEQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMA  524

Query  539  GEEFNLNSPKQLGVLLFEKMGLP--VIKKTKTGYSTAVDVLEKLAPQAPIVDHILQYRQL  596
            G+EFN+NSPKQLG +LFEKM LP  + KKTKTGYSTAVDVLE+LAP APIV  IL+YRQ+
Sbjct  525  GQEFNINSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQI  584

Query  597  AKLKSTYIDGLLSVIYPKDSKIHTRFLQTLTQTGRLSSVDPNLQNIPMRSEEGRLIRTAF  656
            +KL+STY+ GL   I + D+KIHTR++Q LTQTGRLSSVDPNLQNIP+R E+GRLIR AF
Sbjct  585  TKLQSTYVIGLQDYILA-DGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAF  643

Query  657  VPSHPNWQIFGADYSQIELRVLAHVTGDKNMQKAFLNGEDIHAETARAVFGLADDAVVDP  716
             PSH +  ++++DYSQIELRVLAH++GD ++  AF +G DIH+ TA  VFG+   A V +
Sbjct  644  TPSHEDAVLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTA  703

Query  717  LKRRTAKAVNFGIVYGISDYGLANNLGISRAEAKRFIDTYFQEFPQIHEWMNTIKTFAHE  776
              RR AKAVNFGIVYGISD+GL+NNLGI+R ++K +IDTYF+ +P I   M+ +   A +
Sbjct  704  NDRRNAKAVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKD  763

Query  777  HGYVETIAHRRRYLPDIQAKNFNLRSFAERTAMNSPIQGSAADIIKIAMIKVNEALRKNN  836
             GYVET+  RRR LPDI+++NFN+RSFAERTA+NSPIQGSAADI+KIAMI+++ AL+   
Sbjct  764  KGYVETLFKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGG  823

Query  837  LQARMLLQVHDELIFETPVDEIDELTEVVTNVMDSAVALDVPLKVDAHHGDTWYDAK  893
            ++A+MLLQVHDE+++E P DE+  +  +V + M++AV L VPL VD   G++WY+AK
Sbjct  824  FRAKMLLQVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

339) LEUM_0713 in NC_008531


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  681 bits (2574),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 457/897 (51%), Positives = 641/897 (72%), Gaps = 24/897 (2%)

Query  2    TNKKLLLVDGNSLAFRAFYAMYNQLDRMISHEGLHTNALVAFNNFLDKIVDPMAPDLALV  61
             ++KLLL+DG+S+AFRAF+A+YNQ+DR  +H GLHTNA+ +F+  LD ++  + P   LV
Sbjct  3    NKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLV  62

Query  62   AWDAGSGKETHRGKLFPEYKDGRSKVPEEFKEQFPYLREMVMLHGLRNYEQAGLEADDII  121
            A DAG  K T R  ++++YK GR+K P+EF+EQF+Y+REM+   G+  YE    EADDII
Sbjct  63   AFDAG--KTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120

Query  122  GTYSRMGE--AAGYSVIIVTGDQDLTQLAtenvtvnvtkkgvtDIESYTPAYIKEKFGLT  179
            GT  +M+E     + V IV+GD+DL QL+ EN  V+++KKGV+++E +TPAY+ EK GLT
Sbjct  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180

Query  180  PAQIIDKKALTGDTSDNYPGVTKVGEKTALKLLAEynnidnlydnidKLKQSKMKDNLIN  239
            P Q+ID KAL GD SDN PGVTK+GEKT+LKLL E+ +++ +Y++ID +K SKMK+NLIN
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  240  DRELAFQARELATILTDANLPLPLEEMEYRGVDFEKIIPFYENLDFKQHLAKIKALRKSG  299
            DR+ AF ++ LATI T + + + L+++ Y G D   +  FY+++DF Q       L+K+ 
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQ-------LKKGL  293

Query  300  QLENTKEFDNGINFVELKENNLRAIAMLGDKISVHIEFVGDNYHEGEMIGFAIGNPEVGY  359
              +  +E    I++ E+ +    +  +++      +E + DNYH   +IGFA G+ E   
Sbjct  294  ASQMPQEPVAVISYQEVTNV---SADLFSAEDIFYFETLRDNYHREAIIGFAWGHGE-QI  349

Query  360  YASRDISLLQTEELKSVIENEQILKNVFNVKAQLVLFKRLGLALKGVNFDFILVAYLLDT  419
            YAS D+SLL T+ +K V+++       ++ K   VL+ +LG+ L + ++D  L  YLL T
Sbjct  350  YASTDLSLLATDSFKQVFQKP---IATYDFKRSKVLLSHLGIELVAPSYDARLANYLLST  406

Query  420  VANDNVLSTLAQRF-DVYLAPDEDIYGKGAKFTVPTDTNLLLSHVAHKADGLFKLEKPAF  478
            V +++ LST+A+ F D+ L  D+ +YGKGAK +VP D ++LL H+A+K   L+      +
Sbjct  407  VEDNE-LSTIARIFTDISLEEDDTVYGKGAKRAVP-DKDVLLEHLARKVKVLLDSKSQML  464

Query  479  TELKQHEQTHLYTDIELPLAFVLADMEYQGIKVNPEYLRNKGKDLSERIADIQSAIYIEA  538
              L  HEQ +LY +IELPLA VLA ME +GIKVN   L++ + +    I  +   IY  A
Sbjct  465  DKLTAHEQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMA  524

Query  539  GEEFNLNSPKQLGVLLFEKMGLP--VIKKTKTGYSTAVDVLEKLAPQAPIVDHILQYRQL  596
            G+EFN+NSPKQLG +LFEKM LP  + KKTKTGYSTAVDVLE+LAP APIV  IL+YRQ+
Sbjct  525  GQEFNINSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQI  584

Query  597  AKLKSTYIDGLLSVIYPKDSKIHTRFLQTLTQTGRLSSVDPNLQNIPMRSEEGRLIRTAF  656
            +KL+STY+ GL   I + D+KIHTR++Q LTQTGRLSSVDPNLQNIP+R E+GRLIR AF
Sbjct  585  TKLQSTYVIGLQDYILA-DGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAF  643

Query  657  VPSHPNWQIFGADYSQIELRVLAHVTGDKNMQKAFLNGEDIHAETARAVFGLADDAVVDP  716
             PSH +  ++++DYSQIELRVLAH++GD ++  AF +G DIH+ TA  VFG+   A V +
Sbjct  644  TPSHEDAVLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTA  703

Query  717  LKRRTAKAVNFGIVYGISDYGLANNLGISRAEAKRFIDTYFQEFPQIHEWMNTIKTFAHE  776
              RR AKAVNFGIVYGISD+GL+NNLGI+R ++K +IDTYF+ +P I   M+ +   A +
Sbjct  704  NDRRNAKAVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKD  763

Query  777  HGYVETIAHRRRYLPDIQAKNFNLRSFAERTAMNSPIQGSAADIIKIAMIKVNEALRENN  836
             GYVET+  RRR LPDI+++NFN+RSFAERTA+NSPIQGSAADI+KIAMI+++ AL+   
Sbjct  764  KGYVETLFKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGG  823

Query  837  LQARMLLQVHDELIFETPVDEIDELTEVVTNVMDSAVALDVPLKVDAHHGDTWYDAK  893
            ++A+MLLQVHDE+++E P DE+  +  +V + M++AV L VPL VD   G++WY+AK
Sbjct  824  FRAKMLLQVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

340) SE1367 in NC_004461


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  681 bits (2574),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 422/892 (48%), Positives = 632/892 (71%), Gaps = 33/892 (3%)

Query  29   NKLVLIDGNSLSFRAFYAL----PLLSNHAGIHTNAVYGFAMLLEKIIKEEKPNHFLVAF  84
            NKL+LIDG+S++FRAF+AL      + NH+G+HTNA+YGF ++L+ ++K  +P H LVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  85   DAGKTTFRHSKYSEYKGGRQKTPPELSEQFPYIRQLLDAYHIKRYELDNYEADDIIGTLS  144
            DAGKTTFR   Y++YK+GR KTP E+ EQF+YIR++L A  I  YEL++YEADDIIGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  145  RQADEED--FETIIITGDRDLTQLATDNVTIYYTKKGVTDVDHYTPKFIAEKYNGLVPKQ  202
            + A+  +  F+  I++GD+DL QL+ +N  +  +KKGV++ +++TP ++ EK  GL P+Q
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEK-MGLTPNQ  183

Query  203  IIDMKGLMGDTSDNIPGVAGVGEKTAIKLLNQFESVEGVYEHIEEVTAKKLKEKLINSKD  262
            +ID+K+LMGD SDNIPGV+ +GEKT++KLL++F S+EG+YEHI+   + K+KE+LIN +D
Sbjct  184  FIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRD  243

Query  263  DALMSKDLATINVHSPIEVSledtkltlqddttkkielfkklefkqllADIDTSSTNEEV  322
            +A++SK LATIN  SPI ++L+D      D ++           +   + + +   +E V
Sbjct  244  QAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKG-LASQMPQEPV  302

Query  323  IDKTFEIEQDFQNVDLNDL--NEAVIHFELEGTNYLKDTILKFG------FYTNHQHVVI  374
               ++   Q+  NV   DL   E ++ FE    NY +++I+ F+      +Y++ +  ++
Sbjct  303  AVISY---QEVTNVS-ADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLL  358

Query  375  NAEDVKDYKHLVQWLEDKNTTKIVYDAKKTYVSAHRLGINIENIEFDVMLASYIIDPSRS  434
             ++    +K++ Q           YD K++ V   +LGI++    +D  LA+Y++     
Sbjct  359  ATDS---FKQVFQ------KPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED  409

Query  435  IDDVKSVVSLYGQNYVKDNITIFGKGKKHHIPEEPILNEHIASVTEAIAAVTPTMKSQLE  494
             +++ ++  ++ +  + ++ T++GKG K+ +P+  +L EH+A     +    + M  +L 
Sbjct  410  -NELSTIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLT  468

Query  495  DYNQIELLKDLELPLARILSEMEEIGIYTDINDLKEMEFEIQKKLDVLISNIHESAGEAF  554
              +Q++L +++ELPLA +L+ ME  GI  +   L++M  + +  ++ L  +I + AG+ F
Sbjct  469  AHEQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEF  528

Query  555  NINSPKQLGVVLFETLQLP--VIKKTKTGYSTAVDVLEKLQGEHPIIDDILEYRQLAKLQ  612
            NINSPKQLG +LFE +QLP  + KKTKTGYSTAVDVLE+L    PI+  IL+YRQ++KLQ
Sbjct  529  NINSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQ  588

Query  613  STYVEGLQKVISKDHRIHTRFNQTLAQTGRLSSIDPNLQNIPIRLEEGRKIRKAFKPTSK  672
            STYV GLQ  I  D +IHTR+ Q L+QTGRLSS+DPNLQNIPIRLE+GR IRKAF P+  
Sbjct  589  STYVIGLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHE  648

Query  673  DSVILSADYSQIELRVLAHITQDESLKHAFINGHDIHTATAMKVFNVE-SDQVDSLMRRQ  731
            D+V+LS+DYSQIELRVLAHI+ DE L  AF +G DIHT+TAM+VF ++ + +V +  RR+
Sbjct  649  DAVLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRN  708

Query  732  AKAVNFGIVYGISDYGLSQSLGITRKQAKAFIDDYLASFPGVKQYMSDIVKDAKAQGYVE  791
            AKAVNFGIVYGISD+GLS++LGITRKQ+K++ID Y+  +PG+K YM ++V++AK +GYVE
Sbjct  709  AKAVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVE  768

Query  792  TLLHRRRYIPDITSRNFNLRSFAERTAMNTPIQGSAADIIKLAMVKFSEKIKETKYHAKL  851
            TL+ RRR +PDI SRNFN+RSFAERTA+N+PIQGSAADI+K+AM+++   ++   ++AK+
Sbjct  769  TLFKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKM  828

Query  852  LLQVHDELIFEIPKSEVEDFSKFVEEIMEQALVLDVPLKVDSNYGATWYDAK  903
            LLQVHDE+++E+P+ E+  + K+V + ME A+ L VPL VD + G +WY+AK
Sbjct  829  LLQVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

341) polA in NC_011999


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  680 bits (2570),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 439/886 (50%), Positives = 652/886 (74%), Gaps = 23/886 (2%)

Query  3    DKLILIDGNSIAFRAFYAL----PLLKNQSNLHTNAIYGFTLILDKLIKEEQPTHFLIAF  58
            +KL+LIDG+S+AFRAF+AL      +KN+S LHTNAIYGF L+LD ++K  +PTH L+AF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  59   DAGKTTFRHEMYKDYKGGRQKTPSELSEQFPYIRKLAEAYQIKHYEQDMYEADDIIGTLA  118
            DAGKTTFR EMY DYK+GR KTP E+ EQF+YIR +  A  I  YE + YEADDIIGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  119  KQA--TENKLETIIVTGDRDLTQLASDYVTIYYTKKGVTDIDKYTPQFIQEQYGFEPEKI  176
            K A  TE  ++  IV+GD+DL QL+ +   +  +KKGV++++ +TP ++ E+ G+ P+++
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  177  IDLKGLMGDKSDNIPGVPGVGEKTALKLLHEYGTVEAVLDNLEHIKGKKLNENLTNHKDD  236
            IDLK+LMGDKSDNIPGV  +GEKT+LKLLHE+G++E++ ++++ +K  K++ENL N++D+
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRDQ  244

Query  237  ALMSKQLAKINTDAPIAVNLNDTLLPEKDESKKIALFQELDF---KQKLDNIDAETQVTE  293
            A++SK LA INT +PI++ L+D +    D +    +++E+DF   K+ L +  ++  V+ 
Sbjct  245  AFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEPVAV  304

Query  294  KKTIEISNQFHTFDFSTIESMAIRIRCFQDNYLKNEIIGVGILVGAHTFVIPPDEIAQNE  353
                E++N    + FS+ +   + +  ++DNY ++ IIG +   G + +      +   +
Sbjct  305  ISYQEVTNVSADL-FSAED--IFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLATD  361

Query  354  SFINALQNEDTKKYVYDAKETKVLFSRLDIDIKGIEHCVMLASYLLDPALKIIDVAQSAQ  413
            SF + +Q+  +    YD K +KVL+S+L+I++ +      LA+YLL      ++  + + 
Sbjct  362  SFKQVFQKPIA---TYDFKRSKVLLSHLGIELVAPSYDARLANYLLST----VEDNELST  414

Query  414  MQGIY---YVESDEMIFGKGAKMHIPERTNLFKHIASEVNAIHEVSALQIRKlnelkqle  470
            +  I+    +E D+ ++GKGAK  +P++  L+ H+A  V+ + +  +  + KL    QL+
Sbjct  415  IARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLD  474

Query  471  lltalelplslvlADMEMQGIKVNRQTLQEMQQEIQSRLDELITRIHEHAGSTFNINSPK  530
            L   +ELPL+ VLA ME++GIKVNR TLQ+M ++ +  ++ L   I + AG  FNINSPK
Sbjct  475  LYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPK  534

Query  531  QLGVVLFEDLKLDSPkkkktktGYSTAVDVLESLAGKHPIIEDILLYRTLSKLQSTYVEG  590
            QLG +LFE ++L     KKTKTGYSTAVDVLE LA   PI+  IL YR ++KLQSTYV G
Sbjct  535  QLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIG  594

Query  591  LQKLIGDDDKIHTRFNQVIAQTGRLSSIDPNLQNIPVRLDEGRKIRKAFVPSEPNSVIFA  650
            LQ  I  D+KIHTR+ Q ++QTGRLSS+DPNLQNIP+RL++GR IRKAF PS+ ++V+++
Sbjct  595  LQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLS  654

Query  651  ADYSQIELRVLAHITGDKGMLEAFNQGIDIHTKTAMKVFNVER-EEVTSDMRRQAKAVNF  709
            +DYSQIELRVLAHI+GD  ++ AFN+G DIHT TAM+VF +++  +VT++ RR+AKAVNF
Sbjct  655  SDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNF  714

Query  710  GIVYGISDYGLSQSLGITRKDAQAFIDNYLESFPDVKAYMHDIIQEAKQQGYVTTLLNRR  769
            GIVYGISD+GLS++LGITRK+++++ID Y+E +P++KAYM+++++EAK++GYV TL++RR
Sbjct  715  GIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRR  774

Query  770  RYIPDITSRNFNLRGFAERTAMNTPIQGSAADIIKLAMVHYNEQVKETDFKAKLLLQVHD  829
            R +PDI SRNFN+R+FAERTA+N+PIQGSAADI+K+AM++ +  ++  +F+AK+LLQVHD
Sbjct  775  RELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHD  834

Query  830  ELIFEVPKDELEAFSLFVKHVMENALELKVPLEVEYDSGESWYEAK  875
            E+++EVP+DEL A+  +VK+ ME A++L VPL V+  +G+SWYEAK
Sbjct  835  EIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

342) EAT1b_0662 in NC_012673


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  678 bits (2564),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 441/882 (50%), Positives = 642/882 (73%), Gaps = 25/882 (2%)

Query  2    NKLLVLDGNSLTYRAFFAL----PPMSDASGRNTNAVYGFTMMLLKLMEDEQPTHFAVAF  57
            NKLL++DG+S+++RAFFAL        + SG +TNA+YGF +ML  +M   +PTH  VAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  58   DASKKTFRHDTFAEYKGGRQKTPGELREQFPLVRDVCRAFGISVLELDQYEADDIIGTLS  117
            DA+K TFR + +A+YK+GR KTP+E+REQF+ +R++  A+GI+  EL++YEADDIIGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  118  K-----DPTFDQVTVVTGDKDLLQLINERVTVYLTKRGITEVEKMTETAFKERYDGLQPI  172
            K     +  FD VT+V+GDKDL+QL +E   V ++K+G++E E  T + + E+  GL P 
Sbjct  125  KMAERTEVPFD-VTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEK-MGLTPN  182

Query  173  QMIDLKGLMGDKSDNIPGIPGVGEKTALKLIATYGTVEALYEHTDELK-GKQKEKVVANE  231
            Q IDLK+LMGDKSDNIPG+  +GEKT+LKL+  +G++E++YEH D +K +K KE+++ + 
Sbjct  183  QFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDR  242

Query  232  QEAKMSKQLATIYTDVPIDVTMDELVFKPYDASVVKTLFMDLQFKSLIGKLADTSSEEPV  291
            ++A +SK LATI T  PI + +D++V++  D + +  ++ +++F  L   LA   ++EPV
Sbjct  243  DQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEPV  302

Query  292  EKAERPTIALVDQDL--SRAVLMLEQLHDDYFEEDVIGVA-IASERGVTIGDVTLLEDER  348
                   ++ V  DL  +  ++ +E L+D+Y  E +IG A   +E+  +  D++LL  + 
Sbjct  303  AVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLATDS  362

Query  349  VKEWIEDETKTTICLDAKQTIIQLKRHQLAL--RGYEDLLVAgyllnlsggtslssIAAH  406
             K+ ++   K     D K++ + L +  + L   +Y+  L A YLL+   +  LS+IA  
Sbjct  363  FKQVFQ---KPIATYDFKRSKVLLSHLGIELVAPSYDARL-ANYLLSTVEDNELSTIARI  418

Query  407  FT-YPLEEDETVYGKGAKIKVPEENVFHAHLAEKAYAIYTLFERVVSELKENEQTELYEA  465
            FT  +LEED+TVYGKGAK  VP+ +V+  HLA K   +     +++  L  +EQ +LY+ 
Sbjct  419  FTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQN  478

Query  466  LEKPLVSVLAEMEWAGIHVNVETLQHMETDLRERLNALEITIHELAGEPFNINSPKQLGV  525
            +E PL +VLA ME  GI VN  TLQ+M  + +  ++AL   I ++AG+ FNINSPKQLG 
Sbjct  479  IELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGS  538

Query  526  VLFEKLSLP--PVKKTKTGYSTAADVLEKLAPLHPIIEKIMHYRELGKLQSTYVEGLQKV  583
            +LFEK+ LP    KKTKTGYSTA DVLE+LAP+ PI+ KI++YR++ KLQSTYV GLQ  
Sbjct  539  ILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDY  598

Query  584  VKDDGKIHTRYTQTLTQTGRLSSVNPNLQNIPIRLEEGRRIRKAFTASEPGWVLYAVDYS  643
            +  DGKIHTRY Q LTQTGRLSSV+PNLQNIPIRLE+GR IRKAFT+S+ + VL + DYS
Sbjct  599  ILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYS  658

Query  644  QIELRIMAHMSQDEKMMAAFLHDEDIHTSTAANVFKVS-AEEVTSLMRRQAKAVNFGIIY  702
            QIELR++AH+S DE ++AAF ++ DIHTSTA  VF +  A +VT+  RR+AKAVNFGI+Y
Sbjct  659  QIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVY  718

Query  703  GISDYGLSQNLGITRKEAQTFIDTYFEQFPGVKTFMDAAIERAREHGFVETMLKRRRNIP  762
            GISD+GLS+NLGITRK+++++IDTYFE++PG+K++M+  +  A++ G+VET++KRRR++P
Sbjct  719  GISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELP  778

Query  763  DIHSRNFNLRGFAERTAINTPIQGTAADIIKKAMIDVDHALNASKLQSKLLLQVHDELIF  822
            DI+SRNFN+R+FAERTAIN+PIQG+AADI+K AMI++D AL+A+ +++K+LLQVHDE+++
Sbjct  779  DINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVL  838

Query  823  EGPTEEMEALEKLVTEAMEQTVTLDVPLRADGAVGTTWFDTK  864
            E P +E+ A+ KLV ++ME +V L VPL  D + G +W+++K
Sbjct  839  EVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

343) polA in NC_017763


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  678 bits (2562),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 428/891 (49%), Positives = 643/891 (73%), Gaps = 31/891 (3%)

Query  2    NKLVLIDGNSLSFRAFYAL----PLLSNKAGIHTNAVYGFAMLLEKILKEEKPNHFLVAF  57
            NKL+LIDG+S++FRAF+AL      + N +G+HTNA+YGF ++L+ ++K  +P H LVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  58   DAGKTTFRHEKYSEYKGGRQKTPPELSEQFPYIRQLLDAYHIKRYELDNYEADDIIGTLS  117
            DAGKTTFR E Y++YK+GR KTP E+ EQF+YIR++L A  I  YEL++YEADDIIGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  118  KEADKAG--FQTIIITGDRDLTQLATDNVTIYYTKKGVTDVDHYTPDFIAEKYNGLTPNQ  175
            K A+++   F+  I++GD+DL QL+ +N  +  +KKGV++ +++TP ++ EK  GLTPNQ
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEK-MGLTPNQ  183

Query  176  IIDMKGLMGDTSDNIPGVAGVGEKTAIKLLNQFDTVEGVYEHLDEISGKKLKEKLQNSKE  235
            +ID+K+LMGD SDNIPGV+ +GEKT++KLL++F+++EG+YEH+D +   K+KE+L N ++
Sbjct  184  FIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRD  243

Query  236  DALMSKELATINVDSPIEVKLEDTLMTHQDeqqeki---elfkklefkqllADIDQSASV  292
            +A++SK LATIN  SPI + L+D +    D         E+      K L +++ Q +  
Sbjct  244  QAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEPVA  303

Query  293  EDAIEKTIEIETSFDNVDFTSLKEAAIHFELDGGNYLRNNILKFSLFTGEKHIVINAD--  350
              + +   ++ + +    F++  E  + FE   +NY R+ I+ F+   GE +I  ++D  
Sbjct  304  VISYQEVTNVSADL----FSA--EDIFYFETLRDNYHREAIIGFAWGHGE-QIYASTDLS  356

Query  351  --DINNYAELVSWLENPNTKKVVYDAKKTYVASHRLGIDIQNISFDIMLASYIIDPSRTI  408
                +++ ++   +++P +    YD K++ V   +LGI++   S+D  LA+Y++      
Sbjct  357  LLATDSFKQV---FQKPIA---TYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-  409

Query  409  SDVQSVVSLYGQSFVKDDVSIYGKGKKFKVPEDDVLNPYVASITDAIYFAKPNMDKQLEE  468
            +++ ++  ++ +  + +D ++YGKG K  VP+ DVL   +A     +  +K++M  +L  
Sbjct  410  NELSTIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTA  469

Query  469  YNQVELLADLELPLAKILSEMEEIGIFTDVHDLEEMEKEIQEKLDVLIRNIHDAAGEDFN  528
             +Q++L  ++ELPLA++L+ ME  GI  +   L++M  + +  ++ L ++I D AG++FN
Sbjct  470  HEQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFN  529

Query  529  INSPKQLGVVLFETLQLP--VIKKTKTGYSTAVDVLEQLQGEHPIIDYILEYRQLSKLQS  586
            INSPKQLG +LFE +QLP  + KKTKTGYSTAVDVLE+L    PI+  IL+YRQ++KLQS
Sbjct  530  INSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQS  589

Query  587  TYVEGLQKVISDDQRIHTRFNQTLAQTGRLSSVDPNLQNIPVRLEEGRKIRKAFKPTSKD  646
            TYV GLQ  I  D +IHTR+ Q L+QTGRLSSVDPNLQNIP+RLE+GR IRKAF P+  D
Sbjct  590  TYVIGLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHED  649

Query  647  SVILSADYSQIELRVLAHITQDESMKEAFINGDDIHTATAMKVFGVE-ADQVDSLMRRQA  705
            +V+LS+DYSQIELRVLAHI+ DE +  AF +G DIHT+TAM+VFG++ A +V +  RR+A
Sbjct  650  AVLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNA  709

Query  706  KAVNFGIVYGISDYGLSQSLGITRKKAKAFIDDYLASFPGVKQYMSDIVKDAKALGYVET  765
            KAVNFGIVYGISD+GLS++LGITRK++K++ID Y+  +PG+K YM ++V++AK  GYVET
Sbjct  710  KAVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVET  769

Query  766  LLHRRRYIPDITSRNFNLRGFAERTAMNTPIQGSAADIIKLAMVKFAQKMKETTYQAKLL  825
            L+ RRR +PDI SRNFN+R+FAERTA+N+PIQGSAADI+K+AM+++ + ++   ++AK+L
Sbjct  770  LFKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKML  829

Query  826  LQVHDELIFEVPKsevdsfsefveeIMENALQLDVPLKVDSSYGATWYDAK  876
            LQVHDE+++EVP+ E+ ++  +V + ME A++L VPL VD S G +WY+AK
Sbjct  830  LQVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

344) polA in NC_007622


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  678 bits (2564),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 427/888 (49%), Positives = 637/888 (72%), Gaps = 25/888 (2%)

Query  2    NKLVLIDGNSLSFRAFYAL----PLLSNKAGIHTNAVYGFAMLLEKILKEEKPNHFLVAF  57
            NKL+LIDG+S++FRAF+AL      + N +G+HTNA+YGF ++L+ ++K  +P H LVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  58   DAGKTTFRHEKYSEYKGGRQKTPPELSEQFPYIRQLLDAYHIKRYELDNYEADDIIGTLS  117
            DAGKTTFR E Y++YK+GR KTP E+ EQF+YIR++L A  I  YEL++YEADDIIGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  118  KEADKAG--FQTIIITGDRDLTQLATDNVTIYYTKKGVTDVDHYTPDFIAEKYNGLTPNQ  175
            K A+++   F+  I++GD+DL QL+ +N  +  +KKGV++ +++TP ++ EK  GLTPNQ
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEK-MGLTPNQ  183

Query  176  IIDMKGLMGDTSDNIPGVAGVGEKTAIKLLNQFGTVEGVYEHLDEISGKKLKEKLQNSKE  235
            +ID+K+LMGD SDNIPGV+ +GEKT++KLL++FG++EG+YEH+D +   K+KE+L N ++
Sbjct  184  FIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRD  243

Query  236  DALMSKELATINVDSPIEVKLEDTLMTHQDeqqekielfkklefkqllADIDQSASIEDA  295
            +A++SK LATIN  SPI + L+D +    D              +   + +    + E  
Sbjct  244  QAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKG-LASQMPQEPV  302

Query  296  IEKTFEIETSFDNVDFTSLKEAAIHFELHGGNYLRNNILKFSLFTGEKHIVINAD----D  351
               +++  T+     F++  E  + FE   +NY R+ I+ F+   GE +I  ++D     
Sbjct  303  AVISYQEVTNVSADLFSA--EDIFYFETLRDNYHREAIIGFAWGHGE-QIYASTDLSLLA  359

Query  352  INNYAELVSWLENPNTKKVVYDAKKTYVASHRLGIDIQNISFDIMLASYIIDPSRTISDV  411
             +++ ++   +++P +    YD K++ V   +LGI++   S+D  LA+Y++      +++
Sbjct  360  TDSFKQV---FQKPIA---TYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NEL  412

Query  412  QSVVSLYGQSFVKDDVSIYGKGKKFKVPEDDVLNPYVASITDAIYFAKPNMDKQLEEYNQ  471
             ++  ++ +  + +D ++YGKG K  VP+ DVL   +A     +  +K++M  +L   +Q
Sbjct  413  STIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQ  472

Query  472  VELLADLELPLAKILSEMEEIGIYTDVHDLEEMEKEIQEKLDVLIRNIHDAAGEDFNINS  531
            ++L  ++ELPLA++L+ ME  GI  +   L++M  + +  ++ L ++I D AG++FNINS
Sbjct  473  LDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINS  532

Query  532  PKQLGVVLFETLQLP--VIKKTKTGYSTAVDVLEQLQGEHPIIDYILEYRQLSKLQSTYV  589
            PKQLG +LFE +QLP  + KKTKTGYSTAVDVLE+L    PI+  IL+YRQ++KLQSTYV
Sbjct  533  PKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYV  592

Query  590  EGLQKVISDDQRIHTRFNQTLAQTGRLSSVDPNLQNIPVRLEEGRKIRKAFKPTSKDSVI  649
             GLQ  I  D +IHTR+ Q L+QTGRLSSVDPNLQNIP+RLE+GR IRKAF P+  D+V+
Sbjct  593  IGLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVL  652

Query  650  LSADYSQIELRVLAHITQDESMKEAFINGDDIHTATAMKVFGVE-ADQVDILMRRQAKAV  708
            LS+DYSQIELRVLAHI+ DE +  AF +G DIHT+TAM+VFG++ A +V    RR+AKAV
Sbjct  653  LSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAV  712

Query  709  NFGIVYGISDYGLSQSLGITRKKAKAFIDDYLASFPGVKQYMSDIVKDAKALGYVETLLH  768
            NFGIVYGISD+GLS++LGITRK++K++ID Y+  +PG+K YM ++V++AK  GYVETL+ 
Sbjct  713  NFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFK  772

Query  769  RRRYIPDITSRNFNLRGFAERTAMNTPIQGSAADIIKLAMVKFAQKMKETTYQAKLLLQV  828
            RRR +PDI SRNFN+R+FAERTA+N+PIQGSAADI+K+AM+++ + ++   ++AK+LLQV
Sbjct  773  RRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQV  832

Query  829  HDELIFEVPKsevdsfsefveeIMENALQLDVPLKVDSSYGATWYDAK  876
            HDE+++EVP+ E+ ++  +V + ME A++L VPL VD S G +WY+AK
Sbjct  833  HDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

345) SAOV_1678 in NC_017337


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  678 bits (2563),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 426/888 (48%), Positives = 639/888 (72%), Gaps = 25/888 (2%)

Query  2    NKLVLIDGNSLSFRAFYAL----PLLSNKAGIHTNAVYGFAMLLEKILKEEKPNHFLVAF  57
            NKL+LIDG+S++FRAF+AL      + N +G+HTNA+YGF ++L+ ++K  +P H LVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  58   DAGKTTFRHEKYSEYKGGRQKTPPELSEQFPYIRQLLDAYHIKRYELDNYEADDIIGTLS  117
            DAGKTTFR E Y++YK+GR KTP E+ EQF+YIR++L A  I  YEL++YEADDIIGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  118  KEADKAG--FQTIIITGDRDLTQLATDNVTIYYTKKGVTDVDHYTPDFIAEKYNGLTPNQ  175
            K A+++   F+  I++GD+DL QL+ +N  +  +KKGV++ +++TP ++ EK  GLTPNQ
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEK-MGLTPNQ  183

Query  176  IIDMKGLMGDTSDNIPGVAGVGEKTAIKLLNQFDTVEGVYEHLDEISGKKLKEKLQNSKE  235
            +ID+K+LMGD SDNIPGV+ +GEKT++KLL++F+++EG+YEH+D +   K+KE+L N ++
Sbjct  184  FIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRD  243

Query  236  DALMSKELATINVDSPIEVKLEDTLMTHQDeqqekielfkklefkqllADIDQSASVEDA  295
            +A++SK LATIN  SPI + L+D +    D              +   + +    + E  
Sbjct  244  QAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKG-LASQMPQEPV  302

Query  296  IEKTFEIETSFDNVDFTSLKEAVIHFELDGGNYLRNNILKFSLFTGEKHIVINAD----D  351
               +++  T+     F++  E ++ FE   +NY R+ I+ F+   GE +I  ++D     
Sbjct  303  AVISYQEVTNVSADLFSA--EDIFYFETLRDNYHREAIIGFAWGHGE-QIYASTDLSLLA  359

Query  352  INNYAELVSWLENPNTKKVVYDAKKTYVASHRLGIDIQNISFDIMLASYIIDPSRTISDV  411
             +++ ++   +++P +    YD K++ V   +LGI++   S+D  LA+Y++      +++
Sbjct  360  TDSFKQV---FQKPIA---TYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NEL  412

Query  412  QSVVSLYGQSFVKDDVSIYGKGKKFKVPEDDVLNPYVASITDAIYFAKPNMDKQLEEYNQ  471
             ++  ++ +  + +D ++YGKG K  VP+ DVL   +A     +  +K++M  +L   +Q
Sbjct  413  STIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQ  472

Query  472  VELLADLELPLAKILSEMEEIGIFTDVHDLEEMEKEIQEKLDVLIRNIHDAAGEDFNINS  531
            ++L  ++ELPLA++L+ ME  GI  +   L++M  + +  ++ L ++I D AG++FNINS
Sbjct  473  LDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINS  532

Query  532  PKQLGVVLFETLQLP--VIKKTKTGYSTAVDVLEQLQGEHPIIDYILEYRQLSKLQSTYV  589
            PKQLG +LFE +QLP  + KKTKTGYSTAVDVLE+L    PI+  IL+YRQ++KLQSTYV
Sbjct  533  PKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYV  592

Query  590  EGLQKVISDDQRIHTRFNQTLAQTGRLSSVDPNLQNIPVRLEEGRKIRKAFKPTSKDSVI  649
             GLQ  I  D +IHTR+ Q L+QTGRLSSVDPNLQNIP+RLE+GR IRKAF P+  D+V+
Sbjct  593  IGLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVL  652

Query  650  LSADYSQIELRVLAHITQDESMKEAFINGDDIHTATAMKVFGVE-ADQVDSLMRRQAKAV  708
            LS+DYSQIELRVLAHI+ DE +  AF +G DIHT+TAM+VFG++ A +V +  RR+AKAV
Sbjct  653  LSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAV  712

Query  709  NFGIVYGISDYGLSQSLGITRKKAKAFIDDYLASFPGVKQYMSDIVKDAKALGYVETLLH  768
            NFGIVYGISD+GLS++LGITRK++K++ID Y+  +PG+K YM ++V++AK  GYVETL+ 
Sbjct  713  NFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFK  772

Query  769  RRRYIPDITSRNFNLRGFAERTAMNTPIQGSAADIIKLAMVKFAQKMKETTYQAKLLLQV  828
            RRR +PDI SRNFN+R+FAERTA+N+PIQGSAADI+K+AM+++ + ++   ++AK+LLQV
Sbjct  773  RRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQV  832

Query  829  HDELIFEVPKsevdsfsefveeIMENALQLDVPLKVDSSYGATWYDAK  876
            HDE+++EVP+ E+ ++  +V + ME A++L VPL VD S G +WY+AK
Sbjct  833  HDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

346) polA in NC_017349


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  678 bits (2563),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 426/888 (48%), Positives = 639/888 (72%), Gaps = 25/888 (2%)

Query  2    NKLVLIDGNSLSFRAFYAL----PLLSNKAGIHTNAVYGFAMLLEKILKEEKPNHFLVAF  57
            NKL+LIDG+S++FRAF+AL      + N +G+HTNA+YGF ++L+ ++K  +P H LVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  58   DAGKTTFRHEKYSEYKGGRQKTPPELSEQFPYIRQLLDAYHIKRYELDNYEADDIIGTLS  117
            DAGKTTFR E Y++YK+GR KTP E+ EQF+YIR++L A  I  YEL++YEADDIIGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  118  KEADKAG--FQTIIITGDRDLTQLATDNVTIYYTKKGVTDVDHYTPDFIAEKYNGLTPNQ  175
            K A+++   F+  I++GD+DL QL+ +N  +  +KKGV++ +++TP ++ EK  GLTPNQ
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEK-MGLTPNQ  183

Query  176  IIDMKGLMGDTSDNIPGVAGVGEKTAIKLLNQFDTVEGVYEHLDEISGKKLKEKLQNSKE  235
            +ID+K+LMGD SDNIPGV+ +GEKT++KLL++F+++EG+YEH+D +   K+KE+L N ++
Sbjct  184  FIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRD  243

Query  236  DALMSKELATINVDSPIEVKLEDTLMTHQDeqqekielfkklefkqllADIDQSASVEDA  295
            +A++SK LATIN  SPI + L+D +    D              +   + +    + E  
Sbjct  244  QAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKG-LASQMPQEPV  302

Query  296  IEKTFEIETSFDNVDFTSLKEAVIHFELDGGNYLRNNILKFSLFTGEKHIVINAD----D  351
               +++  T+     F++  E ++ FE   +NY R+ I+ F+   GE +I  ++D     
Sbjct  303  AVISYQEVTNVSADLFSA--EDIFYFETLRDNYHREAIIGFAWGHGE-QIYASTDLSLLA  359

Query  352  INNYAELVSWLENPNTKKVVYDAKKTYVASHRLGIDIQNISFDIMLASYIIDPSRTISDV  411
             +++ ++   +++P +    YD K++ V   +LGI++   S+D  LA+Y++      +++
Sbjct  360  TDSFKQV---FQKPIA---TYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NEL  412

Query  412  QSVVSLYGQSFVKDDVSIYGKGKKFKVPEDDVLNPYVASITDAIYFAKPNMDKQLEEYNQ  471
             ++  ++ +  + +D ++YGKG K  VP+ DVL   +A     +  +K++M  +L   +Q
Sbjct  413  STIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQ  472

Query  472  VELLADLELPLAKILSEMEEIGIFTDVHDLEEMEKEIQEKLDVLIRNIHDAAGEDFNINS  531
            ++L  ++ELPLA++L+ ME  GI  +   L++M  + +  ++ L ++I D AG++FNINS
Sbjct  473  LDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINS  532

Query  532  PKQLGVVLFETLQLP--VIKKTKTGYSTAVDVLEQLQGEHPIIDYILEYRQLSKLQSTYV  589
            PKQLG +LFE +QLP  + KKTKTGYSTAVDVLE+L    PI+  IL+YRQ++KLQSTYV
Sbjct  533  PKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYV  592

Query  590  EGLQKVISDDQRIHTRFNQTLAQTGRLSSVDPNLQNIPVRLEEGRKIRKAFKPTSKDSVI  649
             GLQ  I  D +IHTR+ Q L+QTGRLSSVDPNLQNIP+RLE+GR IRKAF P+  D+V+
Sbjct  593  IGLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVL  652

Query  650  LSADYSQIELRVLAHITQDESMKEAFINGDDIHTATAMKVFGVE-ADQVDSLMRRQAKAV  708
            LS+DYSQIELRVLAHI+ DE +  AF +G DIHT+TAM+VFG++ A +V +  RR+AKAV
Sbjct  653  LSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAV  712

Query  709  NFGIVYGISDYGLSQSLGITRKKAKAFIDDYLASFPGVKQYMSDIVKDAKALGYVETLLH  768
            NFGIVYGISD+GLS++LGITRK++K++ID Y+  +PG+K YM ++V++AK  GYVETL+ 
Sbjct  713  NFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFK  772

Query  769  RRRYIPDITSRNFNLRGFAERTAMNTPIQGSAADIIKLAMVKFAQKMKETTYQAKLLLQV  828
            RRR +PDI SRNFN+R+FAERTA+N+PIQGSAADI+K+AM+++ + ++   ++AK+LLQV
Sbjct  773  RRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQV  832

Query  829  HDELIFEVPKsevdsfsefveeIMENALQLDVPLKVDSSYGATWYDAK  876
            HDE+++EVP+ E+ ++  +V + ME A++L VPL VD S G +WY+AK
Sbjct  833  HDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

347) polA in NC_022222


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  677 bits (2558),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 427/888 (49%), Positives = 637/888 (72%), Gaps = 25/888 (2%)

Query  2    NKLVLIDGNSLSFRAFYAL----PLLSNKAGIHTNAVYGFAMLLEKILKEEKPNHFLVAF  57
            NKL+LIDG+S++FRAF+AL      + N +G+HTNA+YGF ++L+ ++K  +P H LVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  58   DAGKTTFRHEKYSEYKGGRQKTPPELSEQFPYIRQLLDAYHIKRYELDNYEADDIIGTLS  117
            DAGKTTFR E Y++YK+GR KTP E+ EQF+YIR++L A  I  YEL++YEADDIIGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  118  KEADKAG--FQTIIITGDRDLTQLATDNVTIYYTKKGVTDVDHYTPDFIAEKYNGLTPNQ  175
            K A+++   F+  I++GD+DL QL+ +N  +  +KKGV++ +++TP ++ EK  GLTPNQ
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEK-MGLTPNQ  183

Query  176  IIDMKGLMGDTSDNIPGVAGVGEKTAIKLLNQFDSVEGVYEHLDEISGKKLKEKLQNSKE  235
            +ID+K+LMGD SDNIPGV+ +GEKT++KLL++F+S+EG+YEH+D +   K+KE+L N ++
Sbjct  184  FIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRD  243

Query  236  DALMSKELATINVDSPIEVKLEDTLMTHQDeqqekielfkklefkqllADIDQSASVEDA  295
            +A++SK LATIN  SPI + L+D +    D              +   + +    + E  
Sbjct  244  QAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKG-LASQMPQEPV  302

Query  296  IEKTFEIETSFDNVDFTSLKEAAIHFELEGGNYLRNNILKFSLFTGEKHIVINAD----D  351
               +++  T+     F++  E  + FE   +NY R+ I+ F+   GE +I  ++D     
Sbjct  303  AVISYQEVTNVSADLFSA--EDIFYFETLRDNYHREAIIGFAWGHGE-QIYASTDLSLLA  359

Query  352  INNYAELVSWLENPNTKKVVYDAKKTYVASHRLGIDIQNISFDIMLASYIIDPSRTISDV  411
             +++ ++   +++P +    YD K++ V   +LGI++   S+D  LA+Y++      +++
Sbjct  360  TDSFKQV---FQKPIA---TYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NEL  412

Query  412  QSVVSLYGQSFVKDDVSIYGKGKKFKVPEDDVLNPYVASITDAIYFVKPNMDKQLEEYNQ  471
             ++  ++ +  + +D ++YGKG K  VP+ DVL   +A     +   K++M  +L   +Q
Sbjct  413  STIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQ  472

Query  472  VELLADLELPLAKILSEMEEIGIYTDVHDLEEMEKEIQEKLDVLIRNIHDAAGEDFNINS  531
            ++L  ++ELPLA++L+ ME  GI  +   L++M  + +  ++ L ++I D AG++FNINS
Sbjct  473  LDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINS  532

Query  532  PKQLGVVLFETLQLP--VIKKTKTGYSTAVDVLEQLQGEHPIIDYILEYRQLSKLQSTYV  589
            PKQLG +LFE +QLP  + KKTKTGYSTAVDVLE+L    PI+  IL+YRQ++KLQSTYV
Sbjct  533  PKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYV  592

Query  590  EGLQKVISDDQRIHTRFNQTLAQTGRLSSVDPNLQNIPVRLEEGRKIRKAFKPTSKDSVI  649
             GLQ  I  D +IHTR+ Q L+QTGRLSSVDPNLQNIP+RLE+GR IRKAF P+  D+V+
Sbjct  593  IGLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVL  652

Query  650  LSADYSQIELRVLAHITQDESMKEAFINGDDIHTATAMKVFGVE-ADQVDSLMRRQAKAV  708
            LS+DYSQIELRVLAHI+ DE +  AF +G DIHT+TAM+VFG++ A +V +  RR+AKAV
Sbjct  653  LSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAV  712

Query  709  NFGIVYGISDYGLSQSLGITRKKAKAFIDDYLASFPGVKQYMSDIVKDAKALGYVETLLH  768
            NFGIVYGISD+GLS++LGITRK++K++ID Y+  +PG+K YM ++V++AK  GYVETL+ 
Sbjct  713  NFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFK  772

Query  769  RRRYIPDITSRNFNLRGFAERTAMNTPIQGSAADIIKLAMVKFAQKMKETTYQAKLLLQV  828
            RRR +PDI SRNFN+R+FAERTA+N+PIQGSAADI+K+AM+++ + ++   ++AK+LLQV
Sbjct  773  RRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQV  832

Query  829  HDELIFEVPKsevdsfsefveeIMENALQLDVPLKVDSSYGATWYDAK  876
            HDE+++EVP+ E+ ++  +V + ME A++L VPL VD S G +WY+AK
Sbjct  833  HDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

348) M013TW_1703 in NC_016928


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  677 bits (2558),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 427/888 (49%), Positives = 637/888 (72%), Gaps = 25/888 (2%)

Query  2    NKLVLIDGNSLSFRAFYAL----PLLSNKAGIHTNAVYGFAMLLEKILKEEKPNHFLVAF  57
            NKL+LIDG+S++FRAF+AL      + N +G+HTNA+YGF ++L+ ++K  +P H LVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  58   DAGKTTFRHEKYSEYKGGRQKTPPELSEQFPYIRQLLDAYHIKRYELDNYEADDIIGTLS  117
            DAGKTTFR E Y++YK+GR KTP E+ EQF+YIR++L A  I  YEL++YEADDIIGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  118  KEADKAG--FQTIIITGDRDLTQLATDNVTIYYTKKGVTDVDHYTPDFIAEKYNGLTPNQ  175
            K A+++   F+  I++GD+DL QL+ +N  +  +KKGV++ +++TP ++ EK  GLTPNQ
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEK-MGLTPNQ  183

Query  176  IIDMKGLMGDTSDNIPGVAGVGEKTAIKLLNQFDSVEGVYEHLDEISGKKLKEKLQNSKE  235
            +ID+K+LMGD SDNIPGV+ +GEKT++KLL++F+S+EG+YEH+D +   K+KE+L N ++
Sbjct  184  FIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRD  243

Query  236  DALMSKELATINVDSPIEVKLEDTLMTHQDeqqekielfkklefkqllADIDQSASVEDA  295
            +A++SK LATIN  SPI + L+D +    D              +   + +    + E  
Sbjct  244  QAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKG-LASQMPQEPV  302

Query  296  IEKTFEIETSFDNVDFTSLKEAAIHFELEGGNYLRNNILKFSLFTGEKHIVINAD----D  351
               +++  T+     F++  E  + FE   +NY R+ I+ F+   GE +I  ++D     
Sbjct  303  AVISYQEVTNVSADLFSA--EDIFYFETLRDNYHREAIIGFAWGHGE-QIYASTDLSLLA  359

Query  352  INNYAELVSWLENPNTKKVVYDAKKTYVASHRLGIDIQNISFDIMLASYIIDPSRTISDV  411
             +++ ++   +++P +    YD K++ V   +LGI++   S+D  LA+Y++      +++
Sbjct  360  TDSFKQV---FQKPIA---TYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NEL  412

Query  412  QSVVSLYGQSFVKDDVSIYGKGKKFKVPEDDVLNPYVASITDAIYFVKPNMDKQLEEYNQ  471
             ++  ++ +  + +D ++YGKG K  VP+ DVL   +A     +   K++M  +L   +Q
Sbjct  413  STIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQ  472

Query  472  VELLADLELPLAKILSEMEEIGIYTDVHDLEEMEKEIQEKLDVLIRNIHDAAGEDFNINS  531
            ++L  ++ELPLA++L+ ME  GI  +   L++M  + +  ++ L ++I D AG++FNINS
Sbjct  473  LDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINS  532

Query  532  PKQLGVVLFETLQLP--VIKKTKTGYSTAVDVLEQLQGEHPIIDYILEYRQLSKLQSTYV  589
            PKQLG +LFE +QLP  + KKTKTGYSTAVDVLE+L    PI+  IL+YRQ++KLQSTYV
Sbjct  533  PKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYV  592

Query  590  EGLQKVISDDQRIHTRFNQTLAQTGRLSSVDPNLQNIPVRLEEGRKIRKAFKPTSKDSVI  649
             GLQ  I  D +IHTR+ Q L+QTGRLSSVDPNLQNIP+RLE+GR IRKAF P+  D+V+
Sbjct  593  IGLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVL  652

Query  650  LSADYSQIELRVLAHITQDESMKEAFINGDDIHTATAMKVFGVE-ADQVDSLMRRQAKAV  708
            LS+DYSQIELRVLAHI+ DE +  AF +G DIHT+TAM+VFG++ A +V +  RR+AKAV
Sbjct  653  LSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAV  712

Query  709  NFGIVYGISDYGLSQSLGITRKKAKAFIDDYLASFPGVKQYMSDIVKDAKALGYVETLLH  768
            NFGIVYGISD+GLS++LGITRK++K++ID Y+  +PG+K YM ++V++AK  GYVETL+ 
Sbjct  713  NFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFK  772

Query  769  RRRYIPDITSRNFNLRGFAERTAMNTPIQGSAADIIKLAMVKFAQKMKETTYQAKLLLQV  828
            RRR +PDI SRNFN+R+FAERTA+N+PIQGSAADI+K+AM+++ + ++   ++AK+LLQV
Sbjct  773  RRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQV  832

Query  829  HDELIFEVPKsevdsfsefveeIMENALQLDVPLKVDSSYGATWYDAK  876
            HDE+++EVP+ E+ ++  +V + ME A++L VPL VD S G +WY+AK
Sbjct  833  HDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

349) polA in NC_022443


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  677 bits (2558),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 427/888 (49%), Positives = 637/888 (72%), Gaps = 25/888 (2%)

Query  2    NKLVLIDGNSLSFRAFYAL----PLLSNKAGIHTNAVYGFAMLLEKILKEEKPNHFLVAF  57
            NKL+LIDG+S++FRAF+AL      + N +G+HTNA+YGF ++L+ ++K  +P H LVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  58   DAGKTTFRHEKYSEYKGGRQKTPPELSEQFPYIRQLLDAYHIKRYELDNYEADDIIGTLS  117
            DAGKTTFR E Y++YK+GR KTP E+ EQF+YIR++L A  I  YEL++YEADDIIGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  118  KEADKAG--FQTIIITGDRDLTQLATDNVTIYYTKKGVTDVDHYTPDFIAEKYNGLTPNQ  175
            K A+++   F+  I++GD+DL QL+ +N  +  +KKGV++ +++TP ++ EK  GLTPNQ
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEK-MGLTPNQ  183

Query  176  IIDMKGLMGDTSDNIPGVAGVGEKTAIKLLNQFDSVEGVYEHLDEISGKKLKEKLQNSKE  235
            +ID+K+LMGD SDNIPGV+ +GEKT++KLL++F+S+EG+YEH+D +   K+KE+L N ++
Sbjct  184  FIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRD  243

Query  236  DALMSKELATINVDSPIEVKLEDTLMTHQDeqqekielfkklefkqllADIDQSASVEDA  295
            +A++SK LATIN  SPI + L+D +    D              +   + +    + E  
Sbjct  244  QAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKG-LASQMPQEPV  302

Query  296  IEKTFEIETSFDNVDFTSLKEAAIHFELEGGNYLRNNILKFSLFTGEKHIVINAD----D  351
               +++  T+     F++  E  + FE   +NY R+ I+ F+   GE +I  ++D     
Sbjct  303  AVISYQEVTNVSADLFSA--EDIFYFETLRDNYHREAIIGFAWGHGE-QIYASTDLSLLA  359

Query  352  INNYAELVSWLENPNTKKVVYDAKKTYVASHRLGIDIQNISFDIMLASYIIDPSRTISDV  411
             +++ ++   +++P +    YD K++ V   +LGI++   S+D  LA+Y++      +++
Sbjct  360  TDSFKQV---FQKPIA---TYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NEL  412

Query  412  QSVVSLYGQSFVKDDVSIYGKGKKFKVPEDDVLNPYVASITDAIYFVKPNMDKQLEEYNQ  471
             ++  ++ +  + +D ++YGKG K  VP+ DVL   +A     +   K++M  +L   +Q
Sbjct  413  STIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQ  472

Query  472  VELLADLELPLAKILSEMEEIGIYTDVHDLEEMEKEIQEKLDVLIRNIHDAAGEDFNINS  531
            ++L  ++ELPLA++L+ ME  GI  +   L++M  + +  ++ L ++I D AG++FNINS
Sbjct  473  LDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINS  532

Query  532  PKQLGVVLFETLQLP--VIKKTKTGYSTAVDVLEQLQGEHPIIDYILEYRQLSKLQSTYV  589
            PKQLG +LFE +QLP  + KKTKTGYSTAVDVLE+L    PI+  IL+YRQ++KLQSTYV
Sbjct  533  PKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYV  592

Query  590  EGLQKVISDDQRIHTRFNQTLAQTGRLSSVDPNLQNIPVRLEEGRKIRKAFKPTSKDSVI  649
             GLQ  I  D +IHTR+ Q L+QTGRLSSVDPNLQNIP+RLE+GR IRKAF P+  D+V+
Sbjct  593  IGLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVL  652

Query  650  LSADYSQIELRVLAHITQDESMKEAFINGDDIHTATAMKVFGVE-ADQVDSLMRRQAKAV  708
            LS+DYSQIELRVLAHI+ DE +  AF +G DIHT+TAM+VFG++ A +V +  RR+AKAV
Sbjct  653  LSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAV  712

Query  709  NFGIVYGISDYGLSQSLGITRKKAKAFIDDYLASFPGVKQYMSDIVKDAKALGYVETLLH  768
            NFGIVYGISD+GLS++LGITRK++K++ID Y+  +PG+K YM ++V++AK  GYVETL+ 
Sbjct  713  NFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFK  772

Query  769  RRRYIPDITSRNFNLRGFAERTAMNTPIQGSAADIIKLAMVKFAQKMKETTYQAKLLLQV  828
            RRR +PDI SRNFN+R+FAERTA+N+PIQGSAADI+K+AM+++ + ++   ++AK+LLQV
Sbjct  773  RRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQV  832

Query  829  HDELIFEVPKsevdsfsefveeIMENALQLDVPLKVDSSYGATWYDAK  876
            HDE+++EVP+ E+ ++  +V + ME A++L VPL VD S G +WY+AK
Sbjct  833  HDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

350) polA in NC_022442


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  677 bits (2558),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 427/888 (49%), Positives = 637/888 (72%), Gaps = 25/888 (2%)

Query  2    NKLVLIDGNSLSFRAFYAL----PLLSNKAGIHTNAVYGFAMLLEKILKEEKPNHFLVAF  57
            NKL+LIDG+S++FRAF+AL      + N +G+HTNA+YGF ++L+ ++K  +P H LVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  58   DAGKTTFRHEKYSEYKGGRQKTPPELSEQFPYIRQLLDAYHIKRYELDNYEADDIIGTLS  117
            DAGKTTFR E Y++YK+GR KTP E+ EQF+YIR++L A  I  YEL++YEADDIIGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  118  KEADKAG--FQTIIITGDRDLTQLATDNVTIYYTKKGVTDVDHYTPDFIAEKYNGLTPNQ  175
            K A+++   F+  I++GD+DL QL+ +N  +  +KKGV++ +++TP ++ EK  GLTPNQ
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEK-MGLTPNQ  183

Query  176  IIDMKGLMGDTSDNIPGVAGVGEKTAIKLLNQFDSVEGVYEHLDEISGKKLKEKLQNSKE  235
            +ID+K+LMGD SDNIPGV+ +GEKT++KLL++F+S+EG+YEH+D +   K+KE+L N ++
Sbjct  184  FIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRD  243

Query  236  DALMSKELATINVDSPIEVKLEDTLMTHQDeqqekielfkklefkqllADIDQSASVEDA  295
            +A++SK LATIN  SPI + L+D +    D              +   + +    + E  
Sbjct  244  QAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKG-LASQMPQEPV  302

Query  296  IEKTFEIETSFDNVDFTSLKEAAIHFELEGGNYLRNNILKFSLFTGEKHIVINAD----D  351
               +++  T+     F++  E  + FE   +NY R+ I+ F+   GE +I  ++D     
Sbjct  303  AVISYQEVTNVSADLFSA--EDIFYFETLRDNYHREAIIGFAWGHGE-QIYASTDLSLLA  359

Query  352  INNYAELVSWLENPNTKKVVYDAKKTYVASHRLGIDIQNISFDIMLASYIIDPSRTISDV  411
             +++ ++   +++P +    YD K++ V   +LGI++   S+D  LA+Y++      +++
Sbjct  360  TDSFKQV---FQKPIA---TYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NEL  412

Query  412  QSVVSLYGQSFVKDDVSIYGKGKKFKVPEDDVLNPYVASITDAIYFVKPNMDKQLEEYNQ  471
             ++  ++ +  + +D ++YGKG K  VP+ DVL   +A     +   K++M  +L   +Q
Sbjct  413  STIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQ  472

Query  472  VELLADLELPLAKILSEMEEIGIYTDVHDLEEMEKEIQEKLDVLIRNIHDAAGEDFNINS  531
            ++L  ++ELPLA++L+ ME  GI  +   L++M  + +  ++ L ++I D AG++FNINS
Sbjct  473  LDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINS  532

Query  532  PKQLGVVLFETLQLP--VIKKTKTGYSTAVDVLEQLQGEHPIIDYILEYRQLSKLQSTYV  589
            PKQLG +LFE +QLP  + KKTKTGYSTAVDVLE+L    PI+  IL+YRQ++KLQSTYV
Sbjct  533  PKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYV  592

Query  590  EGLQKVISDDQRIHTRFNQTLAQTGRLSSVDPNLQNIPVRLEEGRKIRKAFKPTSKDSVI  649
             GLQ  I  D +IHTR+ Q L+QTGRLSSVDPNLQNIP+RLE+GR IRKAF P+  D+V+
Sbjct  593  IGLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVL  652

Query  650  LSADYSQIELRVLAHITQDESMKEAFINGDDIHTATAMKVFGVE-ADQVDSLMRRQAKAV  708
            LS+DYSQIELRVLAHI+ DE +  AF +G DIHT+TAM+VFG++ A +V +  RR+AKAV
Sbjct  653  LSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAV  712

Query  709  NFGIVYGISDYGLSQSLGITRKKAKAFIDDYLASFPGVKQYMSDIVKDAKALGYVETLLH  768
            NFGIVYGISD+GLS++LGITRK++K++ID Y+  +PG+K YM ++V++AK  GYVETL+ 
Sbjct  713  NFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFK  772

Query  769  RRRYIPDITSRNFNLRGFAERTAMNTPIQGSAADIIKLAMVKFAQKMKETTYQAKLLLQV  828
            RRR +PDI SRNFN+R+FAERTA+N+PIQGSAADI+K+AM+++ + ++   ++AK+LLQV
Sbjct  773  RRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQV  832

Query  829  HDELIFEVPKsevdsfsefveeIMENALQLDVPLKVDSSYGATWYDAK  876
            HDE+++EVP+ E+ ++  +V + ME A++L VPL VD S G +WY+AK
Sbjct  833  HDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

351) Bcell_3214 in NC_014829


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  677 bits (2558),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 423/885 (48%), Positives = 645/885 (73%), Gaps = 21/885 (2%)

Query  2    NKLVLVDGNSIAYRAFFAL----PLLNNEKGVFTNAVYGFTTMLLKILEEEKPTHMLVAF  57
            NKL+L+DG+S+A+RAFFAL      ++N+ G+ TNA+YGF  ML  ++   +PTH+LVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  58   DAGKTTFRHNTYKEYKGKRQKTPGELAEQLPVMRDLLKAFNITYYEVENYEADDIIGTLS  117
            DAGKTTFR + Y +YK+ R KTP+E+ EQ++ +R++L A+ I+YYE+E+YEADDIIGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  118  TKASKSN--WEVKIVSGDKDLLQLVSENVKVALTRKGITNVDTYDLQMIDEKYGIKPEQI  175
              A +++   +V IVSGDKDL+QL  EN  V +++KG+++ + +    + EK G+ P+Q+
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  176  IDMKGLMGDASDNIPGVPGVGEKTALKLLKQFGTVEKLYESLEDVSGKKLKEKLAENKDN  235
            ID+K+LMGD SDNIPGV  +GEKT+LKLL +FG++E +YE +++    K+KE+L +++D+
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRDQ  244

Query  236  AFMSKKLATIELNSPVTIDFEDTKLTDPNNKEVTALFKELEFNSLLERIDQEEEAEQPLV  295
            AF+SK LATI+  SP+TI+++D    +P+   ++ ++ E++F  L   +   + +++P+ 
Sbjct  245  AFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLA-SQMPQEPVA  303

Query  296  DVDVEVVHTITEDMLYSPSAIVVEVLEENYHNAEIVGIS--IVNEVGSYYIPTEVAI-NS  352
             +  + V  ++ D++ +   +  E L +NYH   I+G++    +++   Y +T++++  +
Sbjct  304  VISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQI---YASTDLSLLAT  360

Query  353  DMFKKWANDEKNEKWIFNAKQAIVSLGWNDISLRGVTFDIQIASYLIDPSASSHEMADIS  412
            D FK+  +        ++ K++ V L+  +I L + ++D ++A+YL+ ++   +E++ I+
Sbjct  361  DSFKQVFQKPIA---TYDFKRSKVLLSHLGIELVAPSYDARLANYLL-STVEDNELSTIA  416

Query  413  NRKRSYTVKSDEAVYGKGKKRQVPEEEIVAQHLVRKAAAINVlkeeleselkeneqfelF  472
                  ++  D++VYGKG KR VP+ +++ +HL RK   +   K ++   L  +EQ++L+
Sbjct  417  RIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLY  476

Query  473  KDLEMPLSIVLGHMEMNGISINKEELLQMGETLSDKLSTMEKEIHELAGVEFNINSPKQL  532
            +++E+PL+ VL+ ME++GI +N+  L +M+E     + ++ +EI ++AG EFNINSPKQL
Sbjct  477  QNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQL  536

Query  533  GEILFDKLQLP--VVKKTKTGYSTSADVLEQLRDKHEIVEKILLYRQLGKLNSTYIEGLL  590
            G ILF+K+QLP  + KKTKTGYST+ DVLE+L     IV KIL YRQ+ KL+STY+ GL 
Sbjct  537  GSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQ  596

Query  591  KVIHQKSGKIHTIFNQALTQTGRLSSTEPNLQNIPIRLEEGRKIRRAFVPERENAVIFAA  650
              I    GKIHT + Q LTQTGRLSS +PNLQNIPIRLE+GR IR+AF P +E+AV++++
Sbjct  597  DYILA-DGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSS  655

Query  651  DYSQIELRVLAHISNDENLTNAFKENMDVHTKTAMDVFHVS-ADEVTSLMRRTAKAVNFG  709
            DYSQIELRVLAHIS DE+L  AF+E  D+HT TAM VF +  A +VT+  RR AKAVNFG
Sbjct  656  DYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFG  715

Query  710  IVYGISDYGLSQNLGITRKEAKKFIDRYFDSYPGVKEYMESIVEEARVNGYVTTMLHRRR  769
            IVYGISD+GLS+NLGITRK++K +ID YF+ YPG+K YME++V EA+ +GYV T++ RRR
Sbjct  716  IVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRR  775

Query  770  YLPEITSRNFNLRSFAERTAMNTPIQGSAADIIkkamvkmeeemkekGLKSTLLLQVHDE  829
             LP+I SRNFN+RSFAERTA+N+PIQGSAADI+K AM++++  ++  G+++ +LLQVHDE
Sbjct  776  ELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDE  835

Query  830  LIFEVVQEEIETMKELVPKVMENAVNLAVPLKVDFSFGDTWYDAK  874
            +++EV ++E+ ++K LV   ME AV+LAVPL VD S G++WY+AK
Sbjct  836  IVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

352) polA in NC_021554


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  677 bits (2560),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 426/888 (48%), Positives = 638/888 (72%), Gaps = 25/888 (2%)

Query  2    NKLVLIDGNSLSFRAFYAL----PLLSNKAGIHTNAVYGFAMLLEKILKEEKPNHFLVAF  57
            NKL+LIDG+S++FRAF+AL      + N +G+HTNA+YGF ++L+ ++K  +P H LVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  58   DAGKTTFRHEKYSEYKGGRQKTPPELSEQFPYIRQLLDAYHIKRYELDNYEADDIIGTLS  117
            DAGKTTFR E Y++YK+GR KTP E+ EQF+YIR++L A  I  YEL++YEADDIIGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  118  KEADKAG--FQTIIITGDRDLTQLATDNVTIYYTKKGVTDVDHYTPDFIAEKYNGLTPNQ  175
            K A+++   F+  I++GD+DL QL+ +N  +  +KKGV++ +++TP ++ EK  GLTPNQ
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEK-MGLTPNQ  183

Query  176  IIDMKGLMGDTSDNIPGVAGVGEKTAIKLLNQFDTVEGVYEHLDEISGKKLKEKLQNSKE  235
            +ID+K+LMGD SDNIPGV+ +GEKT++KLL++F+++EG+YEH+D +   K+KE+L N ++
Sbjct  184  FIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRD  243

Query  236  DALMSKELATINVDSPIEVKLEDTLMTHQDeqqekielfkklefkqllADIDQSASVEDA  295
            +A++SK LATIN  SPI + L+D +    D              +   + +    + E  
Sbjct  244  QAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKG-LASQMPQEPV  302

Query  296  IEKTFEIETSFDNVDFTSLKEAAIHFELDGGNYLRNNILKFSLFTGEKHIVINAD----D  351
               +++  T+     F++  E  + FE   +NY R+ I+ F+   GE +I  ++D     
Sbjct  303  AVISYQEVTNVSADLFSA--EDIFYFETLRDNYHREAIIGFAWGHGE-QIYASTDLSLLA  359

Query  352  INNYAELVSWLENPNTKKVVYDAKKTYVASHRLGIDIQNISFDIMLASYIIDPSRTISDV  411
             +++ ++   +++P +    YD K++ V   +LGI++   S+D  LA+Y++      +++
Sbjct  360  TDSFKQV---FQKPIA---TYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NEL  412

Query  412  QSVVSLYGQSFVKDDVSIYGKGKKFKVPEDDVLNPYVASITDAIYFAKPNMDKQLEEYNQ  471
             ++  ++ +  + +D ++YGKG K  VP+ DVL   +A     +  +K++M  +L   +Q
Sbjct  413  STIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQ  472

Query  472  VELLADLELPLAKILSEMEEIGIYTDVHDLEEMEKEIQEKLDVLIRNIHDAAGEDFNINS  531
            ++L  ++ELPLA++L+ ME  GI  +   L++M  + +  ++ L ++I D AG++FNINS
Sbjct  473  LDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINS  532

Query  532  PKQLGVVLFETLQLP--VIKKTKTGYSTAVDVLEQLQGEHPIIDYILEYRQLSKLQSTYV  589
            PKQLG +LFE +QLP  + KKTKTGYSTAVDVLE+L    PI+  IL+YRQ++KLQSTYV
Sbjct  533  PKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYV  592

Query  590  EGLQKVISDDQRIHTRFNQTLAQTGRLSSVDPNLQNIPVRLEEGRKIRKAFKPTSKDSVI  649
             GLQ  I  D +IHTR+ Q L+QTGRLSSVDPNLQNIP+RLE+GR IRKAF P+  D+V+
Sbjct  593  IGLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVL  652

Query  650  LSADYSQIELRVLAHITQDESMKEAFINGDDIHTATAMKVFGVE-ADQVDSLMRRQAKAV  708
            LS+DYSQIELRVLAHI+ DE +  AF +G DIHT+TAM+VFG++ A +V +  RR+AKAV
Sbjct  653  LSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAV  712

Query  709  NFGIVYGISDYGLSQSLGITRKKAKAFIDDYLASFPGVKQYMSDIVKDAKALGYVETLLH  768
            NFGIVYGISD+GLS++LGITRK++K++ID Y+  +PG+K YM ++V++AK  GYVETL+ 
Sbjct  713  NFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFK  772

Query  769  RRRYIPDITSRNFNLRGFAERTAMNTPIQGSAADIIKLAMVKFAQKMKETTYQAKLLLQV  828
            RRR +PDI SRNFN+R+FAERTA+N+PIQGSAADI+K+AM+++ + ++   ++AK+LLQV
Sbjct  773  RRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQV  832

Query  829  HDELIFEVPKsevdsfsefveeIMENALQLDVPLKVDSSYGATWYDAK  876
            HDE+++EVP+ E+ ++  +V + ME A++L VPL VD S G +WY+AK
Sbjct  833  HDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

353) polA in NC_002952


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  677 bits (2558),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 424/884 (48%), Positives = 633/884 (72%), Gaps = 17/884 (1%)

Query  2    NKLVLIDGNSLSFRAFYAL----PLLSNKAGIHTNAVYGFAMLLEKILKEEKPNHFLVAF  57
            NKL+LIDG+S++FRAF+AL      + N +G+HTNA+YGF ++L+ ++K  +P H LVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  58   DAGKTTFRHEKYSEYKGGRQKTPPELSEQFPYIRQLLDAYHIKRYELDNYEADDIIGTLS  117
            DAGKTTFR E Y++YK+GR KTP E+ EQF+YIR++L A  I  YEL++YEADDIIGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  118  KEADKAG--FQTIIITGDRDLTQLATDNVTIYYTKKGVTDVDHYTPDFIAEKYNGLTPNQ  175
            K A+++   F+  I++GD+DL QL+ +N  +  +KKGV++ +++TP ++ EK  GLTPNQ
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEK-MGLTPNQ  183

Query  176  IIDMKGLMGDTSDNIPGVAGVGEKTAIKLLNQFDTVEGVYEHLDEISGKKLKEKLQNSKE  235
            +ID+K+LMGD SDNIPGV+ +GEKT++KLL++F+++EG+YEH+D +   K+KE+L N ++
Sbjct  184  FIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRD  243

Query  236  NALMSKELATINVDSPIEVKLEDTLMTHQDeqqekielfkklefkqllADIDQSASGEDA  295
            +A++SK LATIN  SPI + L+D +    D              +   +   Q +    A
Sbjct  244  QAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEPVA  303

Query  296  IEKTFEIETSFDNVDFTSLKEATIHFELDGGNYLRNNILKFSLFTGEKHIVINADDIINY  355
            +  +++  T+     F++  E  + FE   +NY R+ I+ F+   GE+        ++  
Sbjct  304  V-ISYQEVTNVSADLFSA--EDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLAT  360

Query  356  AELVSWLENPNTKKVVYDAKKTYVASHRLGIDIQNISFDIMLASYIIDPSRTISDVQSVV  415
              +   +++P +    YD K++ V   +LGI++   S+D  LA+Y++      +++ ++ 
Sbjct  361  DSFKQVFQKPIA---TYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NELSTIA  416

Query  416  SLYGQSFVKDDVSIYGKGKKFKVPEDDVLNPYVASITDAIYFAKPNMDKQLEEYNQVELL  475
             ++ +  + +D ++YGKG K  VP+ DVL   +A     +  +K++M  +L   +Q++L 
Sbjct  417  RIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLY  476

Query  476  ADLELPLAKILSEMEEIGIYTDVHDLEEMEKEIQEKLDVLIRNIHDAAGEDFNINSPKQL  535
             ++ELPLA++L+ ME  GI  +   L++M  + +  ++ L ++I D AG++FNINSPKQL
Sbjct  477  QNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQL  536

Query  536  GVVLFETLQLP--VIKKTKTGYSTAVDVLEQLQGEHPIIDYILEYRQLSKLQSTYVEGLQ  593
            G +LFE +QLP  + KKTKTGYSTAVDVLE+L    PI+  IL+YRQ++KLQSTYV GLQ
Sbjct  537  GSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQ  596

Query  594  KVISDDQRIHTRFNQTLAQTGRLSSVDPNLQNIPVRLEEGRKIRKAFKPTSKDSVILSAD  653
              I  D +IHTR+ Q L+QTGRLSSVDPNLQNIP+RLE+GR IRKAF P+  D+V+LS+D
Sbjct  597  DYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSD  656

Query  654  YSQIELRVLAHITQDESMKEAFINGDDIHTATAMKVFGVE-ADQVDSLMRRQAKAVNFGI  712
            YSQIELRVLAHI+ DE +  AF +G DIHT+TAM+VFG++ A +V +  RR+AKAVNFGI
Sbjct  657  YSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGI  716

Query  713  VYGISDYGLSQSLGITRKKAKAFIDDYLASFPGVKQYMSDIVKDAKALGFVETLLHRRRY  772
            VYGISD+GLS++LGITRK++K++ID Y+  +PG+K YM ++V++AK  G+VETL+ RRR 
Sbjct  717  VYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRE  776

Query  773  IPDITSRNFNLRGFAERTAMNTPIQGSAADIIKLAMVKFAQKMKETTYQAKLLLQVHDEL  832
            +PDI SRNFN+R+FAERTA+N+PIQGSAADI+K+AM+++ + ++   ++AK+LLQVHDE+
Sbjct  777  LPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEI  836

Query  833  IFEVPKsevdsfsefveeIMENALQLDVPLKVDSSYGATWYDAK  876
            ++EVP+ E+ ++  +V + ME A++L VPL VD S G +WY+AK
Sbjct  837  VLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

354) polA in NC_021362


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  676 bits (2556),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 439/888 (50%), Positives = 637/888 (72%), Gaps = 17/888 (1%)

Query  1    MTERKKLVLVDGNSLAYRAFFAL----PLLSNEKGIHTNAVYGFTTILMKMLEEEKPTHM  56
            M +++KL+L+DG+S+A+RAFFAL      + N+ G+HTNA+YGF  +L  M+   +PTH+
Sbjct  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60

Query  57   LVAFDAGKTTFRHKTFKEYKGGRQKTPPELSEQLPFIRELLDAYQISRYELENYEADDII  116
            LVAFDAGKTTFR   + +YK+GR KTP E+ EQ+++IRE+L A  I+ YELE+YEADDII
Sbjct  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120

Query  117  GTLAKSAEKDG--FEVKIFSGDKDLTQLATEGTTVAITKKGITDVEYYTPEHVREKYGLT  174
            GTL K AE+    F+V I SGDKDL QL+ E T V I+KKG+++ E +TP  + EK GLT
Sbjct  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180

Query  175  PEQIIDMKGLMGDSSDNIPGVPGVGEKTAIKLLKQFHTVEELLSSIDEVSGkklkeklee  234
            P+Q+ID+K+LMGD SDNIPGV  +GEKT++KLL +F ++E +   ID     K+KE+L +
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  235  fkeQALMSKELATITTEAPLEVTLDSLGYEGFDREAVVKIFKDLGFNSLLerigeepgek  294
             ++QA++SK LATI T +P+ + LD + Y+G D  ++ +++ +++F  L   ++ +  + 
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQE  300

Query  295  eeeqfeeINVTIKTDITDDLFASPASLVVEQLGDNYHEAPILGFSIVNEHGAFFIPEETA  354
                +   +VT   +++ DLF++   +  E L DNYH  +I+GF+  + +  +   + + 
Sbjct  301  PVAVISYQEVT---NVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSL  357

Query  355  VQSDRFKEWAEDESKKKWVFDAKRAAVALRWRGIELKGAEFDVLLAAYIINPGHSYDDVA  414
            + +D FK+  +   K    +D KR+ V L   GIEL ++ +D  LA Y+++  +  ++++
Sbjct  358  LATDSFKQVFQ---KPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NELS  413

Query  415  SVAKEHQLHIVAADEAVYGKGAKQAVPDEKELADHLARKAKAISllreklldelekneql  474
            ++A+      +  D++VYGKGAK+AVPD   L +HLARK K +   + ++LD L  +EQL
Sbjct  414  TIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQL  473

Query  475  dlFEALEMPLAHILGEMESIGVQVDVDRLKKMGEELSAKLAEYEKKIHESAGETFNINSP  534
            DL++ +E+PLA++L+ ME  G++V+   L+ M+E+    +    + I + AG+ FNINSP
Sbjct  474  DLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSP  533

Query  535  KQLGVILFEKLGLP--AVKKTKTGYSTSADVLEKLRDKHVIIEDILHYRQIGKLQSTYVE  592
            KQLG ILFEK+ LP    KKTKTGYST+ DVLE+L     I+  IL+YRQI KLQSTYV 
Sbjct  534  KQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVI  593

Query  593  GLLKVIKKDSHKVHTRFNQALTQTGRLSSTDPNLQNIPIRLEEGRKIRQAFVPSQKGWLI  652
            GL   I  D+ K+HTR+ Q LTQTGRLSS DPNLQNIPIRLE+GR IR+AF PS+ + ++
Sbjct  594  GLQDYILADG-KIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVL  652

Query  653  FAADYSQIELRVLAHISKDKNLIEAFTNDMDVHTKTAMDVFHVS-EEEVTPAMRRQAKAV  711
            +++DYSQIELRVLAHIS D +LI AF ++ D+HT TAM VF +    +VT+  RR+AKAV
Sbjct  653  LSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAV  712

Query  712  NFGIVYGISDYGLSQNLGITRKEAAAFIERYFHSFQGVKEYMEETVQEAKQRGYVTTLLS  771
            NFGIVYGISD+GLS+NLGITRK++ ++I+ YF+ + G+K YME+ V+EAK++GYV TL+ 
Sbjct  713  NFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFK  772

Query  772  RRRYIPELTSRNFNLRSFAERTAMNTPIQGSAADIIKKAMIDMADKLKEKNLQAKLLLQV  831
            RRR +P++ SRNFN+RSFAERTA+N+PIQGSAADI+K AMI++   L+   ++AK+LLQV
Sbjct  773  RRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQV  832

Query  832  HDELIFEAPEDEIKVLEKLVPEVMEHALELDVPLKVDCASGPSWYDAK  879
            HDE+++E P+DE+  + KLV + ME A++L VPL VD ++G SWY+AK
Sbjct  833  HDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

355) polA in NC_021670


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  676 bits (2555),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 427/889 (49%), Positives = 638/889 (72%), Gaps = 27/889 (3%)

Query  2    NKLVLIDGNSLSFRAFYAL-----PFLSNKAGIHTNAVYGFAMLLEKILKEEKPNHFLVA  56
            NKL+LIDG+S++FRAF+AL      F  N +G+HTNA+YGF ++L+ ++K  +P H LVA
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRF-KNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVA  63

Query  57   FDAGKTTFRHEKYSEYKGGRQKTPPELSEQFPYIRQLLDAYHIKRYELDNYEADDIIGTL  116
            FDAGKTTFR E Y++YK+GR KTP E+ EQF+YIR++L A  I  YEL++YEADDIIGTL
Sbjct  64   FDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTL  123

Query  117  SKEADKAG--FQTIIITGDRDLTQLATDNVTIYYTKKGVTDVDHYTPDFIAEKYNGLTPN  174
             K A+++   F+  I++GD+DL QL+ +N  +  +KKGV++ +++TP ++ EK  GLTPN
Sbjct  124  DKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEK-MGLTPN  182

Query  175  QIIDMKGLMGDTSDNIPGVAGVGEKTAIKLLNQFDTVEGVYEHLDEISGKKLKEKLQNSK  234
            Q+ID+K+LMGD SDNIPGV+ +GEKT++KLL++F+++EG+YEH+D +   K+KE+L N +
Sbjct  183  QFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDR  242

Query  235  EDALMSKELATINVDSPIEVKLEDTLMTHQDeqqekielfkklefkqllADIDQSASVED  294
            ++A++SK LATIN  SPI + L+D +    D              +   + +    + E 
Sbjct  243  DQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKG-LASQMPQEP  301

Query  295  AIEKTFEIETSFDNIDFTSLKEAAIHFELDGGNYLRNNILKFSLFTGEKHIVINAD----  350
                +++  T+     F++  E  + FE   +NY R+ I+ F+   GE +I  ++D    
Sbjct  302  VAVISYQEVTNVSADLFSA--EDIFYFETLRDNYHREAIIGFAWGHGE-QIYASTDLSLL  358

Query  351  DINNYVELVSWLENPNSKKVVYDAKKTYVASHRLGIDIQNISFDIMLASYIIDPSRTISD  410
              +++ ++   +++P +    YD K++ V   +LGI++   S+D  LA+Y++      ++
Sbjct  359  ATDSFKQV---FQKPIA---TYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NE  411

Query  411  VQSVVSLYGQSFVKDDVSIYGKGKKFKVPEDDVLNPYVASITDAIYFAKPNMDKQLEEYN  470
            + ++  ++ +  + +D ++YGKG K  VP+ DVL   +A     +  +K++M  +L   +
Sbjct  412  LSTIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHE  471

Query  471  QVELLADLELPLAKILSEMEEIGIFTDVHDLEEMEKEIQEKLDVLIRNIHDAAGEDFNIN  530
            Q++L  ++ELPLA++L+ ME  GI  +   L++M  + +  ++ L ++I D AG++FNIN
Sbjct  472  QLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNIN  531

Query  531  SPKQLGVVLFETLQLP--VIKKTKTGYSTAVDVLEQLQGEHPIIDYILEYRQLSKLQSTY  588
            SPKQLG +LFE +QLP  + KKTKTGYSTAVDVLE+L    PI+  IL+YRQ++KLQSTY
Sbjct  532  SPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTY  591

Query  589  VEGLQKVISDDQRIHTRFNQTLAQTGRLSSVDPNLQNIPVRLEEGRKIRKAFKPTSKDSV  648
            V GLQ  I  D +IHTR+ Q L+QTGRLSSVDPNLQNIP+RLE+GR IRKAF P+  D+V
Sbjct  592  VIGLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAV  651

Query  649  ILSADYSQIELRVLAHITQDESMKEAFINGDDIHTATAMKVFGVE-ADQVDSLMRRQAKA  707
            +LS+DYSQIELRVLAHI+ DE +  AF +G DIHT+TAM+VFG++ A +V +  RR+AKA
Sbjct  652  LLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKA  711

Query  708  VNFGIVYGISDYGLSQSLGITRKKAKAFIDDYLASFPGVKQYMSDIVKDAKALGYVETLL  767
            VNFGIVYGISD+GLS++LGITRK++K++ID Y+  +PG+K YM ++V++AK  GYVETL+
Sbjct  712  VNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLF  771

Query  768  HRRRYIPDITSRNFNLRGFAERTAMNTPIQGSAADIIKLAMVKFAQKMKETTYQAKLLLQ  827
             RRR +PDI SRNFN+R+FAERTA+N+PIQGSAADI+K+AM+++ + ++   ++AK+LLQ
Sbjct  772  KRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQ  831

Query  828  VHDELIFEVPKsevdsfsefveeIMENALQLDVPLKVDSSYGATWYDAK  876
            VHDE+++EVP+ E+ ++  +V + ME A++L VPL VD S G +WY+AK
Sbjct  832  VHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

356) polA in NC_017340


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  676 bits (2556),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 426/888 (48%), Positives = 638/888 (72%), Gaps = 25/888 (2%)

Query  2    NKLVLIDGNSLSFRAFYAL----PLLSNKAGIHTNAVYGFAMLLEKILKEEKPNHFLVAF  57
            NKL+LIDG+S++FRAF+AL      + N +G+HTNA+YGF ++L+ ++K  +P H LVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  58   DAGKTTFRHEKYSEYKGGRQKTPPELSEQFPYIRQLLDAYHIKRYELDNYEADDIIGTLS  117
            DAGKTTFR E Y++YK+GR KTP E+ EQF+YIR++L A  I  YEL++YEADDIIGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  118  KEADKAG--FQTIIITGDRDLTQLATDNVTIYYTKKGVTDVDHYTPDFIAEKYNGLTPNQ  175
            K A+++   F+  I++GD+DL QL+ +N  +  +KKGV++ +++TP ++ EK  GLTPNQ
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEK-MGLTPNQ  183

Query  176  IIDMKGLMGDTSDNIPGVAGVGEKTAIKLLNQFDTVEGVYEHLDEISGKKLKEKLQNSKE  235
            +ID+K+LMGD SDNIPGV+ +GEKT++KLL++F+++EG+YEH+D +   K+KE+L N ++
Sbjct  184  FIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRD  243

Query  236  DALMSKELATINVDSPIEVKLEDTLMTHQDeqqekielfkklefkqllSDIDQSASVEDA  295
            +A++SK LATIN  SPI + L+D +    D              +   + +    + E  
Sbjct  244  QAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKG-LASQMPQEPV  302

Query  296  IEKTFEIETSFDNIDFTSLKEAAIHFELDGGNYLRNNILKFSLFTGEKHIVINAD----D  351
               +++  T+     F++  E  + FE   +NY R+ I+ F+   GE +I  ++D     
Sbjct  303  AVISYQEVTNVSADLFSA--EDIFYFETLRDNYHREAIIGFAWGHGE-QIYASTDLSLLA  359

Query  352  INNYAELVSWLENPNTKKVVYDAKKTYVASHRLGIDIQNISFDIMLASYIIDPSRTISDV  411
             +++ ++   +++P +    YD K++ V   +LGI++   S+D  LA+Y++      +++
Sbjct  360  TDSFKQV---FQKPIA---TYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NEL  412

Query  412  QSVVSLYGQSFVKDDVSIYGKGKKFKVPEDDVLNPYVASITDAIYFAKPNMDKQLEEYNQ  471
             ++  ++ +  + +D ++YGKG K  VP+ DVL   +A     +  +K++M  +L   +Q
Sbjct  413  STIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQ  472

Query  472  VELLADLELPLAKILSEMEEIGIFTDVHDLEEMEKEIQEKLDVLIRNIHDAAGEDFNINS  531
            ++L  ++ELPLA++L+ ME  GI  +   L++M  + +  ++ L ++I D AG++FNINS
Sbjct  473  LDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINS  532

Query  532  PKQLGVVLFETLQLP--VIKKTKTGYSTAVDVLEQLQGEHPIIDYILEYRQLSKLQSTYV  589
            PKQLG +LFE +QLP  + KKTKTGYSTAVDVLE+L    PI+  IL+YRQ++KLQSTYV
Sbjct  533  PKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYV  592

Query  590  EGLQKVISDDQRIHTRFNQTLAQTGRLSSVDPNLQNIPVRLEEGRKIRKAFKPTSKDSVI  649
             GLQ  I  D +IHTR+ Q L+QTGRLSSVDPNLQNIP+RLE+GR IRKAF P+  D+V+
Sbjct  593  IGLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVL  652

Query  650  LSADYSQIELRVLAHITQDESMKEAFINGDDIHTATAMKVFGVE-ADQVDSLMRRQAKAV  708
            LS+DYSQIELRVLAHI+ DE +  AF +G DIHT+TAM+VFG++ A +V +  RR+AKAV
Sbjct  653  LSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAV  712

Query  709  NFGIVYGISDYGLSQSLGITRKKAKAFIDDYLASFPGVKQYMSDIVKDAKALGYVETLLH  768
            NFGIVYGISD+GLS++LGITRK++K++ID Y+  +PG+K YM ++V++AK  GYVETL+ 
Sbjct  713  NFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFK  772

Query  769  RRRYIPDITSRNFNLRGFAERTAMNTPIQGSAADIIKLAMVKFAQKMKETTYQAKLLLQV  828
            RRR +PDI SRNFN+R+FAERTA+N+PIQGSAADI+K+AM+++ + ++   ++AK+LLQV
Sbjct  773  RRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQV  832

Query  829  HDELIFEVPKsevdsfsefveeIMENALQLDVPLKVDSSYGATWYDAK  876
            HDE+++EVP+ E+ ++  +V + ME A++L VPL VD S G +WY+AK
Sbjct  833  HDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

357) polA in NC_017351


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  676 bits (2557),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 426/888 (48%), Positives = 638/888 (72%), Gaps = 25/888 (2%)

Query  2    NKLVLIDGNSLSFRAFYAL----PLLSNKAGIHTNAVYGFAMLLEKILKEEKPNHFLVAF  57
            NKL+LIDG+S++FRAF+AL      + N +G+HTNA+YGF ++L+ ++K  +P H LVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  58   DAGKTTFRHEKYSEYKGGRQKTPPELSEQFPYIRQLLDAYHIKRYELDNYEADDIIGTLS  117
            DAGKTTFR E Y++YK+GR KTP E+ EQF+YIR++L A  I  YEL++YEADDIIGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  118  KEADKAG--FQTIIITGDRDLTQLATDNVTIYYTKKGVTDVDHYTPDFIAEKYNGLTPNQ  175
            K A+++   F+  I++GD+DL QL+ +N  +  +KKGV++ +++TP ++ EK  GLTPNQ
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEK-MGLTPNQ  183

Query  176  IIDMKGLMGDTSDNIPGVAGVGEKTAIKLLNQFDTVEGVYEHLDEISGKKLKEKLQNSKE  235
            +ID+K+LMGD SDNIPGV+ +GEKT++KLL++F+++EG+YEH+D +   K+KE+L N ++
Sbjct  184  FIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRD  243

Query  236  DALMSKELATINVDSPIEVKLEDTLMTHQDeqqekielfkklefkqllADIDQSASVEDA  295
            +A++SK LATIN  SPI + L+D +    D              +   + +    + E  
Sbjct  244  QAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKG-LASQMPQEPV  302

Query  296  IEKTFEIETSFDNIDFTSLKEAAIHFELDGGNYLRNNILKFSLFTGEKHIVINAD----D  351
               +++  T+     F++  E  + FE   +NY R+ I+ F+   GE +I  ++D     
Sbjct  303  AVISYQEVTNVSADLFSA--EDIFYFETLRDNYHREAIIGFAWGHGE-QIYASTDLSLLA  359

Query  352  INNYAELVSWLENPNTKKVVYDAKKTYVASHRLGIDIQNISFDIMLASYIIDPSRTISDV  411
             +++ ++   +++P +    YD K++ V   +LGI++   S+D  LA+Y++      +++
Sbjct  360  TDSFKQV---FQKPIA---TYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NEL  412

Query  412  QSVVSLYGQSFVKDDVSIYGKGKKFKVPEDDVLNPYVASITDAIYFAKPNMDKQLEEYNQ  471
             ++  ++ +  + +D ++YGKG K  VP+ DVL   +A     +  +K++M  +L   +Q
Sbjct  413  STIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQ  472

Query  472  VELLADLELPLAKILSEMEEIGIFTDVHDLEEMEKEIQEKLDVLIRNIHDAAGEDFNINS  531
            ++L  ++ELPLA++L+ ME  GI  +   L++M  + +  ++ L ++I D AG++FNINS
Sbjct  473  LDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINS  532

Query  532  PKQLGVVLFETLQLP--VIKKTKTGYSTAVDVLEQLQGEHPIIDYILEYRQLSKLQSTYV  589
            PKQLG +LFE +QLP  + KKTKTGYSTAVDVLE+L    PI+  IL+YRQ++KLQSTYV
Sbjct  533  PKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYV  592

Query  590  EGLQKVISDDQRIHTRFNQTLAQTGRLSSVDPNLQNIPVRLEEGRKIRKAFKPTSKDSVI  649
             GLQ  I  D +IHTR+ Q L+QTGRLSSVDPNLQNIP+RLE+GR IRKAF P+  D+V+
Sbjct  593  IGLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVL  652

Query  650  LSADYSQIELRVLAHITQDESMKEAFINGDDIHTATAMKVFGVE-ADQVDSLMRRQAKAV  708
            LS+DYSQIELRVLAHI+ DE +  AF +G DIHT+TAM+VFG++ A +V +  RR+AKAV
Sbjct  653  LSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAV  712

Query  709  NFGIVYGISDYGLSQSLGITRKKAKAFIDDYLASFPGVKQYMSDIVKDAKALGYVETLLH  768
            NFGIVYGISD+GLS++LGITRK++K++ID Y+  +PG+K YM ++V++AK  GYVETL+ 
Sbjct  713  NFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFK  772

Query  769  RRRYIPDITSRNFNLRGFAERTAMNTPIQGSAADIIKLAMVKFAQKMKETTYQAKLLLQV  828
            RRR +PDI SRNFN+R+FAERTA+N+PIQGSAADI+K+AM+++ + ++   ++AK+LLQV
Sbjct  773  RRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQV  832

Query  829  HDELIFEVPKsevdsfsefveeIMENALQLDVPLKVDSSYGATWYDAK  876
            HDE+++EVP+ E+ ++  +V + ME A++L VPL VD S G +WY+AK
Sbjct  833  HDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

358) SAAG_01594 in NC_022113


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  676 bits (2556),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 424/884 (48%), Positives = 633/884 (72%), Gaps = 17/884 (1%)

Query  2    NKLVLIDGNSLSFRAFYAL----PLLSNKAGIHTNAVYGFAMLLEKILKEEKPNHFLVAF  57
            NKL+LIDG+S++FRAF+AL      + N +G+HTNA+YGF ++L+ ++K  +P H LVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  58   DAGKTTFRHEKYSEYKGGRQKTPPELSEQFPYIRQLLDAYHIKRYELDNYEADDIIGTLS  117
            DAGKTTFR E Y++YK+GR KTP E+ EQF+YIR++L A  I  YEL++YEADDIIGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  118  KEADKAG--FQTIIITGDRDLTQLATDNVTIYYTKKGVTDVDHYTPDFIAEKYNGLTPNQ  175
            K A+++   F+  I++GD+DL QL+ +N  +  +KKGV++ +++TP ++ EK  GLTPNQ
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEK-MGLTPNQ  183

Query  176  IIDMKGLMGDTSDNIPGVAGVGEKTAIKLLNQFDTVEGVYEHLDEISGKKLKEKLQNSKE  235
            +ID+K+LMGD SDNIPGV+ +GEKT++KLL++F+++EG+YEH+D +   K+KE+L N ++
Sbjct  184  FIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRD  243

Query  236  DALMSKELATINVDSPIEVKLEDTLMTHQDeqqekielfkklefkqllADIDQSASGEDA  295
            +A++SK LATIN  SPI + L+D +    D              +   +   Q +    A
Sbjct  244  QAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEPVA  303

Query  296  IEKTFEIETSFDNVDFTSLKEATIHFELDGGNYLRNNILKFSLFTGEKHIVINADDIINY  355
            +  +++  T+     F++  E  + FE   +NY R+ I+ F+   GE+        ++  
Sbjct  304  V-ISYQEVTNVSADLFSA--EDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLAT  360

Query  356  AELVSWLENPNTKKVVYDAKKTYVASHRLGIDIQNISFDIMLASYIIDPSRTISDVQSVV  415
              +   +++P +    YD K++ V   +LGI++   S+D  LA+Y++      +++ ++ 
Sbjct  361  DSFKQVFQKPIA---TYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NELSTIA  416

Query  416  SLYGQSFVKDDVSIYGKGKKFKVPEDDVLNPYVASITDAIYFAKPNMDKQLEEYNQVELL  475
             ++ +  + +D ++YGKG K  VP+ DVL   +A     +  +K++M  +L   +Q++L 
Sbjct  417  RIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLY  476

Query  476  ADLELPLAKILSEMEEIGIYTDVHDLEEMEKEIQEKLDVLIRNIHDAAGEDFNINSPKQL  535
             ++ELPLA++L+ ME  GI  +   L++M  + +  ++ L ++I D AG++FNINSPKQL
Sbjct  477  QNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQL  536

Query  536  GVVLFETLQLP--VIKKTKTGYSTAVDVLEQLQGEHPIIDYILEYRQLSKLQSTYVEGLQ  593
            G +LFE +QLP  + KKTKTGYSTAVDVLE+L    PI+  IL+YRQ++KLQSTYV GLQ
Sbjct  537  GSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQ  596

Query  594  KVISDDQRIHTRFNQTLAQTGRLSSVDPNLQNIPVRLEEGRKIRKAFKPTSKDSVILSAD  653
              I  D +IHTR+ Q L+QTGRLSSVDPNLQNIP+RLE+GR IRKAF P+  D+V+LS+D
Sbjct  597  DYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSD  656

Query  654  YSQIELRVLAHITQDESMKEAFINGDDIHTATAMKVFGVE-ADQVDSLMRRQAKAVNFGI  712
            YSQIELRVLAHI+ DE +  AF +G DIHT+TAM+VFG++ A +V +  RR+AKAVNFGI
Sbjct  657  YSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGI  716

Query  713  VYGISDYGLSQSLGITRKKAKAFIDDYLASFPGVKQYMSDIVKDAKALGFVETLLHRRRY  772
            VYGISD+GLS++LGITRK++K++ID Y+  +PG+K YM ++V++AK  G+VETL+ RRR 
Sbjct  717  VYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRE  776

Query  773  IPDITSRNFNLRGFAERTAMNTPIQGSAADIIKLAMVKFAQKMKETTYQAKLLLQVHDEL  832
            +PDI SRNFN+R+FAERTA+N+PIQGSAADI+K+AM+++ + ++   ++AK+LLQVHDE+
Sbjct  777  LPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEI  836

Query  833  IFEVPKsevdsfsefveeIMENALQLDVPLKVDSSYGATWYDAK  876
            ++EVP+ E+ ++  +V + ME A++L VPL VD S G +WY+AK
Sbjct  837  VLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

359) polA in NC_017343


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  676 bits (2556),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 426/888 (48%), Positives = 638/888 (72%), Gaps = 25/888 (2%)

Query  2    NKLVLIDGNSLSFRAFYAL----PLLSNKAGIHTNAVYGFAMLLEKILKEEKPNHFLVAF  57
            NKL+LIDG+S++FRAF+AL      + N +G+HTNA+YGF ++L+ ++K  +P H LVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  58   DAGKTTFRHEKYSEYKGGRQKTPPELSEQFPYIRQLLDAYHIKRYELDNYEADDIIGTLS  117
            DAGKTTFR E Y++YK+GR KTP E+ EQF+YIR++L A  I  YEL++YEADDIIGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  118  KEADKAG--FQTIIITGDRDLTQLATDNVTIYYTKKGVTDVDHYTPDFIAEKYNGLTPNQ  175
            K A+++   F+  I++GD+DL QL+ +N  +  +KKGV++ +++TP ++ EK  GLTPNQ
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEK-MGLTPNQ  183

Query  176  IIDMKGLMGDTSDNIPGVAGVGEKTAIKLLNQFDTVEGVYEHLDEISGKKLKEKLQNSKE  235
            +ID+K+LMGD SDNIPGV+ +GEKT++KLL++F+++EG+YEH+D +   K+KE+L N ++
Sbjct  184  FIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRD  243

Query  236  DALMSKELATINVDSPIEVKLEDTLMTHQDeqqekielfkklefkqllSDIDQSASVEDA  295
            +A++SK LATIN  SPI + L+D +    D              +   + +    + E  
Sbjct  244  QAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKG-LASQMPQEPV  302

Query  296  IEKTFEIETSFDNIDFTSLKEAAIHFELDGGNYLRNNILKFSLFTGEKHIVINAD----D  351
               +++  T+     F++  E  + FE   +NY R+ I+ F+   GE +I  ++D     
Sbjct  303  AVISYQEVTNVSADLFSA--EDIFYFETLRDNYHREAIIGFAWGHGE-QIYASTDLSLLA  359

Query  352  INNYAELVSWLENPNTKKVVYDAKKTYVASHRLGIDIQNISFDIMLASYIIDPSRTISDV  411
             +++ ++   +++P +    YD K++ V   +LGI++   S+D  LA+Y++      +++
Sbjct  360  TDSFKQV---FQKPIA---TYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NEL  412

Query  412  QSVVSLYGQSFVKDDVSIYGKGKKFKVPEDDVLNPYVASITDAIYFAKPNMDKQLEEYNQ  471
             ++  ++ +  + +D ++YGKG K  VP+ DVL   +A     +  +K++M  +L   +Q
Sbjct  413  STIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQ  472

Query  472  VELLADLELPLAKILSEMEEIGIFTDVHDLEEMEKEIQEKLDVLIRNIHDAAGEDFNINS  531
            ++L  ++ELPLA++L+ ME  GI  +   L++M  + +  ++ L ++I D AG++FNINS
Sbjct  473  LDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINS  532

Query  532  PKQLGVVLFETLQLP--VIKKTKTGYSTAVDVLEQLQGEHPIIDYILEYRQLSKLQSTYV  589
            PKQLG +LFE +QLP  + KKTKTGYSTAVDVLE+L    PI+  IL+YRQ++KLQSTYV
Sbjct  533  PKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYV  592

Query  590  EGLQKVISDDQRIHTRFNQTLAQTGRLSSVDPNLQNIPVRLEEGRKIRKAFKPTSKDSVI  649
             GLQ  I  D +IHTR+ Q L+QTGRLSSVDPNLQNIP+RLE+GR IRKAF P+  D+V+
Sbjct  593  IGLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVL  652

Query  650  LSADYSQIELRVLAHITQDESMKEAFINGDDIHTATAMKVFGVE-ADQVDSLMRRQAKAV  708
            LS+DYSQIELRVLAHI+ DE +  AF +G DIHT+TAM+VFG++ A +V +  RR+AKAV
Sbjct  653  LSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAV  712

