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PAthogenisity Island DataBase (PAI DB)

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Homologs of intI1 gene of JF262175

protein-level

Hit (GenBank Accn)

Product

Source Genome

Eval.

Ident.(%)

1) ABTJ_02575
( YP_006290465.1 )

integron integrase

NC_017847
(Acinetobacter baumannii MDR-TJ)

2e-95

2) ABK1_1144
( YP_005513716.1 )

intI

NC_017162
(Acinetobacter baumannii 1656-2)

4e-95

3) BJAB07104_p0087
( YP_008211310.1 )

Integrase

NC_021728
(Acinetobacter baumannii BJAB07104)

2e-94

4) ABTJ_01324
( YP_006289230.1 )

integron integrase

NC_017847
(Acinetobacter baumannii MDR-TJ)

2e-94

5) M3Q_2665
( YP_006848984.1 )

class I integrase

NC_018706
(Acinetobacter baumannii TYTH-1)

2e-94

6) BJAB0868_p0098
( YP_008215130.1 )

Integrase

NC_021732
(Acinetobacter baumannii BJAB0868)

3e-94

7) DIP1947
( NP_940279.1 )

integrase

NC_002935
(Corynebacterium diphtheriae NCTC13129)

1e-79

8) azo3724
( YP_935226.1 )

truncated integrase/recombinase

NC_008702
(Azoarcus sp. BH72)

9e-56

9) Pmen_3075
( YP_001188561.1 )

integron integrase

NC_009439
(Pseudomonas mendocina ymp)

3e-50

10) DSC_01675
( YP_004929029.1 )

putative integrase

NC_016147
(Pseudoxanthomonas spadix BD-a59)

2e-47

11) Rcas_2866
( YP_001432950.1 )

integron integrase

NC_009767
(Roseiflexus castenholzii DSM 13941)

1e-41

12) Nwat_1933
( YP_003761095.1 )

integron integrase

NC_014315
(Nitrosococcus watsonii C-113)

7e-40

• Sequence Alignments

1) ABTJ_02575 in NC_017847


> JF262175|4|G2|325301789|ADZ05801.1|Acinetobacter_baumannii_NIPH2554|-|1437..2118|intI1|-|integrase
Length=227

 Score =  341 bits (1280),  Expect = 2e-95, Method: Compositional matrix adjust.
 Identities = 226/227 (99%), Positives = 227/227 (100%), Gaps = 0/227 (0%)

Query  1    MKTATAPLPPLRSVKVLDQLRERIRYLHYSLRTEQAYVNWVRAFIRFHGVRHPATLGSSE  60
            MKTATAPLPPLRSVKVLDQLRERIRYLHYSLRTEQAYVNWVRAFIRFHGVRHPATLGSSE
Sbjct  1    MKTATAPLPPLRSVKVLDQLRERIRYLHYSLRTEQAYVNWVRAFIRFHGVRHPATLGSSE  60

Query  61   VEAFLSWLANERKVSVSTHRQALAALLFFYGKVLCTDLPWLQEIGrprpsrrlpvvltpD  120
            VEAFLSWLANERKVSVSTHRQALAALLFFYGKVLCTDLPWLQEIGRPRPSRRLPVVLTPD
Sbjct  61   VEAFLSWLANERKVSVSTHRQALAALLFFYGKVLCTDLPWLQEIGRPRPSRRLPVVLTPD  120

Query  121  EVVRILGFLEGEHRLFAQLLYGTGMRISEGLQLRVKDLDFDHGTIIVREGKGSKDRALML  180
            EVVRILGFLE+EHRLFAQLLYGTGMRISEGLQLRVKDLDFDHGTIIVREGKGSKDRALML
Sbjct  121  EVVRILGFLESEHRLFAQLLYGTGMRISEGLQLRVKDLDFDHGTIIVREGKGSKDRALML  180