Query  709  NFGIVYGISDYGLSQSLGITRKKAKAFIDDYLASFPGVKQYMSDIVKDAKALGYVETLLH  768
            NFGIVYGISD+GLS++LGITRK++K++ID Y+  +PG+K YM ++V++AK  GYVETL+ 
Sbjct  713  NFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFK  772

Query  769  RRRYIPDITSRNFNLRGFAERTAMNTPIQGSAADIIKLAMVKFAQKMKETTYQAKLLLQV  828
            RRR +PDI SRNFN+R+FAERTA+N+PIQGSAADI+K+AM+++ + ++   ++AK+LLQV
Sbjct  773  RRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQV  832

Query  829  HDELIFEVPKsevdsfsefveeIMENALQLDVPLKVDSSYGATWYDAK  876
            HDE+++EVP+ E+ ++  +V + ME A++L VPL VD S G +WY+AK
Sbjct  833  HDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

360) polA in NC_013450


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  676 bits (2556),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 426/888 (48%), Positives = 638/888 (72%), Gaps = 25/888 (2%)

Query  2    NKLVLIDGNSLSFRAFYAL----PLLSNKAGIHTNAVYGFAMLLEKILKEEKPNHFLVAF  57
            NKL+LIDG+S++FRAF+AL      + N +G+HTNA+YGF ++L+ ++K  +P H LVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  58   DAGKTTFRHEKYSEYKGGRQKTPPELSEQFPYIRQLLDAYHIKRYELDNYEADDIIGTLS  117
            DAGKTTFR E Y++YK+GR KTP E+ EQF+YIR++L A  I  YEL++YEADDIIGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  118  KEADKAG--FQTIIITGDRDLTQLATDNVTIYYTKKGVTDVDHYTPDFIAEKYNGLTPNQ  175
            K A+++   F+  I++GD+DL QL+ +N  +  +KKGV++ +++TP ++ EK  GLTPNQ
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEK-MGLTPNQ  183

Query  176  IIDMKGLMGDTSDNIPGVAGVGEKTAIKLLNQFDTVEGVYEHLDEISGKKLKEKLQNSKE  235
            +ID+K+LMGD SDNIPGV+ +GEKT++KLL++F+++EG+YEH+D +   K+KE+L N ++
Sbjct  184  FIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRD  243

Query  236  DALMSKELATINVDSPIEVKLEDTLMTHQDeqqekielfkklefkqllSDIDQSASVEDA  295
            +A++SK LATIN  SPI + L+D +    D              +   + +    + E  
Sbjct  244  QAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKG-LASQMPQEPV  302

Query  296  IEKTFEIETSFDNIDFTSLKEAAIHFELDGGNYLRNNILKFSLFTGEKHIVINAD----D  351
               +++  T+     F++  E  + FE   +NY R+ I+ F+   GE +I  ++D     
Sbjct  303  AVISYQEVTNVSADLFSA--EDIFYFETLRDNYHREAIIGFAWGHGE-QIYASTDLSLLA  359

Query  352  INNYAELVSWLENPNTKKVVYDAKKTYVASHRLGIDIQNISFDIMLASYIIDPSRTISDV  411
             +++ ++   +++P +    YD K++ V   +LGI++   S+D  LA+Y++      +++
Sbjct  360  TDSFKQV---FQKPIA---TYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NEL  412

Query  412  QSVVSLYGQSFVKDDVSIYGKGKKFKVPEDDVLNPYVASITDAIYFAKPNMDKQLEEYNQ  471
             ++  ++ +  + +D ++YGKG K  VP+ DVL   +A     +  +K++M  +L   +Q
Sbjct  413  STIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQ  472

Query  472  VELLADLELPLAKILSEMEEIGIFTDVHDLEEMEKEIQEKLDVLIRNIHDAAGEDFNINS  531
            ++L  ++ELPLA++L+ ME  GI  +   L++M  + +  ++ L ++I D AG++FNINS
Sbjct  473  LDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINS  532

Query  532  PKQLGVVLFETLQLP--VIKKTKTGYSTAVDVLEQLQGEHPIIDYILEYRQLSKLQSTYV  589
            PKQLG +LFE +QLP  + KKTKTGYSTAVDVLE+L    PI+  IL+YRQ++KLQSTYV
Sbjct  533  PKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYV  592

Query  590  EGLQKVISDDQRIHTRFNQTLAQTGRLSSVDPNLQNIPVRLEEGRKIRKAFKPTSKDSVI  649
             GLQ  I  D +IHTR+ Q L+QTGRLSSVDPNLQNIP+RLE+GR IRKAF P+  D+V+
Sbjct  593  IGLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVL  652

Query  650  LSADYSQIELRVLAHITQDESMKEAFINGDDIHTATAMKVFGVE-ADQVDSLMRRQAKAV  708
            LS+DYSQIELRVLAHI+ DE +  AF +G DIHT+TAM+VFG++ A +V +  RR+AKAV
Sbjct  653  LSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAV  712

Query  709  NFGIVYGISDYGLSQSLGITRKKAKAFIDDYLASFPGVKQYMSDIVKDAKALGYVETLLH  768
            NFGIVYGISD+GLS++LGITRK++K++ID Y+  +PG+K YM ++V++AK  GYVETL+ 
Sbjct  713  NFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFK  772

Query  769  RRRYIPDITSRNFNLRGFAERTAMNTPIQGSAADIIKLAMVKFAQKMKETTYQAKLLLQV  828
            RRR +PDI SRNFN+R+FAERTA+N+PIQGSAADI+K+AM+++ + ++   ++AK+LLQV
Sbjct  773  RRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQV  832

Query  829  HDELIFEVPKsevdsfsefveeIMENALQLDVPLKVDSSYGATWYDAK  876
            HDE+++EVP+ E+ ++  +V + ME A++L VPL VD S G +WY+AK
Sbjct  833  HDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

361) SaurJH1_1781 in NC_009632


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  676 bits (2556),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 426/888 (48%), Positives = 638/888 (72%), Gaps = 25/888 (2%)

Query  2    NKLVLIDGNSLSFRAFYAL----PLLSNKAGIHTNAVYGFAMLLEKILKEEKPNHFLVAF  57
            NKL+LIDG+S++FRAF+AL      + N +G+HTNA+YGF ++L+ ++K  +P H LVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  58   DAGKTTFRHEKYSEYKGGRQKTPPELSEQFPYIRQLLDAYHIKRYELDNYEADDIIGTLS  117
            DAGKTTFR E Y++YK+GR KTP E+ EQF+YIR++L A  I  YEL++YEADDIIGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  118  KEADKAG--FQTIIITGDRDLTQLATDNVTIYYTKKGVTDVDHYTPDFIAEKYNGLTPNQ  175
            K A+++   F+  I++GD+DL QL+ +N  +  +KKGV++ +++TP ++ EK  GLTPNQ
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEK-MGLTPNQ  183

Query  176  IIDMKGLMGDTSDNIPGVAGVGEKTAIKLLNQFDTVEGVYEHLDEISGKKLKEKLQNSKE  235
            +ID+K+LMGD SDNIPGV+ +GEKT++KLL++F+++EG+YEH+D +   K+KE+L N ++
Sbjct  184  FIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRD  243

Query  236  DALMSKELATINVDSPIEVKLEDTLMTHQDeqqekielfkklefkqllSDIDQSASVEDA  295
            +A++SK LATIN  SPI + L+D +    D              +   + +    + E  
Sbjct  244  QAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKG-LASQMPQEPV  302

Query  296  IEKTFEIETSFDNIDFTSLKEAAIHFELDGGNYLRNNILKFSLFTGEKHIVINAD----D  351
               +++  T+     F++  E  + FE   +NY R+ I+ F+   GE +I  ++D     
Sbjct  303  AVISYQEVTNVSADLFSA--EDIFYFETLRDNYHREAIIGFAWGHGE-QIYASTDLSLLA  359

Query  352  INNYAELVSWLENPNTKKVVYDAKKTYVASHRLGIDIQNISFDIMLASYIIDPSRTISDV  411
             +++ ++   +++P +    YD K++ V   +LGI++   S+D  LA+Y++      +++
Sbjct  360  TDSFKQV---FQKPIA---TYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NEL  412

Query  412  QSVVSLYGQSFVKDDVSIYGKGKKFKVPEDDVLNPYVASITDAIYFAKPNMDKQLEEYNQ  471
             ++  ++ +  + +D ++YGKG K  VP+ DVL   +A     +  +K++M  +L   +Q
Sbjct  413  STIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQ  472

Query  472  VELLADLELPLAKILSEMEEIGIFTDVHDLEEMEKEIQEKLDVLIRNIHDAAGEDFNINS  531
            ++L  ++ELPLA++L+ ME  GI  +   L++M  + +  ++ L ++I D AG++FNINS
Sbjct  473  LDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINS  532

Query  532  PKQLGVVLFETLQLP--VIKKTKTGYSTAVDVLEQLQGEHPIIDYILEYRQLSKLQSTYV  589
            PKQLG +LFE +QLP  + KKTKTGYSTAVDVLE+L    PI+  IL+YRQ++KLQSTYV
Sbjct  533  PKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYV  592

Query  590  EGLQKVISDDQRIHTRFNQTLAQTGRLSSVDPNLQNIPVRLEEGRKIRKAFKPTSKDSVI  649
             GLQ  I  D +IHTR+ Q L+QTGRLSSVDPNLQNIP+RLE+GR IRKAF P+  D+V+
Sbjct  593  IGLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVL  652

Query  650  LSADYSQIELRVLAHITQDESMKEAFINGDDIHTATAMKVFGVE-ADQVDSLMRRQAKAV  708
            LS+DYSQIELRVLAHI+ DE +  AF +G DIHT+TAM+VFG++ A +V +  RR+AKAV
Sbjct  653  LSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAV  712

Query  709  NFGIVYGISDYGLSQSLGITRKKAKAFIDDYLASFPGVKQYMSDIVKDAKALGYVETLLH  768
            NFGIVYGISD+GLS++LGITRK++K++ID Y+  +PG+K YM ++V++AK  GYVETL+ 
Sbjct  713  NFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFK  772

Query  769  RRRYIPDITSRNFNLRGFAERTAMNTPIQGSAADIIKLAMVKFAQKMKETTYQAKLLLQV  828
            RRR +PDI SRNFN+R+FAERTA+N+PIQGSAADI+K+AM+++ + ++   ++AK+LLQV
Sbjct  773  RRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQV  832

Query  829  HDELIFEVPKsevdsfsefveeIMENALQLDVPLKVDSSYGATWYDAK  876
            HDE+++EVP+ E+ ++  +V + ME A++L VPL VD S G +WY+AK
Sbjct  833  HDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

362) SaurJH9_1747 in NC_009487


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  676 bits (2556),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 426/888 (48%), Positives = 638/888 (72%), Gaps = 25/888 (2%)

Query  2    NKLVLIDGNSLSFRAFYAL----PLLSNKAGIHTNAVYGFAMLLEKILKEEKPNHFLVAF  57
            NKL+LIDG+S++FRAF+AL      + N +G+HTNA+YGF ++L+ ++K  +P H LVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  58   DAGKTTFRHEKYSEYKGGRQKTPPELSEQFPYIRQLLDAYHIKRYELDNYEADDIIGTLS  117
            DAGKTTFR E Y++YK+GR KTP E+ EQF+YIR++L A  I  YEL++YEADDIIGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  118  KEADKAG--FQTIIITGDRDLTQLATDNVTIYYTKKGVTDVDHYTPDFIAEKYNGLTPNQ  175
            K A+++   F+  I++GD+DL QL+ +N  +  +KKGV++ +++TP ++ EK  GLTPNQ
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEK-MGLTPNQ  183

Query  176  IIDMKGLMGDTSDNIPGVAGVGEKTAIKLLNQFDTVEGVYEHLDEISGKKLKEKLQNSKE  235
            +ID+K+LMGD SDNIPGV+ +GEKT++KLL++F+++EG+YEH+D +   K+KE+L N ++
Sbjct  184  FIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRD  243

Query  236  DALMSKELATINVDSPIEVKLEDTLMTHQDeqqekielfkklefkqllSDIDQSASVEDA  295
            +A++SK LATIN  SPI + L+D +    D              +   + +    + E  
Sbjct  244  QAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKG-LASQMPQEPV  302

Query  296  IEKTFEIETSFDNIDFTSLKEAAIHFELDGGNYLRNNILKFSLFTGEKHIVINAD----D  351
               +++  T+     F++  E  + FE   +NY R+ I+ F+   GE +I  ++D     
Sbjct  303  AVISYQEVTNVSADLFSA--EDIFYFETLRDNYHREAIIGFAWGHGE-QIYASTDLSLLA  359

Query  352  INNYAELVSWLENPNTKKVVYDAKKTYVASHRLGIDIQNISFDIMLASYIIDPSRTISDV  411
             +++ ++   +++P +    YD K++ V   +LGI++   S+D  LA+Y++      +++
Sbjct  360  TDSFKQV---FQKPIA---TYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NEL  412

Query  412  QSVVSLYGQSFVKDDVSIYGKGKKFKVPEDDVLNPYVASITDAIYFAKPNMDKQLEEYNQ  471
             ++  ++ +  + +D ++YGKG K  VP+ DVL   +A     +  +K++M  +L   +Q
Sbjct  413  STIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQ  472

Query  472  VELLADLELPLAKILSEMEEIGIFTDVHDLEEMEKEIQEKLDVLIRNIHDAAGEDFNINS  531
            ++L  ++ELPLA++L+ ME  GI  +   L++M  + +  ++ L ++I D AG++FNINS
Sbjct  473  LDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINS  532

Query  532  PKQLGVVLFETLQLP--VIKKTKTGYSTAVDVLEQLQGEHPIIDYILEYRQLSKLQSTYV  589
            PKQLG +LFE +QLP  + KKTKTGYSTAVDVLE+L    PI+  IL+YRQ++KLQSTYV
Sbjct  533  PKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYV  592

Query  590  EGLQKVISDDQRIHTRFNQTLAQTGRLSSVDPNLQNIPVRLEEGRKIRKAFKPTSKDSVI  649
             GLQ  I  D +IHTR+ Q L+QTGRLSSVDPNLQNIP+RLE+GR IRKAF P+  D+V+
Sbjct  593  IGLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVL  652

Query  650  LSADYSQIELRVLAHITQDESMKEAFINGDDIHTATAMKVFGVE-ADQVDSLMRRQAKAV  708
            LS+DYSQIELRVLAHI+ DE +  AF +G DIHT+TAM+VFG++ A +V +  RR+AKAV
Sbjct  653  LSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAV  712

Query  709  NFGIVYGISDYGLSQSLGITRKKAKAFIDDYLASFPGVKQYMSDIVKDAKALGYVETLLH  768
            NFGIVYGISD+GLS++LGITRK++K++ID Y+  +PG+K YM ++V++AK  GYVETL+ 
Sbjct  713  NFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFK  772

Query  769  RRRYIPDITSRNFNLRGFAERTAMNTPIQGSAADIIKLAMVKFAQKMKETTYQAKLLLQV  828
            RRR +PDI SRNFN+R+FAERTA+N+PIQGSAADI+K+AM+++ + ++   ++AK+LLQV
Sbjct  773  RRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQV  832

Query  829  HDELIFEVPKsevdsfsefveeIMENALQLDVPLKVDSSYGATWYDAK  876
            HDE+++EVP+ E+ ++  +V + ME A++L VPL VD S G +WY+AK
Sbjct  833  HDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

363) polA in NC_009782


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  676 bits (2556),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 426/888 (48%), Positives = 638/888 (72%), Gaps = 25/888 (2%)

Query  2    NKLVLIDGNSLSFRAFYAL----PLLSNKAGIHTNAVYGFAMLLEKILKEEKPNHFLVAF  57
            NKL+LIDG+S++FRAF+AL      + N +G+HTNA+YGF ++L+ ++K  +P H LVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  58   DAGKTTFRHEKYSEYKGGRQKTPPELSEQFPYIRQLLDAYHIKRYELDNYEADDIIGTLS  117
            DAGKTTFR E Y++YK+GR KTP E+ EQF+YIR++L A  I  YEL++YEADDIIGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  118  KEADKAG--FQTIIITGDRDLTQLATDNVTIYYTKKGVTDVDHYTPDFIAEKYNGLTPNQ  175
            K A+++   F+  I++GD+DL QL+ +N  +  +KKGV++ +++TP ++ EK  GLTPNQ
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEK-MGLTPNQ  183

Query  176  IIDMKGLMGDTSDNIPGVAGVGEKTAIKLLNQFDTVEGVYEHLDEISGKKLKEKLQNSKE  235
            +ID+K+LMGD SDNIPGV+ +GEKT++KLL++F+++EG+YEH+D +   K+KE+L N ++
Sbjct  184  FIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRD  243

Query  236  DALMSKELATINVDSPIEVKLEDTLMTHQDeqqekielfkklefkqllSDIDQSASVEDA  295
            +A++SK LATIN  SPI + L+D +    D              +   + +    + E  
Sbjct  244  QAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKG-LASQMPQEPV  302

Query  296  IEKTFEIETSFDNIDFTSLKEAAIHFELDGGNYLRNNILKFSLFTGEKHIVINAD----D  351
               +++  T+     F++  E  + FE   +NY R+ I+ F+   GE +I  ++D     
Sbjct  303  AVISYQEVTNVSADLFSA--EDIFYFETLRDNYHREAIIGFAWGHGE-QIYASTDLSLLA  359

Query  352  INNYAELVSWLENPNTKKVVYDAKKTYVASHRLGIDIQNISFDIMLASYIIDPSRTISDV  411
             +++ ++   +++P +    YD K++ V   +LGI++   S+D  LA+Y++      +++
Sbjct  360  TDSFKQV---FQKPIA---TYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NEL  412

Query  412  QSVVSLYGQSFVKDDVSIYGKGKKFKVPEDDVLNPYVASITDAIYFAKPNMDKQLEEYNQ  471
             ++  ++ +  + +D ++YGKG K  VP+ DVL   +A     +  +K++M  +L   +Q
Sbjct  413  STIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQ  472

Query  472  VELLADLELPLAKILSEMEEIGIFTDVHDLEEMEKEIQEKLDVLIRNIHDAAGEDFNINS  531
            ++L  ++ELPLA++L+ ME  GI  +   L++M  + +  ++ L ++I D AG++FNINS
Sbjct  473  LDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINS  532

Query  532  PKQLGVVLFETLQLP--VIKKTKTGYSTAVDVLEQLQGEHPIIDYILEYRQLSKLQSTYV  589
            PKQLG +LFE +QLP  + KKTKTGYSTAVDVLE+L    PI+  IL+YRQ++KLQSTYV
Sbjct  533  PKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYV  592

Query  590  EGLQKVISDDQRIHTRFNQTLAQTGRLSSVDPNLQNIPVRLEEGRKIRKAFKPTSKDSVI  649
             GLQ  I  D +IHTR+ Q L+QTGRLSSVDPNLQNIP+RLE+GR IRKAF P+  D+V+
Sbjct  593  IGLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVL  652

Query  650  LSADYSQIELRVLAHITQDESMKEAFINGDDIHTATAMKVFGVE-ADQVDSLMRRQAKAV  708
            LS+DYSQIELRVLAHI+ DE +  AF +G DIHT+TAM+VFG++ A +V +  RR+AKAV
Sbjct  653  LSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAV  712

Query  709  NFGIVYGISDYGLSQSLGITRKKAKAFIDDYLASFPGVKQYMSDIVKDAKALGYVETLLH  768
            NFGIVYGISD+GLS++LGITRK++K++ID Y+  +PG+K YM ++V++AK  GYVETL+ 
Sbjct  713  NFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFK  772

Query  769  RRRYIPDITSRNFNLRGFAERTAMNTPIQGSAADIIKLAMVKFAQKMKETTYQAKLLLQV  828
            RRR +PDI SRNFN+R+FAERTA+N+PIQGSAADI+K+AM+++ + ++   ++AK+LLQV
Sbjct  773  RRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQV  832

Query  829  HDELIFEVPKsevdsfsefveeIMENALQLDVPLKVDSSYGATWYDAK  876
            HDE+++EVP+ E+ ++  +V + ME A++L VPL VD S G +WY+AK
Sbjct  833  HDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

364) polA in NC_002758


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  676 bits (2556),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 426/888 (48%), Positives = 638/888 (72%), Gaps = 25/888 (2%)

Query  2    NKLVLIDGNSLSFRAFYAL----PLLSNKAGIHTNAVYGFAMLLEKILKEEKPNHFLVAF  57
            NKL+LIDG+S++FRAF+AL      + N +G+HTNA+YGF ++L+ ++K  +P H LVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  58   DAGKTTFRHEKYSEYKGGRQKTPPELSEQFPYIRQLLDAYHIKRYELDNYEADDIIGTLS  117
            DAGKTTFR E Y++YK+GR KTP E+ EQF+YIR++L A  I  YEL++YEADDIIGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  118  KEADKAG--FQTIIITGDRDLTQLATDNVTIYYTKKGVTDVDHYTPDFIAEKYNGLTPNQ  175
            K A+++   F+  I++GD+DL QL+ +N  +  +KKGV++ +++TP ++ EK  GLTPNQ
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEK-MGLTPNQ  183

Query  176  IIDMKGLMGDTSDNIPGVAGVGEKTAIKLLNQFDTVEGVYEHLDEISGKKLKEKLQNSKE  235
            +ID+K+LMGD SDNIPGV+ +GEKT++KLL++F+++EG+YEH+D +   K+KE+L N ++
Sbjct  184  FIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRD  243

Query  236  DALMSKELATINVDSPIEVKLEDTLMTHQDeqqekielfkklefkqllSDIDQSASVEDA  295
            +A++SK LATIN  SPI + L+D +    D              +   + +    + E  
Sbjct  244  QAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKG-LASQMPQEPV  302

Query  296  IEKTFEIETSFDNIDFTSLKEAAIHFELDGGNYLRNNILKFSLFTGEKHIVINAD----D  351
               +++  T+     F++  E  + FE   +NY R+ I+ F+   GE +I  ++D     
Sbjct  303  AVISYQEVTNVSADLFSA--EDIFYFETLRDNYHREAIIGFAWGHGE-QIYASTDLSLLA  359

Query  352  INNYAELVSWLENPNTKKVVYDAKKTYVASHRLGIDIQNISFDIMLASYIIDPSRTISDV  411
             +++ ++   +++P +    YD K++ V   +LGI++   S+D  LA+Y++      +++
Sbjct  360  TDSFKQV---FQKPIA---TYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NEL  412

Query  412  QSVVSLYGQSFVKDDVSIYGKGKKFKVPEDDVLNPYVASITDAIYFAKPNMDKQLEEYNQ  471
             ++  ++ +  + +D ++YGKG K  VP+ DVL   +A     +  +K++M  +L   +Q
Sbjct  413  STIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQ  472

Query  472  VELLADLELPLAKILSEMEEIGIFTDVHDLEEMEKEIQEKLDVLIRNIHDAAGEDFNINS  531
            ++L  ++ELPLA++L+ ME  GI  +   L++M  + +  ++ L ++I D AG++FNINS
Sbjct  473  LDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINS  532

Query  532  PKQLGVVLFETLQLP--VIKKTKTGYSTAVDVLEQLQGEHPIIDYILEYRQLSKLQSTYV  589
            PKQLG +LFE +QLP  + KKTKTGYSTAVDVLE+L    PI+  IL+YRQ++KLQSTYV
Sbjct  533  PKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYV  592

Query  590  EGLQKVISDDQRIHTRFNQTLAQTGRLSSVDPNLQNIPVRLEEGRKIRKAFKPTSKDSVI  649
             GLQ  I  D +IHTR+ Q L+QTGRLSSVDPNLQNIP+RLE+GR IRKAF P+  D+V+
Sbjct  593  IGLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVL  652

Query  650  LSADYSQIELRVLAHITQDESMKEAFINGDDIHTATAMKVFGVE-ADQVDSLMRRQAKAV  708
            LS+DYSQIELRVLAHI+ DE +  AF +G DIHT+TAM+VFG++ A +V +  RR+AKAV
Sbjct  653  LSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAV  712

Query  709  NFGIVYGISDYGLSQSLGITRKKAKAFIDDYLASFPGVKQYMSDIVKDAKALGYVETLLH  768
            NFGIVYGISD+GLS++LGITRK++K++ID Y+  +PG+K YM ++V++AK  GYVETL+ 
Sbjct  713  NFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFK  772

Query  769  RRRYIPDITSRNFNLRGFAERTAMNTPIQGSAADIIKLAMVKFAQKMKETTYQAKLLLQV  828
            RRR +PDI SRNFN+R+FAERTA+N+PIQGSAADI+K+AM+++ + ++   ++AK+LLQV
Sbjct  773  RRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQV  832

Query  829  HDELIFEVPKsevdsfsefveeIMENALQLDVPLKVDSSYGATWYDAK  876
            HDE+++EVP+ E+ ++  +V + ME A++L VPL VD S G +WY+AK
Sbjct  833  HDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

365) polA in NC_002745


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  676 bits (2556),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 426/888 (48%), Positives = 638/888 (72%), Gaps = 25/888 (2%)

Query  2    NKLVLIDGNSLSFRAFYAL----PLLSNKAGIHTNAVYGFAMLLEKILKEEKPNHFLVAF  57
            NKL+LIDG+S++FRAF+AL      + N +G+HTNA+YGF ++L+ ++K  +P H LVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  58   DAGKTTFRHEKYSEYKGGRQKTPPELSEQFPYIRQLLDAYHIKRYELDNYEADDIIGTLS  117
            DAGKTTFR E Y++YK+GR KTP E+ EQF+YIR++L A  I  YEL++YEADDIIGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  118  KEADKAG--FQTIIITGDRDLTQLATDNVTIYYTKKGVTDVDHYTPDFIAEKYNGLTPNQ  175
            K A+++   F+  I++GD+DL QL+ +N  +  +KKGV++ +++TP ++ EK  GLTPNQ
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEK-MGLTPNQ  183

Query  176  IIDMKGLMGDTSDNIPGVAGVGEKTAIKLLNQFDTVEGVYEHLDEISGKKLKEKLQNSKE  235
            +ID+K+LMGD SDNIPGV+ +GEKT++KLL++F+++EG+YEH+D +   K+KE+L N ++
Sbjct  184  FIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRD  243

Query  236  DALMSKELATINVDSPIEVKLEDTLMTHQDeqqekielfkklefkqllSDIDQSASVEDA  295
            +A++SK LATIN  SPI + L+D +    D              +   + +    + E  
Sbjct  244  QAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKG-LASQMPQEPV  302

Query  296  IEKTFEIETSFDNIDFTSLKEAAIHFELDGGNYLRNNILKFSLFTGEKHIVINAD----D  351
               +++  T+     F++  E  + FE   +NY R+ I+ F+   GE +I  ++D     
Sbjct  303  AVISYQEVTNVSADLFSA--EDIFYFETLRDNYHREAIIGFAWGHGE-QIYASTDLSLLA  359

Query  352  INNYAELVSWLENPNTKKVVYDAKKTYVASHRLGIDIQNISFDIMLASYIIDPSRTISDV  411
             +++ ++   +++P +    YD K++ V   +LGI++   S+D  LA+Y++      +++
Sbjct  360  TDSFKQV---FQKPIA---TYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NEL  412

Query  412  QSVVSLYGQSFVKDDVSIYGKGKKFKVPEDDVLNPYVASITDAIYFAKPNMDKQLEEYNQ  471
             ++  ++ +  + +D ++YGKG K  VP+ DVL   +A     +  +K++M  +L   +Q
Sbjct  413  STIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQ  472

Query  472  VELLADLELPLAKILSEMEEIGIFTDVHDLEEMEKEIQEKLDVLIRNIHDAAGEDFNINS  531
            ++L  ++ELPLA++L+ ME  GI  +   L++M  + +  ++ L ++I D AG++FNINS
Sbjct  473  LDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINS  532

Query  532  PKQLGVVLFETLQLP--VIKKTKTGYSTAVDVLEQLQGEHPIIDYILEYRQLSKLQSTYV  589
            PKQLG +LFE +QLP  + KKTKTGYSTAVDVLE+L    PI+  IL+YRQ++KLQSTYV
Sbjct  533  PKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYV  592

Query  590  EGLQKVISDDQRIHTRFNQTLAQTGRLSSVDPNLQNIPVRLEEGRKIRKAFKPTSKDSVI  649
             GLQ  I  D +IHTR+ Q L+QTGRLSSVDPNLQNIP+RLE+GR IRKAF P+  D+V+
Sbjct  593  IGLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVL  652

Query  650  LSADYSQIELRVLAHITQDESMKEAFINGDDIHTATAMKVFGVE-ADQVDSLMRRQAKAV  708
            LS+DYSQIELRVLAHI+ DE +  AF +G DIHT+TAM+VFG++ A +V +  RR+AKAV
Sbjct  653  LSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAV  712

Query  709  NFGIVYGISDYGLSQSLGITRKKAKAFIDDYLASFPGVKQYMSDIVKDAKALGYVETLLH  768
            NFGIVYGISD+GLS++LGITRK++K++ID Y+  +PG+K YM ++V++AK  GYVETL+ 
Sbjct  713  NFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFK  772

Query  769  RRRYIPDITSRNFNLRGFAERTAMNTPIQGSAADIIKLAMVKFAQKMKETTYQAKLLLQV  828
            RRR +PDI SRNFN+R+FAERTA+N+PIQGSAADI+K+AM+++ + ++   ++AK+LLQV
Sbjct  773  RRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQV  832

Query  829  HDELIFEVPKsevdsfsefveeIMENALQLDVPLKVDSSYGATWYDAK  876
            HDE+++EVP+ E+ ++  +V + ME A++L VPL VD S G +WY+AK
Sbjct  833  HDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

366) polA in NC_020529


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  676 bits (2556),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 426/888 (48%), Positives = 638/888 (72%), Gaps = 25/888 (2%)

Query  2    NKLVLIDGNSLSFRAFYAL----PLLSNKAGIHTNAVYGFAMLLEKILKEEKPNHFLVAF  57
            NKL+LIDG+S++FRAF+AL      + N +G+HTNA+YGF ++L+ ++K  +P H LVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  58   DAGKTTFRHEKYSEYKGGRQKTPPELSEQFPYIRQLLDAYHIKRYELDNYEADDIIGTLS  117
            DAGKTTFR E Y++YK+GR KTP E+ EQF+YIR++L A  I  YEL++YEADDIIGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  118  KEADKAG--FQTIIITGDRDLTQLATDNVTIYYTKKGVTDVDHYTPDFIAEKYNGLTPNQ  175
            K A+++   F+  I++GD+DL QL+ +N  +  +KKGV++ +++TP ++ EK  GLTPNQ
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEK-MGLTPNQ  183

Query  176  IIDMKGLMGDTSDNIPGVAGVGEKTAIKLLNQFDTVEGVYEHLDEISGKKLKEKLQNSKE  235
            +ID+K+LMGD SDNIPGV+ +GEKT++KLL++F+++EG+YEH+D +   K+KE+L N ++
Sbjct  184  FIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRD  243

Query  236  DALMSKELATINVDSPIEVKLEDTLMTHQDeqqekielfkklefkqllSDIDQSASVEDA  295
            +A++SK LATIN  SPI + L+D +    D              +   + +    + E  
Sbjct  244  QAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKG-LASQMPQEPV  302

Query  296  IEKTFEIETSFDNIDFTSLKEAAIHFELDGGNYLRNNILKFSLFTGEKHIVINAD----D  351
               +++  T+     F++  E  + FE   +NY R+ I+ F+   GE +I  ++D     
Sbjct  303  AVISYQEVTNVSADLFSA--EDIFYFETLRDNYHREAIIGFAWGHGE-QIYASTDLSLLA  359

Query  352  INNYAELVSWLENPNTKKVVYDAKKTYVASHRLGIDIQNISFDIMLASYIIDPSRTISDV  411
             +++ ++   +++P +    YD K++ V   +LGI++   S+D  LA+Y++      +++
Sbjct  360  TDSFKQV---FQKPIA---TYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NEL  412

Query  412  QSVVSLYGQSFVKDDVSIYGKGKKFKVPEDDVLNPYVASITDAIYFAKPNMDKQLEEYNQ  471
             ++  ++ +  + +D ++YGKG K  VP+ DVL   +A     +  +K++M  +L   +Q
Sbjct  413  STIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQ  472

Query  472  VELLADLELPLAKILSEMEEIGIFTDVHDLEEMEKEIQEKLDVLIRNIHDAAGEDFNINS  531
            ++L  ++ELPLA++L+ ME  GI  +   L++M  + +  ++ L ++I D AG++FNINS
Sbjct  473  LDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINS  532

Query  532  PKQLGVVLFETLQLP--VIKKTKTGYSTAVDVLEQLQGEHPIIDYILEYRQLSKLQSTYV  589
            PKQLG +LFE +QLP  + KKTKTGYSTAVDVLE+L    PI+  IL+YRQ++KLQSTYV
Sbjct  533  PKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYV  592

Query  590  EGLQKVISDDQRIHTRFNQTLAQTGRLSSVDPNLQNIPVRLEEGRKIRKAFKPTSKDSVI  649
             GLQ  I  D +IHTR+ Q L+QTGRLSSVDPNLQNIP+RLE+GR IRKAF P+  D+V+
Sbjct  593  IGLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVL  652

Query  650  LSADYSQIELRVLAHITQDESMKEAFINGDDIHTATAMKVFGVE-ADQVDSLMRRQAKAV  708
            LS+DYSQIELRVLAHI+ DE +  AF +G DIHT+TAM+VFG++ A +V +  RR+AKAV
Sbjct  653  LSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAV  712

Query  709  NFGIVYGISDYGLSQSLGITRKKAKAFIDDYLASFPGVKQYMSDIVKDAKALGYVETLLH  768
            NFGIVYGISD+GLS++LGITRK++K++ID Y+  +PG+K YM ++V++AK  GYVETL+ 
Sbjct  713  NFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFK  772

Query  769  RRRYIPDITSRNFNLRGFAERTAMNTPIQGSAADIIKLAMVKFAQKMKETTYQAKLLLQV  828
            RRR +PDI SRNFN+R+FAERTA+N+PIQGSAADI+K+AM+++ + ++   ++AK+LLQV
Sbjct  773  RRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQV  832

Query  829  HDELIFEVPKsevdsfsefveeIMENALQLDVPLKVDSSYGATWYDAK  876
            HDE+++EVP+ E+ ++  +V + ME A++L VPL VD S G +WY+AK
Sbjct  833  HDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

367) polA in NC_020564


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  676 bits (2556),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 426/888 (48%), Positives = 638/888 (72%), Gaps = 25/888 (2%)

Query  2    NKLVLIDGNSLSFRAFYAL----PLLSNKAGIHTNAVYGFAMLLEKILKEEKPNHFLVAF  57
            NKL+LIDG+S++FRAF+AL      + N +G+HTNA+YGF ++L+ ++K  +P H LVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  58   DAGKTTFRHEKYSEYKGGRQKTPPELSEQFPYIRQLLDAYHIKRYELDNYEADDIIGTLS  117
            DAGKTTFR E Y++YK+GR KTP E+ EQF+YIR++L A  I  YEL++YEADDIIGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  118  KEADKAG--FQTIIITGDRDLTQLATDNVTIYYTKKGVTDVDHYTPDFIAEKYNGLTPNQ  175
            K A+++   F+  I++GD+DL QL+ +N  +  +KKGV++ +++TP ++ EK  GLTPNQ
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEK-MGLTPNQ  183

Query  176  IIDMKGLMGDTSDNIPGVAGVGEKTAIKLLNQFDTVEGVYEHLDEISGKKLKEKLQNSKE  235
            +ID+K+LMGD SDNIPGV+ +GEKT++KLL++F+++EG+YEH+D +   K+KE+L N ++
Sbjct  184  FIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRD  243

Query  236  DALMSKELATINVDSPIEVKLEDTLMTHQDeqqekielfkklefkqllSDIDQSASVEDA  295
            +A++SK LATIN  SPI + L+D +    D              +   + +    + E  
Sbjct  244  QAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKG-LASQMPQEPV  302

Query  296  IEKTFEIETSFDNIDFTSLKEAAIHFELDGGNYLRNNILKFSLFTGEKHIVINAD----D  351
               +++  T+     F++  E  + FE   +NY R+ I+ F+   GE +I  ++D     
Sbjct  303  AVISYQEVTNVSADLFSA--EDIFYFETLRDNYHREAIIGFAWGHGE-QIYASTDLSLLA  359

Query  352  INNYAELVSWLENPNTKKVVYDAKKTYVASHRLGIDIQNISFDIMLASYIIDPSRTISDV  411
             +++ ++   +++P +    YD K++ V   +LGI++   S+D  LA+Y++      +++
Sbjct  360  TDSFKQV---FQKPIA---TYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NEL  412

Query  412  QSVVSLYGQSFVKDDVSIYGKGKKFKVPEDDVLNPYVASITDAIYFAKPNMDKQLEEYNQ  471
             ++  ++ +  + +D ++YGKG K  VP+ DVL   +A     +  +K++M  +L   +Q
Sbjct  413  STIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQ  472

Query  472  VELLADLELPLAKILSEMEEIGIFTDVHDLEEMEKEIQEKLDVLIRNIHDAAGEDFNINS  531
            ++L  ++ELPLA++L+ ME  GI  +   L++M  + +  ++ L ++I D AG++FNINS
Sbjct  473  LDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINS  532

Query  532  PKQLGVVLFETLQLP--VIKKTKTGYSTAVDVLEQLQGEHPIIDYILEYRQLSKLQSTYV  589
            PKQLG +LFE +QLP  + KKTKTGYSTAVDVLE+L    PI+  IL+YRQ++KLQSTYV
Sbjct  533  PKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYV  592

Query  590  EGLQKVISDDQRIHTRFNQTLAQTGRLSSVDPNLQNIPVRLEEGRKIRKAFKPTSKDSVI  649
             GLQ  I  D +IHTR+ Q L+QTGRLSSVDPNLQNIP+RLE+GR IRKAF P+  D+V+
Sbjct  593  IGLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVL  652

Query  650  LSADYSQIELRVLAHITQDESMKEAFINGDDIHTATAMKVFGVE-ADQVDSLMRRQAKAV  708
            LS+DYSQIELRVLAHI+ DE +  AF +G DIHT+TAM+VFG++ A +V +  RR+AKAV
Sbjct  653  LSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAV  712

Query  709  NFGIVYGISDYGLSQSLGITRKKAKAFIDDYLASFPGVKQYMSDIVKDAKALGYVETLLH  768
            NFGIVYGISD+GLS++LGITRK++K++ID Y+  +PG+K YM ++V++AK  GYVETL+ 
Sbjct  713  NFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFK  772

Query  769  RRRYIPDITSRNFNLRGFAERTAMNTPIQGSAADIIKLAMVKFAQKMKETTYQAKLLLQV  828
            RRR +PDI SRNFN+R+FAERTA+N+PIQGSAADI+K+AM+++ + ++   ++AK+LLQV
Sbjct  773  RRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQV  832

Query  829  HDELIFEVPKsevdsfsefveeIMENALQLDVPLKVDSSYGATWYDAK  876
            HDE+++EVP+ E+ ++  +V + ME A++L VPL VD S G +WY+AK
Sbjct  833  HDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

368) polA in NC_020532


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  676 bits (2556),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 426/888 (48%), Positives = 638/888 (72%), Gaps = 25/888 (2%)

Query  2    NKLVLIDGNSLSFRAFYAL----PLLSNKAGIHTNAVYGFAMLLEKILKEEKPNHFLVAF  57
            NKL+LIDG+S++FRAF+AL      + N +G+HTNA+YGF ++L+ ++K  +P H LVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  58   DAGKTTFRHEKYSEYKGGRQKTPPELSEQFPYIRQLLDAYHIKRYELDNYEADDIIGTLS  117
            DAGKTTFR E Y++YK+GR KTP E+ EQF+YIR++L A  I  YEL++YEADDIIGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  118  KEADKAG--FQTIIITGDRDLTQLATDNVTIYYTKKGVTDVDHYTPDFIAEKYNGLTPNQ  175
            K A+++   F+  I++GD+DL QL+ +N  +  +KKGV++ +++TP ++ EK  GLTPNQ
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEK-MGLTPNQ  183

Query  176  IIDMKGLMGDTSDNIPGVAGVGEKTAIKLLNQFDTVEGVYEHLDEISGKKLKEKLQNSKE  235
            +ID+K+LMGD SDNIPGV+ +GEKT++KLL++F+++EG+YEH+D +   K+KE+L N ++
Sbjct  184  FIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRD  243

Query  236  DALMSKELATINVDSPIEVKLEDTLMTHQDeqqekielfkklefkqllSDIDQSASVEDA  295
            +A++SK LATIN  SPI + L+D +    D              +   + +    + E  
Sbjct  244  QAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKG-LASQMPQEPV  302

Query  296  IEKTFEIETSFDNIDFTSLKEAAIHFELDGGNYLRNNILKFSLFTGEKHIVINAD----D  351
               +++  T+     F++  E  + FE   +NY R+ I+ F+   GE +I  ++D     
Sbjct  303  AVISYQEVTNVSADLFSA--EDIFYFETLRDNYHREAIIGFAWGHGE-QIYASTDLSLLA  359

Query  352  INNYAELVSWLENPNTKKVVYDAKKTYVASHRLGIDIQNISFDIMLASYIIDPSRTISDV  411
             +++ ++   +++P +    YD K++ V   +LGI++   S+D  LA+Y++      +++
Sbjct  360  TDSFKQV---FQKPIA---TYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NEL  412

Query  412  QSVVSLYGQSFVKDDVSIYGKGKKFKVPEDDVLNPYVASITDAIYFAKPNMDKQLEEYNQ  471
             ++  ++ +  + +D ++YGKG K  VP+ DVL   +A     +  +K++M  +L   +Q
Sbjct  413  STIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQ  472

Query  472  VELLADLELPLAKILSEMEEIGIFTDVHDLEEMEKEIQEKLDVLIRNIHDAAGEDFNINS  531
            ++L  ++ELPLA++L+ ME  GI  +   L++M  + +  ++ L ++I D AG++FNINS
Sbjct  473  LDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINS  532

Query  532  PKQLGVVLFETLQLP--VIKKTKTGYSTAVDVLEQLQGEHPIIDYILEYRQLSKLQSTYV  589
            PKQLG +LFE +QLP  + KKTKTGYSTAVDVLE+L    PI+  IL+YRQ++KLQSTYV
Sbjct  533  PKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYV  592

Query  590  EGLQKVISDDQRIHTRFNQTLAQTGRLSSVDPNLQNIPVRLEEGRKIRKAFKPTSKDSVI  649
             GLQ  I  D +IHTR+ Q L+QTGRLSSVDPNLQNIP+RLE+GR IRKAF P+  D+V+
Sbjct  593  IGLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVL  652

Query  650  LSADYSQIELRVLAHITQDESMKEAFINGDDIHTATAMKVFGVE-ADQVDSLMRRQAKAV  708
            LS+DYSQIELRVLAHI+ DE +  AF +G DIHT+TAM+VFG++ A +V +  RR+AKAV
Sbjct  653  LSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAV  712

Query  709  NFGIVYGISDYGLSQSLGITRKKAKAFIDDYLASFPGVKQYMSDIVKDAKALGYVETLLH  768
            NFGIVYGISD+GLS++LGITRK++K++ID Y+  +PG+K YM ++V++AK  GYVETL+ 
Sbjct  713  NFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFK  772

Query  769  RRRYIPDITSRNFNLRGFAERTAMNTPIQGSAADIIKLAMVKFAQKMKETTYQAKLLLQV  828
            RRR +PDI SRNFN+R+FAERTA+N+PIQGSAADI+K+AM+++ + ++   ++AK+LLQV
Sbjct  773  RRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQV  832

Query  829  HDELIFEVPKsevdsfsefveeIMENALQLDVPLKVDSSYGATWYDAK  876
            HDE+++EVP+ E+ ++  +V + ME A++L VPL VD S G +WY+AK
Sbjct  833  HDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

369) polA in NC_020533


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  676 bits (2556),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 426/888 (48%), Positives = 638/888 (72%), Gaps = 25/888 (2%)

Query  2    NKLVLIDGNSLSFRAFYAL----PLLSNKAGIHTNAVYGFAMLLEKILKEEKPNHFLVAF  57
            NKL+LIDG+S++FRAF+AL      + N +G+HTNA+YGF ++L+ ++K  +P H LVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  58   DAGKTTFRHEKYSEYKGGRQKTPPELSEQFPYIRQLLDAYHIKRYELDNYEADDIIGTLS  117
            DAGKTTFR E Y++YK+GR KTP E+ EQF+YIR++L A  I  YEL++YEADDIIGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  118  KEADKAG--FQTIIITGDRDLTQLATDNVTIYYTKKGVTDVDHYTPDFIAEKYNGLTPNQ  175
            K A+++   F+  I++GD+DL QL+ +N  +  +KKGV++ +++TP ++ EK  GLTPNQ
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEK-MGLTPNQ  183

Query  176  IIDMKGLMGDTSDNIPGVAGVGEKTAIKLLNQFDTVEGVYEHLDEISGKKLKEKLQNSKE  235
            +ID+K+LMGD SDNIPGV+ +GEKT++KLL++F+++EG+YEH+D +   K+KE+L N ++
Sbjct  184  FIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRD  243

Query  236  DALMSKELATINVDSPIEVKLEDTLMTHQDeqqekielfkklefkqllSDIDQSASVEDA  295
            +A++SK LATIN  SPI + L+D +    D              +   + +    + E  
Sbjct  244  QAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKG-LASQMPQEPV  302

Query  296  IEKTFEIETSFDNIDFTSLKEAAIHFELDGGNYLRNNILKFSLFTGEKHIVINAD----D  351
               +++  T+     F++  E  + FE   +NY R+ I+ F+   GE +I  ++D     
Sbjct  303  AVISYQEVTNVSADLFSA--EDIFYFETLRDNYHREAIIGFAWGHGE-QIYASTDLSLLA  359

Query  352  INNYAELVSWLENPNTKKVVYDAKKTYVASHRLGIDIQNISFDIMLASYIIDPSRTISDV  411
             +++ ++   +++P +    YD K++ V   +LGI++   S+D  LA+Y++      +++
Sbjct  360  TDSFKQV---FQKPIA---TYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NEL  412

Query  412  QSVVSLYGQSFVKDDVSIYGKGKKFKVPEDDVLNPYVASITDAIYFAKPNMDKQLEEYNQ  471
             ++  ++ +  + +D ++YGKG K  VP+ DVL   +A     +  +K++M  +L   +Q
Sbjct  413  STIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQ  472

Query  472  VELLADLELPLAKILSEMEEIGIFTDVHDLEEMEKEIQEKLDVLIRNIHDAAGEDFNINS  531
            ++L  ++ELPLA++L+ ME  GI  +   L++M  + +  ++ L ++I D AG++FNINS
Sbjct  473  LDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINS  532

Query  532  PKQLGVVLFETLQLP--VIKKTKTGYSTAVDVLEQLQGEHPIIDYILEYRQLSKLQSTYV  589
            PKQLG +LFE +QLP  + KKTKTGYSTAVDVLE+L    PI+  IL+YRQ++KLQSTYV
Sbjct  533  PKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYV  592

Query  590  EGLQKVISDDQRIHTRFNQTLAQTGRLSSVDPNLQNIPVRLEEGRKIRKAFKPTSKDSVI  649
             GLQ  I  D +IHTR+ Q L+QTGRLSSVDPNLQNIP+RLE+GR IRKAF P+  D+V+
Sbjct  593  IGLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVL  652

Query  650  LSADYSQIELRVLAHITQDESMKEAFINGDDIHTATAMKVFGVE-ADQVDSLMRRQAKAV  708
            LS+DYSQIELRVLAHI+ DE +  AF +G DIHT+TAM+VFG++ A +V +  RR+AKAV
Sbjct  653  LSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAV  712

Query  709  NFGIVYGISDYGLSQSLGITRKKAKAFIDDYLASFPGVKQYMSDIVKDAKALGYVETLLH  768
            NFGIVYGISD+GLS++LGITRK++K++ID Y+  +PG+K YM ++V++AK  GYVETL+ 
Sbjct  713  NFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFK  772

Query  769  RRRYIPDITSRNFNLRGFAERTAMNTPIQGSAADIIKLAMVKFAQKMKETTYQAKLLLQV  828
            RRR +PDI SRNFN+R+FAERTA+N+PIQGSAADI+K+AM+++ + ++   ++AK+LLQV
Sbjct  773  RRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQV  832

Query  829  HDELIFEVPKsevdsfsefveeIMENALQLDVPLKVDSSYGATWYDAK  876
            HDE+++EVP+ E+ ++  +V + ME A++L VPL VD S G +WY+AK
Sbjct  833  HDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

370) polA in NC_020537


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  676 bits (2556),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 426/888 (48%), Positives = 638/888 (72%), Gaps = 25/888 (2%)

Query  2    NKLVLIDGNSLSFRAFYAL----PLLSNKAGIHTNAVYGFAMLLEKILKEEKPNHFLVAF  57
            NKL+LIDG+S++FRAF+AL      + N +G+HTNA+YGF ++L+ ++K  +P H LVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  58   DAGKTTFRHEKYSEYKGGRQKTPPELSEQFPYIRQLLDAYHIKRYELDNYEADDIIGTLS  117
            DAGKTTFR E Y++YK+GR KTP E+ EQF+YIR++L A  I  YEL++YEADDIIGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  118  KEADKAG--FQTIIITGDRDLTQLATDNVTIYYTKKGVTDVDHYTPDFIAEKYNGLTPNQ  175
            K A+++   F+  I++GD+DL QL+ +N  +  +KKGV++ +++TP ++ EK  GLTPNQ
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEK-MGLTPNQ  183

Query  176  IIDMKGLMGDTSDNIPGVAGVGEKTAIKLLNQFDTVEGVYEHLDEISGKKLKEKLQNSKE  235
            +ID+K+LMGD SDNIPGV+ +GEKT++KLL++F+++EG+YEH+D +   K+KE+L N ++
Sbjct  184  FIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRD  243

Query  236  DALMSKELATINVDSPIEVKLEDTLMTHQDeqqekielfkklefkqllSDIDQSASVEDA  295
            +A++SK LATIN  SPI + L+D +    D              +   + +    + E  
Sbjct  244  QAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKG-LASQMPQEPV  302

Query  296  IEKTFEIETSFDNIDFTSLKEAAIHFELDGGNYLRNNILKFSLFTGEKHIVINAD----D  351
               +++  T+     F++  E  + FE   +NY R+ I+ F+   GE +I  ++D     
Sbjct  303  AVISYQEVTNVSADLFSA--EDIFYFETLRDNYHREAIIGFAWGHGE-QIYASTDLSLLA  359

Query  352  INNYAELVSWLENPNTKKVVYDAKKTYVASHRLGIDIQNISFDIMLASYIIDPSRTISDV  411
             +++ ++   +++P +    YD K++ V   +LGI++   S+D  LA+Y++      +++
Sbjct  360  TDSFKQV---FQKPIA---TYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NEL  412

Query  412  QSVVSLYGQSFVKDDVSIYGKGKKFKVPEDDVLNPYVASITDAIYFAKPNMDKQLEEYNQ  471
             ++  ++ +  + +D ++YGKG K  VP+ DVL   +A     +  +K++M  +L   +Q
Sbjct  413  STIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQ  472

Query  472  VELLADLELPLAKILSEMEEIGIFTDVHDLEEMEKEIQEKLDVLIRNIHDAAGEDFNINS  531
            ++L  ++ELPLA++L+ ME  GI  +   L++M  + +  ++ L ++I D AG++FNINS
Sbjct  473  LDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINS  532

Query  532  PKQLGVVLFETLQLP--VIKKTKTGYSTAVDVLEQLQGEHPIIDYILEYRQLSKLQSTYV  589
            PKQLG +LFE +QLP  + KKTKTGYSTAVDVLE+L    PI+  IL+YRQ++KLQSTYV
Sbjct  533  PKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYV  592

Query  590  EGLQKVISDDQRIHTRFNQTLAQTGRLSSVDPNLQNIPVRLEEGRKIRKAFKPTSKDSVI  649
             GLQ  I  D +IHTR+ Q L+QTGRLSSVDPNLQNIP+RLE+GR IRKAF P+  D+V+
Sbjct  593  IGLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVL  652

Query  650  LSADYSQIELRVLAHITQDESMKEAFINGDDIHTATAMKVFGVE-ADQVDSLMRRQAKAV  708
            LS+DYSQIELRVLAHI+ DE +  AF +G DIHT+TAM+VFG++ A +V +  RR+AKAV
Sbjct  653  LSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAV  712

Query  709  NFGIVYGISDYGLSQSLGITRKKAKAFIDDYLASFPGVKQYMSDIVKDAKALGYVETLLH  768
            NFGIVYGISD+GLS++LGITRK++K++ID Y+  +PG+K YM ++V++AK  GYVETL+ 
Sbjct  713  NFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFK  772

Query  769  RRRYIPDITSRNFNLRGFAERTAMNTPIQGSAADIIKLAMVKFAQKMKETTYQAKLLLQV  828
            RRR +PDI SRNFN+R+FAERTA+N+PIQGSAADI+K+AM+++ + ++   ++AK+LLQV
Sbjct  773  RRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQV  832

Query  829  HDELIFEVPKsevdsfsefveeIMENALQLDVPLKVDSSYGATWYDAK  876
            HDE+++EVP+ E+ ++  +V + ME A++L VPL VD S G +WY+AK
Sbjct  833  HDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

371) polA in NC_020566


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  676 bits (2556),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 426/888 (48%), Positives = 638/888 (72%), Gaps = 25/888 (2%)

Query  2    NKLVLIDGNSLSFRAFYAL----PLLSNKAGIHTNAVYGFAMLLEKILKEEKPNHFLVAF  57
            NKL+LIDG+S++FRAF+AL      + N +G+HTNA+YGF ++L+ ++K  +P H LVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  58   DAGKTTFRHEKYSEYKGGRQKTPPELSEQFPYIRQLLDAYHIKRYELDNYEADDIIGTLS  117
            DAGKTTFR E Y++YK+GR KTP E+ EQF+YIR++L A  I  YEL++YEADDIIGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  118  KEADKAG--FQTIIITGDRDLTQLATDNVTIYYTKKGVTDVDHYTPDFIAEKYNGLTPNQ  175
            K A+++   F+  I++GD+DL QL+ +N  +  +KKGV++ +++TP ++ EK  GLTPNQ
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEK-MGLTPNQ  183

Query  176  IIDMKGLMGDTSDNIPGVAGVGEKTAIKLLNQFDTVEGVYEHLDEISGKKLKEKLQNSKE  235
            +ID+K+LMGD SDNIPGV+ +GEKT++KLL++F+++EG+YEH+D +   K+KE+L N ++
Sbjct  184  FIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRD  243

Query  236  DALMSKELATINVDSPIEVKLEDTLMTHQDeqqekielfkklefkqllSDIDQSASVEDA  295
            +A++SK LATIN  SPI + L+D +    D              +   + +    + E  
Sbjct  244  QAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKG-LASQMPQEPV  302

Query  296  IEKTFEIETSFDNIDFTSLKEAAIHFELDGGNYLRNNILKFSLFTGEKHIVINAD----D  351
               +++  T+     F++  E  + FE   +NY R+ I+ F+   GE +I  ++D     
Sbjct  303  AVISYQEVTNVSADLFSA--EDIFYFETLRDNYHREAIIGFAWGHGE-QIYASTDLSLLA  359

Query  352  INNYAELVSWLENPNTKKVVYDAKKTYVASHRLGIDIQNISFDIMLASYIIDPSRTISDV  411
             +++ ++   +++P +    YD K++ V   +LGI++   S+D  LA+Y++      +++
Sbjct  360  TDSFKQV---FQKPIA---TYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NEL  412

Query  412  QSVVSLYGQSFVKDDVSIYGKGKKFKVPEDDVLNPYVASITDAIYFAKPNMDKQLEEYNQ  471
             ++  ++ +  + +D ++YGKG K  VP+ DVL   +A     +  +K++M  +L   +Q
Sbjct  413  STIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQ  472

Query  472  VELLADLELPLAKILSEMEEIGIFTDVHDLEEMEKEIQEKLDVLIRNIHDAAGEDFNINS  531
            ++L  ++ELPLA++L+ ME  GI  +   L++M  + +  ++ L ++I D AG++FNINS
Sbjct  473  LDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINS  532

Query  532  PKQLGVVLFETLQLP--VIKKTKTGYSTAVDVLEQLQGEHPIIDYILEYRQLSKLQSTYV  589
            PKQLG +LFE +QLP  + KKTKTGYSTAVDVLE+L    PI+  IL+YRQ++KLQSTYV
Sbjct  533  PKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYV  592

Query  590  EGLQKVISDDQRIHTRFNQTLAQTGRLSSVDPNLQNIPVRLEEGRKIRKAFKPTSKDSVI  649
             GLQ  I  D +IHTR+ Q L+QTGRLSSVDPNLQNIP+RLE+GR IRKAF P+  D+V+
Sbjct  593  IGLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVL  652

Query  650  LSADYSQIELRVLAHITQDESMKEAFINGDDIHTATAMKVFGVE-ADQVDSLMRRQAKAV  708
            LS+DYSQIELRVLAHI+ DE +  AF +G DIHT+TAM+VFG++ A +V +  RR+AKAV
Sbjct  653  LSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAV  712

Query  709  NFGIVYGISDYGLSQSLGITRKKAKAFIDDYLASFPGVKQYMSDIVKDAKALGYVETLLH  768
            NFGIVYGISD+GLS++LGITRK++K++ID Y+  +PG+K YM ++V++AK  GYVETL+ 
Sbjct  713  NFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFK  772

Query  769  RRRYIPDITSRNFNLRGFAERTAMNTPIQGSAADIIKLAMVKFAQKMKETTYQAKLLLQV  828
            RRR +PDI SRNFN+R+FAERTA+N+PIQGSAADI+K+AM+++ + ++   ++AK+LLQV
Sbjct  773  RRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQV  832

Query  829  HDELIFEVPKsevdsfsefveeIMENALQLDVPLKVDSSYGATWYDAK  876
            HDE+++EVP+ E+ ++  +V + ME A++L VPL VD S G +WY+AK
Sbjct  833  HDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

372) polA in NC_020536


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  676 bits (2556),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 426/888 (48%), Positives = 638/888 (72%), Gaps = 25/888 (2%)

Query  2    NKLVLIDGNSLSFRAFYAL----PLLSNKAGIHTNAVYGFAMLLEKILKEEKPNHFLVAF  57
            NKL+LIDG+S++FRAF+AL      + N +G+HTNA+YGF ++L+ ++K  +P H LVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  58   DAGKTTFRHEKYSEYKGGRQKTPPELSEQFPYIRQLLDAYHIKRYELDNYEADDIIGTLS  117
            DAGKTTFR E Y++YK+GR KTP E+ EQF+YIR++L A  I  YEL++YEADDIIGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  118  KEADKAG--FQTIIITGDRDLTQLATDNVTIYYTKKGVTDVDHYTPDFIAEKYNGLTPNQ  175
            K A+++   F+  I++GD+DL QL+ +N  +  +KKGV++ +++TP ++ EK  GLTPNQ
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEK-MGLTPNQ  183

Query  176  IIDMKGLMGDTSDNIPGVAGVGEKTAIKLLNQFDTVEGVYEHLDEISGKKLKEKLQNSKE  235
            +ID+K+LMGD SDNIPGV+ +GEKT++KLL++F+++EG+YEH+D +   K+KE+L N ++
Sbjct  184  FIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRD  243

Query  236  DALMSKELATINVDSPIEVKLEDTLMTHQDeqqekielfkklefkqllSDIDQSASVEDA  295
            +A++SK LATIN  SPI + L+D +    D              +   + +    + E  
Sbjct  244  QAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKG-LASQMPQEPV  302

Query  296  IEKTFEIETSFDNIDFTSLKEAAIHFELDGGNYLRNNILKFSLFTGEKHIVINAD----D  351
               +++  T+     F++  E  + FE   +NY R+ I+ F+   GE +I  ++D     
Sbjct  303  AVISYQEVTNVSADLFSA--EDIFYFETLRDNYHREAIIGFAWGHGE-QIYASTDLSLLA  359

Query  352  INNYAELVSWLENPNTKKVVYDAKKTYVASHRLGIDIQNISFDIMLASYIIDPSRTISDV  411
             +++ ++   +++P +    YD K++ V   +LGI++   S+D  LA+Y++      +++
Sbjct  360  TDSFKQV---FQKPIA---TYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NEL  412

Query  412  QSVVSLYGQSFVKDDVSIYGKGKKFKVPEDDVLNPYVASITDAIYFAKPNMDKQLEEYNQ  471
             ++  ++ +  + +D ++YGKG K  VP+ DVL   +A     +  +K++M  +L   +Q
Sbjct  413  STIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQ  472

Query  472  VELLADLELPLAKILSEMEEIGIFTDVHDLEEMEKEIQEKLDVLIRNIHDAAGEDFNINS  531
            ++L  ++ELPLA++L+ ME  GI  +   L++M  + +  ++ L ++I D AG++FNINS
Sbjct  473  LDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINS  532

Query  532  PKQLGVVLFETLQLP--VIKKTKTGYSTAVDVLEQLQGEHPIIDYILEYRQLSKLQSTYV  589
            PKQLG +LFE +QLP  + KKTKTGYSTAVDVLE+L    PI+  IL+YRQ++KLQSTYV
Sbjct  533  PKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYV  592

Query  590  EGLQKVISDDQRIHTRFNQTLAQTGRLSSVDPNLQNIPVRLEEGRKIRKAFKPTSKDSVI  649
             GLQ  I  D +IHTR+ Q L+QTGRLSSVDPNLQNIP+RLE+GR IRKAF P+  D+V+
Sbjct  593  IGLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVL  652

Query  650  LSADYSQIELRVLAHITQDESMKEAFINGDDIHTATAMKVFGVE-ADQVDSLMRRQAKAV  708
            LS+DYSQIELRVLAHI+ DE +  AF +G DIHT+TAM+VFG++ A +V +  RR+AKAV
Sbjct  653  LSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAV  712

Query  709  NFGIVYGISDYGLSQSLGITRKKAKAFIDDYLASFPGVKQYMSDIVKDAKALGYVETLLH  768
            NFGIVYGISD+GLS++LGITRK++K++ID Y+  +PG+K YM ++V++AK  GYVETL+ 
Sbjct  713  NFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFK  772

Query  769  RRRYIPDITSRNFNLRGFAERTAMNTPIQGSAADIIKLAMVKFAQKMKETTYQAKLLLQV  828
            RRR +PDI SRNFN+R+FAERTA+N+PIQGSAADI+K+AM+++ + ++   ++AK+LLQV
Sbjct  773  RRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQV  832

Query  829  HDELIFEVPKsevdsfsefveeIMENALQLDVPLKVDSSYGATWYDAK  876
            HDE+++EVP+ E+ ++  +V + ME A++L VPL VD S G +WY+AK
Sbjct  833  HDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

373) polA in NC_020568


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  676 bits (2556),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 426/888 (48%), Positives = 638/888 (72%), Gaps = 25/888 (2%)

Query  2    NKLVLIDGNSLSFRAFYAL----PLLSNKAGIHTNAVYGFAMLLEKILKEEKPNHFLVAF  57
            NKL+LIDG+S++FRAF+AL      + N +G+HTNA+YGF ++L+ ++K  +P H LVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  58   DAGKTTFRHEKYSEYKGGRQKTPPELSEQFPYIRQLLDAYHIKRYELDNYEADDIIGTLS  117
            DAGKTTFR E Y++YK+GR KTP E+ EQF+YIR++L A  I  YEL++YEADDIIGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  118  KEADKAG--FQTIIITGDRDLTQLATDNVTIYYTKKGVTDVDHYTPDFIAEKYNGLTPNQ  175
            K A+++   F+  I++GD+DL QL+ +N  +  +KKGV++ +++TP ++ EK  GLTPNQ
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEK-MGLTPNQ  183

Query  176  IIDMKGLMGDTSDNIPGVAGVGEKTAIKLLNQFDTVEGVYEHLDEISGKKLKEKLQNSKE  235
            +ID+K+LMGD SDNIPGV+ +GEKT++KLL++F+++EG+YEH+D +   K+KE+L N ++
Sbjct  184  FIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRD  243

Query  236  DALMSKELATINVDSPIEVKLEDTLMTHQDeqqekielfkklefkqllSDIDQSASVEDA  295
            +A++SK LATIN  SPI + L+D +    D              +   + +    + E  
Sbjct  244  QAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKG-LASQMPQEPV  302

Query  296  IEKTFEIETSFDNIDFTSLKEAAIHFELDGGNYLRNNILKFSLFTGEKHIVINAD----D  351
               +++  T+     F++  E  + FE   +NY R+ I+ F+   GE +I  ++D     
Sbjct  303  AVISYQEVTNVSADLFSA--EDIFYFETLRDNYHREAIIGFAWGHGE-QIYASTDLSLLA  359

Query  352  INNYAELVSWLENPNTKKVVYDAKKTYVASHRLGIDIQNISFDIMLASYIIDPSRTISDV  411
             +++ ++   +++P +    YD K++ V   +LGI++   S+D  LA+Y++      +++
Sbjct  360  TDSFKQV---FQKPIA---TYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NEL  412

Query  412  QSVVSLYGQSFVKDDVSIYGKGKKFKVPEDDVLNPYVASITDAIYFAKPNMDKQLEEYNQ  471
             ++  ++ +  + +D ++YGKG K  VP+ DVL   +A     +  +K++M  +L   +Q
Sbjct  413  STIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQ  472

Query  472  VELLADLELPLAKILSEMEEIGIFTDVHDLEEMEKEIQEKLDVLIRNIHDAAGEDFNINS  531
            ++L  ++ELPLA++L+ ME  GI  +   L++M  + +  ++ L ++I D AG++FNINS
Sbjct  473  LDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINS  532

Query  532  PKQLGVVLFETLQLP--VIKKTKTGYSTAVDVLEQLQGEHPIIDYILEYRQLSKLQSTYV  589
            PKQLG +LFE +QLP  + KKTKTGYSTAVDVLE+L    PI+  IL+YRQ++KLQSTYV
Sbjct  533  PKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYV  592

Query  590  EGLQKVISDDQRIHTRFNQTLAQTGRLSSVDPNLQNIPVRLEEGRKIRKAFKPTSKDSVI  649
             GLQ  I  D +IHTR+ Q L+QTGRLSSVDPNLQNIP+RLE+GR IRKAF P+  D+V+
Sbjct  593  IGLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVL  652

Query  650  LSADYSQIELRVLAHITQDESMKEAFINGDDIHTATAMKVFGVE-ADQVDSLMRRQAKAV  708
            LS+DYSQIELRVLAHI+ DE +  AF +G DIHT+TAM+VFG++ A +V +  RR+AKAV
Sbjct  653  LSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAV  712

Query  709  NFGIVYGISDYGLSQSLGITRKKAKAFIDDYLASFPGVKQYMSDIVKDAKALGYVETLLH  768
            NFGIVYGISD+GLS++LGITRK++K++ID Y+  +PG+K YM ++V++AK  GYVETL+ 
Sbjct  713  NFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFK  772

Query  769  RRRYIPDITSRNFNLRGFAERTAMNTPIQGSAADIIKLAMVKFAQKMKETTYQAKLLLQV  828
            RRR +PDI SRNFN+R+FAERTA+N+PIQGSAADI+K+AM+++ + ++   ++AK+LLQV
Sbjct  773  RRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQV  832

Query  829  HDELIFEVPKsevdsfsefveeIMENALQLDVPLKVDSSYGATWYDAK  876
            HDE+++EVP+ E+ ++  +V + ME A++L VPL VD S G +WY+AK
Sbjct  833  HDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

374) polA in NC_018608


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  675 bits (2552),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 427/888 (49%), Positives = 639/888 (72%), Gaps = 25/888 (2%)

Query  2    NKLVLIDGNSLSFRAFYAL----PLLSNKAGIHTNAVYGFAMLLEKILKEEKPNHFLVAF  57
            NKL+LIDG+S++FRAF+AL      + N +G+HTNA+YGF ++L+ ++K  +P H LVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  58   DAGKTTFRHEKYSEYKGGRQKTPPELSEQFPYIRQLLDAYHIKRYELDNYEADDIIGTLS  117
            DAGKTTFR E Y++YK+GR KTP E+ EQF+YIR++L A  I  YEL++YEADDIIGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  118  KEADKAG--FQTIIITGDRDLTQLATDNVTIYYTKKGVTDVDHYTPDFIAEKYNGLTPNQ  175
            K A+++   F+  I++GD+DL QL+ +N  +  +KKGV++ +++TP ++ EK  GLTPNQ
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEK-MGLTPNQ  183

Query  176  IIDMKGLMGDTSDNIPGVAGVGEKTAIKLLNQFDTVEGVYEHLDEISGKKLKEKLQNSKE  235
            +ID+K+LMGD SDNIPGV+ +GEKT++KLL++F+++EG+YEH+D +   K+KE+L N ++
Sbjct  184  FIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRD  243

Query  236  DALMSKELATINVDSPIEVKLEDTLMTHQDeqqekielfkklefkqllADIDQSASGEDA  295
            +A++SK LATIN  SPI + L+D +    D              +   +   Q +    A
Sbjct  244  QAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEPVA  303

Query  296  IEKTFEIETSFDNVDFTSLEEAAIHFELDGGNYLRNNILKFSLFTGEKHIVINAD----D  351
            +  +++  T+     F++  E  + FE   +NY R+ I+ F+   GE +I  ++D     
Sbjct  304  V-ISYQEVTNVSADLFSA--EDIFYFETLRDNYHREAIIGFAWGHGE-QIYASTDLSLLA  359

Query  352  INNYAELVSWLENPNTKKVVYDAKKTYVASHRLGIDIQNISFDIMLASYIIDPSRTISDV  411
             +++ ++   +++P +    YD K++ V   +LGI++   S+D  LA+Y++      +++
Sbjct  360  TDSFKQV---FQKPIA---TYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NEL  412

Query  412  QSVVSLYGQSFVKDDVSIYGKGKKFKVPEDDVLNPYVAFITDAIYFAKPNMDKQLEEYNQ  471
             ++  ++ +  + +D ++YGKG K  VP+ DVL   +A     +  +K++M  +L   +Q
Sbjct  413  STIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQ  472

Query  472  VELLADLELPLAKILSEMEEIGIYTDVHDLEEMEKEIQEKLDVLIRNIHDAAGEDFNINS  531
            ++L  ++ELPLA++L+ ME  GI  +   L++M  + +  ++ L ++I D AG++FNINS
Sbjct  473  LDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINS  532

Query  532  PKQLGVVLFETLQLP--VIKKTKTGYSTAVDVLEQLQGEHPIIDYILEYRQLSKLQSTYV  589
            PKQLG +LFE +QLP  + KKTKTGYSTAVDVLE+L    PI+  IL+YRQ++KLQSTYV
Sbjct  533  PKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYV  592

Query  590  EGLQKVISDDQRIHTRFNQTLAQTGRLSSVDPNLQNIPVRLEEGRKIRKAFKPTSKDSVI  649
             GLQ  I  D +IHTR+ Q L+QTGRLSSVDPNLQNIP+RLE+GR IRKAF P+  D+V+
Sbjct  593  IGLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVL  652

Query  650  LSADYSQIELRVLAHITQDESMKEAFINGDDIHTATAMKVFGVE-ADQVDSLMRRQAKAV  708
            LS+DYSQIELRVLAHI+ DE +  AF +G DIHT+TAM+VFG++ A +V +  RR+AKAV
Sbjct  653  LSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAV  712

Query  709  NFGIVYGISDYGLSQSLGITRKKAKAFIDDYLASFPGVKQYMSDIVKDAKALGYVETLLH  768
            NFGIVYGISD+GLS++LGITRK++K++ID Y+  +PG+K YM ++V++AK  GYVETL+ 
Sbjct  713  NFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFK  772

Query  769  RRRYIPDITSRNFNLRGFAERTAMNTPIQGSAADIIKLAMVKFAQKMKETTYQAKLLLQV  828
            RRR +PDI SRNFN+R+FAERTA+N+PIQGSAADI+K+AM+++ + ++   ++AK+LLQV
Sbjct  773  RRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQV  832

Query  829  HDELIFEVPKsevdsfsefveeIMENALQLDVPLKVDSSYGATWYDAK  876
            HDE+++EVP+ E+ ++  +V + ME A++L VPL VD S G +WY+AK
Sbjct  833  HDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

375) ST398NM01_1744 in NC_017673


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  675 bits (2552),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 427/888 (49%), Positives = 639/888 (72%), Gaps = 25/888 (2%)

Query  2    NKLVLIDGNSLSFRAFYAL----PLLSNKAGIHTNAVYGFAMLLEKILKEEKPNHFLVAF  57
            NKL+LIDG+S++FRAF+AL      + N +G+HTNA+YGF ++L+ ++K  +P H LVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  58   DAGKTTFRHEKYSEYKGGRQKTPPELSEQFPYIRQLLDAYHIKRYELDNYEADDIIGTLS  117
            DAGKTTFR E Y++YK+GR KTP E+ EQF+YIR++L A  I  YEL++YEADDIIGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  118  KEADKAG--FQTIIITGDRDLTQLATDNVTIYYTKKGVTDVDHYTPDFIAEKYNGLTPNQ  175
            K A+++   F+  I++GD+DL QL+ +N  +  +KKGV++ +++TP ++ EK  GLTPNQ
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEK-MGLTPNQ  183

Query  176  IIDMKGLMGDTSDNIPGVAGVGEKTAIKLLNQFDTVEGVYEHLDEISGKKLKEKLQNSKE  235
            +ID+K+LMGD SDNIPGV+ +GEKT++KLL++F+++EG+YEH+D +   K+KE+L N ++
Sbjct  184  FIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRD  243

Query  236  DALMSKELATINVDSPIEVKLEDTLMTHQDeqqekielfkklefkqllADIDQSASGEDA  295
            +A++SK LATIN  SPI + L+D +    D              +   +   Q +    A
Sbjct  244  QAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEPVA  303

Query  296  IEKTFEIETSFDNVDFTSLEEAAIHFELDGGNYLRNNILKFSLFTGEKHIVINAD----D  351
            +  +++  T+     F++  E  + FE   +NY R+ I+ F+   GE +I  ++D     
Sbjct  304  V-ISYQEVTNVSADLFSA--EDIFYFETLRDNYHREAIIGFAWGHGE-QIYASTDLSLLA  359

Query  352  INNYAELVSWLENPNTKKVVYDAKKTYVASHRLGIDIQNISFDIMLASYIIDPSRTISDV  411
             +++ ++   +++P +    YD K++ V   +LGI++   S+D  LA+Y++      +++
Sbjct  360  TDSFKQV---FQKPIA---TYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NEL  412

Query  412  QSVVSLYGQSFVKDDVSIYGKGKKFKVPEDDVLNPYVAFITDAIYFAKPNMDKQLEEYNQ  471
             ++  ++ +  + +D ++YGKG K  VP+ DVL   +A     +  +K++M  +L   +Q
Sbjct  413  STIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQ  472

Query  472  VELLADLELPLAKILSEMEEIGIYTDVHDLEEMEKEIQEKLDVLIRNIHDAAGEDFNINS  531
            ++L  ++ELPLA++L+ ME  GI  +   L++M  + +  ++ L ++I D AG++FNINS
Sbjct  473  LDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINS  532

Query  532  PKQLGVVLFETLQLP--VIKKTKTGYSTAVDVLEQLQGEHPIIDYILEYRQLSKLQSTYV  589
            PKQLG +LFE +QLP  + KKTKTGYSTAVDVLE+L    PI+  IL+YRQ++KLQSTYV
Sbjct  533  PKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYV  592

Query  590  EGLQKVISDDQRIHTRFNQTLAQTGRLSSVDPNLQNIPVRLEEGRKIRKAFKPTSKDSVI  649
             GLQ  I  D +IHTR+ Q L+QTGRLSSVDPNLQNIP+RLE+GR IRKAF P+  D+V+
Sbjct  593  IGLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVL  652

Query  650  LSADYSQIELRVLAHITQDESMKEAFINGDDIHTATAMKVFGVE-ADQVDSLMRRQAKAV  708
            LS+DYSQIELRVLAHI+ DE +  AF +G DIHT+TAM+VFG++ A +V +  RR+AKAV
Sbjct  653  LSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAV  712

Query  709  NFGIVYGISDYGLSQSLGITRKKAKAFIDDYLASFPGVKQYMSDIVKDAKALGYVETLLH  768
            NFGIVYGISD+GLS++LGITRK++K++ID Y+  +PG+K YM ++V++AK  GYVETL+ 
Sbjct  713  NFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFK  772

Query  769  RRRYIPDITSRNFNLRGFAERTAMNTPIQGSAADIIKLAMVKFAQKMKETTYQAKLLLQV  828
            RRR +PDI SRNFN+R+FAERTA+N+PIQGSAADI+K+AM+++ + ++   ++AK+LLQV
Sbjct  773  RRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQV  832

Query  829  HDELIFEVPKsevdsfsefveeIMENALQLDVPLKVDSSYGATWYDAK  876
            HDE+++EVP+ E+ ++  +V + ME A++L VPL VD S G +WY+AK
Sbjct  833  HDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

376) polA in NC_002951


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  675 bits (2554),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 426/888 (48%), Positives = 638/888 (72%), Gaps = 25/888 (2%)

Query  2    NKLVLIDGNSLSFRAFYAL----PLLSNKAGIHTNAVYGFAMLLEKILKEEKPNHFLVAF  57
            NKL+LIDG+S++FRAF+AL      + N +G+HTNA+YGF ++L+ ++K  +P H LVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  58   DAGKTTFRHEKYSEYKGGRQKTPPELSEQFPYIRQLLDAYHIKRYELDNYEADDIIGTLS  117
            DAGKTTFR E Y++YK+GR KTP E+ EQF+YIR++L A  I  YEL++YEADDIIGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  118  KEADKAG--FQTIIITGDRDLTQLATDNVTIYYTKKGVTDVDHYTPDFIAEKYNGLTPNQ  175
            K A+++   F+  I++GD+DL QL+ +N  +  +KKGV++ +++TP ++ EK  GLTPNQ
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEK-MGLTPNQ  183

Query  176  IIDMKGLMGDTSDNIPGVAGVGEKTAIKLLNQFDTVEGVYEHLDEISGKKLKEKLQNSKE  235
            +ID+K+LMGD SDNIPGV+ +GEKT++KLL++F+++EG+YEH+D +   K+KE+L N ++
Sbjct  184  FIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRD  243

Query  236  DALMSKELATINVDSPIEVKLEDTLMTHQDeqqekielfkklefkqllADIDQSASVEDA  295
            +A++SK LATIN  SPI + L+D +    D              +   + +    + E  
Sbjct  244  QAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKG-LASQMPQEPV  302

Query  296  IEKTFEIETSFDNIDFTSLKEAAIHFELDGGNYLRNNILKFSLFTGEKHIVINAD----D  351
               +++  T+     F++  E  + FE   +NY R+ I+ F+   GE +I  ++D     
Sbjct  303  AVISYQEVTNVSADLFSA--EDIFYFETLRDNYHREAIIGFAWGHGE-QIYASTDLSLLA  359

Query  352  INNYVELVSWLENPNSKKVVYDAKKTYVASHRLGIDIQNISFDIMLASYIIDPSRTISDV  411
             +++ ++   +++P +    YD K++ V   +LGI++   S+D  LA+Y++      +++
Sbjct  360  TDSFKQV---FQKPIA---TYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NEL  412

Query  412  QSVVSLYGQSFVKDDVSIYGKGKKFKVPEDDVLNPYVASITDAIYFAKPNMDKQLEEYNQ  471
             ++  ++ +  + +D ++YGKG K  VP+ DVL   +A     +  +K++M  +L   +Q
Sbjct  413  STIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQ  472

Query  472  VELLADLELPLAKILSEMEEIGIFTDVHDLEEMEKEIQEKLDVLIRNIHDAAGEDFNINS  531
            ++L  ++ELPLA++L+ ME  GI  +   L++M  + +  ++ L ++I D AG++FNINS
Sbjct  473  LDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINS  532

Query  532  PKQLGVVLFETLQLP--VIKKTKTGYSTAVDVLEQLQGEHPIIDYILEYRQLSKLQSTYV  589
            PKQLG +LFE +QLP  + KKTKTGYSTAVDVLE+L    PI+  IL+YRQ++KLQSTYV
Sbjct  533  PKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYV  592

Query  590  EGLQKVISDDQRIHTRFNQTLAQTGRLSSVDPNLQNIPVRLEEGRKIRKAFKPTSKDSVI  649
             GLQ  I  D +IHTR+ Q L+QTGRLSSVDPNLQNIP+RLE+GR IRKAF P+  D+V+
Sbjct  593  IGLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVL  652

Query  650  LSADYSQIELRVLAHITQDESMKEAFINGDDIHTATAMKVFGVE-ADQVDSLMRRQAKAV  708
            LS+DYSQIELRVLAHI+ DE +  AF +G DIHT+TAM+VFG++ A +V +  RR+AKAV
Sbjct  653  LSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAV  712

Query  709  NFGIVYGISDYGLSQSLGITRKKAKAFIDDYLASFPGVKQYMSDIVKDAKALGYVETLLH  768
            NFGIVYGISD+GLS++LGITRK++K++ID Y+  +PG+K YM ++V++AK  GYVETL+ 
Sbjct  713  NFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFK  772

Query  769  RRRYIPDITSRNFNLRGFAERTAMNTPIQGSAADIIKLAMVKFAQKMKETTYQAKLLLQV  828
            RRR +PDI SRNFN+R+FAERTA+N+PIQGSAADI+K+AM+++ + ++   ++AK+LLQV
Sbjct  773  RRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQV  832

Query  829  HDELIFEVPKsevdsfsefveeIMENALQLDVPLKVDSSYGATWYDAK  876
            HDE+++EVP+ E+ ++  +V + ME A++L VPL VD S G +WY+AK
Sbjct  833  HDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

377) polA in NC_017341


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  675 bits (2554),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 426/888 (48%), Positives = 638/888 (72%), Gaps = 25/888 (2%)

Query  2    NKLVLIDGNSLSFRAFYAL----PLLSNKAGIHTNAVYGFAMLLEKILKEEKPNHFLVAF  57
            NKL+LIDG+S++FRAF+AL      + N +G+HTNA+YGF ++L+ ++K  +P H LVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  58   DAGKTTFRHEKYSEYKGGRQKTPPELSEQFPYIRQLLDAYHIKRYELDNYEADDIIGTLS  117
            DAGKTTFR E Y++YK+GR KTP E+ EQF+YIR++L A  I  YEL++YEADDIIGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  118  KEADKAG--FQTIIITGDRDLTQLATDNVTIYYTKKGVTDVDHYTPDFIAEKYNGLTPNQ  175
            K A+++   F+  I++GD+DL QL+ +N  +  +KKGV++ +++TP ++ EK  GLTPNQ
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEK-MGLTPNQ  183

Query  176  IIDMKGLMGDTSDNIPGVAGVGEKTAIKLLNQFDTVEGVYEHLDEISGKKLKEKLQNSKE  235
            +ID+K+LMGD SDNIPGV+ +GEKT++KLL++F+++EG+YEH+D +   K+KE+L N ++
Sbjct  184  FIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRD  243

Query  236  DALMSKELATINVDSPIEVKLEDTLMTHQDeqqekielfkklefkqllADIDQSASVEDA  295
            +A++SK LATIN  SPI + L+D +    D              +   + +    + E  
Sbjct  244  QAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKG-LASQMPQEPV  302

Query  296  IEKTFEIETSFDNIDFTSLKEAAIHFELDGGNYLRNNILKFSLFTGEKHIVINAD----D  351
               +++  T+     F++  E  + FE   +NY R+ I+ F+   GE +I  ++D     
Sbjct  303  AVISYQEVTNVSADLFSA--EDIFYFETLRDNYHREAIIGFAWGHGE-QIYASTDLSLLA  359

Query  352  INNYVELVSWLENPNSKKVVYDAKKTYVASHRLGIDIQNISFDIMLASYIIDPSRTISDV  411
             +++ ++   +++P +    YD K++ V   +LGI++   S+D  LA+Y++      +++
Sbjct  360  TDSFKQV---FQKPIA---TYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NEL  412

Query  412  QSVVSLYGQSFVKDDVSIYGKGKKFKVPEDDVLNPYVASITDAIYFAKPNMDKQLEEYNQ  471
             ++  ++ +  + +D ++YGKG K  VP+ DVL   +A     +  +K++M  +L   +Q
Sbjct  413  STIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQ  472

Query  472  VELLADLELPLAKILSEMEEIGIFTDVHDLEEMEKEIQEKLDVLIRNIHDAAGEDFNINS  531
            ++L  ++ELPLA++L+ ME  GI  +   L++M  + +  ++ L ++I D AG++FNINS
Sbjct  473  LDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINS  532

Query  532  PKQLGVVLFETLQLP--VIKKTKTGYSTAVDVLEQLQGEHPIIDYILEYRQLSKLQSTYV  589
            PKQLG +LFE +QLP  + KKTKTGYSTAVDVLE+L    PI+  IL+YRQ++KLQSTYV
Sbjct  533  PKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYV  592

Query  590  EGLQKVISDDQRIHTRFNQTLAQTGRLSSVDPNLQNIPVRLEEGRKIRKAFKPTSKDSVI  649
             GLQ  I  D +IHTR+ Q L+QTGRLSSVDPNLQNIP+RLE+GR IRKAF P+  D+V+
Sbjct  593  IGLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVL  652

Query  650  LSADYSQIELRVLAHITQDESMKEAFINGDDIHTATAMKVFGVE-ADQVDSLMRRQAKAV  708
            LS+DYSQIELRVLAHI+ DE +  AF +G DIHT+TAM+VFG++ A +V +  RR+AKAV
Sbjct  653  LSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAV  712

Query  709  NFGIVYGISDYGLSQSLGITRKKAKAFIDDYLASFPGVKQYMSDIVKDAKALGYVETLLH  768
            NFGIVYGISD+GLS++LGITRK++K++ID Y+  +PG+K YM ++V++AK  GYVETL+ 
Sbjct  713  NFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFK  772

Query  769  RRRYIPDITSRNFNLRGFAERTAMNTPIQGSAADIIKLAMVKFAQKMKETTYQAKLLLQV  828
            RRR +PDI SRNFN+R+FAERTA+N+PIQGSAADI+K+AM+++ + ++   ++AK+LLQV
Sbjct  773  RRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQV  832

Query  829  HDELIFEVPKsevdsfsefveeIMENALQLDVPLKVDSSYGATWYDAK  876
            HDE+++EVP+ E+ ++  +V + ME A++L VPL VD S G +WY+AK
Sbjct  833  HDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

378) BN843_16900 in NC_021059


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  675 bits (2554),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 426/888 (48%), Positives = 638/888 (72%), Gaps = 25/888 (2%)

Query  2    NKLVLIDGNSLSFRAFYAL----PLLSNKAGIHTNAVYGFAMLLEKILKEEKPNHFLVAF  57
            NKL+LIDG+S++FRAF+AL      + N +G+HTNA+YGF ++L+ ++K  +P H LVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  58   DAGKTTFRHEKYSEYKGGRQKTPPELSEQFPYIRQLLDAYHIKRYELDNYEADDIIGTLS  117
            DAGKTTFR E Y++YK+GR KTP E+ EQF+YIR++L A  I  YEL++YEADDIIGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  118  KEADKAG--FQTIIITGDRDLTQLATDNVTIYYTKKGVTDVDHYTPDFIAEKYNGLTPNQ  175
            K A+++   F+  I++GD+DL QL+ +N  +  +KKGV++ +++TP ++ EK  GLTPNQ
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEK-MGLTPNQ  183

Query  176  IIDMKGLMGDTSDNIPGVAGVGEKTAIKLLNQFDTVEGVYEHLDEISGKKLKEKLQNSKE  235
            +ID+K+LMGD SDNIPGV+ +GEKT++KLL++F+++EG+YEH+D +   K+KE+L N ++
Sbjct  184  FIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRD  243

Query  236  DALMSKELATINVDSPIEVKLEDTLMTHQDeqqekielfkklefkqllADIDQSASVEDA  295
            +A++SK LATIN  SPI + L+D +    D              +   + +    + E  
Sbjct  244  QAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKG-LASQMPQEPV  302

Query  296  IEKTFEIETSFDNIDFTSLKEAAIHFELDGGNYLRNNILKFSLFTGEKHIVINAD----D  351
               +++  T+     F++  E  + FE   +NY R+ I+ F+   GE +I  ++D     
Sbjct  303  AVISYQEVTNVSADLFSA--EDIFYFETLRDNYHREAIIGFAWGHGE-QIYASTDLSLLA  359

Query  352  INNYVELVSWLENPNSKKVVYDAKKTYVASHRLGIDIQNISFDIMLASYIIDPSRTISDV  411
             +++ ++   +++P +    YD K++ V   +LGI++   S+D  LA+Y++      +++
Sbjct  360  TDSFKQV---FQKPIA---TYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NEL  412

Query  412  QSVVSLYGQSFVKDDVSIYGKGKKFKVPEDDVLNPYVASITDAIYFAKPNMDKQLEEYNQ  471
             ++  ++ +  + +D ++YGKG K  VP+ DVL   +A     +  +K++M  +L   +Q
Sbjct  413  STIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQ  472

Query  472  VELLADLELPLAKILSEMEEIGIFTDVHDLEEMEKEIQEKLDVLIRNIHDAAGEDFNINS  531
            ++L  ++ELPLA++L+ ME  GI  +   L++M  + +  ++ L ++I D AG++FNINS
Sbjct  473  LDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINS  532

Query  532  PKQLGVVLFETLQLP--VIKKTKTGYSTAVDVLEQLQGEHPIIDYILEYRQLSKLQSTYV  589
            PKQLG +LFE +QLP  + KKTKTGYSTAVDVLE+L    PI+  IL+YRQ++KLQSTYV
Sbjct  533  PKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYV  592

Query  590  EGLQKVISDDQRIHTRFNQTLAQTGRLSSVDPNLQNIPVRLEEGRKIRKAFKPTSKDSVI  649
             GLQ  I  D +IHTR+ Q L+QTGRLSSVDPNLQNIP+RLE+GR IRKAF P+  D+V+
Sbjct  593  IGLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVL  652

Query  650  LSADYSQIELRVLAHITQDESMKEAFINGDDIHTATAMKVFGVE-ADQVDSLMRRQAKAV  708
            LS+DYSQIELRVLAHI+ DE +  AF +G DIHT+TAM+VFG++ A +V +  RR+AKAV
Sbjct  653  LSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAV  712

Query  709  NFGIVYGISDYGLSQSLGITRKKAKAFIDDYLASFPGVKQYMSDIVKDAKALGYVETLLH  768
            NFGIVYGISD+GLS++LGITRK++K++ID Y+  +PG+K YM ++V++AK  GYVETL+ 
Sbjct  713  NFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFK  772

Query  769  RRRYIPDITSRNFNLRGFAERTAMNTPIQGSAADIIKLAMVKFAQKMKETTYQAKLLLQV  828
            RRR +PDI SRNFN+R+FAERTA+N+PIQGSAADI+K+AM+++ + ++   ++AK+LLQV
Sbjct  773  RRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQV  832

Query  829  HDELIFEVPKsevdsfsefveeIMENALQLDVPLKVDSSYGATWYDAK  876
            HDE+++EVP+ E+ ++  +V + ME A++L VPL VD S G +WY+AK
Sbjct  833  HDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

379) SAS1618 in NC_002953


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  675 bits (2554),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 426/888 (48%), Positives = 638/888 (72%), Gaps = 25/888 (2%)

Query  2    NKLVLIDGNSLSFRAFYAL----PLLSNKAGIHTNAVYGFAMLLEKILKEEKPNHFLVAF  57
            NKL+LIDG+S++FRAF+AL      + N +G+HTNA+YGF ++L+ ++K  +P H LVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  58   DAGKTTFRHEKYSEYKGGRQKTPPELSEQFPYIRQLLDAYHIKRYELDNYEADDIIGTLS  117
            DAGKTTFR E Y++YK+GR KTP E+ EQF+YIR++L A  I  YEL++YEADDIIGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  118  KEADKAG--FQTIIITGDRDLTQLATDNVTIYYTKKGVTDVDHYTPDFIAEKYNGLTPNQ  175
            K A+++   F+  I++GD+DL QL+ +N  +  +KKGV++ +++TP ++ EK  GLTPNQ
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEK-MGLTPNQ  183

Query  176  IIDMKGLMGDTSDNIPGVAGVGEKTAIKLLNQFDTVEGVYEHLDEISGKKLKEKLQNSKE  235
            +ID+K+LMGD SDNIPGV+ +GEKT++KLL++F+++EG+YEH+D +   K+KE+L N ++
Sbjct  184  FIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRD  243

Query  236  DALMSKELATINVDSPIEVKLEDTLMTHQDeqqekielfkklefkqllADIDQSASVEDA  295
            +A++SK LATIN  SPI + L+D +    D              +   + +    + E  
Sbjct  244  QAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKG-LASQMPQEPV  302

Query  296  IEKTFEIETSFDNIDFTSLKEAAIHFELDGGNYLRNNILKFSLFTGEKHIVINAD----D  351
               +++  T+     F++  E  + FE   +NY R+ I+ F+   GE +I  ++D     
Sbjct  303  AVISYQEVTNVSADLFSA--EDIFYFETLRDNYHREAIIGFAWGHGE-QIYASTDLSLLA  359

Query  352  INNYVELVSWLENPNSKKVVYDAKKTYVASHRLGIDIQNISFDIMLASYIIDPSRTISDV  411
             +++ ++   +++P +    YD K++ V   +LGI++   S+D  LA+Y++      +++
Sbjct  360  TDSFKQV---FQKPIA---TYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NEL  412

Query  412  QSVVSLYGQSFVKDDVSIYGKGKKFKVPEDDVLNPYVASITDAIYFAKPNMDKQLEEYNQ  471
             ++  ++ +  + +D ++YGKG K  VP+ DVL   +A     +  +K++M  +L   +Q
Sbjct  413  STIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQ  472

Query  472  VELLADLELPLAKILSEMEEIGIFTDVHDLEEMEKEIQEKLDVLIRNIHDAAGEDFNINS  531
            ++L  ++ELPLA++L+ ME  GI  +   L++M  + +  ++ L ++I D AG++FNINS
Sbjct  473  LDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINS  532

Query  532  PKQLGVVLFETLQLP--VIKKTKTGYSTAVDVLEQLQGEHPIIDYILEYRQLSKLQSTYV  589
            PKQLG +LFE +QLP  + KKTKTGYSTAVDVLE+L    PI+  IL+YRQ++KLQSTYV
Sbjct  533  PKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYV  592

Query  590  EGLQKVISDDQRIHTRFNQTLAQTGRLSSVDPNLQNIPVRLEEGRKIRKAFKPTSKDSVI  649
             GLQ  I  D +IHTR+ Q L+QTGRLSSVDPNLQNIP+RLE+GR IRKAF P+  D+V+
Sbjct  593  IGLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVL  652

Query  650  LSADYSQIELRVLAHITQDESMKEAFINGDDIHTATAMKVFGVE-ADQVDSLMRRQAKAV  708
            LS+DYSQIELRVLAHI+ DE +  AF +G DIHT+TAM+VFG++ A +V +  RR+AKAV
Sbjct  653  LSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAV  712

Query  709  NFGIVYGISDYGLSQSLGITRKKAKAFIDDYLASFPGVKQYMSDIVKDAKALGYVETLLH  768
            NFGIVYGISD+GLS++LGITRK++K++ID Y+  +PG+K YM ++V++AK  GYVETL+ 
Sbjct  713  NFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFK  772

Query  769  RRRYIPDITSRNFNLRGFAERTAMNTPIQGSAADIIKLAMVKFAQKMKETTYQAKLLLQV  828
            RRR +PDI SRNFN+R+FAERTA+N+PIQGSAADI+K+AM+++ + ++   ++AK+LLQV
Sbjct  773  RRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQV  832

Query  829  HDELIFEVPKsevdsfsefveeIMENALQLDVPLKVDSSYGATWYDAK  876
            HDE+++EVP+ E+ ++  +V + ME A++L VPL VD S G +WY+AK
Sbjct  833  HDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

380) polA in NC_003923


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  675 bits (2554),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 426/888 (48%), Positives = 638/888 (72%), Gaps = 25/888 (2%)

Query  2    NKLVLIDGNSLSFRAFYAL----PLLSNKAGIHTNAVYGFAMLLEKILKEEKPNHFLVAF  57
            NKL+LIDG+S++FRAF+AL      + N +G+HTNA+YGF ++L+ ++K  +P H LVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  58   DAGKTTFRHEKYSEYKGGRQKTPPELSEQFPYIRQLLDAYHIKRYELDNYEADDIIGTLS  117
            DAGKTTFR E Y++YK+GR KTP E+ EQF+YIR++L A  I  YEL++YEADDIIGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  118  KEADKAG--FQTIIITGDRDLTQLATDNVTIYYTKKGVTDVDHYTPDFIAEKYNGLTPNQ  175
            K A+++   F+  I++GD+DL QL+ +N  +  +KKGV++ +++TP ++ EK  GLTPNQ
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEK-MGLTPNQ  183

Query  176  IIDMKGLMGDTSDNIPGVAGVGEKTAIKLLNQFDTVEGVYEHLDEISGKKLKEKLQNSKE  235
            +ID+K+LMGD SDNIPGV+ +GEKT++KLL++F+++EG+YEH+D +   K+KE+L N ++
Sbjct  184  FIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRD  243

Query  236  DALMSKELATINVDSPIEVKLEDTLMTHQDeqqekielfkklefkqllADIDQSASVEDA  295
            +A++SK LATIN  SPI + L+D +    D              +   + +    + E  
Sbjct  244  QAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKG-LASQMPQEPV  302

Query  296  IEKTFEIETSFDNIDFTSLKEAAIHFELDGGNYLRNNILKFSLFTGEKHIVINAD----D  351
               +++  T+     F++  E  + FE   +NY R+ I+ F+   GE +I  ++D     
Sbjct  303  AVISYQEVTNVSADLFSA--EDIFYFETLRDNYHREAIIGFAWGHGE-QIYASTDLSLLA  359

Query  352  INNYVELVSWLENPNSKKVVYDAKKTYVASHRLGIDIQNISFDIMLASYIIDPSRTISDV  411
             +++ ++   +++P +    YD K++ V   +LGI++   S+D  LA+Y++      +++
Sbjct  360  TDSFKQV---FQKPIA---TYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NEL  412

Query  412  QSVVSLYGQSFVKDDVSIYGKGKKFKVPEDDVLNPYVASITDAIYFAKPNMDKQLEEYNQ  471
             ++  ++ +  + +D ++YGKG K  VP+ DVL   +A     +  +K++M  +L   +Q
Sbjct  413  STIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQ  472

Query  472  VELLADLELPLAKILSEMEEIGIFTDVHDLEEMEKEIQEKLDVLIRNIHDAAGEDFNINS  531
            ++L  ++ELPLA++L+ ME  GI  +   L++M  + +  ++ L ++I D AG++FNINS
Sbjct  473  LDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINS  532

Query  532  PKQLGVVLFETLQLP--VIKKTKTGYSTAVDVLEQLQGEHPIIDYILEYRQLSKLQSTYV  589
            PKQLG +LFE +QLP  + KKTKTGYSTAVDVLE+L    PI+  IL+YRQ++KLQSTYV
Sbjct  533  PKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYV  592

Query  590  EGLQKVISDDQRIHTRFNQTLAQTGRLSSVDPNLQNIPVRLEEGRKIRKAFKPTSKDSVI  649
             GLQ  I  D +IHTR+ Q L+QTGRLSSVDPNLQNIP+RLE+GR IRKAF P+  D+V+
Sbjct  593  IGLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVL  652

Query  650  LSADYSQIELRVLAHITQDESMKEAFINGDDIHTATAMKVFGVE-ADQVDSLMRRQAKAV  708
            LS+DYSQIELRVLAHI+ DE +  AF +G DIHT+TAM+VFG++ A +V +  RR+AKAV
Sbjct  653  LSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAV  712

Query  709  NFGIVYGISDYGLSQSLGITRKKAKAFIDDYLASFPGVKQYMSDIVKDAKALGYVETLLH  768
            NFGIVYGISD+GLS++LGITRK++K++ID Y+  +PG+K YM ++V++AK  GYVETL+ 
Sbjct  713  NFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFK  772

Query  769  RRRYIPDITSRNFNLRGFAERTAMNTPIQGSAADIIKLAMVKFAQKMKETTYQAKLLLQV  828
            RRR +PDI SRNFN+R+FAERTA+N+PIQGSAADI+K+AM+++ + ++   ++AK+LLQV
Sbjct  773  RRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQV  832

Query  829  HDELIFEVPKsevdsfsefveeIMENALQLDVPLKVDSSYGATWYDAK  876
            HDE+++EVP+ E+ ++  +V + ME A++L VPL VD S G +WY+AK
Sbjct  833  HDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

381) SAOUHSC_01797 in NC_007795


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  675 bits (2554),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 426/888 (48%), Positives = 638/888 (72%), Gaps = 25/888 (2%)