Query  181  PESLAPSLREQLSRARAWWLKDQAEGRSGVALPDALERKYPRAGHSW  227
            PESLAPSLREQLSRARAWWLKDQAEGRSGVALPDALERKYPRAGHSW
Sbjct  181  PESLAPSLREQLSRARAWWLKDQAEGRSGVALPDALERKYPRAGHSW  227

2) ABK1_1144 in NC_017162


> JF262175|4|G2|325301789|ADZ05801.1|Acinetobacter_baumannii_NIPH2554|-|1437..2118|intI1|-|integrase
Length=227

 Score =  340 bits (1278),  Expect = 4e-95, Method: Compositional matrix adjust.
 Identities = 226/227 (99%), Positives = 227/227 (100%), Gaps = 0/227 (0%)

Query  1    MKTATAPLPPLRSVKVLDQLRERIRYLHYSLRTEQAYVNWVRAFIRFHGVRHPATLGSSE  60
            MKTATAPLPPLRSVKVLDQLRERIRYLHYSLRTEQAYVNWVRAFIRFHGVRHPATLGSSE
Sbjct  1    MKTATAPLPPLRSVKVLDQLRERIRYLHYSLRTEQAYVNWVRAFIRFHGVRHPATLGSSE  60

Query  61   VEAFLSWLANERKVSVSTHRQALAALLFFYGKVLCTDLPWLQEIGrprpsrrlpvvltpD  120
            VEAFLSWLANERKVSVSTHRQALAALLFFYGKVLCTDLPWLQEIGRPRPSRRLPVVLTPD
Sbjct  61   VEAFLSWLANERKVSVSTHRQALAALLFFYGKVLCTDLPWLQEIGRPRPSRRLPVVLTPD  120

Query  121  EVVRILGFLEGEHRLFAQLLYGTGMRISEGLQLRVKDLDFDHGTIIVREGKGSKDRALML  180
            EVVRILGFLE+EHRLFAQLLYGTGMRISEGLQLRVKDLDFDHGTIIVREGKGSKDRALML
Sbjct  121  EVVRILGFLESEHRLFAQLLYGTGMRISEGLQLRVKDLDFDHGTIIVREGKGSKDRALML  180

Query  181  PESLAPSLREQLSRARAWWLKDQAEGRSGVALPDALERKYPRAGHSW  227
            PESLAPSLREQLSRARAWWLKDQAEGRSGVALPDALERKYPRAGHSW
Sbjct  181  PESLAPSLREQLSRARAWWLKDQAEGRSGVALPDALERKYPRAGHSW  227

3) BJAB07104_p0087 in NC_021728


> JF262175|4|G2|325301789|ADZ05801.1|Acinetobacter_baumannii_NIPH2554|-|1437..2118|intI1|-|integrase
Length=227

 Score =  338 bits (1270),  Expect = 2e-94, Method: Compositional matrix adjust.
 Identities = 225/227 (99%), Positives = 226/227 (99%), Gaps = 0/227 (0%)

Query  1    MKTATAPLPPLRSVKVLDQLRERIRYLHYSLPTEQAYVNWVRAFIRFHGVRHPATLGSSE  60
            MKTATAPLPPLRSVKVLDQLRERIRYLHYSL TEQAYVNWVRAFIRFHGVRHPATLGSSE
Sbjct  1    MKTATAPLPPLRSVKVLDQLRERIRYLHYSLRTEQAYVNWVRAFIRFHGVRHPATLGSSE  60

Query  61   VEAFLSWLANERKVSVSTHRQALAALLFFYGKVLCTDLPWLQEIGrprpsrrlpvvltpD  120
            VEAFLSWLANERKVSVSTHRQALAALLFFYGKVLCTDLPWLQEIGRPRPSRRLPVVLTPD
Sbjct  61   VEAFLSWLANERKVSVSTHRQALAALLFFYGKVLCTDLPWLQEIGRPRPSRRLPVVLTPD  120