Query  2    NKLVLIDGNSLSFRAFYAL----PLLSNKAGIHTNAVYGFAMLLEKILKEEKPNHFLVAF  57
            NKL+LIDG+S++FRAF+AL      + N +G+HTNA+YGF ++L+ ++K  +P H LVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  58   DAGKTTFRHEKYSEYKGGRQKTPPELSEQFPYIRQLLDAYHIKRYELDNYEADDIIGTLS  117
            DAGKTTFR E Y++YK+GR KTP E+ EQF+YIR++L A  I  YEL++YEADDIIGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  118  KEADKAG--FQTIIITGDRDLTQLATDNVTIYYTKKGVTDVDHYTPDFIAEKYNGLTPNQ  175
            K A+++   F+  I++GD+DL QL+ +N  +  +KKGV++ +++TP ++ EK  GLTPNQ
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEK-MGLTPNQ  183

Query  176  IIDMKGLMGDTSDNIPGVAGVGEKTAIKLLNQFDTVEGVYEHLDEISGKKLKEKLQNSKE  235
            +ID+K+LMGD SDNIPGV+ +GEKT++KLL++F+++EG+YEH+D +   K+KE+L N ++
Sbjct  184  FIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRD  243

Query  236  DALMSKELATINVDSPIEVKLEDTLMTHQDeqqekielfkklefkqllADIDQSASVEDA  295
            +A++SK LATIN  SPI + L+D +    D              +   + +    + E  
Sbjct  244  QAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKG-LASQMPQEPV  302

Query  296  IEKTFEIETSFDNIDFTSLKEAAIHFELDGGNYLRNNILKFSLFTGEKHIVINAD----D  351
               +++  T+     F++  E  + FE   +NY R+ I+ F+   GE +I  ++D     
Sbjct  303  AVISYQEVTNVSADLFSA--EDIFYFETLRDNYHREAIIGFAWGHGE-QIYASTDLSLLA  359

Query  352  INNYVELVSWLENPNSKKVVYDAKKTYVASHRLGIDIQNISFDIMLASYIIDPSRTISDV  411
             +++ ++   +++P +    YD K++ V   +LGI++   S+D  LA+Y++      +++
Sbjct  360  TDSFKQV---FQKPIA---TYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NEL  412

Query  412  QSVVSLYGQSFVKDDVSIYGKGKKFKVPEDDVLNPYVASITDAIYFAKPNMDKQLEEYNQ  471
             ++  ++ +  + +D ++YGKG K  VP+ DVL   +A     +  +K++M  +L   +Q
Sbjct  413  STIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQ  472

Query  472  VELLADLELPLAKILSEMEEIGIFTDVHDLEEMEKEIQEKLDVLIRNIHDAAGEDFNINS  531
            ++L  ++ELPLA++L+ ME  GI  +   L++M  + +  ++ L ++I D AG++FNINS
Sbjct  473  LDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINS  532

Query  532  PKQLGVVLFETLQLP--VIKKTKTGYSTAVDVLEQLQGEHPIIDYILEYRQLSKLQSTYV  589
            PKQLG +LFE +QLP  + KKTKTGYSTAVDVLE+L    PI+  IL+YRQ++KLQSTYV
Sbjct  533  PKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYV  592

Query  590  EGLQKVISDDQRIHTRFNQTLAQTGRLSSVDPNLQNIPVRLEEGRKIRKAFKPTSKDSVI  649
             GLQ  I  D +IHTR+ Q L+QTGRLSSVDPNLQNIP+RLE+GR IRKAF P+  D+V+
Sbjct  593  IGLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVL  652

Query  650  LSADYSQIELRVLAHITQDESMKEAFINGDDIHTATAMKVFGVE-ADQVDSLMRRQAKAV  708
            LS+DYSQIELRVLAHI+ DE +  AF +G DIHT+TAM+VFG++ A +V +  RR+AKAV
Sbjct  653  LSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAV  712

Query  709  NFGIVYGISDYGLSQSLGITRKKAKAFIDDYLASFPGVKQYMSDIVKDAKALGYVETLLH  768
            NFGIVYGISD+GLS++LGITRK++K++ID Y+  +PG+K YM ++V++AK  GYVETL+ 
Sbjct  713  NFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFK  772

Query  769  RRRYIPDITSRNFNLRGFAERTAMNTPIQGSAADIIKLAMVKFAQKMKETTYQAKLLLQV  828
            RRR +PDI SRNFN+R+FAERTA+N+PIQGSAADI+K+AM+++ + ++   ++AK+LLQV
Sbjct  773  RRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQV  832

Query  829  HDELIFEVPKsevdsfsefveeIMENALQLDVPLKVDSSYGATWYDAK  876
            HDE+++EVP+ E+ ++  +V + ME A++L VPL VD S G +WY+AK
Sbjct  833  HDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

382) polA in NC_009641


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  675 bits (2554),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 426/888 (48%), Positives = 638/888 (72%), Gaps = 25/888 (2%)

Query  2    NKLVLIDGNSLSFRAFYAL----PLLSNKAGIHTNAVYGFAMLLEKILKEEKPNHFLVAF  57
            NKL+LIDG+S++FRAF+AL      + N +G+HTNA+YGF ++L+ ++K  +P H LVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  58   DAGKTTFRHEKYSEYKGGRQKTPPELSEQFPYIRQLLDAYHIKRYELDNYEADDIIGTLS  117
            DAGKTTFR E Y++YK+GR KTP E+ EQF+YIR++L A  I  YEL++YEADDIIGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  118  KEADKAG--FQTIIITGDRDLTQLATDNVTIYYTKKGVTDVDHYTPDFIAEKYNGLTPNQ  175
            K A+++   F+  I++GD+DL QL+ +N  +  +KKGV++ +++TP ++ EK  GLTPNQ
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEK-MGLTPNQ  183

Query  176  IIDMKGLMGDTSDNIPGVAGVGEKTAIKLLNQFDTVEGVYEHLDEISGKKLKEKLQNSKE  235
            +ID+K+LMGD SDNIPGV+ +GEKT++KLL++F+++EG+YEH+D +   K+KE+L N ++
Sbjct  184  FIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRD  243

Query  236  DALMSKELATINVDSPIEVKLEDTLMTHQDeqqekielfkklefkqllADIDQSASVEDA  295
            +A++SK LATIN  SPI + L+D +    D              +   + +    + E  
Sbjct  244  QAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKG-LASQMPQEPV  302

Query  296  IEKTFEIETSFDNIDFTSLKEAAIHFELDGGNYLRNNILKFSLFTGEKHIVINAD----D  351
               +++  T+     F++  E  + FE   +NY R+ I+ F+   GE +I  ++D     
Sbjct  303  AVISYQEVTNVSADLFSA--EDIFYFETLRDNYHREAIIGFAWGHGE-QIYASTDLSLLA  359

Query  352  INNYVELVSWLENPNSKKVVYDAKKTYVASHRLGIDIQNISFDIMLASYIIDPSRTISDV  411
             +++ ++   +++P +    YD K++ V   +LGI++   S+D  LA+Y++      +++
Sbjct  360  TDSFKQV---FQKPIA---TYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NEL  412

Query  412  QSVVSLYGQSFVKDDVSIYGKGKKFKVPEDDVLNPYVASITDAIYFAKPNMDKQLEEYNQ  471
             ++  ++ +  + +D ++YGKG K  VP+ DVL   +A     +  +K++M  +L   +Q
Sbjct  413  STIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQ  472

Query  472  VELLADLELPLAKILSEMEEIGIFTDVHDLEEMEKEIQEKLDVLIRNIHDAAGEDFNINS  531
            ++L  ++ELPLA++L+ ME  GI  +   L++M  + +  ++ L ++I D AG++FNINS
Sbjct  473  LDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINS  532

Query  532  PKQLGVVLFETLQLP--VIKKTKTGYSTAVDVLEQLQGEHPIIDYILEYRQLSKLQSTYV  589
            PKQLG +LFE +QLP  + KKTKTGYSTAVDVLE+L    PI+  IL+YRQ++KLQSTYV
Sbjct  533  PKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYV  592

Query  590  EGLQKVISDDQRIHTRFNQTLAQTGRLSSVDPNLQNIPVRLEEGRKIRKAFKPTSKDSVI  649
             GLQ  I  D +IHTR+ Q L+QTGRLSSVDPNLQNIP+RLE+GR IRKAF P+  D+V+
Sbjct  593  IGLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVL  652

Query  650  LSADYSQIELRVLAHITQDESMKEAFINGDDIHTATAMKVFGVE-ADQVDSLMRRQAKAV  708
            LS+DYSQIELRVLAHI+ DE +  AF +G DIHT+TAM+VFG++ A +V +  RR+AKAV
Sbjct  653  LSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAV  712

Query  709  NFGIVYGISDYGLSQSLGITRKKAKAFIDDYLASFPGVKQYMSDIVKDAKALGYVETLLH  768
            NFGIVYGISD+GLS++LGITRK++K++ID Y+  +PG+K YM ++V++AK  GYVETL+ 
Sbjct  713  NFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFK  772

Query  769  RRRYIPDITSRNFNLRGFAERTAMNTPIQGSAADIIKLAMVKFAQKMKETTYQAKLLLQV  828
            RRR +PDI SRNFN+R+FAERTA+N+PIQGSAADI+K+AM+++ + ++   ++AK+LLQV
Sbjct  773  RRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQV  832

Query  829  HDELIFEVPKsevdsfsefveeIMENALQLDVPLKVDSSYGATWYDAK  876
            HDE+++EVP+ E+ ++  +V + ME A++L VPL VD S G +WY+AK
Sbjct  833  HDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

383) SAT0131_01792 in NC_017347


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  675 bits (2554),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 426/888 (48%), Positives = 638/888 (72%), Gaps = 25/888 (2%)

Query  2    NKLVLIDGNSLSFRAFYAL----PLLSNKAGIHTNAVYGFAMLLEKILKEEKPNHFLVAF  57
            NKL+LIDG+S++FRAF+AL      + N +G+HTNA+YGF ++L+ ++K  +P H LVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  58   DAGKTTFRHEKYSEYKGGRQKTPPELSEQFPYIRQLLDAYHIKRYELDNYEADDIIGTLS  117
            DAGKTTFR E Y++YK+GR KTP E+ EQF+YIR++L A  I  YEL++YEADDIIGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  118  KEADKAG--FQTIIITGDRDLTQLATDNVTIYYTKKGVTDVDHYTPDFIAEKYNGLTPNQ  175
            K A+++   F+  I++GD+DL QL+ +N  +  +KKGV++ +++TP ++ EK  GLTPNQ
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEK-MGLTPNQ  183

Query  176  IIDMKGLMGDTSDNIPGVAGVGEKTAIKLLNQFDTVEGVYEHLDEISGKKLKEKLQNSKE  235
            +ID+K+LMGD SDNIPGV+ +GEKT++KLL++F+++EG+YEH+D +   K+KE+L N ++
Sbjct  184  FIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRD  243

Query  236  DALMSKELATINVDSPIEVKLEDTLMTHQDeqqekielfkklefkqllADIDQSASVEDA  295
            +A++SK LATIN  SPI + L+D +    D              +   + +    + E  
Sbjct  244  QAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKG-LASQMPQEPV  302

Query  296  IEKTFEIETSFDNIDFTSLKEAAIHFELDGGNYLRNNILKFSLFTGEKHIVINAD----D  351
               +++  T+     F++  E  + FE   +NY R+ I+ F+   GE +I  ++D     
Sbjct  303  AVISYQEVTNVSADLFSA--EDIFYFETLRDNYHREAIIGFAWGHGE-QIYASTDLSLLA  359

Query  352  INNYVELVSWLENPNSKKVVYDAKKTYVASHRLGIDIQNISFDIMLASYIIDPSRTISDV  411
             +++ ++   +++P +    YD K++ V   +LGI++   S+D  LA+Y++      +++
Sbjct  360  TDSFKQV---FQKPIA---TYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NEL  412

Query  412  QSVVSLYGQSFVKDDVSIYGKGKKFKVPEDDVLNPYVASITDAIYFAKPNMDKQLEEYNQ  471
             ++  ++ +  + +D ++YGKG K  VP+ DVL   +A     +  +K++M  +L   +Q
Sbjct  413  STIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQ  472

Query  472  VELLADLELPLAKILSEMEEIGIFTDVHDLEEMEKEIQEKLDVLIRNIHDAAGEDFNINS  531
            ++L  ++ELPLA++L+ ME  GI  +   L++M  + +  ++ L ++I D AG++FNINS
Sbjct  473  LDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINS  532

Query  532  PKQLGVVLFETLQLP--VIKKTKTGYSTAVDVLEQLQGEHPIIDYILEYRQLSKLQSTYV  589
            PKQLG +LFE +QLP  + KKTKTGYSTAVDVLE+L    PI+  IL+YRQ++KLQSTYV
Sbjct  533  PKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYV  592

Query  590  EGLQKVISDDQRIHTRFNQTLAQTGRLSSVDPNLQNIPVRLEEGRKIRKAFKPTSKDSVI  649
             GLQ  I  D +IHTR+ Q L+QTGRLSSVDPNLQNIP+RLE+GR IRKAF P+  D+V+
Sbjct  593  IGLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVL  652

Query  650  LSADYSQIELRVLAHITQDESMKEAFINGDDIHTATAMKVFGVE-ADQVDSLMRRQAKAV  708
            LS+DYSQIELRVLAHI+ DE +  AF +G DIHT+TAM+VFG++ A +V +  RR+AKAV
Sbjct  653  LSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAV  712

Query  709  NFGIVYGISDYGLSQSLGITRKKAKAFIDDYLASFPGVKQYMSDIVKDAKALGYVETLLH  768
            NFGIVYGISD+GLS++LGITRK++K++ID Y+  +PG+K YM ++V++AK  GYVETL+ 
Sbjct  713  NFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFK  772

Query  769  RRRYIPDITSRNFNLRGFAERTAMNTPIQGSAADIIKLAMVKFAQKMKETTYQAKLLLQV  828
            RRR +PDI SRNFN+R+FAERTA+N+PIQGSAADI+K+AM+++ + ++   ++AK+LLQV
Sbjct  773  RRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQV  832

Query  829  HDELIFEVPKsevdsfsefveeIMENALQLDVPLKVDSSYGATWYDAK  876
            HDE+++EVP+ E+ ++  +V + ME A++L VPL VD S G +WY+AK
Sbjct  833  HDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

384) polA in NC_017331


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  675 bits (2554),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 426/888 (48%), Positives = 638/888 (72%), Gaps = 25/888 (2%)

Query  2    NKLVLIDGNSLSFRAFYAL----PLLSNKAGIHTNAVYGFAMLLEKILKEEKPNHFLVAF  57
            NKL+LIDG+S++FRAF+AL      + N +G+HTNA+YGF ++L+ ++K  +P H LVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  58   DAGKTTFRHEKYSEYKGGRQKTPPELSEQFPYIRQLLDAYHIKRYELDNYEADDIIGTLS  117
            DAGKTTFR E Y++YK+GR KTP E+ EQF+YIR++L A  I  YEL++YEADDIIGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  118  KEADKAG--FQTIIITGDRDLTQLATDNVTIYYTKKGVTDVDHYTPDFIAEKYNGLTPNQ  175
            K A+++   F+  I++GD+DL QL+ +N  +  +KKGV++ +++TP ++ EK  GLTPNQ
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEK-MGLTPNQ  183

Query  176  IIDMKGLMGDTSDNIPGVAGVGEKTAIKLLNQFDTVEGVYEHLDEISGKKLKEKLQNSKE  235
            +ID+K+LMGD SDNIPGV+ +GEKT++KLL++F+++EG+YEH+D +   K+KE+L N ++
Sbjct  184  FIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRD  243

Query  236  DALMSKELATINVDSPIEVKLEDTLMTHQDeqqekielfkklefkqllADIDQSASVEDA  295
            +A++SK LATIN  SPI + L+D +    D              +   + +    + E  
Sbjct  244  QAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKG-LASQMPQEPV  302

Query  296  IEKTFEIETSFDNIDFTSLKEAAIHFELDGGNYLRNNILKFSLFTGEKHIVINAD----D  351
               +++  T+     F++  E  + FE   +NY R+ I+ F+   GE +I  ++D     
Sbjct  303  AVISYQEVTNVSADLFSA--EDIFYFETLRDNYHREAIIGFAWGHGE-QIYASTDLSLLA  359

Query  352  INNYVELVSWLENPNSKKVVYDAKKTYVASHRLGIDIQNISFDIMLASYIIDPSRTISDV  411
             +++ ++   +++P +    YD K++ V   +LGI++   S+D  LA+Y++      +++
Sbjct  360  TDSFKQV---FQKPIA---TYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NEL  412

Query  412  QSVVSLYGQSFVKDDVSIYGKGKKFKVPEDDVLNPYVASITDAIYFAKPNMDKQLEEYNQ  471
             ++  ++ +  + +D ++YGKG K  VP+ DVL   +A     +  +K++M  +L   +Q
Sbjct  413  STIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQ  472

Query  472  VELLADLELPLAKILSEMEEIGIFTDVHDLEEMEKEIQEKLDVLIRNIHDAAGEDFNINS  531
            ++L  ++ELPLA++L+ ME  GI  +   L++M  + +  ++ L ++I D AG++FNINS
Sbjct  473  LDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINS  532

Query  532  PKQLGVVLFETLQLP--VIKKTKTGYSTAVDVLEQLQGEHPIIDYILEYRQLSKLQSTYV  589
            PKQLG +LFE +QLP  + KKTKTGYSTAVDVLE+L    PI+  IL+YRQ++KLQSTYV
Sbjct  533  PKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYV  592

Query  590  EGLQKVISDDQRIHTRFNQTLAQTGRLSSVDPNLQNIPVRLEEGRKIRKAFKPTSKDSVI  649
             GLQ  I  D +IHTR+ Q L+QTGRLSSVDPNLQNIP+RLE+GR IRKAF P+  D+V+
Sbjct  593  IGLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVL  652

Query  650  LSADYSQIELRVLAHITQDESMKEAFINGDDIHTATAMKVFGVE-ADQVDSLMRRQAKAV  708
            LS+DYSQIELRVLAHI+ DE +  AF +G DIHT+TAM+VFG++ A +V +  RR+AKAV
Sbjct  653  LSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAV  712

Query  709  NFGIVYGISDYGLSQSLGITRKKAKAFIDDYLASFPGVKQYMSDIVKDAKALGYVETLLH  768
            NFGIVYGISD+GLS++LGITRK++K++ID Y+  +PG+K YM ++V++AK  GYVETL+ 
Sbjct  713  NFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFK  772

Query  769  RRRYIPDITSRNFNLRGFAERTAMNTPIQGSAADIIKLAMVKFAQKMKETTYQAKLLLQV  828
            RRR +PDI SRNFN+R+FAERTA+N+PIQGSAADI+K+AM+++ + ++   ++AK+LLQV
Sbjct  773  RRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQV  832

Query  829  HDELIFEVPKsevdsfsefveeIMENALQLDVPLKVDSSYGATWYDAK  876
            HDE+++EVP+ E+ ++  +V + ME A++L VPL VD S G +WY+AK
Sbjct  833  HDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

385) polA in NC_007793


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  675 bits (2554),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 426/888 (48%), Positives = 638/888 (72%), Gaps = 25/888 (2%)

Query  2    NKLVLIDGNSLSFRAFYAL----PLLSNKAGIHTNAVYGFAMLLEKILKEEKPNHFLVAF  57
            NKL+LIDG+S++FRAF+AL      + N +G+HTNA+YGF ++L+ ++K  +P H LVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  58   DAGKTTFRHEKYSEYKGGRQKTPPELSEQFPYIRQLLDAYHIKRYELDNYEADDIIGTLS  117
            DAGKTTFR E Y++YK+GR KTP E+ EQF+YIR++L A  I  YEL++YEADDIIGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  118  KEADKAG--FQTIIITGDRDLTQLATDNVTIYYTKKGVTDVDHYTPDFIAEKYNGLTPNQ  175
            K A+++   F+  I++GD+DL QL+ +N  +  +KKGV++ +++TP ++ EK  GLTPNQ
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEK-MGLTPNQ  183

Query  176  IIDMKGLMGDTSDNIPGVAGVGEKTAIKLLNQFDTVEGVYEHLDEISGKKLKEKLQNSKE  235
            +ID+K+LMGD SDNIPGV+ +GEKT++KLL++F+++EG+YEH+D +   K+KE+L N ++
Sbjct  184  FIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRD  243

Query  236  DALMSKELATINVDSPIEVKLEDTLMTHQDeqqekielfkklefkqllADIDQSASVEDA  295
            +A++SK LATIN  SPI + L+D +    D              +   + +    + E  
Sbjct  244  QAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKG-LASQMPQEPV  302

Query  296  IEKTFEIETSFDNIDFTSLKEAAIHFELDGGNYLRNNILKFSLFTGEKHIVINAD----D  351
               +++  T+     F++  E  + FE   +NY R+ I+ F+   GE +I  ++D     
Sbjct  303  AVISYQEVTNVSADLFSA--EDIFYFETLRDNYHREAIIGFAWGHGE-QIYASTDLSLLA  359

Query  352  INNYVELVSWLENPNSKKVVYDAKKTYVASHRLGIDIQNISFDIMLASYIIDPSRTISDV  411
             +++ ++   +++P +    YD K++ V   +LGI++   S+D  LA+Y++      +++
Sbjct  360  TDSFKQV---FQKPIA---TYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NEL  412

Query  412  QSVVSLYGQSFVKDDVSIYGKGKKFKVPEDDVLNPYVASITDAIYFAKPNMDKQLEEYNQ  471
             ++  ++ +  + +D ++YGKG K  VP+ DVL   +A     +  +K++M  +L   +Q
Sbjct  413  STIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQ  472

Query  472  VELLADLELPLAKILSEMEEIGIFTDVHDLEEMEKEIQEKLDVLIRNIHDAAGEDFNINS  531
            ++L  ++ELPLA++L+ ME  GI  +   L++M  + +  ++ L ++I D AG++FNINS
Sbjct  473  LDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINS  532

Query  532  PKQLGVVLFETLQLP--VIKKTKTGYSTAVDVLEQLQGEHPIIDYILEYRQLSKLQSTYV  589
            PKQLG +LFE +QLP  + KKTKTGYSTAVDVLE+L    PI+  IL+YRQ++KLQSTYV
Sbjct  533  PKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYV  592

Query  590  EGLQKVISDDQRIHTRFNQTLAQTGRLSSVDPNLQNIPVRLEEGRKIRKAFKPTSKDSVI  649
             GLQ  I  D +IHTR+ Q L+QTGRLSSVDPNLQNIP+RLE+GR IRKAF P+  D+V+
Sbjct  593  IGLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVL  652

Query  650  LSADYSQIELRVLAHITQDESMKEAFINGDDIHTATAMKVFGVE-ADQVDSLMRRQAKAV  708
            LS+DYSQIELRVLAHI+ DE +  AF +G DIHT+TAM+VFG++ A +V +  RR+AKAV
Sbjct  653  LSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAV  712

Query  709  NFGIVYGISDYGLSQSLGITRKKAKAFIDDYLASFPGVKQYMSDIVKDAKALGYVETLLH  768
            NFGIVYGISD+GLS++LGITRK++K++ID Y+  +PG+K YM ++V++AK  GYVETL+ 
Sbjct  713  NFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFK  772

Query  769  RRRYIPDITSRNFNLRGFAERTAMNTPIQGSAADIIKLAMVKFAQKMKETTYQAKLLLQV  828
            RRR +PDI SRNFN+R+FAERTA+N+PIQGSAADI+K+AM+++ + ++   ++AK+LLQV
Sbjct  773  RRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQV  832

Query  829  HDELIFEVPKsevdsfsefveeIMENALQLDVPLKVDSSYGATWYDAK  876
            HDE+++EVP+ E+ ++  +V + ME A++L VPL VD S G +WY+AK
Sbjct  833  HDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

386) polA in NC_010079


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  675 bits (2554),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 426/888 (48%), Positives = 638/888 (72%), Gaps = 25/888 (2%)

Query  2    NKLVLIDGNSLSFRAFYAL----PLLSNKAGIHTNAVYGFAMLLEKILKEEKPNHFLVAF  57
            NKL+LIDG+S++FRAF+AL      + N +G+HTNA+YGF ++L+ ++K  +P H LVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  58   DAGKTTFRHEKYSEYKGGRQKTPPELSEQFPYIRQLLDAYHIKRYELDNYEADDIIGTLS  117
            DAGKTTFR E Y++YK+GR KTP E+ EQF+YIR++L A  I  YEL++YEADDIIGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  118  KEADKAG--FQTIIITGDRDLTQLATDNVTIYYTKKGVTDVDHYTPDFIAEKYNGLTPNQ  175
            K A+++   F+  I++GD+DL QL+ +N  +  +KKGV++ +++TP ++ EK  GLTPNQ
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEK-MGLTPNQ  183

Query  176  IIDMKGLMGDTSDNIPGVAGVGEKTAIKLLNQFDTVEGVYEHLDEISGKKLKEKLQNSKE  235
            +ID+K+LMGD SDNIPGV+ +GEKT++KLL++F+++EG+YEH+D +   K+KE+L N ++
Sbjct  184  FIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRD  243

Query  236  DALMSKELATINVDSPIEVKLEDTLMTHQDeqqekielfkklefkqllADIDQSASVEDA  295
            +A++SK LATIN  SPI + L+D +    D              +   + +    + E  
Sbjct  244  QAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKG-LASQMPQEPV  302

Query  296  IEKTFEIETSFDNIDFTSLKEAAIHFELDGGNYLRNNILKFSLFTGEKHIVINAD----D  351
               +++  T+     F++  E  + FE   +NY R+ I+ F+   GE +I  ++D     
Sbjct  303  AVISYQEVTNVSADLFSA--EDIFYFETLRDNYHREAIIGFAWGHGE-QIYASTDLSLLA  359

Query  352  INNYVELVSWLENPNSKKVVYDAKKTYVASHRLGIDIQNISFDIMLASYIIDPSRTISDV  411
             +++ ++   +++P +    YD K++ V   +LGI++   S+D  LA+Y++      +++
Sbjct  360  TDSFKQV---FQKPIA---TYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NEL  412

Query  412  QSVVSLYGQSFVKDDVSIYGKGKKFKVPEDDVLNPYVASITDAIYFAKPNMDKQLEEYNQ  471
             ++  ++ +  + +D ++YGKG K  VP+ DVL   +A     +  +K++M  +L   +Q
Sbjct  413  STIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQ  472

Query  472  VELLADLELPLAKILSEMEEIGIFTDVHDLEEMEKEIQEKLDVLIRNIHDAAGEDFNINS  531
            ++L  ++ELPLA++L+ ME  GI  +   L++M  + +  ++ L ++I D AG++FNINS
Sbjct  473  LDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINS  532

Query  532  PKQLGVVLFETLQLP--VIKKTKTGYSTAVDVLEQLQGEHPIIDYILEYRQLSKLQSTYV  589
            PKQLG +LFE +QLP  + KKTKTGYSTAVDVLE+L    PI+  IL+YRQ++KLQSTYV
Sbjct  533  PKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYV  592

Query  590  EGLQKVISDDQRIHTRFNQTLAQTGRLSSVDPNLQNIPVRLEEGRKIRKAFKPTSKDSVI  649
             GLQ  I  D +IHTR+ Q L+QTGRLSSVDPNLQNIP+RLE+GR IRKAF P+  D+V+
Sbjct  593  IGLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVL  652

Query  650  LSADYSQIELRVLAHITQDESMKEAFINGDDIHTATAMKVFGVE-ADQVDSLMRRQAKAV  708
            LS+DYSQIELRVLAHI+ DE +  AF +G DIHT+TAM+VFG++ A +V +  RR+AKAV
Sbjct  653  LSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAV  712

Query  709  NFGIVYGISDYGLSQSLGITRKKAKAFIDDYLASFPGVKQYMSDIVKDAKALGYVETLLH  768
            NFGIVYGISD+GLS++LGITRK++K++ID Y+  +PG+K YM ++V++AK  GYVETL+ 
Sbjct  713  NFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFK  772

Query  769  RRRYIPDITSRNFNLRGFAERTAMNTPIQGSAADIIKLAMVKFAQKMKETTYQAKLLLQV  828
            RRR +PDI SRNFN+R+FAERTA+N+PIQGSAADI+K+AM+++ + ++   ++AK+LLQV
Sbjct  773  RRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQV  832

Query  829  HDELIFEVPKsevdsfsefveeIMENALQLDVPLKVDSSYGATWYDAK  876
            HDE+++EVP+ E+ ++  +V + ME A++L VPL VD S G +WY+AK
Sbjct  833  HDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

387) SAVC_07655 in NC_016912


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  675 bits (2554),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 426/888 (48%), Positives = 638/888 (72%), Gaps = 25/888 (2%)

Query  2    NKLVLIDGNSLSFRAFYAL----PLLSNKAGIHTNAVYGFAMLLEKILKEEKPNHFLVAF  57
            NKL+LIDG+S++FRAF+AL      + N +G+HTNA+YGF ++L+ ++K  +P H LVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  58   DAGKTTFRHEKYSEYKGGRQKTPPELSEQFPYIRQLLDAYHIKRYELDNYEADDIIGTLS  117
            DAGKTTFR E Y++YK+GR KTP E+ EQF+YIR++L A  I  YEL++YEADDIIGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  118  KEADKAG--FQTIIITGDRDLTQLATDNVTIYYTKKGVTDVDHYTPDFIAEKYNGLTPNQ  175
            K A+++   F+  I++GD+DL QL+ +N  +  +KKGV++ +++TP ++ EK  GLTPNQ
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEK-MGLTPNQ  183

Query  176  IIDMKGLMGDTSDNIPGVAGVGEKTAIKLLNQFDTVEGVYEHLDEISGKKLKEKLQNSKE  235
            +ID+K+LMGD SDNIPGV+ +GEKT++KLL++F+++EG+YEH+D +   K+KE+L N ++
Sbjct  184  FIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRD  243

Query  236  DALMSKELATINVDSPIEVKLEDTLMTHQDeqqekielfkklefkqllADIDQSASVEDA  295
            +A++SK LATIN  SPI + L+D +    D              +   + +    + E  
Sbjct  244  QAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKG-LASQMPQEPV  302

Query  296  IEKTFEIETSFDNIDFTSLKEAAIHFELDGGNYLRNNILKFSLFTGEKHIVINAD----D  351
               +++  T+     F++  E  + FE   +NY R+ I+ F+   GE +I  ++D     
Sbjct  303  AVISYQEVTNVSADLFSA--EDIFYFETLRDNYHREAIIGFAWGHGE-QIYASTDLSLLA  359

Query  352  INNYVELVSWLENPNSKKVVYDAKKTYVASHRLGIDIQNISFDIMLASYIIDPSRTISDV  411
             +++ ++   +++P +    YD K++ V   +LGI++   S+D  LA+Y++      +++
Sbjct  360  TDSFKQV---FQKPIA---TYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NEL  412

Query  412  QSVVSLYGQSFVKDDVSIYGKGKKFKVPEDDVLNPYVASITDAIYFAKPNMDKQLEEYNQ  471
             ++  ++ +  + +D ++YGKG K  VP+ DVL   +A     +  +K++M  +L   +Q
Sbjct  413  STIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQ  472

Query  472  VELLADLELPLAKILSEMEEIGIFTDVHDLEEMEKEIQEKLDVLIRNIHDAAGEDFNINS  531
            ++L  ++ELPLA++L+ ME  GI  +   L++M  + +  ++ L ++I D AG++FNINS
Sbjct  473  LDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINS  532

Query  532  PKQLGVVLFETLQLP--VIKKTKTGYSTAVDVLEQLQGEHPIIDYILEYRQLSKLQSTYV  589
            PKQLG +LFE +QLP  + KKTKTGYSTAVDVLE+L    PI+  IL+YRQ++KLQSTYV
Sbjct  533  PKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYV  592

Query  590  EGLQKVISDDQRIHTRFNQTLAQTGRLSSVDPNLQNIPVRLEEGRKIRKAFKPTSKDSVI  649
             GLQ  I  D +IHTR+ Q L+QTGRLSSVDPNLQNIP+RLE+GR IRKAF P+  D+V+
Sbjct  593  IGLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVL  652

Query  650  LSADYSQIELRVLAHITQDESMKEAFINGDDIHTATAMKVFGVE-ADQVDSLMRRQAKAV  708
            LS+DYSQIELRVLAHI+ DE +  AF +G DIHT+TAM+VFG++ A +V +  RR+AKAV
Sbjct  653  LSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAV  712

Query  709  NFGIVYGISDYGLSQSLGITRKKAKAFIDDYLASFPGVKQYMSDIVKDAKALGYVETLLH  768
            NFGIVYGISD+GLS++LGITRK++K++ID Y+  +PG+K YM ++V++AK  GYVETL+ 
Sbjct  713  NFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFK  772

Query  769  RRRYIPDITSRNFNLRGFAERTAMNTPIQGSAADIIKLAMVKFAQKMKETTYQAKLLLQV  828
            RRR +PDI SRNFN+R+FAERTA+N+PIQGSAADI+K+AM+++ + ++   ++AK+LLQV
Sbjct  773  RRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQV  832

Query  829  HDELIFEVPKsevdsfsefveeIMENALQLDVPLKVDSSYGATWYDAK  876
            HDE+++EVP+ E+ ++  +V + ME A++L VPL VD S G +WY+AK
Sbjct  833  HDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

388) SAPIG1744 in NC_017333


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  674 bits (2548),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 427/888 (49%), Positives = 638/888 (72%), Gaps = 25/888 (2%)

Query  2    NKLVLIDGNSLSFRAFYAL----PLLSNKAGIHTNAVYGFAMLLEKILKEEKPNHFLVAF  57
            NKL+LIDG+S++FRAF+AL      + N +G+HTNA+YGF ++L+ ++K  +P H LVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  58   DAGKTTFRHEKYSEYKGGRQKTPPELSEQFPYIRQLLDAYHIKRYELDNYEADDIIGTLS  117
            DAGKTTFR E Y++YK+GR KTP E+ EQF+YIR++L A  I  YEL++YEADDIIGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  118  KEADKAG--FQTIIITGDRDLTQLATDNVTIYYTKKGVTDVDHYTPDFIAEKYNGLTPNQ  175
            K A+++   F+  I++GD+DL QL+ +N  +  +KKGV++ +++TP ++ EK  GLTPNQ
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEK-MGLTPNQ  183

Query  176  IIDMKGLMGDTSDNIPGVAGVGEKTAIKLLNQFDTVEGVYEHLDEISGKKLKEKLQNSKE  235
            +ID+K+LMGD SDNIPGV+ +GEKT++KLL++F+++EG+YEH+D +   K+KE+L N ++
Sbjct  184  FIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRD  243

Query  236  DALMSKELATINVDSPIEVKLEDTLMTHQDeqqekielfkklefkqllADIDQSASGEDA  295
            +A++SK LATIN  SPI + L+D +    D              +   +   Q +    A
Sbjct  244  QAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEPVA  303

Query  296  IEKTFEIETSFDNVDFTSLEEAAIHFELDGGNYLRNNILKFSLFTGEKHIVINAD----D  351
            +  +++  T+     F++  E  + FE   +NY R+ I+ F+   GE +I  ++D     
Sbjct  304  V-ISYQEVTNVSADLFSA--EDIFYFETLRDNYHREAIIGFAWGHGE-QIYASTDLSLLA  359

Query  352  INNYAELVSWLENPNTKKVVYDAKKTYVASHRLGIDIQNISFDIMLASYIIDPSRTISDV  411
             +++ ++   +++P +    YD K++ V   +LGI++   S+D  LA+Y++      +++
Sbjct  360  TDSFKQV---FQKPIA---TYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NEL  412

Query  412  QSVVSLYGQSFVKDDVSIYGKGKKFKVPEDDVLNPYVAFITDAIYFAKPNMDKQLEEYNQ  471
             ++  ++ +  + +D ++YGKG K  VP+ DVL   +A     +  +K++M  +L   +Q
Sbjct  413  STIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQ  472

Query  472  VELLADLELPLAKILSEMEEIGIYTDVHDLEEMEKEIQEKLDVLIRNIHDAAGEDFNINS  531
            ++L  ++ELPLA++L+ ME  GI  +   L++M  + +  ++ L ++I D AG++FNINS
Sbjct  473  LDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINS  532

Query  532  PKQLGVVLFETLQLP--VIKKTKTGYSTAVDVLEQLQGEHPIIDYILEYRQLSKLQSTYV  589
            PKQLG +LFE +QLP  + KKTKTGYSTAVDVLE+L    PI+  IL+YRQ++KLQSTYV
Sbjct  533  PKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYV  592

Query  590  EGLQKVISDDQRIHTRFNQTLAQTGRLSSVDPNLQNIPVRLEEGRKIRKAFKPTSKDSVI  649
             GLQ  I  D +IHTR+ Q L+QTGRLSSVDPNLQNIP+RLE+GR IRKAF P+  D+V+
Sbjct  593  IGLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVL  652

Query  650  LSADYSQIELRVLAHITQDESMKEAFINGDDIHTATAMKVFGVE-ADQVDSLMRRQAKAV  708
            LS+DYSQIELRVLAHI+ DE +  AF +G DIHT+TAM+VFG++ A +V +  RR+AKAV
Sbjct  653  LSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAV  712

Query  709  NFGIVYGISDYGLSQSLGITRKKAKVFIDDYLASFPGVKQYMSDIVKDAKALGYVETLLH  768
            NFGIVYGISD+GLS++LGITRK++K +ID Y+  +PG+K YM ++V++AK  GYVETL+ 
Sbjct  713  NFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFK  772

Query  769  RRRYIPDITSRNFNLRGFAERTAMNTPIQGSAADIIKLAMVKFAQKMKETTYQAKLLLQV  828
            RRR +PDI SRNFN+R+FAERTA+N+PIQGSAADI+K+AM+++ + ++   ++AK+LLQV
Sbjct  773  RRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQV  832

Query  829  HDELIFEVPKsevdsfsefveeIMENALQLDVPLKVDSSYGATWYDAK  876
            HDE+++EVP+ E+ ++  +V + ME A++L VPL VD S G +WY+AK
Sbjct  833  HDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

389) SAA6159_01614 in NC_017338


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  674 bits (2547),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 425/888 (48%), Positives = 637/888 (72%), Gaps = 25/888 (2%)

Query  2    NKLVLIDGNSLSFRAFYAL----PLLSNKAGIHTNAVYGFAMLLEKILKEEKPNHFLVAF  57
            NKL+LIDG+S++FRAF+AL      + N +G+HTNA+YGF ++L+ ++K  +P H LVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  58   DAGKTTFRHEKYSEYKGGRQKTPPELSEQFPYIRQLLDAYHIKRYELDNYEADDIIGTLS  117
            DAGKTTFR E Y++YK+GR KTP E+ EQF+YIR++L A  I  YEL++YEADDIIGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  118  KEADKAG--FQTIIITGDRDLTQLATDNVTIYYTKKGVTDVDHYTPDFIAEKYNGLTPNQ  175
            K A+++   F+  I++GD+DL QL+ +N  +  +KKGV++ +++TP ++ EK  GLTPNQ
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEK-MGLTPNQ  183

Query  176  IIDMKGLMGDTSDNIPGVAGVGEKTAIKLLNQFDTVEGVYEHLDEISGKKLKEKLQNSKE  235
            +ID+K+LMGD SDNIPGV+ +GEKT++KLL++F+++EG+YEH+D +   K+KE+L N ++
Sbjct  184  FIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRD  243

Query  236  DALMSKELATINVDSPIEVKLEDTLMTHQDeqqekielfkklefkqllADIDQSASVEDA  295
            +A++SK LATIN  SPI + L+D +    D              +   + +    + E  
Sbjct  244  QAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKG-LASQMPQEPV  302

Query  296  IEKTFEIETSFDNIDFTSLKEAAIHFELDGGNYLRNNILKFSLFTGEKHIVINAD----D  351
               +++  T+     F++  E  + FE   +NY R+ I+ F+   GE +I  ++D     
Sbjct  303  AVISYQEVTNVSADLFSA--EDIFYFETLRDNYHREAIIGFAWGHGE-QIYASTDLSLLA  359

Query  352  INNYVELVSWLENPNTKKVVYDAKKTYVASHRLEIDIQNISFDIMLASYIIDPSRTISDV  411
             +++ ++   +++P +    YD K++ V   +L I++   S+D  LA+Y++      +++
Sbjct  360  TDSFKQV---FQKPIA---TYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NEL  412

Query  412  QSVVSLYGQSFVKDDVSIYGKGKKFKVPEDDVLNPYVASITDAIYFAKPNMDKQLEEYNQ  471
             ++  ++ +  + +D ++YGKG K  VP+ DVL   +A     +  +K++M  +L   +Q
Sbjct  413  STIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQ  472

Query  472  VELLADLELPLAKILSEMEEIGIYTDVHDLEEMEKEIQEKLDVLIRNIHDAAGEDFNINS  531
            ++L  ++ELPLA++L+ ME  GI  +   L++M  + +  ++ L ++I D AG++FNINS
Sbjct  473  LDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINS  532

Query  532  PKQLGVVLFETLQLP--VIKKTKTGYSTAVDVLEQLQGEHPIIDYILEYRQLSKLQSTYV  589
            PKQLG +LFE +QLP  + KKTKTGYSTAVDVLE+L    PI+  IL+YRQ++KLQSTYV
Sbjct  533  PKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYV  592

Query  590  EGLQKVISDDQRIHTRFNQTLAQTGRLSSVDPNLQNIPVRLEEGRKIRKAFKPTSKDSVI  649
             GLQ  I  D +IHTR+ Q L+QTGRLSSVDPNLQNIP+RLE+GR IRKAF P+  D+V+
Sbjct  593  IGLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVL  652

Query  650  LSADYSQIELRVLAHITQDESMKEAFINGDDIHTATAMKVFGVE-ADQVDSLMRRQAKAV  708
            LS+DYSQIELRVLAHI+ DE +  AF +G DIHT+TAM+VFG++ A +V +  RR+AKAV
Sbjct  653  LSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAV  712

Query  709  NFGIVYGISDYGLSQSLGITRKKAKAFIDDYLASFPGVKQYMSDIVKDAKALGYVETLLH  768
            NFGIVYGISD+GLS++LGITRK++K++ID Y+  +PG+K YM ++V++AK  GYVETL+ 
Sbjct  713  NFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFK  772

Query  769  RRRYIPDITSRNFNLRGFAERTAMNTPIQGSAADIIKLAMVKFAQKMKETTYQAKLLLQV  828
            RRR +PDI SRNFN+R+FAERTA+N+PIQGSAADI+K+AM+++ + ++   ++AK+LLQV
Sbjct  773  RRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQV  832

Query  829  HDELIFEVPKsevdsfsefveeIMENALQLDVPLKVDSSYGATWYDAK  876
            HDE+++EVP+ E+ ++  +V + ME A++L VPL VD S G +WY+AK
Sbjct  833  HDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

390) polA in NC_017342


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  674 bits (2550),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 423/884 (48%), Positives = 633/884 (72%), Gaps = 17/884 (1%)

Query  2    NKLVLIDGNSLSFRAFYAL----PLLSNKAGIHTNAVYGFAMLLEKILKEEKPNHFLVAF  57
            NKL+LIDG+S++FRAF+AL      + N +G+HTNA+YGF ++L+ ++K  +P H LVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  58   DAGKTTFRHEKYSEYKGGRQKTPPELSEQFPYIRQLLDAYHIKRYELDNYEADDIIGTLS  117
            DAGKTTFR E Y++YK+GR KTP E+ EQF+YIR++L A  I  YEL++YEADDIIGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  118  KEADKAG--FQTIIITGDRDLTQLATDNVTIYYTKKGVTDVDHYTPDFIAEKYNGLTPNQ  175
            K A+++   F+  I++GD+DL QL+ +N  +  +KKGV++ +++TP ++ EK  GLTPNQ
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEK-MGLTPNQ  183

Query  176  IIDMKGLMGDTSDNIPGVAGVGEKTAIKLLNQFDTVEGVYEHLDEISGKKLKEKLQNSKE  235
            +ID+K+LMGD SDNIPGV+ +GEKT++KLL++F+++EG+YEH+D +   K+KE+L N ++
Sbjct  184  FIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRD  243

Query  236  DALMSKELATINVDSPIEVKLEDTLMTHQDeqqekielfkklefkqllADIDQSASGEDA  295
            +A++SK LATIN  SPI + L+D +    D              +   +   Q +    A
Sbjct  244  QAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEPVA  303

Query  296  IEKTFEIETSFDNVDFTSLKEATIHFELDGGNYLRNNILKFSLFTGEKHIVINADDIINY  355
            +  +++  T+     F++  E  + FE   +NY R+ I+ F+   GE+        ++  
Sbjct  304  V-ISYQEVTNVSADLFSA--EDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLAT  360

Query  356  AELVSWLENPNTKKVVYDAKKTYVASHRLGIDIQNISFDIMLASYIIDPSRTISDVQSVV  415
              +   +++P +    YD K++ V   +LGI++   S+D  LA+Y++      +++ ++ 
Sbjct  361  DSFKQVFQKPIA---TYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NELSTIA  416

Query  416  SLYGQSFVKDDVSIYGKGKKFKVPEDDVLNPYVASITDAIYFAKPNMDKQLEEYNQVELL  475
             ++ +  + +D ++YGKG K  VP+ DVL   +A     +  +K++M  +L   +Q++L 
Sbjct  417  RIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLY  476

Query  476  ADLELSLAKILSEMEEIGIYTDVHDLEEMEKEIQEKLDVLIRNIHDAAGEDFNINSPKQL  535
             ++EL+LA++L+ ME  GI  +   L++M  + +  ++ L ++I D AG++FNINSPKQL
Sbjct  477  QNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQL  536

Query  536  GVVLFETLQLP--VIKKTKTGYSTAVDVLEQLQGEHPIIDYILEYRQLSKLQSTYVEGLQ  593
            G +LFE +QLP  + KKTKTGYSTAVDVLE+L    PI+  IL+YRQ++KLQSTYV GLQ
Sbjct  537  GSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQ  596

Query  594  KVISDDQRIHTRFNQTLAQTGRLSSVDPNLQNIPVRLEEGRKIRKAFKPTSKDSVILSAD  653
              I  D +IHTR+ Q L+QTGRLSSVDPNLQNIP+RLE+GR IRKAF P+  D+V+LS+D
Sbjct  597  DYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSD  656

Query  654  YSQIELRVLAHITQDESMKEAFINGDDIHTATAMKVFGVE-ADQVDSLMRRQAKAVNFGI  712
            YSQIELRVLAHI+ DE +  AF +G DIHT+TAM+VFG++ A +V +  RR+AKAVNFGI
Sbjct  657  YSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGI  716

Query  713  VYGISDYGLSQSLGITRKKAKAFIDDYLASFPGVKQYMSDIVKDAKALGFVETLLHRRRY  772
            VYGISD+GLS++LGITRK++K++ID Y+  +PG+K YM ++V++AK  G+VETL+ RRR 
Sbjct  717  VYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRE  776

Query  773  IPDITSRNFNLRGFAERTAMNTPIQGSAADIIKLAMVKFAQKMKETTYQAKLLLQVHDEL  832
            +PDI SRNFN+R+FAERTA+N+PIQGSAADI+K+AM+++ + ++   ++AK+LLQVHDE+
Sbjct  777  LPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEI  836

Query  833  IFEVPKsevdsfsefveeIMENALQLDVPLKVDSSYGATWYDAK  876
            ++EVP+ E+ ++  +V + ME A++L VPL VD S G +WY+AK
Sbjct  837  VLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

391) SAKOR_01630 in NC_022226


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  673 bits (2545),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 426/888 (48%), Positives = 637/888 (72%), Gaps = 25/888 (2%)

Query  2    NKLVLIDGNSLSFRAFYAL----PLLSNKAGIHTNAVYGFAMLLEKILKEEKPNHFLVAF  57
            NKL+LIDG+S++FRAF+AL      + N +G+HTNA+YGF ++L+ ++K  +P H LVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  58   DAGKTTFRHEKYSEYKGGRQKTPPELSEQFPYIRQLLDAYHIKRYELDNYEADDIIGTLS  117
            DAGKTTFR E Y++YK+GR KTP E+ EQF+YIR++L A  I  YEL++YEADDIIGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  118  KEADIAG--FQTIIITGDRDLTQLATDNVTIYYTKKGVTDVDHYTPDFIAEKYNGLTPNQ  175
            K A+ +   F+  I++GD+DL QL+ +N  +  +KKGV++ +++TP ++ EK  GLTPNQ
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEK-MGLTPNQ  183

Query  176  IIDMKGLMGDTSDNIPGVAGVGEKTAIKLLNQFDTVEGVYEHLDEISGKKLKEKLQNSKE  235
            +ID+K+LMGD SDNIPGV+ +GEKT++KLL++F+++EG+YEH+D +   K+KE+L N ++
Sbjct  184  FIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRD  243

Query  236  DALMSKELATINVDSPIEVKLEDTLMTHQDeqqekielfkklefkqllADIDQSASVEDA  295
            +A++SK LATIN  SPI + L+D +    D              +   + +    + E  
Sbjct  244  QAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKG-LASQMPQEPV  302

Query  296  IEKTFEIETSFDNIDFTSLKEAAIHFELDGGNYLRNNILKFSLFTGEKHIVINAD----D  351
               +++  T+     F++  E  + FE   +NY R+ I+ F+   GE +I  ++D     
Sbjct  303  AVISYQEVTNVSADLFSA--EDIFYFETLRDNYHREAIIGFAWGHGE-QIYASTDLSLLA  359

Query  352  INNYVELVSWLENPNSKKVVYDAKKTYVASHRLGIDIQNISFDIMLASYIIDPSRTISDV  411
             +++ ++   +++P +    YD K++ V   +LGI++   S+D  LA+Y++      +++
Sbjct  360  TDSFKQV---FQKPIA---TYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NEL  412

Query  412  QSVVSLYGQSFVKDDVSIYGKGKKFKVPEDDVLNPYVASITDAIYFAKPNMDKQLEEYNQ  471
             ++  ++ +  + +D ++YGKG K  VP+ DVL   +A     +  +K++M  +L   +Q
Sbjct  413  STIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQ  472

Query  472  VELLADLELPLAKILSEMEEIGIFTDVHDLEEMEKEIQEKLDVLIRNIHDAAGEDFNINS  531
            ++L  ++ELPLA++L+ ME  GI  +   L++M  + +  ++ L ++I D AG++FNINS
Sbjct  473  LDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINS  532

Query  532  PKQLGVVLFETLQLP--VIKKTKTGYSTAVDVLEQLQGEHPIIDYILEYRQLSKLQSTYV  589
            PKQLG +LFE +QLP  + KKTKTGYSTAVDVLE+L    PI+  IL+YRQ++KLQSTYV
Sbjct  533  PKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYV  592

Query  590  EGLQKVISDDQRIHTRFNQTLAQTGRLSSVDPNLQNIPVRLEEGRKIRKAFKPTSKDSVI  649
             GLQ  I  D +IHTR+ Q L+QTGRLSSVDPNLQNIP+RLE+GR IRKAF P+  D+V+
Sbjct  593  IGLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVL  652

Query  650  LSADYSQIELRVLAHITQDESMKEAFINGDDIHTATAMKVFGVE-ADQVDSLMRRQAKAV  708
            LS+DYSQIELRVLAHI+ DE +  AF +G DIHT+TAM+VFG++ A +V +  RR+AKAV
Sbjct  653  LSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAV  712

Query  709  NFGIVYGISDYGLSQSLGITRKKAKAFIDDYLASFPGVKQYMSDIVKDAKALGYVETLLH  768
            NFGIVYGISD+GLS++LGITRK++K++ID Y+  +PG+K YM ++V++AK  GYVETL+ 
Sbjct  713  NFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFK  772

Query  769  RRRYIPDITSRNFNLRGFAERTAMNTPIQGSAADIIKLAMVKFAQKMKETTYQAKLLLQV  828
            RRR +PDI SRNFN+R+FAERTA+N+PIQGSAADI+K+AM+++ + ++   ++AK+LLQV
Sbjct  773  RRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQV  832

Query  829  HDELIFEVPKsevdsfsefveeIMENALQLDVPLKVDSSYGATWYDAK  876
            HDE+++EVP+ E+ ++  +V + ME A++L VPL VD S G +WY+AK
Sbjct  833  HDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

392) polA in NC_016011


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  672 bits (2539),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 440/885 (50%), Positives = 640/885 (73%), Gaps = 20/885 (2%)

Query  2    NKLVLIDGNSIANRAFYAL----PLLNNDKGVYTNAVYGFAMMLMNVLEKEKPSHVLVAF  57
            NKL+LIDG+S+A RAF+AL      ++N+ G+ TNA+YGF +ML +++ + +P+HVLVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  58   DAGKTTFRHATFKGYKGGRQKTPSELSEQFPFIRELLTAYDIPQYELANYEADDIIGTLT  117
            DAGKTTFR   + +YK+GR KTP E+ EQF++IRE+LTA +I+ YEL +YEADDIIGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  118  KKAEADGL--EVAIITGDRDLTQLASNKTTVYITKKGIADMETNTPETLKEKYNLTPAQI  175
            K AE   +  +V+I++GD+DL QL+ ++T V I+KKG+A+ E  TP  L EK  LTP Q+
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  176  IDMKGLMGDSSDNIPGIPGVGEKTALKLLHEFGGSVESVLEHADEISGkklkekvlenke  235
            ID+K+LMGD SDNIPG+  +GEKT+LKLLHEFG S+E++ EH D +   K+KE+++++++
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFG-SLEGIYEHIDGFKTSKMKENLINDRD  243

Query  236  lAILSKELATINVDSPIEYTIENTKYNGYQTDKVIPLLKEMQFTTLLKNMEGDTPGETKE  295
             A+LSK LATIN  SPI   +++  YNG +   +  +  EM+F  L K + ++ P E   
Sbjct  244  QAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEPVA  303

Query  296  LKELTFEVVTDLTEKHFGGKTALYVELENDNYHTANFIGLTVHSSNGTYFFTKETAENSS  355
            +  ++++ VT+++   F++   +Y E   DNYH   +IG++   ++  Y  T  +   + 
Sbjct  304  V--ISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLATD  361

Query  356  AFKTWVESGAAKVVYDAKKTMVAMHRLGYAISGITFDIMLASYLLNPSDSIGDFTSVAVR  415
            +FK   +   A   YD K++ V + +LG  + + ++D  LA+YLL+  +   +++++A  
Sbjct  362  SFKQVFQKPIA--TYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NELSTIA--  416

Query  416  HDYTEV--ETDEAIYGKGAKRSTPEESIVAPHLARKAVAVAVLEKGLIDDLEKNEQLALM  473
            + +T++  E D+++YGKGAKR+ P+  ++  HLARK   +      ++D L  +EQL L 
Sbjct  417  RIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLY  476

Query  474  EDLELPLTFVLAQMEIQGVSVDTKRLEGMKVELASRLKTLEESIHSLAGEDFNINSPKQL  533
            +++ELPL+ VLA+MEI+G+ V+   L++M  +    + +L + I  +AG++FNINSPKQL
Sbjct  477  QNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQL  536

Query  534  GVILFEKLGLP--AVKKTKTGYSTAADVLESLSGSHDIIDEILLYRQLGKIQSTYIEGLL  591
            G ILFEK+ LP    KKTKTGYSTA DVLE L+    I+  IL YRQ+ K+QSTY+ GL 
Sbjct  537  GSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQ  596

Query  592  KVTDKETHKVHTRFNQTLTQTGRLSSVDPNLQNIPIRLEEGRKIRQVFVPSQPGWKIFSA  651
                 +  K+HTR+ Q LTQTGRLSSVDPNLQNIPIRLE+GR IR+ F PS+ +  ++S+
Sbjct  597  DYILADG-KIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSS  655

Query  652  DYSQVELRVLAHISEDENLIYAFKHDYDIHTKTAMDVFHVEKE-EVDSLMRRQAKAVNFG  710
            DYSQ+ELRVLAHIS DE+LI AF+++ DIHT TAM VF ++K  +V +  RR+AKAVNFG
Sbjct  656  DYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFG  715

Query  711  IVYGISDYGLSQNLGITRKEAKDFIDRYFVSYPAVKEYMQDIVRFAKEKGYVETILHRRR  770
            IVYGISD+GLS+NLGITRK++K +ID YF  YP++K YM+++VR AK+KGYVET++ RRR
Sbjct  716  IVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRR  775

Query  771  YIPEIVSRNFNVRGFAERTAMNTPIQGSAADIIKKAMILMNDRlesekleaklllQVHDE  830
             +P+I SRNFNVR+FAERTA+N+PIQGSAADI+K AMI ++  L++  + AK+LLQVHDE
Sbjct  776  ELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDE  835

Query  831  LIFEAPEAEIAKLEEIVPDVMENAVELSVPLKVDSAFGDTWYDAK  875
            +++E P+ E++ +  +V D ME AV+L+VPL VD + G++WY+AK
Sbjct  836  IVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

393) polA in NC_013891


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  672 bits (2541),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 440/885 (50%), Positives = 643/885 (73%), Gaps = 20/885 (2%)

Query  2    NKLVLIDGNSIANRAFYAL----PLLNNDKGVYTNAVYGFAMMLMNVLEKEKPSHVLVAF  57
            NKL+LIDG+S+A RAF+AL      ++N+ G+ TNA+YGF +ML +++ + +P+HVLVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  58   DAGKTTFRHATFKGYKGGRQKTPSELSEQFPFIRELLAAYDIPQYELANYEADDIIGTLT  117
            DAGKTTFR   + +YK+GR KTP E+ EQF++IRE+L+A +I+ YEL +YEADDIIGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  118  KKAEADGL--EVAIITGDRDLTQLASDKTTVYITKKGIADMETNTPETLKEKYNLTPAQI  175
            K AE   +  +V+I++GD+DL QL+ ++T V I+KKG+A+ E  TP  L EK  LTP Q+
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  176  IDMKGLMGDSSDNIPGIPGVGEKTALKLLHEFGGSVESVLEHADEISGkklkekvlenke  235
            ID+K+LMGD SDNIPG+  +GEKT+LKLLHEFG S+E++ EH D +   K+KE+++++++
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFG-SLEGIYEHIDGFKTSKMKENLINDRD  243

Query  236  lAILSKELATINVESPIECTIESTKYDGYQTEKVIPLLKEMQFTTLLKNIEGDTPEEAKE  295
             A+LSK LATIN  SPI   ++   Y+G +   +  +  EM+F  L K + ++ P+E+  
Sbjct  244  QAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEPVA  303

Query  296  LKELTFDVLTELTEKHFSGKTALYVELENENYHTGNFIGLTIHSDKGTYFFTKETAENSP  355
            +  ++++ +T+++   FS+   +Y E   +NYH   +IG++   +   Y  T  +   + 
Sbjct  304  V--ISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLATD  361

Query  356  AFKEWIESDASKVVYDAKKTMVAMHRLGYAVSGITFDIMLASYLLNPSDSIADFTSVAIR  415
            +FK+ ++   +   YD K++ V + +LG  + + ++D  LA+YLL+  +   +++++A  
Sbjct  362  SFKQVFQKPIA--TYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NELSTIA--  416

Query  416  HDYTEV--ETDEAVYGKGAKRSTPEERVVAPHLARKAVAIAVLEKRLLDDLEKNEQLALM  473
            + +T++  E D++VYGKGAKR+ P+  V+  HLARK   +     ++LD L  +EQL L 
Sbjct  417  RIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLY  476

Query  474  EDLELPLTFVLAQMEMQGVSVDTKRLEDMKVELAGRLKTLEESIHSLAGEEFNINSPKQL  533
            +++ELPL+ VLA+ME++G+ V+   L+DM  +    + +L + I  +AG+EFNINSPKQL
Sbjct  477  QNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQL  536

Query  534  GVILFEKLGLP--AVKKTKTGYSTAADVLESLSGKHAIIDEILLYRQLGKIQSTYIEGLL  591
            G ILFEK+ LP    KKTKTGYSTA DVLE L+   +I+  IL YRQ+ K+QSTY+ GL 
Sbjct  537  GSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQ  596

Query  592  KVTDKETHKVHTRFNQTLTQTGRLSSVDPNLQNIPIRLEEGRKIRQVFVPSQPGWKIFSA  651
                 +  K+HTR+ Q LTQTGRLSSVDPNLQNIPIRLE+GR IR+ F PS+ +  ++S+
Sbjct  597  DYILADG-KIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSS  655

Query  652  DYSQVELRVLAHISEDENLIYAFKHDYDIHTKTAMDVFHVEKE-EVDSLMRRQAKAVNFG  710
            DYSQ+ELRVLAHIS DE+LI AF+++ DIHT TAM VF ++K  +V +  RR+AKAVNFG
Sbjct  656  DYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFG  715

Query  711  IVYGISDYGLSQNLGITRKDAKDFIDRYFVSYPAVKEYMQDIVRFAKEKGYVETILHRRR  770
            IVYGISD+GLS+NLGITRK++K +ID YF  YP++K YM+++VR AK+KGYVET++ RRR
Sbjct  716  IVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRR  775

Query  771  YIPEIVSRNFNVRGFAERTAMNTPIQGSAADIIKKAMILMSDRlksekleaklllQVHDE  830
             +P+I SRNFNVR+FAERTA+N+PIQGSAADI+K AMI +   L++  + AK+LLQVHDE
Sbjct  776  ELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDE  835

Query  831  LIFEAPEAEIAKLEEIVPDVMENAVELSVPLKVDSAFGDTWYDAK  875
            +++E P+ E++ +  +V D ME AV+L+VPL VD + G++WY+AK
Sbjct  836  IVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

394) polA in NC_006582


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  672 bits (2540),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 430/886 (49%), Positives = 634/886 (72%), Gaps = 20/886 (2%)

Query  2    KKLVLIDGNSIAYRAFFAL----PLLNNEKGEYTNAVYGFTTMLLKVLEDEKPSHMLVAF  57
            +KL+LIDG+S+A+RAFFAL      ++N+ G  TNA+YGF  ML  ++   +P+H+LVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  58   DAGKSTFRHQTYAAYKGTRQKTPSELSGQIPMIHQVLDAFSIKRYEVDEYEADDIIGTAA  117
            DAGK+TFR + YA YK+ R KTP E+  Q++ I+++L A++I  YE+++YEADDIIGT  
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  118  TNAAKEG--FDVVVITGDKDLLQLVDDRVEVVLTKKGISEVDRYNREKVAERYGLEPKQI  175
              A +    FDV +++GDKDL+QL D+   V ++KKG++E + +    + E+ GL P+Q+
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  176  IDLKGLMGDSSDNIPGVPGVGEKTALKLLAEFRDVETVLDSIDAISGKKLKERLQENKDQ  235
            IDLK+LMGD SDNIPGV  +GEKT+LKLL EF  +E + + ID++   K+KE L +++DQ
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRDQ  244

Query  236  ALLSKKLATIALDVPLAETLDSFEYGGYEYKQVKEAFKELSFHSLLGRIDGNGDEESAPQ  295
            A+LSK LATI    P++  LD + Y G +   + + + E+ F  L   + +    + + +
Sbjct  245  AFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLAS----QMPQE  300

Query  296  QLTELDFDIVEEPLPEHFSSPSALVVEVLAENYHQAEIAGMAVANEKGCFYFPTEKAVKS  355
             ++ + ++ V +  ++ FS+   +  E L +NYH+  I G A ++    +       + +
Sbjct  301  PVAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLAT  360

Query  356  DAFR-AFARSQEKKKWLFDAKRAVVALAWHGVDLNGVDFDLQMASYLLDPSLSSHEISDI  414
            D+F+  F ++       +D KR+ V L+  G++L +  +D ++A+YLL +++  +E+S I
Sbjct  361  DSFKQVFQKPIAT----YDFKRSKVLLSHLGIELVAPSYDARLANYLL-STVEDNELSTI  415

Query  415  ATRKGTGGVAEDEAVYGKGAKRSLPEEAALAEHLCRKANAMFTLKSTledelaqneqlel  474
            A      ++ ED++VYGKGAKR++P+   L EHL RK + ++  KS + D L+ +EQL+L
Sbjct  416  ARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDL  475

Query  475  lkkleMPLSVVLGRMEKEGVRVDREQLEEMGKDLSDRLNTLEKAIHKEAGEPFNINSPKQ  534
             +++E+PL+ VL++ME EG++V+R  L++M+ +    +++L + I   AG+ FNINSPKQ
Sbjct  476  YQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQ  535

Query  535  LGVILFEKLGLP--PVKKTKTGYSTSADVLEKLAGTHPIIEHLLLYRQLGKLYSTYIEGL  592
            LG ILFEK+ LP    KKTKTGYST+ DVLE+LA   PI+  +L YRQ+ KL STY+ GL
Sbjct  536  LGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGL  595

Query  593  LKVIDSETGKVHTRFNQALTQTGRLSSTDPNLQNIPIRLEEGRKIRKAFVASKEGWKIVA  652
               I ++ GK+HTR+ Q LTQTGRLSS DPNLQNIPIRLE+GR IRKAF +S E+  +++
Sbjct  596  QDYILAD-GKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLS  654

Query  653  ADYSQIELRVLAHISGDERMKEAFLTGMDIHTKTAMDVFHV-KREEVTDLMRRSAKAVNF  711
            +DYSQIELRVLAHISGDE++  AF  G DIHT TAM VF + K  +VT   RR+AKAVNF
Sbjct  655  SDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNF  714

Query  712  GIVYGISDYGLSQSLGITRKEAKDFIDRYLASYPQVKAYMENVVKEAKEKGYVQTLLARR  771
            GIVYGISD+GLS++LGITRK++K +ID Y+  YP +KAYMENVV+EAK+KGYV+TL+ RR
Sbjct  715  GIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRR  774

Query  772  RYLPELKSRNFNQRSFAERTAMNTPIQGTAADIIKRAMVKMSEALEETGLKANMLLQVHD  831
            R LP+++SRNFN RSFAERTA+N+PIQG+AADI+K AM+++  AL+  G++A+MLLQVHD
Sbjct  775  RELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHD  834

Query  832  ELIFEVAPDDVEPLQELVTEVMEQALELDVPLQVDVSSGNSWFDAK  877
            E+++EV+ D++ +++ LV + ME A++L VPL VD S+G+SW++AK
Sbjct  835  EIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

395) polA in NC_006270


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  670 bits (2535),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 437/888 (50%), Positives = 639/888 (72%), Gaps = 17/888 (1%)

Query  1    MTERKKLVLVDGNSLAYRAFFAL----PLLSNEKGIHTNAVYGFTTILMKMLEEEKPTHM  56
            M +++KL+L+DG+S+A+RAFFAL      + N+ G+HTNA+YGF  +L  M+   +PTH+
Sbjct  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60

Query  57   LVAFDAGKTTFRHKTFKEYKGGRQKTPPELSEQLPFIRELLDAYRISRYELENYEADDII  116
            LVAFDAGKTTFR   + +YK+GR KTP E+ EQ+++IRE+L A  I+ YELE+YEADDII
Sbjct  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120

Query  117  GTLAKSAEKDG--FEVKIFSGDKDLTQLATEGTTVAITKKGITDVEYYTPEHVREKYGLT  174
            GTL K AE+    F+V I SGDKDL QL+ E T V I+KKG+++ E +TP  + EK GLT
Sbjct  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180

Query  175  PEQIIDMKGLMGDSSDNIPGVPGVGEKTAIKLLKQFHTVEELLSSIDEVSGkklkeklee  234
            P+Q+ID+K+LMGD SDNIPGV  +GEKT++KLL +F ++E +   ID     K+KE+L +
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  235  fkeQALMSKELATITTEAPLEVSLDSLGYEGFDREAVVKIFKDLGFHSLLerigeeagek  294
             ++QA++SK LATI T +P+ ++LD + Y+G D  ++ +++ +++F  L   ++ +  + 
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQE  300

Query  295  eeeqleeIDVMIKTDITDDLFASPASLVVEQLGDNYHEAPILGFSIVNEHGAFFIPEETA  354
                +   +V   T+++ DLF++   +  E L DNYH  +I+GF+  + +  +   + + 
Sbjct  301  PVAVISYQEV---TNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSL  357

Query  355  VQSDCFKEWAEDESKKKWVFDAKRAAVALRWRGIELKGAEFDVLLAAYIINPGHSYDDVA  414
            + +D FK+  +   K    +D KR+ V L   GIEL ++ +D  LA Y+++  +  ++++
Sbjct  358  LATDSFKQVFQ---KPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NELS  413

Query  415  SVAKEHQLHIVSADEAVYGKGAKQAVPDEKELADHLARKAKAISllreklldeleeneql  474
            ++A+      +  D++VYGKGAK+AVPD   L +HLARK K +   + ++LD L  +EQL
Sbjct  414  TIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQL  473

Query  475  elfealeMPLAHILGEMESIGVQVDVDRLKKMGEELSAKLAEYEKKIHESAGETFNINSP  534
            +L++ +E+PLA++L+ ME  G++V+   L+ M+E+    +    + I + AG+ FNINSP
Sbjct  474  DLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSP  533

Query  535  KQLGVILFDKLGLP--VVKKTKTGYSTSADVLEKLRDKHVIIEDILHYRQIGKLQSTYVE  592
            KQLG ILF+K+ LP  + KKTKTGYST+ DVLE+L     I+  IL+YRQI KLQSTYV 
Sbjct  534  KQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVI  593

Query  593  GLLKVIKKDSHKVHTRFNQALTQTGRLSSTDPNLQNIPIRLEEGRKIRQAFVPSQKGWLI  652
            GL   I  D+ K+HTR+ Q LTQTGRLSS DPNLQNIPIRLE+GR IR+AF PS+ + ++
Sbjct  594  GLQDYILADG-KIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVL  652

Query  653  FAADYSQIELRVLAHISKDKNLIEAFTNDMDVHTKTAMDVFHVS-EEEVTPAMRRQAKAV  711
            +++DYSQIELRVLAHIS D +LI AF ++ D+HT TAM VF +    +VT+  RR+AKAV
Sbjct  653  LSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAV  712

Query  712  NFGIVYGISDYGLSQNLGITRKEAAAFIERYFHSFQGVKEYMEETVQEAKQRGYVTTLLS  771
            NFGIVYGISD+GLS+NLGITRK++ ++I+ YF+ + G+K YME+ V+EAK++GYV TL+ 
Sbjct  713  NFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFK  772

Query  772  RRRYIPELTSRNFNLRSFAERTAMNTPIQGSAADIIKKAMIDMADKLKEKNLQAKLLLQV  831
            RRR +P++ SRNFN+RSFAERTA+N+PIQGSAADI+K AMI++   L+   ++AK+LLQV
Sbjct  773  RRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQV  832

Query  832  HDELIFEAPEDEIKVLEKLVPEVMEHALELDVPLKVDCASGPSWYDAK  879
            HDE+++E P+DE+  + KLV + ME A++L VPL VD ++G SWY+AK
Sbjct  833  HDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

396) polA in NC_006322


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  670 bits (2535),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 437/888 (50%), Positives = 639/888 (72%), Gaps = 17/888 (1%)

Query  1    MTERKKLVLVDGNSLAYRAFFAL----PLLSNEKGIHTNAVYGFTTILMKMLEEEKPTHM  56
            M +++KL+L+DG+S+A+RAFFAL      + N+ G+HTNA+YGF  +L  M+   +PTH+
Sbjct  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60

Query  57   LVAFDAGKTTFRHKTFKEYKGGRQKTPPELSEQLPFIRELLDAYRISRYELENYEADDII  116
            LVAFDAGKTTFR   + +YK+GR KTP E+ EQ+++IRE+L A  I+ YELE+YEADDII
Sbjct  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120

Query  117  GTLAKSAEKDG--FEVKIFSGDKDLTQLATEGTTVAITKKGITDVEYYTPEHVREKYGLT  174
            GTL K AE+    F+V I SGDKDL QL+ E T V I+KKG+++ E +TP  + EK GLT
Sbjct  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180

Query  175  PEQIIDMKGLMGDSSDNIPGVPGVGEKTAIKLLKQFHTVEELLSSIDEVSGkklkeklee  234
            P+Q+ID+K+LMGD SDNIPGV  +GEKT++KLL +F ++E +   ID     K+KE+L +
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  235  fkeQALMSKELATITTEAPLEVSLDSLGYEGFDREAVVKIFKDLGFHSLLerigeeagek  294
             ++QA++SK LATI T +P+ ++LD + Y+G D  ++ +++ +++F  L   ++ +  + 
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQE  300

Query  295  eeeqleeIDVMIKTDITDDLFASPASLVVEQLGDNYHEAPILGFSIVNEHGAFFIPEETA  354
                +   +V   T+++ DLF++   +  E L DNYH  +I+GF+  + +  +   + + 
Sbjct  301  PVAVISYQEV---TNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSL  357

Query  355  VQSDCFKEWAEDESKKKWVFDAKRAAVALRWRGIELKGAEFDVLLAAYIINPGHSYDDVA  414
            + +D FK+  +   K    +D KR+ V L   GIEL ++ +D  LA Y+++  +  ++++
Sbjct  358  LATDSFKQVFQ---KPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NELS  413

Query  415  SVAKEHQLHIVSADEAVYGKGAKQAVPDEKELADHLARKAKAISllreklldeleeneql  474
            ++A+      +  D++VYGKGAK+AVPD   L +HLARK K +   + ++LD L  +EQL
Sbjct  414  TIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQL  473

Query  475  elfealeMPLAHILGEMESIGVQVDVDRLKKMGEELSAKLAEYEKKIHESAGETFNINSP  534
            +L++ +E+PLA++L+ ME  G++V+   L+ M+E+    +    + I + AG+ FNINSP
Sbjct  474  DLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSP  533

Query  535  KQLGVILFDKLGLP--VVKKTKTGYSTSADVLEKLRDKHVIIEDILHYRQIGKLQSTYVE  592
            KQLG ILF+K+ LP  + KKTKTGYST+ DVLE+L     I+  IL+YRQI KLQSTYV 
Sbjct  534  KQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVI  593

Query  593  GLLKVIKKDSHKVHTRFNQALTQTGRLSSTDPNLQNIPIRLEEGRKIRQAFVPSQKGWLI  652
            GL   I  D+ K+HTR+ Q LTQTGRLSS DPNLQNIPIRLE+GR IR+AF PS+ + ++
Sbjct  594  GLQDYILADG-KIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVL  652

Query  653  FAADYSQIELRVLAHISKDKNLIEAFTNDMDVHTKTAMDVFHVS-EEEVTPAMRRQAKAV  711
            +++DYSQIELRVLAHIS D +LI AF ++ D+HT TAM VF +    +VT+  RR+AKAV
Sbjct  653  LSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAV  712

Query  712  NFGIVYGISDYGLSQNLGITRKEAAAFIERYFHSFQGVKEYMEETVQEAKQRGYVTTLLS  771
            NFGIVYGISD+GLS+NLGITRK++ ++I+ YF+ + G+K YME+ V+EAK++GYV TL+ 
Sbjct  713  NFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFK  772

Query  772  RRRYIPELTSRNFNLRSFAERTAMNTPIQGSAADIIKKAMIDMADKLKEKNLQAKLLLQV  831
            RRR +P++ SRNFN+RSFAERTA+N+PIQGSAADI+K AMI++   L+   ++AK+LLQV
Sbjct  773  RRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQV  832

Query  832  HDELIFEAPEDEIKVLEKLVPEVMEHALELDVPLKVDCASGPSWYDAK  879
            HDE+++E P+DE+  + KLV + ME A++L VPL VD ++G SWY+AK
Sbjct  833  HDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

397) polA in NC_012491


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  668 bits (2524),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 426/898 (48%), Positives = 633/898 (71%), Gaps = 39/898 (4%)

Query  2    SHFVLIDGNSVANRAFYAL----PLLSTSAGLHTNAVLGFTTMLLKVLEEMKPTHIMVAF  57
            + ++LIDG+SVA RAF+AL      +   +GLHTNA+ GF  ML  ++  ++PTH++VAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  58   DAGKVVFRHSEYAEYKGGRSKTPPELSEQFPLIRELLDAFSIKRFELEGYEADDIIGTLT  117
            DAGK  FR   YA+YK+GR+KTP E+ EQF+ IRE+L A++I  +ELE YEADDIIGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  118  KQAD--EQAWKTTVITGDKDMLQLVSEHVSVALTRKGVSEIEMYTPEEIHEKYGLKPLQI  175
            K A+  E +   T+++GDKD++QL  E+  V +++KGV+E+E +TP  + EK GL P Q+
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  176  IDLKGLMGDSSDNIPGVPGVGEKTALKLLHEYGSVEQVLENIDKVSGKKLQENLRENVDK  235
            IDLK+LMGD SDNIPGV  +GEKT+LKLLHE+GS+E + E+ID     K++ENL ++ D+
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRDQ  244

Query  236  ANMSKALATILREAPVELDVQETGFEGYDGLPVSEFFKKMEFKSLLSKIKVAQPEGGSGQ  295
            A +SK+LATI   +P+ +++++  ++G D  ++S+F+  M+F  L   +    P+   + 
Sbjct  245  AFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEPVA-  303

Query  296  ADAKPFSFEMISEENKAAYESKLTSPMALYIEMDGENYHHAPFLGIGLATEDTVMFVPWD  355
                 +S++ +++ +   +    ++   +Y+E   +NYH+ +++G++           W+
Sbjct  304  ----VISYQEVTNVSADLF----SAEDIFYFETLRDNYHREAIIGFA-----------WG  344

Query  356  VAKE---WKALCEWLADPAKEKW-----VFDGKRDTVGLAWHDFAIKGISFDVYLASYLL  407
             + +      L    +D+ K+        +D KR  V L+  ++ + + S+D  LA+YLL
Sbjct  345  HGEQIYASTDLSLLATDSFKQVFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLL  404

Query  408  NAAESNPTLDSIAAQYAQTRVLSDEEVYGKGAKRLVPEMDVLSEHVAHKAAAIWQSVPVL  467
            ++ E N  L +IA  +++  +  D+ VYGKGAKR VP+ DVL EH+A+K   + +S + +
Sbjct  405  STVEDN-ELSTIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQM  463

Query  468  REQLAENEMEKLLGELEAPLSMVLALMEKQGVKVNSERLVQMGEDLDKKLAGLTDQIYEL  527
             ++L+ +E   L  ++E PL+ VLA ME +G+KVN   L +M+E+    + +LT++IY++
Sbjct  464  LDKLTAHEQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDM  523

Query  528  AGGAFNINSPKQLGEILFDRLSLP--VLKKTKTGPSTSADVLEKLAPYHPIIDAILTFRQ  585
            AG  FNINSPKQLG ILF+++ LP  + KKTKTG ST+ DVLE+LAP  PI+  IL +RQ
Sbjct  524  AGQEFNINSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQ  583

Query  586  LGKLRSTYIEGLTKEIHTKTSKVHTLYNQATTATGRLSSTDPNLQNIPIRMEEGRKIREA  645
            + KL+STY+ GL   I +  +K+HT Y Q  T TGRLSS DPNLQNIPIR+E+GR IR A
Sbjct  584  ITKLQSTYVIGLQDYILAD-GKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKA  642

Query  646  FIPSEDGWYMLAADYSQIELRILAHISQDENLIDAFQKGMDIHTRTAMDVFGVS-EEEVT  704
            F PS+++  +L++DYSQIELR+LAHIS DE+LI AF+ G DIHT TAM VFG+    +VT
Sbjct  643  FTPSHEDAVLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVT  702

Query  705  SLMRRQAKAVNFGIVYGISDYGLSQNLNITRKEAGDFIERYFDVFSGVKRWMDEIVQQAK  764
            +  RR+AKAVNFGIVYGISD+GLS+NL ITRK++  +I+ YF+ ++G+K  M+++V++AK
Sbjct  703  ANDRRNAKAVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAK  762

Query  765  ADGHVTTLLNRRRYLPDIRSSNFNLRSFAERTAMNTPIQGTAADVIKLAMIRMQEALEEK  824
              G V TL++RRR LPDI S NFN+RSFAERTA+N+PIQG+AAD++K+AMI ++ AL+  
Sbjct  763  DKGYVETLFKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAG  822

Query  825  GLASRMLLQVHDELVFEVPDNELEVMRKLVPEVMESALSLDVPLKVDVSDGRTWYDAK  882
            G+ ++MLLQVHDE+V+EVP++EL  ++KLV + ME+A+ L VPL VD S G++WY+AK
Sbjct  823  GFRAKMLLQVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

398) HPL003_16285 in NC_016641


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  664 bits (2510),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 438/898 (49%), Positives = 630/898 (71%), Gaps = 37/898 (4%)

Query  2    DKLMLIDGNSIIYRAFFAM----PPLTNSSGQQTNAVYGFTTMLLRLLEEHKPTHILVAF  57
            +KL+LIDG+S+ +RAFFA+      + N SG +TNA+YGF  ML +++   +PTH+LVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  58   DAGKITFRHKGYEDYKGGREKTPPELSQQFPLLKELLTAFGIAQFELDGYEADDIIGTLS  117
            DAGK TFR   Y DYK+GR KTP E+ +QF+ ++E+LTA+GIA +EL+ YEADDIIGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  118  KTAD--EAGFNVLVVTGDKDMLQLASDNVTVGLTRKGVTEVETYGPEQIQERYGLKPLQI  175
            K A+  E  F+V +V+GDKD++QL+ +N  V +++KGV+E E + P  + E+ GL P Q+
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  176  IDLKGLMGDTSDNIPGIPGVGEKTALKLLHQYGSVEEVLAHTDELK-GKMKERVETHADD  234
            IDLK+LMGD SDNIPG+  +GEKT+LKLLH++GS+E +  H D +K +KMKE +  + D+
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRDQ  244

Query  235  ARMSKDLATIYRDVTLDKQLEDVVFDGLQAETGGPALAKLEFKSLLERLSFSGEVGSAGI  294
            A +SK LATI     +   L+D+V++G +  + +     ++F  L             G+
Sbjct  245  AFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQL-----------KKGL  293

Query  295  GVEEAAADVTVLDEQRISEL-VNVLDTVDLLHVETHGDNPHHAEIVGLVFGAAGRQFFMT  353
            + + +   V+V+  Q ++++  +++ + D++  ET  DN H+  I+G+  G + + +  T
Sbjct  294  ASQMPQEPVAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYAST  353

Query  354  -LAVLQTDAAKPVREWLADAGCKKRGHDLHRTDLALHWHGIEFAGAEFDVQLAGYLLDPT  412
             L++L TD+ K V +    +       D+ R+ + L   GIE+ ++ +D +LA YLL   
Sbjct  354  DLSLLATDSFKQVFQKPIAT------YDFKRSKVLLSHLGIELVAPSYDARLANYLLSTV  407

Query  413  DANQSLSGLAAKYGLSSIRPDDEVFGKGAKYKVPDVDVLSDHVARKAAVIEALVPVQQAE  472
            + N+ LS +A  +   S+  DD V+GKGAK  VPD DVL +H+ARK  V   L+  +   
Sbjct  408  EDNE-LSTIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKV---LLDSKSQM  463

Query  473  LEKTEMH---KLFHELEMPLSRILADMEKQGILVNVEELRALGKEFEAQIETLVREIYII  529
            L+K   H    L++++E+PL+ +LA ME +GI VN   L+ ++ +    IE+L +EIY +
Sbjct  464  LDKLTAHEQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDM  523

Query  530  AGVEFNLNSPKQLGEILFDKLGLP--VIKKTKTGYSTDAEVLEKLAPYHDIVQNILQYRT  587
            AG EFN+NSPKQLG ILF+K+ LP  + KKTKTGYST  +VLE+LAP   IV +IL+YR 
Sbjct  524  AGQEFNINSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQ  583

Query  588  IAKLQSTYVEGLLKEISDKTGKLHTYFRQTVAATGRLSSQFPNLQNIPIRLEEGRKIRKV  647
            I+KLQSTYV GL ++     GK+HT + Q ++ TGRLSS  PNLQNIPIRLE+GR IRK 
Sbjct  584  ITKLQSTYVIGL-QDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKA  642

Query  648  FVPSEPGWSILAADYSQIELRVLADISDDERLKEAFVHDMDIHTKTASDVFGI-PAEDVD  706
            F PS+ +  +L++DYSQIELRVLA+IS+DE+L  AF ++ DIHT TA  VFGI  A DV 
Sbjct  643  FTPSHEDAVLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVT  702

Query  707  SNMRRSAKAVNFGIVYGISDYGLSQNLNITRKEAARFIDQYFDVFQGVRRYMDDIVKDAK  766
            +N RR+AKAVNFGIVYGISD+GLS+NL ITRK++  +ID YF+ + G++ YM+++V++AK
Sbjct  703  ANDRRNAKAVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAK  762

Query  767  RDGYVKTLLERRRYLPEINASNFNLRSFAERTAMNTPIQGTAADIIKLAMVQMDAALRDR  826
              GYV TL+ RRR LP+IN+ NFN+RSFAERTA+N+PIQG+AADI+K+AM+++D AL+  
Sbjct  763  DKGYVETLFKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAG  822

Query  827  NLRSRMLLQVHDELVFEVPPEEMETMKELVPATMEAALKLAVPLKAEVSYGSNWYEAK  884
             +R++MLLQVHDE+V+EVP +E+ ++K LV  TMEAA+ LAVPL  + S G +WYEAK
Sbjct  823  GFRAKMLLQVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

399) GYMC10_4912 in NC_013406


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  657 bits (2482),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 425/897 (48%), Positives = 624/897 (70%), Gaps = 33/897 (3%)

Query  2    DKLILIDGNNIIYRAFFAM----PPLTNASGQQTNAVYGFTTMLLRLIEEHKPTHMMVAF  57
            +KL+LIDG+++ +RAFFA+      + N SG +TNA+YGF  ML +++   +PTH++VAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  58   DAGKETFRHADFQEYKGGRQKTPPELSGQFPLLKELLKGLGVSQFEIGGYEADDIIGTIT  117
            DAGK TFR   + +YK+GR KTP E+  QF+ ++E+L +LG++ +E+  YEADDIIGT+ 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  118  RQAD--EAGRKVMVVSGDKDMLQLASEHTTIAMVRKGVTEIEYYGPEQIKERYNLTPDQI  175
            + A+  E    V +VSGDKD++QL+ E+T + + +KGV+E+E + P  + E+  LTP+Q+
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  176  IDLKGLMGDASDNIPGVPGVGEKTALKLLHEFGSVEAVVSRTDELK-GKMKEKIEEHADS  234
            IDLK+LMGD SDNIPGV  +GEKT+LKLLHEFGS+E++  + D +K +KMKE++ ++ D 
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRDQ  244

Query  235  AILSKKLATIFREVPLEQSLDEMAFTGLNEETAGPALAKLEFKSLIERLNLSTSGAPGDA  294
            A+LSK LATI    P+  +LD++ + G +  + +     ++F  L   L    +  P   
Sbjct  245  AFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEP---  301

Query  295  AESKPEAKIDVTLVDATGIAEVADHL-AQVTVLHVETHGDNPHHADVIGLALATEERQYF  353
                      V+++    +++V+ +L +   ++  ET  DN H+  +IG+A +  E+ Y 
Sbjct  302  ----------VAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYA  351

Query  354  LP-FDVLKSEEAEPVRAWLADSEIPKRGYDLHRIDLALHWQGIAFAGAAFDVHLAAYLLD  412
               + +L ++    V       + P   YD+ R  + L   GI + ++++D +LA YLL 
Sbjct  352  STDLSLLATDSFKQV------FQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLS  405

Query  413  PTESNQTLSGLASKYGLAYLQADEDVFGKGAKYKVPDVEKLSEHMARKCLAVSELVPIQE  472
              E N+ LS +A  +    L+ D+ V+GKGAK  VPD + L EH+ARK   + +  +   
Sbjct  406  TVEDNE-LSTIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQML  464

Query  473  KELAANEMLPLFHDLEMPLSRILADMEKQGIAVNAEDLKELGREFEGQIAKLVQEIYEIA  532
              L+A+E L L++++E+PL+ +LA ME +GI VN   L++++ +    I  L QEIY++A
Sbjct  465  DKLTAHEQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMA  524

Query  533  GTEFNLNSPKQLGEILFVKLELP--VIKKTKTGYSTDAEVLEKLAPYHDIVRLILQYRTL  590
            G EFN+NSPKQLG ILF K++LP  + KKTKTGYST  +VLE+LAP   IV  IL+YR +
Sbjct  525  GQEFNINSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQI  584

Query  591  AKLQSTYVEGLLKEISSVTGKVHTYYRQTIAATGRLSSQYPNLQNIPIRLEEGRKLRKVF  650
            +KLQSTYV GL ++     GK+HT Y Q ++ TGRLSS  PNLQNIPIRLE+GR +RK F
Sbjct  585  TKLQSTYVIGL-QDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAF  643

Query  651  VPSEPGWSILAADYSQIELRVLAHISDDERLKEAFVHDMDIHTKTAMDVFGVGMD-EVDS  709
             PS+ +  +L++DYSQIELRVLAHIS+DE+L  AF ++ DIHT TAM VFG++   +V +
Sbjct  644  TPSHEDAVLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTA  703

Query  710  NMRRSAKAVNFGIVYGISDYGLSQNLNITRKEAAAFIDQYFEVFQGVRRYMDVIVKQAKQ  769
            N RR+AKAVNFGIVYGISD+GLS+NL ITRK++ ++ID YFE + G++ YM+ +V++AK+
Sbjct  704  NDRRNAKAVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKD  763

Query  770  DGYVKTLLERRRYLPEINASNFNLRSFAERTAMNTPIQGTAADIIKLAMVHMDKALHERQ  829
             GYV TL+ RRR LP+IN+ NFN+RSFAERTA+N+PIQG+AADI+K+AM+++DKAL+   
Sbjct  764  KGYVETLFKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGG  823

Query  830  LKSRMLLQVHDELVFEVPEDELEVMKELVPDVMSQALKLSVPLKSEVSYGENWYEAK  886
            ++++MLLQVHDE+V+EVP+DEL  +K LV D M  A+ L+VPL  + S G++WYEAK
Sbjct  824  FRAKMLLQVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

400) SAMSHR1132_15210 in NC_016941


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  655 bits (2477),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 416/890 (47%), Positives = 632/890 (72%), Gaps = 29/890 (3%)

Query  2    NKLVLIDGNSLSFRAFYAL----PLLSNKAGIHTNAVYGFAMLLEKILKEEKPDHFLVAF  57
            NKL+LIDG+S++FRAF+AL      + N +G+HTNA+YGF ++L+ ++K  +P H LVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  58   DAGKTTFRHEKYSEYKGGRQKTPPELSEQFPYIRQLLDAYHIKRYELDNYEADDIIGTLS  117
            DAGKTTFR E Y++YK+GR KTP E+ EQF+YIR++L A  I  YEL++YEADDIIGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  118  KEADKAG--FQTIIITGDRDLTQLATDNVTIYYTKKGVTDVDHYTPEFISEKYNGLTPSQ  175
            K A+++   F+  I++GD+DL QL+ +N  +  +KKGV++ +++TP ++ EK  GLTP+Q
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEK-MGLTPNQ  183

Query  176  IIDMKGLMGDSSDNIPGVAGVGEKTAIKLLNQFNTVEGVYEHLEEVSGkklkekleNSKE  235
            +ID+K+LMGD SDNIPGV+ +GEKT++KLL++F ++EG+YEH++     K+KE+L N ++
Sbjct  184  FIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRD  243

Query  236  DALMSKELATINVDSPIEVSLEDTLMTNQNDqqekielfkklefkqllGDLDQTVGKAES  295
            +A++SK LATIN  SPI ++L+D +    +              +   G L   + +   
Sbjct  244  QAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKG-LASQMPQEPV  302

Query  296  EEKTFDIETTFDKVDFDSLKEAAIHLELDGGNYLKDNILKFS------LFTGDKHVVINA  349
               +++  T      F +  E  + +E   +NY ++ I+ F+      ++++    ++ +
Sbjct  303  AVISYQEVTNVSADLFSA--EDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLAT  360

Query  350  EDIKKHKELVKWLENPNTKKVVYDAKKTYVASHRLNINIQNITFDIMLASYIIDPSRTIS  409
            + +K+       +++P +    YD K++ V   +L I++   ++D  LA+Y++      +
Sbjct  361  DSFKQV------FQKPIA---TYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-N  410

Query  410  DVQSVVSLYGQSFVKDDVSIYGKGKKFKVPEDNVLNPYVASITDAIYFSKPNMDKQLEEY  469
            ++ ++  ++ +  + +D ++YGKG K  VP+ +VL   +A     +  SK++M  +L   
Sbjct  411  ELSTIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAH  470

Query  470  NQVELLADLELPLAQILSKMEETGIYTDINDLKEMEIEIQQKLDVLIKNIHEAAGEAFNI  529
            +Q++L  ++ELPLA++L+KME  GI  +   L++M  + +  ++ L ++I + AG+ FNI
Sbjct  471  EQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNI  530

Query  530  NSPKQLGVVLFETLKLP--VIKKTKTGYSTAVDVLEQLQGEHPIIEYILEYRQLSKLQST  587
            NSPKQLG +LFE ++LP  + KKTKTGYSTAVDVLE+L    PI+  IL+YRQ++KLQST
Sbjct  531  NSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQST  590

Query  588  YVEGLQKVVSDDQRIHTRFNQTLAQTGRLSSVDPNLQNIPVRLEEGRKIRKAFKPTSKDS  647
            YV GLQ  +  D +IHTR+ Q L+QTGRLSSVDPNLQNIP+RLE+GR IRKAF P+  D+
Sbjct  591  YVIGLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDA  650

Query  648  VILSADYSQIELRVLAHITQDESMKEAFINGDDIHTATAMKVFGVE-ADQVDSLMRRQAK  706
            V+LS+DYSQIELRVLAHI+ DE +  AF +G DIHT+TAM+VFG++ A +V +  RR+AK
Sbjct  651  VLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAK  710

Query  707  AVNFGIVYGISDYGLSQSLGITRKKAKAFIDDYLASFPGVKQYMSDIVKDAKALGYVETL  766
            AVNFGIVYGISD+GLS++LGITRK++K++ID Y+  +PG+K YM ++V++AK  GYVETL
Sbjct  711  AVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETL  770

Query  767  LHRRRYIPDITSRNFNLRGFAERTAMNTPIQGSAADIIKLAMVKFAEKMKDTTYQAKLLL  826
            + RRR +PDI SRNFN+R+FAERTA+N+PIQGSAADI+K+AM+++   ++   ++AK+LL
Sbjct  771  FKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLL  830

Query  827  QVHDELIfevpksevesfsefveDIMENALQLDVPLKVDSSYGATWYDAK  876
            QVHDE+++EVP+ E+ ++  +V D ME A++L VPL VD S G +WY+AK
Sbjct  831  QVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

401) polA in NC_017542


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  653 bits (2470),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 428/900 (48%), Positives = 628/900 (70%), Gaps = 41/900 (4%)

Query  2    DKLMLIDGNSIIYRAFFAM----PPLTNSSGQQTNAVYGFTTMLLRLLEEHKPTHILVAF  57
            +KL+LIDG+S+ +RAFFA+      + N SG +TNA+YGF  ML +++   +PTH+LVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  58   DAGKITFRHKGYEDYKGGREKTPPELSQQFPLLKELLTAFGIAQFELDGYEADDIIGTLS  117
            DAGK TFR   Y DYK+GR KTP E+ +QF+ ++E+LTA+GIA +EL+ YEADDIIGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  118  RTAD--EAGFNVLVVTGDKDMLQLASDHVTVGLTRKGVTEVETYGPEQIQERYGLKPLQI  175
            + A+  E  F+V +V+GDKD++QL+ ++  V +++KGV+E E + P  + E+ GL P Q+
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  176  IDLKGLMGDTSDNIPGIPGVGEKTALKLLHQYGSVEEVLAHTDELK-GKMKERVETHADD  234
            IDLK+LMGD SDNIPG+  +GEKT+LKLLH++GS+E +  H D +K +KMKE +  + D+
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRDQ  244

Query  235  ARMSKELATIYRDVTLDKQLEDVVFSGLQAETAGPALAKLEFKSLLERlslsgevgsagv  294
            A +SK LATI     +   L+D+V++G +  + +     ++F  L             G+
Sbjct  245  AFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQL-----------KKGL  293

Query  295  gveeaaaDVTVLNEERISEL-VEVLNNINVLHVETHGDNPHHAEIVGLIFA-ATGRQFFM  352
            + + +   V+V++ + ++++  ++++  +++  ET  DN H+  I+G  FA + G Q++ 
Sbjct  294  ASQMPQEPVAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIG--FAWGHGEQIYA  351

Query  353  T--LNVLQSDAATPIREWLADPERKKRGHDLHRTDLALHWHGIEFAGAEFDVQLAGYLLD  410
            +  L++L +D+   +       ++     D+ R+ + L   GIE+ ++ +D +LA YLL 
Sbjct  352  STDLSLLATDSFKQV------FQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLS  405

Query  411  PTDANQTLSGLAAKYGLSSIRPDDEVFGKGAKYKVPEMDVLSDHVARKAAVIEALVPVQQ  470
              + N+ LS +A  +   S+  DD V+GKGAK  VP+ DVL +H+ARK  V   L+  + 
Sbjct  406  TVEDNE-LSTIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKV---LLDSKS  461

Query  471  AELEKTEMH---KLFHELEMPLSRILADMEKQGILVNVEELRALGKEFEAQIATLVGEIY  527
              L+K   H    L++++E+PL+ +LA ME +GI VN   L+ ++ +    I +L  EIY
Sbjct  462  QMLDKLTAHEQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIY  521

Query  528  SIAGVEFNLNSPKQLGEILFDKLGLP--VIKKTKTGYSTDAEVLEKLAPYHDIVQNILQY  585
             +AG EFN+NSPKQLG ILF+K+ LP  + KKTKTGYST  +VLE+LAP   IV +IL+Y
Sbjct  522  DMAGQEFNINSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDY  581

Query  586  RTIAKLQSTYVEGLLKEISEKTGKVHTYFRQTVAATGRLSSQFPNLQNIPIRLEEGRKIR  645
            R I+KLQSTYV GL ++     GK+HT + Q ++ TGRLSS  PNLQNIPIRLE+GR IR
Sbjct  582  RQITKLQSTYVIGL-QDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIR  640

Query  646  KVFVPSEPGWSILAADYSQIELRVLADISDDERLKEAFVHDMDIHTKTASDVFGV-PAEA  704
            K F PS+ +  +L++DYSQIELRVLA+IS+DE+L  AF ++ DIHT TA  VFG+  A  
Sbjct  641  KAFTPSHEDAVLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAAD  700

Query  705  VDSDMRRSAKAVNFGIVYGISDYGLSQNLNITRKEAARFIDQYFDVFQGVRRYMDDIVKD  764
            V ++ RR+AKAVNFGIVYGISD+GLS+NL ITRK++  +ID YF+ + G++ YM+++V++
Sbjct  701  VTANDRRNAKAVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVRE  760

Query  765  AKRDGYVKTLLERRRYLPEINASNFNQRSFAERTAMNTPIQGTAADIIKLAMVQMDAALR  824
            AK  GYV TL+ RRR LP+IN+ NFN RSFAERTA+N+PIQG+AADI+K+AM+++D AL+
Sbjct  761  AKDKGYVETLFKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQ  820

Query  825  ERNLRSRMLLQVHDELVFEVPPEEMETMKELVPATMEAALKLAVPLKAEVSYGSNWYEAK  884
               +R++MLLQVHDE+V+EVP +E+ ++K LV  TMEAA+ LAVPL  + S G +WYEAK
Sbjct  821  AGGFRAKMLLQVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

402) PPSC2_c1766 in NC_014622


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  653 bits (2470),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 428/900 (48%), Positives = 628/900 (70%), Gaps = 41/900 (4%)

Query  2    DKLMLIDGNSIIYRAFFAM----PPLTNSSGQQTNAVYGFTTMLLRLLEEHKPTHILVAF  57
            +KL+LIDG+S+ +RAFFA+      + N SG +TNA+YGF  ML +++   +PTH+LVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  58   DAGKITFRHKGYEDYKGGREKTPPELSQQFPLLKELLTAFGIAQFELDGYEADDIIGTLS  117
            DAGK TFR   Y DYK+GR KTP E+ +QF+ ++E+LTA+GIA +EL+ YEADDIIGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  118  RTAD--EAGFNVLVVTGDKDMLQLASDHVTVGLTRKGVTEVETYGPEQIQERYGLKPLQI  175
            + A+  E  F+V +V+GDKD++QL+ ++  V +++KGV+E E + P  + E+ GL P Q+
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  176  IDLKGLMGDTSDNIPGIPGVGEKTALKLLHQYGSVEEVLAHTDELK-GKMKERVETHADD  234
            IDLK+LMGD SDNIPG+  +GEKT+LKLLH++GS+E +  H D +K +KMKE +  + D+
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRDQ  244

Query  235  ARMSKELATIYRDVTLDKQLEDVVFSGLQAETAGPALAKLEFKSLLERlslsgevgsagv  294
            A +SK LATI     +   L+D+V++G +  + +     ++F  L             G+
Sbjct  245  AFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQL-----------KKGL  293

Query  295  gveeaaaDVTVLNEERISEL-VEVLNNINVLHVETHGDNPHHAEIVGLIFA-ATGRQFFM  352
            + + +   V+V++ + ++++  ++++  +++  ET  DN H+  I+G  FA + G Q++ 
Sbjct  294  ASQMPQEPVAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIG--FAWGHGEQIYA  351

Query  353  T--LNVLQSDAATPIREWLADPERKKRGHDLHRTDLALHWHGIEFAGAEFDVQLAGYLLD  410
            +  L++L +D+   +       ++     D+ R+ + L   GIE+ ++ +D +LA YLL 
Sbjct  352  STDLSLLATDSFKQV------FQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLS  405