Query  121  EVVRILGFLEGEHRLFAQLLYGTGMRISEGLQLRVKDLDFDHGTIIVREGKGSKDRALML  180
            EVVRILGFLE+EHRLFAQLLYGTGMRISEGLQLRVKDLDFDHGTIIVREGKGSKDRALML
Sbjct  121  EVVRILGFLESEHRLFAQLLYGTGMRISEGLQLRVKDLDFDHGTIIVREGKGSKDRALML  180

Query  181  PESLAPSLREQLSRARAWWLKDQAEGRSGVALPDALERKYPRAGHSW  227
            PESLAPSLREQLSRARAWWLKDQAEGRSGVALPDALERKYPRAGHSW
Sbjct  181  PESLAPSLREQLSRARAWWLKDQAEGRSGVALPDALERKYPRAGHSW  227

4) ABTJ_01324 in NC_017847


> JF262175|4|G2|325301789|ADZ05801.1|Acinetobacter_baumannii_NIPH2554|-|1437..2118|intI1|-|integrase
Length=227

 Score =  338 bits (1270),  Expect = 2e-94, Method: Compositional matrix adjust.
 Identities = 225/227 (99%), Positives = 226/227 (99%), Gaps = 0/227 (0%)

Query  1    MKTATAPLPPLRSVKVLDQLRERIRYLHYSLPTEQAYVNWVRAFIRFHGVRHPATLGSSE  60
            MKTATAPLPPLRSVKVLDQLRERIRYLHYSL TEQAYVNWVRAFIRFHGVRHPATLGSSE
Sbjct  1    MKTATAPLPPLRSVKVLDQLRERIRYLHYSLRTEQAYVNWVRAFIRFHGVRHPATLGSSE  60

Query  61   VEAFLSWLANERKVSVSTHRQALAALLFFYGKVLCTDLPWLQEIGrprpsrrlpvvltpD  120
            VEAFLSWLANERKVSVSTHRQALAALLFFYGKVLCTDLPWLQEIGRPRPSRRLPVVLTPD
Sbjct  61   VEAFLSWLANERKVSVSTHRQALAALLFFYGKVLCTDLPWLQEIGRPRPSRRLPVVLTPD  120

Query  121  EVVRILGFLEGEHRLFAQLLYGTGMRISEGLQLRVKDLDFDHGTIIVREGKGSKDRALML  180
            EVVRILGFLE+EHRLFAQLLYGTGMRISEGLQLRVKDLDFDHGTIIVREGKGSKDRALML
Sbjct  121  EVVRILGFLESEHRLFAQLLYGTGMRISEGLQLRVKDLDFDHGTIIVREGKGSKDRALML  180

Query  181  PESLAPSLREQLSRARAWWLKDQAEGRSGVALPDALERKYPRAGHSW  227
            PESLAPSLREQLSRARAWWLKDQAEGRSGVALPDALERKYPRAGHSW
Sbjct  181  PESLAPSLREQLSRARAWWLKDQAEGRSGVALPDALERKYPRAGHSW  227

5) M3Q_2665 in NC_018706


> JF262175|4|G2|325301789|ADZ05801.1|Acinetobacter_baumannii_NIPH2554|-|1437..2118|intI1|-|integrase
Length=227

 Score =  338 bits (1270),  Expect = 2e-94, Method: Compositional matrix adjust.
 Identities = 225/227 (99%), Positives = 226/227 (99%), Gaps = 0/227 (0%)

Query  1    MKTATAPLPPLRSVKVLDQLRERIRYLHYSLPTEQAYVNWVRAFIRFHGVRHPATLGSSE  60
            MKTATAPLPPLRSVKVLDQLRERIRYLHYSL TEQAYVNWVRAFIRFHGVRHPATLGSSE
Sbjct  1    MKTATAPLPPLRSVKVLDQLRERIRYLHYSLRTEQAYVNWVRAFIRFHGVRHPATLGSSE  60

Query  61   VEAFLSWLANERKVSVSTHRQALAALLFFYGKVLCTDLPWLQEIGrprpsrrlpvvltpD  120
            VEAFLSWLANERKVSVSTHRQALAALLFFYGKVLCTDLPWLQEIGRPRPSRRLPVVLTPD
Sbjct  61   VEAFLSWLANERKVSVSTHRQALAALLFFYGKVLCTDLPWLQEIGRPRPSRRLPVVLTPD  120