Query  411  PTDANQTLSGLAAKYGLSSIRPDDEVFGKGAKYKVPEMDVLSDHVARKAAVIEALVPVQQ  470
              + N+ LS +A  +   S+  DD V+GKGAK  VP+ DVL +H+ARK  V   L+  + 
Sbjct  406  TVEDNE-LSTIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKV---LLDSKS  461

Query  471  AELEKTEMH---KLFHELEMPLSRILADMEKQGILVNVEELRALGKEFEAQIATLVGEIY  527
              L+K   H    L++++E+PL+ +LA ME +GI VN   L+ ++ +    I +L  EIY
Sbjct  462  QMLDKLTAHEQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIY  521

Query  528  SIAGVEFNLNSPKQLGEILFDKLGLP--VIKKTKTGYSTDAEVLEKLAPYHDIVQNILQY  585
             +AG EFN+NSPKQLG ILF+K+ LP  + KKTKTGYST  +VLE+LAP   IV +IL+Y
Sbjct  522  DMAGQEFNINSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDY  581

Query  586  RTIAKLQSTYVEGLLKEISEKTGKVHTYFRQTVAATGRLSSQFPNLQNIPIRLEEGRKIR  645
            R I+KLQSTYV GL ++     GK+HT + Q ++ TGRLSS  PNLQNIPIRLE+GR IR
Sbjct  582  RQITKLQSTYVIGL-QDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIR  640

Query  646  KVFVPSEPGWSILAADYSQIELRVLADISDDERLKEAFVHDMDIHTKTASDVFGV-PAEA  704
            K F PS+ +  +L++DYSQIELRVLA+IS+DE+L  AF ++ DIHT TA  VFG+  A  
Sbjct  641  KAFTPSHEDAVLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAAD  700

Query  705  VDSDMRRSAKAVNFGIVYGISDYGLSQNLNITRKEAARFIDQYFDVFQGVRRYMDDIVKD  764
            V ++ RR+AKAVNFGIVYGISD+GLS+NL ITRK++  +ID YF+ + G++ YM+++V++
Sbjct  701  VTANDRRNAKAVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVRE  760

Query  765  AKRDGYVKTLLERRRYLPEINASNFNQRSFAERTAMNTPIQGTAADIIKLAMVQMDAALR  824
            AK  GYV TL+ RRR LP+IN+ NFN RSFAERTA+N+PIQG+AADI+K+AM+++D AL+
Sbjct  761  AKDKGYVETLFKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQ  820

Query  825  ERNLRSRMLLQVHDELVFEVPPEEMETMKELVPATMEAALKLAVPLKAEVSYGSNWYEAK  884
               +R++MLLQVHDE+V+EVP +E+ ++K LV  TMEAA+ LAVPL  + S G +WYEAK
Sbjct  821  AGGFRAKMLLQVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

403) PPE_01596 in NC_014483


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  645 bits (2436),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 430/899 (48%), Positives = 624/899 (70%), Gaps = 39/899 (4%)

Query  2    DKLMLIDGNSIIYRAFFAM----PPLTNSSGQQTNAVYGFTTMLLRLLEEHKPTHILVAF  57
            +KL+LIDG+S+ +RAFFA+      + N SG +TNA+YGF  ML +++   +PTH+LVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  58   DAGKITFRHKGYEDYKGGREKTPPELSQQFPLLKELLTAFGIAQFELDGYEADDIIGTLS  117
            DAGK TFR   Y DYK+GR KTP E+ +QF+ ++E+LTA+GIA +EL+ YEADDIIGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  118  KTAD--EAGFNVLIVTGDKDMLQLASDHVTVGLTRKGVTEVETYGPEQIQERYGLKPLQI  175
            K A+  E  F+V IV+GDKD++QL+ ++  V +++KGV+E E + P  + E+ GL P Q+
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  176  IDLKGLMGDTSDNIPGIPGVGEKTALKLLHQYGSVEEVLAHTNELK-GKMKERVETHADD  234
            IDLK+LMGD SDNIPG+  +GEKT+LKLLH++GS+E +  H + +K +KMKE +  + D+
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRDQ  244

Query  235  ARMSKDLATIYRDVTLDKQLDDVAFGGLQAETAGPALAKLEFKSLLERLSFSGEVGSTGv  294
            A +SK LATI     +   LDD+ + G +  + +     ++F  L  + ++++++    V
Sbjct  245  AFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQL--KKGLASQMPQEPV  302

Query  295  dveeaaadvtvldeQRISelvevldrvdvlhveTHGDNPHHADIVGLIFA-ATGQQFFMT  353
             V            +  +   +++   D++  ET  DN H+  I+G  FA + G+Q++ +
Sbjct  303  AVISYQ--------EVTNVSADLFSAEDIFYFETLRDNYHREAIIG--FAWGHGEQIYAS  352

Query  354  --LDVLQSDAATPIRAWLADPERKKRGHDLHRTDLALHWHGIEFAGAEFDVQLAGYLLDP  411
              L +L +D+   +       ++     D+ R+ + L   GIE+ ++ +D +LA YLL  
Sbjct  353  TDLSLLATDSFKQV------FQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLST  406

Query  412  TDANQTLSGLAAKYGLSSIRPDEEVFGKGAKYKVPDVDVLSDHVARKAAVIEALVPVQQA  471
             + N+ LS +A  +   S+  D+ V+GKGAK  VPD DVL +H+ARK  V   L+  +  
Sbjct  407  VEDNE-LSTIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKV---LLDSKSQ  462

Query  472  ELEKTEMH---KLFHELEMPLSRILADMEKQGVLVNVEELRALGKEFEAQIATLVSEIYS  528
             L+K   H    L++++E+PL+ +LA ME +G+ VN   L+ ++ +    I +L  EIY 
Sbjct  463  MLDKLTAHEQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYD  522

Query  529  IAGVEFNLNSPKQLGEILFDKLGLP--VIKKTKTGYSTDAEVLEKLAPYHDIVQNILQYR  586
            +AG EFN+NSPKQLG ILF+K+ LP  + KKTKTGYST  +VLE+LAP   IV +IL+YR
Sbjct  523  MAGQEFNINSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYR  582

Query  587  TIAKLQSTYVEGLLKEISGKTGKVHTYFRQTVAATGRLSSQFPNLQNIPIRLEEGRKIRK  646
             I+KLQSTYV GL ++     GK+HT + Q ++ TGRLSS  PNLQNIPIRLE+GR IRK
Sbjct  583  QITKLQSTYVIGL-QDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRK  641

Query  647  VFVPSEPGWSILAADYSQIELRVLADISDDERLKEAFVHDMDIHTKTASDVFGVA-AEDV  705
             F PS+ +  +L++DYSQIELRVLA+IS+DE+L  AF ++ DIHT TA  VFG+  A DV
Sbjct  642  AFTPSHEDAVLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADV  701

Query  706  DSNMRRSAKAVNFGIVYGISDYGLSQNLNITRKEAARFIDQYFDVFQGVRRYMDDIVKDA  765
             +N RR+AKAVNFGIVYGISD+GLS+NL ITRK++  +ID YF+ + G++ YM+++V++A
Sbjct  702  TANDRRNAKAVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREA  761

Query  766  KRDGYVKTLLERRRYLPEINASNFNLRSFAERTAMNTPIQGTAADIIKLAMVQMDKVLRE  825
            K  GYV TL+ RRR LP+IN+ NFN+RSFAERTA+N+PIQG+AADI+K+AM+++DK L+ 
Sbjct  762  KDKGYVETLFKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQA  821

Query  826  RNLRSRMLLQVHDELVFEVPPEEMETMKELVPATMEAALELAVPLKAEVSYGSNWYEAK  884
              +R++MLLQVHDE+V+EVP +E+ ++K LV  TMEAA++LAVPL  + S G +WYEAK
Sbjct  822  GGFRAKMLLQVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

404) Exig_2202 in NC_010556


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  643 bits (2429),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 427/888 (49%), Positives = 633/888 (72%), Gaps = 38/888 (4%)

Query  4    NKLLLIDGNSLTYRAFFAL----PPMTDAQGRNTNAAYGFTMMLLKLLEEEQPTHMLVAF  59
            NKLLLIDG+S+++RAFFAL        +  G +TNA YGF +ML  ++   +PTH+LVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  60   DASSETFRHDVYQEYKGSREKTPSELREQFPIVRDICEALGIQMMELHRYEADDLIGTLA  119
            DA+  TFR ++Y +YK++R KTP E+REQF+ +R++  ALGI   EL++YEADD+IGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  120  QTMPADR------IRIVTGDKDLLQLVTSQVEVLITKRGITDVLCMTEELFAETY----G  169
            +   A+R      + IV+GDKDL+QL   +  V I+K+G+++      E F+ +Y     
Sbjct  125  KM--AERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEF-----EEFTPAYLMEKM  177

Query  170  GLKPIQMIDLKGLMGDKSDNIPGVPGIGEKTAIKLISAYGSVEGLYEHVEDLK-GKQKEK  228
            GL P Q IDLK+LMGDKSDNIPGV  IGEKT++KL+  +GS+EG+YEH++++K +K KE+
Sbjct  178  GLTPNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKEN  237

Query  229  VVANEELARLSKELATIKldvpldvtlddlQISDVDTQVPYSLFQSLGFKSLTNRFAPVV  288
            ++ + + A LSK LATI+   P+ + LDD+  ++ D      +++ ++F  L + +A+ +
Sbjct  238  LINDRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQM  297

Query  289  EEADKEQLNVQAITSLPEDV--TDAVLVVEQLREDYMEEDIIGFGIATPDQIYVASA-EL  345
             +     ++ Q +T+++ D+  ++ ++  E LR++Y  E IIGF+ +  +QIY ++   L
Sbjct  298  PQEPVAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSL  357

Query  346  VDDPAFRDWIESDHQKICLDAKQAAFALRKHGLKLTA--FDDlllagyllnlsggTTLAS  403
            +   +F++ ++        D K++   L   G+ L A  +D  L    L  + +   L++
Sbjct  358  LATDSFKQVFQK--PIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NELST  414

Query  404  IAGHYMLMA-PNEEAVLGKGAKRLAPADDVLHPYLAEKARMIELLFPKVK--EELKANQQ  460
            IA  +  ++  ++++V GKGAKR  P  DVL   LA K ++  LL +K +  + L A++Q
Sbjct  415  IARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKV--LLDSKSQMLDKLTAHEQ  472

Query  461  FELYETLERPLSGVLAEMEWTGIRVDVGTLQEMQHDLAGRLHDLEQLIYGEVGEEFNINS  520
            ++LY+ +E PL+ VLA ME  GI+V+ +TLQ+M ++    ++ L Q IY+  G+EFNINS
Sbjct  473  LDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINS  532

Query  521  PKQLGVILFEKMELP--AFKKTKTGYSTAADVLEKLRPLHPVIDHIMLYRELQKLQSTYV  578
            PKQLG ILFEKM+LP    KKTKTGYSTA DVLE+L P+ P++  I+ YR++ KLQSTYV
Sbjct  533  PKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYV  592

Query  579  EGLQKVIKEDGKIHTRFAQTIAQTGRLSSVNPNLQNIPVRIEEGRKIRKAFVPSEPGWSL  638
             GLQ  I  DGKIHTR+ Q ++QTGRLSSV+PNLQNIP+R+E+GR IRKAF PS+ +  L
Sbjct  593  IGLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVL  652

Query  639  YAADYSQIELRVMAHMSEDKTLVQAFLDDADIHTQTASSVFGVA-PNDVTGNMRRQAKAV  697
             ++DYSQIELRV+AH+S D  L+ AF ++ADIHT TA  VFG+  + DVT+N RR+AKAV
Sbjct  653  LSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAV  712

Query  698  NFGIIYGISDYGLSQNLNISRKEAQDFIDRYFELFPQIKLFMDAAIEKARMNGFVETLMN  757
            NFGI+YGISD+GLS+NL I+RK+++ +ID YFE +P IK +M+  +  A+ +G+VETL +
Sbjct  713  NFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFK  772

Query  758  RRRNIPDINSKNFNLRGFAERTAINTPIQGSAADIIKKAMLDVHAALEQSPLRARLLLQV  817
            RRR++PDINS+NFN+R+FAERTAIN+PIQGSAADI+K AM++++ AL+ + +RA++LLQV
Sbjct  773  RRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQV  832

Query  818  HDELIFEAPDEELDALKTLVKQAMEQTVQLSVPLRVDGDAGHSWYETK  865
            HDE+++E P++EL A+K LVK++ME +V+L+VPL VD  +G+SWYE+K
Sbjct  833  HDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

405) polA in NC_017668


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  642 bits (2428),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 417/888 (47%), Positives = 641/888 (73%), Gaps = 21/888 (2%)

Query  3    EKVVLIDGNSIAYRAFFAL----PLLNNDKGVYTNAVYGFTTMLLKILEEDQPDHLLVAF  58
            +K++LIDG+S+A+RAFFAL      ++N+ G+ TNA+YGF  ML  ++   +P H+LVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  59   DAGKTTFRHETYSEYKGGRQKTPPELSEQFPVLKELLDAFGAKYYQLNQYEADDIIGTIA  118
            DAGKTTFR E Y++YK+GR KTP E+ EQF+ ++E+L A+G  YY+L++YEADDIIGT+ 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  119  DQAGQDG--YEVKVISGDKDLLQLVTDRVSVSLTKKGITNVDTYDPSFMEEKMGVRPDQI  176
              A +    ++V ++SGDKDL+QL  +   V ++KKG+++ + + P+++ EKMG+ P+Q+
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  177  IDLKALMGDSSDNIPGVPGVGEKTAVKLLKQFDTIDRLYDNLDQVSGkklkekleNHKED  236
            IDLKALMGD SDNIPGV  +GEKT++KLL +F++++ +Y+++D     K+KE+L N++++
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRDQ  244

Query  237  AYMSRKLVTIERHAPIEIELKDLGYQGYQSTQVSHLFKDLGFQSLLSRVQEGGIEDESEA  296
            A++S+ L TI+  +PI I L D+ Y+G + + +S+++ +++F  L  +   + + +E+ A
Sbjct  245  AFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQL-KKGLASQMPQEPVA  303

Query  297  AEPFPDIKVEVVEDFEDDMFTGKEALVVEMLYDNYHQAAVEGIAIINESNKYVISMNNAK  356
              ++ +     V +   D+F++ + +  E L DNYH+ A+ G+A  +  + Y  +  +  
Sbjct  304  VISYQE-----VTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLL  358

Query  357  NSKGFkkwaeddkkekwVFDAKRTVVALMRHDVNIKGIQFDLLLASYLINPAENHHDIPA  416
             + +FK+  +        +D KR+ V L + ++++ +  +D  LA+YL++  E++ ++++
Sbjct  359  ATDSFKQVFQKPIA---TYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDN-ELST  414

Query  417  ISHRMGESKVKYDEEVYGKGAKMKRPENDNDFHEHISRKADMVYKLKDTVENELKNKEQY  476
            I++   +  +  D+ VYGKGAK   P++D  + EH++RK  ++   K  + + L   EQ 
Sbjct  415  IARIFTDISLEEDDTVYGKGAKRAVPDKDV-LLEHLARKVKVLLDSKSQMLDKLTAHEQL  473

Query  477  NLYMDLEMPLALILGRMEHRGVLVDQKRLEEMGAELESRLTAIEKDIFELAGESFNLNSP  536
            +LY ++E+PLA +L++ME  G+ V++  L++M+ +    + A+ ++I+++AG+ FN+NSP
Sbjct  474  DLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSP  533

Query  537  KQLGPILFEKLNLP--VIKKTKTGYSTSADVLEQLEDQHEIISSILMYRQLGKLKSTYIE  594
            KQLG+ILFEK++LP  + KKTKTGYST+ DVLE+L     I++ IL YRQ+ KL+STY+ 
Sbjct  534  KQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVI  593

Query  595  GLLKVINEDTHKIHTRFNQALTQTGRLSSTEPNLQNIPIRLEEGRKIRQAFIPSKENWVI  654
            GL   I  D  KIHTR+ Q LTQTGRLSS +PNLQNIPIRLE+GR IR+AF PS E+ V+
Sbjct  594  GLQDYILADG-KIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVL  652

Query  655  FASDYSQIELRVLAHIAQDEKLIEAFREGQDIHTQTASEVFGVAKE-DVTSEMRRQAKAV  713
            ++SDYSQIELRVLAHI+ DE LI AF EG DIHT TA  VFG+ K  DVT++ RR+AKAV
Sbjct  653  LSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAV  712

Query  714  NFGIVYGISDYGLSQSLDIPRKEAQAFIDKYLESYPGVKTYMEETVQEAKQVGYVTTFMN  773
            NFGIVYGISD+GLS++L+I RK+++++ID Y+E YPG+K+YME+ V+EAK+ GYV T+ +
Sbjct  713  NFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFK  772

Query  774  RRRYLPELTSRNFNRRNAAERTAMNTPIQGSAADVIKKAMIDlenrlaeenleaKMLLQV  833
            RRR LP++ SRNFN R+ AERTA+N+PIQGSAAD++K AMI+L++ L    + AKMLLQV
Sbjct  773  RRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQV  832

Query  834  HDelileapeeeveqlkevvASVMEQTVKLDVPLKVDYSYGSTWYDAK  881
            HDE++LE P++E+  +K +V   ME +V L VPL VD S G +WY+AK
Sbjct  833  HDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

406) polA in NC_018665


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  640 bits (2419),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 420/894 (47%), Positives = 636/894 (72%), Gaps = 50/894 (5%)

Query  4    NKLLLIDGNSLTYRAFFAL----PPMTDAQGRNTNAAYGFTMMLLKLLEEEQPTHMLVAF  59
            NKLLLIDG+S+++RAFFAL        +  G +TNA YGF +ML  ++   +PTH+LVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  60   DASSETFRHDVYQEYKGSREKTPSELREQFPIVRDICEALGIQMMELHRYEADDLIGTLA  119
            DA+  TFR ++Y +YK++R KTP E+REQF+ +R++  ALGI   EL++YEADD+IGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  120  QTMPADR------IRIVTGDKDLLQLVTDQVEVLITKRGITDVLCMTEELFAETY----G  169
            +   A+R      + IV+GDKDL+QL  ++  V I+K+G+++      E F+ +Y     
Sbjct  125  KM--AERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEF-----EEFTPAYLMEKM  177

Query  170  GLKPMQMIDLKGLMGDKSDNIPGVPGIGEKTAIKLISAYGSVEGLYEHVEDLK-GKQKEK  228
            GL P Q IDLK+LMGDKSDNIPGV  IGEKT++KL+  +GS+EG+YEH++++K +K KE+
Sbjct  178  GLTPNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKEN  237

Query  229  VIANEELARLSKELATIKldvpldvtlddlQISDVDTQIPYSLFQSLGFKSLTNRFAPVV  288
            +I + + A LSK LATI+   P+ + LDD+  ++ D      +++ ++F  L + +A+ +
Sbjct  238  LINDRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQM  297

Query  289  EEADKEQLNVKTISSLPLDV--TDAVLVVEQLREDYMEEDIIGFGIATPDQIYVASQ-EL  345
             +     ++ + +++++ D+  ++ ++  E LR++Y  E IIGF+ +  +QIY +++  L
Sbjct  298  PQEPVAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSL  357

Query  346  LLDPAFRAWIES-------DHQKICLDAKQVAFALRKHDLKLTAFDDlllagyllnlsgg  398
            L   +F+  ++         + K+ L    + +     D +L+ +        LL+   +
Sbjct  358  LATDSFKQVFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANY--------LLSTVED  409

Query  399  TTLASIAGHYMLMA-PNEEVVLGKGAKRLTPTDDLLHPYLAEKARMIELLF---PKVVEE  454
              L++IA  +  ++  +++ V GKGAKR  P  D+L   L + AR + +L+   +++++ 
Sbjct  410  NELSTIARIFTDISLEEDDTVYGKGAKRAVPDKDVL---LEHLARKVKVLLDSKSQMLDK  466

Query  455  LKANQQFELYETLERPLSGVLAEMEWTGIRVDVATLQEMQQDLGGRLNDLEQLIYGEVGE  514
            L A++Q++LY+ +E PL+ VLA ME  GI+V+ ATLQ+M ++    ++ L Q IY+  G+
Sbjct  467  LTAHEQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQ  526

Query  515  EFNINSPKQLGVILFEKLELP--AFKKTKTGYSTAADVLEKLRPLHPVIDHIMLYRELQK  572
            EFNINSPKQLG ILFEK++LP    KKTKTGYSTA DVLE+L P+ P++  I+ YR++ K
Sbjct  527  EFNINSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITK  586

Query  573  LQSTYVEGLQKVIKEDGKIHTRFAQTIAQTGRLSSVNPNLQNIPVRIEEGRKIRKAFVPS  632
            LQSTYV GLQ  I  DGKIHTR+ Q ++QTGRLSSV+PNLQNIP+R+E+GR IRKAF PS
Sbjct  587  LQSTYVIGLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPS  646

Query  633  EPGWSLYAADYSQIELRVMAHMSEDETLVQAFLDDADIHTQTASSVFGVE-PNDVTGNMR  691
            + +  L ++DYSQIELRV+AH+S DE L+ AF ++ADIHT TA  VFG++ + DVT+N R
Sbjct  647  HEDAVLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDR  706

Query  692  RQAKAVNFGIIYGISDYGLSQNLNISRKEAQEFIDRYFELFPQIKLFMDAAIEKARMNGF  751
            R+AKAVNFGI+YGISD+GLS+NL I+RK+++ +ID YFE +P IK +M+  +  A+ +G+
Sbjct  707  RNAKAVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGY  766

Query  752  VETLMNRRRNIPDINSKNFNLRGFAERTAINTPIQGSAADIIKKAMLDVHAALEQSPLQA  811
            VETL +RRR++PDINS+NFN+R+FAERTAIN+PIQGSAADI+K AM++++ AL+ + ++A
Sbjct  767  VETLFKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRA  826

Query  812  RLLLQVHDELIFEAPDEELDELKSLVKQAMEQTVHLSVPLRVDGDAGHSWYETK  865
            ++LLQVHDE+++E P++EL  +K LVK++ME +V+L+VPL VD  +G+SWYE+K
Sbjct  827  KMLLQVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

407) BATR1942_12330 in NC_014639


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  637 bits (2406),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 440/890 (50%), Positives = 644/890 (73%), Gaps = 20/890 (2%)

Query  1    MTERKKLVLVDGNSLAYRAFFAL----PLLSNDKGIHTNAVYGFTMILMKMLEDEKPTHM  56
            M +++KL+L+DG+S+A+RAFFAL      + N+ G+HTNA+YGF ++L  M+   +PTH+
Sbjct  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60

Query  57   LVAFDAGKTTFRHSTFKEYKGGRQKTPPELSEQMPFIRELLDAYQISRYELEQYEADDII  116
            LVAFDAGKTTFR   + +YK+GR KTP E+ EQ ++IRE+L A  I+ YELE+YEADDII
Sbjct  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120

Query  117  GTLAKSAEKDG--FEVKIFSGDKDLTQLATEHTTVAITRKGITDVEFYTPQHVEEKYGLT  174
            GTL K AE+    F+V I SGDKDL QL+ E+T V I++KG+++ E +TP  + EK GLT
Sbjct  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180

Query  175  PEQIIDMKGLMGDSSDNIPGVPGVGEKTAIKLLKQFHSVEKLLESIGEVSGkklkeklee  234
            P+Q+ID+K+LMGD SDNIPGV  +GEKT++KLL +F S+E + E I+     K+KE+L +
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  235  fkDQAVMSKELATIMTDAPIDISLAELDYDGFNREQVISIFKDLGFNTLLERLGeengea  294
             +DQA +SK LATI T +PI I+L ++ Y+G +   +  ++ +++F  L   L+ +  + 
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQE  300

Query  295  eqqqefeDVDIHKVEEVTSGMLVSPSAFVVEQIGDNYHEAPILGFSLVNETGHYYIPKEI  354
                    +  + V +V+++++ +   F  E + DNYH  +I+GF+   +  + Y + ++
Sbjct  301  PVAV----ISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAW-GHGEQIYASTDL  355

Query  355  AV-QSEIFKKWAEDESQKKWVFDSKRSVVALRWQGIELKGAEFDALLAAYIINPANTYDD  413
            ++  ++ FK+  +        +D KRS V L   GIEL ++ +DA LA Y+++  +  ++
Sbjct  356  SLLATDSFKQVFQKPIA---TYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NE  411

Query  414  VASVAKDYGLHIVSSDEAVYGKGAKRAVPGENELAMHLVRKAAAVDSLRekllqelennd  473
            ++++A+ +    +  D++VYGKGAKRAVP+ + L  HL RK   +   + ++L+ L  ++
Sbjct  412  LSTIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHE  471

Query  474  qlelyeelelplalilgeMESIGVKVDVGRLERMGEELGARLKEYEEKIHEIAGEPFNIN  533
            QL+LY+++ELPLA +L+ ME  G+KV+ + L+ M+E+    +    + I ++AG+ FNIN
Sbjct  472  QLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNIN  531

Query  534  SPKQLGVILFEKLGLP--VVKKTKTGYSTSADVLEKLADQHDIVSYILQYRQIGKLQSTY  591
            SPKQLG ILFEK+ LP  + KKTKTGYST+ DVLE+LA    IV+ IL+YRQI KLQSTY
Sbjct  532  SPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTY  591

Query  592  IEGLLKVIRKDSHKVHTRFNQALTQTGRLSSTDPNLQNIPIRLEEGRKIRQAFVPSEKDW  651
            + GL   I  D+ K+HTR+ Q LTQTGRLSS DPNLQNIPIRLE+GR IR+AF PS+ D 
Sbjct  592  VIGLQDYILADG-KIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDA  650

Query  652  LIFAADYSQIELRVLAHISKDENLIEAFTNDMDVHTKTAMDVFHVAQD-EVTPAMRRQAK  710
            +++++DYSQIELRVLAHIS DE+LI AF ++ D+HT TAM VF + +  +VT+  RR+AK
Sbjct  651  VLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAK  710

Query  711  AVNFGIVYGISDYGLSQNLGITRKEAAAFIERYLESFKGVKVYMEESVQEAKQKGYVTTL  770
            AVNFGIVYGISD+GLS+NLGITRK++ ++I+ Y+E + G+K YME+ V+EAK+KGYV TL
Sbjct  711  AVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETL  770

Query  771  MQRRRYIPELTSRNFNLRSFAERTAMNTPIQGSAADIIKKAMIDMaaklkekqlkaklll  830
             +RRR +P++ SRNFN+RSFAERTA+N+PIQGSAADI+K AMI++   L+   ++AK+LL
Sbjct  771  FKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLL  830

Query  831  qVHDELIFEAPKEEIKLLEKLVPEVMEHALNLDVPLKVDFASGPSWYDAK  880
            QVHDE+++E P++E+  + KLV + ME A++L VPL VD ++G SWY+AK
Sbjct  831  QVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

408) polA in NC_013791


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  635 bits (2398),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 428/884 (49%), Positives = 629/884 (72%), Gaps = 18/884 (2%)

Query  2    KKLILIDGNSIAYRAFFAL----PLLNNDKGVYTNAVYGFTTMLLKIIQEEKPTHMLVAF  57
            +KL+LIDG+S+A+RAFFAL      ++N+ G+ TNA+YGF  ML  +++  +PTH+LVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  58   DAGKTTFRHKTYEEYKGGRQKTPPELSEQFPLIRELLDAFNIKRFELDNYEADDIIGTLS  117
            DAGKTTFR   Y +YK+GR KTP E+ EQF+ IRE+L A+ I  +EL++YEADDIIGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  118  keaekekwe--vkvvSGDKDLLQLVSDYVTVVLTKKGITNVESYDEALIDEKYGIKPHQI  175
            K AE+      V +VSGDKDL+QL  +   V ++KKG+++ E +  A + EK G+ P+Q+
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  176  IDMKGLMGDSSDNIPGVPGVGEKTALKLLKQFGTIENVLDSVDDVSGkklkeklsenkeQ  235
            ID+K+LMGD SDNIPGV  +GEKT+LKLL +FG++E + + +D+    K+KE+L ++++Q
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRDQ  244

Query  236  ALMSKELATIFTEVPYNLTLDELKFGEYDEEKVVSLFKELEFKSLVDQFDTGVSAAEKEL  295
            A++SK LATI T  P  + LD++ +   D   +  ++ E++F  L   + + +  ++  +
Sbjct  245  AFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQM--PQEPV  302

Query  296  EELSFDVVEEVKEEHLATPAAMVVEVLDENYHQADIAGFALVHEKGRYFIPTETALRSDL  355
              +S++ V +V  + +++      E L +NYH+  I GFA  H    Y     + L +D 
Sbjct  303  AVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLATDS  362

Query  356  FVE-WAKDETKKKWLLDAKRGVVVLGWKdvlldgvdfdllMAsylldpshsshdlsdIAT  414
            F +   K  +      D KR+ V+L+  ++ L +  +D  +A+YLL   + ++  + IA 
Sbjct  363  FKQVFQKPIAT----YDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELST-IAR  417

Query  415  RKGAKSIQADEAVYGKGAKRKVPETDVLAEHLVRKANVIYelkermeeelkkneQFELFK  474
                 S++ D++VYGKGAKR VP+ DVL EHL RK +V+ + K +M + L  +EQ++L++
Sbjct  418  IFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQ  477

Query  475  DLEMPLSVVLGRMETEGVKVDIDQLKAMGEDLASRLAELEKHIHEHAGVSFNINSPKQLG  534
            ++E+PL+ VL++ME EG+KV+   L+ M+E+    +  L ++I + AG  FNINSPKQLG
Sbjct  478  NIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLG  537

Query  535  EVLFEKLGLP--VIKKTKTGYSTSADVLEKLAEDHEIIRHILHYRQLGKLNSTYIEGLVK  592
             +LFEK+ LP  + KKTKTGYST+ DVLE+LA    I+  IL+YRQ+ KL+STY+ GL  
Sbjct  538  SILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQD  597

Query  593  VTHKGTSKIHTRFNQALTQTGRLSSTDPNLQNIPIRLEEGRKIRKAFIPSEEGWKILAAD  652
                + +KIHTR+ Q LTQTGRLSS DPNLQNIPIRLE+GR IRKAF PS+E+  +L++D
Sbjct  598  YIL-ADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSD  656

Query  653  YSQIELRVLAHIAQDEKLITAFKEDMDVHTKTAMDVFHVS-EEDVTSMMRRSAKAVNFGI  711
            YSQIELRVLAHI+ DE LI+AF+E+ D+HT TAM VF +    DVT+  RR+AKAVNFGI
Sbjct  657  YSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGI  716

Query  712  VYGISDYGLSQSLGITRKEAAKFIERYLASYPNVAEYMERIIEEARENGYVSTLLNRRRY  771
            VYGISD+GLS++LGITRK++  +I+ Y+  YP +  YME ++ EA+++GYV TL++RRR 
Sbjct  717  VYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRE  776

Query  772  LPELTSRNFNQRSFAERTAMNTPIQGTAADIIKKAMVEMALRLEEANLKSRLLLQVHDEL  831
            LP++ SRNFN RSFAERTA+N+PIQG+AADI+K AM+++   L+ + +++++LLQVHDE+
Sbjct  777  LPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEI  836

Query  832  IFEVPPEEVDEMMKIVPEVMENAVELAVPLKVDISAGDTWYDAK  875
            ++EVP +E+  + K+V + ME AV+LAVPL VD S+G++WY+AK
Sbjct  837  VLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

409) Aaci_2345 in NC_013205


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  629 bits (2378),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 419/908 (47%), Positives = 609/908 (68%), Gaps = 59/908 (6%)

Query  15   SKLVLIDGNSILYRAFFAL----PPLTARDGTPTNAVYGFTTMILRLMSDEKPTHLAVAF  70
            +KL+LIDG+S+ +RAFFAL      +  + G  TNA+YGF  M+ ++M   +PTH+ VAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  71   DKSKTTFRHADFAAYKGTRQETPDELVQQFPLARRTLEALSIPMVEIDQYEADDVIGTLA  130
            D +KTTFR   +A YK+ R  TPDE+ +QF+  R  L AL+I+  E+++YEADD+IGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  131  KRA--AEAGFDVRVVSGDKDLLQLVDDRIHVLLTRKGITEMEHFDEQAVARRYPGLKPAQ  188
            K A  +E  FDV +VSGDKDL+QL D+   V +++KG++E E+F    +  +  GL P Q
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEK-MGLTPNQ  183

Query  189  VIDLKGLMGDPSDNIPGVPGVGEKTALKLLASFGTVEGVYDHLDEVQGQKLRERLEQHRE  248
             IDLK+LMGD SDNIPGV  +GEKT+LKLL  FG++EG+Y+H+D  +  K++E L ++R+
Sbjct  184  FIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRD  243

Query  249  DAFLSKRLATIACDAPIEVDLETLRYEGPDPARAIAWFRELDFRSLVDKISEEMshdstp  308
            +AFLSK LATI   +PI ++L+ + Y+GPD A     + E+DF  L   ++ +M++++ +
Sbjct  244  QAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEPVA  303

Query  309  tpspaaasgassewssfaYGLIEDAGAWQEAISSFSEPVGVMMDLADPDYHRAEIRGMAV  368
              S               Y  + + +A       FS       +    +YHR  I G A 
Sbjct  304  VIS---------------YQEVTNVSA-----DLFSAEDIFYFETLRDNYHREAIIGFAW  343

Query  369  ATPKRAYYVRFGERLELSDVRPW-LVSDRPKVAFDLKSMAFALDAHGIGLTSECGWQDVK  427
            +   + Y    +  L L    +   V ++P  ++D+K     L   GI L +     D +
Sbjct  344  GHGEQIY---ASTDLSLLATDSFKQVFQKPIATYDFKRSKVLLSHLGIELVAPS--YDAR  398

Query  428  LAAYLLNPQDG-----------EVELSD---VFARERGQELPAWEEGEREKWLAYTASQL  473
            LA YLL+  ++           ++ L +   V+++   + +P     +++  L   A ++
Sbjct  399  LANYLLSTVEDNELSTIARIFTDISLEEDDTVYGKGAKRAVP-----DKDVLLEHLARKV  453

Query  474  PPLFES---LAYTIRMQEMERLYQEVELPLAFVLAKMEITGFYVNREKLVAFGQELTERI  530
              L++S   +   +  +E   LYQ++ELPLA VLAKMEI G+ VNR  L   +++    I
Sbjct  454  KVLLDSKSQMLDKLTAHEQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVII  513

Query  531  KRITQEIYDLAGTSFNLNSPKQLGEILFDKLGLP--ALKKTKTGYSTSADVLEKLAPMHE  588
              +TQEIYD+AG  FN+NSPKQLG ILF+K+ LP    KKTKTGYST+ DVLE+LAP+  
Sbjct  514  EALTQEIYDMAGQEFNINSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAP  573

Query  589  IVQKILDYRLLAKLQSTYVEGLLKVIRKETGRVHTRFHQTLTATGRLSSSEPNLQNIPIR  648
            IV KILDYR ++KLQSTYV GL   I  + G++HTR+ Q LT TGRLSS +PNLQNIPIR
Sbjct  574  IVAKILDYRQITKLQSTYVIGLQDYILAD-GKIHTRYVQDLTQTGRLSSVDPNLQNIPIR  632

Query  649  LEEGRRLRQVFEPTYKDWVIFAADYSQIELRILAHLSGDEALIDAFRRDMDIHTRTAADV  708
            LE+GR +R+ F P+  D V++++DYSQIELR+LAH+SGDE LI AF  + DIHT TA  V
Sbjct  633  LEQGRLIRKAFTPSHEDAVLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRV  692

Query  709  FEVP-PEQVTSLMRRQAKAVNFGIVYGISDFGLAQNLNIPQKEAKRFIESYFEKFPGVKR  767
            F +  + +VT+  RR+AKAVNFGIVYGISDFGL++NL I +K++K +I++YFE++PG+K 
Sbjct  693  FGIDKAADVTANDRRNAKAVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKA  752

Query  768  YMDEIVKQARERGYVTTLMNRRRYLPDIHSRNYQLRSFAERTAMNTPIQGSAADLIKLAM  827
            YM+++V++A+++GYV TL +RRR LPDI+SRN+++RSFAERTA+N+PIQGSAAD++K+AM
Sbjct  753  YMENVVREAKDKGYVETLFKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAM  812

Query  828  VRIDRAMRDAQMDARMLLQVHDELIFECPKDELAALEVLVRDNMENAMTLSVPLKVDTAY  887
            + +D+A++ +   A+MLLQVHDE+++E P+DEL+A+  LV+D ME A+ L+VPL VD + 
Sbjct  813  INLDKALQAGGFRAKMLLQVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDEST  872

Query  888  GPTWYDAK  895
            G +WY+AK
Sbjct  873  GQSWYEAK  880

410) polA in NC_017167


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  629 bits (2377),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 422/919 (46%), Positives = 610/919 (67%), Gaps = 81/919 (8%)

Query  4    SKLVLIDGNSILYRAFFAL----PPLTARDGTPTNAVYGFTTMILRLMSDEKPTHLAVAF  59
            +KL+LIDG+S+ +RAFFAL      +  + G  TNA+YGF  M+ ++M   +PTH+ VAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  60   DKSKTTFRHADFAAYKGTRQETPDELVQQFPLARRTLEALSIPMIEIDQYEADDVIGTLA  119
            D +KTTFR   +A YK+ R  TPDE+ +QF+  R  L AL+I+  E+++YEADD+IGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  120  KRA--AEAGFDVRVVSGDKDLLQLVDSSIHVLLTRKGITEMEHFDEQAVARRYPGLKPAQ  177
            K A  +E  FDV +VSGDKDL+QL D +  V +++KG++E E+F    +  +  GL P Q
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEK-MGLTPNQ  183

Query  178  VIDLKGLMGDPSDNIPGVPGVGEKTALKLLASFGTVEGVYEHLDEVQGQKLRERLEQHRE  237
             IDLK+LMGD SDNIPGV  +GEKT+LKLL  FG++EG+YEH+D  +  K++E L ++R+
Sbjct  184  FIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRD  243

Query  238  DAFLSKRLATIACDAPIEVDLEALRYEGPDPARAIAWFRELDFRSLVDKISEEMSHdsta  297
            +AFLSK LATI   +PI ++L+ + Y+GPD A     + E+DF  L   ++ +M++++ A
Sbjct  244  QAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEPVA  303

Query  298  apspadarsassewssfaysLIEDAGSWKEIVSSFSEPVGVMMDLADPD-----------  346
                                           V S+ E   V  DL  ++           
Sbjct  304  -------------------------------VISYQEVTNVSADLFSAEDIFYFETLRDN  332

Query  347  YHRAEIRGMAVATPKRAYYVRFGERLELSDVRPW-LVSDRPKVAFDLKSMAFALDAHGIG  405
            YHR  I G A +   + Y    +  L L    +   V ++P  ++D+K     L   GI 
Sbjct  333  YHREAIIGFAWGHGEQIY---ASTDLSLLATDSFKQVFQKPIATYDFKRSKVLLSHLGIE  389

Query  406  LTSASGWQDVKLAAYLLNPQDG-----------EVELSD---VFARERGQELPALEEGER  451
            L ++S   D +LA YLL+  ++           ++ L +   V+++   + +P     ++
Sbjct  390  LVAPS--YDARLANYLLSTVEDNELSTIARIFTDISLEEDDTVYGKGAKRAVP-----DK  442

Query  452  EKWLAYTASQLPPLFES---LAYTIRMQEMERLYQEVELPLAFVLAKMEITGFYVNREKL  508
            +  L   A ++  L++S   +   +  +E   LYQ++ELPLA VLAKMEI G+ VNR  L
Sbjct  443  DVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNIELPLANVLAKMEIEGIKVNRATL  502

Query  509  VAFGQELTERIKRITEEIYDLAGTSFNLNSPKQLGEILFDKLGLP--ALKKTKTGYSTSA  566
               +++    I  +T+EIYD+AG  FN+NSPKQLG ILF+K+ LP    KKTKTGYST+ 
Sbjct  503  QDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSILFEKMQLPLEMTKKTKTGYSTAV  562

Query  567  DVLEKLAPMHEIVQKILDYRLLAKLQSTYVEGLLKVIRKETGRVHTRFHQTLTATGRLSS  626
            DVLE+LAP+  IV KILDYR ++KLQSTYV GL   I  + G++HTR+ Q LT TGRLSS
Sbjct  563  DVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYILAD-GKIHTRYVQDLTQTGRLSS  621

Query  627  SEPNLQNIPIRLEEGRRLRQVFEPTYKDWVIFAADYSQIELRILAHLSGDEALIDAFRRD  686
             +PNLQNIPIRLE+GR +R+ F P+  D V++++DYSQIELR+LAH+SGDE LI AF  +
Sbjct  622  VDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQIELRVLAHISGDEHLIAAFNEG  681

Query  687  MDIHTRTAADVFEVP-PEQVTSLMRRQAKAVNFGIVYGISDFGLAQNLNIPQKEAKRFIE  745
             DIHT TA  VF +  + +VT+  RR+AKAVNFGIVYGISDFGL++NL I +K++K +I+
Sbjct  682  ADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGISDFGLSNNLGITRKQSKSYID  741

Query  746  SYFEKFPGVKRYMDEIVKQARERGYVTTLMNRRRYLPDIHSRNYQLRSFAERTAMNTPIQ  805
            +YFE++PG+K YM+++V++A+++GYV TL +RRR LPDI+SRN+++RSFAERTA+N+PIQ
Sbjct  742  TYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDINSRNFNVRSFAERTAINSPIQ  801

Query  806  GSAADLIKLAMVRIDRAMRDAQMDARMLLQVHDELIFECPKDELAALEVLVRDNMENAMT  865
            GSAAD++K+AM+ +D+A++ +   A+MLLQVHDE+++E P+DEL+A+  LV+D ME A+ 
Sbjct  802  GSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEVPNDELTAIKKLVKDTMEAAVD  861

Query  866  LSVPLKVDTAYGPTWYDAK  884
            L+VPL VD + G +WY+AK
Sbjct  862  LAVPLCVDESTGQSWYEAK  880

411) Pjdr2_1523 in NC_012914


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  619 bits (2339),  Expect = 3e-178, Method: Compositional matrix adjust.
 Identities = 422/901 (47%), Positives = 626/901 (70%), Gaps = 37/901 (4%)

Query  2    DKWILIDGNSIANRAFYAM----PPLTNSAGLHTNAVFGFTTMLLKLLEDEKPTHVLVAF  57
            +K +LIDG+S+A RAF+A+      + N +GLHTNA++GF  ML  ++   +PTHVLVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  58   DAGKVVFRHEGYTEYKGGRAKTPSELSEQFPVMKDLLKAFGISQFELSGYEADDIIGTLT  117
            DAGK  FR E Y++YK+GRAKTP E+ EQF+ ++++L A+GI+ +EL  YEADDIIGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  118  RLADEQKV--ETLVVTGDKDMLQLASDNVTIAITRKGISEVEHFSPAAIDEKYGLKPMQI  175
            ++A+   V  +  +V+GDKD++QL+ +N  + I++KG++E E+F+PA + EK GL P Q+
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  176  IDLKGLMGDASDNIPGIPGVGEKTALKMLHEFGTVEEVLANTESLK-GKMKEKVETHKDD  234
            IDLK+LMGD SDNIPG+  +GEKT+LK+LHEFG++E +  + +++K +KMKE++  ++D+
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRDQ  244

Query  235  AIMSKKLATIFREVPLEHSAEDIRYEGYQPATLADAFRKLEFKSLIERLDLngagagsne  294
            A++SK LATI    P+  + +DI Y+G + A+L++ +  ++F  L   L           
Sbjct  245  AFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLA----------  294

Query  295  saapaVELNIVVIESDNDGEALKDMLSALQGTEHGLYVEAIGENPHQAEVLGLAAAVGDT  354
              +   +  + VI  ++  +   D++SA    E+ +Y E++ +N H+  ++G+A + G+ 
Sbjct  295  --SQMPQEPVAVISYQEVTNVSADLFSA----EDIFYFETLRDNYHREAIIGFAWGHGEQ  348

Query  355  AYVVPVAAL--QQPFTAELRKWLEDADKPKNGFDTHKIELALGWRGIEWHGAAFDVQLAA  412
             Y     +L   ++F   +       +KP   +D  +  + L+  GIE  ++++D +LA 
Sbjct  349  IYASTDLSLLATDSFKQVF-------QKPIATYDFKRSKVLLSHLGIELVAPSYDARLAN  401

Query  413  YlldptdtnltlnalCDRYGQSSVPHDEAVYGKGAKFKVPDNETLHRHLSAKADAVRKLT  472
            YLL   + N         + + S+ +D++VYGKGAK  VPD++ L  HL+ K   +    
Sbjct  402  YLLSTVEDNELSTI-ARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSK  460

Query  473  SLMRADLEKRGMNELYFELEQPLSVILAGMERQGIKVEKAELERLGSELETKLSAAVSEI  532
            S M   L  +   +LY ++E PL+ +LA ME +GIKV++A L+ ++ +    + A   EI
Sbjct  461  SQMLDKLTAHEQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEI  520

Query  533  YRLAEMEFNIGSPKQLGEVLFEKLGLPVQ--KKTKTGYSTDAEVLEKLAPYHEIVPLILH  590
            Y +A  EFNI SPKQLG +LFEK+ LP++  KKTKTGYST  +VLE+LAP   IV+ IL+
Sbjct  521  YDMAGQEFNINSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILD  580

Query  591  YRTLSKLQSTYIEGLLKEVRPETGKIHTYYRQTIAATGRLSSQFPNLQNIPIRLEEGRQI  650
            YR ++KLQSTY+ GL   + ++ GKIHT Y Q ++ TGRLSS  PNLQNIPIRLE+GR I
Sbjct  581  YRQITKLQSTYVIGLQDYILAD-GKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLI  639

Query  651  RKAFVPSEPGWYILAADYSQIELRVLAHISGDERLKEAFIHDMDIHTKTAMDVFGVS-AD  709
            RKAF PS+ +  +L++DYSQIELRVLAHISGDE+L  AF ++ DIHT TAM VFG+  A 
Sbjct  640  RKAFTPSHEDAVLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAA  699

Query  710  QVDSNMRRSAKAVNFGIVYGISDFGLSQNLNITRKEAAKFIEQYFEVFQGVRKYMDDIVM  769
            +V +N RR+AKAVNFGIVYGISDFGLS+NL ITRK++  +I+ YFE + G++ YM+++V 
Sbjct  700  DVTANDRRNAKAVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVR  759

Query  770  QARRDGFVTTLLERRRYLPDIKASNFNLRSFAERTAMNTPIQGTAADIIKLAMVRMNETL  829
            +A+  G+V TL+ RRR LPDI++ NFN+RSFAERTA+N+PIQG+AADI+K+AM+ ++ +L
Sbjct  760  EAKDKGYVETLFKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKAL  819

Query  830  RERGLKSRMLLQVHDelvfevpeeelelmkelvPSTMAGALTLDVPLKADVNYGVNWYEA  889
            +  G++++MLLQVHDE+V+EVP++EL  +K LV  TM +A+ L VPL  D + G +WYEA
Sbjct  820  QAGGFRAKMLLQVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEA  879

Query  890  K  890
            K
Sbjct  880  K  880

412) polA in NC_018664


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  596 bits (2251),  Expect = 2e-171, Method: Compositional matrix adjust.
 Identities = 387/904 (43%), Positives = 616/904 (69%), Gaps = 42/904 (4%)

Query  2    SSKKLMIIDGNSLLHRAFYAL----PPLSTAEGIYTNGVYGFLTMFYKVIDEYKPDYISV  57
            + +KL++IDG+S+  RAF+AL      +    G+ TN++YGF  M+  ++   +P  + V
Sbjct  3    NKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLV  62

Query  58   VFDKKGPTFRHKEFADYKAGRAKTPDELLTQFPILKEVLDKLNISRLELDGFEADDLAGT  117
             FD    TFR   +ADYKAGRAKTPDE+  QF+ ++E+L  L I+  EL+ +EADD+ GT
Sbjct  63   AFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGT  122

Query  118  LVKMGE--EQGLNVIAVSGDKDYLQLASEKTSILLTRKGITELEIYDYDEVVKRYEMTPK  175
            L KM+E  E  ++V  VSGDKD +QL+ E+T + +++KG++E+E +    ++ +  +TP+
Sbjct  123  LDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPN  182

Query  176  QFIDLKGLMGDKSDNIPGVPGIGEKTGVKLLKEFKTIEGIYENIDSLR-GKMKENLVEYR  234
            QFIDLK+LMGDKSDNIPGV  IGEKTG+KLL EF ++EGIYE+ID+++ +KMKENL++ R
Sbjct  183  QFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDR  242

Query  235  NQAFMSRRLSEIITTIPLNIDIEDMKIKEPNYEEISELYQKLEFKSLLEKIGGNYTDNKS  294
            +QAF+S+ L+ I T+ P+ I+++D+  + P+   +S++Y+ ++F  L   ++++  +   
Sbjct  243  DQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQ---  299

Query  295  EEIVELEYKIIDKIEDVEKVYSEIKKSGEL----TFKTSFENNPLTGEVLGLAIK-YDPK  349
            E +  + Y      ++V +V +++  + ++    T++ +++ +++ G   G + + Y + 
Sbjct  300  EPVAVISY------QEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYAST  353

Query  350  DNYYINLEEIDKEVFFDISKEILEDRDIKKISHNIKEDIIILLRYGIDLQGIDFDSMIAQ  409
            D     L  +  + F    K++++       + ++K   ++L + GI+L +  +D+ +A+
Sbjct  354  D-----LSLLATDSF----KQVFQKP---IATYDFKRSKVLLSHLGIELVAPSYDARLAN  401

Query  410  YLINPSQSNYDINLLTKEYLKRDIHSEEDILGKGKSKNFKDLDIEETSKFFVNIVDSIFN  469
            YL++  + N +++ +++ +    ++ ++ + GKG  +   D D+      +   V  +++
Sbjct  402  YLLSTVEDN-ELSTIARIFTDISLEEDDTVYGKGAKRAVPDKDV--LLEHLARKVKVLLD  458

Query  470  IRPTIEIILKEQEMEELFYDVEIPLATVLADMEYRGFTVDLESLKELGNEFDKKIEILTA  529
             ++ +   L  +E  +L+ ++E+PLA VLA ME  G+ V+  +L++++++    IE LT 
Sbjct  459  SKSQMLDKLTAHEQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQ  518

Query  530  EIYKYSETEFNINSPKQLGEILFNKLELP--VIKKTKTGYSTNAEVLEKLIDSHPIVEKI  587
            EIY  +  EFNINSPKQLG ILF+K++LP  + KKTKTGYST  +VLE+L    PIV KI
Sbjct  519  EIYDMAGQEFNINSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKI  578

Query  588  LEYRQIVKLKSTYVDGLIN-VMDKNTNKVHSSFNQTITTTGRISSTEPNLQNIPIRTEEG  646
            L+YRQI KL+STYV GL + ++     K+H+ + Q +T TGR+SS +PNLQNIPIR E+G
Sbjct  579  LDYRQITKLQSTYVIGLQDYIL--ADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQG  636

Query  647  RKIRKVFIPKSEDYTLADADYSQIELRVLAHLSNDPKLIEAFFTGEDIHRRTASEVFDVP  706
            R IRK F P  ED  L  +DYSQIELRVLAH+S D  LI AF  G DIH  TA  VF++ 
Sbjct  637  RLIRKAFTPSHEDAVLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGID  696

Query  707  -LDEVTSTMRSNAKAVNFGIIYGISDFGLSRDLNISRKQSKEYIDNYFERYTNVKGFMDS  765
               +VT+  R NAKAVNFGI+YGISDFGLS +L I+RKQSK YID YFERY  +K++M++
Sbjct  697  KAADVTANDRRNAKAVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMEN  756

Query  766  IIKDGKKKGYVETILKRRRYLPELSSRNFNIRSFGERMAMNTPIQGSAADIIKVAMVGVY  825
            +++++K KGYVET++KRRR LP+++SRNFN+RSF+ER A+N+PIQGSAADI+K+AM+ + 
Sbjct  757  VVREAKDKGYVETLFKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLD  816

Query  826  YELKQRKLKSRLILQVHDELIVEAYKDEIEEVKELLRNIMEKSIKLNVPLKVDMKTGDSW  885
              L+   ++++++LQVHDE+++E  +DE+  +K L+++ ME ++ L VPL VD  TG+SW
Sbjct  817  KALQAGGFRAKMLLQVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSW  876

Query  886  YETK  889
            YE+K
Sbjct  877  YEAK  880

413) TherJR_0963 in NC_014152


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  592 bits (2235),  Expect = 4e-170, Method: Compositional matrix adjust.
 Identities = 396/906 (44%), Positives = 614/906 (68%), Gaps = 57/906 (6%)

Query  2    TQGKFIIIDGNSLVYRAFYAL----PLLKTTTGVYTNAVYGFTTMLMKVLNEEKPACLAI  57
             + K+++IDG+S+ +RAF+AL      +K  +G+ TNA+YGF  ML  +++  +P+ + +
Sbjct  3    NKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLV  62

Query  58   AFDKGKTTFRNEHFEDYKGHRKATPDELKPQFPLVKEIVRAFRIPVYEIEGYEADDIIGT  117
            AFD GKTTFR E + DYK+ R  TPDE++ QF+ ++E++ A+ I+ YE+E YEADDIIGT
Sbjct  63   AFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGT  122

Query  118  VSLKAE--EMGYETVIVTGDRDALQLVSPKTRVMLTKKGISEMELYDENKVAERYGLKPA  175
            +   AE  E+ ++  IV+GD+D +QL   +T V ++KKG++E E +    + E+ GL P 
Sbjct  123  LDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPN  182

Query  176  QIIDMKGLMGDTSDNIPGVPGIGEKTAAKLVREYGSVEELLAQ-RGTVAGKLREKLEQYA  234
            Q+ID+K+LMGD SDNIPGV  IGEKT+ KL++E+GS+E +  +  G  ++K++E+L +  
Sbjct  183  QFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDR  242

Query  235  EQALLSKKLATIIRHVPIEIDLRECVVEEPDYAKLLELGRSLEFKALTKLAQEKAPEQPE  294
            +QA+LSK LATI    PI I+L + V + PD A L ++   ++F  L K    + P++P 
Sbjct  243  DQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEPV  302

Query  295  KLSEPVDEAKQLQINGEYRQYNFDEALASITRFVEQKKDLALVLQTSNQDPWSAGILGLA  354
             +               Y+    + +  S   F  +     + ++T  ++    +I+G+A
Sbjct  303  AVIS-------------YQ----EVTNVSADLFSAED---IFYFETLRDNYHREAIIGFA  342

Query  355  WSAEPGSGGYLAGE-ELQPADKLTRILDTVLWTKGWVCFHDAKRTDILLRRLGNKPVRAG  413
            W+   G   Y + +  L ++D + ++++  + T       D KR+ +LL +LG   V ++
Sbjct  343  WG--HGEQIYASTDLSLLATDSFKQVFQKPIAT------YDFKRSKVLLSHLGIELVAPS  394

Query  414  FDTMLAAYLLDPSVSNLDLAALSIKYLGQELSPGED-Y----RSFCAQADIIL----RLV  464
            +D+ LA YLL ++V + +L++++  + +  L  ++  Y    +   ++ D++L    R V
Sbjct  395  YDARLANYLL-STVEDNELSTIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKV  453

Query  465  PVLHE-------KLAELNMLDLYFDVEMPLLHILADMEFSGVKLDKEYLEAMSVDLSTEI  517
             VL +       KL+  + LDLY ++E+PL ++LA ME+ G+K+++  L+ M+ +    I
Sbjct  454  KVLLDSKSQMLDKLTAHEQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVII  513

Query  518  DRITGDIYRLAGEEFNINSTRQLGTILFEKLGLP--VIKKTKTGYSTDVEVLETLAERHE  575
            + +T +IY +AG+EFNINS +QLG+ILFEK+ LP  + KKTKTGYST V+VLE LA    
Sbjct  514  EALTQEIYDMAGQEFNINSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAP  573

Query  576  IVARVLHYRQLVKLKSTYVDGLIPLINPVTGKVHTTFNQTVTATGRLSSTEPNLQNIPIR  635
            IVA++L+YRQ+ KL+STYV GL   I +  GK+HT + Q +T TGRLSS +PNLQNIPIR
Sbjct  574  IVAKILDYRQITKLQSTYVIGLQDYILA-DGKIHTRYVQDLTQTGRLSSVDPNLQNIPIR  632

Query  636  MEEGRRIRKAFVPSEPGWIILSADYSQIELRILAHLSGDERFVQAFRNDEDIHTRTAAEV  695
            +E+GR IRKAF PS+ + ++LS+DYSQIELR+LAH+SGDE+++ AF ++ DIHT TA  V
Sbjct  633  LEQGRLIRKAFTPSHEDAVLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRV  692

Query  696  FGVS-LEEVTGEMRSRAKAVNFGIVYGISDFGLAKNISVSRKEARQYIENYFARYAGIKK  754
            FG+    +VT++ R  AKAVNFGIVYGISDFGL++N++++RK+++ YI+ YF RY+GIK 
Sbjct  693  FGIDKAADVTANDRRNAKAVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKA  752

Query  755  YLEETVRLAREQGYVTTLLNRRRYLPDILSPNRNIRSFGERTAMNTPIQGSAADIIKLAM  814
            Y+E+ VR A+++GYV TL++RRR LPDI S N N+RSF+ERTA+N+PIQGSAADI+K+AM
Sbjct  753  YMENVVREAKDKGYVETLFKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAM  812

Query  815  VRVADCLKKEGLKARMLLQVHDELIFEAPPEELPKVTGIVRECMENTVKLTVPLKVDMKK  874
            + +   L+  G++A+MLLQVHDE+++E P +EL  +  +V++ ME +V L+VPL VD   
Sbjct  813  INLDKALQAGGFRAKMLLQVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDEST  872

Query  875  GFNWYD  880
            G +WY+
Sbjct  873  GQSWYE  878

414) Apre_1330 in NC_013171


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  591 bits (2231),  Expect = 9e-170, Method: Compositional matrix adjust.
 Identities = 388/888 (44%), Positives = 598/888 (68%), Gaps = 23/888 (2%)

Query  3    KTVMLIDGSSLIFRAFFAL----PKLTNNDGVMTNGVYGFLTMYNNAFDRYKPDYVLVAF  58
            + ++LIDGSS+ FRAFFAL     ++ N+ G+ TN++YGF  M ++   R +P  VLVAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  59   DRASKTFRHKEFEDYKGTRDKMPSELSYQFGILKDILDSLNVKYTDLDGFEADDIVGTYA  118
            D +  TFR   + DYK+ R K P E+  QF+ ++++L +L + Y +L+ +EADDI+GT  
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  119  KMAQ--EAGYESVLITGDRDYLQLVDEKIVVNLTKKGVSETKEYTVDTIKEEFGLSPKQL  176
            KMA+  E  ++  +++GD+D +QL DE+ VV+++KKGV+E  E+T   + E  GL+P+Q+
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  177  IEVKGLEGDKSDNIPGVDGIGPKKAIGFIQKYGSIEGLYDHIDEVSGKKTKQTLIDSEAI  236
            I++K+L GDKSDNIPGV  IG K ++ +++ +GS+EG+Y+HID     K K+ LI+    
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRDQ  244

Query  237  AYMSKKIGTIVTSAPVEFDLEELKVKDPDLESLREKYSKYNFNKFLEDMDGGDSPKEDKD  296
            A++SK ++TI T++P+ ++L+++  ++PD+ SL + Y   +F ++  ++ +  +      
Sbjct  245  AFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEPVAV  304

Query  297  FTYEKLENPDKLIEAIKKNKEFTFKSIYEGDRYIHSEIYKLGIKttdtptyiidpdsdFV  356
            ++Y+ + N     + +  +  F F ++   D Y +  I  ++    +      D      
Sbjct  305  ISYQEVTNVS--ADLFSAEDIFYFETL--RDNYHREAIIGFAWGHGEQIYASTDLSLLAT  360

Query  357  SKFKEIFEDEEIVKNSFDIKEDVVLLDKLGINLKLPYDDMMLMHYLIDPSRSSYDLKVLS  416
              FK++F+       ++D+K   VLL  LGI+L  P  D  L +YL+     + +L  ++
Sbjct  361  DSFKQVFQKP---IATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDN-ELSTIA  416

Query  417  QSYLDYEVKSPVDLLGKG-KKALKYQDLDFDELGNYLASGINAIEDSKEILEDKLDEYHM  475
            + + D  +     + GKG K+A+  +D+    L + LA  ++ + DSK  + DKL   + 
Sbjct  417  RIFTDISLEEDDTVYGKGAKRAVPDKDV----LLEHLARKVKVLLDSKSQMLDKLTAHEQ  472

Query  476  LDLYKEIEIKLSKVLADMEIVGFVTDKKVLedlkenidkdidkiteeiYELAGSEFNINS  535
            LDLY++IE+ L++VLA MEI G+  ++  L+D+ E+    I+ +T+EIY++AG EFNINS
Sbjct  473  LDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINS  532

Query  536  TKQLGEVLFKDLDLP--VIKKTKTGFSTNAQVLEKLRDKHQIIPKIERYRELFKLRSTYI  593
             KQLG +LF  ++LP  + KKTKTG+ST  +VLE+L     I++KI  YR++ KL+STY+
Sbjct  533  PKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYV  592

Query  594  EGLEKAIDEDGRIRSTFRQNIAATGRLSSQDPNLQNLPIKTDEGRLIRKAF-RAEEGKIL  652
             GL+  I  DG+I++ + Q+++ TGRLSS DPNLQN+PI+ ++GRLIRKAF  ++E+ +L
Sbjct  593  IGLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVL  652

Query  653  IDADYSQIELRILASLSGDRHMIDAFKEGVDIHTKTASKVFHTD-LDKVTKRQRSEAKAV  711
            + +DYSQIELR+LA +SGD H+I AF+EG DIHT TA +VF  D    VT  +R +AKAV
Sbjct  653  LSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAV  712

Query  712  NFGIIYGISDYGLSQNLNIPRKEAKEYIDNYMASYPSIKEYMDSIVEKAKEDGYVETLFK  771
            NFGI+YGISD+GLS+NL I RK++K YID Y   YP+IK YM+++V  AK+ GYVETLFK
Sbjct  713  NFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFK  772

Query  772  RRRYVPEINSRNFNVRSFGQRVALNTPIQGTAADIIKIAMIETDKNLKKAGLDAKIVLQI  831
            RRR +P+INSRNFNVRSF++R A+N+PIQG+AADI+KIAMI+ DK L+ +G+ AK++LQ+
Sbjct  773  RRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQV  832

Query  832  HDEIILEADESSKDEAIKILRESMENATDLEVPLIVDIDTGVSMYESK  879
            HDEI+LE  +       K+++++ME A DL VPL VD  TG S YE+K
Sbjct  833  HDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

415) polA-2 in NC_017297


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  589 bits (2224),  Expect = 3e-169, Method: Compositional matrix adjust.
 Identities = 407/909 (45%), Positives = 613/909 (68%), Gaps = 66/909 (7%)

Query  2    NKERLLILDSNSLLNRAFYAL----PDLMTGEGIHTNAIYGFVNMLLKMKEEINPDYIVA  57
            NK++LL++D++S+  RAF+AL      +    G+HTNAIYGF  ML  M   + P  ++ 
Sbjct  3    NKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLV  62

Query  58   AFDRKAPTFRHEEYKDYKAGRKKMPEELAQQFPIIKELLSALAINIFEIDGFEADDLIGT  117
            AFD    TFR E Y DYKAGR K P+E+ +QF+ I+E+L+AL+I  +E++ +EADD+IGT
Sbjct  63   AFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGT  122

Query  118  LSVFAEEKGI--EVYIVTGDKDALQLATDSVKVVITKKGITEKEIYDKNRMVEEFGVTPK  175
            L   AE   +  +V IV+GDKD +QL+ ++  V I+KKG++E E +    ++E  G+TP+
Sbjct  123  LDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPN  182

Query  176  EFIDVKGLMGDTSDNIPGVPGIGEKTAFKLIKEYKSIETVFENIENIKGKKLKENLHEYR  235
            +FID+K+LMGD SDNIPGV  IGEKT++KL+ E+ S+E ++E+I+ +K  K+KENL + R
Sbjct  183  QFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDR  242

Query  236  EQAIFSKKLATIICNVPIDMSLEDIKSKEEYDINKVREMFERLEFKSLMNKVGKGNEGET  295
            +QA++SK LATI    PI ++L+DI  +   D+  + + ++ ++F  L     KG  ++ 
Sbjct  243  DQAFLSKTLATINTASPITIGLDDIVYNGP-DVASLSQFYDEMDFVQLK----KGLASQM  297

Query  296  VEEEVSYKNIVSLEEFRDLKNNIIKYKENDLYLYFEL-------EDIVLFSKSRVKTLYA  348
             +E V+   ++S +E  ++  ++  +  +D++ YFE        E I+ F+ ++   +YA
Sbjct  298  PQEPVA---VISYQEVTNVSADL--FSAEDIF-YFETLRDNYHREAIIGFAWGHGEQIYA  351

Query  349  NFKDEVYRIDFEMLLNNTKEQFIEVCREMFESKEIKKITYDAKNPRTILRKLGIEFNGIK  408
            +        D+ +L   + + F    +++F+ K I   TYD K ++ +L  LGIE+ +  
Sbjct  352  S-------TDLSLL---ATDSF----KQVFQ-KPI--ATYDFKRSKVLLSHLGIELVAPS  394

Query  409  FDINLAAYLINPVRKEYEISSLASEYLFKNINREDE---FLKI--KEVNIMPNLYKVLEE  463
            +D  LA YL++ V  + E+S++A   +F +I+ E++   + K   + V     L   L  
Sbjct  395  YDARLANYLLSTVEDN-ELSTIAR--IFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLAR  451

Query  464  KIK------EQDMEEL-------LY-KVEQPLTETLSAMETEGFKVDKDILLQLEKKFKG  509
            K+K       Q ++ L       LY ++E PL++ L+ ME EG+KV++  L ++  + K 
Sbjct  452  KVKVLLDSKSQMLDKLTAHEQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKV  511

Query  510  EIESTQLEIYSMSEEEFNINSPKQLGKILFEKLDLP--VIKKTKTGYSTNAEVLDKLRDK  567
             IE+   EIY M+ +EFNINSPKQLG ILFEK++LP  + KKTKTGYST  +VL++L   
Sbjct  512  IIEALTQEIYDMAGQEFNINSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPI  571

Query  568  HPIIDKITYYRQLTKIYSTYIEGLKAAIDEDGKIHSNFNQTVTATGRLSSTEPNLQNIPI  627
             PI+ KI  YRQ+TK+ STY+ GL+  I  DGKIH+ + Q +T TGRLSS +PNLQNIPI
Sbjct  572  APIVAKILDYRQITKLQSTYVIGLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPI  631

Query  628  KYEMGREIRKVFIPNTGDSVILSADYSQIELRVLAHISDDKNMISAFNEHDDIHTKTASE  687
            + E GR IRK F P+  D+V+LS+DYSQIELRVLAHIS+D ++I+AFNE  DIHT TA  
Sbjct  632  RLEQGRLIRKAFTPSHEDAVLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMR  691

Query  688  VFKVP-IEEVTPLMRSNAKAVNFGIVYGIGDFSLSQDLNITRKEAKQYIDAYLERYPNVK  746
            VF +    +VT+  R NAKAVNFGIVYGI+DF+LS++L ITRK++K YID+Y+ERYP +K
Sbjct  692  VFGIDKAADVTANDRRNAKAVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIK  751

Query  747  LYLENIVEEAVEKGYVSTILNRRRYIKEVKSSNKIVKAAGERLAMNSPIQGSAADIIKLA  806
             Y+EN+V EA +KGYV T+++RRR + +++S N  V++ +ER A+NSPIQGSAADI+K+A
Sbjct  752  AYMENVVREAKDKGYVETLFKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIA  811

Query  807  MVNVHRKLKEDNFKSSIILQVHDELILNVHKDELEKIKALVKKEMEQVLELKVGLDVDIN  866
            M+N+++ L+ + F++ ++LQVHDE++L+V +DEL  IK LVK  ME  ++L V L VD +
Sbjct  812  MINLDKALQAGGFRAKMLLQVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDES  871

Query  867  IGNNWYEAK  875
             G++WYEAK
Sbjct  872  TGQSWYEAK  880

416) polA-2 in NC_009699


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  589 bits (2224),  Expect = 3e-169, Method: Compositional matrix adjust.
 Identities = 407/909 (45%), Positives = 613/909 (68%), Gaps = 66/909 (7%)

Query  2    NKERLLILDSNSLLNRAFYAL----PDLMTGEGIHTNAIYGFVNMLLKMKEEINPDYIVA  57
            NK++LL++D++S+  RAF+AL      +    G+HTNAIYGF  ML  M   + P  ++ 
Sbjct  3    NKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLV  62

Query  58   AFDRKAPTFRHEEYKDYKAGRKKMPEELAQQFPIIKELLSALAINIFEIDGFEADDLIGT  117
            AFD    TFR E Y DYKAGR K P+E+ +QF+ I+E+L+AL+I  +E++ +EADD+IGT
Sbjct  63   AFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGT  122

Query  118  LSVFAEEKGI--EVYIVTGDKDALQLATDSVKVVITKKGITEKEIYDKNRMVEEFGVTPK  175
            L   AE   +  +V IV+GDKD +QL+ ++  V I+KKG++E E +    ++E  G+TP+
Sbjct  123  LDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPN  182

Query  176  EFIDVKGLMGDTSDNIPGVPGIGEKTAFKLIKEYKSIETVFENIENIKGKKLKENLHEYR  235
            +FID+K+LMGD SDNIPGV  IGEKT++KL+ E+ S+E ++E+I+ +K  K+KENL + R
Sbjct  183  QFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDR  242

Query  236  EQAIFSKKLATIICNVPIDMSLEDIKSKEEYDINKVREMFERLEFKSLMNKVGKGNEGET  295
            +QA++SK LATI    PI ++L+DI  +   D+  + + ++ ++F  L     KG  ++ 
Sbjct  243  DQAFLSKTLATINTASPITIGLDDIVYNGP-DVASLSQFYDEMDFVQLK----KGLASQM  297

Query  296  VEEEVSYKNIVSLEEFRDLKNNIIKYKENDLYLYFEL-------EDIVLFSKSRVKTLYA  348
             +E V+   ++S +E  ++  ++  +  +D++ YFE        E I+ F+ ++   +YA
Sbjct  298  PQEPVA---VISYQEVTNVSADL--FSAEDIF-YFETLRDNYHREAIIGFAWGHGEQIYA  351

Query  349  NFKDEVYRIDFEMLLNNTKEQFIEVCREMFESKEIKKITYDAKNPRTILRKLGIEFNGIK  408
            +        D+ +L   + + F    +++F+ K I   TYD K ++ +L  LGIE+ +  
Sbjct  352  S-------TDLSLL---ATDSF----KQVFQ-KPI--ATYDFKRSKVLLSHLGIELVAPS  394

Query  409  FDINLAAYLINPVRKEYEISSLASEYLFKNINREDE---FLKI--KEVNIMPNLYKVLEE  463
            +D  LA YL++ V  + E+S++A   +F +I+ E++   + K   + V     L   L  
Sbjct  395  YDARLANYLLSTVEDN-ELSTIAR--IFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLAR  451

Query  464  KIK------EQDMEEL-------LY-KVEQPLTETLSAMETEGFKVDKDILLQLEKKFKG  509
            K+K       Q ++ L       LY ++E PL++ L+ ME EG+KV++  L ++  + K 
Sbjct  452  KVKVLLDSKSQMLDKLTAHEQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKV  511

Query  510  EIESTQLEIYSMSEEEFNINSPKQLGKILFEKLDLP--VIKKTKTGYSTNAEVLDKLRDK  567
             IE+   EIY M+ +EFNINSPKQLG ILFEK++LP  + KKTKTGYST  +VL++L   
Sbjct  512  IIEALTQEIYDMAGQEFNINSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPI  571

Query  568  HPIIDKITYYRQLTKIYSTYIEGLKAAIDEDGKIHSNFNQTVTATGRLSSTEPNLQNIPI  627
             PI+ KI  YRQ+TK+ STY+ GL+  I  DGKIH+ + Q +T TGRLSS +PNLQNIPI
Sbjct  572  APIVAKILDYRQITKLQSTYVIGLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPI  631

Query  628  KYEMGREIRKVFIPNTGDSVILSADYSQIELRVLAHISDDKNMISAFNEHDDIHTKTASE  687
            + E GR IRK F P+  D+V+LS+DYSQIELRVLAHIS+D ++I+AFNE  DIHT TA  
Sbjct  632  RLEQGRLIRKAFTPSHEDAVLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMR  691

Query  688  VFKVP-IEEVTPLMRSNAKAVNFGIVYGIGDFSLSQDLNITRKEAKQYIDAYLERYPNVK  746
            VF +    +VT+  R NAKAVNFGIVYGI+DF+LS++L ITRK++K YID+Y+ERYP +K
Sbjct  692  VFGIDKAADVTANDRRNAKAVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIK  751

Query  747  LYLENIVEEAVEKGYVSTILNRRRYIKEVKSSNKIVKAAGERLAMNSPIQGSAADIIKLA  806
             Y+EN+V EA +KGYV T+++RRR + +++S N  V++ +ER A+NSPIQGSAADI+K+A
Sbjct  752  AYMENVVREAKDKGYVETLFKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIA  811

Query  807  MVNVHRKLKEDNFKSSIILQVHDELILNVHKDELEKIKALVKKEMEQVLELKVGLDVDIN  866
            M+N+++ L+ + F++ ++LQVHDE++L+V +DEL  IK LVK  ME  ++L V L VD +
Sbjct  812  MINLDKALQAGGFRAKMLLQVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDES  871

Query  867  IGNNWYEAK  875
             G++WYEAK
Sbjct  872  TGQSWYEAK  880

417) polA in NC_009706


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  586 bits (2214),  Expect = 2e-168, Method: Compositional matrix adjust.
 Identities = 398/909 (44%), Positives = 607/909 (67%), Gaps = 61/909 (6%)

Query  2    SREKLLILDGHSLMNRAFYAL----PDLTNSEGTHTNAVYGFINMLLKMKKEIEPSHIVC  57
            +++KLL++DG S+  RAF+AL      + N  G HTNA+YGF  ML  M K + P+H++ 
Sbjct  3    NKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLV  62

Query  58   TFDRSAPTFRHDKYSEYKAGRKRMPPELSEQFPIVKEILELLSINIFEIDGFEADDLMGT  117
            +FD +  TFR + Y++YKAGR + P E+ EQF+ ++E+L  L+I  +E++ +EADD++GT
Sbjct  63   AFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGT  122

Query  118  LSVFAEKKGM--EVYIVTGDRDALQLATDSVKIVITKKGITQKEIYDRNKIIDDYGVTPT  175
            L   AE+  +  +V IV+GD+D +QL+ ++  + I+KKG+++ E +    +++  G+TP 
Sbjct  123  LDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPN  182

Query  176  EFIDVKGLMGDASDNIPGVPGIGEKTALKLIKEYKSIENVLCNIDNIKGKKVQENLKNYM  235
            +FID+K+LMGD SDNIPGV  IGEKT+LKL+ E+ S+E +  +ID +K  K++ENL N  
Sbjct  183  QFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDR  242

Query  236  EQAVFSKKLATIVTDVPIELDLQSIESKEQYNAEGLRKLFEKLQFKSLMDKIPKVEEQDK  295
            +QA +SK LATI T  PI ++L+ I  +   +  +L ++++ ++F  L   ++    Q+ 
Sbjct  243  DQAFLSKTLATINTASPITIGLDDIVYNGP-DVASLSQFYDEMDFVQLKKGLASQMPQEP  301

Query  296  IEVEDFQVECEVIDTLNKVHNFIDSLEAEDMKNKLLYINFKVVDENSYAKNYIDKIFINI  355
            + V  +Q   +V   L         + AED+    +Y  F  + +N Y ++ I      I
Sbjct  302  VAVISYQEVTNVSADL---------FSAEDI----FY--FETLRDN-YHREAI------I  339

Query  356  GEKNFE-IHIKEIYDENKIK--AVETAKMLFENSSLSKVSYDVKVPCSILHRMGIKLLGI  412
            G   F   H  +IY    +   A ++ K +F+++     +YD K +  +L ++GI L++ 
Sbjct  340  G---FAWGHGEQIYASTDLSLLATDSFKQVFQKPI---ATYDFKRSKVLLSHLGIELVAP  393

Query  413  EFDIKIAAYLMDPARTNYELPDIIKEYLNIEISEEREDCFIKET--------LLFSRLYS  464
             +D ++A YL+     N EL+ I + + +I + E+ +  + K +        +L+ +L  
Sbjct  394  SYDARLANYLLSTVEDN-ELSTIARIFTDISLEED-DTVYGKGAKRAVPDKDVLLEHLAR  451

Query  465  TLKKKISDSS--MDKL-------LYE-VEQPLTFVLASMECEGFKVDKDKLTEMEEKFKI  514
             +K  +   S  +DKL       LY+ +E PL+ VLA ME EG+KV++  L +M E+ K+
Sbjct  452  KVKVLLDSKSQMLDKLTAHEQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKV  511

Query  515  EIDKVQKEIYFLSEEEFNINSPKQLGKILFEKLDLP--VIKKTKTGYSTNADVLERLHGK  572
             I+ + +EIY ++ +EFNINSPKQLG ILFEK++LP  + KKTKTGYST  DVLERL   
Sbjct  512  IIEALTQEIYDMAGQEFNINSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPI  571

Query  573  HPVIEKIIYYRQLTKLYSTYIEGLKGVIEEDGKIHSNFNQTVTTTGRLSSTEPNLQNIPI  632
             P++ KI+ YRQ+TKL STY+ GL++ I  DGKIH+ + Q +T TGRLSS +PNLQNIPI
Sbjct  572  APIVAKILDYRQITKLQSTYVIGLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPI  631

Query  633  KYEMGKEIRKIFIPDNRDCVILSADYSQIELRVLAHISGDENLINAFINHNDIHTKTASE  692
            + E G+ IRK F P + D V+LS+DYSQIELRVLAHISGDE+LI AF +  DIHT TA  
Sbjct  632  RLEQGRLIRKAFTPSHEDAVLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMR  691

Query  693  VFNVP-LGEVTSTQRSNAKAVNFGIVYGIGDFSLARNLNIPRKEAKSYIDAYFEKYPKVK  751
            VF +   ++VT+ +R NAKAVNFGIVYGI+DF+L+ NL I RK++KSYID+YFE+YP +K
Sbjct  692  VFGIDKAADVTANDRRNAKAVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIK  751

Query  752  LYMNDIVKQAEKNFYVTTILNRRRFIPEIKSSNKIIKALGERFAMNTPIQGSAADIIKIA  811
             YM+++V++A  + YV T+++RRR +P+I+S N  +++++ER A+N+PIQGSAADI+KIA
Sbjct  752  AYMENVVREAKDKGYVETLFKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIA  811

Query  812  MVNVFNRLKDNNFKSKIILQVHDELVLNVYKDELKDVKDIVKEEMENVFKLKVPLEVDIS  871
            M+N+ + L+   F++K++LQVHDE+VL+V +DEL  +K +VK+ ME    L VPL VD S
Sbjct  812  MINLDKALQAGGFRAKMLLQVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDES  871

Query  872  IGDNWYQVK  880
             G++WY+ K
Sbjct  872  TGQSWYEAK  880

418) CKR_0594 in NC_011837


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  586 bits (2214),  Expect = 2e-168, Method: Compositional matrix adjust.
 Identities = 398/909 (44%), Positives = 607/909 (67%), Gaps = 61/909 (6%)

Query  2    SREKLLILDGHSLMNRAFYAL----PDLTNSEGTHTNAVYGFINMLLKMKKEIEPSHIVC  57
            +++KLL++DG S+  RAF+AL      + N  G HTNA+YGF  ML  M K + P+H++ 
Sbjct  3    NKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLV  62

Query  58   TFDRSAPTFRHDKYSEYKAGRKRMPPELSEQFPIVKEILELLSINIFEIDGFEADDLMGT  117
            +FD +  TFR + Y++YKAGR + P E+ EQF+ ++E+L  L+I  +E++ +EADD++GT
Sbjct  63   AFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGT  122

Query  118  LSVFAEKKGM--EVYIVTGDRDALQLATDSVKIVITKKGITQKEIYDRNKIIDDYGVTPT  175
            L   AE+  +  +V IV+GD+D +QL+ ++  + I+KKG+++ E +    +++  G+TP 
Sbjct  123  LDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPN  182

Query  176  EFIDVKGLMGDASDNIPGVPGIGEKTALKLIKEYKSIENVLCNIDNIKGKKVQENLKNYM  235
            +FID+K+LMGD SDNIPGV  IGEKT+LKL+ E+ S+E +  +ID +K  K++ENL N  
Sbjct  183  QFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDR  242

Query  236  EQAVFSKKLATIVTDVPIELDLQSIESKEQYNAEGLRKLFEKLQFKSLMDKIPKVEEQDK  295
            +QA +SK LATI T  PI ++L+ I  +   +  +L ++++ ++F  L   ++    Q+ 
Sbjct  243  DQAFLSKTLATINTASPITIGLDDIVYNGP-DVASLSQFYDEMDFVQLKKGLASQMPQEP  301

Query  296  IEVEDFQVECEVIDTLNKVHNFIDSLEAEDMKNKLLYINFKVVDENSYAKNYIDKIFINI  355
            + V  +Q   +V   L         + AED+    +Y  F  + +N Y ++ I      I
Sbjct  302  VAVISYQEVTNVSADL---------FSAEDI----FY--FETLRDN-YHREAI------I  339

Query  356  GEKNFE-IHIKEIYDENKIK--AVETAKMLFENSSLSKVSYDVKVPCSILHRMGIKLLGI  412
            G   F   H  +IY    +   A ++ K +F+++     +YD K +  +L ++GI L++ 
Sbjct  340  G---FAWGHGEQIYASTDLSLLATDSFKQVFQKPI---ATYDFKRSKVLLSHLGIELVAP  393

Query  413  EFDIKIAAYLMDPARTNYELPDIIKEYLNIEISEEREDCFIKET--------LLFSRLYS  464
             +D ++A YL+     N EL+ I + + +I + E+ +  + K +        +L+ +L  
Sbjct  394  SYDARLANYLLSTVEDN-ELSTIARIFTDISLEED-DTVYGKGAKRAVPDKDVLLEHLAR  451

Query  465  TLKKKISDSS--MDKL-------LYE-VEQPLTFVLASMECEGFKVDKDKLTEMEEKFKI  514
             +K  +   S  +DKL       LY+ +E PL+ VLA ME EG+KV++  L +M E+ K+
Sbjct  452  KVKVLLDSKSQMLDKLTAHEQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKV  511

Query  515  EIDKVQKEIYFLSEEEFNINSPKQLGKILFEKLDLP--VIKKTKTGYSTNADVLERLHGK  572
             I+ + +EIY ++ +EFNINSPKQLG ILFEK++LP  + KKTKTGYST  DVLERL   
Sbjct  512  IIEALTQEIYDMAGQEFNINSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPI  571

Query  573  HPVIEKIIYYRQLTKLYSTYIEGLKGVIEEDGKIHSNFNQTVTTTGRLSSTEPNLQNIPI  632
             P++ KI+ YRQ+TKL STY+ GL++ I  DGKIH+ + Q +T TGRLSS +PNLQNIPI
Sbjct  572  APIVAKILDYRQITKLQSTYVIGLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPI  631

Query  633  KYEMGKEIRKIFIPDNRDCVILSADYSQIELRVLAHISGDENLINAFINHNDIHTKTASE  692
            + E G+ IRK F P + D V+LS+DYSQIELRVLAHISGDE+LI AF +  DIHT TA  
Sbjct  632  RLEQGRLIRKAFTPSHEDAVLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMR  691

Query  693  VFNVP-LGEVTSTQRSNAKAVNFGIVYGIGDFSLARNLNIPRKEAKSYIDAYFEKYPKVK  751
            VF +   ++VT+ +R NAKAVNFGIVYGI+DF+L+ NL I RK++KSYID+YFE+YP +K
Sbjct  692  VFGIDKAADVTANDRRNAKAVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIK  751

Query  752  LYMNDIVKQAEKNFYVTTILNRRRFIPEIKSSNKIIKALGERFAMNTPIQGSAADIIKIA  811
             YM+++V++A  + YV T+++RRR +P+I+S N  +++++ER A+N+PIQGSAADI+KIA
Sbjct  752  AYMENVVREAKDKGYVETLFKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIA  811

Query  812  MVNVFNRLKDNNFKSKIILQVHDELVLNVYKDELKDVKDIVKEEMENVFKLKVPLEVDIS  871
            M+N+ + L+   F++K++LQVHDE+VL+V +DEL  +K +VK+ ME    L VPL VD S
Sbjct  812  MINLDKALQAGGFRAKMLLQVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDES  871

Query  872  IGDNWYQVK  880
             G++WY+ K
Sbjct  872  TGQSWYEAK  880

419) polA in NC_010516


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  585 bits (2208),  Expect = 6e-168, Method: Compositional matrix adjust.
 Identities = 409/909 (45%), Positives = 611/909 (68%), Gaps = 66/909 (7%)

Query  2    NKERLLILDSNSLLNRAFYAL----PDLMTGEGIHTNAIYGFVNMLLKMKEEIKPDYIVA  57
            NK++LL++D++S+  RAF+AL      +    G+HTNAIYGF  ML  M   ++P  ++ 
Sbjct  3    NKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLV  62

Query  58   AFDRKAPTFRHEEYKDYKAGRKKMPEELAQQFPIVKELLSALAINIFEIDGFEADDLIGT  117
            AFD    TFR E Y DYKAGR K P+E+ +QF+ ++E+L+AL+I  +E++ +EADD+IGT
Sbjct  63   AFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGT  122

Query  118  LSVFAEEKGI--EVYIVTGDKDALQLATDNVKVVITKKGITEKEIYDKNRMMEEFGVTPK  175
            L   AE   +  +V IV+GDKD +QL+ +N  V I+KKG++E E +    +ME  G+TP+
Sbjct  123  LDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPN  182

Query  176  EFIDVKGLMGDTSDNIPGVPGIGEKTAFKLIKEYKSIETVLENIENIKGKKLKENLHEYR  235
            +FID+K+LMGD SDNIPGV  IGEKT++KL+ E+ S+E + E+I+ +K  K+KENL + R
Sbjct  183  QFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDR  242

Query  236  EQAIFSKKLATIICNVPIDMSLEDIKSKEEYDINKVRKMFERLEFKSLMNKVGKSDeeet  295
            +QA++SK LATI    PI ++L+DI  +   D+  + + ++ ++F  L + ++ S+  + 
Sbjct  243  DQAFLSKTLATINTASPITIGLDDIVYNGP-DVASLSQFYDEMDFVQLKKGLA-SQMPQE  300

Query  296  veeevSYKNIVSLEEFKDLKNNIIKYKENDLYLYFEL-------EDIVLFSKSRIKTLYA  348
                +SY+++ ++    DL      +  +D++ YFE        E I+ F+ ++   +YA
Sbjct  301  PVAVISYQEVTNVSA--DL------FSAEDIF-YFETLRDNYHREAIIGFAWGHGEQIYA  351

Query  349  NFKDEVYRIDFEMLLNNTKEQFIEVCKEMFEGKEIKKITYDAKNPRTILRKLGIEFNGIK  408
            +        D+ +L   + + F    K++F+ K I   TYD K ++ +L  LGIE+ +  
Sbjct  352  S-------TDLSLL---ATDSF----KQVFQ-KPI--ATYDFKRSKVLLSHLGIELVAPS  394

Query  409  FDINLAAYLIDPVRKEYEISSLASEYLFKNINREDE---FLKI--KEVNIMPNLYKVLEE  463
            +D  LA YL+  V  + E+S++A   +F +I+ E++   + K   + V     L   L  
Sbjct  395  YDARLANYLLSTVEDN-ELSTIAR--IFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLAR  451

Query  464  KIK------EQDMEEL-------LY-KVEQPLTETLSAMETEGFKVDKDILLQLEKKFKG  509
            K+K       Q ++ L       LY ++E PL++ L+ ME EG+KV++  L ++  + K 
Sbjct  452  KVKVLLDSKSQMLDKLTAHEQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKV  511

Query  510  EIESTQLEIYSMSEEEFNINSPKQLGKILFEKLDLP--VIKKTKTGYSTNAEVLDKLRDK  567
             IE+   EIY M+ +EFNINSPKQLG ILFEK++LP  + KKTKTGYST  +VL++L   
Sbjct  512  IIEALTQEIYDMAGQEFNINSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPI  571

Query  568  HPIIDKITYYRQLTKIYSTYIEGLKAAIDEDGKIHSNFNQTVTATGRLSSTEPNLQNIPI  627
             PI+ KI  YRQ+TK+ STY+ GL+  I  DGKIH+ + Q +T TGRLSS +PNLQNIPI
Sbjct  572  APIVAKILDYRQITKLQSTYVIGLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPI  631

Query  628  KYEMGREIRKVFIPNTGDSVILSADYSQIELRVLAHISDDKNMISAFNEHDDIHTKTASE  687
            + E GR IRK F P+  D+V+LS+DYSQIELRVLAHIS+D ++I+AFNE  DIHT TA  
Sbjct  632  RLEQGRLIRKAFTPSHEDAVLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMR  691

Query  688  VFKVP-IEEVTPLMRSNAKAVNFGIVYGIGDFSLSQDLNITRKEAKQYIDAYLERYPNVK  746
            VF +    +VT+  R NAKAVNFGIVYGI+DF+LS++L ITRK++K YID+Y+ERYP +K
Sbjct  692  VFGIDKAADVTANDRRNAKAVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIK  751

Query  747  LYLENIVEEAVEKGYVSTILNRRRYIKEVKSSNKIVKAAGERLAMNSPIQGSAADIIKLA  806
             Y+EN+V EA +KGYV T+++RRR + +++S N  V++ +ER A+NSPIQGSAADI+K+A
Sbjct  752  AYMENVVREAKDKGYVETLFKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIA  811

Query  807  MVNVHKKLKEDNFKSSIILQVHDELILNVHKDELEKIKALVKKEMEQVLELKVGLDVDIN  866
            M+N++K L+ + F++ ++LQVHDE++L+V +DEL  IK LVK  ME  ++L V L VD +
Sbjct  812  MINLDKALQAGGFRAKMLLQVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDES  871

Query  867  IGNNWYEAK  875
             G++WYEAK
Sbjct  872  TGQSWYEAK  880

420) CbC4_0864 in NC_015425


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  582 bits (2197),  Expect = 4e-167, Method: Compositional matrix adjust.
 Identities = 393/907 (44%), Positives = 607/907 (67%), Gaps = 56/907 (6%)

Query  2    NKERLLILDGHSLMYRAFFAL----PPLTNKEGIHTNAIYGFIKMLLKMKEEIKPNYIVT  57
            NK++LL++DG S+ +RAFFAL      + N  G+HTNAIYGF  ML  M   ++P  ++ 
Sbjct  3    NKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLV  62

Query  58   AFDKKAPTFRHKEYEDYKAGRAKMPSELNEQFPIVKEILNKLAINIFEIDGFEADDLIGT  117
            AFD    TFR   Y DYKAGRAK P E+ EQF+ ++E+L  L+I  +E++ +EADD+IGT
Sbjct  63   AFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGT  122

Query  118  LSQFAEEKGI--EVYIVTGDKDALQLATDNVKIVINKKGMSEKEIYDRNRMIEEYEVTPT  175
            L + AE   +  +V IV+GDKD +QL+ +N  + I+KKG++E E +    ++E   +TP 
Sbjct  123  LDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPN  182

Query  176  QFIDVKGLMGDKSDNIPGVPGIGTKTAFKLIKEYGSIENVLENVENISGKKMKQNLIEYR  235
            QFID+K+LMGDKSDNIPGV  IG KT++KL+ E+GS+E + E+++ +   KMK+NLI+ R
Sbjct  183  QFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDR  242

Query  236  EQAIFSKKLATICTNVPIEIDLEEIKSKENYDIEGVRQLFESLGFKSLIQNIASSDNQee  295
            +QA++SK LATI T  PI I+L++I  +   D+ ++ Q+++ ++F  L + +AS   Q  
Sbjct  243  DQAFLSKTLATINTASPITIGLDDIVYNGP-DVASLSQFYDEMDFVQLKKGLASQMPQ--  299

Query  296  senneekieeinikvessnieTVDELSNLLSDIKDTVYFQVECVNENVYSKIEFNTIYIR  355
                          V   + + V ++S  L    D  YF  E + +N Y +  +  +   
Sbjct  300  ------------EPVAVISYQEVTNVSADLFSAEDIFYF--ETLRDN-YHREAIIGFAWG  344

Query  356  NEEKIYV-VNINKIKNENYDKYLELIKKLFEDENIKKISHDIKNIYVILRKYDIDAKNFS  414
            + E+IY   +++ +  +++       K++F+       + D+K   V+L   +I+    S
Sbjct  345  HGEQIYASTDLSLLATDSF-------KQVFQKPI---ATYDFKRSKVLLSHLGIELVAPS  394

Query  415  FDTKIAAYLLQPSKSDYILRDI--ILEKLSINIHESDEESKIKETYCIKEI-YEKLQKEI  471
            +D+++A YLL     +  L  I  I+  +S++ +++      K +   K++  E L + +
Sbjct  395  YDARLANYLLSTVEDN-ELSTIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKV  453

Query  472  ------KSANME--------ELFYNVELPLVKVLASMECEGFKIDKDRLTEIGEKFKVKI  517
                  KS  ++        +L+ N+ELPL +VLA ME EG+K+++  L +++E+ KV I
Sbjct  454  KVLLDSKSQMLDKLTAHEQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVII  513

Query  518  ETLEKEIHEFADEDFNIKSPKQLGKILFEKLDLP--VIKKTKTGYSTNAEVLEKLKDSHP  575
            E+L +EI + A+++FNI+SPKQLG ILFEK++LP  + KKTKTGYST  +VLE+L    P
Sbjct  514  EALTQEIYDMAGQEFNINSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAP  573

Query  576  IISKIIEYRQITKLDSTYVEGLKHVIDEDGKIHSSFNQTVTTTGRLSSTEPNLQNIPIKY  635
            I++KI++YRQITKL+STYV GL++ I  DGKIH+ + Q +T TGRLSS +PNLQNIPI+ 
Sbjct  574  IVAKILDYRQITKLQSTYVIGLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRL  633

Query  636  EMGREIRKVFVPNNEESVIFSADYSQIELRVLAHIANDEKLIDAFKHHKDIHTITASEVF  695
            E GR IRK F P++E++V++S+DYSQIELRVLAHI+ DE LI AF++  DIHT TA  VF
Sbjct  634  EQGRLIRKAFTPSHEDAVLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVF  693

Query  696  KVH-IDEVTPLMRSNAKAVNFGIVYGIGAFSLSKDINVSRKEAKEYIDTYFSRYPNVKKY  754
             ++   +VT+  R NAKAVNFGIVYGI+ F+LS+++ ++RK++K YIDTYF RYP +K Y
Sbjct  694  GIDKAADVTANDRRNAKAVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAY  753

Query  755  IDEIISKAEQDGFVTTIMNRKRYIPEVQSRNKIVRSFGERLAMNTPIQGSAADVIKLAMV  814
            +++++  A + G+V T+ +R+R +P+++SRN  VRSF+ER A+N+PIQGSAAD++K+AM+
Sbjct  754  MENVVREAKDKGYVETLFKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMI  813

Query  815  HVYEELIKRNLKSTLILQVHDELILNVYKDELEEVKQMVVDKMEGVMNLLVPLEADVNVG  874
            ++   L    +++ ++LQVHDE++L+V +DEL  +K++V D ME+ ++L VPL  D + G
Sbjct  814  NLDKALQAGGFRAKMLLQVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTG  873

Query  875  TTWYEAK  881
             +WYEAK
Sbjct  874  QSWYEAK  880

421) Mahau_1179 in NC_015520


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  578 bits (2184),  Expect = 5e-166, Method: Compositional matrix adjust.
 Identities = 382/896 (43%), Positives = 596/896 (67%), Gaps = 68/896 (7%)

Query  3    DKIMLIDGNSLLNRAFYAL----PMLTNAEGQYTNGVYGFLTMLYKVMEQEKPTHIAVAF  58
            +K++LIDG+S+  RAF+AL      + N  G  TN++YGF  ML  +M + +PTH+ VAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  59   DRKAPTFRHEQYDGYKAKRTGMPDEMASQLPVLKEVLTAMNIRIFEMDGYEADDILGTLA  118
            D    TFR E Y +YKA R+  PDE   Q++ ++E+LTA+ I  +E++ YEADDI+GTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  119  NMAHQKGM--EVVLVTGDRDALQLVKPDVKVIITKRGITDVEVCDEQAITQRYGIKPEQL  176
            +MA++  +  +V +V+GD+D +QL   +  V I+K+G+++ E      + ++ G+ P+Q+
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  177  IDVKGLMGDASDNIPGVPGIGEKTALRLIKQFGSLESVLEHIDDVSGDKLKKLLTEYREQ  236
            ID+K+LMGD SDNIPGV  IGEKT+L+L+ +FGSLE++ EHID+    K+K  L + R+Q
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRDQ  244

Query  237  AIMSKQLGAIQCCVPIDDDLDKCRCKGPDAVKLKEIYQRLDF----KSLLSKIPQNNDEE  292
            A++SK L++I+   PI  +LD    +GPD   L ++Y+ +DF    K+L S++PQ     
Sbjct  245  AFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQ-----  299

Query  293  FADKDPIGSDVYNVGDDDIEQLGKDLSNVNELCVYS--------NDVLSLS-EDELKVY-  342
                +P++   Y    +++ +++ DL + +++  +         + +++++  +  ++Y 
Sbjct  300  ----EPVAVISY----QEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYA  351

Query  343  NISVKQSVPDIVAAVLSNPKVHKHVYDAKRLIVSMNKSHINVKGIDFDAMIAAYLLDPSQ  402
            +  +     D    V+ +P      YD KR  V ++   I++ +  +DA +A YLL   +
Sbjct  352  STDLSLLATDSFKQVFQKPIA---TYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVE  408

Query  403  SNYDIKRLVKQYLEI--DDDAASHA--------------GYLWRLMNI-------MLPQI  439
             N ++  + + + +I  ++D +  +                L R +++       ML ++
Sbjct  409  DN-ELSTIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKL  467

Query  440  KENEMNALFYDIEMPLTRVLADMEINGFTVDVQMLKELADDFERMIDGLTKEIYALAGEE  499
              +E   L+ +IE+PL+ VLA MEI+G+ V+   L+++A++   +I++LT+EIY +AG+E
Sbjct  468  TAHEQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQE  527

Query  500  FNINSPKQLGAILFEKLKLPV--GKKTKTGYSTDIEVLKQLQLQHDIVPKIIDYRQLTKL  557
            FNINSPKQLG+ILFEK++LP+   KKTKTGYST ++VL +L     IV+KI+DYRQ+TKL
Sbjct  528  FNINSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKL  587

Query  558  KSTYIDGLMN--MADPITHKIHSKFNQTVTVTGRISSTEPNLQNIPVKTELGHQIRKAFV  615
            +STY+ GL +  +AD    KIH+++ Q +T TGR+SS +PNLQNIP++ E G+ IRKAF 
Sbjct  588  QSTYVIGLQDYILADG---KIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFT  644

Query  616  PSSSDYLLLDADYSQIELRVLAHMSQDQNMIDAFLKGQDIHARTASEVFGIP-LEQVTPL  674
            PS  D +LL +DYSQIELRVLAH+S D+++I AF  G DIH+ TA  VFGI    +VT+ 
Sbjct  645  PSHEDAVLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTAN  704

Query  675  MRSRAKAVNFGIVYGISDFGLARNIGISRSEAKQYIEQYFARYNGVRRFMDETIQFAKKH  734
             R  AKAVNFGIVYGISDFGL+ N+GI+R ++K YI+ YF RY G++ +M++ ++ AK  
Sbjct  705  DRRNAKAVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDK  764

Query  735  GYVTTMFKRRRYLPELASSNRTVRSFGERAAMNTPIQGTAADIIKKAMVDIYNALKENEY  794
            GYV T+FKRRR LP++ S N  VRSF+ER+A+N+PIQG+AADI+K AM+++ +AL+   +
Sbjct  765  GYVETLFKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGF  824

Query  795  RSKLILQVHDELIIEVHRDEVDEIRDLVKDKMEGVVKMDVPLVADIHVGENWYDAK  850
            R+K++LQVHDE+++EV  DE+  I+ LVKD ME+ V + VPL  D   G++WY+AK
Sbjct  825  RAKMLLQVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

422) polA in NC_009697


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  578 bits (2181),  Expect = 7e-166, Method: Compositional matrix adjust.
 Identities = 404/910 (45%), Positives = 606/910 (67%), Gaps = 68/910 (7%)

Query  2    NKERLLILDSNSLLNRAFYAL----PDLMTGEGIHTNAIYGFVNMLLKMKEEINPDYIVA  57
            NK++LL++D++S+  RAF+AL      +    G+HTNAIYGF  ML  M   + P  ++ 
Sbjct  3    NKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLV  62