Query  121  EVVRILGFLEGEHRLFAQLLYGTGMRISEGLQLRVKDLDFDHGTIIVREGKGSKDRALML  180
            EVVRILGFLE+EHRLFAQLLYGTGMRISEGLQLRVKDLDFDHGTIIVREGKGSKDRALML
Sbjct  121  EVVRILGFLESEHRLFAQLLYGTGMRISEGLQLRVKDLDFDHGTIIVREGKGSKDRALML  180

Query  181  PESLAPSLREQLSRARAWWLKDQAEGRSGVALPDALERKYPRAGHSW  227
            PESLAPSLREQLSRARAWWLKDQAEGRSGVALPDALERKYPRAGHSW
Sbjct  181  PESLAPSLREQLSRARAWWLKDQAEGRSGVALPDALERKYPRAGHSW  227

6) BJAB0868_p0098 in NC_021732


> JF262175|4|G2|325301789|ADZ05801.1|Acinetobacter_baumannii_NIPH2554|-|1437..2118|intI1|-|integrase
Length=227

 Score =  337 bits (1266),  Expect = 3e-94, Method: Compositional matrix adjust.
 Identities = 224/227 (99%), Positives = 225/227 (99%), Gaps = 0/227 (0%)

Query  1    MKPATAPLPPLRSVKVLDQLRERIRYLHYSLPTEQAYVNWVRAFIRFHGVRHPATLGSSE  60
            MK ATAPLPPLRSVKVLDQLRERIRYLHYSL TEQAYVNWVRAFIRFHGVRHPATLGSSE
Sbjct  1    MKTATAPLPPLRSVKVLDQLRERIRYLHYSLRTEQAYVNWVRAFIRFHGVRHPATLGSSE  60

Query  61   VEAFLSWLANERKVSVSTHRQALAALLFFYGKVLCTDLPWLQEIGrprpsrrlpvvltpD  120
            VEAFLSWLANERKVSVSTHRQALAALLFFYGKVLCTDLPWLQEIGRPRPSRRLPVVLTPD
Sbjct  61   VEAFLSWLANERKVSVSTHRQALAALLFFYGKVLCTDLPWLQEIGRPRPSRRLPVVLTPD  120

Query  121  EVVRILGFLEGEHRLFAQLLYGTGMRISEGLQLRVKDLDFDHGTIIVREGKGSKDRALML  180
            EVVRILGFLE+EHRLFAQLLYGTGMRISEGLQLRVKDLDFDHGTIIVREGKGSKDRALML
Sbjct  121  EVVRILGFLESEHRLFAQLLYGTGMRISEGLQLRVKDLDFDHGTIIVREGKGSKDRALML  180

Query  181  PESLAPSLREQLSRARAWWLKDQAEGRSGVALPDALERKYPRAGHSW  227
            PESLAPSLREQLSRARAWWLKDQAEGRSGVALPDALERKYPRAGHSW
Sbjct  181  PESLAPSLREQLSRARAWWLKDQAEGRSGVALPDALERKYPRAGHSW  227

7) DIP1947 in NC_002935


> JF262175|4|G2|325301789|ADZ05801.1|Acinetobacter_baumannii_NIPH2554|-|1437..2118|intI1|-|integrase
Length=227

 Score =  288 bits (1077),  Expect = 1e-79, Method: Compositional matrix adjust.
 Identities = 193/205 (95%), Positives = 199/205 (98%), Gaps = 3/205 (1%)

Query  1    MKTATAPLPPLRSVKVLDQLRERIRYLHYSLRTEQAYVHWVRAFIRFHGVRHPATLGSSE  60
            MKTATAPLPPLRSVKVLDQLRERIRYLHYSLRTEQAYV+WVRAFIRFHGVRHPATLGSSE
Sbjct  1    MKTATAPLPPLRSVKVLDQLRERIRYLHYSLRTEQAYVNWVRAFIRFHGVRHPATLGSSE  60