Query  58   AFDRKAPTFRHEEYKDYKAGRKKMPEELAQQFPIVKELLSALAINIFEIDGFEADDLIGT  117
            AFD    TFR E Y DYKAGR K P+E+ +QF+ ++E+L+AL+I  +E++ +EADD+IGT
Sbjct  63   AFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGT  122

Query  118  LSVFAEEKGI--EVYIVTGDKDALQLATDNVKVVITKKGITEKEIYDKNRMVEEFGVTPK  175
            L   AE   +  +V IV+GDKD +QL+ +N  V I+KKG++E E +    ++E  G+TP+
Sbjct  123  LDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPN  182

Query  176  EFIDVKGLMGDTSDNIPGVPGIGEKTAFKLIKEYKSIETVLENIENIKGKKLKENLHEYR  235
            +FID+K+LMGD SDNIPGV  IGEKT++KL+ E+ S+E + E+I+ +K  K+KENL + R
Sbjct  183  QFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDR  242

Query  236  EQAIFSKKLATIICNVPIDMSLEDIKSKEEYDINKVREMFERLEFKSLMNKVGKSDeeet  295
            +QA++SK LATI    PI ++L+DI  +   D+  + + ++ ++F  L + ++ S+  + 
Sbjct  243  DQAFLSKTLATINTASPITIGLDDIVYNGP-DVASLSQFYDEMDFVQLKKGLA-SQMPQE  300

Query  296  veeevSYKNIVSLEEFKDLKNNIIKYKENDLYLYFEL-------EDIVLFSKSRVKTLYA  348
                +SY+++ ++    DL      +  +D++ YFE        E I+ F+ ++   +YA
Sbjct  301  PVAVISYQEVTNVSA--DL------FSAEDIF-YFETLRDNYHREAIIGFAWGHGEQIYA  351

Query  349  NFKDEVYRIDFEMLIKNT-KEQFIEVCkeifeskeikkiTYDAKNPRTILRKLGIEFNGI  407
            +        D+ +L  ++ K+ F           +    TYD K ++ +L  LGIE+ + 
Sbjct  352  S-------TDLSLLATDSFKQVF-----------QKPIATYDFKRSKVLLSHLGIELVAP  393

Query  408  KFDINLAAYLIDPVRKEYEISSLASEYLFKNINREDE---FLKI--KEVNIMPNLYKVLE  462
             +D  LA YL+  V  + E+S++A   +F +I+ E++   + K   + V     L   L 
Sbjct  394  SYDARLANYLLSTVEDN-ELSTIAR--IFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLA  450

Query  463  EKIK------EQDMEEL-------LY-KVEQPLTETLSAMETEGFKVDKDILLQLEKKFK  508
             K+K       Q ++ L       LY ++E PL++ L+ ME EG+KV++  L ++  + K
Sbjct  451  RKVKVLLDSKSQMLDKLTAHEQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNK  510

Query  509  GEIESTQLEIYSMSEEEFNINSPKQLGKILFEKLDLP--VIKKTKTGYSTNAEVLDKLRD  566
              IE+   EIY M+ +EFNINSPKQLG ILFEK++LP  + KKTKTGYST  +VL++L  
Sbjct  511  VIIEALTQEIYDMAGQEFNINSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAP  570

Query  567  KHPIIDKITYYRQLTKIYSTYIEGLKAAIDEDGKIHSNFNQTVTATGRLSSTEPNLQNIP  626
              PI+ KI  YRQ+TK+ STY+ GL+  I  DGKIH+ + Q +T TGRLSS +PNLQNIP
Sbjct  571  IAPIVAKILDYRQITKLQSTYVIGLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIP  630

Query  627  IKYEMGREIRKVFIPNTGDSVILSADYSQIELRVLAHISDDKNMISAFNEHDDIHTKTAS  686
            I+ E GR IRK F P+  D+V+LS+DYSQIELRVLAHIS+D ++I+AFNE  DIHT TA 
Sbjct  631  IRLEQGRLIRKAFTPSHEDAVLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAM  690

Query  687  EVFKVP-IEEVTPLMRGNAKAVNFGIVYGIGDFSLSQDLNITRKEAKQYIDAYLERYPNV  745
             VF +    +VT+  R NAKAVNFGIVYGI+DF+LS++L ITRK++K YID+Y+ERYP +
Sbjct  691  RVFGIDKAADVTANDRRNAKAVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGI  750

Query  746  KLYLENIVEEAIEKGYVSTILNRRRYIKEVKSSNKIVKAAGERLAMNSPIQGSAADIIKL  805
            K Y+EN+V EA +KGYV T+++RRR + +++S N  V++ +ER A+NSPIQGSAADI+K+
Sbjct  751  KAYMENVVREAKDKGYVETLFKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKI  810

Query  806  AMVNVHRKLKEDNFKSSIILQVHDELILNVHKDELEKIKALVKKEMEQVLELKVGLDVDI  865
            AM+N+++ L+ + F++ ++LQVHDE++L+V +DEL  IK LVK  ME  ++L V L VD 
Sbjct  811  AMINLDKALQAGGFRAKMLLQVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDE  870

Query  866  NIGNNWYEAK  875
            + G++WYEAK
Sbjct  871  STGQSWYEAK  880

423) polA in NC_009495


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  578 bits (2181),  Expect = 7e-166, Method: Compositional matrix adjust.
 Identities = 404/910 (45%), Positives = 606/910 (67%), Gaps = 68/910 (7%)

Query  2    NKERLLILDSNSLLNRAFYAL----PDLMTGEGIHTNAIYGFVNMLLKMKEEINPDYIVA  57
            NK++LL++D++S+  RAF+AL      +    G+HTNAIYGF  ML  M   + P  ++ 
Sbjct  3    NKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLV  62

Query  58   AFDRKAPTFRHEEYKDYKAGRKKMPEELAQQFPIVKELLSALAINIFEIDGFEADDLIGT  117
            AFD    TFR E Y DYKAGR K P+E+ +QF+ ++E+L+AL+I  +E++ +EADD+IGT
Sbjct  63   AFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGT  122

Query  118  LSVFAEEKGI--EVYIVTGDKDALQLATDNVKVVITKKGITEKEIYDKNRMVEEFGVTPK  175
            L   AE   +  +V IV+GDKD +QL+ +N  V I+KKG++E E +    ++E  G+TP+
Sbjct  123  LDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPN  182

Query  176  EFIDVKGLMGDTSDNIPGVPGIGEKTAFKLIKEYKSIETVLENIENIKGKKLKENLHEYR  235
            +FID+K+LMGD SDNIPGV  IGEKT++KL+ E+ S+E + E+I+ +K  K+KENL + R
Sbjct  183  QFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDR  242

Query  236  EQAIFSKKLATIICNVPIDMSLEDIKSKEEYDINKVREMFERLEFKSLMNKVGKSDeeet  295
            +QA++SK LATI    PI ++L+DI  +   D+  + + ++ ++F  L + ++ S+  + 
Sbjct  243  DQAFLSKTLATINTASPITIGLDDIVYNGP-DVASLSQFYDEMDFVQLKKGLA-SQMPQE  300

Query  296  veeevSYKNIVSLEEFKDLKNNIIKYKENDLYLYFEL-------EDIVLFSKSRVKTLYA  348
                +SY+++ ++    DL      +  +D++ YFE        E I+ F+ ++   +YA
Sbjct  301  PVAVISYQEVTNVSA--DL------FSAEDIF-YFETLRDNYHREAIIGFAWGHGEQIYA  351

Query  349  NFKDEVYRIDFEMLIKNT-KEQFIEVCkeifeskeikkiTYDAKNPRTILRKLGIEFNGI  407
            +        D+ +L  ++ K+ F           +    TYD K ++ +L  LGIE+ + 
Sbjct  352  S-------TDLSLLATDSFKQVF-----------QKPIATYDFKRSKVLLSHLGIELVAP  393

Query  408  KFDINLAAYLIDPVRKEYEISSLASEYLFKNINREDE---FLKI--KEVNIMPNLYKVLE  462
             +D  LA YL+  V  + E+S++A   +F +I+ E++   + K   + V     L   L 
Sbjct  394  SYDARLANYLLSTVEDN-ELSTIAR--IFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLA  450

Query  463  EKIK------EQDMEEL-------LY-KVEQPLTETLSAMETEGFKVDKDILLQLEKKFK  508
             K+K       Q ++ L       LY ++E PL++ L+ ME EG+KV++  L ++  + K
Sbjct  451  RKVKVLLDSKSQMLDKLTAHEQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNK  510

Query  509  GEIESTQLEIYSMSEEEFNINSPKQLGKILFEKLDLP--VIKKTKTGYSTNAEVLDKLRD  566
              IE+   EIY M+ +EFNINSPKQLG ILFEK++LP  + KKTKTGYST  +VL++L  
Sbjct  511  VIIEALTQEIYDMAGQEFNINSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAP  570

Query  567  KHPIIDKITYYRQLTKIYSTYIEGLKAAIDEDGKIHSNFNQTVTATGRLSSTEPNLQNIP  626
              PI+ KI  YRQ+TK+ STY+ GL+  I  DGKIH+ + Q +T TGRLSS +PNLQNIP
Sbjct  571  IAPIVAKILDYRQITKLQSTYVIGLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIP  630

Query  627  IKYEMGREIRKVFIPNTGDSVILSADYSQIELRVLAHISDDKNMISAFNEHDDIHTKTAS  686
            I+ E GR IRK F P+  D+V+LS+DYSQIELRVLAHIS+D ++I+AFNE  DIHT TA 
Sbjct  631  IRLEQGRLIRKAFTPSHEDAVLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAM  690

Query  687  EVFKVP-IEEVTPLMRGNAKAVNFGIVYGIGDFSLSQDLNITRKEAKQYIDAYLERYPNV  745
             VF +    +VT+  R NAKAVNFGIVYGI+DF+LS++L ITRK++K YID+Y+ERYP +
Sbjct  691  RVFGIDKAADVTANDRRNAKAVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGI  750

Query  746  KLYLENIVEEAIEKGYVSTILNRRRYIKEVKSSNKIVKAAGERLAMNSPIQGSAADIIKL  805
            K Y+EN+V EA +KGYV T+++RRR + +++S N  V++ +ER A+NSPIQGSAADI+K+
Sbjct  751  KAYMENVVREAKDKGYVETLFKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKI  810

Query  806  AMVNVHRKLKEDNFKSSIILQVHDELILNVHKDELEKIKALVKKEMEQVLELKVGLDVDI  865
            AM+N+++ L+ + F++ ++LQVHDE++L+V +DEL  IK LVK  ME  ++L V L VD 
Sbjct  811  AMINLDKALQAGGFRAKMLLQVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDE  870

Query  866  NIGNNWYEAK  875
            + G++WYEAK
Sbjct  871  STGQSWYEAK  880

424) polA in NC_009698


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  578 bits (2181),  Expect = 7e-166, Method: Compositional matrix adjust.
 Identities = 404/910 (45%), Positives = 606/910 (67%), Gaps = 68/910 (7%)

Query  2    NKERLLILDSNSLLNRAFYAL----PDLMTGEGIHTNAIYGFVNMLLKMKEEINPDYIVA  57
            NK++LL++D++S+  RAF+AL      +    G+HTNAIYGF  ML  M   + P  ++ 
Sbjct  3    NKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLV  62

Query  58   AFDRKAPTFRHEEYKDYKAGRKKMPEELAQQFPIVKELLSALAINIFEIDGFEADDLIGT  117
            AFD    TFR E Y DYKAGR K P+E+ +QF+ ++E+L+AL+I  +E++ +EADD+IGT
Sbjct  63   AFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGT  122

Query  118  LSVFAEEKGI--EVYIVTGDKDALQLATDNVKVVITKKGITEKEIYDKNRMVEEFGVTPK  175
            L   AE   +  +V IV+GDKD +QL+ +N  V I+KKG++E E +    ++E  G+TP+
Sbjct  123  LDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPN  182

Query  176  EFIDVKGLMGDTSDNIPGVPGIGEKTAFKLIKEYKSIETVLENIENIKGKKLKENLHEYR  235
            +FID+K+LMGD SDNIPGV  IGEKT++KL+ E+ S+E + E+I+ +K  K+KENL + R
Sbjct  183  QFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDR  242

Query  236  EQAIFSKKLATIICNVPIDMSLEDIKSKEEYDINKVREMFERLEFKSLMNKVGKSDeeet  295
            +QA++SK LATI    PI ++L+DI  +   D+  + + ++ ++F  L + ++ S+  + 
Sbjct  243  DQAFLSKTLATINTASPITIGLDDIVYNGP-DVASLSQFYDEMDFVQLKKGLA-SQMPQE  300

Query  296  veeevSYKNIVSLEEFKDLKNNIIKYKENDLYLYFEL-------EDIVLFSKSRVKTLYA  348
                +SY+++ ++    DL      +  +D++ YFE        E I+ F+ ++   +YA
Sbjct  301  PVAVISYQEVTNVSA--DL------FSAEDIF-YFETLRDNYHREAIIGFAWGHGEQIYA  351

Query  349  NFKDEVYRIDFEMLIKNT-KEQFIEVCkeifeskeikkiTYDAKNPRTILRKLGIEFNGI  407
            +        D+ +L  ++ K+ F           +    TYD K ++ +L  LGIE+ + 
Sbjct  352  S-------TDLSLLATDSFKQVF-----------QKPIATYDFKRSKVLLSHLGIELVAP  393

Query  408  KFDINLAAYLIDPVRKEYEISSLASEYLFKNINREDE---FLKI--KEVNIMPNLYKVLE  462
             +D  LA YL+  V  + E+S++A   +F +I+ E++   + K   + V     L   L 
Sbjct  394  SYDARLANYLLSTVEDN-ELSTIAR--IFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLA  450

Query  463  EKIK------EQDMEEL-------LY-KVEQPLTETLSAMETEGFKVDKDILLQLEKKFK  508
             K+K       Q ++ L       LY ++E PL++ L+ ME EG+KV++  L ++  + K
Sbjct  451  RKVKVLLDSKSQMLDKLTAHEQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNK  510

Query  509  GEIESTQLEIYSMSEEEFNINSPKQLGKILFEKLDLP--VIKKTKTGYSTNAEVLDKLRD  566
              IE+   EIY M+ +EFNINSPKQLG ILFEK++LP  + KKTKTGYST  +VL++L  
Sbjct  511  VIIEALTQEIYDMAGQEFNINSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAP  570

Query  567  KHPIIDKITYYRQLTKIYSTYIEGLKAAIDEDGKIHSNFNQTVTATGRLSSTEPNLQNIP  626
              PI+ KI  YRQ+TK+ STY+ GL+  I  DGKIH+ + Q +T TGRLSS +PNLQNIP
Sbjct  571  IAPIVAKILDYRQITKLQSTYVIGLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIP  630

Query  627  IKYEMGREIRKVFIPNTGDSVILSADYSQIELRVLAHISDDKNMISAFNEHDDIHTKTAS  686
            I+ E GR IRK F P+  D+V+LS+DYSQIELRVLAHIS+D ++I+AFNE  DIHT TA 
Sbjct  631  IRLEQGRLIRKAFTPSHEDAVLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAM  690

Query  687  EVFKVP-IEEVTPLMRGNAKAVNFGIVYGIGDFSLSQDLNITRKEAKQYIDAYLERYPNV  745
             VF +    +VT+  R NAKAVNFGIVYGI+DF+LS++L ITRK++K YID+Y+ERYP +
Sbjct  691  RVFGIDKAADVTANDRRNAKAVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGI  750

Query  746  KLYLENIVEEAIEKGYVSTILNRRRYIKEVKSSNKIVKAAGERLAMNSPIQGSAADIIKL  805
            K Y+EN+V EA +KGYV T+++RRR + +++S N  V++ +ER A+NSPIQGSAADI+K+
Sbjct  751  KAYMENVVREAKDKGYVETLFKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKI  810

Query  806  AMVNVHRKLKEDNFKSSIILQVHDELILNVHKDELEKIKALVKKEMEQVLELKVGLDVDI  865
            AM+N+++ L+ + F++ ++LQVHDE++L+V +DEL  IK LVK  ME  ++L V L VD 
Sbjct  811  AMINLDKALQAGGFRAKMLLQVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDE  870

Query  866  NIGNNWYEAK  875
            + G++WYEAK
Sbjct  871  STGQSWYEAK  880

425) H04402_03109 in NC_017299


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  577 bits (2178),  Expect = 1e-165, Method: Compositional matrix adjust.
 Identities = 403/909 (45%), Positives = 606/909 (67%), Gaps = 66/909 (7%)

Query  2    NKERLLILDSNSLLNRAFYAL----PDLMTGEGIHTNAIYGFVNMLLKMKEEINPDYIVA  57
            NK++LL++D++S+  RAF+AL      +    G+HTNAIYGF  ML  M   + P  ++ 
Sbjct  3    NKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLV  62

Query  58   AFDRKAPTFRHEEYKDYKAGRKKMPEELAQQFPIVKELLSALAINIFEIDGFEADDLIGT  117
            AFD    TFR E Y DYKAGR K P+E+ +QF+ ++E+L+AL+I  +E++ +EADD+IGT
Sbjct  63   AFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGT  122

Query  118  LSVFAEEKGI--EVYIVTGDKDALQLATDNVKVVITKKGITEKEIYDKNRMIEEFGVTPK  175
            L   AE   +  +V IV+GDKD +QL+ +N  V I+KKG++E E +    ++E  G+TP+
Sbjct  123  LDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPN  182

Query  176  EFIDVKGLMGDTSDNIPGVPGIGEKTAFKLIKEYKSIETVLENIENIKGKKLKENLHEYR  235
            +FID+K+LMGD SDNIPGV  IGEKT++KL+ E+ S+E + E+I+ +K  K+KENL + R
Sbjct  183  QFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDR  242

Query  236  EQAIFSKKLATIICNVPIDMSLEDIKSKEEYDINKVRKMFERLEFKSLMNKVGKSDeeet  295
            +QA++SK LATI    PI ++L+DI  +   D+  + + ++ ++F  L + ++ S+  + 
Sbjct  243  DQAFLSKTLATINTASPITIGLDDIVYNGP-DVASLSQFYDEMDFVQLKKGLA-SQMPQE  300

Query  296  veeevSYKNIVSLEEFKDLKNNIIKYKENDLYLYFEL-------EDIVLFSKSRVKTLYA  348
                +SY+++ ++    DL      +  +D++ YFE        E I+ F+ ++   +YA
Sbjct  301  PVAVISYQEVTNVSA--DL------FSAEDIF-YFETLRDNYHREAIIGFAWGHGEQIYA  351

Query  349  NFKDEVYKIDFEMLLNNTKEQFIEVCkeifeskeikkiTYDAKNPRTILRKLGIEFNGIE  408
            +        D+ +L   + + F +V        +    TYD K ++ +L  LGIE+ +  
Sbjct  352  S-------TDLSLL---ATDSFKQV-------FQKPIATYDFKRSKVLLSHLGIELVAPS  394

Query  409  FDINLAAYLIDPVRKEYEISSLASEYLFKNINREDE---FLRI--KEVNIMPNLYKVLEE  463
            +D  LA YL+  V  + E+S++A   +F +I+ E++   + +   + V     L   L  
Sbjct  395  YDARLANYLLSTVEDN-ELSTIAR--IFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLAR  451

Query  464  KIK------EQDMEEL-------LY-KVEQPLTETLSAMETEGFKVDKDILLQLEKKFKG  509
            K+K       Q ++ L       LY ++E PL++ L+ ME EG+KV++  L ++  + K 
Sbjct  452  KVKVLLDSKSQMLDKLTAHEQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKV  511

Query  510  EIESTQLEIYSMSEEEFNINSPKQLGKILFEKLDLP--VIKKTKTGYSTNAEVLDKLRDK  567
             IE+   EIY M+ +EFNINSPKQLG ILFEK++LP  + KKTKTGYST  +VL++L   
Sbjct  512  IIEALTQEIYDMAGQEFNINSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPI  571

Query  568  HPIIDKITYYRQLTKIYSTYIEGLKAAIDEDGKIHSNFNQTVTATGRLSSTEPNLQNIPI  627
             PI+ KI  YRQ+TK+ STY+ GL+  I  DGKIH+ + Q +T TGRLSS +PNLQNIPI
Sbjct  572  APIVAKILDYRQITKLQSTYVIGLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPI  631

Query  628  KYEMGREIRKVFIPNTGDSVILSADYSQIELRVLAHISDDKNMISAFNEHDDIHTKTASE  687
            + E GR IRK F P+  D+V+LS+DYSQIELRVLAHIS+D ++I+AFNE  DIHT TA  
Sbjct  632  RLEQGRLIRKAFTPSHEDAVLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMR  691

Query  688  VFKVP-IEEVTPLMRGNAKAVNFGIVYGIGDFSLSQDLNITRKEAKQYIDAYLERYPNVK  746
            VF +    +VT+  R NAKAVNFGIVYGI+DF+LS++L ITRK++K YID+Y+ERYP +K
Sbjct  692  VFGIDKAADVTANDRRNAKAVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIK  751

Query  747  LYLENIVEEAIEKGYVSTILNRRRYIKEVKSSNKIVKAAGERLAMNSPIQGSAADIIKLA  806
             Y+EN+V EA +KGYV T+++RRR + +++S N  V++ +ER A+NSPIQGSAADI+K+A
Sbjct  752  AYMENVVREAKDKGYVETLFKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIA  811

Query  807  MVNVHRKLKEDNFKSSIILQVHDELILNVHKDELEKIKALVKKEMEQVLELKVGLDVDIN  866
            M+N+++ L+ + F++ ++LQVHDE++L+V +DEL  IK LVK  ME  ++L V L VD +
Sbjct  812  MINLDKALQAGGFRAKMLLQVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDES  871

Query  867  IGNNWYEAK  875
             G++WYEAK
Sbjct  872  TGQSWYEAK  880

426) polA in NC_012563


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  576 bits (2177),  Expect = 2e-165, Method: Compositional matrix adjust.
 Identities = 402/909 (45%), Positives = 608/909 (67%), Gaps = 66/909 (7%)

Query  2    NKERLLILDSNSLLNRAFYAL----PDLMTGEGIHTNAIYGFVNMLLKMKEEINPDYIVA  57
            NK++LL++D++S+  RAF+AL      +    G+HTNAIYGF  ML  M   + P  ++ 
Sbjct  3    NKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLV  62

Query  58   AFDRKAPTFRHEEYKDYKAGRKKMPEELAQQFPIVKELLSALAINIFEIDGFEADDLIGT  117
            AFD    TFR E Y DYKAGR K P+E+ +QF+ ++E+L+AL+I  +E++ +EADD+IGT
Sbjct  63   AFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGT  122

Query  118  LSVFAEEKGI--EVYIVTGDKDALQLATDNVKVVITKKGITEKEIYDKNRMIEEFGVTPK  175
            L   AE   +  +V IV+GDKD +QL+ +N  V I+KKG++E E +    ++E  G+TP+
Sbjct  123  LDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPN  182

Query  176  EFIDVKGLMGDTSDNIPGVPGIGEKTAFKLIKEYKSIETVLENIENIKGKKLKENLHEYR  235
            +FID+K+LMGD SDNIPGV  IGEKT++KL+ E+ S+E + E+I+ +K  K+KENL + R
Sbjct  183  QFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDR  242

Query  236  EQAIFSKKLATIICNVPIDMSLEDIKSKEEYDINKVRKMFERLEFKSLMNkvsksdeeet  295
            +QA++SK LATI    PI ++L+DI  +   D+  + + ++ ++F  L + ++    +E 
Sbjct  243  DQAFLSKTLATINTASPITIGLDDIVYNGP-DVASLSQFYDEMDFVQLKKGLASQMPQEP  301

Query  296  veeevsykNIVSLEEFKDLKNNIIKYKENDLYLYFEL-------EDIVLFSKSRVKTLYA  348
            V        ++S +E  ++  ++  +  +D++ YFE        E I+ F+ ++   +YA
Sbjct  302  V-------AVISYQEVTNVSADL--FSAEDIF-YFETLRDNYHREAIIGFAWGHGEQIYA  351

Query  349  NFKDEVYRIDFEMLLNNTKEQFIEVCREMFESKEIKKITYNAKNPRTILRKLGIDFNGIK  408
            +        D+ +L   + + F    +++F+ K I   TY+ K ++ +L  LGI++ +  
Sbjct  352  S-------TDLSLL---ATDSF----KQVFQ-KPI--ATYDFKRSKVLLSHLGIELVAPS  394

Query  409  FDINLAAYLIDPVRKEYEISSLASEYLFKNINREDE---FLKI--KEVNIMPNLYKVLEE  463
            +D  LA YL+  V  + E+S++A   +F +I+ E++   + K   + V     L   L  
Sbjct  395  YDARLANYLLSTVEDN-ELSTIAR--IFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLAR  451

Query  464  KIK------DQDMEEL-------LY-KVEQPLTETLSAMETEGFKVDKDILLQLEKKFKG  509
            K+K       Q ++ L       LY ++E PL++ L+ ME EG+KV++  L ++  + K 
Sbjct  452  KVKVLLDSKSQMLDKLTAHEQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKV  511

Query  510  EIESTQLEIYSMSEEKFNINSPKQLGKILFEKLDLP--VIKKTKTGYSTNAEVLDKLRDK  567
             IE+   EIY M+ + FNINSPKQLG ILFEK++LP  + KKTKTGYST  +VL++L   
Sbjct  512  IIEALTQEIYDMAGQEFNINSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPI  571

Query  568  HPIIDKITYYRQLTKIYSTYIEGLKAAIDEDGKIHSNFNQTVTATGRLSSTEPNLQNIPI  627
             PI+ KI  YRQ+TK+ STY+ GL+  I  DGKIH+ + Q +T TGRLSS +PNLQNIPI
Sbjct  572  APIVAKILDYRQITKLQSTYVIGLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPI  631

Query  628  KYEMGREIRKVFIPNTGDSVILSADYSQIELRVLAHISDDKNMISAFNEHDDIHTKTASE  687
            + E GR IRK F P+  D+V+LS+DYSQIELRVLAHIS+D ++I+AFNE  DIHT TA  
Sbjct  632  RLEQGRLIRKAFTPSHEDAVLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMR  691

Query  688  VFKVP-IEEVTPLMRSNAKAVNFGIVYGIGDFSLSQDLNITRKEAKQYIDAYLERYPNVK  746
            VF +    +VT+  R NAKAVNFGIVYGI+DF+LS++L ITRK++K YID+Y+ERYP +K
Sbjct  692  VFGIDKAADVTANDRRNAKAVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIK  751

Query  747  LYLENIVEEAVEKGYVSTILNRRRYIKEVKSSNKIVKAAGERLAMNSPIQGSAADIIKLA  806
             Y+EN+V EA +KGYV T+++RRR + +++S N  V++ +ER A+NSPIQGSAADI+K+A
Sbjct  752  AYMENVVREAKDKGYVETLFKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIA  811

Query  807  MVNVHRKLKEDNFKSSIILQVHDELILNVHKDELERIKALVKKEMEQVLELKVGLDVDIN  866
            M+N+++ L+ + F++ ++LQVHDE++L+V +DEL  IK LVK  ME  ++L V L VD +
Sbjct  812  MINLDKALQAGGFRAKMLLQVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDES  871

Query  867  IGNNWYEAK  875
             G++WYEAK
Sbjct  872  TGQSWYEAK  880

427) polA in NC_012658


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  575 bits (2172),  Expect = 4e-165, Method: Compositional matrix adjust.
 Identities = 397/909 (44%), Positives = 611/909 (68%), Gaps = 66/909 (7%)

Query  2    NKERLLILDSNSLLNRAFYAL----PDLMTGEGIHTNAIYGFVNMLLKMKEEIKPDYIVA  57
            NK++LL++D++S+  RAF+AL      +    G+HTNAIYGF  ML  M   ++P  ++ 
Sbjct  3    NKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLV  62

Query  58   AFDRKAPTFRHEEYKDYKAGRKKMPEELAQQFPIVKDLLAALAINIFEIDGFEADDLIGT  117
            AFD    TFR E Y DYKAGR K P+E+ +QF+ ++++L+AL+I  +E++ +EADD+IGT
Sbjct  63   AFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGT  122

Query  118  LSVFAEEKGI--EVYIVTGDKDALQLATDNVKVVITKKGITEKEIYDKNRMIEEFGVTPK  175
            L   AE   +  +V IV+GDKD +QL+ +N  V I+KKG++E E +    ++E  G+TP+
Sbjct  123  LDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPN  182

Query  176  EFIDVKGLMGDTSDNIPGVPGIGEKTAFKLIKEYKSIETVLENIENIKGKKLKENLHEYR  235
            +FID+K+LMGD SDNIPGV  IGEKT++KL+ E+ S+E + E+I+ +K  K+KENL + R
Sbjct  183  QFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDR  242

Query  236  EQAIFSKKLATIICNVPIDMSLEDIKSKEEYDINKVRKMFERLEFKSLMNKVGKSDeeet  295
            +QA++SK LATI    PI ++L+DI  +   D+  + + ++ ++F  L + ++ S+  + 
Sbjct  243  DQAFLSKTLATINTASPITIGLDDIVYNGP-DVASLSQFYDEMDFVQLKKGLA-SQMPQE  300

Query  296  veeevSYKNIVSLEEFKVLKNNIIKYKENDLYLYFEL-------EDIVLFSKSRIKTLYA  348
                +SY+++ ++        ++  +  +D++ YFE        E I+ F+ ++   +YA
Sbjct  301  PVAVISYQEVTNV------SADL--FSAEDIF-YFETLRDNYHREAIIGFAWGHGEQIYA  351

Query  349  NFKDEVYRIDFEMLLKNTKEQFIEVCkeifeskeikkiTYDAKNPRTILRKLGIEFNGIK  408
            +        D+ +L   + + F +V        +    TYD K ++ +L  LGIE+ +  
Sbjct  352  S-------TDLSLL---ATDSFKQV-------FQKPIATYDFKRSKVLLSHLGIELVAPS  394

Query  409  FDINLAAYLIDPVRKEYEISSLASEYLFKNINREDE----------ILKIKEV---NMMP  455
            +D  LA YL+  V  + E+S++A   +F +I+ E++           +  K+V   ++  
Sbjct  395  YDARLANYLLSTVEDN-ELSTIAR--IFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLAR  451

Query  456  KLYKVLE------EKIKEQDMEELLYKVEQPLTETLSAMETEGFKVDKDILLQLEKKFKG  509
            K+  +L+      +K+  ++  +L  ++E PL++ L+ ME EG+KV++  L ++  + K 
Sbjct  452  KVKVLLDSKSQMLDKLTAHEQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKV  511

Query  510  EIESTQLEIYSMSEEEFNINSPKQLGKILFEKLDLP--VIKKTKTGYSTNAEVLDKLRDK  567
             IE+   EIY M+ +EFNINSPKQLG ILFEK++LP  + KKTKTGYST  +VL++L   
Sbjct  512  IIEALTQEIYDMAGQEFNINSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPI  571

Query  568  HPIIDKITYYRQLTKIYSTYIEGLKAAIDEDGKIHSNFNQTVTATGRLSSTEPNLQNIPI  627
             PI+ KI  YRQ+TK+ STY+ GL+  I  DGKIH+ + Q +T TGRLSS +PNLQNIPI
Sbjct  572  APIVAKILDYRQITKLQSTYVIGLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPI  631

Query  628  KYEMGREIRKVFIPNTGDSVILSADYSQIELRVLAHISDDKNMISAFNEHDDIHTKTASE  687
            + E GR IRK F P+  D+V+LS+DYSQIELRVLAHIS+D ++I+AFNE  DIHT TA  
Sbjct  632  RLEQGRLIRKAFTPSHEDAVLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMR  691

Query  688  VFKVP-IEEVTPLMRGNAKAVNFGIVYGIGDFSLSQDLNITRKEAKQYIDAYLERYPNVK  746
            VF +    +VT+  R NAKAVNFGIVYGI+DF+LS++L ITRK++K YID+Y+ERYP +K
Sbjct  692  VFGIDKAADVTANDRRNAKAVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIK  751

Query  747  LYLENIVEEAVEKGYVNTILNRRRYIKEVKSSNKIVKAAGERLAMNSPIQGSAADIIKLA  806
             Y+EN+V EA +KGYV+T+++RRR + +++S N  V++ +ER A+NSPIQGSAADI+K+A
Sbjct  752  AYMENVVREAKDKGYVETLFKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIA  811

Query  807  MVNVHRKLKEDNFKSSIILQVHDELILNVYKDELEKIKALVKKEMEQVLELKVGLDVDIN  866
            M+N+++ L+ + F++ ++LQVHDE++L+V +DEL  IK LVK  ME  ++L V L VD +
Sbjct  812  MINLDKALQAGGFRAKMLLQVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDES  871

Query  867  IGNNWYEAK  875
             G++WYEAK
Sbjct  872  TGQSWYEAK  880

428) polA in NC_010520


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  573 bits (2164),  Expect = 2e-164, Method: Compositional matrix adjust.
 Identities = 403/909 (45%), Positives = 604/909 (67%), Gaps = 66/909 (7%)

Query  2    NKERLLILDSNSLLNRAFYAL----PDLMTGEGIHTNAIYGFVNMLLKMKEEINPDYIVA  57
            NK++LL++D++S+  RAF+AL      +    G+HTNAIYGF  ML  M   + P  ++ 
Sbjct  3    NKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLV  62

Query  58   AFDRKAPTFRHEEYKDYKAGRKKMPEELAQQFPIVKELLSALAINIFEIDGFEADDLIGT  117
            AFD    TFR E Y DYKAGR K P+E+ +QF+ ++E+L+AL+I  +E++ +EADD+IGT
Sbjct  63   AFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGT  122

Query  118  LSVFAEEKGI--EVYIVTGDKDALQLATDNVKVVITKKGITEKEIYDKNRMIEEFGVTPK  175
            L   AE   +  +V IV+GDKD +QL+ +N  V I+KKG++E E +    ++E  G+TP+
Sbjct  123  LDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPN  182

Query  176  EFIDVKGLMGDTSDNIPGVPGIGEKTAFKLIKEYKSIETVLENIENIKGKKLKENLHEYR  235
            +FID+K+LMGD SDNIPGV  IGEKT++KL+ E+ S+E + E+I+ +K  K+KENL + R
Sbjct  183  QFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDR  242

Query  236  EQAIFSKKLATIICNVPIDMSLEDIKSKEEYDINKVRKMFERLEFKSLMNKVGKSAeeet  295
            +QA++SK LATI    PI ++L+DI  +   D+  + + ++ ++F  L + ++ S   + 
Sbjct  243  DQAFLSKTLATINTASPITIGLDDIVYNGP-DVASLSQFYDEMDFVQLKKGLA-SQMPQE  300

Query  296  veeevSYKNIVSLEEFKDLKNNIIKYKENDLYLYFEL-------EDIVLFSKSRIKTLYA  348
                +SY+++ ++    DL      +  +D++ YFE        E I+ F+ ++   +YA
Sbjct  301  PVAVISYQEVTNVSA--DL------FSAEDIF-YFETLRDNYHREAIIGFAWGHGEQIYA  351

Query  349  NFKDEVYRIDFEMLLNNTKEQFIEVCkeifeskeikkiTYDAKNPRTILRKLGIEFNGIK  408
            +        D+ +L   + + F +V        +    TYD K ++ +L  LGIE+ +  
Sbjct  352  S-------TDLSLL---ATDSFKQV-------FQKPIATYDFKRSKVLLSHLGIELVAPS  394

Query  409  FDINLAAYLIDPVRKEYEISSLASEYLFKNINREDE---FLKI--KEVNIMPNLYKVLEE  463
            +D  LA YL+  V  + E+S++A   +F +I+ E++   + K   + V     L   L  
Sbjct  395  YDARLANYLLSTV-EDNELSTIAR--IFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLAR  451

Query  464  KIK------DQDMEEL-------LY-KVEQPLTETLSAMETEGFKVDKDILLQLEKKFKG  509
            K+K       Q ++ L       LY ++E PL++ L+ ME EG+KV++  L ++  + K 
Sbjct  452  KVKVLLDSKSQMLDKLTAHEQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKV  511

Query  510  EIESTQLEIYSMSEEEFNINSPKQLGKILFEKLDLP--VIKKTKTGYSTNAEVLDKLRDK  567
             IE+   EIY M+ +EFNINSPKQLG ILFEK++LP  + KKTKTGYST  +VL++L   
Sbjct  512  IIEALTQEIYDMAGQEFNINSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPI  571

Query  568  HPIIDKITYYRQLTKIYSTYIEGLKAAIDEDGKIHSNFNQTVTATGRLSSTEPNLQNIPI  627
             PI+ KI  YRQ+TK+ STY+ GL+  I  DGKIH+ + Q +T TGRLSS +PNLQNIPI
Sbjct  572  APIVAKILDYRQITKLQSTYVIGLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPI  631

Query  628  KYEMGREIRKVFIPNTGDSVILSADYSQIELRVLAHISDDKNMISAFNEHDDIHTKTASE  687
            + E GR IRK F P+  D+V+LS+DYSQIELRVLAHIS+D ++I+AFNE  DIHT TA  
Sbjct  632  RLEQGRLIRKAFTPSHEDAVLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMR  691

Query  688  VFKVP-IEEVTPLMRSNAKAVNFGIVYGIGDFSLSQDLNITRKEAKQYIDAYLERYPNVK  746
            VF +    +VT+  R NAKAVNFGIVYGI+DF+LS++L ITRK++K YID+Y+ERYP +K
Sbjct  692  VFGIDKAADVTANDRRNAKAVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIK  751

Query  747  LYLENIVEEAVEKGYVSTILNRRRYIKEVKSSNKIVKAAGERLAMNSPIQGSAADIIKLA  806
             Y+EN+V EA +KGYV T+++RRR + +++S N  V++ +ER A+NSPIQGSAADI+K+A
Sbjct  752  AYMENVVREAKDKGYVETLFKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIA  811

Query  807  MVNVHRKLKEDNFKSSIILQVHDELILNVYKDELEKIKALVEKEMEQVLELKVGLDVDIN  866
            M+N+++ L+ + F++ ++LQVHDE++L+V +DEL  IK LV   ME  ++L V L VD +
Sbjct  812  MINLDKALQAGGFRAKMLLQVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDES  871

Query  867  IGNNWYEAK  875
             G++WYEAK
Sbjct  872  TGQSWYEAK  880

429) Desku_0593 in NC_015573


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  568 bits (2144),  Expect = 6e-163, Method: Compositional matrix adjust.
 Identities = 378/909 (42%), Positives = 599/909 (66%), Gaps = 63/909 (6%)

Query  2    QESTFLILDGNSLAHRAF----HAIPHLATSQGVATNAVYGFTNMLLKVLKELKPGLVAV  57
            + + +L++DG+S+A RAF    + I ++    G+ TNA+YGF  ML  ++K ++P  V V
Sbjct  3    NKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLV  62

Query  58   CFDKGKITFRHDHYEDYKAHRPATPDELRPQFPLIKEVLAAMNIPVLEREGYEADDLIGT  117
             FD GK TFR + Y DYKA R+ TPDE+R QF+ I+E+L+A+ I+  E E YEADD+IGT
Sbjct  63   AFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGT  122

Query  118  LVNRAEQAGIS--SIIVTGDQDTLQLVSPLTRVFLTRKGISELEEYTEGRVWERFGITPA  175
            L + AE++ ++    IV+GD+D +QL    T V +++KG++E+EE+T + + E+ G+TP 
Sbjct  123  LDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPN  182

Query  176  QFPDYKGLVGDPSDNIPGVPGIGPKTAKALLKEYGCLEELVSQVDSL-PVRFRDKILPYQ  234
            QF D K+L+GD SDNIPGV  IG KT+  LL E+G LE +  ++D++   + +++++  +
Sbjct  183  QFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDR  242

Query  235  EQALLSKRLATIEREVPLEIDVDAFRWPGPDYNRLLALFSRLEFKTLIRAIRQELGQPAR  294
            +QA+LSK LATI+   P+ I++D +   GPD   L  ++  ++F  L +++  ++ Q + 
Sbjct  243  DQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEPV  302

Query  295  VVETYRVTFRVLAD---QEEL---SRLVELCRRAGRVAIALSGSRQEGIVAAALGLKAPG  348
             V +Y+    V AD    E++     L +  +R + +++A  G  ++   ++ L+L A  
Sbjct  303  AVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFA-WGHGEQIYASTDLSLLAT-  360

Query  349  DSPEAPYLSIFYLEPGDPASNPAALDTLAGIFRDPDTEKLLHDGKSALWLLQKHGLALNN  408
                                     D++  +F+ P +     D K +  LL   G+ L  
Sbjct  361  -------------------------DSFKQVFQKPIAT---YDFKRSKVLLSHLGIELVA  392

Query  409  LAFDTMVAAYLLNPASANQ------ELADLALEHLKVVLPARGEEALAARA----DVIWR  458
             ++D+ +A YLL+    N+       ++D++LE+   V    +  A++ +     ++ ++
Sbjct  393  PSYDARLANYLLSTVEDNELSTIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARK  452

Query  459  LSELLA------EKLRLAEMERLYYEVELPLVAVLADMEMTGVAVDKQYLEEMSRELEIK  512
            +  LL       +KL   E   LY ++ELPL  VLA ME+ G+ V++  L++M+ +  + 
Sbjct  453  VKVLLDSKSQMLDKLTAHEQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVI  512

Query  513  LAAIAEQIYQLAGEQFNINSTRQLGYILFEKLELP--VIKKTKTSYSTDASVLEELAGAH  570
            + A++++IY++AG++FNINS +QLG ILFEK++LP  + KKTKT+YST   VLE LA   
Sbjct  513  IEALTQEIYDMAGQEFNINSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIA  572

Query  571  PIVPLVLEYRQLMKLKSTYVDGLAALINPETGRLHTTFHQTVTATGRLSSSDPNLQNIPI  630
            PIV+ +L+YRQ+ KL+STYV GL   I ++ G++HT + Q +T TGRLSS DPNLQNIPI
Sbjct  573  PIVAKILDYRQITKLQSTYVIGLQDYILAD-GKIHTRYVQDLTQTGRLSSVDPNLQNIPI  631

Query  631  RMEEGRKIRRVFIPRREGNLILTADYSQIELRILAHMAGDPNLLEAFRQGQDIHTRTAAE  690
            R+E+GR IR+ F P +E+ ++L++DYSQIELR+LAH++GD +L+ AF +G DIHT TA  
Sbjct  632  RLEQGRLIRKAFTPSHEDAVLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMR  691

Query  691  VFGVA-ITEVTADMRGRAKAVNFGIVYGISDFGLARDINVSRQEARQYIENYFARYAGVK  749
            VFG+   ++VTA+ R  AKAVNFGIVYGISDFGL+ ++ ++R++++ YI+ YF RY+G+K
Sbjct  692  VFGIDKAADVTANDRRNAKAVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIK  751

Query  750  AFIERTIQQAREKGYVTTLLNRRRYLPDLFSANRNVRMFGERTAINTPIQGSAADIIKLA  809
            A++E  +++A++KGYV TL++RRR LPD+ S N NVR F+ERTAIN+PIQGSAADI+K+A
Sbjct  752  AYMENVVREAKDKGYVETLFKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIA  811

Query  810  MVRIHRELKDRGLATRMILQVHDELIFDMPAGELPEVSELVRRHMENALVLDVPLVVDMK  869
            M+ +++ L+  G+ ++M+LQVHDE+++++P +EL  +  LV+  ME A+ L VPL VD  
Sbjct  812  MINLDKALQAGGFRAKMLLQVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDES  871

Query  870  LGPNWYEVK  878
             G +WYE K
Sbjct  872  TGQSWYEAK  880

430) CTC02103 in NC_004557


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  566 bits (2138),  Expect = 2e-162, Method: Compositional matrix adjust.
 Identities = 383/911 (43%), Positives = 621/911 (69%), Gaps = 66/911 (7%)

Query  7    MPKRDKLVILDGNSLMNRAFYAL----PPLTNHEGVHTNAVYGFTNMLLKIKDDIKPDYI  62
            M +++KL+++DG+S+  RAF+AL      + NH G+HTNA+YGF  ML  +   ++P  +
Sbjct  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60

Query  63   VCTFDKSAPTFRHQAYKDYKAGRKKMPEELREQFPIVKGLLSKLAieifeiegfeADDLI  122
            + +FD +  TFR + Y DYKAGR K P+E+REQF+ ++ +L+ L+I  +E+E +EADD+I
Sbjct  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120

Query  123  GTLSKFAEEKDI--EVYIVTGDKDALQLASDTTKILFTKRGITEREIYDRQKVVDEMGVT  180
            GTL K AE  ++  +V IV+GDKD +QL+ + T + ++K+G++E E +    +++ MG+T
Sbjct  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180

Query  181  PTEFIDVKGLMGDPSDNIPGVPGIGEKTALKLIKEYSSVENVLNNIENLSGKKLKENLIE  240
            P +FID+K+LMGD SDNIPGV  IGEKT+LKL+ E++S+E + ++I+ +   K+KENLI+
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  241  NSEQAIFSKKLATIMRNVPIDIDLEKIKSKEEYDIEAVREIFIKLQF----KSLIDKIPK  296
            + +QA++SK LATI    PI I+L+ I  +   D+ ++ +++  ++F    K+L  ++P+
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGP-DVASLSQFYDEMDFVQLKKGLASQMPQ  299

Query  297  GenhkeveeeeelvyeeihtieDLIKLCTEIGNKDEKIYVNFKSTDTSLYSKISLEKLYI  356
                             + + +++ ++ +++ + ++ +Y  F +   + Y + ++     
Sbjct  300  E-------------PVAVISYQEVTNVSADLFSAEDIFY--FETLRDN-YHREAI-----  338

Query  357  LFKNKCYVVNIEERIEENKDKTI---EILKTIFEKEAVRVVSHDVKVLSMALKKLDVEFT  413
                  +     E+I  + D ++   + +K +F+K    + + D K   + L  L++E+ 
Sbjct  339  ----IGFAWGHGEQIYASTDLSLLATDSFKQVFQK---PIATYDFKRSKVLLSHLGIELV  391

Query  414  KALFDLKIAAYLIDSSKSDYDLSTLIQECLSKIVKDDEE--------REIRETS-LLEKL  464
             + +D ++A YL+ +   + +LST I   ++ I  ++++        R + +   LLE L
Sbjct  392  APSYDARLANYLLSTVEDN-ELST-IARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHL  449

Query  465  CANLK----------EQIINLEMEKLYYEVELPLAFVLANMELEGFKVDGEMLENIGKKL  514
              ++K          +++   E   LY ++ELPLA VLA+ME+EG+KV+   L++++ + 
Sbjct  450  ARKVKVLLDSKSQMLDKLTAHEQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQN  509

Query  515  QREIEKVQKEIYELADEEFNVNSPKQLGKILFEKLDLP--VIKKTKTGYSTNAQVLEVLE  572
            +  IE + +EIY++A++EFN+NSPKQLG ILFEK++LP  + KKTKTGYST  +VLE L 
Sbjct  510  KVIIEALTQEIYDMAGQEFNINSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLA  569

Query  573  DKHPIISKIGYYRQLTKLYSTYVEGLKNVIDEDGRIHSSFNQTVTTTGRLSSTEPNLQNI  632
               PI++KI  YRQ+TKL STYV GL++ I  DG+IH+ + Q +T TGRLSS +PNLQNI
Sbjct  570  PIAPIVAKILDYRQITKLQSTYVIGLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNI  629

Query  633  PIKYEMGREVRKVFVPNYENSIILSADYSQIELRVLAHIADDENLINAFKHHADIHTKTA  692
            PI+ E GR +RK F P+ E++++LS+DYSQIELRVLAHI++DE+LI AF++ ADIHT TA
Sbjct  630  PIRLEQGRLIRKAFTPSHEDAVLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTA  689

Query  693  SEVFKVP-IDEVTVNMRGNAKAVNFGIVYGIGDFSLAKDLKISRKEAKGYIDTYFERYPN  751
              VF +    +VT N R NAKAVNFGIVYGI+DF+L+++L I+RK++K+YIDTYFERYP 
Sbjct  690  MRVFGIDKAADVTANDRRNAKAVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPG  749

Query  752  VKKYMDETIDKAKRDMYVTTILNRRRFIPEIGNKNKIVKALGERLAMNTPIQGSAADIIK  811
            +K YM++ +  AK   YV T+++RRR +P+I ++N  V++++ER A+N+PIQGSAADI+K
Sbjct  750  IKAYMENVVREAKDKGYVETLFKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILK  809

Query  812  MAMVKVFNVLKERDLKSKIILQVHDELILNVYKDELEEIKSIVKDSMENVLPLSVPLEVD  871
            +AM+++ + L+  ++++K++LQVHDE++L+V +DEL  IK +VKD+ME  + L+VPL VD
Sbjct  810  IAMINLDKALQAGGFRAKMLLQVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVD  869

Query  872  INEGENWYDAK  882
             + G++WY+AK
Sbjct  870  ESTGQSWYEAK  880

431) Moth_1841 in NC_007644


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  564 bits (2131),  Expect = 7e-162, Method: Compositional matrix adjust.
 Identities = 383/907 (43%), Positives = 595/907 (66%), Gaps = 62/907 (6%)

Query  4    KTARLLLVDGNSVIHRAFHAL----PPLQTREGIRTNAVYGFATMLQKAREMFKPDYIIV  59
            +  +LLL+DG+SV  RAF AL      ++ + G++TNA+YGF  ML+      +P  ++V
Sbjct  3    NKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLV  62

Query  60   AFDHSKVTFRNELYDEYKGTRPETDPELRPQFALVKRLLAAWNLASCEVEGYEADDLIGT  119
            AFD +K TFR E+Y +YK+ R+ T  E+R QF+ ++ +L+A  +A  E+E YEADD+IGT
Sbjct  63   AFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGT  122

Query  120  LSRQGAATG--LEVLILTGDRDALQLVGERVKVLLMRRGLSQVEVIDREAIKKNYGLEPE  177
            L + +  T   ++V I++GD+D +QL +E   V + ++G+++ E +    +  + GL P+
Sbjct  123  LDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPN  182

Query  178  QLIDVKALMGDASDNIPGVPGVGEKTAVQLVRQYGDLEGVLAHSGEIKGRRVAENLVTFA  237
            Q+ID+KALMGD SDNIPGV  +GEKT+++L++++G LEG+  H + +K  ++ ENL+   
Sbjct  183  QFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDR  242

Query  238  DQARLARRLATIDCQAPVTLDLAGCCNQSPDYEAVLALYKELEFHSLVKDVLRAMEQEGK  297
            DQA L++ LATI+  +P+T++L +   ++PD  ++  +Y E++F  L K++   M     
Sbjct  243  DQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQM-----  297

Query  298  KASQETTAVRGlslpdpltldsleelaelvarlvGKTDVALELILNNPS-YLEA------  350
              +QE  AV +                         T+V+ +L+  +   Y+E+      
Sbjct  298  --PQEPVAVISYQEV---------------------TNVSADLFSAEDIFYFETLRDNYH  334

Query  351  AAVAVGLAWEDGVAVLGTAGIEPAALAGTLEPLLRVNPIFHDAKRALVWFSNAGAGVADP  410
                +G+AW +G  + +++++   A  +  + + +  + + D KR+ V +S+ G  +  P
Sbjct  335  REAIIGFAWGHGEQIYASTDLSLLATDSFKQVFQKPIATY-DFKRSKVLLSHLGIELVAP  393

Query  411  GGDTMVAGYLLNPSASRHDLPELCLEHLNLALVEGDS----------PQ---Laaarraa  457
            + D+ +A YLL ++   ++L+ +     +++L E+D+          P+   L       
Sbjct  394  SYDARLANYLL-STVEDNELSTIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARK  452

Query  458  VIRLLHR--ELASKLQVAGMENLYRRVELPLTRVLGAMESYGVAVNMETLDLMGIELEGG  515
            V  LL+   ++  KL      +LY+ +ELPL+ VL+ ME  G+ VN  TL+ M+ +    
Sbjct  453  VKVLLDSKSQMLDKLTAHEQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVI  512

Query  516  LAALTEAIYELAGEEFNLNSPKQLAVILFEKLGLP--PVKRTKTGFSTDAAVLEELACRH  573
            + ALT+ IY++AG+EFN+NSPKQL+ ILFEK+ LP    K+TKTG+ST   VLE LA   
Sbjct  513  IEALTQEIYDMAGQEFNINSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIA  572

Query  574  PIAAKLVEYRQLAKLKSTYVDGLKPLVNPRTGSLHTSFNQTVTATGRLSSSEPNLQNIPV  633
            PI AK+++YRQ++KL+STYV GL+  + +  G +HT + Q +T TGRLSS +PNLQNIP+
Sbjct  573  PIVAKILDYRQITKLQSTYVIGLQDYILA-DGKIHTRYVQDLTQTGRLSSVDPNLQNIPI  631

Query  634  RLELGRRLRKAFVPHGPGRLLLAADYSQIELRILAHISGDEAMIAAFRRGEDIHARTAAE  693
            RLE GR +RKAF P   + +LL++DYSQIELR+LAHISGDE +IAAF  G DIH+ TA  
Sbjct  632  RLEQGRLIRKAFTPSHEDAVLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMR  691

Query  694  VFGVP-LGEVTPAMRRSAKAVNFGIVYGISDYGLSRDLGISRSEAHDYIERYFRRYRGVK  752
            VFG+   ++VT+  RR+AKAVNFGIVYGISD+GLS +LGI+R ++  YI+ YF RY G+K
Sbjct  692  VFGIDKAADVTANDRRNAKAVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIK  751

Query  753  AYLEEIVARARQEGYVTTLLGRRRYLPDLFSSNRNVRSFGERTAMNTPIQGTAADIIKMA  812
            AY+E++V  A++ GYV TL+ RRR LPD+ S N NVRSF+ERTA+N+PIQG+AADI+K+A
Sbjct  752  AYMENVVREAKDKGYVETLFKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIA  811

Query  813  MVKIFRLLEAQYPAARMILQVHDELIFDVPDDDLPAVAGLVKDTMEHTLELQVPLQVDLK  872
            M+++ + L+A    A+M+LQVHDE++++VP+D+L A+  LVKDTME +++L VPL VD  
Sbjct  812  MINLDKALQAGGFRAKMLLQVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDES  871

Query  873  AGPNWYD  879
            +G +WY+
Sbjct  872  TGQSWYE  878

432) polA in NC_020134


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  564 bits (2131),  Expect = 8e-162, Method: Compositional matrix adjust.
 Identities = 388/903 (43%), Positives = 613/903 (68%), Gaps = 34/903 (3%)

Query  2    NPKIILIDGNSILNRGFYALSGR-SMLTTSTGLYTNAVFAFVNILNKYIEEENPDYIAVA  60
            + K++LIDG+S+  R+F+AL  +   +   +GL TNA+++F  +L+  +    P  + VA
Sbjct  4    KNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVA  63

Query  61   FDLRAKTFRHGLYEGYKAQRKGMPDELAMQIPLAKEVLRAMNIAIIEHEGYEADDIIGSL  120
            FD    TFR  +Y +YKA R   PDE+  Q++  +E+L A+ IA  E E YEADDIIG+L
Sbjct  64   FDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTL  123

Query  121  SLKAEKEN--FDVIILTGDRDSFQLISDRVKVILPSTKAGKTETNVYDKQAIIDKYGVLP  178
               AE+ +  FDV I++GD+D +QL  +  + ++  +K G +E + +    +++K G+ P
Sbjct  124  DKMAERTEVPFDVTIVSGDKDLIQLTDE--NTVVEISKKGVAEFEEFTPAYLMEKMGLTP  181

Query  179  HQLIDVKGLMGDSSDNIPGVPGVGEKTALSLISAYGTLEGVYEHIDEIKQPKLKASLIEY  238
            +Q+ID+K+LMGD SDNIPGV  +GEKT+L L+  +G+LEG+YEHID +K +K+K +LI+ 
Sbjct  182  NQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIND  241

Query  239  KDQAFLSRKLGTIVRNLELCASLEDLKRKEINRKELLNVFRKLEFESIISKMNLASAEVT  298
            +DQAFLS+ L+TI     +  +L+D+  +  +   L + +  ++F      ++L  +  +
Sbjct  242  RDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDF------VQLKKGLAS  295

Query  299  ELPPAPEELKITHISAAEDLKKWIAYLLNQKNISVLQLIDREDSYSSRLSGLALCTGDEV  358
            ++P  P       + + +++ +  A L++  +I  ++ + R++     + G+A   G+++
Sbjct  296  QMPQEP-----VAVISYQEVTNVSADLFSAEDIFYFETL-RDNYHREAIIGFAWGHGEQI  349

Query  359  FYIETGTALPENLIATELKELWQNENIHKIGHNIKEFITWLLKHDVELNGLYFDTMIAEY  418
             Y  T+ +L   L +  +K++ Q+        ++K     L   ++EL +  +D+ +A+Y
Sbjct  350  -YASTDLSL---LATDSFKQVFQK---PIATYDFKRSKVLLSHLGIELVAPSYDARLANY  402

Query  419  LIDSIRNGYPIASLSHKYLNRSVPSLDELLGKGKGAKKYSEIPP-ERLKDYSAYNVKAIF  477
            L+ ++ +   ++++++ + + S+   D + GKG  AK+   +P  + L +  A +VK ++
Sbjct  403  LLSTVEDN-ELSTIARIFTDISLEEDDTVYGKG--AKR--AVPDKDVLLEHLARKVKVLL  457

Query  478  DIWPMQKKVLQENRQEELFNDIELPLITVLASMEYHGFKVDAAKLHEYGEVLLSRIKDLE  537
            D  +     L  + Q +L+++IELPL  VLA ME +G+KV+ A L++ +E     I  L 
Sbjct  458  DSKSQMLDKLTAHEQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALT  517

Query  538  KVIYMLAGEEFNINSTKQLGTILFEKLKLP--VVKSTKTGYSTDVEVLEELYYKHDIIPC  595
            + IY +AG+EFNINS KQLG+ILFEK++LP  + K TKTGYST V+VLE L     I++ 
Sbjct  518  QEIYDMAGQEFNINSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAK  577

Query  596  IIEYRQLTKLYTTYAEGLEKVINPVTGKIHSSFNQTVTATGRISSTEPNLQNIPVRHEMG  655
            I++YRQ+TKL +TY  GL+  I +  GKIH+ + Q +T TGR+SS +PNLQNIP+R E G
Sbjct  578  ILDYRQITKLQSTYVIGLQDYILA-DGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQG  636

Query  656  REIRKAFIPSSENAVFVDADYSQIELRVLAHITGDEALINAFVKGEDIHTATASLVFDVA  715
            R IRKAF PS E+AV++ +DYSQIELRVLAHI+GDE LI AF  G DIHT+TA  VF++ 
Sbjct  637  RLIRKAFTPSHEDAVLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGID  696

Query  716  -PEDVTPELRRKAKAVNFGIVYGISDYGLARDLGITRKEAKRYIDDYFAKYPKVKTYVDE  774
             + DVT++ RR+AKAVNFGIVYGISD+GL+ +LGITRK++K YID YF +YP +K+Y+++
Sbjct  697  KAADVTANDRRNAKAVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMEN  756

Query  775  IVRVGQEQGYVETLFHRRRYLPELASKNFHQRSFGKRVAMNTPIQGTAADIIKIAMVKVY  834
            +VR ++++GYVETLF RRR LP++ S+NF+ RSF+ R A+N+PIQG+AADI+KIAM+++ 
Sbjct  757  VVREAKDKGYVETLFKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLD  816

Query  835  KALKESGLKSRLILQVHDELVIETFEDELETVKELVKKCMEEAVELSVPLVVDVSIGKNW  894
            KAL+ +G++++++LQVHDE+V+E  +DEL ++K LVK  ME AV+L+VPL VD S G++W
Sbjct  817  KALQAGGFRAKMLLQVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSW  876

Query  895  YEA  897
            YEA
Sbjct  877  YEA  879

433) Clst_0924 in NC_020887


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  564 bits (2131),  Expect = 8e-162, Method: Compositional matrix adjust.
 Identities = 388/903 (43%), Positives = 613/903 (68%), Gaps = 34/903 (3%)

Query  2    NPKIILIDGNSILNRGFYALSGR-SMLTTSTGLYTNAVFAFVNILNKYIEEENPDYIAVA  60
            + K++LIDG+S+  R+F+AL  +   +   +GL TNA+++F  +L+  +    P  + VA
Sbjct  4    KNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVA  63

Query  61   FDLRAKTFRHGLYEGYKAQRKGMPDELAMQIPLAKEVLRAMNIAIIEHEGYEADDIIGSL  120
            FD    TFR  +Y +YKA R   PDE+  Q++  +E+L A+ IA  E E YEADDIIG+L
Sbjct  64   FDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTL  123

Query  121  SLKAEKEN--FDVIILTGDRDSFQLISDRVKVILPSTKAGKTETNVYDKQAIIDKYGVLP  178
               AE+ +  FDV I++GD+D +QL  +  + ++  +K G +E + +    +++K G+ P
Sbjct  124  DKMAERTEVPFDVTIVSGDKDLIQLTDE--NTVVEISKKGVAEFEEFTPAYLMEKMGLTP  181

Query  179  HQLIDVKGLMGDSSDNIPGVPGVGEKTALSLISAYGTLEGVYEHIDEIKQPKLKASLIEY  238
            +Q+ID+K+LMGD SDNIPGV  +GEKT+L L+  +G+LEG+YEHID +K +K+K +LI+ 
Sbjct  182  NQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIND  241

Query  239  KDQAFLSRKLGTIVRNLELCASLEDLKRKEINRKELLNVFRKLEFESIISKMNLASAEVT  298
            +DQAFLS+ L+TI     +  +L+D+  +  +   L + +  ++F      ++L  +  +
Sbjct  242  RDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDF------VQLKKGLAS  295

Query  299  ELPPAPEELKITHISAAEDLKKWIAYLLNQKNISVLQLIDREDSYSSRLSGLALCTGDEV  358
            ++P  P       + + +++ +  A L++  +I  ++ + R++     + G+A   G+++
Sbjct  296  QMPQEP-----VAVISYQEVTNVSADLFSAEDIFYFETL-RDNYHREAIIGFAWGHGEQI  349

Query  359  FYIETGTALPENLIATELKELWQNENIHKIGHNIKEFITWLLKHDVELNGLYFDTMIAEY  418
             Y  T+ +L   L +  +K++ Q+        ++K     L   ++EL +  +D+ +A+Y
Sbjct  350  -YASTDLSL---LATDSFKQVFQK---PIATYDFKRSKVLLSHLGIELVAPSYDARLANY  402

Query  419  LIDSIRNGYPIASLSHKYLNRSVPSLDELLGKGKGAKKYSEIPP-ERLKDYSAYNVKAIF  477
            L+ ++ +   ++++++ + + S+   D + GKG  AK+   +P  + L +  A +VK ++
Sbjct  403  LLSTVEDN-ELSTIARIFTDISLEEDDTVYGKG--AKR--AVPDKDVLLEHLARKVKVLL  457

Query  478  DIWPMQKKVLQENRQEELFNDIELPLITVLASMEYHGFKVDAAKLHEYGEVLLSRIKDLE  537
            D  +     L  + Q +L+++IELPL  VLA ME +G+KV+ A L++ +E     I  L 
Sbjct  458  DSKSQMLDKLTAHEQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALT  517

Query  538  KVIYMLAGEEFNINSTKQLGTILFEKLKLP--VVKSTKTGYSTDVEVLEELYYKHDIIPC  595
            + IY +AG+EFNINS KQLG+ILFEK++LP  + K TKTGYST V+VLE L     I++ 
Sbjct  518  QEIYDMAGQEFNINSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAK  577

Query  596  IIEYRQLTKLYTTYAEGLEKVINPVTGKIHSSFNQTVTATGRISSTEPNLQNIPVRHEMG  655
            I++YRQ+TKL +TY  GL+  I +  GKIH+ + Q +T TGR+SS +PNLQNIP+R E G
Sbjct  578  ILDYRQITKLQSTYVIGLQDYILA-DGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQG  636

Query  656  REIRKAFIPSSENAVFVDADYSQIELRVLAHITGDEALINAFVKGEDIHTATASLVFDVA  715
            R IRKAF PS E+AV++ +DYSQIELRVLAHI+GDE LI AF  G DIHT+TA  VF++ 
Sbjct  637  RLIRKAFTPSHEDAVLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGID  696

Query  716  -PEDVTPELRRKAKAVNFGIVYGISDYGLARDLGITRKEAKRYIDDYFAKYPKVKTYVDE  774
             + DVT++ RR+AKAVNFGIVYGISD+GL+ +LGITRK++K YID YF +YP +K+Y+++
Sbjct  697  KAADVTANDRRNAKAVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMEN  756

Query  775  IVRVGQEQGYVETLFHRRRYLPELASKNFHQRSFGKRVAMNTPIQGTAADIIKIAMVKVY  834
            +VR ++++GYVETLF RRR LP++ S+NF+ RSF+ R A+N+PIQG+AADI+KIAM+++ 
Sbjct  757  VVREAKDKGYVETLFKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLD  816

Query  835  KALKESGLKSRLILQVHDELVIETFEDELETVKELVKKCMEEAVELSVPLVVDVSIGKNW  894
            KAL+ +G++++++LQVHDE+V+E  +DEL ++K LVK  ME AV+L+VPL VD S G++W
Sbjct  817  KALQAGGFRAKMLLQVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSW  876

Query  895  YEA  897
            YEA
Sbjct  877  YEA  879

434) FMG_0343 in NC_010376


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  563 bits (2124),  Expect = 2e-161, Method: Compositional matrix adjust.
 Identities = 373/894 (42%), Positives = 607/894 (68%), Gaps = 39/894 (4%)

Query  3    KKALIIDGSSLLFRGFYA----IRDLTTKDGIHTNGVFGFMNMYYSVMGKINPDLVVVCF  58
            +K L+IDGSS+ FR+F+A    I  +    G+HTN+++GF  M   +M ++ P  V+V F
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  59   DRKEPTFRHEKYSEYKGNRQETPEELIGQFDMLKELLKAMGVSYIDLKGYEADDIAGTLA  118
            D    TFR E Y++YK+ R  TP+E+  QF  ++E+L A+G++Y +L  YEADDI GTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  119  KQASSKD--YDVYLLTGDKDYLQLIDDNTKVVLTKRGITETKIYDVDVLKEEYGITPKQM  176
            K A   +  +DV +++GDKD +QL D+NT V ++K+G++E   +    L E  G+TP+Q 
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  177  IDLKGLMGDKSDNIPGIDGVGEKTALKYIQKYGSIEGLYEHVDEISGKKTKQKVIDGEDI  236
            IDLK+LMGDKSDNIPG+  +GEKT+LK ++ +GS+EG+YEH+D +   K K+++I++ D 
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRDQ  244

Query  237  AYLSRELGTINTDVPEDLMGFGIEDCTIKEADNDHLIEVLTKLEFNSFIKKLPNEESNEK  296
            A+LS+ L+TINT  P   + +G++D   + +D   L +    ++F  + K L+++ ++E 
Sbjct  245  AFLSKTLATINTASP---ITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEP  301

Query  297  ---FEYENLDEKVDEIKAYIKENKKFTFALFNDDYYVDNEPVI-FA-IYTDKVYITRNVE  351
               + Y+++ +   ++   +  +  F F  + D+Y  + E++I FA    +++Y + ++ 
Sbjct  302  VAVISYQEVTNVSADL---FSAEDIFYFETLRDNY--HREAIIGFAWGHGEQIYASTDLS  356

Query  352  LV--ESFKEEFESKDINKLSFDIKPCIYHLMRYGID-ISYNYDDVVIIEYLLDPSKTSYS  408
            L+  +SFK+ F+ K I   ++D+K     L + GI+ ++ +YD   + +YLL       +
Sbjct  357  LLATDSFKQVFQ-KPIA--TYDFKRSKVLLSHLGIELVAPSYDAR-LANYLLS------T  406

Query  409  MERSDPKVIGYDFKPL---EDITGKGKSKKTILESDEKEIDNYVVKYMMFTNKLYEKISE  465
            +E ++   I+  F  +   ED T  GK+ K  +   +  +++   K  ++ +   + +  
Sbjct  407  VEDNELSTIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDK  466

Query  466  IEEEDMMHLYRDVEIPLIKVLCDMEFTGVCVKKETLVEMGELFEDEIKSIEKSVEELIGK  525
            +  ++ ++LY+++E+PL +VL  ME+ G+ V++ TL +M+E     I ++ + + ++ G+
Sbjct  467  LTAHEQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQ  526

Query  526  KININSSKQLAEVLFEDLELPV--IKKNKTGPSTDQEVLEALSGRHEIIDYILRYRTITK  583
             +NINS+KQL+ +LFE ++LP+   KK KTG ST  +VLE L+    I+  IL YR ITK
Sbjct  527  EFNINSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITK  586

Query  584  LKTTYIDGMVDLIKKDGKIHTTFQQTIAQTGRISSTNPNLQNIPIRTEEGRLIRKAFVPS  643
            L++TY+ G+ D I  DGKIHT + Q ++QTGR+SS +PNLQNIPIR E+GRLIRKAF PS
Sbjct  587  LQSTYVIGLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPS  646

Query  644  -EGNMLLDADYSQIELRVLADLANDEVMLDAFKHGADIHRKTASEVFKVD-FDKVTSLQR  701
             E+ +LL +DYSQIELRVLA+++ DE ++ AF++GADIH  TA  VF +D    VT+ +R
Sbjct  647  HEDAVLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDR  706

Query  702  SNAKAVNFGIVYGIGDYSLSKDLHITRKEAKEYIENYLDTYKGIKQYMEDIVAIGKEKGY  761
             NAKAVNFGIVYGI+D++LS++L ITRK++K YI+ Y++ Y GIK YME++V  +K+KGY
Sbjct  707  RNAKAVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGY  766

Query  762  VETIMNRRRYIPELKSKNYNVRSFGERVALNTPIQGSAADIIKVAMVKFYNRLNEEKLKA  821
            VET+ +RRR +P+++S+N+NVRSF+ER A+N+PIQGSAADI+K+AM+++ + L+   ++A
Sbjct  767  VETLFKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRA  826

Query  822  KLILQVHDELIVDCPKDEREKVLEIMKDVMTHAVDLKVDMKIDVNSADNWYDAK  875
            K++LQVHDE++++ P+DE   +  ++KD M  AVDL V + +D +++++WY+AK
Sbjct  827  KMLLQVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

435) Clocl_2645 in NC_016627


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  562 bits (2122),  Expect = 4e-161, Method: Compositional matrix adjust.
 Identities = 386/905 (43%), Positives = 608/905 (68%), Gaps = 37/905 (4%)

Query  2    NKKKLMVIDGNSILNRAFYGL-QGPNLLATSDGLYTNAVYGFINIMNKYIEEENPQYICV  60
            NK+KL++IDG+S+  RAF++L +  + +    GL TNA+YGF  +++  +    P  + V
Sbjct  3    NKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLV  62

Query  61   AFDLKAPTFRHKQFDGYKANRKGMPDELRVQVPVIKEVLDAMRIKRLEMEGYEADDILGS  120
            AFD    TFR   + +YKA R   PDE+R Q + I+E+L A+ I   E+E YEADDI+G+
Sbjct  63   AFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGT  122

Query  121  ISLCAQQKGM--EVIIITGDRDALQLADKDIRIKIPKTKGGKTETEEYNLETIHGKYKIE  178
            +   A++  +  +V I++GD+D +QL+D +  + I+K   G +E EE+    +  K  + 
Sbjct  123  LDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKK--GVAEFEEFTPAYLMEKMGLT  180

Query  179  PVQFIDVKALMGDTSDNIPGVPGIGEKTALDLIQNYGTIENLYENVDNITKKALKEKLIT  238
            P QFID+KALMGD SDNIPGV  IGEKT+L L++++G++E +YE++D +    +KE+LI 
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  239  YKEQAFMSKELARIERNMPFLCNIDELARVEFDKPRLYELFKRLEFKSFIEKFGLKDSQN  298
             ++QAF+SK LA I+   P+   +D++     D + L +++  ++F  +  K GL     
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQL--KKGLASQMP  298

Query  299  QESFKVNIKRIKDKQGILELKNEIFEEKEMSFYYLIDKVDKFTNKLSGISISAKEGNSYY  358
            QE+  V        Q + ++  ++F   ++ FY+   + D++ ++ + I+++  +G+  Y
Sbjct  299  QEPVAVI-----SYQEVTNVSADLFSAEDI-FYFETLR-DNY-HREAIIGFAWGHGEQIY  350

Query  359  LAFNEDYNEKEFL--EEFKSIFEDSDIKKYGHDLKNFIVYLKNRGIELNGIAFDTMIGAY  416
             +      +  +L  + FK +F+ + I  Y  D+K   V L + GIEL + ++D+ ++ Y
Sbjct  351  AS-----TDLSLLATDSFKQVFQKP-IATY--DFKRSKVLLSHLGIELVAPSYDARLANY  402

Query  417  IINPSRDTYTISELANDYLGLSVKSVEEMAGKG--RNFMPFDAMDEEELKNVAGLYPEVI  474
            +++   D   +S +A  + ++S+   + + GKG  R     D + E+  ++V      V+
Sbjct  403  LLSTVEDN-ELSTIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKV-----KVL  456

Query  475  FKCKNKIEEKLGENDQIKLYYEIELPLVEVLADMEYYGFKVNVNELMSISRQLDEKIQEL  534
            +  K+++ +KL  ++Q+ LY +IELPL +VLA ME  G+KVN   L  ++ Q    I+ L
Sbjct  457  LDSKSQMLDKLTAHEQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEAL  516

Query  535  TVKIYELAGEEFNINSTKQLGVILFEKLELP--VIKKTKTGYSTDAEVLEELADKHEIIP  592
            T  IY++AG+EFNINS KQLG ILFEK++LP  + KKTKTGYST  +VLE LA    I++
Sbjct  517  TQEIYDMAGQEFNINSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVA  576

Query  593  KILEYRQLIKLKSTYIDGLMSVINPVTGKIHSSFNQTVTVTGRISSTEPNLQNIPIKLEM  652
            KIL+YRQ+ KL+STY+ GL   I +  GKIH+ + Q +T TGR+SS +PNLQNIPI+LE 
Sbjct  577  KILDYRQITKLQSTYVIGLQDYILA-DGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQ  635

Query  653  GRNIRKAFVSSDENYRLVDADYSQIELRVLAHITGDVNMIEAFNKNEDIHASTASKVFGV  712
            GR IRKAF +S+E+  L+ +DYSQIELRVLAHI+GD ++I AFN   DIH+STA +VFG+
Sbjct  636  GRLIRKAFTPSHEDAVLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGI  695

Query  713  P-INEVTPLLRSKAKAVNFGIVYGIGDFSLSKDLGITRKEARAYIDGYLEKYANVKKYMH  771
                +VT+  R +AKAVNFGIVYGI+DF+LS++LGITRK++++YID Y+E+Y+ +K YM+
Sbjct  696  DKAADVTANDRRNAKAVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYME  755

Query  772  DIVVQGKEFGFVTTLFGRRRYLPELKSSNFNIRSFGERIAMNTPIQGSAADIIKIAMVKV  831
            ++V ++K+ G+V TLF RRR LP+++S NFN+RSF+ER A+N+PIQGSAADI+KIAM+++
Sbjct  756  NVVREAKDKGYVETLFKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINL  815

Query  832  YKELKARKLKSRLILQVHDELIIEAHVSEVEEVTTILKESMENAVKLSVPLSVEVKSGSN  891
             K L+A  ++++++LQVHDE+++E    E+  +  ++K++ME AV L+VPL V+  +G +
Sbjct  816  DKALQAGGFRAKMLLQVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQS  875

Query  892  WYETK  896
            WYE+K
Sbjct  876  WYEAK  880

436) Toce_1653 in NC_014377


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  560 bits (2115),  Expect = 1e-160, Method: Compositional matrix adjust.
 Identities = 376/892 (43%), Positives = 590/892 (67%), Gaps = 53/892 (5%)

Query  2    KKIMLIDGNSLIHRAFHAL----PPLMTSKGVHTNAVYGFMNMLMRILKEQRPDYIAVAF  57
            +K++LIDG+S+  RAF AL      +    G+HTNA+YGF  ML +++K  RP  + VAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  58   DKKSPTFRHQEFIEYKANRVRTPEELVGQFDVLKQILKAMNIRYIEIDGYEADDILGSLS  117
            D    TFR + + +YKA R +TP+E+  QF  ++++L A+ I Y E++ YEADDI+G+L 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  118  KKAEEAGI-FTL-IVTGDKDTLQLVSPMVHVMLTRKGISEMEIYDPDKMAERFGIPPQAI  175
            K AE + + F + IV+GDKD +QL      V +++KG++E E + P  + E+ G+ P+ +
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  176  PDMKGLMGDSSDNIPGIPGVGEKTALKLLQEYGSLENILENAEKLK-GKLRENILKYGEQ  234
             D+K+LMGD SDNIPG+  +GEKT+LKLL+E+GSLE I E+ + +K +K++EN+++  +Q
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRDQ  244

Query  235  ARVSKRLATIVRDVELDVDLEEIALTEPDYAELLKIFRELEFYTLINKLPRPQEKEEHPE  294
            A +SK LATI     + ++L++I    PD A L +++ E++F  L + L+    +E    
Sbjct  245  AFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQE----  300

Query  295  KLSCTVIDYSGFGRMMERV-RAAGVLAVE-LKTD-GRNPMDAHLIGIGFSPSRGEGFYVP  351
              + +VI Y     +   +  A +++  E L+ +  R+++      IGF+ ++GE +Y +
Sbjct  301  --PVAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAI------IGFAWGHGEQIYAS  352

Query  352  AEVLEKSPEVKSDLKAVLADPGITKIIHDGKYARTVLAKIGMDFVY-NFDTMLAAYLLDP  410
            +++   S      +K V+  P  T    D K ++ +L+ +G+++V  ++D+ LA YLL  
Sbjct  353  TDL---SLLATDSFKQVFQKPIAT---YDFKRSKVLLSHLGIELVAPSYDARLANYLLST  406

Query  411  SKPRYDLESV--VFDNLGVELKGT-----------------EDPGRRVAYLIPLKEIMSE  451
                 +L ++  +F ++++E  +T                 E+ +R+V  L+  K  M +
Sbjct  407  VEDN-ELSTIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLD  465

Query  452  KLKSCAMEELFFGVEMPLSFVLSDMEMTGIKVDPEKLESLSREFGEKLEELTGEIYRLAG  511
            KL +    +L+  +E+PL+ VL+ ME+ GIKV+   L+ ++ +    +E LT EIY +AG
Sbjct  466  KLTAHEQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAG  525

Query  512  VEFNINSPKQLGEVLFEKLNLP--VIKKKKSGYSTDAEVLEKLKNAHPVVEKILEYRFLM  569
             EFNINSPKQLG +LFEK++LP  + KK K+GYST  +VLE+L    P+V KIL+YR + 
Sbjct  526  QEFNINSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQIT  585

Query  570  KMKSTYADGLLALVDKSTYRIHSNFNQTITATGRISSTEPNLQNIPVKTDIGRKIRGVFV  629
            K++STY  GL   +     +IH+ + Q +T TGR+SS +PNLQNIP++ + GR IR  F 
Sbjct  586  KLQSTYVIGLQDYILADG-KIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFT  644

Query  630  AESPEHVLLSGDYSQIELRVLAHLSGDEGLIEAFIKGEDIHTRTASEVFGVP-PEQVTPL  688
            +   + VLLS+DYSQIELRVLAH+SGDE LI AF  G DIHT TA  VFG+  + +VT+ 
Sbjct  645  PSHEDAVLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTAN  704

Query  689  LRDRAKAVNFGIIYGISDYGLAQNLGISTAEAREYIENYLNRYPKVRDYIRETIRNARMS  748
             R  AKAVNFGI+YGISD+GL++NLGI+  +++ YI+ Y++RYP ++ Y+ + +R+A+  
Sbjct  705  DRRNAKAVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDK  764

Query  749  GYVTTILNRRRYIPEINSRNYNLRSFAERVAMNTPIQGSAADIIKVAMVKITNHFREYGL  808
            GYV T+++RRR +P+INSRN+N+RSFAER A+N+PIQGSAADI+K+AM+++ + ++  G+
Sbjct  765  GYVETLFKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGF  824

Query  809  KAKMLIQVHDELIFDVPKSELEVVKNIVKDDMENAIPLKVPLVVDFKEGYTW  860
            +AKML+QVHDE++++VP+ EL  +K++VKD ME A+ L VPL VD   G +W
Sbjct  825  RAKMLLQVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSW  876

437) PolA in NC_003869


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  559 bits (2112),  Expect = 2e-160, Method: Compositional matrix adjust.
 Identities = 364/890 (41%), Positives = 594/890 (67%), Gaps = 34/890 (3%)

Query  2    AKFLLIDGSSLMYRAYYAL----PMLTTSEGLHTNALYGFTMMLIKLLEEEKPDYVAIAF  57
             K+LLIDGSS+ +RA++AL      +    GLHTNA+YGF +ML  ++   +P  V +AF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  58   DKKAPTFRHKEFKEYKATRQAMPEELSEQVELLKEVIDGFNIKTLELEGYEADDIIGTVS  117
            D    TFR   + +YKA R   P+E+ EQ   ++E++ ++ I   ELE YEADDIIGT+ 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  118  KMAEEKGM--EVVIVTGDRDALQLISPRVKVKISKKGITQMEEFDEKAVLERYEITPQQF  175
            KMAE   +  +V IV+GD+D +QL      V ISKKG+++ EEF    ++E+  +TP+QF
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  176  VDLKGLMGDKSDNIPGIPNIGEKTAIKLLKEFGSVENLLENISKL-SGKIKETIEANREL  234
            +DLK+LMGDKSDNIPG+ +IGEKT++KLL EFGS+E + E+I  + ++K+KE +  +R+ 
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRDQ  244

Query  235  AVMSKRLATINRNIPLEIDFEEYRLKEFNYKKLWDLFNKLEFYSLLDSIKKE-GEEVIPT  293
            A +SK LATIN   P+ I++++   +  +   L ++++ ++F  L  ++  +  +E ++ 
Sbjct  245  AFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEPVAV  304

Query  294  VSIRKWKKVDIREVPRLLESAKNVAFYPLIYEGDVKKIAFSF---DGTTLYSDVE----R  346
            +S +     ++ +V+  L SA ++ ++  + +   +   ++F   +G  +Y+  +     
Sbjct  305  ISYQ-----EVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLA  359

Query  347  LEDLRKIFEREDAEFVSHEIKDFLVKLSYKGIE-CKSKYLDTAIMAYLLNPSESNYDLER  405
             + ++++F++  A +     K +L  L   GIE   + Y D+ +  YLL+  E N +L  
Sbjct  360  TDSFKQVFQKPIATYDFKRSKVLLSHL---GIELVAPSY-DARLANYLLSTVEDN-ELST  414

Query  406  VLKRYLKVDILSHEEVFGKGKDRRRYEEVSE-EVMAEYICGRCSHLFELKDKLMAFIEEM  464
            + + +  + +  ++ V+GKG  R     V++ +V+ E +  +   L++ K +++  +   
Sbjct  415  IARIFTDISLEEDDTVYGKGAKR----AVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAH  470

Query  465  DMKKLLLEIEMPLVEVLKSMEVDGFTLDRNVLKELSEKIDERISEILDKIYKEAGYQFNV  524
            +   L  +IE+PL +VL  ME++G+ ++R  L++++E+    I  + + IY  AG +FN+
Sbjct  471  EQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNI  530

Query  525  NSPKQLGEFLFEKLNLP--VIKKTKTGYSTDSEVLEQLTAYNDIVSEIIEYRQLTKLKST  582
            NSPKQLG +LFEK++LP  + KKTKTGYST  +VLE+L++   IV+ I++YRQ+TKL+ST
Sbjct  531  NSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQST  590

Query  583  YIEGFLPLMDENDRVHSNFKQMVAATGRISSTEPNLQNIPVREEFGRQIRRAFIPRTKDG  642
            Y+ G+   +  ++++H+ + Q ++ TGR+SS +PNLQNIP+R E GR IR+AF P   D+
Sbjct  591  YVIGLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDA  650

Query  643  YIVSADYSQIELRVLAHLSEDEKLIEAFMNNEDIHLRTASEVFKVP-PQNVTPEMRRAAK  701
             ++S+DYSQIELRVLAH+S DE LI AF +  DIH  TA  VF +  + +VT++ RR AK
Sbjct  651  VLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAK  710

Query  702  VVNFGIIYGISDYGLAKDLKISRKEAKEYIDNYFEKYKGVKEYIEKVIRFAKENGYVTTI  761
             VNFGI+YGISD+GL+++L I+RK++K YID YFE+Y G+K Y+E+V+R AK++GYV T+
Sbjct  711  AVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETL  770

Query  762  MNRRRYIPEINSRNFTQRSQAERLAMNTPIQGSAADIIKMAMVKVYQEFKRLNLKSRLIL  821
             +RRR +P+INSRNF  RS AER A+N+PIQGSAADI+K+AM+++ + ++   ++++++L
Sbjct  771  FKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLL  830

Query  822  QVHDELVVDTYKDELELVKEILKENMENVIKLKVPLVVEIGVGPNWFLAK  871
            QVHDE+V++  +DEL  +K ++K+ ME  + L VPL V+ + G +W+ AK
Sbjct  831  QVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

438) Thexy_1599 in NC_015555


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  558 bits (2108),  Expect = 4e-160, Method: Compositional matrix adjust.
 Identities = 377/890 (43%), Positives = 590/890 (67%), Gaps = 38/890 (4%)

Query  2    SKFLIIDGNSLMYRAYFAL----PDLMNSEGMHTNAIYGFSMMllklleeekPDYIAIAF  57
            +K+L+IDG+S+ +RA+FAL      + N  G+HTNAIYGF +ML  ++   +P  + +AF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  58   DKKASTFRHKEYSAYKGTRQSMPEELIEQVDILKDVINAFNIKTIEIEGFEADDIIGTVS  117
            D   +TFR   Y+ YK+ R   P+E+ EQ   +++++ A+ I   E+E +EADDIIGT+ 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  118  KIA--SESGMDVLIVTGDRDALQLVSANVKVKICKKGITQMDEYDEKAVFEKYEVTPLQF  175
            K+A  +E   DV IV+GD+D +QL   N  V I KKG+++ +E+    + EK  +TP QF
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  176  IDLKGLMGDKSDNIPGVPNIGEKTAIKLVKEFGSIENLLMNTDKLK-GKIKENVENNAEL  234
            IDLK+LMGDKSDNIPGV +IGEKT++KL+ EFGS+E +  + D +K +K+KEN+ N+ + 
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRDQ  244

Query  235  AVLSKRLATIERNVPIDIDLNEYAVKNYDVNKLTELFEKLEFSSLISDLKDDSRDTKDIK  294
            A LSK LATI+   PI I+L++   +  DV  L+++++ ++F  L  +L  +  +     
Sbjct  245  AFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQE----  300

Query  295  EWPVRDFTY--VKNVLGK-FDVLSLYPF-----IYDGKIKAVSFACGDGSFFVEIDDYDN  346
              PV  ++Y  V NV +  F    ++ F      Y+ +   ++FA G+G    +I    +
Sbjct  301  --PVAVISYQEVTNVSADLFSAEDIFYFETLRDNYH-REAIIGFAWGHGE---QIYASTD  354

Query  347  FKLLNNDKL------TLIGHDLKDFLVNISYCGIELNCKILDTAIMTYLLNPSESNYDIS  400
            + LL  D +       +   D+K   V +S  GIEL     D+ +  YLL+  E N ++S
Sbjct  355  LSLLATDSFKQVFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDN-ELS  413

Query  401  RVLKKYLKEDLQNIDDIVGKGRNKKSYDDIDKKLLVDYMCSAASNLSKLKDKLMSFIKEM  460
             + + +    L++ D + GKG ++      DK +L++ +      L   K +++  +   
Sbjct  414  TIARIFTDISLEEDDTVYGKGAKRAV---PDKDVLLEHLARKVKVLLDSKSQMLDKLTAH  470

Query  461  EMEDLLKNVEIPLIEVLKSMEVYGFTLDKDVLRSISKEIDEKTDKIVKDIYDAAGYEFNI  520
            E  DL +N+E+PL +VL  ME+ G+ +++  L+ ++ +     + + ++IYD AG EFNI
Sbjct  471  EQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNI  530

Query  521  NSTKQLSEFLFDKLNLP--AIKKTKTGYSTDMEVLAELIPYNDIVGEIIEYRQLMKLKST  578
            NS KQL+ +LF+K++LP    KKTKTGYST ++VL  L P   IV+ I++YRQ+ KL+ST
Sbjct  531  NSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQST  590

Query  579  YIDGFIPIMDENNRVHSTFKQTVAATGRISSTEPNLQNIPVREEFGRRIRKAFVSSYEDG  638
            Y+ G+   +  + ++H+ + Q ++ TGR+SS +PNLQNIP+R E GR IRKAF +S ED+
Sbjct  591  YVIGLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDA  650

Query  639  LIISADYSQIELRVLAHLSEDEKLIESFLNNEDIHLRTASEVFKVSKE-EVTSEMRRRAK  697
            +++S+DYSQIELRVLAH+S DE LI +F +  DIH  TA  VF + K  +VT++ RR AK
Sbjct  651  VLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAK  710

Query  698  AVNFGIVYGISDYGLSKDLKISRKEAKEYIDNYFDRYKGVKNYIDSIVKFAKENGYVTTI  757
            AVNFGIVYGISD+GLS++L I+RK++K YID YF+RY G+K Y++++V+ AK++GYV T+
Sbjct  711  AVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETL  770

Query  758  LNRRRYIPEINSKNFNQRSFGERMAMNTPIQGSAADIIKMSMVKVYNELKERGLKSRLIL  817
            ++RRR +P+INS+NFN RSF+ER A+N+PIQGSAADI+K++M+++ + L+  G++++++L
Sbjct  771  FKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLL  830

Query  818  QVHDELIIDTHPDEVEIVKELLKSIMENIIKLKVPLVVDIGQGKNWYDAK  867
            QVHDE++++   DE+  +K L+K  ME  + L VPL VD + G++WY+AK
Sbjct  831  QVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

439) NT01CX_1677 in NC_008593


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  558 bits (2106),  Expect = 7e-160, Method: Compositional matrix adjust.
 Identities = 392/908 (44%), Positives = 604/908 (67%), Gaps = 61/908 (6%)

Query  2    NKERLLILDGHSLMYRAFFAL----PPLTNKEGIHTNAIYGFIKMLLKMKEEIKPDYIVT  57
            NK++LL++DG S+ +RAFFAL      + N  G+HTNAIYGF  ML  M   ++P  ++ 
Sbjct  3    NKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLV  62

Query  58   TFDKKAPTFRHKEYEEYKAGRAKMPDELNEQFPIVKDILNKLAINIFEIEGFEADDLIGT  117
            +FD    TFR   Y +YKAGRAK PDE+ EQF+ ++++L  L+I  +E+E +EADD+IGT
Sbjct  63   AFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGT  122

Query  118  LSKFAEEKGI--EVYIVTGDRDALQLATDNVRVVINKKGMSEKEIYDKNKMIEEYGVTPT  175
            L K AE   +  +V IV+GD+D +QL+ +N  V I+KKG++E E +    ++E  G+TP 
Sbjct  123  LDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPN  182

Query  176  EFIDVKGLMGDKSDNIPGVPGIGNKTALKLIKEYGSIENVLENVENISGKKMKQNLIDYR  235
            +FID+K+LMGDKSDNIPGV  IG+KT+LKL+ E+GS+E + E+++ +   KMK+NLI+ R
Sbjct  183  QFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDR  242

Query  236  EQAILSKKLATICKDVPIEINLDEIKSKEDYDIQGVRLLFQSLGFKSLLDNIGDNEGLDK  295
            +QA+LSK LATI    PI I LD+I  +   D+ ++  +++ ++F  L   ++ +  + +
Sbjct  243  DQAFLSKTLATINTASPITIGLDDIVYNGP-DVASLSQFYDEMDFVQLKKGLASQ--MPQ  299

Query  296  EDEAEVKESDINIKSTNINTIENFSKFVEGIDDSIYIQADFVDENIYSKIEFNNLYVRHK  355
            E  A +   ++   S+++ + E++  F         ++ ++  E I   I F      H 
Sbjct  300  EPVAVISYQEVTNVSADLFSAEDIFYFET-------LRDNYHREAI---IGFAW---GHG  346

Query  356  EEVFVISANEIKDKDGAKYFEILKNLFENEKIKKVCHDSKKVYVVLKKHNIAAKNIAFDT  415
            E+++  +   +   D+      +K++F++        D K+  V+L    I     ++D+
Sbjct  347  EQIYASTDLSLLATDS------FKQVFQKPI---ATYDFKRSKVLLSHLGIELVAPSYDA  397

Query  416  KIAAYLLQPSKSDYMLKDLIEEMLLLSLKDDDNI-------KINETYYIKDVY-EKLEKD  467
            ++A YLL     +  L  +      +SL +DD +        + +    KDV  E L + 
Sbjct  398  RLANYLLSTVEDN-ELSTIARIFTDISLEEDDTVYGKGAKRAVPD----KDVLLEHLARK  452

Query  468  IK-----KSNM-------EEL-LY-TVELPLIEVLASMECEGFRVDENRLTEIGEKFKKE  513
            +K     KS+M       E+L LY  +ELPL +VLA ME EG++V+   L +++E+ K  
Sbjct  453  VKVLLDSKSQMLDKLTAHEQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVI  512

Query  514  IETLEKEIHELADEEFNIKSPKQLGKILFEKLDLP--VIKKTKTGYSTNAEVLEKLKDSH  571
            IE+L +EI ++A++EFNI+SPKQLG ILFEK++LP  + KKTKTGYST  +VLE+L    
Sbjct  513  IEALTQEIYDMAGQEFNINSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIA  572

Query  572  PIIEKIIEYRQITKLDSTYVEGLKNVIDEDAKIHSSFNQTVTTTGRLSSTEPNLQNIPIK  631
            PI+ KI++YRQITKL+STYV GL++ I  D+KIH+ + Q +T TGRLSS +PNLQNIPI+
Sbjct  573  PIVAKILDYRQITKLQSTYVIGLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIR  632

Query  632  HEMGREIRKVFVPNNDESVIFSADYSQIELRILSHIADDEKLIDAFKHHKDIHTITASEV  691
             E GR IRK F P+++++V++S+DYSQIELR+L+HI++DE LI AF++  DIHT TA  V
Sbjct  633  LEQGRLIRKAFTPSHEDAVLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRV  692

Query  692  FKVP-IDEVTPLMRSNAKAVNFGIVYGIGAFSLSKDINVSRKEAKEYIDTYFSRYPNVKK  750
            F +    +VT+  R NAKAVNFGIVYGI+ F+LS+++ ++RK++K YIDTYF RYP +K 
Sbjct  693  FGIDKAADVTANDRRNAKAVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKA  752

Query  751  YIDEIISKAEVDGFVTTILNRKRYIPEIQSRNKIVRGFGERLAMNTPIQGSAADIIKLAM  810
            Y+++++  A   G+V T+++R+R +P+I+SRN  VR+F+ER A+N+PIQGSAADI+K+AM
Sbjct  753  YMENVVREAKDKGYVETLFKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAM  812

Query  811  VEVYNELKNRNLKSTLILQVHDELILNVYkdeleevkemvvdkmenvmkLLVPLEADVNV  870
            +++ + L+   +++ ++LQVHDE++L+V +DEL  +K +V D ME  + L VPL  D + 
Sbjct  813  INLDKALQAGGFRAKMLLQVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDEST  872

Query  871  GETWYEAK  878
            G++WYEAK
Sbjct  873  GQSWYEAK  880

440) Desca_1026 in NC_015565


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  557 bits (2102),  Expect = 1e-159, Method: Compositional matrix adjust.
 Identities = 395/910 (44%), Positives = 592/910 (66%), Gaps = 67/910 (7%)

Query  4    DTLLVIDGNSLVHRAFHAL----PLLSNSKGVITNAAYGFTNMLLKVLQEVEPGFVAVAF  59
            + LL+IDG+S+  RAF AL      + N  G+ TNA YGF  ML  +++ V P  V VAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  60   DKGKVTFRNEAYADYKGHRQATPDELRPQFVIVRDILKAMRIPYFELAGYEADDLIGTIT  119
            D GK TFR E YADYK+ R  TPDE+R QF  +R++L A+ I+Y+EL  YEADD+IGT+ 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  120  TRGEATG--LNVIILTGDRDALQLVSPKTKVMLTRKGITEIELFDEGLVWDKFGVTPNQI  177
              +E T   ++V I++GD+D +QL   +T V +++KG++E+E F  + + +K G+TPNQ+
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  178  VDLKALQGDASDNIPGVPGIGAKTAAALIKEHGSVEQIIKNIDNL-TPRQQKLLRGMEEQ  236
            +DLKAL GD SDNIPGV  IG KT+  L+ E GS+E I  +ID + T++ +  L    +Q
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRDQ  244

Query  237  AMLSKRLATIVTDVPMDLDLAACSWRGPDNQKLLEIFTELEFKTLIKQLLEGTKSKKSQD  296
            A LSK LATI T  P+ ++L      GPD   L +++ E++F  L K L     S+ +Q+
Sbjct  245  AFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGL----ASQMPQE  300

Query  297  GAKKTEEYVPPVNTYQVGYKVTTNQDDFDELLVNATRAGKVALYLEGTRHDGISRIFVAV  356
                      +V +YQ   +V++      +L+     ++   +Y+E  R++     +++ 
Sbjct  301  PV--------AVISYQEVTNVSA------DLF-----SAEDIFYFETLRDNYHREAIIGF  341

Query  357  P---EQDIYL---LPLQDTDPYPALTVLQALCENSEIKKYFHDAKSALWMLHHHGIELKS  410
            +    ++IY    L+L  TD++    V+Q      ++K+    +K    +L H GIEL +
Sbjct  342  AWGHGEQIYASTDLSLLATDSFKQ--VFQKPIATYDFKR----SKV---LLSHLGIELVA  392

Query  411  LAFDTMVAAYLLNPTASGYDLIDLALEHLGIVLPVNGEVSlaakadailk----------  460
             ++D+ +A YLL+      +L  +A    +I L  ++ V   +   A+            
Sbjct  393  PSYDARLANYLLSTVEDN-ELSTIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLAR  451

Query  461  -------laGELVKKLHLQEEDRLYFEVELPLVQVLADMEMAGVTVDKQGLKEMSAELHD  513
                     ++++ KL  +E+  LY ++ELPL +VLA ME+ G+ V++  L++M+ +   
Sbjct  452  KVKVLLDSKSQMLDKLTAHEQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKV  511

Query  514  MIESLAHRIHTLAGEDFNINSPKQLGHILFEKLKLP--VYKKTKTGYSTDAEVLEKLAEE  571
            +IE+L++ I  +AG++FNINSPKQLG ILFEK++LP  + KKTKTGYST  +VLE+LA  
Sbjct  512  IIEALTQEIYDMAGQEFNINSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPI  571

Query  572  HEIVALILEYRQLAKLKSTYTDGLAALVDPQTGRLHSTFHQTVTATGRLSSAEPNLQNIP  631
              IVA IL+YRQ++KL+STY  GL   + ++ G++H+ + Q +T TGRLSS +PNLQNIP
Sbjct  572  APIVAKILDYRQITKLQSTYVIGLQDYILAD-GKIHTRYVQDLTQTGRLSSVDPNLQNIP  630

Query  632  IRLESGRRIRKVFVPRQKGNLILTADYSQIELRVLAHMSQDPSFLEAFRQGQDIHTRTAA  691
            IRLE GR IRK F P + + ++L++DYSQIELRVLAH+S D  ++ AF +G DIHT TA 
Sbjct  631  IRLEQGRLIRKAFTPSHEDAVLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAM  690

Query  692  EVFGVPME-EVTPDMRSRAKAVNFGIVYGISDFGLARDLKVSRREAKSYIDNYFARCPGV  750
             VFG+    +VT++ R  AKAVNFGIVYGISDFGL+ +L ++R+++KSYID YF R PG+
Sbjct  691  RVFGIDKAADVTANDRRNAKAVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGI  750

Query  751  KDYIDRVIKEAKHTGYVTTLLNRRRYLPDLFSPNYNARSFGERAAMNTPIQGSAADIIKL  810
            K Y++ V++EAK+ GYV TL++RRR LPD+ S N+N RSF+ER+A+N+PIQGSAADI+K+
Sbjct  751  KAYMENVVREAKDKGYVETLFKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKI  810

Query  811  AMVRVARELRERNLQAKLVLQVHDELIFDVPESEVNELVDLVRDCMENAlpldvplvvdv  870
            AM+ + + L+   ++AK++LQVHDE++++VP+ E+  +  LV+D ME A+ L VPL VD 
Sbjct  811  AMINLDKALQAGGFRAKMLLQVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDE  870

Query  871  klGPNWYEVK  880
              G +WYE K
Sbjct  871  STGQSWYEAK  880

441) polA in NC_014328


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  556 bits (2099),  Expect = 2e-159, Method: Compositional matrix adjust.
 Identities = 392/905 (44%), Positives = 600/905 (67%), Gaps = 57/905 (6%)

Query  2    NDEKLLILDGHSLMHRAFYAL----PDLTNLEGVHTNAVYGFLNMLLKMKEEIKPDYVVC  57
            N +KLL++DG S+  RAF+AL      + N  G+HTNA+YGF  ML  M   ++P  V+ 
Sbjct  3    NKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLV  62

Query  58   TFDRSAPTFRHNKYSEYKAGRKKMPPELSEQFPVIKEILKMMSVSIFEIDGFEADDLMGT  117
            +FD +  TFR + Y++YKAGR K P E+ EQF+ I+E+L  ++++ +E++ +EADD++GT
Sbjct  63   AFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGT  122

Query  118  LSVFAEKNGI--QVYIVTGDRDALQLAtdkvkivitkkgitqkEIYDRNRMIEEYGVTPT  175
            L   AE+  +  +V IV+GD+D +QL+ ++  + I+KKG+++ E +    ++E  G+TP 
Sbjct  123  LDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPN  182

Query  176  QFIDVKGLMGDTSDNIPGVPGVGEKTAFKLIKQYKSIENVYENVEDISGKKLKENLKDNM  235
            QFID+K+LMGD SDNIPGV  +GEKT++KL+ ++ S+E +YE+++++   K+KENL ++ 
Sbjct  183  QFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDR  242

Query  236  EQAIFSKKLATIMTNVPVEMDLESIESKEEYDAQGLKKVFEKLEFKSLISKIHGLNEIQK  295
            +QA++SK LATI T  P+ ++L+ I  +   D  +L + ++ ++F  L     GL   Q 
Sbjct  243  DQAFLSKTLATINTASPITIGLDDIVYNGP-DVASLSQFYDEMDFVQLKK---GLAS-QM  297

Query  296  DKAQEFDVEFTEIDTLHKFSDFVNSLKNNDLVYINFKVEDEESYSRNYIDKVFISLNEKN  355
             +     + + E+  +       + +  +D+ Y+       E+   NY    +I++    
Sbjct  298  PQEPVAVISYQEVTNVS-----ADLFSAEDIFYF-------ETLRDNYHREAIIGFA---  342

Query  356  FQIHINEIYNEDKNK--AVELFKLLFENEGISKVGYDVKVPCSILYKMGIRFLKLEFDIK  413
               H ++IY        A + FK +F++   +   YD K +  +L  +GI ++   +D +
Sbjct  343  -WGHGEQIYASTDLSLLATDSFKQVFQK---PIATYDFKRSKVLLSHLGIELVAPSYDAR  398

Query  414  IAAYLIDSSRSDYELKDIIRQYTGVEISEDD------------------EKFFSKETVLF  455
            +A YL+ +   + EL  I R +T++ + EDD                  E +  K  VL+
Sbjct  399  LANYLLSTVEDN-ELSTIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLL  457

Query  456  SKVYSELTKKIEEAHMEELLY-KVEQPLIYVLASMECEGFKVDKDKLVEQEGKFKIEIDK  514
                  L K   + +++  LY ++E PL  VLA ME EG+KV++  L +   + K+ I+ 
Sbjct  458  DSKSQMLDKLTAHEQLD--LYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEA  515

Query  515  VQKEIYSLSEEEFNINSPKQLGKILFEKLDLP--VIKKTKTGYSTNAEVLEKLKDKHPIV  572
            + +EIY ++ +EFNINSPKQLG ILFEK++LP  + KKTKTGYST  +VLE+L    PIV
Sbjct  516  LTQEIYDMAGQEFNINSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIV  575

Query  573  EKIIYYRQLTKLYSTYIEGLKAVIQEDDKIHSSFNQTVTTTGRLSSTEPNLQNIPIKYEM  632
             KI+ YRQ+TKL STY+ GL+  I  D+KIH+ + Q +T TGRLSS +PNLQNIPI+ E 
Sbjct  576  AKILDYRQITKLQSTYVIGLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQ  635

Query  633  GKEIRKIFVPENEDCVILSADYSQIELRVLAHIADDENLISAFINHSDIHTKTASEVFKV  692
            G+ IRK F P +ED V+LS+DYSQIELRVLAHI++DE+LI+AF + +DIHT TA  VF +
Sbjct  636  GRLIRKAFTPSHEDAVLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGI  695

Query  693  P-IDEVTSAQRSNAKAVNFGIVYGIGDFSLAKNLKISRKEAKLYIDTYFERYPKVKLYMD  751
                +VT+ +R NAKAVNFGIVYGI+DF+L++NL I+RK++K YIDTYFERYP +K YM+
Sbjct  696  DKAADVTANDRRNAKAVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYME  755

Query  752  DIVKEAKVNSYVTTLMNRRRFIPEIKSSNKIVRSFGERLAMNTPIQGSAADIIKIAMVNV  811
            ++V+EAK ++YV TL +RRR +P+I+S N  VRSF+ER A+N+PIQGSAADI+KIAM+N+
Sbjct  756  NVVREAKDKGYVETLFKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINL  815

Query  812  YRRLEENKLKSKLILQVHDELILNVYKEEIDNvksvvkeemekvLQLKVPLEVDISVGSN  871
             + L+   +++K++LQVHDE++L+V ++E+  +K +VK+ ME  ++L VPL VD S G +
Sbjct  816  DKALQAGGFRAKMLLQVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQS  875

Query  872  WYEAK  876
            WYEAK
Sbjct  876  WYEAK  880

442) Desru_2499 in NC_015589


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  556 bits (2099),  Expect = 2e-159, Method: Compositional matrix adjust.
 Identities = 380/900 (43%), Positives = 601/900 (67%), Gaps = 55/900 (6%)

Query  6    LLVIDGNSLIHRAFHAL----PLLSNSKGVFTNAAYGFTTMLMKVLNEEQPGLVTVAFDK  61
            LL+IDG+S+  RAF AL      + N  G+ TNA YGF  ML  +++  +P  V VAFD 
Sbjct  7    LLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAFDA  66

Query  62   GKKTFRNEQYADYKGTRKATPDELRPQFLLVKDILKAMRIPYFELEGYEADDLIGTITTQ  121
            GK TFR E YADYK+ R  TPDE+R QF  ++++L A+ I+Y+ELE YEADD+IGT+   
Sbjct  67   GKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLDKM  126

Query  122  GE--SMGLNIRILTGDRDALQLVSPKTKVMLTRKGITEIELFDEGKVWDRFGIHPHQIID  179
            +E   + +++ I++GD+D +QL   +T V +++KG++E+E F  + + ++ G+ P+Q+ID
Sbjct  127  AERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQFID  186

Query  180  LKALQGDTSDNIPGVPGIGEKTAAVLIKEYGQVEEVIRNLDHL-SPRHQKLLRGHEDQAL  238
            LKAL GD SDNIPGV  IGEKT+  L+ E+G +E +  ++D + +++ +  L  + DQA+
Sbjct  187  LKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRDQAF  246

Query  239  LSKSLATIVKDVPMEIDLSQCSWRGPDYPKLLDVFNDLEFKTLIKQIIEGsrkskkskea  298
            LSK+LATI    P+ I+L +    GPD + L + +++++F  L K +             
Sbjct  247  LSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLAS-----------  295

Query  299  ksDLPPVKTYRVGYQTITDPRELPDILTKINKAGQVALSLEGSRNQGVTGMALAFD-DSE  357
              ++P      ++YQ +T+    +D+++     ++  + +E  R++      ++F  +  
Sbjct  296  --QMPQEPVAVISYQEVTNVS--ADLFS-----AEDIFYFETLRDNYHREAIIGFAWGHG  346

Query  358  VLLLPSEAMDALGLELLQSLCEDPQIKKY-FHNAKNAIWLLHRQGITLRNLAGDTMVAAY  416
              + +S  +  L+ + ++ + + P I  Y F  +K    LL + GI L   + D+ +A Y
Sbjct  347  EQIYASTDLSLLATDSFKQVFQKP-IATYDFKRSKV---LLSHLGIELVAPSYDARLANY  402

Query  417  LLNPTAANYDL-------TDIALEHLGIV--------LPVEGTMawaaaadailrlapal  461
            LL+    N +L       TDI+LE+ + V        +P  + +    A    + L +  
Sbjct  403  LLSTVEDN-ELSTIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKS  461

Query  462  H--QKLQAREEDRLYEEVELPLISVLANMEIAGITVDQQQLKEISAELQEAIEALATLIH  519
            +  +KL A+E+  LY+++ELPL +VLA+MEI GI V++  L++++ + +  IEAL+  I 
Sbjct  462  QMLDKLTAHEQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIY  521

Query  520  HLAGEEFNINSTRQLGQILFDKLKLP--VYKKTKTGYSTDAEVLEKLAEEHEIVSVLLEY  577
            ++AG+EFNINS +QLG ILF+K++LP  + KKTKTGYST  +VLE+LA    IV+ +L+Y
Sbjct  522  DMAGQEFNINSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDY  581

Query  578  RQLTKLKSTYADGLAALVDPQTKRLHSTFHQTVTATGRLSSAEPNLQNIPIRLESGRRIR  637
            RQ+TKL+STY  GL   + ++ K +H+ + Q +T TGRLSS +PNLQNIPIRLE GR IR
Sbjct  582  RQITKLQSTYVIGLQDYILADGK-IHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIR  640

Query  638  KVFVPRQRGNLILTADYSQIELRILAHVSQDASFLDAFRQGQDIHTRTASEVFGVSMD-E  696
            K F P + + ++L++DYSQIELR+LAH+S D  ++ AF +G DIHT TA  VFG+    +
Sbjct  641  KAFTPSHEDAVLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAAD  700

Query  697  VTPQLRGRAKAVNFGIVYGISDFGLARDLRVSRKEAKSYIDSYFARCPGIQNYIHRVIQE  756
            VT++ R  AKAVNFGIVYGISDFGL+ +L ++RK++KSYID+YF R PGI+ Y++ V++E
Sbjct  701  VTANDRRNAKAVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVRE  760

Query  757  AKEQGYVTTLLNRRRYLPELFSSNYNIRSFGERAAMNTPIQGTAADIIKMAMVRVHQELR  816
            AK++GYV TL++RRR LP++ S N+N+RSF+ER+A+N+PIQG+AADI+K+AM+ +++ L+
Sbjct  761  AKDKGYVETLFKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQ  820

Query  817  EQDLKAKMVLQVHDELIFDVPEQEVEKLAALVRQYMESALQMDVPLVVDIKIGPNWYDKR  876
              +++AKM+LQVHDE++++VP++E+  +  LV++ ME+A+++ VPL VD   G +WY+ +
Sbjct  821  AGGFRAKMLLQVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

443) polA in NC_018870


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  556 bits (2100),  Expect = 2e-159, Method: Compositional matrix adjust.
 Identities = 376/900 (42%), Positives = 593/900 (66%), Gaps = 63/900 (7%)

Query  1    MILDGNSLVHRAFHAL----PLLTTSGGQFTNAVYGFITMLQKIVRQEKPDYLAVAFDRS  56
            +++DG+S+  RAF AL      +   +G  TNA+YGF  ML+ ++++ +P  + VAFD +
Sbjct  8    LLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAFDAG  67

Query  57   RMTFRHRDFEDYKANRKATPDELRPQFPLVKRVLQALRIPVLELDGFEGDDLIKAVVDAA  116
            + TFR   + DYKA R  TPDE+R QF+ ++ +L AL I+  EL+ +E+DD+I ++   A
Sbjct  68   KTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLDKMA  127

Query  117  E--ERGFRVLIVTGDRDLLQLVSPQTSALITRKGISELECFTPETVRKKYGIDPAQVPDL  174
            E  E  F V IV+GD+DL+QL   +T   I++KG++E+E FTP  +  K G+ P Q  DL
Sbjct  128  ERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQFIDL  187

Query  175  KGLKGDQSDNIPGVPGIGEKTAVRLLNQFGSLEGCLANLE--KIPPRVANLLRQYSEQAV  232
            K+L GD+SDNIPGV  IGEKT+++LL++FGSLEG   +++  K +    NL+ +  +QA 
Sbjct  188  KALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIND-RDQAF  246

Query  233  ISKKLATLSKDVPIKVDFGDLKVEEPDYDALIGIYQELEFKSLLKSLReempeaaaepdd  292
            +SK LAT++   PI ++++D+  + PD  +L  +Y+E++F  L K+L  +MP+ +     
Sbjct  247  LSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEPVA---  303

Query  293  edCRIVSTMPDLIALLDELKKAGEFALCFDRGSSSPLKAPLTR---LGLAWG--EESCAV  347
                 V +  ++  +  +L  A +  + F+      L+    R   +G+AWG  E+  A 
Sbjct  304  -----VISYQEVTNVSADLFSAED-IFYFE-----TLRDNYHREAIIGFAWGHGEQIYAS  352

Query  348  VEFPSGRGQLREKMLAA--ISGLLADPECAKLCHDAKAEMIICSRNGLELKGVSGDTMLA  405
             +++         +LA+  +  ++  P  +    D K   ++ S+ G+EL + S D+ LA
Sbjct  353  TDLS---------LLATDSFKQVFQKPIAT---YDFKRSKVLLSHLGIELVAPSYDARLA  400

Query  406  AYLLNPSLSSPALEEIVLKYLG-----QVVSFDREVTRA-----------ARCARAIWKV  449
             YLL +++    L  I   + +     +   +++   RA           AR  + +   
Sbjct  401  NYLL-STVEDNELSTIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDS  459

Query  450  WPVLRTSLERDELWELFSSLELPLSGVLARMELTGVRLDVAQLEEMSREFGKHLANLVGE  509
             + +   L  +E  +L+ ++ELPL+ VLA+ME+ G++++ A L++M+ +    +  L  E
Sbjct  460  KSQMLDKLTAHEQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQE  519

Query  510  IYALAGEGFNINSPKQLGYILFEKLKLP--VIKRTKTGYSTDAEVLDKLAPYHEIAGKLL  567
            IY +AG+ FNINSPKQLG ILFEK++LP  + K+TKTGYST  +VL++LAP   I +K+L
Sbjct  520  IYDMAGQEFNINSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKIL  579

Query  568  EYRQFAKLKSTYVDGLQGLVDRETGKVHTTFNQTITATGRLSSTEPNLQNIPIKMGPGRK  627
            +YRQ++KL+STYV GLQ+ +  + GK+HT + Q +T TGRLSS +PNLQNIPI++  GR 
Sbjct  580  DYRQITKLQSTYVIGLQDYILAD-GKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRL  638

Query  628  IRRAFVPSEPGWLILAADYSQIELRVLAHMSRDERLIADFLNGEDIHTRTAATVFGVA-P  686
            IR+AF PS+ + ++L++DYSQIELRVLAH+S DE+LIA F +G DIHT TA  VFG+  +
Sbjct  639  IRKAFTPSHEDAVLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKA  698

Query  687  EEVTPDLRRRAKGINYGIVYGITEYGLARDIGVSREEAALYIANYFRQYPGVKRFIEETI  746
             +VT++ RR AK++N+GIVYGI+++GL+ ++G++R ++  YI  YF +YPG+K ++E+ +
Sbjct  699  ADVTANDRRNAKAVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVV  758

Query  747  AAARERGYVQTLLKRRRYLPDLLSSNRNVRSFGERTAINTPIQGSAADIIKLAMLRVDRE  806
              A+++GYV+TL+KRRR LPD+ S N NVRSF+ERTAIN+PIQGSAADI+K+AM+ +D+ 
Sbjct  759  REAKDKGYVETLFKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKA  818

Query  807  MRERGLRARMILQVHDELVFELPKEELGVLVPLVRSGMEKIMELAVPLRVDIEVGPNWYD  866
            ++  G+RA+M+LQVHDE+V+E+P++EL  +  LV+  ME  ++LAVPL VD   G +WY+
Sbjct  819  LQAGGFRAKMLLQVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYE  878

444) polA in NC_010163


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  555 bits (2096),  Expect = 4e-159, Method: Compositional matrix adjust.
 Identities = 374/889 (43%), Positives = 593/889 (67%), Gaps = 23/889 (2%)

Query  2    KKITLVDGNSILFRAYNATAYPGAKVLQTSTGIYTNAVFAFSGMIDKIIE-ISNSHMLIA  60
            +K+ L+DG+S+ FRA+ A  Y     ++  +G+ TNA+++F  M+D ++  +  +H+L+A
Sbjct  5    NKLLLIDGSSVAFRAFFAL-YNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVA  63

Query  61   FDTGEPTHRHKSYDDYKAGRKEMPEELGSQIPLIHELIKYLGIKEYSMAGYEADDIIGTL  120
            FD+G  T R   Y DYKAGR   P+E+  Q++ I+E++  LGI  Y +  YEADDIIGTL
Sbjct  64   FDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTL  123

Query  121  AKMAEKAG--YKVDVFSSDYDLLQLVTEHITVHMLKKGMRVVETYTPETLKETYGFSHEL  178
             KMAE++   + V + S+D DL+QL  E+  V++ KKG+   E +TP  L E  G++ + 
Sbjct  124  DKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQ  183

Query  179  FIDFKALVGDKSDNIPGVPGVGEVTAKKLIAEYGTLENILNNAEHIK-GKLGENIRTNKE  237
            FID+KAL+GDKSDNIPGV  +GE T+ KL+ E+G+LE I ++ + +K +K+ EN+  +++
Sbjct  184  FIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRD  243

Query  238  QAVFSKELSTILTDMPLPFDLEDTKVGEVDEESLINFYKRLELKQLVISYNKKNPEVAAT  297
            QA +SK L+TI T  P+ ++L+D      D  SL +FY  +++ QL     KK       
Sbjct  244  QAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQL-----KKGLASQMP  298

Query  298  TAETSEFQYKAIDSENALKSLLNQDLAIYFEFSDFNYHKAELWGVGLSNGKINYFVDSET  357
                + + Y+ + + +A   L++ +  +YFE    NYH+  + G + ++G   Y     +
Sbjct  299  QEPVAVISYQEVTNVSA--DLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLS  356

Query  358  FLNSASFKAYLESSkykkytyhykgtkVFLKKLGTEFNHVTYDLLLAAYLIQSSIGKQDF  417
            +L + SFK  ++ +       + K   V+L  LG E+   +YD  LA YL+ S++  +++
Sbjct  357  LLATDSFKQVFQKPIATYDFKRSK---VLLSHLGIELVAPSYDARLANYLL-STVEDNEL  412

Query  418  TFIAQQFQITDIQYDEEVYGKGAKKALPLIPSDYEGHIAKKAYIIHKLMQQTLDVLTERN  477
            + IA+ F    ++ D+ VYGKGAK+A+P        H+A+K  ++     Q LD LT ++
Sbjct  413  STIARIFTDISLEEDDTVYGKGAKRAVP-DKDVLLEHLARKVKVLLDSKSQMLDKLTAHE  471

Query  478  QLSLLNDVELPLSDVLADMEYQGLTVDLKELENQTKDMSLRIDKLRTEILLLAGVDFNVD  537
            QL L +++ELPL++VLA ME +G+ V+   L++ + +  + I+ L  EI  +AG +FN++
Sbjct  472  QLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNIN  531

Query  538  SPKQLGDVLFDTLGLP--NGKKTKTGYSTGIEVLNNLIDHHPIINLIIEYRQLTKLYSTY  595
            SPKQLG +LF+ + LP    KKTKTGYST+++VL+ L    PI+  I++YRQ+TKL STY
Sbjct  532  SPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTY  591

Query  596  LIGIKESVFEDNRVHTIYNQALTLTGRLSSLEPNLQNIPIRTEEGRQIRKLFIPEP-DSY  654
            +IG+++ ++ D ++HT Y Q LT TGRLSS++PNLQNIPIR E+GR IRK F P   D+ 
Sbjct  592  VIGLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAV  651

Query  655  FVGADYSQIELRVLAAMADVKNLKQAFEEDQDIHTVTAQKVFHVDT---VDSEQRRRAKA  711
            ++++DYSQIELRVLA +++  +L  AF+E+ DIHT TA +VF +D    V +++RR AKA
Sbjct  652  LLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKA  711

Query  712  VNFGIIYGIGPWSLSEDIGVTVKEAENFISRYLEVYPEIKDYMTNIVEFAKTHGYVETLL  771
            VNFGI+YGI+  +LS+++G+T K++ ++I  Y+E YP IK YM N+V  AK  GYVETL+
Sbjct  712  VNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLF  771

Query  772  NRRRYIPELSSKVFNLREFGKRTSLNAPIQGTAADIIKLAMIDLHNYLKDNKKKSKLILQ  831
            +RRR +P+++S+ FN+R F+ RT++N+PIQG+AADI+K+AMI+L++ L+    ++K++LQ
Sbjct  772  KRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQ  831

Query  832  VHDELIVEVVKEELDEMKEVIPNIMEKAFNLGVRLKTSCDVGNNWYELK  880
            VHDE+++EV ++EL  +K ++ + ME A +L+V L      G++WYE K
Sbjct  832  VHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

445) Tsac_2145 in NC_017992


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  554 bits (2092),  Expect = 8e-159, Method: Compositional matrix adjust.
 Identities = 376/891 (43%), Positives = 589/891 (67%), Gaps = 40/891 (4%)

Query  2    SKFLIIDGNSLMYRAYFAL----PDLMNSEGMHTNAIYGFSMMllklleeekPDYIAIAF  57
            +K+L+IDG+S+ +RA+FAL      + N  G+HTNAIYGF +ML  ++   +P  + +AF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  58   DKKAPTFRHKEYSAYKGTRQSMPEELIEQVDILKDVINAFNIKTIEIEGFEADDIIGTVS  117
            D    TFR   Y+ YK+ R   P+E+ EQ   +++++ A+ I   E+E +EADDIIGT+ 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  118  KIA--SESGMDVLIVTGDRDALQLVSANVKVKICKKGITQMDEYDEKAVFEKYEVTPLQF  175
            K+A  +E   DV IV+GD+D +QL   N  V I KKG+++ +E+    + EK  +TP QF
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  176  IDLKGLMGDKSDNIPGVPNIGEKTAIKLIKEFGSIENLLMNTDKLK-GKVKENVENNAEL  234
            IDLK+LMGDKSDNIPGV +IGEKT++KL+ EFGS+E +  + D +K +K+KEN+ N+ + 
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRDQ  244

Query  235  AVLSKRLATIERNVPIDIDLNEYAVKNYDANRLTELFEKLEFSSLISDLKDDSRDTKDIK  294
            A LSK LATI+   PI I+L++   +  D   L+++++ ++F  L  +L  +  +     
Sbjct  245  AFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQE----  300

Query  295  EWPVRDFTY--VKNVLGK-FDVLSLYPF-----IYDGKMKAVSFACGD-ESFFVEIDDYD  345
              PV  ++Y  V NV +  F    ++ F      Y+ +   ++FA G+ E ++   D   
Sbjct  301  --PVAVISYQEVTNVSADLFSAEDIFYFETLRDNYH-REAIIGFAWGHGEQIYASTD---  354

Query  346  NFKLLNNDKL------TLIGHDLKDFLVSISYCGIELNCKILDTAIMTYLLNPSESNYDI  399
             + LL  D +       +   D+K   V +S  GIEL     D+ +  YLL+  E N ++
Sbjct  355  -LSLLATDSFKQVFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDN-EL  412

Query  400  SRVLKKYLKEDLQNIDDIVGKGRNKKSYDDIDKRLLVDYMCSVASSLFKLKDKLMSFIKE  459
            S + + +    L++ D + GKG ++      DK +L++ +      L+  K +++  +  
Sbjct  413  STIARIFTDISLEEDDTVYGKGAKRAV---PDKDVLLEHLARKVKVLLDSKSQMLDKLTA  469

Query  460  MEMEDLLKNVEIPLIEVLKSMEVYGFTLDKDVLRSISKEIDEKTDKIVKDIYDAAGYEFN  519
             E  DL +N+E+PL +VL  ME+ G+ +++  L+ ++ +     + + ++IYD AG EFN
Sbjct  470  HEQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFN  529

Query  520  INSTKQLSEFLFDKLNLP--AIKKTKTGYSTDMEVLAELIPYNDIVGEIIEYRQLMKLKS  577
            INS KQL+ +LF+K++LP    KKTKTGYST ++VL  L P   IV+ I++YRQ+ KL+S
Sbjct  530  INSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQS  589

Query  578  TYIDGFIPIMDENNRVHSTFKQTVAATGRISSTEPNLQNIPVREEFGRRIRKAFVSSYED  637
            TY+ G+   +  + ++H+ + Q ++ TGR+SS +PNLQNIP+R E GR IRKAF +S ED
Sbjct  590  TYVIGLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHED  649

Query  638  GLIISADYSQIELRVLAHLSEDEKLIESFLNNEDIHLRTASEVFKVSKE-EVTSEMRRRA  696
            ++++S+DYSQIELRVLAH+S DE LI +F +  DIH  TA  VF + K  +VT++ RR A
Sbjct  650  AVLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNA  709

Query  697  KAVNFGIVYGISDYGLSKDLKISRKEAKEYIDNYFDRYKGVKNYIDSIVKFAKENGYVTT  756
            KAVNFGIVYGISD+GLS++L I+RK++K YID YF+RY G+K Y++++V+ AK++GYV T
Sbjct  710  KAVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVET  769

Query  757  ILNRRRYIPEINSKNFNQRSFGERMAMNTPIQGSAADIIKMSMVKVYNELKERGLKSRLI  816
            +++RRR +P+INS+NFN RSF+ER A+N+PIQGSAADI+K++M+++ + L+  G++++++
Sbjct  770  LFKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKML  829

Query  817  LQVHDELIIDTHPDEVEIVKGLLKSIMENVIKLRVPLVVDIGQGKNWYDAK  867
            LQVHDE++++   DE+  +K L+K  ME  + L VPL VD + G++WY+AK
Sbjct  830  LQVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

446) polA in NC_019954


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  548 bits (2069),  Expect = 6e-157, Method: Compositional matrix adjust.
 Identities = 384/900 (43%), Positives = 583/900 (65%), Gaps = 68/900 (7%)

Query  2    KKMLLIDGNSLLHRAFHAL----PPLRTSKGVHTNAVYGFLNMLFRILQEENPDYVTVAF  57
            +K+LLIDG+S+  RAF AL      ++   G+HTNA+YGF  ML ++++   P  V VAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  58   DKKGPTFRHDEYAAYKATRPKTPDELIGQFDILKEILKALNINFIEADGFEADDILGTIS  117
            D    TFR + YA YKA R+KTPDE+  QF  ++E+L AL I + E + +EADDI+GT+ 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  118  KKGEQEGI-FSI-IVTGDKDALQLVSSNTNVLLTKKGISEMETYDTEKVKSRYGIRPEAV  175
            K +E+  + F + IV+GDKD +QL   NT V ++KKG++E E +    +  + G+ P+  
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  176  ADMKGLMGDKSDNIPGVPGVGEKTAAKLIQEFKTLDNVLKNTDKLK-GKVRENLEKYAEQ  234
             D+K+LMGDKSDNIPGV  +GEKT+ KL++EF +L+ +  + D +K +K++ENL +  +Q
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRDQ  244

Query  235  AEASKYLATIVRDVPLEFNPDDIVYCEPDYDKLINLFRDLEFYSLIDRV--KIPANSIDT  292
            A  SK LATI    P+ +  DDIVY  PD   L +++ +++F  L   +  ++P +++  
Sbjct  245  AFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEPVAV  304

Query  293  KEFDTETTQNIEDNNALQKLVKKINSSKNI---AVLVDA-EKKDLVSYA---TDGIYISV  345
              ++  T  + +           + S+ +I     L D  ++  ++++A    + IY S 
Sbjct  305  ISYQEVTNVSAD-----------LFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYAST  353

Query  346  ENKCYFISHKLLKENSSISFLKQILEDT-AIYKITHDGKFTRNVLRQLGIDFRCQ-FDTM  403
            +         LL  +S    +KQ+++   A Y + +    ++ +L +LGI++    +D+ 
Sbjct  354  D-------LSLLATDS----FKQVFQKPIATYDFKR----SKVLLSHLGIELVAPSYDAR  398

Query  404  LAAYLLESSKPRYDIPILVMEYLGKTMSD-------------------IPSFDEKTSYLF  444
            LA YLL +     +++ +   + + ++ +                   +  +  K   L+
Sbjct  399  LANYLLSTVEDN-ELSTIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLL  457

Query  445  ELKKIMDEKIKDCLMDKLFYEVEMPFSVVLADMEHAGIKVDFAKLQELSERFGKKLAALT  504
            + K  M +K+       L+ ++E+P++ VLA ME  GIKV+ A LQ+++E+    + ALT
Sbjct  458  DSKSQMLDKLTAHEQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALT  517

Query  505  EEIYDLAGTEFNINSPKQLGEILFEKLSLP--VIKRTKTGYSTDAEVLEKLRPSHPIIEK  562
            +EIYD+AG EFNINSPKQLG ILFEK+ LP  + K+TKTGYST  +VLE+L P  PI+ K
Sbjct  518  QEIYDMAGQEFNINSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAK  577

Query  563  ILEYRFLMKMKSTYADGLSALVDKKTGRIYTSFNQTVTSTGRISSTEPNLQNIPVKTEEG  622
            IL+YR + K++STY  GL   +    G+I T + Q +T TGR+SS +PNLQNIP++ E+G
Sbjct  578  ILDYRQITKLQSTYVIGLQDYI-LADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQG  636

Query  623  KHIRGVFTSDGPGHVLLSGDYSQIELRVLAHMSQDPGLIEAFVSGEDIHRRTASEVFGVP  682
            + IR  FT+   + VLLS+DYSQIELRVLAH+S D  LI AF  G DIH  TA  VFG+ 
Sbjct  637  RLIRKAFTPSHEDAVLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGID  696

Query  683  -PEEVTPLLRDKAKAVNFGIIYGISDYGLAQNLGISNQEAKEYIDAYFARYPGVRDYIRE  741
             + +VT+  R +AKAVNFGI+YGISD+GL++NLGI+ +++K YID+YF RYPG++ Y+ +
Sbjct  697  KAADVTANDRRNAKAVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMEN  756

Query  742  TIRSAKALGYVTTLLNRRRYIPDINSRNYHLRSFAERTAVNTPIQGSAADIIKIAMVKVH  801
             +R AK  GYV TL++RRR +PDINSRN+++RSFAERTA+N+PIQGSAADI+KIAM++++
Sbjct  757  VVREAKDKGYVETLFKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLD  816

Query  802  DNLRQNNLKAKILLQVHDELILDVPEEELTAVKEILKQHMENAIPLRVPLVVDFKQGYNW  861
              L+   ++AK+LLQVHDE++L+VP++ELTA+K ++K+ ME A+ L VPL VD   G +W
Sbjct  817  KALQAGGFRAKMLLQVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSW  876

447) TepRe1_1612 in NC_015519


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  548 bits (2069),  Expect = 6e-157, Method: Compositional matrix adjust.
 Identities = 384/900 (43%), Positives = 583/900 (65%), Gaps = 68/900 (7%)

Query  2    KKMLLIDGNSLLHRAFHAL----PPLRTSKGVHTNAVYGFLNMLFRILQEENPDYVTVAF  57
            +K+LLIDG+S+  RAF AL      ++   G+HTNA+YGF  ML ++++   P  V VAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  58   DKKGPTFRHDEYAAYKATRPKTPDELIGQFDILKEILKALNINFIEADGFEADDILGTIS  117
            D    TFR + YA YKA R+KTPDE+  QF  ++E+L AL I + E + +EADDI+GT+ 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  118  KKGEQEGI-FSI-IVTGDKDALQLVSSNTNVLLTKKGISEMETYDTEKVKSRYGIRPEAV  175
            K +E+  + F + IV+GDKD +QL   NT V ++KKG++E E +    +  + G+ P+  
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  176  ADMKGLMGDKSDNIPGVPGVGEKTAAKLIQEFKTLDNVLKNTDKLK-GKVRENLEKYAEQ  234
             D+K+LMGDKSDNIPGV  +GEKT+ KL++EF +L+ +  + D +K +K++ENL +  +Q
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRDQ  244

Query  235  AEASKYLATIVRDVPLEFNPDDIVYCEPDYDKLINLFRDLEFYSLIDRV--KIPANSIDT  292
            A  SK LATI    P+ +  DDIVY  PD   L +++ +++F  L   +  ++P +++  
Sbjct  245  AFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEPVAV  304

Query  293  KEFDTETTQNIEDNNALQKLVKKINSSKNI---AVLVDA-EKKDLVSYA---TDGIYISV  345
              ++  T  + +           + S+ +I     L D  ++  ++++A    + IY S 
Sbjct  305  ISYQEVTNVSAD-----------LFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIYAST  353

Query  346  ENKCYFISHKLLKENSSISFLKQILEDT-AIYKITHDGKFTRNVLRQLGIDFRCQ-FDTM  403
            +         LL  +S    +KQ+++   A Y + +    ++ +L +LGI++    +D+ 
Sbjct  354  D-------LSLLATDS----FKQVFQKPIATYDFKR----SKVLLSHLGIELVAPSYDAR  398

Query  404  LAAYLLESSKPRYDIPILVMEYLGKTMSD-------------------IPSFDEKTSYLF  444
            LA YLL +     +++ +   + + ++ +                   +  +  K   L+
Sbjct  399  LANYLLSTVEDN-ELSTIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLL  457

Query  445  ELKKIMDEKIKDCLMDKLFYEVEMPFSVVLADMEHAGIKVDFAKLQELSERFGKKLAALT  504
            + K  M +K+       L+ ++E+P++ VLA ME  GIKV+ A LQ+++E+    + ALT
Sbjct  458  DSKSQMLDKLTAHEQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALT  517

Query  505  EEIYDLAGTEFNINSPKQLGEILFEKLSLP--VIKRTKTGYSTDAEVLEKLRPSHPIIEK  562
            +EIYD+AG EFNINSPKQLG ILFEK+ LP  + K+TKTGYST  +VLE+L P  PI+ K
Sbjct  518  QEIYDMAGQEFNINSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAK  577

Query  563  ILEYRFLMKMKSTYADGLSALVDKKTGRIYTSFNQTVTSTGRISSTEPNLQNIPVKTEEG  622
            IL+YR + K++STY  GL   +    G+I T + Q +T TGR+SS +PNLQNIP++ E+G
Sbjct  578  ILDYRQITKLQSTYVIGLQDYI-LADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQG  636

Query  623  KHIRGVFTSDGPGHVLLSGDYSQIELRVLAHMSQDPGLIEAFVSGEDIHRRTASEVFGVP  682
            + IR  FT+   + VLLS+DYSQIELRVLAH+S D  LI AF  G DIH  TA  VFG+ 
Sbjct  637  RLIRKAFTPSHEDAVLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGID  696

Query  683  -PEEVTPLLRDKAKAVNFGIIYGISDYGLAQNLGISNQEAKEYIDAYFARYPGVRDYIRE  741
             + +VT+  R +AKAVNFGI+YGISD+GL++NLGI+ +++K YID+YF RYPG++ Y+ +
Sbjct  697  KAADVTANDRRNAKAVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMEN  756

Query  742  TIRSAKALGYVTTLLNRRRYIPDINSRNYHLRSFAERTAVNTPIQGSAADIIKIAMVKVH  801
             +R AK  GYV TL++RRR +PDINSRN+++RSFAERTA+N+PIQGSAADI+KIAM++++
Sbjct  757  VVREAKDKGYVETLFKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLD  816

Query  802  DNLRQNNLKAKILLQVHDELILDVPEEELTAVKEILKQHMENAIPLRVPLVVDFKQGYNW  861
              L+   ++AK+LLQVHDE++L+VP++ELTA+K ++K+ ME A+ L VPL VD   G +W
Sbjct  817  KALQAGGFRAKMLLQVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSW  876

448) Dred_1599 in NC_009253


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  543 bits (2050),  Expect = 2e-155, Method: Compositional matrix adjust.
 Identities = 380/911 (42%), Positives = 612/911 (68%), Gaps = 68/911 (7%)

Query  4    DTIIIIDGNSLIHRAF----HAIPLLSNSKGVITNAVYGFTNMVLKVIKEQEPGLVAVAF  59
            + +++IDG+S+  RAF    + I  + N  G+ TNA+YGF  M+  ++K   P  V VAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  60   DKGKTTFRNQEYAAYKGTRKATPDELRPQFILARDILGAMRIPFFELDGFEADDLIGTIA  119
            D GKTTFR + YA YK+ R  TPDE+R QF   R++L A+ I+++EL+ +EADD+IGT+ 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  120  CQAEATG--LNVLILTGDRDALQLVSPKTKVMLTRKGITEIDLFDEGKVWDKYGVTPSQV  177
              AE T   ++V I++GD+D +QL   +T V +++KG++E++ F  + + +K G+TP+Q 
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  178  VDLKGLQGDTSDNIPGVAGIGEKTASVLIKEYGSVEEILKNID--KLSPRHQKLLRGNEE  235
            +DLK+L GD SDNIPGV+ IGEKT+  L+ E+GS+E I  +ID  K S   ++L+ + ++
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRDQ  244

Query  236  IALLSKKLATIIRDVPMELDLSECSWHGPDNQKLLEIAKELEFKTLIKQLTSGQKFIKQS  295
             A+LSK LATI    P+ ++L +   +GPD   L ++  E++F  L K L+S     + +
Sbjct  245  -AFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLAS-----QMP  298

Query  296  QDSGTSADLPPLETYQVGYLNVTDQDALDELLIEVSRQGKVAIYLEGLRNQGIDTAYLAM  355
            Q++ +           ++Y +VT+  A  +L+      +   +Y+E LR++    A ++ 
Sbjct  299  QEPVAV----------ISYQEVTNVSA--DLF-----SAEDIFYFETLRDNYHREAIIGF  341

Query  356  ---EDHDIYRLAIQNKDSDSDPCLTVLKAICEC--ESVKKYFHDAKQALWMLHHHSIELK  410
               ++++IY        + +D  L    ++ +    ++  Y  D K++  +L H +IEL 
Sbjct  342  AWGHGEQIY--------ASTDLSLLATDSFKQVFQKPIATY--DFKRSKVLLSHLGIELV  391

Query  411  ALAADTMVSAYLLNPTASNYDIN-------DVALEHLGMVLPAEGETAMASRAEAIRRLA  463
            A + D+ ++ YLL+    N +++       D++LE+ + V    +  A++ +   + +LA
Sbjct  392  APSYDARLANYLLSTVEDN-ELSTIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLA  450

Query  464  QK----------LFEKLAERQEDRLLTQVELPLVRILSEMEIAGVAVDKQGLQDMSvelq  513
            +K          +++KL+ +++  L  ++ELPL  +L+ MEI G+ V++  LQDM+ + +
Sbjct  451  RKVKVLLDSKSQMLDKLTAHEQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNK  510

Query  514  tvtetlttKIHELAGENFNINSPKQLGPILFEklkl--pvlkktktGYSTDAEVLEKLAE  571
             + E+LT  I ++AG++FNINSPKQLG+ILFEK++L   + KKTKTGYST  +VLE+LA 
Sbjct  511  VIIEALTQEIYDMAGQEFNINSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAP  570

Query  572  EHEIVALILEYRQMAKLKSTYTDGLAALVDPQTGRLHSTFHQTVTATGRLSSAEPNLQNI  631
               IVA IL+YRQ++KL+STY  GL   + ++ G++H+ + Q +T TGRLSS +PNLQNI
Sbjct  571  IAPIVAKILDYRQITKLQSTYVIGLQDYILAD-GKIHTRYVQDLTQTGRLSSVDPNLQNI  629

Query  632  PIRLETGRKIRKVFIPRQRGNLILTADYSQIELRVLAHMSQDESFLDAFRQGQDIHTRTA  691
            PIRLE GR IRK F P + + ++L++DYSQIELRVLAH+S DE ++ AF +G DIHT TA
Sbjct  630  PIRLEQGRLIRKAFTPSHEDAVLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTA  689

Query  692  SEVFGVPMD-QVTSEMRSRAKAVNFGIVYGISDFGLARDLKVSRKEAQGYIDHYFARCPG  750
              VFG+    +VT++ R  AKAVNFGIVYGISDFGL+ +L ++RK++++YID YF R PG
Sbjct  690  MRVFGIDKAADVTANDRRNAKAVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPG  749

Query  751  VRQYIDRVIKEAKETGYVNTLLNRRRYLPELFSKNFNIRNFGERAAMNTPIQGTAADIIK  810
            ++ Y++ V++EAK+ GYV+TL++RRR LP++ S+NFN+R+F+ER+A+N+PIQG+AADI+K
Sbjct  750  IKAYMENVVREAKDKGYVETLFKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILK  809

Query  811  LAMVKISQQLKEQNLSSQMVLQVHDELIFDAPENEIESLIMLVRQSMENALQLDVPLVVD  870
            +AM+++ + L+   + ++M+LQVHDE++++ P++E+ ++  LV+++ME A++L VPL VD
Sbjct  810  IAMINLDKALQAGGFRAKMLLQVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVD  869

Query  871  IKLGPNWYEAK  881
               G +WYEAK
Sbjct  870  ESTGQSWYEAK  880

449) STH848 in NC_006177


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  542 bits (2047),  Expect = 3e-155, Method: Compositional matrix adjust.
 Identities = 384/905 (43%), Positives = 586/905 (65%), Gaps = 64/905 (7%)

Query  1    MPKPEKLLLLDGNSLANRAFYAL----RLFSTSDGVYTNAVYGFLTMLFKLLDEEQPDYV  56
            M + +KLLL+DG+S+A RAF+AL      F    G+ TNA+YGF  ML  ++   +P  V
Sbjct  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60

Query  57   AVAFDKGRQTFRTALYEDYKATRKAPPDEFRPQLDLLREVLTALNIPWFRVENYEADDIM  116
             VAFD G+ TFRT +Y DYKA R   PDEFR Q+  +RE+LTAL I+ + +E+YEADDI+
Sbjct  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120

Query  117  GTLARQA--AAEGLHTLIVTGDRDALQLISDRVTVVMTKKGITETVRYDPETLKAEYGLT  174
            GTL + A  +   ++  IV+GD+D +QL  +   V ++KKG++E   + P  L    GLT
Sbjct  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180

Query  175  PSQIIDLKALMGDASDNIPGVPGVGEKTALKLLADYGTVDGVYAHLDEIKGA-LQAKLRE  233
            P+Q+IDLKALMGD SDNIPGV  +GEKT+LKLL ++G+++G+Y H+D +K + ++ +L +
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  234  NRDKAELSRTLATINLDAPVTFDREALRRREPNYPQAYALFQRLEFKSL---LSRVTPPD  290
            +RD+A LS+TLATIN  +P+T++ + +    P+ +    +++ ++F  L   L+   P +
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQE  300

Query  291  GTVaaealaeqagaaqVEIVAARVVDRPGALRLSGQAPVLARMTADPGNPGRPRPVGLAM  350
                            V +++ + V   +A  +S++        +  +N  R   +G+A 
Sbjct  301  P---------------VAVISYQEVTNVSADLFSAEDIFY--FETLRDNYHREAIIGFA-  342

Query  351  GDPPAWLEGEALADPAEL--LDSGA-RLVGHDLKPLYNW------LYSQGIEPPAPAFDT  401
                 W +GE +  +++L  L +++ + V +   + Y+       L   GIE  AP++D+
Sbjct  343  -----WGHGEQIYASTDLSLLATDSFKQVFQKPIATYDFKRSKVLLSHLGIELVAPSYDA  397

Query  402  ALAAYLLDPSRSSYDLADLCRQHGLGELPPGDTP----------------DLWATRASVL  445
             LA YLL     + +L+ + R      L  +DT                 +  A +  VL
Sbjct  398  RLANYLLSTVEDN-ELSTIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVL  456

Query  446  PELHRRMEAELAAQGVDRLYREVELPLMPILAEMEAVGVGIDPAALHEMSVELERRILQV  505
             +   +M   L+A+    LY+++ELPL  +LA ME  G+ ++ A+L++M+ +    I  +
Sbjct  457  LDSKSQMLDKLTAHEQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEAL  516

Query  506  SQEIYELAGMQFNISSPKQLGDVLFGKLGLP--SGKKTKSGGYSTDAEVLEELAAAYPIA  563
            +QEIY++AG +FNI+SPKQLG +LF K+ LP    KKTK+G YST  +VLE LA+  PI 
Sbjct  517  TQEIYDMAGQEFNINSPKQLGSILFEKMQLPLEMTKKTKTG-YSTAVDVLERLAPIAPIV  575

Query  564  ARVLDYRTLTKLKGTYVDALGQLIARDGRIHTTFAQTVAETGRLSSKDPNLQNipiriee  623
            A++LDYR +TKL++TYV +L + I  DG+IHT + Q +++TGRLSS DPNLQNIPIR+E+
Sbjct  576  AKILDYRQITKLQSTYVIGLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQ  635

Query  624  grrirKAFV-ARPGCVLLSADYSQIELRVVAHFSGDPALREAFLHDQDIHTRTAAEVFGV  682
            GR IRKAF  ++ + VLLS+DYSQIELRV+AH+SGD  L  AF ++ DIHT TA  VFG+
Sbjct  636  GRLIRKAFTPSHEDAVLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGI  695

Query  683  PMD-QVTPEMRRQAKAVNFGLIYGQTDFGLARSVGISRAEARAFIETYFAKFAGVRRYME  741
                +VT++ RR+AKAVNFG++YG +DFGL+ ++GI+R +++++I+TYF +++G++ YME
Sbjct  696  DKAADVTANDRRNAKAVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYME  755

Query  742  EKKAEAREKGYVTTLDGRRRPLPEINHRVFTIRQNAERMAINTPIQGTAADLMKRAMIAV  801
            +   EA++KGYV TL  RRR LP+IN R F +R  AER AIN+PIQG+AAD++K AMI +
Sbjct  756  NVVREAKDKGYVETLFKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINL  815

Query  802  RRAMREEGLSARMILQVHDELVFECPVGEVDRLARLVRREMEGAMKLDVPLKVEVKVGPD  861
             +A++  G+ A+M+LQVHDE+V+E P +E+  + +LV+  ME+A+ L VPL V+   G  
Sbjct  816  DKALQAGGFRAKMLLQVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQS  875

Query  862  WYSVQ  866
            WY  +
Sbjct  876  WYEAK  880

450) polA in NC_008261


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  542 bits (2045),  Expect = 4e-155, Method: Compositional matrix adjust.
 Identities = 386/893 (44%), Positives = 600/893 (68%), Gaps = 45/893 (5%)

Query  2    KRLLILDGNSLLNRAFYA----VPLLSNSEGTHTNAIYGFTNMLFKMREDIKPDYIVCTF  57
            ++LL++DG+S+  RAF+A    +  + N  G HTNAIYGF  ML  M   ++P  ++ +F
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  58   DKKAPTFRHLEYGDYKAGRKKMPPELAEQFPIVKEMLKLFSITTYELDGFEADDIIGSLA  117
            D    TFR   Y+DYKAGR K P E+ EQF+ ++EML  ++I+ YEL+ +EADDIIG+L 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  118  KVAEGEGI--EVYIMTGDKDALQLAAKDINVCITKKGVSEIEVYNYDRMVEEYGVTPTQF  175
            K+AE   +  +V I++GDKD +QL+  +  V I+KKGV+E+E +    ++E  G+TP QF
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  176  IDVKGLMGDKSDNIPGVPGVGEKTAFKLIKEYGSVEAVLENIDNISGKKLKENLTEYSEQ  235
            ID+K+LMGDKSDNIPGV  +GEKT++KL+ E+GS+E++ E+ID +   K+KENL +  +Q
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRDQ  244

Query  236  AIFSKKLATIMTNVPIDFDLDEIKSKDDYNKDQLKALFTKLQMKSILDKLSNGeeeepei  295
            A++SK LATI T  PI ++LD+I  ++  +   L  ++  ++   +   L++   +EP  
Sbjct  245  AFLSKTLATINTASPITIGLDDIVYNGP-DVASLSQFYDEMDFVQLKKGLASQMPQEPVA  303

Query  296  eVKITNIENSKELEELFKNINEEVYINFTYLNKEKYSTIEIDKIFINYDEKNYLINFKEL  355
             +   ++ N     +LF    E+++  F  L +++Y    I  +    +E+ Y      L
Sbjct  304  VISYQEVTNVSA--DLFSA--EDIFY-FETL-RDNYHREAIIGFAWGHGEQIYASTDLSL  357

Query  356  VKEEENIKSFKEFFENEDILKNGYSIKNALTALKKLGIDFNGLAFDCELAAYLIDSSKGE  415
            +  +    SFK+ F++       Y +K +   L  LGI++ + ++D  LA YL+ +  ++
Sbjct  358  LATD----SFKQVFQKP---IATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDN  410

Query  416  --------YTLLSLINN---YLSKFPNVKEGEEDLVGISFMKELTLVLKKKIEEEKMERL  464
                    +T +SL ++   Y +K ++    + D++   + + + ++L  K   + +++L
Sbjct  411  ELSTIARIFTDISLEEDDTVY-GKGAKRAVPDKDVLLEHLARKVKVLLDSK--SQMLDKL  467

Query  465  -------MY-DIELPLETVLSSMESIGFKVNKNILDELSIKFKRELEETQKEIFELADEE  516
                   +Y +IELPL  VL+ ME  G+KVN+  L++++ + K  +E   +EI+++A++E
Sbjct  468  TAHEQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQE  527

Query  517  FNINSPKQLGKILFEKLDLP--VIKKTKTGYSTNAEVLEKLKDKHPIIEKITYFRQLSKI  574
            FNINSPKQLG ILFEK++LP  + KKTKTGYST  +VLE+L    PI+ KI  +RQ++K+
Sbjct  528  FNINSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKL  587

Query  575  YSTYVEGLKSVIDTDGSIHSTFNQTVTTTGRLSSTEPNLQNIPIKYEMGREIRKVFIPKE  634
             STYV GL+  I +DG IH+ + Q +T TGRLSS +PNLQNIPI+ E GR IRK F P +
Sbjct  588  QSTYVIGLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSH  647

Query  635  EGDLLISADYSQIELRVLAHISGDENMIDAFNHHSDIHTKTASEVFKVP-VEEVTPLMRS  693
            E+ +L+S+DYSQIELRVLAHISGDE++I AFN+ +DIHT TA  VF +    +VT+  R 
Sbjct  648  EDAVLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRR  707

Query  694  RAKAVNFGIVYGIGDFSLSQDLNISRKEAKEYMDIYFERYPKIKEYISKVIHEAQTKGYV  753
             AKAVNFGIVYGI+DF+LS++L I+RK++K Y+D YFERYP IK Y+ +V++EA+ KGYV
Sbjct  708  NAKAVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYV  767

Query  754  LTMLNRRRYIPEANSSNKIVKALGERLAMNAPIQGTAADIIKLAMVNVYnklkelnlnsk  813
             T+++RRR +P+ NS N  V++++ER A+N+PIQG+AADI+K+AM+N+ + L+   + +K
Sbjct  768  ETLFKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAK  827

Query  814  lilQVHDELIINVVKGELDIVKKLLKEEMENTIKLSVPLDVDVNVGEDWYKLK  866
            ++LQVHDE++++V ++EL  +KKL+K+ ME ++ L+VPL VD + G+ WY  K
Sbjct  828  MLLQVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

451) Hore_04860 in NC_011899


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  541 bits (2041),  Expect = 8e-155, Method: Compositional matrix adjust.
 Identities = 382/891 (43%), Positives = 586/891 (66%), Gaps = 49/891 (5%)

Query  2    KKKLYLLDGQSLAHRAFYAL----PLLSTSRGEYTNAVFGFTRMllklldeekpdlIAVA  57
            K+KL L+DG S+A RAF+AL      +    G  TNA++GF  ML  ++   +P  + VA
Sbjct  4    KNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVA  63

Query  58   FDKKAPTFRHKEYKEYKAHRKKMPEELKPQLSLIKEVLKSFSIPIIEIEGFEADDIIGTM  117
            FD    TFR   Y +YKA R K P+E++ Q+S I+E+L +++I+  E+E +EADDIIGT+
Sbjct  64   FDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTL  123

Query  118  ARKGE--EEGFEVVIVTGDRDALQLVTEDVSVMYTKRGISDIVRYDLNKVRERYELEPQQ  175
             + +E  E  F+V IV+GD+D +QL  E+  V  +K+G++++  +    + E+  L P+Q
Sbjct  124  DKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQ  183

Query  176  LIDMKGLMGDSSDNIPGVPGIGEKTAIKLLKEFSSLEEILDNIDKVSGKKRKENLQKYAD  235
            +ID+K+LMGD SDNIPGV  IGEKT++KLL EF+SLE I ++ID     K KENL +  D
Sbjct  184  FIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRD  243

Query  236  QARLSKRLGEIKVDVPLDVELDECHLGKFHKKNIRELFERLEFASLLNRFKEKTSISIDD  295
            QA LSK L+ I+   P+ + LD+      +  ++ ++++ ++F  L      K +++  +
Sbjct  244  QAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQL------KKGLA-SQ  296

Query  296  ISVKELDRKGLENICDKARNLGKLGLTLRLNNYTTPVRAH-ASQGIISL--GEGN-LYIF  351
            ++   +   + +++ + + +L      +    Y   +R +   ++II++  G+G+ +Y  
Sbjct  297  MPQEPVAVISYQEVTNVSADLFSAEDIF----YFETLRDNYHREAIIGFAWGHGEQIYAS  352

Query  352  TDINE-AISILKPILTDISVKKYILNSKECTVFLKKHDIELEGLVFDPLLAYYLLKP--S  408
            TD++  A   +K ++   ++  Y  + K   V+L   +IEL +  +D+ LA YLL     
Sbjct  353  TDLSLLATDSFKQVFQK-PIATY--DFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED  409

Query  409  GKLPGLRDLLDQELSLSLPED-----------IKEDNLYLVFMDNIFKL----AEGMVPK  453
              L+ +  ++ +   +SL ED           + + ++ L  +    K+       M+ K
Sbjct  410  NELSTIARIFTD---ISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDK  466

Query  454  LEDMELIELFNDIEIPLITVLAELEYNGIKVDAEYLESLSRKWEEELNGLESKIHELAGE  513
            L   E ++L+++IE+PL  VLA +E +GIKV+   L+ ++ +    +++L   I ++AG+
Sbjct  467  LTAHEQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQ  526

Query  514  KFNINSPKQLGGILFEKLGLP--VIKKTKTGYSTGAKVLEKLEDKHPIIPLISEYRQLMK  571
             FNINSPKQLG+ILFEK+ LP  + KKTKTGYST+  VLE+L    PI++ I +YRQ+ K
Sbjct  527  EFNINSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITK  586

Query  572  LKSTYVDALPPMINPDTGRLHTSFNQMVTATGRLSSTEPNLQNIPVRTDEGREIRRAFIT  631
            L+STYV +L   I +D G++HT + Q +T TGRLSS +PNLQNIP+R ++GR IR+AF  
Sbjct  587  LQSTYVIGLQDYILAD-GKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTP  645

Query  632  ENEDWVLLAADYSQIELRVLAHISDDEGLKAAFNTGQDIHTQTASEVFEVE-PDEVTPNM  690
             +ED VLL++DYSQIELRVLAHIS+DE L AAFN G DIHT TA  VF ++ + +VT+N 
Sbjct  646  SHEDAVLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTAND  705

Query  691  RRHAKVINFGIAYGMSPYGLARDLGISRQEASDYINKYFERFTGVKDYMERVVTEAKTKG  750
            RR+AK +NFGI YG+S +GL+ +LGI+R+++  YI+ YFER+ G+K YME VV EAK KG
Sbjct  706  RRNAKAVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKG  765

Query  751  YVTTIFNRRRYIPEINSRNYHRRSFAERTAINTPIQGTAADIMKLAMIKVYNRLKENGSP  810
            YV T+F+RRR +P+INSRN++ RSFAERTAIN+PIQG+AADI+K+AMI++ + L+  G  
Sbjct  766  YVETLFKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFR  825

Query  811  ARILLQVHDELILEVPREDLTEMARIVKSEMEKAVDMKVPLVVNLESGPNW  861
            A++LLQVHDE++LEVP ++LT + ++VK  ME AVD+ VPL V+  +G +W
Sbjct  826  AKMLLQVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSW  876

452) polA in NC_003366


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  541 bits (2041),  Expect = 9e-155, Method: Compositional matrix adjust.
 Identities = 385/890 (44%), Positives = 598/890 (68%), Gaps = 45/890 (5%)

Query  2    KRLLILDGNSLLNRAFYA----VPLLSNSEGTHTNAIYGFTNMLFKMREDIKPDYIVCTF  57
            ++LL++DG+S+  RAF+A    +  + N  G HTNAIYGF  ML  M   ++P  ++ +F
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  58   DKKAPTFRHLEYGDYKAGRKKMPPELAEQFPIVKEMLKLFSITTYELDGFEADDIIGSLA  117
            D    TFR   Y+DYKAGR K P E+ EQF+ ++EML  ++I+ YEL+ +EADDIIG+L 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  118  KVAEGEGI--EVYIMTGDKDALQLAAKDINVCITKKGVSEIEVYNYDRMVEEYGVTPTQF  175
            K+AE   +  +V I++GDKD +QL+  +  V I+KKGV+E+E +    ++E  G+TP QF
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  176  IDVKGLMGDKSDNIPGVPGVGEKTAFKLIKEYGSVEAVLENIDNISGKKLKENLTEYSEQ  235
            ID+K+LMGDKSDNIPGV  +GEKT++KL+ E+GS+E++ E+ID +   K+KENL +  +Q
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRDQ  244

Query  236  AIFSKKLATIMTNVPIDFDLDEIKSKDDYNKDQLKALFTKLQMKSILDKLSNGeeeepei  295
            A++SK LATI T  PI ++LD+I  ++  +   L  ++  ++   +   L++   +EP  
Sbjct  245  AFLSKTLATINTASPITIGLDDIVYNGP-DVASLSQFYDEMDFVQLKKGLASQMPQEPVA  303

Query  296  eVKITNIENNKELEDLFKNINEEVYINFTYLNKEKYSTIEIDKIFINYDEKNYLINFKEL  355
             +   ++ N     DLF    E+++  F  L +++Y    I  +    +E+ Y      L
Sbjct  304  VISYQEVTNVSA--DLFSA--EDIFY-FETL-RDNYHREAIIGFAWGHGEQIYASTDLSL  357

Query  356  VKEEENIKSFKEFFENEAILKNGYSIKNALTALKKLGIDFNGLAFDCELAAYLIDSSKGE  415
            +  +    SFK+ F++       Y +K +   L  LGI++ + ++D  LA YL+ +  ++
Sbjct  358  LATD----SFKQVFQKPI---ATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDN  410

Query  416  --------YTLLSLINN---YLSKFPNVKEGEEDLVGITFMKELTLVLKKKIEEEKMERL  464
                    +T +SL ++   Y +K ++    + D++   + + + ++L  K   + +++L
Sbjct  411  ELSTIARIFTDISLEEDDTVY-GKGAKRAVPDKDVLLEHLARKVKVLLDSK--SQMLDKL  467

Query  465  -------MY-DIELPLETVLSSMESIGFKVNKDILDELSIKFKRELEETQKEIFELADEE  516
                   +Y +IELPL  VL+ ME  G+KVN+  L++++ + K  +E   +EI+++A++E
Sbjct  468  TAHEQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQE  527

Query  517  FNINSPKQLGKILFEKLDLP--VIKKTKTGYSTNAEVLEKLKDKHPIIEKITYFRQLSKI  574
            FNINSPKQLG ILFEK++LP  + KKTKTGYST  +VLE+L    PI+ KI  +RQ++K+
Sbjct  528  FNINSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKL  587

Query  575  YSTYVEGLKAVIDTDGSIHSTFNQTVTTTGRLSSTEPNLQNIPIKYEMGREIRKVFIPKK  634
             STYV GL+  I +DG IH+ + Q +T TGRLSS +PNLQNIPI+ E GR IRK F P  
Sbjct  588  QSTYVIGLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSH  647

Query  635  EGDLLISADYSQIELRVLAHISGDENMIDAFNHHSDIHTKTASEVFKVP-VEEVTPLMRS  693
            E+ +L+S+DYSQIELRVLAHISGDE++I AFN+ +DIHT TA  VF +    +VT+  R 
Sbjct  648  EDAVLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRR  707

Query  694  RAKAVNFGIVYGIGDFSLSQDLNISRKEAKEYMDIYFERYPKIKEYISKVIHEAQTKGYV  753
             AKAVNFGIVYGI+DF+LS++L I+RK++K Y+D YFERYP IK Y+ +V++EA+ KGYV
Sbjct  708  NAKAVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYV  767

Query  754  LTMLNRRRYIPEANASNKIVKALGERLAMNAPIQGTAADIIKLAMVNVYnklkelnlnsk  813
             T+++RRR +P+ N+ N  V++++ER A+N+PIQG+AADI+K+AM+N+ + L+   + +K
Sbjct  768  ETLFKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAK  827

Query  814  lilQVHDELIINVVKGELDIVKKLLKEEMENTIKLSVPLDVDVNVGEDWY  863
            ++LQVHDE++++V ++EL  +KKL+K+ ME ++ L+VPL VD + G+ WY
Sbjct  828  MLLQVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWY  877

453) polA in NC_008262


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  539 bits (2036),  Expect = 2e-154, Method: Compositional matrix adjust.
 Identities = 386/894 (44%), Positives = 603/894 (68%), Gaps = 47/894 (5%)

Query  2    KRLLILDGNSLLNRAFYA----VPLLSNSEGTHTNAIYGFTNMLFKMREDIKPDYIVCTF  57
            ++LL++DG+S+  RAF+A    +  + N  G HTNAIYGF  ML  M   ++P  ++ +F
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  58   DKKAPTFRHLEYGDYKAGRKKMPPELAEQFPIVKEMLKLFSITTYELDGFEADDIIGSLA  117
            D    TFR   Y+DYKAGR K P E+ EQF+ ++EML  ++I+ YEL+ +EADDIIG+L 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  118  KVAEGEGI--EVYIITGDKDALQLAAKDINVCITKKGVSEIEVYNYDRMVEEYGVTPTQF  175
            K+AE   +  +V I++GDKD +QL+  +  V I+KKGV+E+E +    ++E  G+TP QF
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  176  IDVKGLMGDKSDNIPGVPGVGEKTAFKLIKEYGSVEAVLENIDNISGKKLKENLTEYSEQ  235
            ID+K+LMGDKSDNIPGV  +GEKT++KL+ E+GS+E++ E+ID +   K+KENL +  +Q
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRDQ  244

Query  236  AIFSKKLATIMTNVPIDFDLDEIKSKDDYNKDQLKALFTKLQMKSILDKLSNGeeeepei  295
            A++SK LATI T  PI ++LD+I  ++  +   L  ++  ++   +   L++   +EP  
Sbjct  245  AFLSKTLATINTASPITIGLDDIVYNGP-DVASLSQFYDEMDFVQLKKGLASQMPQEPVA  303

Query  296  eVKITNIENNKKLEDLFNNINEEVYINFTYLNKEKYSTIEIDKIFINYDEKNYL-INFKE  354
             +   ++ N     DLF+   E+++  F  L +++Y    I  +    +E+ Y   ++  
Sbjct  304  VISYQEVTNVS--ADLFSA--EDIFY-FETL-RDNYHREAIIGFAWGHGEQIYASTDLSL  357

Query  355  LAQEEENIKALKEFFENEDILKNGYSIKNALTALKKLGIEFKGLAFDCELAAYLIDSSKG  414
            LA +     ++K+ F++       Y +K +   L  LGIE+ + ++D  LA YL+ +  +
Sbjct  358  LATD-----SFKQVFQKP---IATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED  409

Query  415  E--------YTLLSLINN---YLSKFPNVKDGEEDLVGISFMKELTLVLKKKIEEEKMER  463
            +        +T +SL ++   Y +K ++    + D++   + + + ++L  K   + +++
Sbjct  410  NELSTIARIFTDISLEEDDTVY-GKGAKRAVPDKDVLLEHLARKVKVLLDSK--SQMLDK  466

Query  464  L-------MY-DIELPLETVLSSMESIGFKVNKDILDELSIKFKRELEETQKEIFELADE  515
            L       +Y +IELPL  VL+ ME  G+KVN+  L++++ + K  +E   +EI+++A++
Sbjct  467  LTAHEQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQ  526

Query  516  EFNINSPKQLGKILFEKLDLP--VIKKTKTGYSTNAEVLEKLKDKHPIIEKITYFRQLSK  573
            EFNINSPKQLG ILFEK++LP  + KKTKTGYST  +VLE+L    PI+ KI  +RQ++K
Sbjct  527  EFNINSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITK  586

Query  574  IYSTYVEGLKSVIDTDGSIHSTFNQTVTTTGRLSSTEPNLQNIPIKYEMGREIRKVFIPK  633
            + STYV GL+  I +DG IH+ + Q +T TGRLSS +PNLQNIPI+ E GR IRK F P 
Sbjct  587  LQSTYVIGLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPS  646

Query  634  EEGDLLISADYSQIELRVLAHISGDENMIDAFNHHSDIHTKTASEVFKVP-VEEVTPLMR  692
            +E+ +L+S+DYSQIELRVLAHISGDE++I AFN+ +DIHT TA  VF +    +VT+  R
Sbjct  647  HEDAVLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDR  706

Query  693  SRAKAVNFGIVYGIGDFSLSQDLNISRKEAKEYMDIYFERYPKIKEYISKVIHEAQTKGY  752
              AKAVNFGIVYGI+DF+LS++L I+RK++K Y+D YFERYP IK Y+ +V++EA+ KGY
Sbjct  707  RNAKAVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGY  766

Query  753  VLTMLNRRRYIPEANASNKIVKALGERLAMNAPIQGTAADIIKLAMVNVYnklkelnlns  812
            V T+++RRR +P+ N+ N  V++++ER A+N+PIQG+AADI+K+AM+N+ + L+   + +
Sbjct  767  VETLFKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRA  826

Query  813  klilQVHDELIINVVKGELDIVKKLLKEEMENTIKLSVPLDVDVNVGEDWYKLK  866
            K++LQVHDE++++V ++EL  +KKL+K+ ME ++ L+VPL VD + G+ WY  K
Sbjct  827  KMLLQVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

454) Dtox_2415 in NC_013216


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  538 bits (2029),  Expect = 8e-154, Method: Compositional matrix adjust.
 Identities = 391/907 (44%), Positives = 591/907 (66%), Gaps = 57/907 (6%)

Query  9    AKNNTILVIDGNSLIHRAF----HAIPLLSTADGLPTNAVYGFTNMLLKILNDIQPKWVT  64
             ++N +L+IDG+S+  RAF    + I  +    GL TNA+YGF  ML  +++ ++P  V 
Sbjct  2    ENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVL  61

Query  65   VAFDKSKTTFRNQEYSEYKAHRKATPEELRPQFSLVKDVLNALSIKWLEAEGYEADDLIG  124
            VAFD +KTTFR + Y++YKA R  TP+E+R QFS ++++L AL+I   E E YEADD+IG
Sbjct  62   VAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIG  121

Query  125  TIVKKAEEEDA--DVVILSGDKDILQLVSDKTRAILTKKGITEIEEYNAENVYRKFGVHP  182
            T+ K AE  +   DV I+SGDKD++QL  ++T   ++KKG++E+EE+ +  +  K G+ P
Sbjct  122  TLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTP  181

Query  183  NQITDYKGLTGDPSDNIPGVPGIGPKTATKLLQDFDSVENILANLDKI-TSRARTLMENN  241
            NQ+ D K+L GD SDNIPGV  IG KT+ KLL++F+S+E I  ++D + TS+ +  + N+
Sbjct  182  NQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIND  241

Query  242  SEQALLSKRLATIITNVPVQITLEQCIRTEPNEAELFNILKKLEFKKLLRDMLTAETGNS  301
             +QA+LSK LATI T  P+ I L++ +   P+ A L ++   ++F +L +++ +    ++
Sbjct  242  RDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEP  301

Query  302  NQIKQKHLINKQSYAVEYITLSEQED---FEDLLVQAQKSGKVALALQGRREKGLISVAL  358
              +   + + + S       L   ED   FE L  + ++ + +++A  G+ E+   S  L
Sbjct  302  VAVISYQEVTNVS-----ADLFSAEDIFYFETLRDNYHREAIIGFAW-GHGEQIYASTDL  355

Query  359  CLSEGQNYLLPLNSSTETTSFALKLLQNICVDSKIKKCCYDTKADLWLLHYYGIEINQPG  418
             L   +++   ++ +  T                     YD K    LL   GIE+  P+
Sbjct  356  SLLATDSFKQVFQKPIAT---------------------YDFKRSKVLLSHLGIELVAPS  394

Query  419  FDVMLADYLLNP------GKSARSLPETALSHLDIVLQEGSETYLPASA---EVISRLVD  469
            +D  LA+YLL+       +  AR + + +L + D V   G+   +P      E ++R V 
Sbjct  395  YDARLANYLLSTVEDNELSTIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVK  454

Query  470  ILQS-------KLLLQEQENLYYDIELPLLKVLASMERTGVSVDKEQLQLMSEELNKKLQ  522
            +L         KL  +EQ +LY +IELPL +VLA ME  G+ V++  LQ M+E+ +  ++
Sbjct  455  VLLDSKSQMLDKLTAHEQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIE  514

Query  523  VLTTDIYEHAGEIFNINSTKQLGSILFEklkl--kagkktktgYSTDVTVLEELAGDHPV  580
             LT +IY+ AG+ FNINS KQLGSILFEK++L     KKTKTGYST V VLE LA   P+
Sbjct  515  ALTQEIYDMAGQEFNINSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPI  574

Query  581  VSLLLEYRQLAKLKSTYVDGLTGLINPQTGKLHTTFHQAVTATGRLSSSEPNLQNVPIRL  640
            V+ +L+YRQ++KL+STYV GL + I ++ GK+HT + Q +T TGRLSS +PNLQN+PIRL
Sbjct  575  VAKILDYRQITKLQSTYVIGLQDYILAD-GKIHTRYVQDLTQTGRLSSVDPNLQNIPIRL  633

Query  641  DAGRKIRKFFVPCKPDNFIFSADYSQIELRILAHIAQDNNLMDAFAKKQDIHTRTASEVF  700
            + GR IRK F P   D  ++S+DYSQIELR+LAHI+ D++L+ AF    DIHT TA  VF
Sbjct  634  EQGRLIRKAFTPSHEDAVLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVF  693

Query  701  GVAMD-EVTPEMRGRAKAVNFGIVYGISDFGLAKDIKVTRKEAGRYINNYFNRYSGVKAY  759
            G+    +VT++ R  AKAVNFGIVYGISDFGL++++ +TRK++  YI+ YF+RY+G+KAY
Sbjct  694  GIDKAADVTANDRRNAKAVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAY  753

Query  760  IDRVIREAREKGYVTTILNRRRYLPDLFSSNRVVRSFGERTAMNTPIQGSASDIIKLAMV  819
            ++ V+REA++KGYV T+++RRR LPD+ S N  VRSF+ERTA+N+PIQGSA+DI+K+AM+
Sbjct  754  MENVVREAKDKGYVETLFKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMI  813

Query  820  LIYREMRKRKLSSTMILQVHDELIFDVVASEVEEMQNLVKYYMENAVELSVPLVVDMKIG  879
             + + ++   + + M+LQVHDE++++V   E+  +++LVK  ME AV+L+VPL VD   G
Sbjct  814  NLDKALQAGGFRAKMLLQVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTG  873

Query  880  PNWYDVQ  886
             +WY+ +
Sbjct  874  QSWYEAK  880

455) MMALV_07150 in NC_020913


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  537 bits (2025),  Expect = 2e-153, Method: Compositional matrix adjust.
 Identities = 368/891 (42%), Positives = 568/891 (64%), Gaps = 36/891 (4%)

Query  2    KGKVLLVDGFSILFRSFYAMPPNM---TAPDGTHTNAVYGFLSILNKEVEEESPDHLAVA  58
            K K+LL+DG S+ FR+F+A+  ++       G HTNA+YGF  +L+  +    P H+ VA
Sbjct  4    KNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVA  63

Query  59   FDLPSPTFRHKLYPEYKGTRKPAPSEFTEQIPVLRSLLDQMGIPVVSAEGWEADDVLGSL  118
            FD    TFR  +Y++YK+ R  +P EF EQ++ +R +L  +GI+    E  EADD++G+L
Sbjct  64   FDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTL  123

Query  119  AGQAEASG--YEVRILSGDRDLLQTVTDSTVVVIPKTKGGQTVYEHYSPEDVQETYGVTP  176
               AE +   ++V I+SGD+DL+Q   ++TVV I+K   G + +E+++P  + E  G+TP
Sbjct  124  DKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKK--GVAEFEEFTPAYLMEKMGLTP  181

Query  177  QAFIELKALMGDASDNVPGLPGVGEKTAQKILAQFGTIENAYAHVDELKPPKAAAAMRDG  236
            + FI+LKALMGD SDN+PG+  +GEKT+ K+L +FG++E  Y H+D +K +K    + ++
Sbjct  182  NQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIND  241

Query  237  YDTLLLSKELVTIRRDAPVT--FDEEAFR------MGNIYTPEAYDSFKRLGFKSMLGRF  288
             D  +LSK L TI   +P+T  +D+  +       ++++Y    +  +K+ G+ S + + 
Sbjct  242  RDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKK-GLASQMPQ-  299

Query  289  GDVAVRSPSERKRAAEA--GDPDSFLPYFEGKDIGVSAVFQDGAFYGACICSSDRSVFLP  346
              VAV S  E    +    +  D F  YFE     +   ++  A+ G     +++ ++ +
Sbjct  300  EPVAVISYQEVTNVSADLFSAEDIF--YFET----LRDNYHREAIIGFAWGHGEQ-IYAS  352

Query  347  RRLGEDLLRRNIAEAVSRSSSAATV--DAKGLLRWMRADVSPRMVDCVVAAYLLNPLKSD  404
              L+  LL  +    V + + A+     +K LL  +  ++ +   D  +A YLL+ +  +
Sbjct  353  TDLS--LLATDSFKQVFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDN  410

Query  405  WNCESVASGFLNESIPAREEVLGKSVNM-LTDPAAISDFALTEADVALRSAPLLLKSLED  463
             +  ++A  F + S+   + V GK+ +  + D   + +       V L S + +L  L  
Sbjct  411  -ELSTIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTA  469

Query  464  AGMLPLFRDVEMPLTYVLASMESNGICASKDKLKEYSDKLGVRIADLTAEIYREAGQEFN  523
               L L++++E+PL+ VLA ME +GI  ++  L++ +++  V I  LT EIY  AGQEFN
Sbjct  470  HEQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFN  529

Query  524  INSPKQMGIVLFEKM--GIQGAKRTKTGYSTAEDVLEKLAPDHPIVAHILEYRSCAKLKS  581
            INSPKQ+G +LFEKM   ++ +K+TKTGYSTA DVLE+LAP  PIVA IL+YR  +KL+S
Sbjct  530  INSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQS  589

Query  582  TYADALADYIRKDGRIHTSFNQTITATGRLSSSDPNLQNIPMKDDMGRRIRKCFHPA-EG  640
            TY  +L DYI  DG+IHT + Q +T TGRLSS DPNLQNIP++ + GR IRK F P+ E+
Sbjct  590  TYVIGLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHED  649

Query  641  CVFVDADYSQIELRVLAHMSGDENLINAYRQSKDIHRTTASQIFHV-PFEEVTDQMRRNA  699
             V++ +DYSQIELRVLAH+SGDE+LI A+ ++ DIH +TA ++F +    +VT + RRNA
Sbjct  650  AVLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNA  709

Query  700  KAVNFGIVYGISSFGLSQGLSISRKEADEFIDQYFRTYPRIKDFLDGLISSAKEKGYAES  759
            KAVNFGIVYGIS FGLS+ L+I+RK++  +ID YF  YP IK +++ ++  AK+KGY E+
Sbjct  710  KAVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVET  769

Query  760  LYGRRRPIPELNAANYIQRSFGERAAMNSPIQGTAADIIKMAMNRVMRRLSADVPDAKMV  819
            L+ RRR +P++N+ N+  RSF+ER+A+NSPIQG+AADI+K+AM  + + L A+   AKM+
Sbjct  770  LFKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKML  829

Query  820  LQIHDEILIECKEADADRVADILRTEMAAAADLKVELETDCHIGRDWYEAK  870
            LQ+HDEI++E  + +   +  +++  M AA DL V L  D   G+ WYEAK
Sbjct  830  LQVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

456) polA in NC_014614


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  536 bits (2021),  Expect = 3e-153, Method: Compositional matrix adjust.
 Identities = 384/891 (44%), Positives = 582/891 (66%), Gaps = 35/891 (3%)

Query  16   LILIDGNSLMNRAYYAL----PELMNKKGQHTNAIYGFANILFKIMDTYKPSHISVAFDL  71
            L+LIDG+S+  RA++AL      + N  G HTNAIYGF  +L  +M   +P+H+ VAFD 
Sbjct  7    LLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAFDA  66

Query  72   KAPTFRHKQYDAYKGNRKKMPDELREQVEPLKKMIDAFGINRIELEGYEADDLIGTVAKN  131
               TFR   Y  YK+ R K PDE+REQ   ++ M+ A+GI   ELE YEADD+IGT+ K 
Sbjct  67   GKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLDKM  126

Query  132  FEQDG--FEVYIITGDKDALQLVSDKIKVLFTKKGISELDEYDPDKMTEKYELTPQQFID  189
             E+    F+V I++GDKD +QL  ++  V ++KKG++E++E+ P  + EK  LTP+QFID
Sbjct  127  AERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQFID  186

Query  190  LKGLMGDQSDNIPGVAGIGEKTGIKLLKEYGSIENIYMNIDEISKS-VKAKLEAGYDMAF  248
            LK+LMGD+SDNIPGV+ IGEKTG+KLL E+GS+E IY +ID +  S +K +L  + D AF
Sbjct  187  LKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRDQAF  246

Query  249  LSKSLATIMVDIPLELKVDEFEKKDIDKNTLISLFSEFEFNSLIGKVGNDESGLIDKVQK  308
            LSK+LATI    P+ + +D++  ++ D  +L  ++ E +F  L         GL  ++ +
Sbjct  247  LSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQL-------KKGLASQMPQ  299

Query  309  EYLISNDIELLIDKATSL---KSLNLFSIAKSGLVSDKRLINLFVKIDEEFFNIEEKDVL  365
            E +     + + + ++ L     +  F   +     +  +I +    +E+++   +  +L
Sbjct  300  EPVAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREA-IIGFAWGHGEQIYASTDLSLL  358

Query  366  ---KLKDVFENPEIKKYGYNLKNDCLILKPYEINLTGLYFDIAIAEYLIDSTSSNYEIKD  422
                +K+VF++P I  Y++  K   ++L    I+L +  +D  +A+YL+ +   N E+  
Sbjct  359  ATDSFKQVFQKP-IATYDF--KRSKVLLSHLGIELVAPSYDARLANYLLSTVEDN-ELST  414

Query  423  IALKYNLGDVlsleellgkgkskkDFKDLSDAQIS-GYACSVLDIVDKGKEALITTIENY  481
            IA  +   D+   E+    GK+ K  + ++D ++        + ++  +K  ++  +   
Sbjct  415  IARIFT--DISLEEDDTVYGKGAK--RAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAH  470

Query  482  NMHNLFYEVEMPLVEILADMEYIGISADKEVLNELKQKFDIEIKTLEASIYEYAGENFNI  541
            +  +L+ ++E+PL ++LA ME  GI  ++  L+++ ++  + I +L   IY+ AG++FNI
Sbjct  471  EQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNI  530

Query  542  NSPKQLGHILFDKLGLP--AIKKTKTGYSTNAEVLEALSDKHPIIDKITLYRQYTKLQST  599
            NSPKQLG ILF+K+ LP    KKTKTGYST  +VLE L+   PI+ KI  YRQ TKLQST
Sbjct  531  NSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQST  590

Query  600  YVDGLLNIINPKTGRIHSSFNQTITTTGRISSTEPNMQNIPVRLEIGRELRKVFVAP-ED  658
            YV GL + I +  G+IH+ + Q +T TGR+SS +PN+QNIP+RLE GR +RK F ++ ED
Sbjct  591  YVIGLQDYILAD-GKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHED  649

Query  659  MYLVDADYSQIELRILAHIANDEGLIDAFSKGDDIHTITASEVFNVP-LDEVTKELRSAA  717
              L+ +DYSQIELR+LAHI+ DE LI AF+ G DIHT TA  VF +    +VT + R  A
Sbjct  650  AVLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNA  709

Query  718  KAVNFGIVYGISDFGLSNNLGISKQVAKEYIDNYFARYPYVKKYMEDIVEKAKNDGYVET  777
            KAVNFGIVYGISDFGLSNNLGI+++ +K YID YF RYP +K YME++V  AK+ GYVET
Sbjct  710  KAVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVET  769

Query  778  YIGRRRYIPELGSNNFIMKNLGKRLAMNTPIQGSAADVIKIAMVKVYARLKSEGLKSKLI  837
             + RRR +P++ S NF +++++ R A+N+PIQGSAAD++KIAM+++   L++ G+++K++
Sbjct  770  LFKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKML  829

Query  838  LQVHDELIIESPDSEKSYVADLLKEEMESAVDLNVKLTVDAKWGKSWYETK  888
            LQVHDE+++E P+ E + +  L+K+ ME+AVDL V L VD   G+SWYE+K
Sbjct  830  LQVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

457) Clopa_2063 in NC_021182


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  535 bits (2018),  Expect = 6e-153, Method: Compositional matrix adjust.
 Identities = 386/895 (44%), Positives = 593/895 (67%), Gaps = 45/895 (5%)

Query  2    ERLLILDSNSLMNRAFYA----IPALNNAEGLNTNAIYGFINMLFKMREELKPDYIVATF  57
            ++LL++D++S+  RAF+A    I  ++N  GL+TNAIYGF  ML  M   ++P  ++ +F
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  58   DKKAPTFRHKEYKDYKAGRKKMPPELAEQFPVVKELLEKLAINIFEIEGFEADDLIGTLA  117
            D    TFR   Y DYKAGR K P E+ EQF+ ++E+L  L+I  +E+E +EADD+IGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  118  SFSRDRGI--EVYIVTGDRDALQLAEDNVKIVINKKGMTEKEIYDKDRMLLDYGVTPKQF  175
              +    +  +V IV+GD+D +QL+++N  + I+KKG++E E +    ++   G+TP+QF
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  176  IDVKGLMGDSSDNIPGVPGIGEKTALKLIKEYDSVENVLMNIENISGKKIKENLMEYSEQ  235
            ID+K+LMGD SDNIPGV  IGEKT+LKL+ E++S+E +  +I+ +   K+KENL++  +Q
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRDQ  244

Query  236  AVFSKKLATIITNVPIEIDLESIKSKDNFDVKAVRKMFLKLEFKSLMNKIPDSEEEEAVI  295
            A +SK LATI T  PI I+L+ I  ++  DV ++ + +  ++F  L + ++    +E+V 
Sbjct  245  AFLSKTLATINTASPITIGLDDIVYNGP-DVASLSQFYDEMDFVQLKKGLASQMPQEPVA  303

Query  296  EVKADYEVLDTIEKLKKFTSSVKDAIYILFENENENVYSKSVIKKIYVNLQDKNYVIDYD  355
             +   Y+ +  +     F++   D +Y  FE   +N Y +  I  +     ++ Y     
Sbjct  304  VI--SYQEVTNVSA-DLFSAE--DIFY--FETLRDN-YHREAIIGFAWGHGEQIYASTDL  355

Query  356  KLFKADSEELKLVLKSVFENEEIDKIIHDAKIPYTILDKIGISLKGLIFDTKIAAYLIDP  415
             L+ +DS      +K VF++      +  +K+   +L  +GI L +  +D+++A YL+  
Sbjct  356  SLLATDS------FKQVFQKPIATYDFKRSKV---LLSHLGIELVAPSYDARLANYLLST  406

Query  416  AKSEYQLNGLIRDSLNIDIKDEDELL---RVKEVQYLKAIYEDLSAKIKLL---------  463
               + +L+ + R   +I + ++D +      + V     + E+L+ K+K+L         
Sbjct  407  VEDN-ELSTIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLD  465

Query  464  -----NMEELFYDVEEPLIEVLSSMEGRGFKVDRVKLNELGEQFSEKIQQTQEEIYSISG  518
                 +  +L+ ++E PL +VL+ ME  G+KV+R  L++++EQ    I+   +EIY ++G
Sbjct  466  KLTAHEQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAG  525

Query  519  EEFNISSPKQLGKILFEKLDLP--VIKKTKTGYSTNAEVLEKLRDKHPIIDKITYYRQLT  576
            +EFNI+SPKQLG ILFEK++LP  + KKTKTGYST  +VLE+L    PI+ KI  YRQ+T
Sbjct  526  QEFNINSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQIT  585

Query  577  KLYSTYVEGLKAVIDVDDKIHSSFNQTVTTTGRLSSTEPNLQNIPIKHEMGREIRKVFIP  636
            KL STYV GL+  I  D+KIH+ + Q +T TGRLSS +PNLQNIPI+ E GR IRK F P
Sbjct  586  KLQSTYVIGLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTP  645

Query  637  DSSECVILSGDYSQIELRVLAHIADDENLINAFKHHSDIHTKTASEVFNVP-IDQVTPLM  695
               + V+LS+DYSQIELRVLAHI++DE+LI AF++ +DIHT TA  VF +    +VT+  
Sbjct  646  SHEDAVLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTAND  705

Query  696  RSNAKAVNFGIVYGIGDFSLAQDLKITKSKAKEYIDTYFARYPNVKKYLEDIVVKAKEEL  755
            R NAKAVNFGIVYGI+DF+L+++L IT+ ++K YIDTYF RYP +K Y+E++V  AK+  
Sbjct  706  RRNAKAVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKG  765

Query  756  YVTTILNRRRYIPEIKARNKMVASFGERLAMNTPIQGSAADIIKLAMVKVYEKLNKEKLK  815
            YV T+++RRR +P+I++RN  V SF+ER A+N+PIQGSAADI+K+AM+++   L+   ++
Sbjct  766  YVETLFKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFR  825

Query  816  STIILQVHDELILNVYkdelekvkklvkdeMENAIELKVPLEVDINIGETWYEAK  870
            + ++LQVHDE++L+V +DEL  +KKLVKD ME A++L VPL VD + G++WYEAK
Sbjct  826  AKMLLQVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

458) polA in NC_017068


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  534 bits (2017),  Expect = 7e-153, Method: Compositional matrix adjust.
 Identities = 379/902 (43%), Positives = 587/902 (66%), Gaps = 59/902 (6%)

Query  2    NQRFVILDGSSLMYRAFYAL----PDLTDSQGHHTNAIFGFSNMLTKLLSELKPDKLVIA  57
            +++++++DGSS+ +RAF+AL      + +  G HTNAI+GF  ML  ++  ++P  +++A
Sbjct  4    KNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVA  63

Query  58   FDKGRKTFRTERYADYKGTRDKTPEELLAQIPLLHEFAAAFGISFIEKERYEADDIIGTL  117
            FD G+ TFRTE YADYK+ R KTP+E+  Q++ ++E  +A+GI++ E E+YEADDIIGTL
Sbjct  64   FDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTL  123

Query  118  ATKA--AGAGHDVLVVTGDKDALQLVRPNLKVLLTKKGITNIKEYDEAAFEEEYGFEPIK  175
               A  +    DV +V+GDKD +QL   N  V ++KKG++++ E+  A + E  G+ P +
Sbjct  124  DKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQ  183

Query  176  LIDYKGLMGDTSDNIPGVPNVGPKTAGKLLIAYGSLEGVYEHIDEVSGKKLKENLVNNQE  235
            +ID K+LMGD SDNIPGV ++G KT+ KLL  +GSLEG+YEHID     K+KENL+N+++
Sbjct  184  FIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRD  243

Query  236  QAVLSKELATIECNVP-DMELAWDSYDITPDHEKMRAFCDAYELKAVWKNFTKLYGEGDD  294
            QA LSK LATI+   P  + L    Y+  PD   +  F D  ++  + K ++        
Sbjct  244  QAFLSKTLATINTASPITIGLDDIVYN-GPDVASLSQFYDEMDFVQLKKGLASQ------  296

Query  295  NPVLEFFMPEAVAADLHYTRLQGQDLQRELTAADSL----AVSGIFAQEK--PFARVKAL  348
                   MP+   A + Y   +  ++  +L +A+ +    ++ + + +E    FA+  + 
Sbjct  297  -------MPQEPVAVISYQ--EVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGE  347

Query  349  LICTLPAQNMILVDADEDLALAKEICAQKDMTVYNLKA----YYQAGFTPADRYFDVELA  404
             I   ++ ++ L+ +D      K++  QK ++ Y++K       + G+      +D  LA
Sbjct  348  QIY--ASTDLSLLATDS----FKQVF-QKPIATYDFKRSKVLLSHLGIELVAPSYDARLA  400

Query  405  AYLLNPEASKYELERLAAEY--LPQEVKPAAFADEYEEAAWQAHVL-----ARLQPILNA  457
             YLL+    + EL  +A  +  ++ E   + ++     A  + +VL      +++ +L++
Sbjct  401  NYLLSTVEDN-ELSTIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDS  459

Query  458  K---LGEL----QLDKLYREIELPLVEVLAAIEQNGIYINRDELDKKGRELESRLESLQA  510
            K   L+ L    QLD LY++IELPL +VLA +E +GI +NR  L+  + +    +E+L  
Sbjct  460  KSQMLDKLTAHEQLD-LYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQ  518

Query  511  DIHLLAGMEFNINSPKQLGEVLFERLELP--PVKKTKTGYSTNAEVLEALRDKHPIVEQV  568
            +I  +AG EFNINSPKQLG +LFE+++LP    KKTKTGYST  +VLE L    PIV ++
Sbjct  519  EIYDMAGQEFNINSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKI  578

Query  569  LHFRTLSKLKSTYIDGLRDLIGKEGRIYTTFNQTVTATGRLSSSDPNLQNIPVRTEEGKA  628
            L++R ++KL+STY+ GL+D I  +G+I T + Q +T TGRLSS DPNLQNIP+R E+G+ 
Sbjct  579  LDYRQITKLQSTYVIGLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRL  638

Query  629  IRALFEPGDGYDCLLSADYSQIELRILAHASQDERFMDAFRQNQDIHARTASEVFNV-PL  687
            IR  F P++    LLS+DYSQIELR+LAH S DE+++ AF +  DIH+ TA  VF +   
Sbjct  639  IRKAFTPSHEDAVLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKA  698

Query  688  DEVTSQQRSHAKAVNFGIVYGISDFGLAKDLHIAKKDAKQYIDNYFARYTGVKKFIDDTV  747
             +VT+++R +AKAVNFGIVYGISDFGL+++L I++K++K YID YF RY G+K ++++ V
Sbjct  699  ADVTANDRRNAKAVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVV  758

Query  748  EKAHADGYVTTIFGRRRDLPAINSRNFMQRSLAERMAMNTPIQGAAADIIKLAMIAVYHK  807
              A   GYV T+F RRR+LP INSRNF  RS+AER A+N+PIQG+AADI+K+AMI +   
Sbjct  759  REAKDKGYVETLFKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKA  818

Query  808  LKEADVKSRILVQVHDELVLEVIDSEREQVEKILKEAMEQVTELSVPLLIDIHAGKNWAE  867
            L+ ++ ++++L+QVHDE+VLEV + E   + K++K++ME   +L+VPL +D  +G++W E
Sbjct  819  LQAGGFRAKMLLQVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYE  878

Query  868  AK  869
            AK
Sbjct  879  AK  880

459) polA in NC_021284


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  531 bits (2002),  Expect = 1e-151, Method: Compositional matrix adjust.
 Identities = 367/890 (42%), Positives = 588/890 (67%), Gaps = 38/890 (4%)

Query  2    NKILLIDGNSLIFRAFYATAYSGEMLKSLDGTPTNAVYAFANMLNKILKDNNYYSVVVAF  61
            NK+LLIDG+S+ FRAF+A     + +K+  G  TNA+Y+F  ML+ ++K      V+VAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  62   DKGKINFRHDLIADYKAGRSKTPEELVQQFPIVKEFLDSYQIPYLEKEGYEADDLLGCLA  121
            D GK  FR ++ ADYKAGR+KTP+E+ +QF+ ++E L +  I+Y E E YEADD++G L 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  122  KQAETQN--YYVDILSSDKDLFQLISDKTNILIPRQGDSA-DIFDKTALLNKWEVSPEQV  178
            K AE  +  + V I+S+DKDL+QL  ++T + I+++G +  + F  + L++K  ++P+Q 
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  179  PDLKGLMGDPSDNLKGIPGVGEKTAIKLIKEYQTIENIYQNIDDIKGS-LKNNLISHQAE  237
             DLK+LMGD SDN+ G+  +GEKT++KL+ E+ ++E IY++ID++K S +K+NLI+++ +
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRDQ  244

Query  238  ALLCKKVATILCD----LELGDFAFSKLEVNKEKLLDFYLKYNMNSYVTKLYNNSEPVKQ  293
            A+L K +ATI       + L+D+ ++  +V    L +FY   +       L   S+  ++
Sbjct  245  AFLSKTLATINTASPITIGLDDIVYNGPDVAS--LSQFYDEMDFVQLKKGL--ASQMPQE  300

Query  294  SLAV---KVITEWSEEWNEDGTTVFLELFDENYHLSELIGFGIVNSHGIFYFDYTSAKFD  350
            ++AV   + +T+ S +        ++E + +NYH   +IGF+  +++ I    Y+S+ + 
Sbjct  301  PVAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQI----YASTDL-  355

Query  351  TSFHAFLANENYQKF------TYNAKSLIVGLGRDNITINNISYDMMLAGYIYNSNTKNT  404
                ++LA +++++       TY+ K   V L++  I +   SYD  LA Y+ ++   N 
Sbjct  356  ----SLLATDSFKQVFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNE  411

Query  405  LDNYINLFAKKQILSDELFYGKGVKKTIPTDLNKLSYFIGEKANYIHTLREKIVSLLTSS  464
            L     +F+   +  D+  YGKG K+++P     L   ++ K + +   + +++  LT+ 
Sbjct  412  LSTIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEH-LARKVKVLLDSKSQMLDKLTAH  470

Query  465  NQYQLYYDIELPTTFALARMERAGVKVDQRELSKQTVRIEQIVNDLNREINTMANKEVNP  524
            +Q +LY +IELP +  LA+ME  G+KV++  L   + +   I++ L +EI  MA +E N 
Sbjct  471  EQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNI  530

Query  525  NSPKQLSELLYQDLQL-----KDHKKG-STAQEVLETIKLSHPIISKILDYRKYQKLYST  578
            NSPKQL+ +L++ +QL     K  K G STA +VLE +    PI++KILDYR+  KL ST
Sbjct  531  NSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQST  590

Query  579  YLKGMEKYLFQDGKVHTIYKQTLTATGRLSSVEPNMQNISIRDEVQKEVRKIFVVSSEDN  638
            Y+ G++ Y++ DGK+HT Y Q LT TGRLSSV+PN+QNI+IR E  + +RK F  S ED 
Sbjct  591  YVIGLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDA  650

Query  639  ILLSADYSQIELRILADMSKDDHMLAAFNAGEDIHTNTAMKIFNLKKE-EITSTIRRSAK  697
            +LLS+DYSQIELR+LA++S D+H++AAFN G DIHT+TAM++F + K  ++T+  RR+AK
Sbjct  651  VLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAK  710

Query  698  AVNFGIIYGISDFGLANDLNISVPEAKEIIQNYYQQFPTIKNFIDSQVEFCKNNGYVMTM  757
            AVNFGI+YGISDFGL+N+L I+  ++K  I+ Y++++P IK ++++ V   K++GYV T+
Sbjct  711  AVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETL  770

Query  758  FNRKRYVPEINDANYMQREFGKRIAMNMPIQGTAADIIKIALKNIDQELLRLKLRTKIIA  817
            F+R+R +P+IN  N+  R F+ R A+N PIQG+AADI+KIA+ N+D+ L    +R+K++ 
Sbjct  771  FKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLL  830

Query  818  QIHDELIFEVPKTELAQVKALVKDLMENSTKLSVKLTVDMVEGASWYQLK  867
            Q+HDE+++EVP+ EL+ +K LVKD ME +  L+V L VD   G SWY+ K
Sbjct  831  QVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

460) polA in NC_013199


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  531 bits (2003),  Expect = 7e-152, Method: Compositional matrix adjust.
 Identities = 338/651 (52%), Positives = 480/651 (74%), Gaps = 13/651 (1%)

Query  1    MTSQTKLLLIDGNSIAFRAFFALYNQLDRFTNQDGLHTNAIYAFNNMLEIVLKSVKPDAA  60
            M ++ KLLLIDG+S+AFRAFFALYNQ+DRF N+ GLHTNAIY+F+ ML+ ++K V+P   
Sbjct  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60

Query  61   LVAFDAGKTTFRTAKYADYKSGRAKTPSELLEQLPYIKELLDDMGIQHYELKDYEADDII  120
            LVAFDAGKTTFRT  YADYK+GRAKTP E+ EQ++YI+E+L  +GI  YEL +YEADDII
Sbjct  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120

Query  121  GTMAKRAD--DAGWQTTIVTGDRdltqlttdqttvqvtvKGVNELEAYTPEHVKEKLGIT  178
            GT+ K A+  +   + TIV+GD+DL QLT ++T V+++ KGV E+E +TP  + EK+G+T
Sbjct  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180

Query  179  PTQIIDLKGLMGDTSDNYPGVTKVGEKTALKLLKQYGSIENLYANIDAMKTSKMKENLIN  238
            P Q+IDLK+LMGD SDN PGVTK+GEKT+LKLL ++GS+E +Y +ID+ KTSKMKENLIN
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  239  DKDKAYLSKQLATIDRDAPVTIDLADVKYNGPDLAKLRDFYTKMNMNSLLKKIGGDVAK-  297
            D+D+A+LSK LATI+  +P+TI+L D+ YNGPD+A L +FY  M+   L K +++++++ 
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQE  300

Query  298  PSQPVHYSVLDDQSILALTKTTEPLTFEIEMLADNYHTAEQVGFFIGTKEETYVSTDVSL  357
            P   + Y  + + S   L  + + + FE   L DNYH    +GF  G  E+ Y STD+SL
Sbjct  301  PVAVISYQEVTNVSA-DLFSAEDIFYFET--LRDNYHREAIIGFAWGHGEQIYASTDLSL  357

Query  358  LTIPEVAKWLGDSNRDLTVFDGKRNIVAAHRLGLHLPDIAFDVLLASYLINPDENSNDLG  417
            L+     + +   ++ ++ +D KR+ V   +LG++L   ++D  LA+YL++  E+ N+L+
Sbjct  358  LATDSFKQVF---QKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVED-NELS  413

Query  418  KIAEDHDYHDLPRDEDVYGKGAKRQVPEDKLLFEQFARKSQALFALRPDLTEDLAKQEQT  477
             IA       L  D+ VYGKGAKR VP+  +L+E++ARK + L+  ++++ + L+ +EQ 
Sbjct  414  TIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQL  473

Query  478  DLFTDMEMPLARVLAEMEIQGITLNAQTLKDMGTEFSQSIKVLEEKIYGEAGVKFNLNSP  537
            DL+ ++E+PLA VLA MEI+GI +N  TL+DM+ +    I  L + IY+ AG  FN+NSP
Sbjct  474  DLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSP  533

Query  538  KQLGEVLFEKLNLP--VIKKTKTGYSTSVDVLNELKSASPIVQDILDYRGWAKLNSTYVV  595
            KQLG +LFEK++LP  + KKTKTGYST+VDVL+ L + +PIV  ILDYR  +KL+STYV+
Sbjct  534  KQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVI  593

Query  596  GLLKAQMPDHKIHTRYLQTLTQTGRLSSVDPNMQNIPAR-DEGKIIRKPLS  645
            GL    ++D KIHTRY+Q LTQTGRLSSVDPN+QNIP R ++G++IRK+++
Sbjct  594  GLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFT  644

461) Halha_0427 in NC_019978


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  530 bits (2001),  Expect = 1e-151, Method: Compositional matrix adjust.
 Identities = 376/885 (43%), Positives = 578/885 (66%), Gaps = 43/885 (4%)

Query  2    SKQRLYLLDGNSLVYRAFYAL---PDTLTTSDGTVTNAVFGFTKMLLSLIDNQAPDLIGI  58
            +K++L L+DG+S+ +RAF+AL    D +    G  TNA++GF  ML  ++    P  + +
Sbjct  3    NKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLV  62

Query  59   AFDAQGATFRHEEYEEYKANRKETPDKLKHQFDLVKEVVDALEIPRFEVESLEADDLIGT  118
            AFDA  +TFR E Y +YKA R  TPD +++QF  ++E++ AL I+ +E+E  EADD+IGT
Sbjct  63   AFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGT  122

Query  119  LAIEAEKED--YKVTIVTGDRDALQLISDNIEIMYTKRGISNIIRYDVDKFREDYELDPE  176
            L   AE+ +  + VTIV+GD+D +QL  +N  +  +K+G++++  +    + E   L P+
Sbjct  123  LDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPN  182

Query  177  QLVDKKALMGDKSDNIPGVDGIGDKTSTKLLKEFGGLEEVLDNIDQVGGKKRKQMLREQG  236
            Q++D KALMGDKSDNIPGV  IG+KT+ KLL EFG+LE + ++ID     K K+ L ++ 
Sbjct  183  QFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDR  242

Query  237  ARAKLSKRLATIKVDCPLEINFDKLVLADLEDIDQAYDLFNRLEFTSLISYLGGHKGLEK  296
             +A LSK LATI+   P+ I +D +V  +  D+    ++++ ++F  L   L+++   E 
Sbjct  243  DQAFLSKTLATINTASPITIGLDDIVYNG-PDVASLSQFYDEMDFVQLKKGLASQMPQEP  301

Query  297  V---DYQEVNELEELQSLKLPSTIAIKLNLNGPRLKQTLEGIIIATLEQVYYINLAEKEL  353
            V    YQEV ++     L  +  I     L +   ++++ G+  +  EQ+Y    A  +L
Sbjct  302  VAVISYQEVTNVSA--DLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQIY----ASTDL  355

Query  354  ITYLEDT---LVDKKLLMYQAKGQLRYLLQQGIEEFNLSFDPLLAAYLLQPSEDAIDLAG  410
                 D+   + +K +  Y+ K     L + GIE    S+D+ LA YLL   ED  +L+ 
Sbjct  356  SLLATDSFKQVFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDN-ELST  414

Query  411  IIEKY----LQQAEP--------EVTG----IKLLAVRTNIlfklqikleeelkendlle  454
            I   +    L++ +          V +    +  LA + ++L+  + ++ + L  ++ L+
Sbjct  415  IARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLD  474

Query  455  lFQDMELPLVRILAQLELNGIKVSQEQLENLFTELSTKISKLKKEICNLAGEEFNINSPQ  514
            L+Q++ELPL  +LA++E++GIKV++  L+++  +    I  L +EI ++AG+EFNINSP+
Sbjct  475  LYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPK  534

Query  515  QLGTILFDKLDLPV-IKKTSTGNYSTSAKVLEKLEGNHEIIPLISEYRSLTKLKSTYVDP  573
            QLG+ILF+K++LP+ + K +   YST+  VLE+L     I++ I +YR +TKL+STYV  
Sbjct  535  QLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIG  594

Query  574  LESYINEKTGRIHTNFKQQVTATGRLSSREPNLQNIPIRTEEGRKIRQVFV-AQEGYKLV  632
            L+ YI    G+IHT + Q++T TGRLSS +PNLQNIPIR E+GR IR+ F  ++E+  L+
Sbjct  595  LQDYILAD-GKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLL  653

Query  633  AADYSQVELRVLAHISQDERLKKAYQQGLDIHTQTAKELFGIS-----TKQTRRKAKAVN  687
            ++DYSQ+ELRVLAHIS DE+L  A+++G DIHT TA  +FGI      T + RR+AKAVN
Sbjct  654  SSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVN  713

Query  688  FGIAYGISDWGLADRLKINKREAKEYIDLYFSRYPKVKEYIDDKIRQAKKQGYVTTIFDR  747
            FGI YGISD GL++ L I ++++K YID YF RYP +K Y+++ +R+AK +GYV T+F R
Sbjct  714  FGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKR  773

Query  748  KRYLPEINSRNYHKRQFAERTAINTPIQGSAADIMKLAMLDVAKALEKEELASDILLQVH  807
            +R LP+INSRN++ R FAERTAIN+PIQGSAADI+K+AM+++ KAL+   + + +LLQVH
Sbjct  774  RRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVH  833

Query  808  DELVLEVPKDEVKKVAKLVKKRMEDTVNLDVPLEVDVKVGDNWNE  852
            DE+VLEVP+DE+  + KLVK  ME +V+L VPL VD   G++W E
Sbjct  834  DEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYE  878

462) Cbei_0801 in NC_009617


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  529 bits (1998),  Expect = 2e-151, Method: Compositional matrix adjust.
 Identities = 379/907 (42%), Positives = 599/907 (67%), Gaps = 72/907 (7%)

Query  2    KKLLILDSNSLMNRAFYAL----PPLTNSDGINTNAIYGFINMLLKMKDEINPDSIIATF  57
            +KLL++D++S+  RAF+AL      + N  G++TNAIYGF  ML  M   + P  ++ +F
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  58   DLKAPTFRHKEYSEYKAGRNKMPPELAEQFPIIKELFKLMGIKIFEVEGFEADDLIGTVS  117
            D    TFR   Y++YKAGR K P E+ EQF+ I+E++  +GI  +E+E +EADD+IGT+ 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  118  KFAEDNNA--EVFVVTGDRDALQLASEKTKIIITKKGVSETAVYDKESFMDEFEVTPEQF  175
            K AE  +   +V +V+GD+D +QL+ E+T + I+KKGV+E   +    +M+   +TP+QF
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  176  IDVKGLMGDKSDNIPGVPGVGEKTAFKLIKEYGSVEKVIKNIDKISGKKLKENLENNVEQ  235
            ID+K+LMGDKSDNIPGV  +GEKT++KL+ E+GS+E +  +ID +   K+KENL N+ +Q
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRDQ  244

Query  236  AIFSKKLATIMREVPIELNLEDISSNNKENILEIKKMLIKLE----MKSILSKFKDDTVH  291
            A++SK LATI    PI + L+DI  N  + +  + +    ++     K++ S+  ++ V 
Sbjct  245  AFLSKTLATINTASPITIGLDDIVYNGPD-VASLSQFYDEMDFVQLKKGLASQMPQEPVA  303

Query  292  EESNIEVRNITTIEDMKELFSEMRNRIYIDYTLTDASRYSKLKLEYLILGEENKGTIIDF  351
              S  EV N+++     +LFS   + I+  Y       +  L+ +Y      ++ +II+F
Sbjct  304  VISYQEVTNVSA-----DLFSA--EDIF--Y-------FETLRDNY------HREAIIGF  341

Query  352  KDISSKDSEEALKVLK-NLMEDDNVKKVIHDGKNFVTF--------LNKNQIEIKGFDFD  402
               +  ++E+       +L+  D+ K+V++  K + T+        L+   IE+ +  +D
Sbjct  342  ---AWGHGEQIYASTDLSLLATDSFKQVFQ--KPIATYDFKRSKVLLSHLGIELVAPSYD  396

Query  403  TAIAAYLIDSSKSKYEILELVNHYIGDNPNSEGSNI-----------KAILCSYLP----  447
            + +A YL+ +     + L  + + + D +  E+  +           K +L   L+    
Sbjct  397  ARLANYLLSTVED--NELSTIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVK  454

Query  448  MVYEKLKENLHK----ENMDQLYYEVEHPLIYVLSSMESIGFNINQGMLDELQTKFKKEI  503
            ++ +   + L+K    E++D LY ++E PL  VL+ ME  G+++N++ L+++  + K  I
Sbjct  455  VLLDSKSQMLDKLTAHEQLD-LYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVII  513

Query  504  DKTQKEIYELADEEFNISSPKQLGKILFEKLDLPV--IKKTKTGYSTNQEVLEKLMNKHD  561
            +   +EIY++A++EFNI+SPKQLG ILFEK++LP+   KKTKTGYST  +VLE+L     
Sbjct  514  EALTQEIYDMAGQEFNINSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAP  573

Query  562  IIPKIMYYRQITKINSTYVEGLKNVVDEDGRIHSNFNQTVTTTGRLSSTEPNLQNIPIKY  621
            I++KI+ YRQITK++STYV GL++ +  DG+IH+ + Q +T TGRLSS +PNLQNIPI+ 
Sbjct  574  IVAKILDYRQITKLQSTYVIGLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRL  633

Query  622  EMGREIRKVFIPMEETDILVSCDYSQIELRVLAHIAGDENMIDAFEHHSDIHTKTASEVF  681
            E GR IRK F P +E  +L+S DYSQIELRVLAHI+GDE++I AF++ +DIHT TA  VF
Sbjct  634  EQGRLIRKAFTPSHEDAVLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVF  693

Query  682  KVP-IGEVTSLMRSRAKAVNFGIVYGISAFSLAEDLKITKKEAEEYMSIYLERYPKIKEY  740
             +   ++VT+  R  AKAVNFGIVYGIS F+L+++L IT+K++  Y+  Y+ERYP IK Y
Sbjct  694  GIDKAADVTANDRRNAKAVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAY  753

Query  741  LENVVDEAKEKGYVLTILNRRRFIPEIKSSNKIVKALGDRLAMNAPIQGSAADIIKLAMV  800
            +ENVV EAK+KGYV T+++RRR +P+I+S N  V+++++R A+N+PIQGSAADI+K+AM+
Sbjct  754  MENVVREAKDKGYVETLFKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMI  813

Query  801  NVYNKLNEKELKSELILQVHDELILNVKKDEFEEVKNLVAYEMENAIKLKVALDVDVNFG  860
            N+ + L+   +++ ++LQVHDE++L+V +DE+  +K+LV   ME A+ L V+L VD + G
Sbjct  814  NLDKALQAGGFRAKMLLQVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTG  873

Query  861  DTWYDAK  867
            ++WY+AK
Sbjct  874  QSWYEAK  880

463) HMPREF0389_00606 in NC_016630


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  528 bits (1991),  Expect = 8e-151, Method: Compositional matrix adjust.
 Identities = 377/888 (43%), Positives = 586/888 (66%), Gaps = 29/888 (3%)

Query  2    KRLFLIDGNSLINRAYYAL----PPLMTKDGLYTNAIYGFLMMFYKAMDEYAPDYVSVAF  57
            ++L+LIDG+S+  RA++AL      +    GL TNAIYGF +M+   M    P  V VAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  58   DLKGPTFRHKEYKDYKGTRKGMPPELAMQIQPLKELLDTMGVHRAEIEGFEADDIIGTLS  117
            D    TFR   Y DYK+ R   P E+  Q+  ++E+L ++G+   E+E +EADDIIGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  118  KIGE--DENLEVFILTGDRDALQLASKTTKILFTKKGISDLEVYDEDKVKERYELTPKQF  175
            K++E  +  ++V I++GD+D +QL+   T + ++KKG++++E +    + E+  LTP+QF
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  176  IDLKGLMGDSSDNIPGVAGIGEKTGIKLLKEYDSIENLILHIDELKGA-VKTKMEAGYES  234
            IDLK+LMGD SDNIPGV+ IGEKTG+KLL E++S+E +  HID +K + +K ++  + + 
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRDQ  244

Query  235  AVMSKRLATIVRVIPVEFSLDELLYEKKSGEQLRSLFMKYGFTSLMSKLEYKEEETSTTD  294
            A +SK LATI    P+ ++LD+++Y+      L  ++   +F  L   L  +  + + + 
Sbjct  245  AFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEPVAV  304

Query  295  I---NISYEIEELLQQNPTEIGLIAAIEDGNILTKRIVRLYLLADSITYAVEEENI---P  348
            I   +++    +L+  ++ +I  + ++ D N     I+ +    +   YA  + ++    
Sbjct  305  ISYQEVTNVSADLF--SAEDIFYFETLRD-NYHREAIIGFAWGHGEQIYASTDLSLLATD  361

Query  349  KLKELLERENVFIYGNNLKREYTALKPYGITLPKISFDSQLAQYILNPSEVEQEPEKIGI  408
             +K+++++  +  Y  ++KR    L   GI L   S+D++LA+Y+L+  E ++E   I+ 
Sbjct  362  SFKQVFQK-PIATY--DFKRSKVLLSHLGIELVAPSYDARLANYLLSTVE-DNELSTIAR  417

Query  409  KYGMPIVSPNLEDLLGKGKKRMSFSMANRVQMDEYFAKILAIISHCKTKMLDMIQEEDTK  468
             +    +  + + + GKG KR   +++++  + E +A+ + ++ + K++MLD +  ++  
Sbjct  418  IFTDISLEED-DTVYGKGAKR---AVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQL  473

Query  469  FLFEKIELPLMKVLGEMEYLGIAVNEDVLCELEQEFAKLIVQYEQEIYDLAGEEFNINSP  528
             L+++IELPL +VL+ ME  GI VN   L ++ ++   +I    QEIYD+AG+EFNINSP
Sbjct  474  DLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSP  533

Query  529  KQLGVVLFEKLQLP--VIKKTKTGYSTGAEILEKLYDKHPIISKILSYRQVSKLQSTYVI  586
            KQLG +LFEK+QLP  + KKTKTGYST+ ++LE+L    PI++KIL YRQ++KLQSTYVI
Sbjct  534  KQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVI  593

Query  587  GLLSLINPTSKRIHSTFNQTLTTTGRISSLEPNLQNIPVRTEMGRELRKVFV-AKEGYVL  645
            GL   I + +K IH+ + Q LT TGR+SS++PNLQNIP+R E GR +RK F  + E+ VL
Sbjct  594  GLQDYILADGK-IHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVL  652

Query  646  VDADYSQIELRVLAHMAQEKKMIEGFHGSMDIHTKTASEVFSVP-VEEVTKELRSAAKAV  704
            + +DYSQIELRVLAH++ +  +I +F+ + DIHT TA  VF++    +VT + R  AKAV
Sbjct  653  LSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAV  712

Query  705  NFGIVYGISDFGLSNNLNITKKQAKEYIDLYFARYPGIKTYMDTIVKEVEELGYSTTLCG  764
            NFGIVYGISDFGLSNNL IT+KQ+K YID YF RYPGIK+YM+ +V+E  + GY  TL  
Sbjct  713  NFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFK  772

Query  765  RRRYIPEIKSSNFIVKNMGKRLAMNTPIQGSAADIIKIAMNRVFEWLKTEKIDAELVLQV  824
            RRR +P+I+S NF V++ + R A+N+PIQGSAADI+KIAM  +   L++  + A ++LQV
Sbjct  773  RRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQV  832

Query  825  HDELLLEVREDDAKYVRDKVIELMEGAWSMDVPLKVDATIGDSWYETK  872
            HDE++LEV +D+   ++  V + ME+A  + VPL VD + G+SWYE+K
Sbjct  833  HDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

464) polA in NC_021280


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  525 bits (1980),  Expect = 6e-150, Method: Compositional matrix adjust.
 Identities = 363/891 (41%), Positives = 595/891 (67%), Gaps = 40/891 (4%)

Query  2    NKILLIDGNSLIFRAFYATAYSGEMLKSLDGTPTNAVYAFANMLNKILKDNNYYSVVVAF  61
            NK+LLIDG+S+ FRAF+A     + +K+  G  TNA+Y+F  ML+ ++K      V+VAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  62   DKGKVNFRHDLITDYKAGRSKAPEELVQQFPIVKEFLDSYQIPYLEKEGYEADDLLGCLA  121
            D GK  FR ++ +DYKAGR+K+P+E+ +QF+ ++E L +  I+Y E E YEADD++G L 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  122  KQAEAQN--YYVDILSSDKDLFQLITDKTNILIPRQGDSA-DIFDKTALLNKWEVSPEQV  178
            K AE  +  + V I+S+DKDL+QL  ++T + I+++G +  + F  + L++K  ++P+Q 
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  179  PDLKGLMGDPSDNLKGIPGVGGKTAIKLIKEYQTIENIYQNIDNIK-GNLKNNLISHQDE  237
             DLK+LMGD SDN+ G+  +G KT++KL+ E+ ++E IY++ID +K +++K+NLI+++D+
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRDQ  244

Query  238  ALLCKKVATILCD----LDLGDFAFSKLEVNKEKLLDFY--LKYN--MNSYVTKLYNNNE  289
            A+L K +ATI       ++L+D+ ++  +V    L +FY  + +    ++  +++   +E
Sbjct  245  AFLSKTLATINTASPITIGLDDIVYNGPDVAS--LSQFYDEMDFVQLKKGLASQM--PQE  300

Query  290  PVKQSLEVKVITEWNEQWNEDGTTVFLELFDENYHLSELIGFGIVNSHGIFYFDYTSAKF  349
            PV   +  + +T+ + +        ++E + +NYH   +IGF+  +++ I    Y+S+ +
Sbjct  301  PV-AVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWGHGEQI----YASTDL  355

Query  350  DTSFHAFLANENYQKF------TYNAKSLIVGLGRDNITINNISYDMMLAGYIYNSNTRN  403
                 ++LA +++++       TY+ K   V L++  I +   SYD  LA Y+ ++   N
Sbjct  356  -----SLLATDSFKQVFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDN  410

Query  404  TLDNYINLFAKKQILSDELFYGKGVKKTIPTDLNKLSYFIGEKANYIHMLREKIVTLLTN  463
             L     +F+   +  D+  YGKG K+++P D + L   ++ K + +   + +++  LT 
Sbjct  411  ELSTIARIFTDISLEEDDTVYGKGAKRAVP-DKDVLLEHLARKVKVLLDSKSQMLDKLTA  469

Query  464  NNQYQLYYDIELPTTFALARMERAGVKVDQQELSKQTVRIEQIVNDLNREINTIANKEVN  523
            ++Q +LY +IELP +  LA+ME  G+KV++  L   + +   I++ L +EI  +A +E N
Sbjct  470  HEQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFN  529

Query  524  PNSPKQLSELLYQDLQL-----KDYKKG-STAQEVLETIKLSHPIISKILDYRKYQKLYS  577
             NSPKQL+ +L++ +QL     K  K G STA +VLE +    PI++KILDYR+  KL S
Sbjct  530  INSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQS  589

Query  578  TYLKGMEKYLFQDGKVHTIYKQTLTVTGRLSSVEPNMQNISIRDEIQKEVRKIFVVSSED  637
            TY+ G++ Y++ DGK+HT Y Q LT TGRLSSV+PN+QNI+IR E  + +RK F  S ED
Sbjct  590  TYVIGLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHED  649

Query  638  NILLSADYSQIELRILADMSKDDHMLAAFNAGEDIHTNTAMKIFNL-KRAEITPAIRRSA  696
             +LLS+DYSQIELR+LA++S D+H++AAFN G DIHT+TAM++F + K A++T+  RR+A
Sbjct  650  AVLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNA  709

Query  697  KAVNFGIIYGISDFGLANDLNISVPQAKEIIQNYYQQFPTIKNFIDSQVEFCKNNGYVVT  756
            KAVNFGI+YGISDFGL+N+L I+  Q+K  I+ Y++++P IK ++++ V   K++GYV T
Sbjct  710  KAVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVET  769

Query  757  MFNRKRYVPEINDANYMQREFGKRIAMNMPIQGTAADIIKIALKNIDQELLRLKLKTKII  816
            +F+R+R +P+IN  N+  R F+ R A+N PIQG+AADI+KIA+ N+D+ L    +++K++
Sbjct  770  LFKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKML  829

Query  817  AQIHDELIFEIPKTELTQVKALVKDLMENSTKLSVKLTVDMAEGTSWYQLK  867
             Q+HDE+++E+P+ ELT +K LVKD ME +  L+V L VD + G SWY+ K
Sbjct  830  LQVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

465) polA in NC_003030


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  525 bits (1979),  Expect = 7e-150, Method: Compositional matrix adjust.
 Identities = 387/913 (43%), Positives = 601/913 (66%), Gaps = 80/913 (8%)

Query  2    ERLLVLDGNSLMNRAFYAL----PELTNAEGLHTNGIYGFMTMLIKMRDEIKPDYIVTTF  57
            ++LL++DG+S+  RAF+AL      + N  GLHTN+IYGF  ML  M   ++P  ++ +F
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  58   DRKAPTFRHKEYEDYKAGRKKMPPELSEQFPVLKELLEKLAINIFEIDGFEADDLIGTLA  117
            D    TFR   Y DYKAGR K P E+ EQF+ ++E+L  L+I  +E++ +EADD+IGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  118  CFAKEKGI--EVYIVTGDKDALQLADDNVKVVINKKGMTEKEIYDKNRMIEEFGVTPVQF  175
              A    +  +V IV+GDKD +QL+D+N  V I+KKG++E E +    ++E  G+TP QF
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  176  IDVKGLMGDNSDNIPGVPGIGPKTAFKLIQEYGSVENVLDNIQNIKGKKIKENLENYAEQ  235
            ID+K+LMGD+SDNIPGV  IG KT++KL++E+GS+E + ++I+ +K  K+KENL N  +Q
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRDQ  244

Query  236  AVFSKKLATIMTNVPIEIDIEEIRSKESFDVEGARHLLRRLQF----KSIIEKIPSLNVE  291
            A +SK LATI T  PI I++++I  + + DV +  ++   ++F    K++  ++P   V 
Sbjct  245  AFLSKTLATINTASPITIGLDDIVYNGP-DVASLSQFYDEMDFVQLKKGLASQMPQEPVA  303

Query  292  AEKSDFVVEYNLIDEFPKFHELFSA--------IKDT---EIYMSYSIGNGELYSKIYID  340
                  V+ Y+ + + +   +LFSA        ++D    E  ++++ G+GE   +IY  
Sbjct  304  ------VISYQEVTNVSA--DLFSAEDIFYFETLRDNYHREAIIGFAWGHGE---QIYAS  352

Query  341  TIFMKVEEKTYIVDLKKIIEQNREDVLKDLKEF-FENKKIAKIIHDSKNMYTVLMKNGIK  399
            T +  +   ++    K++++       K +  + F   K+            +L   GI 
Sbjct  353  TDLSLLATDSF----KQVFQ-------KPIATYDFKRSKV------------LLSHLGIE  389

Query  400  IENLAFDTAIAEYLINPSKKEYNLKDAAEEMLLLDLTGEDN--------DIKIKEVYVMD  451
            +   ++D+ +A+YL++    + +L   A     + L  +D          +  K+V +++
Sbjct  390  LVAPSYDARLANYLLSTVEDN-ELSTIARIFTDISLEEDDTVYGKGAKRAVPDKDV-LLE  447

Query  452  KIYNKLK----------DKIKEYDMDELYYKVELPLIEVLSSMESEGFKVEKNKLQQIGD  501
             +  K+K          DK+   +  +LY ++ELPL +VL+ ME EG+KV++  LQ++++
Sbjct  448  HLARKVKVLLDSKSQMLDKLTAHEQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAE  507

Query  502  KFTVEIAKVKDEIYNMAGEEFNISSPKQLGKILFEKLDLPV--IKKTKTGYSTNAEVLEK  559
            +  V I  + +EIY+MAG+EFNI+SPKQLG ILFEK++LP+   KKTKTGYST  +VLE+
Sbjct  508  QNKVIIEALTQEIYDMAGQEFNINSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLER  567

Query  560  LMDKHPIIEKVVYYRQLTKLYSTYVEGLKPVIDVDEKIHSSFNQTVTTTGRLSSTEPNLQ  619
            L    PI+ K++ YRQ+TKL STYV GL+  I  D KIH+ + Q +T TGRLSS +PNLQ
Sbjct  568  LAPIAPIVAKILDYRQITKLQSTYVIGLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQ  627

Query  620  NIPIKNEMGREIRKVFVPENDNCIILSADYSQIELRVLAHIADDENLINAFKHHSDIHTK  679
            NIPI+ E GR IRK F P +++ ++LS+DYSQIELRVLAHI++DE+LI AF++ +DIHT 
Sbjct  628  NIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTS  687

Query  680  TASEVFRVP-IEEVTSRMRSNAKAVNFGIVYGISDFSLAQDIKVSKKEAKEYIDTYFERY  738
            TA  VF +    +VT+  R NAKAVNFGIVYGISDF+L++++ +++K++K YIDTYFERY
Sbjct  688  TAMRVFGIDKAADVTANDRRNAKAVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERY  747

Query  739  PNVKKYLEDIVVTAKKNMYVNTIMNRRRIIPEIASSNKIVKGFGERLAMNTPIQGSAADL  798
            P +K Y+E++V  AK + YV+T+ +RRR +P+I S N  V++F+ER A+N+PIQGSAAD+
Sbjct  748  PGIKAYMENVVREAKDKGYVETLFKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADI  807

Query  799  IKLSMVNVYSKIKQLKLKSRLILQVHDELILNVHkdelekvkelvklemeevmelkvple  858
            +K++M+N+   ++   ++++++LQVHDE++L+V +DEL  +K LVK  ME  ++L VPL 
Sbjct  808  LKIAMINLDKALQAGGFRAKMLLQVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLC  867

Query  859  vDIESGNTWYEAK  871
            VD  +G++WYEAK
Sbjct  868  VDESTGQSWYEAK  880

466) polA in NC_015687


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  525 bits (1979),  Expect = 7e-150, Method: Compositional matrix adjust.
 Identities = 387/913 (43%), Positives = 601/913 (66%), Gaps = 80/913 (8%)

Query  2    ERLLVLDGNSLMNRAFYAL----PELTNAEGLHTNGIYGFMTMLIKMRDEIKPDYIVTTF  57
            ++LL++DG+S+  RAF+AL      + N  GLHTN+IYGF  ML  M   ++P  ++ +F
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  58   DRKAPTFRHKEYEDYKAGRKKMPPELSEQFPVLKELLEKLAINIFEIDGFEADDLIGTLA  117
            D    TFR   Y DYKAGR K P E+ EQF+ ++E+L  L+I  +E++ +EADD+IGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  118  CFAKEKGI--EVYIVTGDKDALQLADDNVKVVINKKGMTEKEIYDKNRMIEEFGVTPVQF  175
              A    +  +V IV+GDKD +QL+D+N  V I+KKG++E E +    ++E  G+TP QF
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  176  IDVKGLMGDNSDNIPGVPGIGPKTAFKLIQEYGSVENVLDNIQNIKGKKIKENLENYAEQ  235
            ID+K+LMGD+SDNIPGV  IG KT++KL++E+GS+E + ++I+ +K  K+KENL N  +Q
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRDQ  244

Query  236  AVFSKKLATIMTNVPIEIDIEEIRSKESFDVEGARHLLRRLQF----KSIIEKIPSLNVE  291
            A +SK LATI T  PI I++++I  + + DV +  ++   ++F    K++  ++P   V 
Sbjct  245  AFLSKTLATINTASPITIGLDDIVYNGP-DVASLSQFYDEMDFVQLKKGLASQMPQEPVA  303

Query  292  AEKSDFVVEYNLIDEFPKFHELFSA--------IKDT---EIYMSYSIGNGELYSKIYID  340
                  V+ Y+ + + +   +LFSA        ++D    E  ++++ G+GE   +IY  
Sbjct  304  ------VISYQEVTNVSA--DLFSAEDIFYFETLRDNYHREAIIGFAWGHGE---QIYAS  352

Query  341  TIFMKVEEKTYIVDLKKIIEQNREDVLKDLKEF-FENKKIAKIIHDSKNMYTVLMKNGIK  399
            T +  +   ++    K++++       K +  + F   K+            +L   GI 
Sbjct  353  TDLSLLATDSF----KQVFQ-------KPIATYDFKRSKV------------LLSHLGIE  389

Query  400  IENLAFDTAIAEYLINPSKKEYNLKDAAEEMLLLDLTGEDN--------DIKIKEVYVMD  451
            +   ++D+ +A+YL++    + +L   A     + L  +D          +  K+V +++
Sbjct  390  LVAPSYDARLANYLLSTVEDN-ELSTIARIFTDISLEEDDTVYGKGAKRAVPDKDV-LLE  447

Query  452  KIYNKLK----------DKIKEYDMDELYYKVELPLIEVLSSMESEGFKVEKNKLQQIGD  501
             +  K+K          DK+   +  +LY ++ELPL +VL+ ME EG+KV++  LQ++++
Sbjct  448  HLARKVKVLLDSKSQMLDKLTAHEQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAE  507

Query  502  KFTVEIAKVKDEIYNMAGEEFNISSPKQLGKILFEKLDLPV--IKKTKTGYSTNAEVLEK  559
            +  V I  + +EIY+MAG+EFNI+SPKQLG ILFEK++LP+   KKTKTGYST  +VLE+
Sbjct  508  QNKVIIEALTQEIYDMAGQEFNINSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLER  567

Query  560  LMDKHPIIEKVVYYRQLTKLYSTYVEGLKPVIDVDEKIHSSFNQTVTTTGRLSSTEPNLQ  619
            L    PI+ K++ YRQ+TKL STYV GL+  I  D KIH+ + Q +T TGRLSS +PNLQ
Sbjct  568  LAPIAPIVAKILDYRQITKLQSTYVIGLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQ  627

Query  620  NIPIKNEMGREIRKVFVPENDNCIILSADYSQIELRVLAHIADDENLINAFKHHSDIHTK  679
            NIPI+ E GR IRK F P +++ ++LS+DYSQIELRVLAHI++DE+LI AF++ +DIHT 
Sbjct  628  NIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTS  687

Query  680  TASEVFRVP-IEEVTSRMRSNAKAVNFGIVYGISDFSLAQDIKVSKKEAKEYIDTYFERY  738
            TA  VF +    +VT+  R NAKAVNFGIVYGISDF+L++++ +++K++K YIDTYFERY
Sbjct  688  TAMRVFGIDKAADVTANDRRNAKAVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERY  747

Query  739  PNVKKYLEDIVVTAKKNMYVNTIMNRRRIIPEIASSNKIVKGFGERLAMNTPIQGSAADL  798
            P +K Y+E++V  AK + YV+T+ +RRR +P+I S N  V++F+ER A+N+PIQGSAAD+
Sbjct  748  PGIKAYMENVVREAKDKGYVETLFKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADI  807

Query  799  IKLSMVNVYSKIKQLKLKSRLILQVHDELILNVHkdelekvkelvklemeevmelkvple  858
            +K++M+N+   ++   ++++++LQVHDE++L+V +DEL  +K LVK  ME  ++L VPL 
Sbjct  808  LKIAMINLDKALQAGGFRAKMLLQVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLC  867

Query  859  vDIESGNTWYEAK  871
            VD  +G++WYEAK
Sbjct  868  VDESTGQSWYEAK  880

467) polA in NC_017295


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  525 bits (1979),  Expect = 7e-150, Method: Compositional matrix adjust.
 Identities = 387/913 (43%), Positives = 601/913 (66%), Gaps = 80/913 (8%)

Query  2    ERLLVLDGNSLMNRAFYAL----PELTNAEGLHTNGIYGFMTMLIKMRDEIKPDYIVTTF  57
            ++LL++DG+S+  RAF+AL      + N  GLHTN+IYGF  ML  M   ++P  ++ +F
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  58   DRKAPTFRHKEYEDYKAGRKKMPPELSEQFPVLKELLEKLAINIFEIDGFEADDLIGTLA  117
            D    TFR   Y DYKAGR K P E+ EQF+ ++E+L  L+I  +E++ +EADD+IGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  118  CFAKEKGI--EVYIVTGDKDALQLADDNVKVVINKKGMTEKEIYDKNRMIEEFGVTPVQF  175
              A    +  +V IV+GDKD +QL+D+N  V I+KKG++E E +    ++E  G+TP QF
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  176  IDVKGLMGDNSDNIPGVPGIGPKTAFKLIQEYGSVENVLDNIQNIKGKKIKENLENYAEQ  235
            ID+K+LMGD+SDNIPGV  IG KT++KL++E+GS+E + ++I+ +K  K+KENL N  +Q
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRDQ  244

Query  236  AVFSKKLATIMTNVPIEIDIEEIRSKESFDVEGARHLLRRLQF----KSIIEKIPSLNVE  291
            A +SK LATI T  PI I++++I  + + DV +  ++   ++F    K++  ++P   V 
Sbjct  245  AFLSKTLATINTASPITIGLDDIVYNGP-DVASLSQFYDEMDFVQLKKGLASQMPQEPVA  303

Query  292  AEKSDFVVEYNLIDEFPKFHELFSA--------IKDT---EIYMSYSIGNGELYSKIYID  340
                  V+ Y+ + + +   +LFSA        ++D    E  ++++ G+GE   +IY  
Sbjct  304  ------VISYQEVTNVSA--DLFSAEDIFYFETLRDNYHREAIIGFAWGHGE---QIYAS  352

Query  341  TIFMKVEEKTYIVDLKKIIEQNREDVLKDLKEF-FENKKIAKIIHDSKNMYTVLMKNGIK  399
            T +  +   ++    K++++       K +  + F   K+            +L   GI 
Sbjct  353  TDLSLLATDSF----KQVFQ-------KPIATYDFKRSKV------------LLSHLGIE  389

Query  400  IENLAFDTAIAEYLINPSKKEYNLKDAAEEMLLLDLTGEDN--------DIKIKEVYVMD  451
            +   ++D+ +A+YL++    + +L   A     + L  +D          +  K+V +++
Sbjct  390  LVAPSYDARLANYLLSTVEDN-ELSTIARIFTDISLEEDDTVYGKGAKRAVPDKDV-LLE  447

Query  452  KIYNKLK----------DKIKEYDMDELYYKVELPLIEVLSSMESEGFKVEKNKLQQIGD  501
             +  K+K          DK+   +  +LY ++ELPL +VL+ ME EG+KV++  LQ++++
Sbjct  448  HLARKVKVLLDSKSQMLDKLTAHEQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAE  507

Query  502  KFTVEIAKVKDEIYNMAGEEFNISSPKQLGKILFEKLDLPV--IKKTKTGYSTNAEVLEK  559
            +  V I  + +EIY+MAG+EFNI+SPKQLG ILFEK++LP+   KKTKTGYST  +VLE+
Sbjct  508  QNKVIIEALTQEIYDMAGQEFNINSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLER  567

Query  560  LMDKHPIIEKVVYYRQLTKLYSTYVEGLKPVIDVDEKIHSSFNQTVTTTGRLSSTEPNLQ  619
            L    PI+ K++ YRQ+TKL STYV GL+  I  D KIH+ + Q +T TGRLSS +PNLQ
Sbjct  568  LAPIAPIVAKILDYRQITKLQSTYVIGLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQ  627

Query  620  NIPIKNEMGREIRKVFVPENDNCIILSADYSQIELRVLAHIADDENLINAFKHHSDIHTK  679
            NIPI+ E GR IRK F P +++ ++LS+DYSQIELRVLAHI++DE+LI AF++ +DIHT 
Sbjct  628  NIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTS  687

Query  680  TASEVFRVP-IEEVTSRMRSNAKAVNFGIVYGISDFSLAQDIKVSKKEAKEYIDTYFERY  738
            TA  VF +    +VT+  R NAKAVNFGIVYGISDF+L++++ +++K++K YIDTYFERY
Sbjct  688  TAMRVFGIDKAADVTANDRRNAKAVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERY  747

Query  739  PNVKKYLEDIVVTAKKNMYVNTIMNRRRIIPEIASSNKIVKGFGERLAMNTPIQGSAADL  798
            P +K Y+E++V  AK + YV+T+ +RRR +P+I S N  V++F+ER A+N+PIQGSAAD+
Sbjct  748  PGIKAYMENVVREAKDKGYVETLFKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADI  807

Query  799  IKLSMVNVYSKIKQLKLKSRLILQVHDELILNVHkdelekvkelvklemeevmelkvple  858
            +K++M+N+   ++   ++++++LQVHDE++L+V +DEL  +K LVK  ME  ++L VPL 
Sbjct  808  LKIAMINLDKALQAGGFRAKMLLQVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLC  867

Query  859  vDIESGNTWYEAK  871
            VD  +G++WYEAK
Sbjct  868  VDESTGQSWYEAK  880

468) Clos_1206 in NC_009922


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  524 bits (1977),  Expect = 1e-149, Method: Compositional matrix adjust.
 Identities = 375/907 (42%), Positives = 590/907 (66%), Gaps = 46/907 (5%)

Query  3    KRIVIIDGNSLINRAFYAL----PPLTNKEGQHTNAIYGFVTMLLKVMEDYAPDYIGVAF  58
            +++++IDG+S+  RAF+AL      + N  G HTNAIYGF  ML  +M    P  + VAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  59   DKKAPTFRHKEYTEYKAGRKGMPPELAEQLEPLKQVLDALNIYRIELEGFEADDLIGTLA  118
            D    TFR   Y++YKAGR   P E+ EQ+  ++++L AL I   ELE +EADD+IGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  119  KHCEAQGI--ESLIVTGDRDALQLTSDTTKVLFTKKGISQLEIYDAKKVMEDYEVTPTQF  176
            K  E   +  +  IV+GD+D +QLT + T V ++KKG++++E + +  +ME   +TP QF
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  177  IDLKGLMGDKSDNIPGVPGVGEKTAIKLLKQFETIENMIQNTSEIAADKLRQKIEENIEM  236
            IDLK+LMGDKSDNIPGV  +GEKT++KLL +F ++E + ++   + + K+++++ ++ + 
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRDQ  244

Query  237  AVLSKRLATIVTNVPVEMDLDILRKKEFDYERLIELFRMYEFNSLIPRIKKNMEQTQEIS  296
            A LSK LATI T  P+ ++LD +  +  D   L +++   +F  L   +  +M Q     
Sbjct  245  AFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQ-----  299

Query  297  TANLGNRENIVAIKDTDALKKALEEIREQGQMVLKTITEENNIVTDRIVALAMTTTGEIQ  356
                 +   +++ ++   +   L  +  ++   + T+ ++ +   + I+++A     +I 
Sbjct  300  -----EPVAVISYQEVTNVSADL--FSAEDIFYFETLRDNYH--REAIIGFAWGHGEQI-  349

Query  357  YYIEFKDFKESDI----ISPLKDILEDEHIRIIGHDLKKEIIHFYPYEIHIANLYFDTMV  412
                   +  +D+      ++K++++     I   D+K+  + +    I++    +D+ +
Sbjct  350  -------YASTDLSLLATDSFKQVFQK---PIATYDFKRSKVLLSHLGIELVAPSYDARL  399

Query  413  GEYLLNPAKSSYLLKDLALEYLGEEIIDEEKIVGKGKNQLSLWAAPENEVK-ALLCNHVK  471
            ++YLL+    +  L  +A  + +  + +++ + GKG +    +A P+++V    L   VK
Sbjct  400  ANYLLSTVEDN-ELSTIARIFTDISLEEDDTVYGKGAK----RAVPDKDVLLEHLARKVK  454

Query  472  VIAELAKYIQEKIEDQGIHKLYYEVELPLVEVLASMEFLGIKVDRNMLLALEVEFKEIID  531
            V+ +    + +K+  +    LY ++ELPL +VLA ME+ GIKV+R  L  +  + K II+
Sbjct  455  VLLDSKSQMLDKLTAHEQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIE  514

Query  532  KLTSEIYSLAGISFNINSPKQLGEVLFEklglp--ptkktktgYSTNADVLEKLQDQHEI  589
             LT EIY +AG  FNINSPKQLG +LFEK+ LP   TKKTKTGYST  DVLE+L     I
Sbjct  515  ALTQEIYDMAGQEFNINSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPI  574

Query  590  IPKISEYRQVTKLKTTYVDGLLSIINPVTNRIHSSFNQTVTATGRISSTEPNLQNIPVRL  649
            ++KI +YRQ+TKL++TYV GL   I +   +IH+ + Q +T TGR+SS +PNLQNIP+RL
Sbjct  575  VAKILDYRQITKLQSTYVIGLQDYILA-DGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRL  633

Query  650  EMGRRLRKVFISKEGHE-FIDADYSQIELRVLAHIAKDDNLIDAFIKNQDIHTRTASEIF  708
            E GR +RK F + + +  ++ +DYSQIELRVLAHI+ D++LI AF    DIHT TA  +F
Sbjct  634  EQGRLIRKAFTPSHEDAVLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVF  693

Query  709  EVPME-EVTSLMRGDAKAVNFGIVYGISDFGLSQNLNIPVSKAKKYIESYFEKYPSIKEY  767
             +    +VT+  R +AKAVNFGIVYGISDFGLS+NL I   ++K YI++YFE+YP+IK Y
Sbjct  694  GIDKAADVTANDRRNAKAVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAY  753

Query  768  MHNIVEEGKEKGYVVTLLNRRRYLPELKSSNFNIRSFGERIAMNTPIQGSAADIIKIAMI  827
            M+N+V E+K+KGYV TL++RRR LP+++S NFN+RSF+ER A+N+PIQGSAADI+KIAMI
Sbjct  754  MENVVREAKDKGYVETLFKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMI  813

Query  828  AVYNRLKAENYDAKLILQVHDELIIECPENEIEEVSKILKESMENAIEMVVPLKVDLSYA  887
             + + L+A  + AK++LQVHDE+++E P++E+  + K++K++ME A+++ VPL VD S +
Sbjct  814  NLDKALQAGGFRAKMLLQVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTG  873

Query  888  NNWYDAK  894
            ++WY+AK
Sbjct  874  QSWYEAK  880

469) Slip_1695 in NC_014220


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  524 bits (1976),  Expect = 1e-149, Method: Compositional matrix adjust.
 Identities = 371/899 (42%), Positives = 587/899 (66%), Gaps = 57/899 (6%)

Query  2    GQERVMIIDGNSLLYRAFYAL----PLLRNRRGTFTNAVYGFLNMLSKVLSEYQPSHIIV  57
             ++++++IDG+S+ +RAF+AL      ++N+ G  TNA+YGF  ML  ++   +P+H++V
Sbjct  3    NKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLV  62

Query  58   AFDKDRKTLRSEEYGEYKIHRPPAPPELREQFGILREVLEALNVSYIEMSGYEADDIIGT  117
            AFD ++ T+R+E Y++YK  R+ +P E+REQF+ +RE+L AL ++Y E+  YEADDIIGT
Sbjct  63   AFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGT  122

Query  118  LSVRAGEQGLP--CIIVTGDQDELQLVSPGIEVLVTKKGISEMERYDLQAVHGKWEVSPY  175
            L   A    +P    IV+GD+D +QL      V ++KKG++E E +    +  K  ++P 
Sbjct  123  LDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPN  182

Query  176  QLPDVKGLMGDASDNIPGVPGIGRKTAIKLVKQYGSLEGIYANLNEITPVRLRELLTAHK  235
            Q+ D+K+LMGD SDNIPGV  IG KT++KL+ ++GSLEGIY +++ +   +++E L  ++
Sbjct  183  QFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDR  242

Query  236  DQAFLSRKLATIVKDVPLEVEFEKlrrrppqrerlvrvYQELEFNSLLKDLDKDKPPAES  295
            DQAFLS+ LATI    P+ + ++ +    P+   L + Y+E++F  L K+L     +++ 
Sbjct  243  DQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGL-----ASQM  297

Query  296  PTGPVIVGDAGQVLDITRDLRPDEEVSLY--LLADYHHPM-----WAKPKSLFVANGEDV  348
            P  PV V    +V +++ DL + E++  +  L  +YH+       W+        +GE++
Sbjct  298  PQEPVAVISYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFAWG--------HGEQI  349

Query  349  YVFEMEQDPRAALEKLRAFLENEEIGKLVHNGKF--IEVVLKRYGLKFDGVRGDTLLLSY  406
            Y          +L    +F  ++ + K +    F    V+L + G+ + +   D+ L +Y
Sbjct  350  YA-----STDLSLLATDSF--KQVFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANY  402

Query  407  VLDPG-----------FSGETLSEHLFHYLGEVVDEKMDPGLAVRGL-KKLHQVLE----  450
            +L              F++ +L E+   Y         D ++ +  L +K+  +L+    
Sbjct  403  LLSTVEDNELSTIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQ  462

Query  451  --EKLGSQDLVNLYKVVELPLSPVLADMEFTGIKVDPRILAEISQELALRIAEDQARIYQ  508
              +KL +++ ++LY+ +ELPL+ VLA ME+ GIKV+   L +++++  + I      IY+
Sbjct  463  MLDKLTAHEQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYD  522

Query  509  VAGQEFNINSTRQLGKVLFEDLGLP--PVKKTKTGYSTSAEVLEELYGSHEIIEHIVEYR  566
            +AGQEFNINS +QLG +LFE + LP    KKTKTGYST+ +VLE L     I+  I++YR
Sbjct  523  MAGQEFNINSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYR  582

Query  567  TLAKLKSTYVDTFPGYIHPETGRVHTVFKQAVTATGRLSSVEPNLQNIPIRMEEGRRIRK  626
             ++KL+STYV  + +YI ++ G++HT + Q +T TGRLSSV+PNLQNIPIR+E+GR IRK
Sbjct  583  QITKLQSTYVIGLQDYILAD-GKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRK  641

Query  627  AFVPGDENHILLSCDYSQIDLRSLAHMSGDENLIETFRQGIDIHHRTASEIFKVP-LDQV  685
            AF P++E+ +LLS DYSQI+LR LAH+SGDE+LI +F +G DIH  TA  +F +    +V
Sbjct  642  AFTPSHEDAVLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADV  701

Query  686  TPDLRRKAKAVNFGIVYGISDFGLARGTGVTREEAKAYIERYLDSYPGVRRYMQEVVAMG  745
            T++ RR+AKAVNFGIVYGISDFGL+   G+TR ++K+YI+ Y++ YPG++ YM++VV  +
Sbjct  702  TANDRRNAKAVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREA  761

Query  746  REKGYVSTVLGRRRYLPDLLSSNRTVRSMAERMALNAPIQGTSADIIKLAMLSVYRELKR  805
            ++KGYV T++ RRR LPD+ S N  VRS AER A+N+PIQG++ADI+K+AM+++ + L+ 
Sbjct  762  KDKGYVETLFKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQA  821

Query  806  RNLRSRMLLQVHDDlvfevpleeleevallvRDCMENAFelkvplevevkvGANWYDMK  864
              +R++MLLQVHD++V+EVP +EL  +  LV+D ME A +L VPL V+   G +WY+ K
Sbjct  822  GGFRAKMLLQVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

470) Daud_1403 in NC_010424


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  524 bits (1977),  Expect = 1e-149, Method: Compositional matrix adjust.
 Identities = 362/901 (41%), Positives = 586/901 (66%), Gaps = 62/901 (6%)

Query  2    AKFLVIDGNSLLHRA----YHAIPPLTTSGGLPTNAVYGFTNMLLRVITEEQPDMIAVAF  57
             K+L+IDG+S+  RA    Y+ I  +   +GL TNA+YGF  ML +++   +P  + VAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  58   DKGRITFRHDTFQEYKAQRPPMPDDLRPQLPILKDVLGALRISIHEAEGYEADDIIGTLV  117
            D G+ TFR + + +YKA R+  PD++R Q++ ++++L AL I+  E E YEADDIIGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  118  RVA--SENGHDSLILTGDKDILQLVGPHTQALLTRKGITELERYDMAKTRERFGITPAQL  175
            ++A  +E   D  I++GDKD++QL + +T   +++KG++E+E +  A   E+ G+TP Q+
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  176  ADLKGLVGDPSDNIPGVPGIGPKIAARLLADHGRLESVLENLDGL-PPRVRQQLENFGDQ  234
             DLK+L+GD SDNIPGV  IG K + +LL + G LE++ E++DG+  ++++++L N  DQ
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRDQ  244

Query  235  ARMSKKLATIDTGVP-GLGKEDLKVWPGPDKPALLEIFNKLEF----RSLVRRITEAPVT  289
            A +SK LATI+T+ P  +G +D+ V  GPD ++L ++++ ++F    ++L  ++ + PV 
Sbjct  245  AFLSKTLATINTASPITIGLDDI-VYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEPV-  302

Query  290  GGVPAGKPVEAFSPDYRLLDGPD--HLETLLDQarragavavayargrSGIEALGFSVEA  347
             +V + + V   S+D  L+ + D   +ETL D+ +R             +I +++ +   
Sbjct  303  -AVISYQEVTNVSAD--LFSAEDIFYFETLRDNYHR------------EAIIGFAWGHGE  347

Query  348  GNYLLPLGAADLEILA--GVRRLFADAAVAKHMHNAKDFLRWAPDFDLANICFDSMVAAY  405
              Y    +++DL +LA  + +++F  +  + +   +K +L    +++L    +D+ +A Y
Sbjct  348  QIY----ASTDLSLLATDSFKQVFQKPIATYDFKRSKVLLS-HLGIELVAPSYDARLANY  402

Query  406  LVNPLAANQQLEDVVHQYLNLVLVPDGpaapataaDCI-----------RRLYPVLRAE-  453
            L++ +  +++L  + + + ++ L  D+      A   +           R++  +L +  
Sbjct  403  LLSTVE-DNELSTIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKS  461

Query  454  -----LRGYE-LDYLFDRVELPLTRVLADMELAGVAVDRDQLEALSEEFGTRAGELAARI  507
                 L + E LD L++ +ELPL+ VLA ME+ G+ V+R  L+ ++E+       L+  I
Sbjct  462  QMLDKLTAHEQLD-LYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEI  520

Query  508  CTLAGEDFNLNSPRQLGYILFEKLGLP--AGKKTKTGYSTDAGVLLDLAEKHEIAALLLE  565
              +AG++FN+NSP+QLG ILFEK+ LP    KKTKTGYST  +VL  LA    I A +L+
Sbjct  521  YDMAGQEFNINSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILD  580

Query  566  YRQLIKLKTTYADGLAALVDPATGRLHTTLHQTVTNTGRLSSAEPNLQNIPIRMEEGRRI  625
            YRQ+ KL++TY  GL   +  A G++HT   Q +T+TGRLSS +PNLQNIPIR+E+GR I
Sbjct  581  YRQITKLQSTYVIGLQDYI-LADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLI  639

Query  626  RKVFIPRDPARVLLTADYSQIELRILAHLSGDPALITAFRDEQDIHARTAAEVFGVPLEM  685
            RK F P +   VLL++DYSQIELR+LAH+SGD  LI+AF +  DIH+ TA  VFG+    
Sbjct  640  RKAFTPSHEDAVLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAA  699

Query  686  -VTPEMRSRAKAVNFGIIYGISDFGLARDLKVTRAEAREYIQRYFARLPGVKEYIDTAIR  744
             VT++ R  AKAVNFGI+YGISDFGL+ +L +TR +++ YI+ YF R PG+K Y++  +R
Sbjct  700  DVTANDRRNAKAVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVR  759

Query  745  SARERGYVTTALNRRRPLPELFSANHTVRSFGERAAVNTPIQGTAADIIKLAMVKIHARM  804
             A+++GYV T ++RRR LP++ S N  VRSF+ER+A+N+PIQG+AADI+K+AM++++  +
Sbjct  760  EAKDKGYVETLFKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKAL  819

Query  805  RERNLKTLMILQVHDELLFDVPAEEVCTVAPLVKAEMETVLPLNVPLTVDLKIGHNWYEV  864
            +   +++ M+LQVHDE++++VP +E+ ++  LVK  ME+ + L VPL VD   G++WYE 
Sbjct  820  QAGGFRAKMLLQVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEA  879

Query  865  R  865
            +
Sbjct  880  K  880

471) Swol_2017 in NC_008346


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  521 bits (1964),  Expect = 1e-148, Method: Compositional matrix adjust.
 Identities = 372/899 (42%), Positives = 603/899 (68%), Gaps = 62/899 (6%)

Query  3    DKFILIDGNSLLYRAFYAL----PLLHNSAGVYTNGVYGFLTMFNRVLAEIQPTHIAVAF  58
            +K++LIDG+S+ +RAF+AL      + N +G+ TN++YGF  M+++++  ++PTH+ VAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  59   DKDRSTFRNELYSEYKANRSAPPEELGGQFQLLRDVLAALNIEYLEMQGYEADDIIGTLS  118
            D +++TFR E+Y++YKA R+  P+E+  QF  +R++L+AL I Y E++ YEADDIIGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  119  KKAE--EQGLKTVILTGDGDAlqlvseqvevllTKKGISEMELYDPQGVKDKWGVEPEKM  176
            K AE  E  +   I++GD D +QL  E+  V ++KKG++E E + P  + +K G+ P++ 
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  177  VEIKGLMGDASDNIPGVPGVGPKTAMKLVQEFTSLENLYENLPQVKGKKLVEKLEQNREQ  236
            +++K+LMGD SDNIPGV  +G KT++KL++EF SLE +YE++   K  K+ E+L ++R+Q
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRDQ  244

Query  237  AFLSRQLATINRDMELDFSIEDYVMREPHYPELLELYRSLEFNNFLKILQEKEREKGMAP  296
            AFLS+ LATIN    + ++++D V   P+ + L ++Y  ++F ++ K L  +  +  +A 
Sbjct  245  AFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEPVAV  304

Query  297  LKQEIEVLFLEREEDVTALLEEIKQGESVALYFQS---SYHHPMWASLQGVFLEYSERVY  353
            +       +    ++VT +  ++  +E + +YF++   +YH   + ++ G     +E++Y
Sbjct  305  IS------Y----QEVTNVSADLFSAEDI-FYFETLRDNYH---REAIIGFAWGHGEQIY  350

Query  354  ---QLKLEAGDDYKLQWIKALLESAVIKKYLHNAKFIQVLLLRHGIELRGVAGDTMLLAY  410
               +L L A D +K    K+      I  Y  + K  +VLL + GIEL + + D+ L  Y
Sbjct  351  ASTDLSLLATDSFKQVFQKP------IATY--DFKRSKVLLSHLGIELVAPSYDARLANY  402

Query  411  VDDPAFEGDELDACLKKHLQLNIAENN-----------------LAALVNTIRELYFQLE  453
            +     E++EL +  +   ++++ E++                 L  L   ++ L ++  
Sbjct  403  LLSTV-EDNELSTIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVL-LDSK  460

Query  454  GQIPAELR-----ELLQEVEMPMSEVLARMEFCGVKVERSTLARISEELASGIAGHEERI  508
            +Q+   L      +L Q++E+P+++VLA+ME+ G+KV+R+TL  ++E+    I +  + I
Sbjct  461  SQMLDKLTAHEQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEI  520

Query  509  FELAGSSFNINSPKQLGKVLFE--DLGLRVIKKGKTGYSTGAEVLEELYQEHEIIAHILN  566
            +++AG  FNINSPKQLG +LFE  +L L + KK KTGYST+ +VLE L     I+A IL+
Sbjct  521  YDMAGQEFNINSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILD  580

Query  567  YRQLSKIKSTYADALQELIHPETGRVHTIFKQAQTATGRLSSVEPNLQNIPIRMEEGRRI  626
            YRQ++K++STY  +LQ+ I ++ G++HT + Q  T TGRLSSV+PNLQNIPIR+E+GR I
Sbjct  581  YRQITKLQSTYVIGLQDYILAD-GKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLI  639

Query  627  RQAFVAPGPDWLIMAADYSQIDLRSLAHISGDERLIETFKSGVDIHTRTAVEIFHVP-VE  685
            R+AF ++  D +++++DYSQI+LR LAHISGDE+LI +F+ G DIHT TA+ +F +    
Sbjct  640  RKAFTPSHEDAVLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAA  699

Query  686  WVDSELRRRAKAVNFGIIYGISDFGLARDTGVSRKEARKYIDNYLNSYPGVKKYMEDIVE  745
             V ++ RR AKAVNFGI+YGISDFGL+ + G++RK+++ YID Y++ YPG+K YME++V 
Sbjct  700  DVTANDRRNAKAVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVR  759

Query  746  FGRRHGYVETLLKRRRYLPELNARNKMVQAFGRRMALNTPVQGTSADIIKLAMIKVDEEI  805
             ++  GYVETL+KRRR LP++N+RN  V++F+ R A+N+P+QG++ADI+K+AMI++D  +
Sbjct  760  EAKDKGYVETLFKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKAL  819

Query  806  rkrrlqarlllqvhdelllelprteleeVSGLLRDCMENACSLKVPLEVSLKTGPNWYE  864
            +   ++A++LLQVHDE++LE+P  EL  +  L++D ME A  L VPL V   TG +WYE
Sbjct  820  QAGGFRAKMLLQVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYE  878

472) Clocel_2730 in NC_014393


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  520 bits (1960),  Expect = 2e-148, Method: Compositional matrix adjust.
 Identities = 391/897 (44%), Positives = 606/897 (68%), Gaps = 57/897 (6%)

Query  2    GKLVILDGHSLMNRAFYA----IPPLTTAEGLHTNAIFGFINMLFKIREDIKPDYIVTTF  57
             KL+++DG S+  RAF+A    I  +    GLHTNAI+GF  ML  +   ++P  ++ +F
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  58   DRKAPTFRHEEYQDYKAGRKRMPDELHEQFEPLKDILSKMAINIFEIDGFEADDLIGTLA  117
            D    TFR E Y DYKAGR + PDE++EQF  ++++L+ ++I  +E++ +EADD+IGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  118  VKAESEGI--EVYIVTGDRDALQLASDNIKVLLTKKGVSEREVYDRNRMIEDYGVTPTQF  175
              AE   +  +V IV+GD+D +QL+ +N  V ++KKGV+E E +    ++E  G+TP QF
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  176  IDVKGLMGDASDNIPGVPGIGEKTAYKLIKEYGSIEGVLDNLDKLK-GKIKENLESHCED  234
            ID+K+LMGD SDNIPGV  IGEKT+ KL+ E+GS+EG+ +++D +K +K+KENL ++ ++
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRDQ  244

Query  235  AIFSKKLATIITNVPIDIDLDDIKSQEAYDVKALRELFFKYQFKSLINKLPEEENQGQKP  294
            A++SK LATI T  PI I+LDDI  + + DV +L +++   +F  L + L+     +Q P
Sbjct  245  AFLSKTLATINTASPITIGLDDIVYNGP-DVASLSQFYDEMDFVQLKKGLA-----SQMP  298

Query  295  AVEVVIEKISTLVDFEKLTENVDTELFIVHEISGKEKFSLMKLEKLYIHNSK-SYE-IEV  352
               V +      + ++ +T NV ++LF  ++I     F +  L   Y +++  ++   + 
Sbjct  299  QEPVAV------ISYQEVT-NVSADLFSAEDI-----FYFETLRDNYHREAIIGFAWGHG  346

Query  353  QKLFEENEEK--SKEYLKKLFENTSEKI-IHNAKNLFTVLSKLDIDINNFVFDTEIAAYL  409
            ++++   +    + + +K++F++      +  +K L   LS L+I++    +D+ +A YL
Sbjct  347  EQIYASTDLSLLATDSFKQVFQKPIATYDFKRSKVL---LSHLGIELVAPSYDARLANYL  403

Query  410  IESSDKE--YTLKTLF-ETYLHE---TY-QDISQEISNLSNLYQRLKEKIKEL-----QM  457
            + + + +   T+  +F +  L+E    Y ++  + +++   L ++L  K+K L     QM
Sbjct  404  LSTVEDNELSTIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQM  463

Query  458  -------EDL-LY-KIELPLVKVLADMEKVGFKVDREQLDQLREKFINEITVSQKEIYEM  508
                   E+L LY +IELPL +VLA ME  G+KV+R  L+++ E+    I    +EIY+M
Sbjct  464  LDKLTAHEQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDM  523

Query  509  AGEEFNISSPKQLGKILFEKLDLP--VIKKTKTGYSTNAEVLEKLKDKHPIIDKITYYRQ  566
            AG+EFNI+SPKQLG ILFEK++LP  + KKTKTGYST  +VLE+L    PI+ KI  YRQ
Sbjct  524  AGQEFNINSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQ  583

Query  567  LTKLNSTYVEGLIHVIDQDGRIHSSFNQTVTTTGRLSSTEPNLQNIPIKYEMGRAIRKVF  626
            +TKL+STYV GL + I  DG+IH+ + Q +T TGRLSS +PNLQNIPI+ E GR IRK F
Sbjct  584  ITKLQSTYVIGLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAF  643

Query  627  VPNDEESLILSADYSQIELRVLAHMADDENMKTAYLEHIDIHTKTASEVFNLP-LDQVTK  685
             P++E++++LS+DYSQIELRVLAH+++DE++ +A+ E  DIHT TA  VF +    +VT 
Sbjct  644  TPSHEDAVLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTA  703

Query  686  EKRSAAKAVNFGIVYGISDFALSEDLKISKKEAKQYIDTYFSRYPKVKEYISSTIAKAEK  745
            + R  AKAVNFGIVYGISDF+LS++L I++K++K YIDTYF RYP +K Y+ + +  A  
Sbjct  704  NDRRNAKAVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKD  763

Query  746  ELYVNTIFNRRRFIPEITSSNKIVKALGDRLAMNAPIQGSAADIIKLAMVNVskrlkeek  805
              YV+T+F+RRR +P+I S N  V+++++R A+N+PIQGSAADI+K+AM+N+ K L+   
Sbjct  764  KGYVETLFKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGG  823

Query  806  lksslilQVHDEIILNVYkdeletvkelvkkeMESVIDFSVPLEVDINTGTTWYDAK  862
            +++ ++LQVHDEI+L+V +DEL ++K LVK  ME+ +D++VPL VD +TG +WY+AK
Sbjct  824  FRAKMLLQVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

473) Desde_1951 in NC_018017


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  520 bits (1960),  Expect = 2e-148, Method: Compositional matrix adjust.
 Identities = 376/900 (42%), Positives = 575/900 (64%), Gaps = 61/900 (6%)

Query  29   SKILILDGNSLANRAFYAL----PMMTTADGKPTNVLHGFMTMVLRLLLEQKPDYWVVAF  84
            +K+L++DG+S+A RAF+AL           G  TN + GF  M+ +++   +P   +VAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  85   DKTKATVRIEQYADYKAQRKETPDALKPQFDFLKELLTAFSMPILECAGYEADDIIATVA  144
            D  K+T R E YADYKA R  TPD ++ QF +++E+LTA++++  E   YEADDII+T+ 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  145  SMAEKRE--WETQIYTGDRDALQLISPRTTVYLTRKGITEVDAYDEAALYEKYQLRPAQI  202
             MAE+ E   +  I +GD+D +QL    T V +++KG++E + +  A L EK  L P Q+
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  203  IDLKGLMGDASDNIPGVPGVGEKTALKLLWEYGSVENVLENIDNISGKKLQENLRNNTDK  262
            IDLK+LMGD SDNIPGV  +GEKT+LKLL E+GS+E + E+ID +   K++ENL N+ D+
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRDQ  244

Query  263  ALLSKKLATMLYDIPTEIDLDKLAYRRPDEKVFAGALDKYVLKSVARIWhehhgigeeer  322
            A+LSK LAT+    P  I+LD + Y  PD            + S++++ +E + +     
Sbjct  245  AFLSKTLATINTASPITIGLDDIVYNGPD------------VASLSQFYDEMDFVQLKKG  292

Query  323  gTAQ--EEALKPWPLRELSTEEWLVQLAKWQADTTPLILTYGSTGGNPHWGKVTD--WGM  378
             ++Q  +E++   + +E++     V      A+    I+ + +  +N H+  + +  WG 
Sbjct  293  LASQMPQEPVAVISYQEVTN----VSADLFSAED---IFYFETLRDNYHREAIIGFAWGH  345

Query  379  AAEGESFILNWTDADPEVRQAFIHLLEDPAVSKQVGDSKLLYSLLLNEEINLRGVALDIS  438
            + +    I   TD      ++F ++++ P  + +   SK+L S L    I+L + + D  
Sbjct  346  GEQ----IYASTDLSLLATDSFKQVFQKPIATYDFKRSKVLLSHL---GIELVAPSYDAR  398

Query  439  LAAYLINPTRNK--------FESLELVKE---YIPG----VGEFGNLAEE-ASALAQVVD  482
            LA YL++   ++        F  + L  +   Y  G    V + + L E+ A  +  ++D
Sbjct  399  LANYLLSTVEDNELSTIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLD  458

Query  483  SYKETLEELGLS---ALLHEMEEPLSPILARMEKQGIAVDVQRLKEFGQELTVELQRLEQ  539
            S  + L+ L       L +++E PL+ +LA+ME +GI V+   L++ +++  V ++ L Q
Sbjct  459  SKSQMLDKLTAHEQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQ  518

Query  540  EIYADAGETFNINSPQQLGHILFEKLGLP--PMKKTKTGYSTDADTLEELRTQHPIVDKV  597
            EIY  AG+ FNINSP+QLG ILFEK+ LP    KKTKTGYST  D LE L    PIV K+
Sbjct  519  EIYDMAGQEFNINSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKI  578

Query  598  LDYRQLSKLMSTYVNGLLAQI-HEERVHTTFQQTVTATGRLSSTEPNLQNIPIRLELGRL  656
            LDYRQ++KL STYV GL   I  + ++HT + Q +T TGRLSS +PNLQNIPIRLE GRL
Sbjct  579  LDYRQITKLQSTYVIGLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRL  638

Query  657  LRKVFTPTQEGWVLLSADYSQIELRILAHYSQDQVLCESFSLNQDVHTRTASEVFGVPME  716
            +RK FTP++E+ VLLS+DYSQIELR+LAH S D+ L  +F+   D+HT TA  VFG+   
Sbjct  639  IRKAFTPSHEDAVLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKA  698

Query  717  -DVTKDMRRKAKAVNFGLIYGLTDFGLGRDLGVPRKEAKTYIEKYFHRYEGVKRYLEEIV  775
             DVT + RR+AKAVNFG++YG++DFGL+ +LG+ RK++K+YI+ YF+RY G+K Y+E++V
Sbjct  699  ADVTANDRRNAKAVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVV  758

Query  776  VKAKEEAQVRTLLNRLRRIPELRHPNRVQRQFGERIAMNTPIQGTAADVMKLAMLGVAEA  835
              AK+ + V TL++R R +P++   N   R F+ER A+N+PIQG+AAD++K+AM+ +  A
Sbjct  759  REAKDKGYVETLFKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKA  818

Query  836  LKP--YRANLLLQVHDELVIEVAPEDVEEVAKVVRDEMENAFPLSVPLTVECKTGPNWYD  893
            L++  +RA++LLQVHDE+V+EV+ +++  + K+V+D ME A  L+VPL V+  TG +WY+
Sbjct  819  LQAGGFRAKMLLQVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYE  878

474) Amet_3125 in NC_009633


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  520 bits (1962),  Expect = 2e-148, Method: Compositional matrix adjust.
 Identities = 368/904 (41%), Positives = 601/904 (67%), Gaps = 38/904 (4%)

Query  4    KRMVIIDGNSLINRAFYAL----PPLTNKEGQHTNAIYGFMTMLLKVMDDYDPQYISVAF  59
            +++++IDG+S+  RAF+AL      + N  G HTNAIYGF  ML  +M    P  + VAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  60   DRKAPTFRHKSFEGYKAGRKKMPPELAEQLEPLKEVLDAFHIYRVEIDGFEADDLIGTLS  119
            D    TFR   + +YKAGR K P E+ EQ+  ++E+L A+ I   E++ +EADD+IGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  120  KYAEEQDI--ECLIVTGDKDALQLASEKVKILFTKKGISSLEIYDPQKIMEQYEVTPEQF  177
            K AE  ++  +  IV+GDKD +QL+ E+  + ++KKG++ +E + P  +ME+  +TP+QF
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  178  IDLKGLMGDNSDNIPGIPGVGEKTAIKLLKQFGTVENLIQNAGEISAQKLREKVENNTEQ  237
            IDLK+LMGD+SDNIPG+  +GEKT++KLL +FG++E + ++ + + + K++E++ N+ +Q
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRDQ  244

Query  238  AMMSKRLATIMTNVPVEIELEKLKKIAIDEEKVLALFKKFEFNTLIGRVIARKEEVDGEV  297
            A +SK LATI T  P+ I L+ +   + D   +  ++   +F  L  + +A +   +   
Sbjct  245  AFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQL-KKGLASQMPQEPVA  303

Query  298  VVKQEKMTNEIAQITNIDELKKAFDEVRAGKQMILQTKTEEENIVLDHILAITFSVNGEK  357
            V+  + +TN  A++ + +++   F+ +R   +              + I++++ + +GE+
Sbjct  304  VISYQEVTNVSADLFSAEDIF-YFETLRDNYHR-------------EAIIGFAWG-HGEQ  348

Query  358  LYYIDVRDFSDKEALLIQIKEVLEDEEIHKIGHDIKHEIRHFYVHDIEMKNVTFDTMIGE  417
            +Y      +   +++    K+V++         D+K+    +   +IE+   ++D+ +++
Sbjct  349  IYASTDLSLLATDSF----KQVFQK---PIATYDFKRSKVLLSHLGIELVAPSYDARLAN  401

Query  418  YLIDPAKSSYALKDLAAQYIGQEVMSEEELRGKGKNLISIGEAPKEDLMKYLCQRVSVIG  477
            YL+     +  L  +A  + +  +  ++ + GKG +    + + K+ L+  L ++V V+ 
Sbjct  402  YLLSTVEDN-ELSTIARIFTDISLEEDDTVYGKGAK---RAVPDKDVLLEHLARKVKVLL  457

Query  478  KIYPEIKAKMQeleleklyyevelplvevlAAMEYKGIKVDRSMLEILEIEFGEQIDLLT  537
               +++  K+   E   LY ++ELPL +VLA ME  GIKV+R+ L+ +  +    I+ LT
Sbjct  458  DSKSQMLDKLTAHEQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALT  517

Query  538  KAIHELAETNFNINSPKQLGEVLFEKLELP--PIKKTKTGYSTNAEVLEKLQDQHDIIPK  595
            + I ++A  +FNINSPKQLG +LFEK++LP    KKTKTGYST  +VLE+L     I++K
Sbjct  518  QEIYDMAGQEFNINSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAK  577

Query  596  ILEYRQVTKLKSTYVDGLLNIINPETGRIHSNFNQTVTTTGRISSTEPNLQNIPIKLEMG  655
            IL+YRQ+TKL+STYV GL + I ++ G+IH+ + Q +T TGR+SS +PNLQNIPI+LE G
Sbjct  578  ILDYRQITKLQSTYVIGLQDYILAD-GKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQG  636

Query  656  RRLRKVFV-ANENHQFIDADYSQVELRVLAHICEDENLLDAFLKNQDIHTRTAAEIFDVP  714
            R +RK F  ++E+  ++ +DYSQ+ELRVLAHI  DE+L+ AF    DIHT TA  +F++ 
Sbjct  637  RLIRKAFTPSHEDAVLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGID  696

Query  715  ME-EVTDSMRSSAKAVNFGIVYGISDYGLSQNLNITRVKAKKYIDNYLDKYPSVKRYMDE  773
               +VT + R +AKAVNFGIVYGISD+GLS+NL ITR ++K YID Y+++YP++K YM++
Sbjct  697  KAADVTANDRRNAKAVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMEN  756

Query  774  IVEQAHQQGYVVTLFNRRRYLPELKSRNFNIRSFGERMAMNTPIQGSAADIIKIAMVNVY  833
            +V +A ++GYV TLF+RRR LP+++SRNFN+RSF+ER A+N+PIQGSAADI+KIAM+N+ 
Sbjct  757  VVREAKDKGYVETLFKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLD  816

Query  834  RRLKEQGLTSKLILQVHDELIVEAPDNEVEVAIKIVRESMEEAMNLKVQLKVDLAYANNW  893
            + L+  G+ +K++LQVHDE+++E P++E+    K+V+++ME A++L V L VD + +++W
Sbjct  817  KALQAGGFRAKMLLQVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSW  876

Query  894  YDAK  897
            Y+AK
Sbjct  877  YEAK  880

475) Clole_2063 in NC_015275


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  517 bits (1952),  Expect = 1e-147, Method: Compositional matrix adjust.
 Identities = 365/900 (41%), Positives = 596/900 (67%), Gaps = 42/900 (4%)

Query  2    KQKLLLFDGHSIANRAFYG----VPLLTNKSGQYTNAIYGFLNMMLSIMEKEKPDYLGIT  57
            K+KLLL+DG S+A RAF++    +  + N SG  TNAIYGF  M+  +M + +P  + ++
Sbjct  4    KNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVA  63

Query  58   FDLSVPTFRHEFSADYKGNRKGMPEELRVQIPLLKKVLKAMHIHIIEKEGFEADDVLGTL  117
            FD +  TFR E  ADYK+ R   P+E+R Q++ ++ +L A+ I   E E +EADD++GTL
Sbjct  64   FDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTL  123

Query  118  AKAGEKAGM--QVTVVSGDRDLFQITSDMIEIKIPRTKKTGTEIESFFAKDVVETYGVSP  175
             K +E++ +  +VT+VSGD+DL+Q+T +   + I  +KK  +E+E F +  ++E  G++P
Sbjct  124  DKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEI--SKKGVAEFEEFTPAYLMEKMGLTP  181

Query  176  IAFVDVKGLMGDASDNIKGVPGIGEKTAIKLIKEYGSIENLLDQVDQITQKKLKENLMTY  235
              F+D+K+LMGD SDNI GV  IGEKT++KL+ E+GS+E + +++D +   K+KENL+  
Sbjct  182  NQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIND  241

Query  236  AQDARDSKMLATIICDVPLVYKWSDFEFDLALDSEATALFRDLEL----KSLLTKLPKMe  291
             ++A  SK LATI    P+     D+ ++ +  +  + ++ ++++    K+L +++P+  
Sbjct  242  RDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEP  301

Query  292  neaiaeaeeVKVEQWKTTDFEKFLQESKDQMVGIAYFVEDNTLGLGVAIGERVGYSEWDL  351
               I+  E  +V        + F  E      +I YF   +TL         +G++ W+ 
Sbjct  302  VAVISYQEVTNVSA------DLFSAE------DIFYF---ETLRDNYHREAIIGFA-WGH  345

Query  352  TDTEAKAVLIEFLESATYQKIVHDSK---NFKHE---LLKVGLGLNGVCFDTFIAAYLLH  405
             +    +  + +L + +++++ + +    +FK+    L  +G+ L +  +D+ +A YLL 
Sbjct  346  GEQIYASTDLSLLATDSFKQVFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLS  405

Query  406  PTNKSYDLAELEELFINKQSLMNLENLLGKGKSQKTWLQLEDEERINNLGKRSQLALSVT  465
              + + +L+ +  +F +  SL + + + GKG  +      + +  +++L+++ ++ L   
Sbjct  406  TVEDN-ELSTIARIFTDI-SLEEDDTVYGKGAKRAV---PDKDVLLEHLARKVKVLLDSK  460

Query  466  EAMKEALQEQNMTRLFYDIEMPLIDVLFDMEVEGIKVDPEGLRSYGEELQGLLDTLTTSI  525
              M + L  ++   L+ +IE+PL +VL  ME+EGIKV+   L+  +E+ + ++++LT  I
Sbjct  461  SQMLDKLTAHEQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEI  520

Query  526  YEAAGESFNINSPKQLGVILFEKLGIP--CAKKTKTGYSTAAEVLEALKNDYPIVAQILE  583
            Y+ AG+ FNINSPKQLG ILFEK+ +P   +KKTKTGYSTA +VLE L    PIVA+IL+
Sbjct  521  YDMAGQEFNINSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILD  580

Query  584  YRQYAKLKSTYVDGLLNVLTEQNKIHSTFNQTITATGRLSSTEPNLQNIPVKFEMGKKIR  643
            YRQ +KL+STYV GL + +  + KIH+ + Q +T TGRLSS +PNLQNIP+++E G+ IR
Sbjct  581  YRQITKLQSTYVIGLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIR  640

Query  644  QLFVPSSENHIFLDGDYSQIELRVLAHMSGDPTLIKAFKENIDIHALTASQVFHVP-FED  702
            + F PS E+ ++L +DYSQIELRVLAH+SGD  LI AF+E  DIH+ TA +VF +    D
Sbjct  641  KAFTPSHEDAVLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAAD  700

Query  703  VTSMQRSNAKAVNFGIVYGISAFALSEDLKISQKEAQKYIDGYFEKYPCIKAYLDEIIDF  762
            VT+ +R NAKAVNFGIVYGIS F+LS++L I++K+++ YID YFE+YP IKAY+++++  
Sbjct  701  VTANDRRNAKAVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVRE  760

Query  763  AMQNGYVETLYHRKREIPEILASNYNMREFGKRVAMNTPIQGTSADIIKIAMIRVHQKLK  822
            A ++GYVETL+ R+RE+P+I + N+N+R F+ R A+N+PIQG++ADI+KIAMI +++ L+
Sbjct  761  AKDKGYVETLFKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQ  820

Query  823  EHSLKSKLILTVHDELLIDAHkdeveivkkllkeeMEHAADLSVPLVVDVHQGANWLAVK  882
              ++++K++L VHDE++++  +DE+  +KKL+K+ ME A DL+VPL VD   G +W   K
Sbjct  821  AGGFRAKMLLQVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

476) Thit_0811 in NC_013921


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  517 bits (1951),  Expect = 1e-147, Method: Compositional matrix adjust.
 Identities = 364/894 (41%), Positives = 589/894 (66%), Gaps = 43/894 (4%)

Query  3    KFLIIDGSSLMYRAYYAL----PMLTTSEGLPTNALYGFTMMLIKLIEEEKPDYIAIAFD  58
            K+L+IDGSS+ +RA++AL      +    GL TNA+YGF +ML  ++   +P  + +AFD
Sbjct  6    KLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAFD  65

Query  59   KKAPTFRHKEYQDYKATRQAMPEELAEQVDYLKEIIDGFNIKTLELEGYEADDIIGTISK  118
                TFR   Y DYKA R   P+E+ EQ  Y++E++ ++ I   ELE YEADDIIGT+ K
Sbjct  66   AGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLDK  125

Query  119  LAEEKGM--EVLVVTGDRDALQLvsdkvkikiskkGITQMEEFDEKAILERYGITPQQFI  176
            +AE   +  +V +V+GD+D +QL  ++  + ISKKG+++ EEF    ++E+ G+TP+QFI
Sbjct  126  MAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQFI  185

Query  177  DLKGLMGDKSDNIPGVPNIGEKTAIKLLKDFGTIENLIQNLSQLKGkikeni-ennkeLA  235
            DLK+LMGDKSDNIPGV +IGEKT++KLL +FG++E + +++  +K     +   N+++ A
Sbjct  186  DLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRDQA  245

Query  236  IMSKRLATIKRDIPIEIDFEE--YKVkkfneekl--lelfnkleffSLIDNIKKESSIEI  291
            ++SK LATI+   PI I++++  Y+            E+       +L  ++ +E+ + +
Sbjct  246  FLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEP-VAV  304

Query  292  VDNHKVEKWSKVDIKELVTLLQDNRNIAFYPLI---YEGEIKKIAFSFGK-DTVY----I  343
            +  +        ++ ++ + L    +I ++  +   Y+ E   I+F+ G  + +Y    +
Sbjct  305  ISYQ--------EVTNVSADLFSAEDIFYFETLRDNYHREAI-IGFAWGHGEQIYASTDL  355

Query  344  DVFQTEDLKEIFEK--EDFEFTTHEIKDFLVRLSYKGIECKSKYIDTAVMAYLLNPSESN  401
             ++ T+ +K++F+K    ++F    +  +L +L   GIE  +   D+ +  YLL+  E N
Sbjct  356  SLLATDSFKQVFQKPIATYDFKRSKV--LLSHL---GIELVAPSYDARLANYLLSTVEDN  410

Query  402  YDLDRVLKKYLKVDVPSYEGIFGKGRDKKKIEEIDENILADYICSRCVYLFDLKEKLMNF  461
             +L  + + +  + +   + ++GKG  K+ +   D ++L + +  +   L+D K ++++ 
Sbjct  411  -ELSTIARIFTDISLEEDDTVYGKG-AKRAVP--DKDVLLEHLARKVKVLLDSKSQMLDK  466

Query  462  IEEMDMKKLLLEIEMPLVEVLKSMEVSGFTLDKEVLKELSQKIDDRIGEILDKIYKEAGY  521
            +   +   L  +IE+PL +VL  ME+ G+ +++  L++++++    I  + + IY  AG 
Sbjct  467  LTAHEQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQ  526

Query  522  QFNVNSPKQLSEFLFEKLNLP--VIKKTKTGYSTDSEVLEQLVPYNDIVSDIIEYRQLTK  579
            +FN+NSPKQL+ +LFEK++LP  + KKTKTGYST  +VLE+L P   IV+ I++YRQ+TK
Sbjct  527  EFNINSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITK  586

Query  580  LKSTYIDGFLPLMDENNRVHSNFKQMVTATGRISSTEPNLQNIPIREEFGRQIRRAFIPR  639
            L+STY+ G+   +  + ++H+ + Q +T TGR+SS +PNLQNIPIR E GR IR+AF P 
Sbjct  587  LQSTYVIGLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPS  646

Query  640  SRDGYIVSADYSQIELRVLAHVSGDEKLIESFMNNEDIHLRTASEVFKVPME-KVTPEMR  698
              D+ ++S+DYSQIELRVLAH+SGDE LI +F +  DIH  TA  VF +     VT++ R
Sbjct  647  HEDAVLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDR  706

Query  699  RAAKAVNFGIIYGISDYGLSRDLKISRKEAKEYINNYFERYKGVKEYIEKIVRFAKENGY  758
            R AKAVNFGI+YGISD+GLS +L I+RK++K YI+ YFERY G+K Y+E++VR AK++GY
Sbjct  707  RNAKAVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGY  766

Query  759  VTTIMNRRRYIPEINSRNFTQRSQAERLAMNAPIQGSAADIIKMAMVKVYNDlkklklks  818
            V T+ +RRR +P+INSRNF  RS AER A+N+PIQGSAADI+K+AM+++ + L+   +++
Sbjct  767  VETLFKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRA  826

Query  819  klilQVHDELVVDTYKDEVDIIKKILKENMENVVQLKVPLVVEIGVGPNWFLAK  872
            K++LQVHDE+V++  +DE+  IKK++K+ ME  V+L VPL V+ + G +W+ AK
Sbjct  827  KMLLQVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

477) Tmath_0850 in NC_014209


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  517 bits (1951),  Expect = 1e-147, Method: Compositional matrix adjust.
 Identities = 364/894 (41%), Positives = 589/894 (66%), Gaps = 43/894 (4%)

Query  3    KFLIIDGSSLMYRAYYAL----PMLTTSEGLPTNALYGFTMMLIKLIEEEKPDYIAIAFD  58
            K+L+IDGSS+ +RA++AL      +    GL TNA+YGF +ML  ++   +P  + +AFD
Sbjct  6    KLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAFD  65

Query  59   KKAPTFRHKEYQDYKATRQAMPEELAEQVDYLKEIIDGFNIKTLELEGYEADDIIGTISK  118
                TFR   Y DYKA R   P+E+ EQ  Y++E++ ++ I   ELE YEADDIIGT+ K
Sbjct  66   AGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLDK  125

Query  119  LAEEKGM--EVLVVTGDRDALQLvsdkvkikiskkGITQMEEFDEKAILERYGITPQQFI  176
            +AE   +  +V +V+GD+D +QL  ++  + ISKKG+++ EEF    ++E+ G+TP+QFI
Sbjct  126  MAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQFI  185

Query  177  DLKGLMGDKSDNIPGVPNIGEKTAIKLLKDFGTIENLIQNLSQLKGkikeni-ennkeLA  235
            DLK+LMGDKSDNIPGV +IGEKT++KLL +FG++E + +++  +K     +   N+++ A
Sbjct  186  DLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRDQA  245

Query  236  IMSKRLATIKRDIPIEIDFEE--YKVkkfneekl--lelfnkleffSLIDNIKKESSIEI  291
            ++SK LATI+   PI I++++  Y+            E+       +L  ++ +E+ + +
Sbjct  246  FLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEP-VAV  304

Query  292  VDNHKVEKWSKVDIKELVTLLQDNRNIAFYPLI---YEGEIKKIAFSFGK-DTVY----I  343
            +  +        ++ ++ + L    +I ++  +   Y+ E   I+F+ G  + +Y    +
Sbjct  305  ISYQ--------EVTNVSADLFSAEDIFYFETLRDNYHREAI-IGFAWGHGEQIYASTDL  355

Query  344  DVFQTEDLKEIFEK--EDFEFTTHEIKDFLVRLSYKGIECKSKYIDTAVMAYLLNPSESN  401
             ++ T+ +K++F+K    ++F    +  +L +L   GIE  +   D+ +  YLL+  E N
Sbjct  356  SLLATDSFKQVFQKPIATYDFKRSKV--LLSHL---GIELVAPSYDARLANYLLSTVEDN  410

Query  402  YDLDRVLKKYLKVDVPSYEGIFGKGRDKKKIEEIDENILADYICSRCVYLFDLKEKLMNF  461
             +L  + + +  + +   + ++GKG  K+ +   D ++L + +  +   L+D K ++++ 
Sbjct  411  -ELSTIARIFTDISLEEDDTVYGKG-AKRAVP--DKDVLLEHLARKVKVLLDSKSQMLDK  466

Query  462  IEEMDMKKLLLEIEMPLVEVLKSMEVSGFTLDKEVLKELSQKIDDRIGEILDKIYKEAGY  521
            +   +   L  +IE+PL +VL  ME+ G+ +++  L++++++    I  + + IY  AG 
Sbjct  467  LTAHEQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQ  526

Query  522  QFNVNSPKQLSEFLFEKLNLP--VIKKTKTGYSTDSEVLEQLVPYNDIVSDIIEYRQLTK  579
            +FN+NSPKQL+ +LFEK++LP  + KKTKTGYST  +VLE+L P   IV+ I++YRQ+TK
Sbjct  527  EFNINSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITK  586

Query  580  LKSTYIDGFLPLMDENNRVHSNFKQMVTATGRISSTEPNLQNIPIREEFGRQIRRAFIPR  639
            L+STY+ G+   +  + ++H+ + Q +T TGR+SS +PNLQNIPIR E GR IR+AF P 
Sbjct  587  LQSTYVIGLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPS  646

Query  640  SRDGYIVSADYSQIELRVLAHVSGDEKLIESFMNNEDIHLRTASEVFKVPME-KVTPEMR  698
              D+ ++S+DYSQIELRVLAH+SGDE LI +F +  DIH  TA  VF +     VT++ R
Sbjct  647  HEDAVLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDR  706

Query  699  RAAKAVNFGIIYGISDYGLSRDLKISRKEAKEYINNYFERYKGVKDYIEKIVRFAKENGY  758
            R AKAVNFGI+YGISD+GLS +L I+RK++K YI+ YFERY G+K Y+E++VR AK++GY
Sbjct  707  RNAKAVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGY  766

Query  759  VTTIMNRRRYIPEINSRNFTQRSQAERLAMNAPIQGSAADIIKMAMVKVYNDlkklklks  818
            V T+ +RRR +P+INSRNF  RS AER A+N+PIQGSAADI+K+AM+++ + L+   +++
Sbjct  767  VETLFKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRA  826

Query  819  klilQVHDELVVDTYKDEVDIIKKILKENMENVVQLKVPLVVEIGVGPNWFLAK  872
            K++LQVHDE+V++  +DE+  IKK++K+ ME  V+L VPL V+ + G +W+ AK
Sbjct  827  KMLLQVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

478) Acear_0340 in NC_014378


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  517 bits (1952),  Expect = 9e-148, Method: Compositional matrix adjust.
 Identities = 368/890 (42%), Positives = 591/890 (67%), Gaps = 39/890 (4%)

Query  1    MEDKKELFLLDGSSLLHRAFYAL---PESLQTSDGEYTNGVFGFTKMLLRLIEEEDPDSL  57
            ME+K+ L+L+DGSS+  RAF+AL    + ++   G  TN+++GF  ML +++    P  +
Sbjct  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60

Query  58   AVAFDLAGPTFRHEEYEEYKANRKETPDKLKPQFGLMKEVLEAFRIPVVELEGYEADDII  117
             VAFD +  TFR E Y +YKA R  TPD ++ QF+ ++E+L A+ I+  ELE YEADDII
Sbjct  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120

Query  118  GTLARQAE--EEGYQVTIVTGDRDALQLVTEQTKIRYTKRGITNIvdydlekveeeyele  175
            GTL + AE  E  ++VTIV+GD+D +QL  E+T +  +K+G++++ ++    + E   L 
Sbjct  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLT  180

Query  176  PRKLIDKKGLMGDKSDNIPGVDGIGKKTSTKLLHQFGSLEEVLDNIDQVSGKKRKQTLKE  235
            P ++ID K+LMGDKSDNIPGV  IG KT+ KLLH+FGSLE + ++ID     K K+ L +
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  236  QADRARMSKKLATIKLDVPIECDLDEFKLEEPDQEKLINILSRLEFNSLLKEFGGHETLN  295
            + D+A +SK LATI+   PI  +LD++  + PD   L ++   ++F  L K ++++   +
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQE  300

Query  296  LTGGFEVIT--DLTEIDRVLSMLDEVESFGFKFNFASTKLYQQKVEGLTVASDEEACYID  353
              +   VI+  ++T++   L   +++    F F+    +  ++ + G++ + +E+     
Sbjct  301  PVA---VISYQEVTNVSADLFSAEDI----FYFETLRDNYHREAIIGFAWGHGEQIY--A  351

Query  354  TSDLDLAELIDKLQPYFEDYELNKLSLNTKENLIYLKEQGVEVKGISFDPLLADYLLRPS  413
            ++DL L       +++ + ++    + + K + + L + G+E+ + S+D+ LA+YLL   
Sbjct  352  STDLSLLAT----DSFKQVFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTV  407

Query  414  AKEQ--DLESILTD-QLQMelekteseaeteVQQ-----------VRILFKLQDKLTDKL  459
              ++   +  I+TD  L+ +       A   V +           V++L+  + ++ DKL
Sbjct  408  EDNELSTIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKL  467

Query  460  ADKGLMELFIDVELPLIPILAQMELNGIAVDQDMIQELSNKLEEKLDSLRSRAYELAGEE  519
            +    ++L+ ++ELPL  +LA+ME++GI V++  +Q+++++    +++L    Y++AG+E
Sbjct  468  TAHEQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQE  527

Query  520  FNLNSPKQLGEILFEKLGLP--VIKRTKTGYSTSASVLEKLEDKHEIVPLILEYRKYQKL  577
            FN+NSPKQLG ILFEK+ LP  + K+TKTGYST+  VLE+L     IV+ IL+YR+  KL
Sbjct  528  FNINSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKL  587

Query  578  KSTYVDPLPDLINPKTERIHTSFNQLVTATGRLSSTEPNLQNIPIRTEEGRRIRKVFV-A  636
            +STYV  L D I +   +IHT + Q +T TGRLSS +PNLQNIPIR E+GR IRK F  +
Sbjct  588  QSTYVIGLQDYILADG-KIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPS  646

Query  637  EERKELLAVDYSQIELRVLAHISQDENLIAAYREGQDIHTKTAAEVFGLE-ASEVSYQQR  695
            +E   LL+ DYSQIELRVLAHIS DE+LIAA+ EG DIHT TA  VFG++ A++V+ ++R
Sbjct  647  HEDAVLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDR  706

Query  696  RRAKAINFGIAYGISPWGLAKDINVSKQEAEDYINQYLNRYPKVKEYMDHQIKQAKEEGY  755
            R AKA+NFGI YGIS  GL++++ ++++++  YI+ Y++RYP +K YM++ +++AK+ GY
Sbjct  707  RNAKAVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGY  766

Query  756  VTTILNRRRYLPEINSSNYHRRSFGERMAINTPIQGSAADIMKLAMLESARVLDERELDT  815
            V T+++RRR LP+INS N++ RSF+ER AIN+PIQGSAADI+K+AM++  + L+   + +
Sbjct  767  VETLFKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRA  826

Query  816  KILLQVHDelifevppeeleevqqviKAEMEDVIELDVPLKVDLKVGSNW  865
            K+LLQVHDE+++EVP +EL  +++++K  ME  ++L VPL VD   G +W
Sbjct  827  KMLLQVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSW  876

479) polA in NC_020291


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  516 bits (1948),  Expect = 2e-147, Method: Compositional matrix adjust.
 Identities = 372/903 (42%), Positives = 597/903 (67%), Gaps = 64/903 (7%)

Query  2    KKLLILDSNSLMNRAFYAL----PPLTNSDGINTNAIYGFINMLFKIKDEINPDSIIATF  57
            +KLL++D++S+  RAF+AL      + N  G++TNAIYGF  ML  +   + P  ++ +F
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  58   DLKAPTFRHKEYAEYKAGRNKMPPELAEQFPIIKDLFKLMGIKIFEIEGFEADDLIGTVS  117
            D    TFR   YA+YKAGR K P E+ EQF+ I++++  +GI  +E+E +EADD+IGT+ 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  118  KFAENNAT--EVAIVTGDKDALQLASDSTKVIITKKGVSETAVYDSKTFIDEFEVTPTQF  175
            K AE      +V+IV+GDKD +QL+ ++T V I+KKGV+E   + +  +++   +TP QF
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  176  IDVKGLMGDKSDNIPGVPGVGEKTAFKLIKEYGSVEEVMKNIDNIPGKKLKENLENNVEQ  235
            ID+K+LMGDKSDNIPGV  +GEKT++KL+ E+GS+E +  +ID +   K+KENL N+ +Q
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRDQ  244

Query  236  AIFSKKLATIMREVPIELTLDDI--NSMEKENIAEIKKMLIKLEMKSILAKFKDDTVSEE  293
            A++SK LATI    PI + LDDI  N+ +  +++++   +  +++K  LA     +   +
Sbjct  245  AFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLA-----SQMPQ  299

Query  294  STVEIKKIHNIKEMKELFLEKKNRIYIDYTLSDASIYSKLELEYLVLGEDNKGIIIYFKD  353
              V +   +++ ++   ++   + +Y++ TL D   Y +  +  +  G++++   IY   
Sbjct  300  EPVAVISYQEVTNVSADLFSAEDIFYFE-TLRDN--YHREAIIGFAWGHGEQ---IY---  350

Query  354  IISENKDEALKVLRTLMEDENIKKVIHDGKNFVTY--------LNKNKIEIKGFDFDTAI  405
                     L    +L+  +++K+V++  K + TY        L+   IE+ +  +D+ +
Sbjct  351  -----ASTDL----SLLATDSFKQVFQ--KPIATYDFKRSKVLLSHLGIELVAPSYDARL  399

Query  406  AAYLIDSSKNKYEILELVNRYIGDNPNTEDENL-----------KGILSSYLP-------  447
            A YL+ +  +  + L  + R + D +  ED+ +           K++L   L+       
Sbjct  400  ANYLLSTVED--NELSTIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLL  457

Query  448  EIYEELKETLHKENMDKLYYEVEHPLIYVLSSMESIGFNINKGMLDELQIKFKKEIEETQ  507
            +   ++ + L  ++   LY ++E PL  VL+ ME  G+++N++ L+++  + K  IE   
Sbjct  458  DSKSQMLDKLTAHEQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALT  517

Query  508  NEIYKLSEEEFNISSPKQLGKILFEKLDLP--VLKKTKTGYSTNQEVLEKLIDKHEIIPK  565
            +EIY ++ +EFNI+SPKQLG ILFEK++LP  + KKTKTGYST  +VLE+L     I++K
Sbjct  518  QEIYDMAGQEFNINSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAK  577

Query  566  IMYYRQITKINSTYVEGLKNVIDEDGRIHSNFNQTVTTTGRLSSTEPNLQNIPIKYEMGR  625
            I+ YRQITK++STYV GL++ I  DG+IH+ + Q +T TGRLSS +PNLQNIPI+ E GR
Sbjct  578  ILDYRQITKLQSTYVIGLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGR  637

Query  626  EIRKVFIPMEETDILVSCDYSQIELRVLAHIAGDENMIDAFEHHSDIHTKTASEVFKVP-  684
             IRK F P +E  +L+S DYSQIELRVLAHI+GDE++I AF++ +DIHT TA  VF +  
Sbjct  638  LIRKAFTPSHEDAVLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDK  697

Query  685  IDEVTSLMRSRAKAVNFGIVYGISAFSLAEDLKISKKEAEEYMSIYLERYPKIKEYLENV  744
              +VT+  R  AKAVNFGIVYGIS F+L+++L I++K++  Y+  Y+ERYP IK Y+ENV
Sbjct  698  AADVTANDRRNAKAVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENV  757

Query  745  VKEAQEKGYVLTILNRRRFIPEIKASNKIVKALGDRLAMNAPIQGSAADIIKLAMVNVYN  804
            V+EA++KGYV T+++RRR +P+I++ N  V+++++R A+N+PIQGSAADI+K+AM+N+ +
Sbjct  758  VREAKDKGYVETLFKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDK  817

Query  805  KLNEKNLKSELILQVHDELILNvkkeefeevkklvaeeMENAIKLKVALDVDVNFGKTWY  864
             L+   +++ ++LQVHDE++L+V ++E+  +KKLV + ME A+ L V+L VD + G++WY
Sbjct  818  ALQAGGFRAKMLLQVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWY  877

Query  865  DAK  867
            +AK
Sbjct  878  EAK  880

480) Desdi_1602 in NC_019903


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  514 bits (1938),  Expect = 1e-146, Method: Compositional matrix adjust.
 Identities = 367/900 (41%), Positives = 565/900 (63%), Gaps = 61/900 (6%)

Query  2    SKILILDGNSLANRAFYAL----PVMTTADGKPTNVLHGFMTMLLRLLLEQKPDYWVVAF  57
            +K+L++DG+S+A RAF+AL           G  TN + GF  ML +++   +P   +VAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  58   DKTKATVRIEQYAEYKAQRKETPEALKPQFDFLKELLTDFSMPILECADYEADDIIATVT  117
            D  K+T R E YA+YKA R  TP+ ++ QF +++E+LT ++++  E  +YEADDII+T+ 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  118  SMAEKRE--WEVQIYTGDRDALQLVSPYTTVYLTRKGISEVDAYTEAALYEKYQLSPAQI  175
             MAE+ E   +V I +GD+D +QL    T V +++KG++E + +T A L EK  L+P Q+
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  176  IDLKGLMGDASDNIPGVPGVGEKTALKLLWEYASVENVLENIEKISGKKLQENLRNNTDK  235
            IDLK+LMGD SDNIPGV  +GEKT+LKLL E++S+E + E+I+ +   K++ENL N+ D+
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRDQ  244

Query  236  AILSKKLATMIYDVPLEIDLDKFAYRRPDEKIFAAALDKYVLKSVTRIWQEHHGVGVENN  295
            A+LSK LAT+    P+ I+LD + Y  PD            + S++++ +E + V + + 
Sbjct  245  AFLSKTLATINTASPITIGLDDIVYNGPD------------VASLSQFYDEMDFVQLKKG  292

Query  296  STAQ--ESTFEPWPLQELTTEEWVLHLQKWNNEKTPLTLAYANTEGNSHWANITG--WGI  351
             ++Q  +      + QE+T     L     + E     + +    +N H+  I G  WG 
Sbjct  293  LASQMPQEPVAVISYQEVTNVSADL----FSAEDI---FYFETLRDNYHREAIIGFAWG-  344

Query  352  AVAGESFTLAWTEVDLEVRRAFINLLEDPDVPKLVEDSKLLYTLLLNEEITMQGVAMDIS  411
              + + +  A T++ L    +F ++++ P        SK+L + L    I + + + D  
Sbjct  345  -HGEQIY--ASTDLSLLATDSFKQVFQKPIATYDFKRSKVLLSHL---GIELVAPSYDAR  398

Query  412  LAAYLINPTRSK--------FKSLELVKE---YIPGVTG--------FENLGEEASALAQ  452
            LA YL++    +        F  + L  +   Y  G           +E+L+     L +
Sbjct  399  LANYLLSTVEDNELSTIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLD  458

Query  453  VVGSYKETLEELGLNALLHEMEEPLSPILAQMEKQGIAVDVPMLEEFGQNLSGELKRLEE  512
              +   + L       L +++E PL+ +LA+ME +GI V+ + L++ +++    +  L +
Sbjct  459  SKSQMLDKLTAHEQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQ  518

Query  513  EIYKDAGETFNINSPQQLGHILFEKLGLP--PMKKTKTGYSTDADTLEELRTSHPMVEKI  570
            EIY  AG+ FNINSP+QLG ILFEK+ LP    KKTKTGYST  D LE L    P+V KI
Sbjct  519  EIYDMAGQEFNINSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKI  578

Query  571  LDYRQLSKLMSTYVNGLLAQI-REGRVHTTFQQTVAATGRLSSTEPNLQNIPIRLELGRL  629
            LDYRQ++KL STYV GL   I  +G++HT + Q ++ TGRLSS +PNLQNIPIRLE GRL
Sbjct  579  LDYRQITKLQSTYVIGLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRL  638

Query  630  LRKVFKPTQEGWVLLSADYSQIELRILAHYSQDEVMSESFFLNQDVHTRTASEVFGVPME  689
            +RK F P++E+ VLLS+DYSQIELR+LAH S DE +  +F    D+HT TA  VFG+   
Sbjct  639  IRKAFTPSHEDAVLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKA  698

Query  690  -EVTKDMRRKAKAVNFGLVYGLTEFGLGRDLGVPRKEAKDYIEKYFHRYEGVKRYLEEIV  748
             +VT + RR+AKAVNFG+VYG+++FGL+ +LG+ RK++K YI+ YF+RY G+K Y+E++V
Sbjct  699  ADVTANDRRNAKAVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVV  758

Query  749  VKAKEEAQVRTLLNRLRRIPELRHPNRVQRQFGERIAMNTPIQGTAADIMKLAMLGVAQA  808
              AK+ + V TL++R R +P++   N   R F+ER A+N+PIQG+AADI+K+AM+ + +A
Sbjct  759  REAKDKGYVETLFKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKA  818

Query  809  IEP--YRAHLLLQVHDELVIEVAPEELEVVAKIVREEMENAFPLSVPLTVECKSGPNWYD  866
            +++  +RA +LLQVHDE+V+EV+ +EL  + K+V++ ME A  L+VPL V+  +G +WY+
Sbjct  819  LQAGGFRAKMLLQVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYE  878

481) Clo1100_2472 in NC_016791


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  513 bits (1936),  Expect = 2e-146, Method: Compositional matrix adjust.
 Identities = 365/907 (41%), Positives = 586/907 (65%), Gaps = 38/907 (4%)

Query  1    MNSEDKILVVDGNSILNRAFYGL-SRAAMLTTSEGLYTNAVFGFINILSKYLQDENPKYV  59
            M++ +K+L++DG+S+  RAF++L ++   +    GL TNA++GF  +L   ++   P  V
Sbjct  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60

Query  60   CVAFDLKAPTFRHKEYDQYKAQRKGMPNELAVQVPIIKQVLDAMNIARVEVEGFEADDIL  119
             VAFD    TFR   Y +YKA R   P+E+  Q + I+++L A+ IA  E+E +EADDI+
Sbjct  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120

Query  120  GTVSLNAEKQGM--ETILLTGDRDSLQLASSHTRIKLPVTRGNKTETDQYDYEKVIEKYG  177
            GT+   AE+  +  +  +++GD+D +QL+  +T +   +++   +E +++    ++EK G
Sbjct  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVE--ISKKGVAEFEEFTPAYLMEKMG  178

Query  178  VTPGQLIDVKGLMGDTSDNIPGVPGIGEKTAIDLINKFNSLEELYENLDKVEKKGVREKL  237
            +TP Q+ID+K+LMGD SDNIPGV  IGEKT++ L++ F SLE +YE++D      ++E+L
Sbjct  179  LTPNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENL  238

Query  238  ENNKELAFMSKRLATIYRKVPGVENLSSFARTEIDKEALYGIFKRLEFKTLIEKFGLENT  297
             N+++ AF+SK LATI    P    L  +     D  +L  ++  ++F  L  K GL + 
Sbjct  239  INDRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQL--KKGLAS-  295

Query  298  PFVEATEALKIEHVDVDSISELQSYISVIKLSGNV----SVYYHVDPTGSYLDDLCI-FA  352
                        ++  ++++ + SY  V ++S+++     ++Y     ++Y  +  I FA
Sbjct  296  ------------QMPQEPVAVI-SYQEVTNVSADLFSAEDIFYFETLRDNYHREAIIGFA  342

Query  353  CNEEYAPANIIFSEKLTCETAVKELREIFESKDIEKYGHDLKNLYKYLKSSGIELENVVF  412
                 + ++ I++       A   ++++F+ K I  Y  D+K     L   GIEL    +
Sbjct  343  ----WGHGEQIYASTDLSLLATDSFKQVFQ-KPIATY--DFKRSKVLLSHLGIELVAPSY  395

Query  413  DTFIAAYILEPTRSTYTISELSEDKLKQSITPVEVLYDKHGKRLDQEQDISSSEVCAAAV  472
            D+ +A Y+L        +S ++      S+   + +Y+K +KR   ++D+   ++ A  V
Sbjct  396  DARLANYLLSTVEDN-ELSTIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHL-ARKV  453

Query  473  NAIFGLTQKLRPIIRDNGQDELYYKIELPLVEVLADMELRGFKVDVEGLKAYSKEMDSRL  532
            + +++   ++   +  + Q +LY +IELPL +VLA ME+ G+KV+   L+  + +    +
Sbjct  454  KVLLDSKSQMLDKLTAHEQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVII  513

Query  533  VILENEIYMQAGETFNINSPKQLGVILFEKLGLP--VGKKTKTGYSTSAEVLEQLSYKHE  590
              L +EIY  AG+ FNINSPKQLG ILFEK+ LP  + KKTKTGYST+ +VLE+L+    
Sbjct  514  EALTQEIYDMAGQEFNINSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAP  573

Query  591  IVERILEYRQLMKLKSTYADGLLSVLEQDGKIHSNFNQTVTATGRISSTEPNLQNIPVKL  650
            IV +IL+YRQ+ KL+STY  GL   +  DGKIH+ + Q +T TGR+SS +PNLQNIP++L
Sbjct  574  IVAKILDYRQITKLQSTYVIGLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRL  633

Query  651  EMGRKIRKVFIPTNQDYVLLDADYSQIELRVLAHITDDPNMIEAFLKNEDIHTTTASKVF  710
            E GR IRK F P+++D VLL +DYSQIELRVLAHI++D ++I AF    DIHT+TA +VF
Sbjct  634  EQGRLIRKAFTPSHEDAVLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVF  693

Query  711  GIP-PEEVSSLMRSRAKAVNFGIVYGIGDFSLSKDIGVTKKEARQYIDDYLDKYSKVKEY  769
            GI  + +V++  R  AKAVNFGIVYGI+DF+LS+++G+T+K+++ YID Y+++Y+ +K Y
Sbjct  694  GIDKAADVTANDRRNAKAVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAY  753

Query  770  MSDTVEKGKEFGFVTTLYSRRRYLPELKSSNFNMRSFGERVAMNTPIQGSAADIIKISMV  829
            M + V  +K+ G+V TL+ RRR LP+++S NFN+RSF+ER A+N+PIQGSAADI+KI+M+
Sbjct  754  MENVVREAKDKGYVETLFKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMI  813

Query  830  KVYNElkkrklksklilQVHDELIVETEKSELEEVSKVLKDCMENAVQLKVPLTVDVKHG  889
            ++ + L+   +++K++LQVHDE+++E  + EL  + K++KD ME AV+L VPL VD   G
Sbjct  814  NLDKALQAGGFRAKMLLQVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTG  873

Query  890  DSWYETK  896
            +SWYE+K
Sbjct  874  QSWYEAK  880

482) CC1_18790 in NC_021009


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  512 bits (1930),  Expect = 5e-146, Method: Compositional matrix adjust.
 Identities = 366/901 (41%), Positives = 574/901 (64%), Gaps = 50/901 (5%)

Query  2    SKVILIDGHSILNRAYYG----IPLLSNAEGLHTNAVYGFLNIMFKILDEEKADYLAVAF  57
            +K++LIDG S+  RA+++    I  + N  GLHTNA+YGF  ++  ++   ++  + VAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  58   DVHAPTFRHEMFEAYKGTRKPMPEELREQVPVIKEVLHAMQIPTLEHAGYEADDILGTLG  117
            D    TFR EM+  YK+ R   P+E+REQ + I+E+L A+ I+  E   YEADDI+GTL+
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  118  KAYE--AAGYAVSIISGDRDLLQLATDKIKIRIPKTKMSGTEIEDYYAADVFEKYQVTPT  175
            K  E     + V+I+SGD+DL+QL+ ++  + I  +K + +E+E++ +A + EK  +TP 
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEI--SKKGVAEFEEFTPAYLMEKMGLTPN  182

Query  176  EFIDMKALMGDTSDNIPGVPGIGEKTASKIISTWHSIeeahahaaeLKPKKASENLVTYY  235
            +FID+KALMGD SDNIPGV  IGEKT+ K++    S+E    H   +K  K  ENL+   
Sbjct  183  QFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDR  242

Query  236  EQAQFSKVLATIKTDCVLDFKLED--------AAIGQMMNDASYALLKRLELKNILKRFD  287
            +QA +SK LATI+T   + + L+D        A+++Q  ++  +  LK    K +  +  
Sbjct  243  DQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLK----KGLASQMP  298

Query  288  SVAETTVNYQTVKVLDD--FAAAVSWLEGIGETDQLGLYYFSE--DDF--EGLAACK-AD  340
              + + ++YQ V  +    F+A              +++YF    D++  E++ +   ++
Sbjct  299  QEPVAVISYQEVTNVSADLFSAE-------------DIFYFETLRDNYHREAIIGFAWGH  345

Query  341  NVPVYIPAEGMMTaavlremaaaaakraGVCCMIDVKPQLYWLELSEEDGIFDAAIAAYL  400
               +Y +++  ++            K  +       K  L  L +      +DA +A YL
Sbjct  346  GEQIYASTD--LSLLATDSFKQVFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYL  403

Query  401  INPLKDSYTYDGIAQDFLGMTVPSRADWLKKMTLTEASEKEKESFGHYLAYSAMIPVQAY  460
            ++ + D+     IA+ F ++++        K +    ++K+   + + LA    + +++ 
Sbjct  404  LSTVEDN-ELSTIARIFTDISLEEDDTVYGKGAKRAVPDKD--VLLEHLARKVKVLLDSK  460

Query  461  STLKKRLEETGMDRLFDEIEMPLVYALYDMEKAGIAVEKDALAEYGSRLTGRIDELEKNI  520
            S +  +L       L+++IE+PL   L  ME  GI V++ +L + + +    I+ L ++I
Sbjct  461  SQMLDKLTAHEQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEI  520

Query  521  YELAGESFNINSPKQLGIILFEKLGLPF--AKKTKTGYSTSADILEKLRTYDPIVGQILE  578
            Y++AG+ FNINSPKQLG ILFEK+ LP+  +KKTKTGYST+ D+LE+L    PIV++IL+
Sbjct  521  YDMAGQEFNINSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILD  580

Query  579  YRQLTKLKSTYADGLAGYIRPDDQRIHGKFNQTITATGRISSTEPNLQNIPVRMELGRLI  638
            YRQ+TKL+STY  GL +YI +D+ +IH ++ Q +T TGR+SS +PNLQNIP+R+E GRLI
Sbjct  581  YRQITKLQSTYVIGLQDYILADG-KIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLI  639

Query  639  RKVFVPK-EDCIFVNADYSQIELRVLAHMAGDEHLIQAYKEAQDIHRMTASQVFHTP-FD  696
            RK F P  ED +++++DYSQIELRVLAH++GDEHLI A++E+ DIH  TA +VF      
Sbjct  640  RKAFTPSHEDAVLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAA  699

Query  697  EVTPAQRSNAKAVNFGIVYGISSFGLSQDLSITKKEAENYIQQYFRTYPGIKAFLDRSVE  756
            +VT+ +R NAKAVNFGIVYGIS FGLS++L+IT+K++ +YI+ YF  YPGIKA+++  V 
Sbjct  700  DVTANDRRNAKAVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVR  759

Query  757  DAKEKGYAVTLFGRRRPVPELLSSNFMQRSFGERIAMNSPIQGTAADIIKIAMVRVNRRL  816
            +AK+KGY  TLF RRR +P++ S NF  RSF+ER A+NSPIQG+AADI+KIAM+ +++ L
Sbjct  760  EAKDKGYVETLFKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKAL  819

Query  817  KRQHMKSRLILQIHDELLIEAVLDEVDAVKAILKEEMEHAATLAVPLEIDMHTGHNWYEL  876
            +    +++++LQ+HDE+++E   DE+ A+K ++K+ ME A  LAVPL +D  TG++WYE 
Sbjct  820  QAGGFRAKMLLQVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEA  879

Query  877  K  877
            K
Sbjct  880  K  880

483) Tthe_1101 in NC_014410


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  508 bits (1918),  Expect = 5e-145, Method: Compositional matrix adjust.
 Identities = 373/892 (42%), Positives = 585/892 (66%), Gaps = 42/892 (4%)

Query  2    SKFLIIDGNSLMYRAYFAL----PDLMNSEGLHTNAIYGFSMMLLKLLDEEKPDYIAVAF  57
            +K+L+IDG+S+ +RA+FAL      + N  GLHTNAIYGF +ML  ++   +P  + VAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  58   DKKAPTFRHKEYSAYKGTRQSMPEELIEQVDILKDVINAFNIKTIEIEGFEADDIIGTVS  117
            D    TFR   Y+ YK+ R   P+E+ EQ   +++++ A+ I   E+E +EADDIIGT+ 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  118  KIA--SENGLKVLIVTGDRDALQLVSDGVKVKICKKGITQMEEYDERAVVERYEVTPRQF  175
            K+A  +E  + V IV+GD+D +QL  +   V I KKG+++ EE+    ++E+  +TP QF
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  176  IDLKGLMGDKSDNIPGVPNIGEKTAIKLIKEFGSIENVLMNTDKLK-GKIRENIENNTEM  234
            IDLK+LMGDKSDNIPGV +IGEKT++KL+ EFGS+E +  + D +K +K++EN+ N+ + 
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRDQ  244

Query  235  AMLSKKLATIERNVPIEIDLSEYQLRDYDREKLIDLFEKLEFTSLINDLKKDADDIREVK  294
            A LSK LATI+   PI I+L +    + D   L ++++ ++F     +LKK+     ++ 
Sbjct  245  AFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFV----QLKKGLAS--QMP  298

Query  295  EWPVRDFKY------IRELLKREDTLSFYPLILEGE---VKAVSFA-TDDESFFVEVDDY  344
            + PV  + Y        +L+  ED   FY   L ++      ++FA  ++E ++   D  
Sbjct  299  QEPVAVISYQEVTNVSADLFSAEDI--FYFETLRDNYHREAIIGFAWGHGEQIYASTD--  354

Query  345  EVFKLLDNEKL------TLIGHDIKDFFVNLSYHGIELNCKFYDTAIMTYLLNPSESNYD  398
              + LL  + +       +   D+K   V LS  GIEL    YD+ +  YLL+  E N +
Sbjct  355  --LSLLATDSFKQVFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDN-E  411

Query  399  IGRVLKKYLKEDIPNIEDMlgkgkskksyddidkkllidylCATAsklsklkdklmsFIK  458
            ++ + + +   DI+  ED    GK+ K        LL +        L    + L  +  
Sbjct  412  LSTIARIF--TDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTA  469

Query  459  EMEMEELLDNVELPLVEVLKSMEVYGFTLDKDVLKDLSKEIGEKTDKIIKDIYDAAGYEF  518
            + +++ L +N+ELPL +VL  ME+ G+ +++  L+D++ +     + + ++IYD AG EF
Sbjct  470  HEQLD-LYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEF  528

Query  519  NINSTKQLSEFLFDKLNLP--PIKKTKTGYSTDMEVLVELIPYNEIVGEIIEYRQLMKLK  576
            NINS KQL+ +LF+K++LP    KKTKTGYST ++VL  L P   IV+ I++YRQ+ KL+
Sbjct  529  NINSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQ  588

Query  577  STYIDGFMPIMDKDDKVHSTFKQTVAATGRISSTEPNLQNIPVRDEFGRRIRKAFISSFQ  636
            STY+ G+   +  D+K+H+ + Q ++ TGR+SS +PNLQNIP+R E GR IRKAF +S +
Sbjct  589  STYVIGLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHE  648

Query  637  GGYIVSADYSQIELRVLAHLSEDIKLIESFLNNEDIHLRTASEVFKIA-PEEVTGEMRRR  695
            ++ ++S+DYSQIELRVLAH+S D  LI +F +  DIH  TA  VF I  + +VT++ RR 
Sbjct  649  DAVLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRN  708

Query  696  AKAVNFGIVYGISDYGLSRDLKISRKEAKEYIDNYFDRYKGVKNYIDSVVKFARENGYVT  755
            AKAVNFGIVYGISD+GLS +L I+RK++K YID YF+RY G+K Y+++VV+ A+++GYV 
Sbjct  709  AKAVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVE  768

Query  756  TILNRRRYIPEINSKNYNQRSFGERMAMNTPIQGSAADIIKMSMVKVYNElksrslkskl  815
            T+++RRR +P+INS+N+N RSF+ER A+N+PIQGSAADI+K++M+++ + L++ ++++K+
Sbjct  769  TLFKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKM  828

Query  816  ILQIHDELIVDTFPDEVEIVKNLLKTIMENVIKLRVPLVVDIGYGKNWYDAK  867
            +LQ+HDE++++   DE+  +K+L+K  ME  + L VPL VD + G++WY+AK
Sbjct  829  LLQVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

484) Thet_0779 in NC_014538


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  507 bits (1913),  Expect = 1e-144, Method: Compositional matrix adjust.
 Identities = 365/892 (41%), Positives = 582/892 (66%), Gaps = 37/892 (4%)

Query  2    SKFLVIDGSSLMYRAYYAL----PMLTTSEGLHTNALYGFTMMLIKLIEEEKPDYIAIAF  57
            +K+L+IDGSS+ +RA++AL      +    GLHTNA+YGF +ML  ++   +P  + +AF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  58   DKKAPTFRHKEYQDYKATRQAMPEELAEQVDLLKEIIEGFNIKILELEGYEADDIIGTIS  117
            D    TFR   Y DYKA R   P+E+ EQ   ++E++ ++ I   ELE YEADDIIGT+ 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  118  KLAEEKEM--EVLVVTGDRDALQLvsdkvkvkiskkGITQMEEFDEKAVLERYEITPHQF  175
            K+AE  E+  +V +V+GD+D +QL  ++  V ISKKG+++ EEF    ++E+  +TP+QF
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  176  IDLKGLMGDKSDNIPGIPNIGEKTAIKLLKDFGTIENLLQNLSQLKGkikeni-ennkeL  234
            IDLK+LMGDKSDNIPG+ +IGEKT++KLL +FG++E + +++  +K     +   N+++ 
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRDQ  244

Query  235  AIMSKKLVTIKRDIPIEIDFEEYRVKEFNEEKLLEIFNKLEFFSL---IDSIKKKNDVEI  291
            A++SK L TI+   PI I++++   +  +   L ++++ ++F  L   + S   ++ V +
Sbjct  245  AFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEPVAV  304

Query  292  VNNHKVQKWSKVDIKKLIALLQDSKSIAFYPLI---YEGEIKKIAFSFGN-DTVYIDGFQ  347
            ++ +        ++ ++ A L  +  I ++  +   Y+ E   I+F+ G+ + +Y     
Sbjct  305  ISYQ--------EVTNVSADLFSAEDIFYFETLRDNYHREAI-IGFAWGHGEQIYAST--  353

Query  348  ikdlkeifekekfefttheikDFL---VKLSYKGIE-CKSKYMDTAIMAYLLNPSESNYD  403
               L       +         DF    V LS  GIE   + Y D+ +  YLL+  E N +
Sbjct  354  DLSLLATDSFKQVFQKPIATYDFKRSKVLLSHLGIELVAPSY-DARLANYLLSTVEDN-E  411

Query  404  LDRVLKKYLKVDVPSYEEVFGKGRDKKKLEEIGEDILADYICSRCVHLFDLREKLMNFIE  463
            L  + + +  + +   + V+GKG  K+ + +   D+L + +  +   L+D + ++++ + 
Sbjct  412  LSTIARIFTDISLEEDDTVYGKG-AKRAVPD--KDVLLEHLARKVKVLLDSKSQMLDKLT  468

Query  464  EMDMKRLLLEIEMPLVEVLKSMEVSGFTLDKEVLKELSQKINDRIAEILDKIYKEAGYQF  523
              +   L  +IE+PL +VL  ME+ G+ +++  L++++++ +  I  + + IY  AG +F
Sbjct  469  AHEQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEF  528

Query  524  NVNSPKQLSEFLFEKLNLP--VIKKTKTGYSTDSEVLEQLVPYNNIVNDIIEYRQLTKLK  581
            N+NSPKQL+ +LFEK++LP  + KKTKTGYST  +VLE+L P   IV  I++YRQ+TKL+
Sbjct  529  NINSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQ  588

Query  582  STYIDGFLPLMDENNRVHSNFKQMVTSTGRISSTEPNLQNIPIREEFGRQIRRAFIPRTK  641
            STY+ G+   +  + ++H+ + Q +T TGR+SS +PNLQNIPIR E GR IR+AF P   
Sbjct  589  STYVIGLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHE  648

Query  642  DGYIVSADYSQIELRVLAHVSGDEKLIESFMNNEDIHLRTASEVFKVPME-KVTPEMRRV  700
            D+ ++S+DYSQIELRVLAH+SGDE LI +F +  DIH  TA  VF +     VT++ RR 
Sbjct  649  DAVLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRN  708

Query  701  AKAVNFGIIYGISDYGLSRDLKISRKEAKEYINNYFERYKGVKEYIEKIVRFAKENGYVI  760
            AKAVNFGI+YGISD+GLS +L I+RK++K YI+ YFERY G+K Y+E++VR AK++GYV 
Sbjct  709  AKAVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVE  768

Query  761  TIMNRRRYIPEINSRNFTQRSQAERLAMNAPIQGSAADIIKMAMVRVYNDleklklkskl  820
            T+ +RRR +P+INSRNF  RS AER A+N+PIQGSAADI+K+AM+ + + L+   +++K+
Sbjct  769  TLFKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKM  828

Query  821  ilQVHDELVVDTYKDEVEIVKKILKDNMENVVQLKVPLVVEIGVGPNWFLAK  872
            +LQVHDE+V++  +DE+  +KK++KD ME  V+L VPL V+ + G +W+ AK
Sbjct  829  LLQVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

485) Teth514_2156 in NC_010320


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  507 bits (1913),  Expect = 1e-144, Method: Compositional matrix adjust.
 Identities = 365/892 (41%), Positives = 582/892 (66%), Gaps = 37/892 (4%)

Query  2    SKFLVIDGSSLMYRAYYAL----PMLTTSEGLHTNALYGFTMMLIKLIEEEKPDYIAIAF  57
            +K+L+IDGSS+ +RA++AL      +    GLHTNA+YGF +ML  ++   +P  + +AF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  58   DKKAPTFRHKEYQDYKATRQAMPEELAEQVDLLKEIIEGFNIKILELEGYEADDIIGTIS  117
            D    TFR   Y DYKA R   P+E+ EQ   ++E++ ++ I   ELE YEADDIIGT+ 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  118  KLAEEKEM--EVLVVTGDRDALQLvsdkvkvkiskkGITQMEEFDEKAVLERYEITPHQF  175
            K+AE  E+  +V +V+GD+D +QL  ++  V ISKKG+++ EEF    ++E+  +TP+QF
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  176  IDLKGLMGDKSDNIPGIPNIGEKTAIKLLKDFGTIENLLQNLSQLKGkikeni-ennkeL  234
            IDLK+LMGDKSDNIPG+ +IGEKT++KLL +FG++E + +++  +K     +   N+++ 
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRDQ  244

Query  235  AIMSKKLVTIKRDIPIEIDFEEYRVKEFNEEKLLEIFNKLEFFSL---IDSIKKKNDVEI  291
            A++SK L TI+   PI I++++   +  +   L ++++ ++F  L   + S   ++ V +
Sbjct  245  AFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEPVAV  304

Query  292  VNNHKVQKWSKVDIKKLIALLQDSKSIAFYPLI---YEGEIKKIAFSFGN-DTVYIDGFQ  347
            ++ +        ++ ++ A L  +  I ++  +   Y+ E   I+F+ G+ + +Y     
Sbjct  305  ISYQ--------EVTNVSADLFSAEDIFYFETLRDNYHREAI-IGFAWGHGEQIYAST--  353

Query  348  ikdlkeifekekfefttheikDFL---VKLSYKGIE-CKSKYMDTAIMAYLLNPSESNYD  403
               L       +         DF    V LS  GIE   + Y D+ +  YLL+  E N +
Sbjct  354  DLSLLATDSFKQVFQKPIATYDFKRSKVLLSHLGIELVAPSY-DARLANYLLSTVEDN-E  411

Query  404  LDRVLKKYLKVDVPSYEEVFGKGRDKKKLEEIGEDILADYICSRCVHLFDLREKLMNFIE  463
            L  + + +  + +   + V+GKG  K+ + +   D+L + +  +   L+D + ++++ + 
Sbjct  412  LSTIARIFTDISLEEDDTVYGKG-AKRAVPD--KDVLLEHLARKVKVLLDSKSQMLDKLT  468

Query  464  EMDMKRLLLEIEMPLVEVLKSMEVSGFTLDKEVLKELSQKINDRIAEILDKIYKEAGYQF  523
              +   L  +IE+PL +VL  ME+ G+ +++  L++++++ +  I  + + IY  AG +F
Sbjct  469  AHEQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEF  528

Query  524  NVNSPKQLSEFLFEKLNLP--VIKKTKTGYSTDSEVLEQLVPYNNIVNDIIEYRQLTKLK  581
            N+NSPKQL+ +LFEK++LP  + KKTKTGYST  +VLE+L P   IV  I++YRQ+TKL+
Sbjct  529  NINSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQ  588

Query  582  STYIDGFLPLMDENNRVHSNFKQMVTSTGRISSTEPNLQNIPIREEFGRQIRRAFIPRTK  641
            STY+ G+   +  + ++H+ + Q +T TGR+SS +PNLQNIPIR E GR IR+AF P   
Sbjct  589  STYVIGLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHE  648

Query  642  DGYIVSADYSQIELRVLAHVSGDEKLIESFMNNEDIHLRTASEVFKVPME-KVTPEMRRV  700
            D+ ++S+DYSQIELRVLAH+SGDE LI +F +  DIH  TA  VF +     VT++ RR 
Sbjct  649  DAVLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRN  708

Query  701  AKAVNFGIIYGISDYGLSRDLKISRKEAKEYINNYFERYKGVKEYIEKIVRFAKENGYVI  760
            AKAVNFGI+YGISD+GLS +L I+RK++K YI+ YFERY G+K Y+E++VR AK++GYV 
Sbjct  709  AKAVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVE  768

Query  761  TIMNRRRYIPEINSRNFTQRSQAERLAMNAPIQGSAADIIKMAMVRVYNDleklklkskl  820
            T+ +RRR +P+INSRNF  RS AER A+N+PIQGSAADI+K+AM+ + + L+   +++K+
Sbjct  769  TLFKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKM  828

Query  821  ilQVHDELVVDTYKDEVEIVKKILKDNMENVVQLKVPLVVEIGVGPNWFLAK  872
            +LQVHDE+V++  +DE+  +KK++KD ME  V+L VPL V+ + G +W+ AK
Sbjct  829  LLQVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

486) polA in NC_007503


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  501 bits (1889),  Expect = 8e-143, Method: Compositional matrix adjust.
 Identities = 374/884 (43%), Positives = 585/884 (67%), Gaps = 62/884 (7%)

Query  2    GKVVLVDGNSLLHRAFFAL----PPLKTTKGEPTGAVYGFLTMLFRVIKDEKPEYLAVAF  57
             K++L+DG+S+  RAFFAL      +K   G  T A+YGF  ML +++K  +P  + VAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  58   DISRKTFRTEQFTAYKGHRKEAPDELVPQFALVREVLKVLNVPYIELDGYEADDIIGHLS  117
            D ++ TFRTE ++ YK+ R  +PDE+  QF+ +RE+L  L ++Y EL+ YEADDIIG L 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  118  RAFAGQGH---EVVIYTADRDMLQLVDEKTVVYLTKKGITELVKMDLAAILENYGLKPKQ  174
            +  A + +   +V I ++D+D++QL DE+TVV ++KKG++E+     A ++E+ GL P+Q
Sbjct  125  K-MAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQ  183

Query  175  LVDVKGLMGDPSDNIPGVPGIGEKTALDLIKTYGSVEEVLAHKDELK-PKLREKLAEHEN  233
            ++D+K+LMGD SDNIPGV  IGEKT+L L+  +GS+E +  H D +K +K++E+L ++ +
Sbjct  184  FIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRD  243

Query  234  LAKISKQLATILREIPLEISLEDLKVKEPNYEEVAKLFLRLEFKSFLKEIEPKIKKEYQE  293
             A +SK LATI    P+ I+L+D+  + P+   +++++  ++F  + K + +++ +E   
Sbjct  244  QAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEPVA  303

Query  294  GKDLVQVETVETEGQIAVVFS--DGFYV----DDGEKTKFYSLDRLNEIEEIFRNKKI--  345
                 +V  V ++     +FS  D FY     D+ ++  + ++ +  + E+I+ +  +  
Sbjct  304  VISYQEVTNVSAD-----LFSAEDIFYFETLRDNYHREAIIGFAW-GHGEQIYASTDLSL  357

Query  346  -ITDDAKGIYHVCLEK-------------GLTFPEVCFDARIAAYVLNPADQN--PGLKG  389
              TD  K +++  +               G+ +    +DAR+A Y+L+  ++N  + +  
Sbjct  358  LATDSFKQVFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLANYLLSTVEDNELSTIAR  417

Query  390  LYLKYDL----PVY---------------EDVSLNIRGLFYLKKEMMKKIFEQEQERLFY  430
            ++    L     VY               E+++ +++ L+  K +M+ K+  +EQ  L+ 
Sbjct  418  IFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQ  477

Query  431  EIELPLTPVLAQMEHTGIQVDREALKEMSLELGEQIEELIREIYVLAGEEFNLNSPRQLG  490
            +IELPL+ VLA+ME  GI+V+R +L++M+ +    IE L +EIY +AG+EFN+NSP+QLG
Sbjct  478  NIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLG  537

Query  491  VILFEKLGLP--VIKKTKTGYSTDAEVLEELLPFHEIIGKILNYRQLMKLKSTYTDGLMP  548
             ILFEK+ LP  + KKTKTGYST  +VLE L P+  I++KIL+YRQ+ KL+STY  GL  
Sbjct  538  SILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQD  597

Query  549  LINERTGKLHTTFNQTGTLTGRLASSEPNLQNIPIRLELGRKLRKMFIPSPGYDYIVSAD  608
             I    GK+HT + Q  T TGRL+S +PNLQNIPIRLE GR +RK F PS     ++S+D
Sbjct  598  YILA-DGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSD  656

Query  609  YSQIELRLLAHFSEEPKLIEAYQKGEDIHRKTASEVFGVS-LEEVTPEMRAHAKSVNFGI  667
            YSQIELR+LAH+S +  LI A++ G DIH  TA  VFG+    +VT++ R +AK+VNFGI
Sbjct  657  YSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGI  716

Query  668  VYGISDFGLGRDLKIPREVAGKYIKNYFANYPKVREYLDELVRTAREKGYVTTLFGRRRY  727
            VYGISDFGL+ +L I R  +  YI  YF  YP ++ Y++++VR A++KGYV TLF RRR 
Sbjct  717  VYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRE  776

Query  728  IPELSSKNRTVQGFGERTAMNTPLQGSAADIIKLAMINVekelkarklksrlllsVHDel  787
            +P+++S+N  V++F+ERTA+N+P+QGSAADI+K+AMIN++K L+A  +++++LL VHDE+
Sbjct  777  LPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEI  836

Query  788  vlevpaeeleevkalvkGVMESVVELKVPLIAEVGAGKNWYEAK  831
            VLEVP +EL  +K LVK+ ME+ V+L VPL  + ++G++WYEAK
Sbjct  837  VLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

487) Cthe_0886 in NC_009012


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  498 bits (1877),  Expect = 8e-142, Method: Compositional matrix adjust.
 Identities = 368/902 (41%), Positives = 600/902 (67%), Gaps = 33/902 (3%)

Query  2    SKQKLMAIDGNSILNRAFYGL---PELLTTSDGIYTNGIYVFLNIMHKFIEEENPEYICV  58
            +K+KL+ IDG+S+  RAF++L    + +    G+ TN+IY F  +++  +    P  + V
Sbjct  3    NKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLV  62

Query  59   AFDLKAPTFRHNKYEGYKANRKGMPEELRVQVPLLKEVLDAMNIKRLEMEGFEADDILGS  118
            AFD    TFR + Y +YKA R   P+E+R Q + ++E+L A+ I   E+E +EADDI+G+
Sbjct  63   AFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGT  122

Query  119  VSLCAEKKGL--EVILVTGDRDAFQLIGPSTRLKLPRTRGGKTEVEEYDYNKIVEVYGIK  176
            +   AE+  +  +V +V+GD+D +QL + +T + +++   G +E EE+    ++E  G+ 
Sbjct  123  LDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKK--GVAEFEEFTPAYLMEKMGLT  180

Query  177  PEQFVDVKALAGDTSDNIPGVPGIGEKTALALIKeynnlenlynSLDSIKKKGLREKLET  236
            P+QF+D+KAL GD SDNIPGV  IGEKT+L L+ E+ +LE +Y+ +D++K   ++E+L  
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  237  FKEQAFLSRELALIERNMPSLCDIEELKRVEIDREKTYEIFKRLEFRSFIDKFGLNDVQI  296
             ++QAFLS+ LA I+   P   +++++     D     +++  ++F  +  K GL     
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQL--KKGLASQMP  298

Query  297  QNTVELNVKIAKNASELESLKNNILKSRKVCIYHLIDKTGSFSQKLAAIAISPVEDEAWY  356
            Q+ V +      +  E+ ++  +++ +  +  ++ +   +++ ++ A I+++  ++E  Y
Sbjct  299  QEPVAVI-----SYQEVTNVSADLFSAEDIFYFETL--RDNY-HREAIIGFAWGHGEQIY  350

Query  357  LDFTNNIDEDEFFRQFKDVLEDGNIKKYGHDLKNFIVYLNNRGIDFNGLAFDTMIGAYII  416
                 ++   +    FK+V++   I  Y  D+K   V L++ GI++ + ++D+ ++ Y++
Sbjct  351  ASTDLSLLATD---SFKQVFQKP-IATY--DFKRSKVLLSHLGIELVAPSYDARLANYLL  404

Query  417  NPSKETYTISELAQEYLNLSVKAVEELAGKGKSFTLF-KDMQPDVLSKTVGVYPHVISKV  475
            +   +   +S +A+ + ++S+   + + GKG   ++  KD+  + L++ V V   ++   
Sbjct  405  STVEDN-ELSTIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKV---LLDSK  460

Query  476  SRKIDSLLKENNQERLYYDIELPLVRTLADMEYYGFKVNVDALVEFSKELQEKIDVVTKE  535
            S+ +D L   ++Q  LY +IELPL   LA ME  G+KVN  +L + + + +  I+ +T+E
Sbjct  461  SQMLDKL-TAHEQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQE  519

Query  536  IYTLAGEEFNINSPKQLGVILFEKLGLPI--IKKTKTGYSTDAEVLEELSDRHEIVEKIL  593
            IY +AG+EFNINSPKQLG ILFEK+ LP+   KKTKTGYST  +VLE L+    IV KIL
Sbjct  520  IYDMAGQEFNINSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKIL  579

Query  594  EYRQLVKLKSTYAEGLLAVINPYTGKIHSSFNQTVTATGRISSTEPNLQNIPIKLEMGRK  653
            +YRQ+ KL+STY  GL   I +  GKIH+ + Q +T TGR+SS +PNLQNIPI+LE GR 
Sbjct  580  DYRQITKLQSTYVIGLQDYILA-DGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRL  638

Query  654  IRKVFIPSDENYLLLDADYSQIELRVLAHITNDENMINAFLNNEDIHTSTAASVFGIPKE  713
            IRK F PS+E+ +LL +DYSQIELRVLAHI+ DE++I AF +  DIHTSTA  VFGI K 
Sbjct  639  IRKAFTPSHEDAVLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKA  698

Query  714  -EVTPLMRSRAKAVNFGIVYGIGDFSLAKDLKISRKEARAYIDGYLDRYPNVKKYMHDIV  772
             +VT+  R  AKAVNFGIVYGI+DF+L+++L I+RK++++YID Y++RYP +K YM+++V
Sbjct  699  ADVTANDRRNAKAVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVV  758

Query  773  EEGKEKGFVTTMFMRRRYLPELKSRNFNIRSFGERVAMNTPIQGSAADIIKIAMVKVHGE  832
             E+K+KG+V T+F RRR LP+++SRNFN+RSF+ER A+N+PIQGSAADI+KIAM++++  
Sbjct  759  REAKDKGYVETLFKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKA  818

Query  833  lkkrklksrlilQVHDELIVETFKDEKEEVEKILLEGMQNAVSLKVPLVVEIKSGSNWYE  892
            L+   ++++++LQVHDE+++E  +DE   + K++ + M+ AV L VPL V+  +G +WYE
Sbjct  819  LQAGGFRAKMLLQVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYE  878

Query  893  TK  894
            +K
Sbjct  879  AK  880

488) Clo1313_1334 in NC_017304


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  498 bits (1877),  Expect = 8e-142, Method: Compositional matrix adjust.
 Identities = 368/902 (41%), Positives = 600/902 (67%), Gaps = 33/902 (3%)

Query  2    SKQKLMAIDGNSILNRAFYGL---PELLTTSDGIYTNGIYVFLNIMHKFIEEENPEYICV  58
            +K+KL+ IDG+S+  RAF++L    + +    G+ TN+IY F  +++  +    P  + V
Sbjct  3    NKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLV  62

Query  59   AFDLKAPTFRHNKYEGYKANRKGMPEELRVQVPLLKEVLDAMNIKRLEMEGFEADDILGS  118
            AFD    TFR + Y +YKA R   P+E+R Q + ++E+L A+ I   E+E +EADDI+G+
Sbjct  63   AFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGT  122

Query  119  VSLCAEKKGL--EVILVTGDRDAFQLIGPSTRLKLPRTRGGKTEVEEYDYNKIVEVYGIK  176
            +   AE+  +  +V +V+GD+D +QL + +T + +++   G +E EE+    ++E  G+ 
Sbjct  123  LDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKK--GVAEFEEFTPAYLMEKMGLT  180

Query  177  PEQFVDVKALAGDTSDNIPGVPGIGEKTALALIKeynnlenlynSLDSIKKKGLREKLET  236
            P+QF+D+KAL GD SDNIPGV  IGEKT+L L+ E+ +LE +Y+ +D++K   ++E+L  
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  237  FKEQAFLSRELALIERNMPSLCDIEELKRVEIDREKTYEIFKRLEFRSFIDKFGLNDVQI  296
             ++QAFLS+ LA I+   P   +++++     D     +++  ++F  +  K GL     
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQL--KKGLASQMP  298

Query  297  QNTVELNVKIAKNASELESLKNNILKSRKVCIYHLIDKTGSFSQKLAAIAISPVEDEAWY  356
            Q+ V +      +  E+ ++  +++ +  +  ++ +   +++ ++ A I+++  ++E  Y
Sbjct  299  QEPVAVI-----SYQEVTNVSADLFSAEDIFYFETL--RDNY-HREAIIGFAWGHGEQIY  350

Query  357  LDFTNNIDEDEFFRQFKDVLEDGNIKKYGHDLKNFIVYLNNRGIDFNGLAFDTMIGAYII  416
                 ++   +    FK+V++   I  Y  D+K   V L++ GI++ + ++D+ ++ Y++
Sbjct  351  ASTDLSLLATD---SFKQVFQKP-IATY--DFKRSKVLLSHLGIELVAPSYDARLANYLL  404

Query  417  NPSKETYTISELAQEYLNLSVKAVEELAGKGKSFTLF-KDMQPDVLSKTVGVYPHVISKV  475
            +   +   +S +A+ + ++S+   + + GKG   ++  KD+  + L++ V V   ++   
Sbjct  405  STVEDN-ELSTIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKV---LLDSK  460

Query  476  SRKIDSLLKENNQERLYYDIELPLVRTLADMEYYGFKVNVDALVEFSKELQEKIDVVTKE  535
            S+ +D L   ++Q  LY +IELPL   LA ME  G+KVN  +L + + + +  I+ +T+E
Sbjct  461  SQMLDKL-TAHEQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQE  519

Query  536  IYTLAGEEFNINSPKQLGVILFEKLGLPI--IKKTKTGYSTDAEVLEELSDRHEIVEKIL  593
            IY +AG+EFNINSPKQLG ILFEK+ LP+   KKTKTGYST  +VLE L+    IV KIL
Sbjct  520  IYDMAGQEFNINSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKIL  579

Query  594  EYRQLVKLKSTYAEGLLAVINPYTGKIHSSFNQTVTATGRISSTEPNLQNIPIKLEMGRK  653
            +YRQ+ KL+STY  GL   I +  GKIH+ + Q +T TGR+SS +PNLQNIPI+LE GR 
Sbjct  580  DYRQITKLQSTYVIGLQDYILA-DGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRL  638

Query  654  IRKVFIPSDENYLLLDADYSQIELRVLAHITNDENMINAFLNNEDIHTSTAASVFGIPKE  713
            IRK F PS+E+ +LL +DYSQIELRVLAHI+ DE++I AF +  DIHTSTA  VFGI K 
Sbjct  639  IRKAFTPSHEDAVLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKA  698

Query  714  -EVTPLMRSRAKAVNFGIVYGIGDFSLAKDLKISRKEARAYIDGYLDRYPNVKKYMHDIV  772
             +VT+  R  AKAVNFGIVYGI+DF+L+++L I+RK++++YID Y++RYP +K YM+++V
Sbjct  699  ADVTANDRRNAKAVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVV  758

Query  773  EEGKEKGFVTTMFMRRRYLPELKSRNFNIRSFGERVAMNTPIQGSAADIIKIAMVKVHGE  832
             E+K+KG+V T+F RRR LP+++SRNFN+RSF+ER A+N+PIQGSAADI+KIAM++++  
Sbjct  759  REAKDKGYVETLFKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKA  818

Query  833  lkkrklksrlilQVHDELIVETFKDEKEEVEKILLEGMQNAVSLKVPLVVEIKSGSNWYE  892
            L+   ++++++LQVHDE+++E  +DE   + K++ + M+ AV L VPL V+  +G +WYE
Sbjct  819  LQAGGFRAKMLLQVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYE  878

Query  893  TK  894
            +K
Sbjct  879  AK  880

489) polA in NC_016077


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  497 bits (1876),  Expect = 9e-142, Method: Compositional matrix adjust.
 Identities = 373/917 (41%), Positives = 589/917 (65%), Gaps = 85/917 (9%)

Query  2    NETFLIIDGSSLIHRAFFAL----PSFTNKKGVNTGAVYGLCNMLLKLLEEVKPSYMAVA  57
            ++ +L+IDGSS+  RAFFAL      F N  G++T A+YG+  ML  ++  V+P+ + VA
Sbjct  4    KNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVA  63

Query  58   FDKSRHSFRTEKFADYKGQRKATPPELKEQFPLAIELLTSMGIPTLEMDNYEADDLIGTL  117
            FD ++ +FRTE +ADYK+ R  TP E++EQF+   E+LT++GI+  E+++YEADD+IGTL
Sbjct  64   FDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTL  123

Query  118  SATAPKE---MKVIIVTGDRDEFQLIKENVHVYFTKKGITQIGNYDEAAFQKEYEGLSPR  174
               A +      V IV+GD+D +QL  EN  V ++KKG++++ ++  +A+  E  GL+P 
Sbjct  124  DKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFT-PAYLMEKMGLTPN  182

Query  175  QIIDLKGLMGDTSDNIPGVPGVGPKTALKLIKEYQSVEAVLDHAEEVKGKSLKEKLITFR  234
            Q+IDLK+LMGD SDNIPGV  +G KT+LKL+ E+ S+E++ +H +  K   +KE+LI  R
Sbjct  183  QFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDR  242

Query  235  NQALLSKELATICLTVPMDT--DPASYRLTGLTEKSRVLMDDLQFKNMWNRFSPVLGLAD  292
            +QA+LSK LATI  + P+    D   Y   +++  S+ + D+++F ++ +      GLA 
Sbjct  243  DQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQ-FYDEMDFVQLKK------GLAS  295

Query  293  GVSKAQDGGEMSMFGEV--IAEDAYETVPLASLEAATAFLTRVKEGSAPLSLMYETEGLL  350
             +  +Q+   +  + EV  ++ D + +           ++  +++        Y+ E+++
Sbjct  296  QM--PQEPVAVISYQEVTNVSADLFSA-------EDIFYFETLRDN-------YHREAII  339

Query  351  PHLTLTSLSGAHDHKVYVWDKallndanmlallCDGAIKKIVPNPKELYKFMQGK-----  405
                  +++ +H++++Y         +  L+LL  +++K++  +P   Y F ++K     
Sbjct  340  ------GFAWGHGEQIYA--------STDLSLLATDSFKQVFQKPIATYDFKRSKVLLSH  385

Query  406  -GVSLQGVIGDPSLAAYLYEPGETHYDVKSLAETYLPAS-------CGGTAQ----DVEA  453
             G+ L +   D+ LA YL    E + ++ ++A  +   S        G  A+    D + 
Sbjct  386  LGIELVAPSYDARLANYLLSTVEDN-ELSTIARIFTDISLEEDDTVYGKGAKRAVPDKDV  444

Query  454  LMPVLE----GLMAERG--LTELYRDIELPL--------TKVLANMEVNGITLDKGMLDE  499
            L+  L      L+  ++  L  L  + +L L        ++VLA+ME++GI ++++ L++
Sbjct  445  LLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNIELPLANVLAKMEIEGIKVNRATLQD  504

Query  500  VTKSMTKQVADLEQKAKEEAGEDFNVNSPKQLGVILFEKLGLPI--IKKTKSGYSTDVSV  557
            ++      +  L Q   + AG++FN+NSPKQLG ILFEK+ LP+   KKTK+GYST V V
Sbjct  505  MAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDV  564

Query  558  LEQLQGEHPIIETIMEYRTLSKLLSTYLVALHPLINPNTGRIHTHFNQMATVTGRLSSTD  617
            LE+L    PI+  I++YR ++KL STY+++L+  I ++ G+IHT++ Q  T TGRLSS D
Sbjct  565  LERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYILAD-GKIHTRYVQDLTQTGRLSSVD  623

Query  618  PNLQNIPTRTEVGKQMRRMFVPGKGYDLLMSCDYSQVELRVMASIAGDERLIDAFRHGQD  677
            PNLQNIP R E G+ +R+ F P+    +L+S DYSQ+ELRV+A I+GDE+LI AF +G D
Sbjct  624  PNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQIELRVLAHISGDEHLIAAFNEGAD  683

Query  678  IHSRTASEIFGVP-IEDVTPFMRSKAKTVNFGIIYGISDFGLGRQLGVPRSEAAQYIDSY  736
            IH+ TA  +FG+    DVT+  R +AK+VNFGI+YGISDFGL+ +LG+ R ++  YID+Y
Sbjct  684  IHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGISDFGLSNNLGITRKQSKSYIDTY  743

Query  737  FARYTGVKEYMEGEKKKAREMGYVETLFGRRRYLPDIHAKNFNRRSFAERTAINTPIQGT  796
            F RY G+K YME   + A++ GYVETLF RRR LPDI+++NFN RSFAERTAIN+PIQG+
Sbjct  744  FERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDINSRNFNVRSFAERTAINSPIQGS  803

Query  797  AADIIKIAMLHVAKELKEAGVKSRvllqvhdelvlevveeeKDKVSAIVKNAMERAVTLK  856
            AADI+KIAM+++ K L+ +G ++++LLQVHDE+VLEV ++E   +  +VK++ME AV L 
Sbjct  804  AADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLA  863

Query  857  VPLVADIAFGKTWADAK  873
            VPL  D + G++W +AK
Sbjct  864  VPLCVDESTGQSWYEAK  880

490) SFBM_0266 in NC_015913


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  495 bits (1868),  Expect = 4e-141, Method: Compositional matrix adjust.
 Identities = 361/892 (41%), Positives = 588/892 (66%), Gaps = 52/892 (5%)

Query  2    ERVLILDSNSILNRAFYAL----PLLSCSEGIHTNGILGYLTMFFKMQEEFNATYVIATF  57
            +++L++D++S+  RAF+AL      +    G+HTN+I G+  M+  M     +T V+ +F
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  58   DRKAKTFRHLEYSNYKSGRKSMPNELFEQLEPLKEILKAMNINIFELDGFEADDLIGTLS  117
            D    TFR   Y++YK+GR   P+E+ EQ+  ++E+L A+ I  +EL+ +EADD+IGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  118  RIYE--EEGFEPIIVTGDKDALQLsssitkviitkkgitDKEVYNEEKMIEVYGVTPTEF  175
            ++ E  E  F+  IV+GDKD +QL+   T V I+KKG+++ E +    ++E  G+TP +F
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  176  IDVKAIMGDKSDNIPGVSGIGEKGAISLIKEFKSIENLYENLECLKEGKIKKNLIEGMES  235
            ID+KA+MGDKSDNIPGV+ IGEK ++ L+ EF S+E +YE+++ +K +K+K NLI++ + 
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRDQ  244

Query  236  AFLSKKLSKINRFVPIDFSLNDMKVYSELDHLRVYELYNKYelksllnkinsnnesYEIL  295
            AFLSK L+ IN   PI ++L+D+ VY+  D   + ++Y+  ++  L + + S+     + 
Sbjct  245  AFLSKTLATINTASPITIGLDDI-VYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEPV-  302

Query  296  VNEISSTEDLTDLLNKIYNSNCNLYIYCDVLGNK-----VSEMHFGNMYINFNNENYILK  350
               + S +++T++   +++++ +++ Y + L ++     +     G+    + + +  L 
Sbjct  303  --AVISYQEVTNVSADLFSAE-DIF-YFETLRDNYHREAIIGFAWGHGEQIYASTDLSL-  357

Query  351  ENFICENFDDVSRIFSSKNDKICFDSKMIHKVMLIN-GKEVNNIIFDLVIGDYLLKPGRE  409
              +  ++F +V   F        F      KV+L + G E+    +D  +++YLL    +
Sbjct  358  --LATDSFKQV---FQKPIATYDFKRS---KVLLSHLGIELVAPSYDARLANYLLSTVED  409

Query  410  RTLISLCRDYVSVSLDEDDTCLAVS----------FFEDIYKTI----------LNKIDK  449
              L ++ R +  +SL+EDDT  + +          ++E++ + +          L+K+  
Sbjct  410  NELSTIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTA  469

Query  450  CNMRELYFEIEHLLSPILASIELEGFRVSVEMLGELKEKFDIKIKEHSEKIYSLSGEVFN  509
             +  +LY +IE  L+ +LA +E+EG++V+   L ++ E+  + I   ++ IY ++G+ FN
Sbjct  470  HEQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFN  529

Query  510  INSPKQLGKILFEKLDLP--VIRKTKTGYSTNAEVLEALMDKHEIIEEIVNYRQITKLQS  567
            INSPKQLG ILFEK++LP  + +KTKTGYST  +VLE L     I+  I++YRQITKLQS
Sbjct  530  INSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQS  589

Query  568  TYILGLMDVIDYDFKVHTSFNQTLTATGRLSSVDPNLQNIPIKYPLGREIRKAFIA-EKN  626
            TY++GL D I  D K+HT + Q LT TGRLSSVDPNLQNIPI+   GR IRKAF + + +
Sbjct  590  TYVIGLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHED  649

Query  627  SYILSADYSQIELRMLAHISEDDNIIKAFRENLDIHKMTASEIFSVD-EDDVTSEMRNKC  685
            + +LS+DYSQIELR+LAHIS D+++I AF E  DIH  TA  +F++D   DVT++ R + 
Sbjct  650  AVLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNA  709

Query  686  KAVNFGIIYGISDFALSNDLKISKKEAREYMDRYFNRYVGVKRYLDEIVVKAKKDGFVTT  745
            KAVNFGI+YGISDF+LSN+L I++K+++ Y+D YF+RY G+K Y++++V  AK  G+V T
Sbjct  710  KAVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVET  769

Query  746  IFNRRRDIPEIKSSNKIIRSLGERLAMNTPIQGSAADIIKLAMIKVYNRLNEENLKSKII  805
            +F+RRR++P+I+S N  +RS++ER A+N+PIQGSAADI+K+AMI++ + L+   +++K++
Sbjct  770  LFKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKML  829

Query  806  LQVHDELVLNVYEDEIDRVSLIVKEEMELCYDGILVPLSINLSYGKNWFEAK  857
            LQVHDE+VL+V +DE+  +  +VK+ ME   D + VPL ++ S G++W+EAK
Sbjct  830  LQVHDEIVLEVPNDELTAIKKLVKDTMEAAVD-LAVPLCVDESTGQSWYEAK  880

491) polA2 in NC_017294


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  495 bits (1868),  Expect = 4e-141, Method: Compositional matrix adjust.
 Identities = 361/892 (41%), Positives = 588/892 (66%), Gaps = 52/892 (5%)

Query  2    ERVLILDSNSILNRAFYAL----PLLSCSEGIHTNGILGYLTMFFKMQEEFNATYVIATF  57
            +++L++D++S+  RAF+AL      +    G+HTN+I G+  M+  M     +T V+ +F
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  58   DRKAKTFRHLEYSNYKSGRKSMPNELFEQLEPLKEILKAMNINIFELDGFEADDLIGTLS  117
            D    TFR   Y++YK+GR   P+E+ EQ+  ++E+L A+ I  +EL+ +EADD+IGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  118  RIYE--EEGFEPIIVTGDKDALQLsssitkviitkkgitDKEVYNEEKMIEVYGVTPTEF  175
            ++ E  E  F+  IV+GDKD +QL+   T V I+KKG+++ E +    ++E  G+TP +F
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  176  IDVKAIMGDKSDNIPGVSGIGEKGAISLIKEFKSIENLYENLECLKEGKIKKNLIEGMES  235
            ID+KA+MGDKSDNIPGV+ IGEK ++ L+ EF S+E +YE+++ +K +K+K NLI++ + 
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRDQ  244

Query  236  AFLSKKLSKINRFVPIDFSLNDMKVYSELDHLRVYELYNKYelksllnkinsnnesYEIL  295
            AFLSK L+ IN   PI ++L+D+ VY+  D   + ++Y+  ++  L + + S+     + 
Sbjct  245  AFLSKTLATINTASPITIGLDDI-VYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEPV-  302

Query  296  VNEISSTEDLTDLLNKIYNSNCNLYIYCDVLGNK-----VSEMHFGNMYINFNNENYILK  350
               + S +++T++   +++++ +++ Y + L ++     +     G+    + + +  L 
Sbjct  303  --AVISYQEVTNVSADLFSAE-DIF-YFETLRDNYHREAIIGFAWGHGEQIYASTDLSL-  357

Query  351  ENFICENFDDVSRIFSSKNDKICFDSKMIHKVMLIN-GKEVNNIIFDLVIGDYLLKPGRE  409
              +  ++F +V   F        F      KV+L + G E+    +D  +++YLL    +
Sbjct  358  --LATDSFKQV---FQKPIATYDFKRS---KVLLSHLGIELVAPSYDARLANYLLSTVED  409

Query  410  RTLISLCRDYVSVSLDEDDTCLAVS----------FFEDIYKTI----------LNKIDK  449
              L ++ R +  +SL+EDDT  + +          ++E++ + +          L+K+  
Sbjct  410  NELSTIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTA  469

Query  450  CNMRELYFEIEHLLSPILASIELEGFRVSVEMLGELKEKFDIKIKEHSEKIYSLSGEVFN  509
             +  +LY +IE  L+ +LA +E+EG++V+   L ++ E+  + I   ++ IY ++G+ FN
Sbjct  470  HEQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFN  529

Query  510  INSPKQLGKILFEKLDLP--VIRKTKTGYSTNAEVLEALMDKHEIIEEIVNYRQITKLQS  567
            INSPKQLG ILFEK++LP  + +KTKTGYST  +VLE L     I+  I++YRQITKLQS
Sbjct  530  INSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQS  589

Query  568  TYILGLMDVIDYDFKVHTSFNQTLTATGRLSSVDPNLQNIPIKYPLGREIRKAFIA-EKN  626
            TY++GL D I  D K+HT + Q LT TGRLSSVDPNLQNIPI+   GR IRKAF + + +
Sbjct  590  TYVIGLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHED  649

Query  627  SYILSADYSQIELRMLAHISEDDNIIKAFRENLDIHKMTASEIFSVD-EDDVTSEMRNKC  685
            + +LS+DYSQIELR+LAHIS D+++I AF E  DIH  TA  +F++D   DVT++ R + 
Sbjct  650  AVLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNA  709

Query  686  KAVNFGIIYGISDFALSNDLKISKKEAREYMDRYFNRYVGVKRYLDEIVVKAKKDGFVTT  745
            KAVNFGI+YGISDF+LSN+L I++K+++ Y+D YF+RY G+K Y++++V  AK  G+V T
Sbjct  710  KAVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVET  769

Query  746  IFNRRRDIPEIKSSNKIIRSLGERLAMNTPIQGSAADIIKLAMIKVYNRLNEENLKSKII  805
            +F+RRR++P+I+S N  +RS++ER A+N+PIQGSAADI+K+AMI++ + L+   +++K++
Sbjct  770  LFKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKML  829

Query  806  LQVHDELVLNVYEDEIDRVSLIVKEEMELCYDGILVPLSINLSYGKNWFEAK  857
            LQVHDE+VL+V +DE+  +  +VK+ ME   D + VPL ++ S G++W+EAK
Sbjct  830  LQVHDEIVLEVPNDELTAIKKLVKDTMEAAVD-LAVPLCVDESTGQSWYEAK  880

492) Ccel_2075 in NC_011898


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  492 bits (1857),  Expect = 3e-140, Method: Compositional matrix adjust.
 Identities = 369/903 (41%), Positives = 579/903 (65%), Gaps = 30/903 (3%)

Query  1    MNSEDKILVVDGNSILNRAFYGL-SRAAMLTTSEGLYTNAVFGFINILSKHLQDENPKYV  59
            M++ +K+L++DG+S+  RAF++L ++   +    GL TNA++GF  +L   ++   P  V
Sbjct  1    MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHV  60

Query  60   CVAFDLKAPTFRHKEYDQYKAQRKGMPNELAVQVPIIKQVLDAMNIARVEVEGFEADDIL  119
             VAFD    TFR   Y +YKA R   P+E+  Q + I+++L A+ IA  E+E +EADDI+
Sbjct  61   LVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDII  120

Query  120  GTVSSYAEKQGM--KTILLTGDRDSLQLASNYTRIKLPVTRANKTETDEYDYEKVIEKYG  177
            GT+   AE+  +     +++GD+D +QL+ + T +   +++   +E +E+    ++EK G
Sbjct  121  GTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVE--ISKKGVAEFEEFTPAYLMEKMG  178

Query  178  VTPGQLIDVKGLMGDTSDNIPGVPGIGEKTALALIKKFNSLEELYENIDKVDKKGVREKL  237
            +TP Q+ID+K+LMGD SDNIPGV  IGEKT+L L+  F SLE +YE+ID      ++E+L
Sbjct  179  LTPNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENL  238

Query  238  ENNKELAFMCKRLATIYRKVPGVENLNDFARLEIDKEKLYSIFKRLEFKTLIEKFGLENT  297
             N+++ AF+ K LATI    P    L+D+     D   L  ++  ++F  L  K GL + 
Sbjct  239  INDRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQL--KKGLASQ  296

Query  298  PFVEATEALKIEHVDVDSISELQSYISVIKLSGMVSVYYHVDPAGSYLDDLCI-FACNEE  356
               E+   +  +  +V ++S          L +   ++Y     ++Y  +  I FA    
Sbjct  297  MPQEPVAVISYQ--EVTNVSA--------DLFSAEDIFYFETLRDNYHREAIIGFA----  342

Query  357  YAPANIIFSEKLTCETVVNELREIFESKDIEKYGHDLKNLYKYLKSHGIELENVIFDTFI  416
             + ++ I++         + ++++F+ K I  Y  D+K     L   GIEL    +D+ +
Sbjct  343  WGHGEQIYASTDLSLLATDSFKQVFQ-KPIATY--DFKRSKVLLSHLGIELVAPSYDARL  399

Query  417  AAYILEPTRSTYTISELSEDKLKQSITPVEILYDKHGKRLEQGQDVSSSEVCAAAVNAIY  476
            A Y+L        +S ++      S+   + +Y+K +KR   ++DV   ++ A  V+ + 
Sbjct  400  ANYLLSTVEDN-ELSTIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHL-ARKVKVLL  457

Query  477  GLTQKLRPIIRDNGQDELYYKIELPLVEVLANMELRGFKVDVENLKAYSKELDSRLVILE  536
            +   ++   +  + Q +LY +IELPL +VLA+ME+ G+KV+   L+  + +    +  L 
Sbjct  458  DSKSQMLDKLTAHEQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALT  517

Query  537  NEIYMQAGETFNINSPKQLGVILFEKLGLP--VGKKTKTGYSTSAEVLEQLSYKHEIVER  594
            +EIY  AG+ FNINSPKQLG ILFEK+ LP  + KKTKTGYST+ +VLE+L+    IV +
Sbjct  518  QEIYDMAGQEFNINSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAK  577

Query  595  ILEYRQLMKLKSTYADGLLSVLEQDGKIHSNFNQTVTATGRISSTEPNLQNIPVKLEMGR  654
            IL+YRQ+ KL+STY  GL   +  DGKIH+ + Q +T TGR+SS +PNLQNIP++LE GR
Sbjct  578  ILDYRQITKLQSTYVIGLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGR  637

Query  655  KIRKVFIPTNSDYVLLDADYSQIELRVLAHITGDPNMIEAFINNEDIHTTTASKVFGIP-  713
             IRK F P++ D VLL +DYSQIELRVLAHI+GD ++I AF +  DIHT+TA +VFGI  
Sbjct  638  LIRKAFTPSHEDAVLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDK  697

Query  714  PEEVSSLMRSRAKAVNFGIVYGIGDFSLSKDIGVTKKEARKYIDDYLDKYSKVKEYMSDT  773
            + +V++  R  AKAVNFGIVYGI+DF+LS+++G+T+K+++ YID Y+++Y+ +K YM + 
Sbjct  698  AADVTANDRRNAKAVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENV  757

Query  774  VEKGKEFGFVTTLYNRRRYLPELKSSNFNMRSFGERVAMNTPIQGSAADIIKISMVKVYT  833
            V  +K+ G+V TL++RRR LP+++S NFN+RSF+ER A+N+PIQGSAADI+KI+M+++  
Sbjct  758  VREAKDKGYVETLFKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDK  817

Query  834  ElkkrklksklilQVHDelivetekseleevskllkDCMENAVQLKVPLTVDVKHGDSWY  893
             L+   +++K++LQVHDE+++E  + EL  + KL+KD ME AV+L VPL VD   G+SWY
Sbjct  818  ALQAGGFRAKMLLQVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWY  877

Query  894  DTK  896
            ++K
Sbjct  878  EAK  880

493) Calow_1220 in NC_014657


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  490 bits (1847),  Expect = 2e-139, Method: Compositional matrix adjust.
 Identities = 373/898 (42%), Positives = 570/898 (64%), Gaps = 72/898 (8%)

Query  2    KLVIFDGNSILYRAFFAL----PELTTSSNIPTNAIYGFINVILKYLEQESPDYVAVAFD  57
            KL+++DG+S+ +RAFFAL      +   S + TNAIYGF  ++   + +  P  V VAFD
Sbjct  6    KLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAFD  65

Query  58   KKGRQARKSEYEEYKANRKPMPDNLQVQIPYVREILYALNIPIIEFEGYEADDVIGSLVN  117
                  R   Y +YKA R   PD+++ Q++Y+RE+L AL I+  E+E YEADD+IG+L +
Sbjct  66   AGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLDK  125

Query  118  MF--KNIDLDIVIITGDKDTLQLLDKNVVVKIVSTKFDKTTEDLYTAENVKEKYGVWANQ  175
            M    ++ +D+ I++GDKD +QL D N VV I         E  +T+  + EK G+ +NQ
Sbjct  126  MAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEE--FTPAYLMEKMGLTPNQ  183

Query  176  VPDYKALVGDQSDNIPGVKGIGAKSAQKLLKEYSSLEEIYQNLDKIKGS-IREKLETGKD  234
              D KAL+GD+SDNIPGV  IG K++ KLL E++SLE IY+++D +K S ++E+L  ++D
Sbjct  184  FIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRD  243

Query  235  MAFLSKRLATIVCDLPLNVKLEDLRTKEWNKEKLYEILVQLEFKSIIKRLGLSEEVQFEF  294
             AFLSK LATI    P+ + L+D+  +  +   L ++  +++F  + K  GL+ ++  E 
Sbjct  244  QAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKK--GLASQMPQEP  301

Query  295  VQQLTNIHDVEQKKLESISQIRSKDISLMFVPEEKCFYL------YDKESNTVFV-TRER  347
            V  ++          + ++++ +     +F +E+  FY+      Y++E+   F   +  
Sbjct  302  VAVIS---------YQEVTNVSAD----LFSAED-IFYFETLRDNYHREAIIGFAWGHGE  347

Query  348  HLIEE----ILKSESVKIV-------YDLKN---MFHELYLENTDNIRNCEDVMIASYVL  393
            ++       +L ++S K V       YD+K    ++ +L     + +    D  +A+Y+L
Sbjct  348  QIYASTDLSLLATDSFKQVFQKPIATYDFKRSKVLLSHL---GIELVAPSYDARLANYLL  404

Query  394  DSTRSSYELETLFMSYLNTDLEA-----VKKDKKVTSV--ILLERLWDELSSLIDLNSCQ  446
             +   + EL T+   + +  LE       K  K+  +   +LLE+L   +  L+D +S  
Sbjct  405  STVEDN-ELSTIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQM  463

Query  447  F----------VYTNIERPLIPILYEMEKAGFKVDRDALLQYTKEIESKILNLEKQIYQI  496
            +          +Y NIE PL  +L  ME  G+KV+R +L + + +    I  L ++IY++
Sbjct  464  LDKLTAHEQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDM  523

Query  497  AGEWFNINSPKQLSYILFEKLKLP--VIKKTKTGYSTDAEVLEELFDKHEIVPLILDYRM  554
            AG+ FNINSPKQL+ ILFEK++LP  + KKTKTGYST  +VLE L     IV+ ILDYR 
Sbjct  524  AGQEFNINSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQ  583

Query  555  YTKILTTYCQGLLQAINPSSGRVHTTFIQTGTATGRLASSDPNLQNIPVKYDEGRLIRKV  614
             TK+ +TY  GL Q    + G++HT ++Q  T TGRL+S DPNLQNIP++ ++GRLIRK 
Sbjct  584  ITKLQSTYVIGL-QDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKA  642

Query  615  FIP-EEGHVLIDADYSQIELRILAHISEDERLINAFKNNVDIHSQTAAEIFGVD-IDDVT  672
            F P +E+ VL+ +DYSQIELR+LAHIS DE+LI AF++  DIH+ TA  +FG+D   DVT
Sbjct  643  FTPSHEDAVLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVT  702

Query  673  PEMRSQAKAVNFGIVYGISDYGLARDIKISRKEAAEFINRYFERYPKVKEYLDNIVKFAR  732
            ++ R +AKAVNFGIVYGISD+GL+ ++ I+RK++  +I+ YFERYP +K Y++N+V+ A+
Sbjct  703  ANDRRNAKAVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAK  762

Query  733  ENGYVLTLFNRKRYIKDINSTNRNTRSYAERIAMNSPIQGSAADIMKLAMIKVYQKLKEN  792
            ++GYV TLF+R+R + DINS N N RS+AER A+NSPIQGSAADI+K+AMI++ + L+  
Sbjct  763  DKGYVETLFKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAG  822

Query  793  NLKAKIILQVHDELLIEAPYEEKDIVKRIVKTEMENAVALKVPLVVEVKEGLNWYETK  850
             ++AK++LQVHDE+++E P +E   +K++VK  ME AV L VPL V+   G +WYE+K
Sbjct  823  GFRAKMLLQVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

494) polA in NC_016894


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  486 bits (1833),  Expect = 3e-138, Method: Compositional matrix adjust.
 Identities = 355/869 (41%), Positives = 582/869 (67%), Gaps = 32/869 (3%)

Query  3    NSKGVPTNAIYGFVNILVKIQEEYQPDYLGVAFDLKGPTFRHLAYEDYKGGRQKMPella  62
            N  G+ TNAIYGF  +L  +    +P  + VAFD    TFR   Y DYK+GR K P+ + 
Sbjct  32   NHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAFDAGKTTFRTEMYADYKAGRAKTPDEFR  91

Query  63   eqflllkellkkMDIAIIELEGFEADDIIGTLATIG--SEKGIQTEIITGDRDAFQLVGP  120
            EQF  ++E+L  ++IA  ELE +EADDIIGTL  ++  +E  ++  I++GD+D +QL + 
Sbjct  92   EQFSYIREMLTALGIAYYELEHYEADDIIGTLDKMAERTEVPFDVTIVSGDKDLIQLTDE  151

Query  121  NIKVLYTKKGISQLEEVDEAWINTQYGLTPKDLIDLKALMGDKSDNIPGIAGIGEKTAIK  180
            N  V  +KKG++++EE   A +  + GLTP+++IDLKALMGDKSDNIPG++ IGEKT++K
Sbjct  152  NTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQFIDLKALMGDKSDNIPGVTKIGEKTGLK  211

Query  181  LLQQYGTLEKIYENiee-qkgkqkekiiagkDDAFLSRMLGTIKRDVPWEGDYKELAFHN  239
            LL+++G+LE IYE+I+  + +K KE++I ++D+AFLS+ L+TI+   P   +  ++ ++ 
Sbjct  212  LLHEFGSLEGIYEHIDGFKTSKMKENLINDRDQAFLSKTLATINTASPITIGLDDIVYNG  271

Query  240  IFNPESIELLKELEFNTLLSKINAAEVVETIEKSVSCHKIKTSIEMDHLFAILEQTKEIV  299
               +   ++  E++F   L K  A+++ +     +S + + T++  D LF+      E +
Sbjct  272  PDVASLSQFYDEMDF-VQLKKGLASQMPQEPVAVISYQEV-TNVSAD-LFSA-----EDI  323

Query  300  IYYR------QEETKIYLALGIEKEFYYLNPEVVDGLKFFERLRNLPTIGTLSIASQDLK  353
            +Y+       + E+ I +A G   ++Y        +L ++    ++  +   +IA+ D+K
Sbjct  324  FYFETLRDNYHREAIIGFAWGHGEQIY-----ASTDLSLLAT-DSFKQVFQKPIATYDFK  377

Query  354  NLIHIFHKNEIQVINEGFDTYIATYLLSPGDQRYDLKTAAYKYLDRNILDDEEMFGKGKK  413
                ++    I+++  ++D+ +A YLLS  ++  +L T A  + D ++ +D+ ++GKG K
Sbjct  378  RSKVLLSHLGIELVAPSYDARLANYLLSTVEDN-ELSTIARIFTDISLEEDDTVYGKGAK  436

Query  414  MVAAESLDEQLLADYFVKNCETIRDLKTVLEKELNKTEMMTLFKTIEMPLLEVMAEMEEL  473
               +   D ++L + + ++   + D K+ +   L   E + L++ IE+PL +V+A ME  
Sbjct  437  RAVP---DKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNIELPLANVLAKMEIE  493

Query  474  GFKIDLSQLEVLSKEFENKLTDLTREIYELAETDEFNINSPKQLGEIIFEQLKLP--VVK  531
            G+K++ + L+ ++ +    +  LT+EIY++A  +EFNINSPKQLG I+FE+++LP  + K
Sbjct  494  GIKVNRATLQDMAEQNKVIIEALTQEIYDMA-GQEFNINSPKQLGSILFEKMQLPLEMTK  552

Query  532  KTKTGYSTNIDVLEQLIHFHPIIEKIIDYRMLSKLDSTYGRGLIAFVEPETHKIYSTFNQ  591
            KTKTGYST +DVLE+L  + PI+ KI+DYR ++KL+STY  GL  ++ ++  KI + + Q
Sbjct  553  KTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYILADG-KIHTRYVQ  611

Query  592  TVAATGRLSSSNPNLQNIPVKTEIGREIRRVFVPSTPDRILVGADYSQIELRVLAHLSGD  651
             ++ TGRLSS +PNLQNIP++ E GR IR+ F PS  D +L+++DYSQIELRVLAH+SGD
Sbjct  612  DLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQIELRVLAHISGD  671

Query  652  ENLIDAFKKEQDIHTRTASEIFGVALDA-VTRIQRGQAKAINFGLIYGKQAFSLGKDLGI  710
            E+LI AF+   DIHT TA  +FG+   A VT  +R +AKA+NFG++YG   F+L+++LGI
Sbjct  672  EHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGISDFGLSNNLGI  731

Query  711  SRNEAQDYINLYFARYPKVQVYMENVKRQAKEEGYVTTIWGRRRYIPEMNSRNGMLVQAG  770
            +R++++ YI+ YF RYP ++ YMENV R+AK+ GYV T+  RRR +P++NSRN  +   +
Sbjct  732  TRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDINSRNFNVRSFA  791

Query  771  ERMALNTPIQGSAADIIKLAMIKVYNRLNDENLKAELILQVHDELIIDTPKNEQTQVERL  830
            ER A+N+PIQGSAADI+K+AMI++ + L+   ++A ++LQVHDE++++ P++E T + +L
Sbjct  792  ERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEVPNDELTAIKKL  851

Query  831  IKEEMEGAASLSVPMTVDVNSGTSWFDLK  859
            +K+ ME+A  L+VP+ VD ++G SW++ K
Sbjct  852  VKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

495) CDBI1_05045 in NC_017179


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  481 bits (1815),  Expect = 7e-137, Method: Compositional matrix adjust.
 Identities = 382/897 (43%), Positives = 590/897 (66%), Gaps = 38/897 (4%)

Query  3    KKLIIIDGNSIINRAFYAL----PEMNNKEGLKTNAIYGFTTMLFKMIDIYKPTHISVAF  58
            +KL++IDG+S+  RAF+AL       +N  GL TNAIYGF  ML  M+   +PTH+ VAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  59   DRKAPTFRHLEYKEYKAGRKGMPDELAEQLQPLKDLLDKFKINRLEIDGYEADDIIGTVS  118
            D    TFR   Y +YKAGR   PDE+ EQ+  ++++L  + I   E++ YEADDIIGT+ 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  119  KKAENNG--YKVYIVTGDKDAIQLASDNTTTLITKKGVGEVEEYNFNSVIEKYEMTPAQF  176
            K AE     + V IV+GDKD IQL+ +NT   I+KKGV+E EE+    ++EK  +TP QF
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  177  IDLKGLMGDKSDNIPGVPGIGEKTGIKLIKEFSSIENLIENTDKLKGS-Vkkkieenkei  235
            IDLK+LMGDKSDNIPGV  IGEKTG+KL+ EF+S+E + E+ D +K S +K ++ ++++ 
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRDQ  244

Query  236  aiQSKRLATIIRDVPIEVDLDSMVFGDYDKDELLDKFRYFGFTsllsrlvdlvdsddTEH  295
            A+ SK LATI    PI ++LD +V+ + D   L + +   +F  L   L        ++ 
Sbjct  245  AFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLA-------SQM  297

Query  296  VEEKIEILKLKDTEKFIDEVNKKGQVI-LKTVRGQGNILEKNIIYIFISVDGEKIYYVDS  354
             +E + ++  ++  +   ++    +++ + T+R++    +++ I  F   +GE+IY   S
Sbjct  298  PQEPVAVISYQEVTNVSADLFSAEDIFYFETLRDN---YHREAIIGFAWGHGEQIY--AS  352

Query  355  NEVSKLDS-----IFSNNEIKKYGYNLKDDYISLKPYNINLENMYFDITIAEYLIDSTSS  409
             ++S L +     +F ++ I  Y++  K   + L    I+L    +D  +A+YL+ +   
Sbjct  353  TDLSLLATDSFKQVF-QKPIATYDF--KRSKVLLSHLGIELVAPSYDARLANYLLSTVED  409

Query  410  TSYDCSAIAMkylskkvkskeellgkgVKSKNYEDLEFEDLAEYMGQIICTVKETIPMME  469
               + S+IA  +    +   + + GKG K    +    + L E +++ +  + ++ + M 
Sbjct  410  N--ELSTIARIFTDISLEEDDTVYGKGAKRAVPDK---DVLLEHLARKVKVLLDSKSQML  464

Query  470  RSLMDMSMDGLFYHVEMPLVEVLGHMEYEGIKVDKSILDELSVEFKEIIATLEKEIYELS  529
              L      +L+ ++E+PL +VL+ ME EGIKV+++ L++++ + K II +L +EIY+++
Sbjct  465  DKLTAHEQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMA  524

Query  530  GEPFNINSPKQLGVILFEKLELPI--IKKTKTGYSTNADVLEKLRDKHPIIDKITEYRQI  587
            G+ FNINSPKQLG ILFEK++LP+   KKTKTGYST  DVLE+L    PI+ KI +YRQI
Sbjct  525  GQEFNINSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQI  584

Query  588  VKLNSTYVEGLLNIINPESNRIHSSFNQTITTTGRISSTEPNLQNIPIKMEMGRKIRKVF  647
             KL+STYV GL + I +++ +IH+ + Q +T TGR+SS +PNLQNIPI++E GR IRK F
Sbjct  585  TKLQSTYVIGLQDYILADG-KIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAF  643

Query  648  IA-DDNCKLVDADYSQVELRVLAHMSQDENMIEAFKHHEDIHTKTASQVFNVPME-DVTS  705
             + +++  L+ +DYSQ+ELRVLAH+S DE++I AF++  DIHT TA +VF +    DVT+
Sbjct  644  TPSHEDAVLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTA  703

Query  706  ELRGAAKAVNFGIIYGKSDFGLADDLNIPVPKAKEYIESYFAKYHKIKEFMDTTVEKASE  765
            + R  AKAVNFGI+YG SDFGL+++L I   ++K YI++YF +Y  IK +M+  V  A +
Sbjct  704  NDRRNAKAVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKD  763

Query  766  DGYAVTILNRRRYIPEIKSSNFMERNRGKRFAMNAPIQGSAADIIKIAMINVHkkleenn  825
             GY  T+++RRR +P+I+S NF  R+ + R A+N+PIQGSAADI+KIAMIN++K L+   
Sbjct  764  KGYVETLFKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGG  823

Query  826  lksklilQVHdeliveaiddeidivkkivkeeMENAVNMDVHLDVDLNVGSSWYETK  882
            +++K++LQVHDE+++E  +DE+  +KK+VK+ ME AV++ V L VD + G SWYE+K
Sbjct  824  FRAKMLLQVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

496) polA in NC_013315


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  481 bits (1815),  Expect = 7e-137, Method: Compositional matrix adjust.
 Identities = 382/897 (43%), Positives = 590/897 (66%), Gaps = 38/897 (4%)

Query  3    KKLIIIDGNSIINRAFYAL----PEMNNKEGLKTNAIYGFTTMLFKMIDIYKPTHISVAF  58
            +KL++IDG+S+  RAF+AL       +N  GL TNAIYGF  ML  M+   +PTH+ VAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  59   DRKAPTFRHLEYKEYKAGRKGMPDELAEQLQPLKDLLDKFKINRLEIDGYEADDIIGTVS  118
            D    TFR   Y +YKAGR   PDE+ EQ+  ++++L  + I   E++ YEADDIIGT+ 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  119  KKAENNG--YKVYIVTGDKDAIQLASDNTTTLITKKGVGEVEEYNFNSVIEKYEMTPAQF  176
            K AE     + V IV+GDKD IQL+ +NT   I+KKGV+E EE+    ++EK  +TP QF
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  177  IDLKGLMGDKSDNIPGVPGIGEKTGIKLIKEFSSIENLIENTDKLKGS-Vkkkieenkei  235
            IDLK+LMGDKSDNIPGV  IGEKTG+KL+ EF+S+E + E+ D +K S +K ++ ++++ 
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRDQ  244

Query  236  aiQSKRLATIIRDVPIEVDLDSMVFGDYDKDELLDKFRYFGFTsllsrlvdlvdsddTEH  295
            A+ SK LATI    PI ++LD +V+ + D   L + +   +F  L   L        ++ 
Sbjct  245  AFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLA-------SQM  297

Query  296  VEEKIEILKLKDTEKFIDEVNKKGQVI-LKTVRGQGNILEKNIIYIFISVDGEKIYYVDS  354
             +E + ++  ++  +   ++    +++ + T+R++    +++ I  F   +GE+IY   S
Sbjct  298  PQEPVAVISYQEVTNVSADLFSAEDIFYFETLRDN---YHREAIIGFAWGHGEQIY--AS  352

Query  355  NEVSKLDS-----IFSNNEIKKYGYNLKDDYISLKPYNINLENMYFDITIAEYLIDSTSS  409
             ++S L +     +F ++ I  Y++  K   + L    I+L    +D  +A+YL+ +   
Sbjct  353  TDLSLLATDSFKQVF-QKPIATYDF--KRSKVLLSHLGIELVAPSYDARLANYLLSTVED  409

Query  410  TSYDCSAIAMkylskkvkskeellgkgVKSKNYEDLEFEDLAEYMGQIICTVKETIPMME  469
               + S+IA  +    +   + + GKG K    +    + L E +++ +  + ++ + M 
Sbjct  410  N--ELSTIARIFTDISLEEDDTVYGKGAKRAVPDK---DVLLEHLARKVKVLLDSKSQML  464

Query  470  RSLMDMSMDGLFYHVEMPLVEVLGHMEYEGIKVDKSILDELSVEFKEIIATLEKEIYELS  529
              L      +L+ ++E+PL +VL+ ME EGIKV+++ L++++ + K II +L +EIY+++
Sbjct  465  DKLTAHEQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMA  524

Query  530  GEPFNINSPKQLGVILFEKLELPI--IKKTKTGYSTNADVLEKLRDKHPIIDKITEYRQI  587
            G+ FNINSPKQLG ILFEK++LP+   KKTKTGYST  DVLE+L    PI+ KI +YRQI
Sbjct  525  GQEFNINSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQI  584

Query  588  VKLNSTYVEGLLNIINPESNRIHSSFNQTITTTGRISSTEPNLQNIPIKMEMGRKIRKVF  647
             KL+STYV GL + I +++ +IH+ + Q +T TGR+SS +PNLQNIPI++E GR IRK F
Sbjct  585  TKLQSTYVIGLQDYILADG-KIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAF  643

Query  648  IA-DDNCKLVDADYSQVELRVLAHMSQDENMIEAFKHHEDIHTKTASQVFNVPME-DVTS  705
             + +++  L+ +DYSQ+ELRVLAH+S DE++I AF++  DIHT TA +VF +    DVT+
Sbjct  644  TPSHEDAVLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTA  703

Query  706  ELRGAAKAVNFGIIYGKSDFGLADDLNIPVPKAKEYIESYFAKYHKIKEFMDTTVEKASE  765
            + R  AKAVNFGI+YG SDFGL+++L I   ++K YI++YF +Y  IK +M+  V  A +
Sbjct  704  NDRRNAKAVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKD  763

Query  766  DGYAVTILNRRRYIPEIKSSNFMERNRGKRFAMNAPIQGSAADIIKIAMINVHkkleenn  825
             GY  T+++RRR +P+I+S NF  R+ + R A+N+PIQGSAADI+KIAMIN++K L+   
Sbjct  764  KGYVETLFKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGG  823

Query  826  lksklilQVHdeliveaiddeidivkkivkeeMENAVNMDVHLDVDLNVGSSWYETK  882
            +++K++LQVHDE+++E  +DE+  +KK+VK+ ME AV++ V L VD + G SWYE+K
Sbjct  824  FRAKMLLQVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

497) polA in NC_013316


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  481 bits (1815),  Expect = 7e-137, Method: Compositional matrix adjust.
 Identities = 382/897 (43%), Positives = 590/897 (66%), Gaps = 38/897 (4%)

Query  3    KKLIIIDGNSIINRAFYAL----PEMNNKEGLKTNAIYGFTTMLFKMIDIYKPTHISVAF  58
            +KL++IDG+S+  RAF+AL       +N  GL TNAIYGF  ML  M+   +PTH+ VAF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  59   DRKAPTFRHLEYKEYKAGRKGMPDELAEQLQPLKDLLDKFKINRLEIDGYEADDIIGTVS  118
            D    TFR   Y +YKAGR   PDE+ EQ+  ++++L  + I   E++ YEADDIIGT+ 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  119  KKAENNG--YKVYIVTGDKDAIQLASDNTTTLITKKGVGEVEEYNFNSVIEKYEMTPAQF  176
            K AE     + V IV+GDKD IQL+ +NT   I+KKGV+E EE+    ++EK  +TP QF
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  177  IDLKGLMGDKSDNIPGVPGIGEKTGIKLIKEFSSIENLIENTDKLKGS-Vkkkieenkei  235
            IDLK+LMGDKSDNIPGV  IGEKTG+KL+ EF+S+E + E+ D +K S +K ++ ++++ 
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRDQ  244

Query  236  aiQSKRLATIIRDVPIEVDLDSMVFGDYDKDELLDKFRYFGFTsllsrlvdlvdsddTEH  295
            A+ SK LATI    PI ++LD +V+ + D   L + +   +F  L   L        ++ 
Sbjct  245  AFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLA-------SQM  297

Query  296  VEEKIEILKLKDTEKFIDEVNKKGQVI-LKTVRGQGNILEKNIIYIFISVDGEKIYYVDS  354
             +E + ++  ++  +   ++    +++ + T+R++    +++ I  F   +GE+IY   S
Sbjct  298  PQEPVAVISYQEVTNVSADLFSAEDIFYFETLRDN---YHREAIIGFAWGHGEQIY--AS  352

Query  355  NEVSKLDS-----IFSNNEIKKYGYNLKDDYISLKPYNINLENMYFDITIAEYLIDSTSS  409
             ++S L +     +F ++ I  Y++  K   + L    I+L    +D  +A+YL+ +   
Sbjct  353  TDLSLLATDSFKQVF-QKPIATYDF--KRSKVLLSHLGIELVAPSYDARLANYLLSTVED  409

Query  410  TSYDCSAIAMkylskkvkskeellgkgVKSKNYEDLEFEDLAEYMGQIICTVKETIPMME  469
               + S+IA  +    +   + + GKG K    +    + L E +++ +  + ++ + M 
Sbjct  410  N--ELSTIARIFTDISLEEDDTVYGKGAKRAVPDK---DVLLEHLARKVKVLLDSKSQML  464

Query  470  RSLMDMSMDGLFYHVEMPLVEVLGHMEYEGIKVDKSILDELSVEFKEIIATLEKEIYELS  529
              L      +L+ ++E+PL +VL+ ME EGIKV+++ L++++ + K II +L +EIY+++
Sbjct  465  DKLTAHEQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMA  524

Query  530  GEPFNINSPKQLGVILFEKLELPI--IKKTKTGYSTNADVLEKLRDKHPIIDKITEYRQI  587
            G+ FNINSPKQLG ILFEK++LP+   KKTKTGYST  DVLE+L    PI+ KI +YRQI
Sbjct  525  GQEFNINSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQI  584

Query  588  VKLNSTYVEGLLNIINPESNRIHSSFNQTITTTGRISSTEPNLQNIPIKMEMGRKIRKVF  647
             KL+STYV GL + I +++ +IH+ + Q +T TGR+SS +PNLQNIPI++E GR IRK F
Sbjct  585  TKLQSTYVIGLQDYILADG-KIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAF  643

Query  648  IA-DDNCKLVDADYSQVELRVLAHMSQDENMIEAFKHHEDIHTKTASQVFNVPME-DVTS  705
             + +++  L+ +DYSQ+ELRVLAH+S DE++I AF++  DIHT TA +VF +    DVT+
Sbjct  644  TPSHEDAVLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTA  703

Query  706  ELRGAAKAVNFGIIYGKSDFGLADDLNIPVPKAKEYIESYFAKYHKIKEFMDTTVEKASE  765
            + R  AKAVNFGI+YG SDFGL+++L I   ++K YI++YF +Y  IK +M+  V  A +
Sbjct  704  NDRRNAKAVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKD  763

Query  766  DGYAVTILNRRRYIPEIKSSNFMERNRGKRFAMNAPIQGSAADIIKIAMINVHkkleenn  825
             GY  T+++RRR +P+I+S NF  R+ + R A+N+PIQGSAADI+KIAMIN++K L+   
Sbjct  764  KGYVETLFKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGG  823

Query  826  lksklilQVHdeliveaiddeidivkkivkeeMENAVNMDVHLDVDLNVGSSWYETK  882
            +++K++LQVHDE+++E  +DE+  +KK+VK+ ME AV++ V L VD + G SWYE+K
Sbjct  824  FRAKMLLQVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

498) Adeg_1024 in NC_013385


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  474 bits (1788),  Expect = 9e-135, Method: Compositional matrix adjust.
 Identities = 359/892 (41%), Positives = 557/892 (63%), Gaps = 56/892 (6%)

Query  4    KTLLLLDGSSIAYRAFFAL----PSLRTRTGLPTGAVYGFTSMLFKVLEERRPTAIVAAF  59
            + LLL+DGSS+A+RAFFAL      ++ ++GL T A+YGF  ML  ++   RPT ++ AF
Sbjct  5    NKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAF  64

Query  60   DKSKTTFRHALAETYKAHRPATPDELRQQFNLIKEVLTALNVPVVEKEGFEADDLIGTLV  119
            D +KTTFR  +   YKA R+ TPDE+R+QF+ I+E+LTAL ++  E E +EADD+IGTL 
Sbjct  65   DAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLD  124

Query  120  DRAEKEG--WQCLIVTGDLDALQLVSPLTTVVLMRKGISEIAVFNEAEVKRRFGVTPRQL  177
              AE+     +  IV+GD D +QL    T V + +KG++E+  F  A +  + G+TP Q+
Sbjct  125  KMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEEFTPAYLMEKMGLTPNQF  184

Query  178  PDFKALAGDASDNIPGLPGIGPKTASRllqshqslekl-leskeslPAKLRETLERHKEE  236
             D+KAL GD SDNIPG+  IG KT+ +LL+   SLE +  +      +K++E L  ++++
Sbjct  185  IDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRDQ  244

Query  237  AVLAKKLALIRRDVPLE---EEIIRPWPGPNILATLEVFSRLEFRTLAKRFLELFPEARL  293
            A L+K LA I    P+    ++I+    GP++ +  + +  ++F  L K +    P+  +
Sbjct  245  AFLSKTLATINTASPITIGLDDIV--YNGPDVASLSQFYDEMDFVQLKKGLASQMPQEPV  302

Query  294  LSASGLTPSAVRVKVerpeelerlgeelgrqeFAALAYPPVLRRK-ATSSFLALCLG-GE  351
               S    + V   +  +                 + Y   LR +    +++++  G GE
Sbjct  303  AVISYQEVTNVSADLFSA---------------EDIFYFETLRDNYHREAIIGFAWGHGE  347

Query  352  KVFLLEGPEVLKS-FFRLLEEKGGLVSTYDAKSCLHALEPYGFKPEMIGFDVLLAAYLVN  410
            +++   +  +L +  F+ + +K   ++TYD K     L   G+     ++D  LA YL++
Sbjct  348  QIYASTDLSLLATDSFKQVFQKP--IATYDFKRSKVLLSHLGIELVAPSYDARLANYLLS  405

Query  411  PAANNELGAIA--F-------EHAGFMLSPGAELPEKAQAIYQLTPILK----------S  451
               +NEL++IA  F       +++ +  ++   +P+K   + +L+  +K           
Sbjct  406  TVEDNELSTIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLD  465

Query  452  KIKLQEQEYLYYSVELPLAAVLADMEKVGVKVSEERLRSLSKELGEQLAQLSEEIYKLAG  511
            K+  +EQ  LY ++ELPLA VLA ME  G+KV+   L+ ++ +    +  L++EIY +AG
Sbjct  466  KLTAHEQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAG  525

Query  512  ERFNLNSPRQLGYILFEK--LGLKPVKKTKTGYSTDASVLEKLAE-HEIVAKVLVYRQLA  568
            + FN+NSP+QLG ILFEK  L L   KKTKTGYST   VLE+LA    IVAK+L YRQ++
Sbjct  526  QEFNINSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQIT  585

Query  569  KLKSTYTDALPELIDPATGRLHTTFLQAGTATGRLASAEPNLQNIPVRDSLGRRIRQAFV  628
            KL+STY  +L + I  A G++HT ++Q  T TGRL+S +PNLQNIP+R   GR IR+AF 
Sbjct  586  KLQSTYVIGLQDYI-LADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFT  644

Query  629  AEGPDYVLLSADYSQIELRVLAHLSEDPGLCEAFVKGEDIHARTAAEIFGVS-PQEVTPE  687
            +   D VLLS+DYSQIELRVLAH+S D  L  AF  G DIH+ TA  +FG+  + +VT++
Sbjct  645  PSHEDAVLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTAN  704

Query  688  MRAKAKVVNFGIVYGMSDYGLSQELKIEPGEAHEYIERYFRRYPRVKQFIERVIAQAREK  747
             R +AK VNFGIVYG+SD+GLS++L I   ++  YI+ YF RYP +K ++E V+ +A++K
Sbjct  705  DRRNAKAVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDK  764

Query  748  GYVTTILNRRRYIPEILSSNRNQRQLGERLAINTTIQGSAADLIKKAMVDIHRQLKGQGF  807
            GYV T+++RRR +P+I S N N R ++ER AIN+ IQGSAAD++K AM+++++ L++ GF
Sbjct  765  GYVETLFKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGF  824

Query  808  KCRMILQVHDELLFEVPKEELEKVAPIIKSTMEQALPFKVPIKANLKVGPNW  859
            + +M+LQVHDE+++EVP++EL  +  ++K TME A+ + VP+  +   G +W
Sbjct  825  RAKMLLQVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSW  876

499) COB47_1113 in NC_014392


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  467 bits (1759),  Expect = 2e-132, Method: Compositional matrix adjust.
 Identities = 373/898 (42%), Positives = 566/898 (64%), Gaps = 72/898 (8%)

Query  2    KLVIFDGNSILYRAFFAL----PELTTSSNIPTNAIYGFINVILKYLEQENPDYVAVAFD  57
            KL+++DG+S+ +RAFFAL      +   S + TNAIYGF  ++   + +  P  V VAFD
Sbjct  6    KLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVRPTHVLVAFD  65

Query  58   KKGRQARKSEYEEYKANRKPMPDNLQVQIPYVREILYALNIPIIEFEGYEADDVIGSLVN  117
                  R   Y +YKA R   PD+++ Q++Y+RE+L AL I+  E+E YEADD+IG+L +
Sbjct  66   AGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLTALGIAYYELEHYEADDIIGTLDK  125

Query  118  MFKNTDL--DIVIITGDKDTLQLLDKNVVVKIVSTKFDKTTEDLYTAENVKEKYGVWANQ  175
            M   T++  D+ I++GDKD +QL D N VV I         E  +T+  + EK G+ +NQ
Sbjct  126  MAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKKGVAEFEE--FTPAYLMEKMGLTPNQ  183

Query  176  VPDYKALVGDQSDNIPGVKGIGAKSAQKlleeyssleeIYQNLNNIKGS-IREKLEASKD  234
              D KAL+GD+SDNIPGV  IG K++ KLL+E++SLE IY++++ +K S ++E+L   +D
Sbjct  184  FIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLINDRD  243

Query  235  IAFLSKRLATIVCDLPLNIKLEDLRTREWNKKRLYEILLQLEFKSIIKRLGLSEEVQVEF  294
             AFLSK LATI    P+ I L+D+     +   L ++  +++F  + K  GL+ ++  E 
Sbjct  244  QAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKK--GLASQMPQEP  301

Query  295  VQQLTNIHDVEQKKLEGISQIRSKDISLMFVPEEKCFYL------YDQESNTVFV---TE  345
            V  ++          + ++++ +     +F +E+  FY+      Y++E+   F     E
Sbjct  302  VAVIS---------YQEVTNVSAD----LFSAED-IFYFETLRDNYHREAIIGFAWGHGE  347

Query  346  ERHLVEEI--LKSESVKIV-------YDLKN---IFHELYLENTDNIRNCEDVMIASYVL  393
            +     ++  L ++S K V       YD+K    ++ +L     + +    D  +A+Y+L
Sbjct  348  QIYASTDLSLLATDSFKQVFQKPIATYDFKRSKVLLSHL---GIELVAPSYDARLANYLL  404

Query  394  DSTRSSYELETLFISYLNTDLAA-----VKKDKKVTSV--ILLKRLWDELSSLIDLNSCQ  446
             +   + EL T+   + +  L        K  K+  +   +LL +L   +  L+D +S  
Sbjct  405  STVEDN-ELSTIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQM  463

Query  447  F----------VYTNIERPLIPILYEMEKAGFKVDRDALLQYTKEIESKILNLEKQIYQI  496
            +          +Y NIE PL  +L  ME  G+KV+R +L + + +    I  L ++IY++
Sbjct  464  LDKLTAHEQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDM  523

Query  497  AGEWFNINSPKQLSYILFEKLKLP--VIKKTKTGYSTDAEVLEELFDKHEIVPLILDYRM  554
            AG+ FNINSPKQL+ ILFEK++LP  + KKTKTGYST  +VLE L     IV+ ILDYR 
Sbjct  524  AGQEFNINSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQ  583

Query  555  YTKILTTYCQGLLQAINPSSGRVHTTFIQTGTATGRLASSDPNLQNIPVKYDEGRLIRKV  614
             TK+ +TY  GL Q    + G++HT ++Q  T TGRL+S DPNLQNIP++ ++GRLIRK 
Sbjct  584  ITKLQSTYVIGL-QDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKA  642

Query  615  FIP-EEGHVLIDADYSQIELRILAHISEDERLINAFKNNVDIHSQTAAEVFGVD-IDDVT  672
            F P +E+ VL+ +DYSQIELR+LAHIS DE+LI AF++  DIH+ TA  VFG+D   DVT
Sbjct  643  FTPSHEDAVLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVT  702

Query  673  PEMRSQAKAVNFGIVYGISDYGLARDIKISRKEAAEFINRYFERYPKVKEYLDNIVKFAR  732
            ++ R +AKAVNFGIVYGISD+GL+ ++ I+RK++  +I+ YFERYP +K Y++N+V+ A+
Sbjct  703  ANDRRNAKAVNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAK  762

Query  733  DNGYVLTLFNRRRYVKDIKSANRNARNYAERIAMNSPIQGSAADIMKLAMIKVYQKLKEN  792
            D+GYV TLF+RRR + DI+S N N R++AER A+NSPIQGSAADI+K+AMI++ + L+  
Sbjct  763  DKGYVETLFKRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAG  822

Query  793  NLKSKIILQVHDELLIEAPYEEKDIVKEIVKREMENAVALKVPLVVEVKEGLNWYETK  850
             +++K++LQVHDE+++E P +E   +K +VK  ME AV L VPL V+   G +WYE+K
Sbjct  823  GFRAKMLLQVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880

500) EC1_00380 in NC_021019


> NC_007297_P1|24|G24|71909973|YP_281523.1|Streptococcus_pyogenes_MGAS5005|+|25717..28359|polA|M5005_Spy_0159|DNA 
polymerase 
I
Length=880

 Score =  444 bits (1674),  Expect = 8e-126, Method: Compositional matrix adjust.
 Identities = 298/709 (43%), Positives = 477/709 (68%), Gaps = 32/709 (4%)

Query  2    PKQIIDLKGIMGDSSDNIPGVAGIGEKGATKLLVQYGSLENVYENIDQIK-GKQKEKLLN  60
            P+Q+IDLK++MGD SDNIPGV+ IGEK + KLL ++GSLE +YE+ID +K +K KE+L+N
Sbjct  181  PNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN  240

Query  61   DKENAFMSKELATIYTSMDFPFTIQDCKFDGYD-EKVNDFYQ-------KYEMRSLISKT  112
            D+++AF+SK LATI T+  + + ++D  ++G D   +++FY+       K  + S +++ 
Sbjct  241  DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQE  300

Query  113  TMTSKSYQIKTICSFKGYDSKDLLLMPVNSKEAYLNQKLYGFMFFNNEEVLYLKVE-DAL  171
             ++  SYQ  T  S   + + D++      ++ Y  + + GF   + E++ Y   +   L
Sbjct  301  PVAVISYQEVTNVSADLFSAEDIFYFE-TLRDNYHREAIIGFAWGHGEQI-YASTDLSLL  358

Query  172  EDSYFKNMLKHETSLRTWDAKEMMHLLQRYG--FYVPSFKEDLHLAAFLL----HSQATD  225
                FK+++  + ++ T D K    LL + G  +  PS+  D +LA +LL    +++ + 
Sbjct  359  ATDSFKQVF--QKPIATYDFKRSKVLLSHLGIELVAPSY--DARLANYLLSTVEDNELST  414

Query  226  TDSLISSLGIELPETIHDLLKKAKTVEACHIDRLLPVTCAWTWQLSIRQDNIFDELKKDN  285
               +++ +++E  +T+ +   K+      + D LL         L   + +++D L  ++
Sbjct  415  IARIFTDISLEEDDTVYG---KGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHE  471

Query  286  LLDLYENIEKPLVRILFEMENQGIHIDENVLDEIGAKTDTILESLTQQIHEMAHMVFNIN  345
             LDLY+NIE PL  +L  ME +GI ++   L++++ +   I+E+LTQ+I +MA   FNIN
Sbjct  472  QLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNIN  531

Query  346  SPKQLAGVLYDELNLKGGGKKR-----STSAEVLEKLKGSHPIIDVLLDYRKYSKIKSTY  400
            SPKQL+++L++ ++L     K+     ST+ +VLE+L    PI+  +LDYR+ +K++STY
Sbjct  532  SPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLERLAPIAPIVAKILDYRQITKLQSTY  591

Query  401  IEGLKKHIQQDSKIHTCFNQAMTQTGRLSSSDPNLQNISVRDEQGREIRKAFVA-QKGYK  459
            + GL+  I  D+KIHT + Q +TQTGRLSS DPNLQNI++R EQGR IRKAF + + +  
Sbjct  592  VIGLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIRKAFTPSHEDAV  651

Query  460  LLSADYSQIELRMLAHMANETHMIEAFKEGADIHNRTASHIFHVSQE-DVTPDMRRVAKT  518
            LLS+DYSQIELR+LAH++ + H+I AF+EGADIH  TA ++F + +  DVT++ RR AK+
Sbjct  652  LLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKA  711

Query  519  VNFGIVYGQTEFGLSQQLKISRKEAGEFMETYFASYPNIHQFMNQLIDFCKENGYVETMF  578
            VNFGIVYG ++FGLS++L I+RK++  +++TYF  YP I  +M++++   K++GYVET+F
Sbjct  712  VNFGIVYGISDFGLSNNLGITRKQSKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLF  771

Query  579  HRRRMIPEINDKNFMTREFGKRAAMNAPIQGSAADLIKIAMIRVDQAMKEKNVKSKMLLQ  638
             RRR +P+IN +NF  R F+ R+A+N+PIQGSAAD++KIAMI +D+A++    ++KMLLQ
Sbjct  772  KRRRELPDINSRNFNVRSFAERTAINSPIQGSAADILKIAMINLDKALQAGGFRAKMLLQ  831

Query  639  IHDELIFLVPDDELEVMQALVKEAMEQAMELKVPLKASINFGQSWYEAK  687
            +HDE+++ VP+DEL  ++ LVK++ME A++L VPL    + GQSWYEAK
Sbjct  832  VHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK  880