Query  61   VEAFLSWLANERKVSVSTHRQALAALLFFYGKVLCTDLPWLQEIGrprpsrrlpvvltpD  120
            VEAFLSWLANERKVSVSTHRQALAALLFFYGKVLCTDLPWLQEIGRPRPSRRLPVVLTPD
Sbjct  61   VEAFLSWLANERKVSVSTHRQALAALLFFYGKVLCTDLPWLQEIGRPRPSRRLPVVLTPD  120

Query  121  EVVRILGFLEGEHRLFAQLLYGTGMRISEGLQLRVKDLDFDHGTIIVREGKGSKDRALML  180
            EVVRILGFLE+EHRLFAQLLYGTGMRISEGLQLRVKDLDFDHGTIIVREGKGSKDRALML
Sbjct  121  EVVRILGFLESEHRLFAQLLYGTGMRISEGLQLRVKDLDFDHGTIIVREGKGSKDRALML  180

Query  181  PESLAPSLREQLSRGLCCKDWRQSE  205
            PESLAPSLREQLSR+   + W+  +
Sbjct  181  PESLAPSLREQLSRA---RAWWLKD  202

8) azo3724 in NC_008702


> JF262175|4|G2|325301789|ADZ05801.1|Acinetobacter_baumannii_NIPH2554|-|1437..2118|intI1|-|integrase
Length=227

 Score =  209 bits (778),  Expect = 9e-56, Method: Compositional matrix adjust.
 Identities = 116/199 (59%), Positives = 161/199 (81%), Gaps = 0/199 (0%)

Query  1    MTAVRLLDQVRARIRYKHYSLGTEQQYVYWVRTFLRFHGVRHPREMGATEVEQFLSWLAT  60
            + +V++LDQ+R RIRY HYSL TEQ YV WVR+F+RFHGVRHP  +G++EVE FLSWLA 
Sbjct  11   LRSVKVLDQLRERIRYLHYSLRTEQAYVNWVRAFIRFHGVRHPATLGSSEVEAFLSWLAN  70

Query  61   DRKVAVSTHKQALSALLFLYRNVLGVDLPWLSEFERPKTPVRLPSVLSGEEVSALLDAME  120
            +RKV+VSTH+QAL+ALLF+Y +VL  DLPWL E+ RP+ + RLP VL+ +EV  +L+ +E
Sbjct  71   ERKVSVSTHRQALAALLFFYGKVLCTDLPWLQEIGRPRPSRRLPVVLTPDEVVRILGFLE  130

Query  121  GSNADLARLVYGTGMRLREALRLRVKDVDFQRRLIVVREGKGNKDRIVMLPHRCSNALRE  180
            + +  +A+L+YGTGMR+ E+L+LRVKD+DF++  I+VREGKG+KDR +MLP+  + +LRE
Sbjct  131  SEHRLFAQLLYGTGMRISEGLQLRVKDLDFDHGTIIVREGKGSKDRALMLPESLAPSLRE  190

Query  181  QLHRAYLLWAQDRADGTPG  199
            QL RA   W +D+A+G +G
Sbjct  191  QLSRARAWWLKDQAEGRSG  209

9) Pmen_3075 in NC_009439


> JF262175|4|G2|325301789|ADZ05801.1|Acinetobacter_baumannii_NIPH2554|-|1437..2118|intI1|-|integrase
Length=227

 Score =  190 bits (706),  Expect = 3e-50, Method: Compositional matrix adjust.
 Identities = 116/215 (54%), Positives = 162/215 (76%), Gaps = 2/215 (0%)

Query  6    RLLDQMRDRIRLKHYSIRTERVYCEWVKRFIRFHHYRHPQEMGAPEVEAFLTDLAVRRDV  65
            ++LDQ+R+RIR  HYS+RTE+ Y +WV+ FIRFH  RHP  +G++EVEAFL+ LA  R V
Sbjct  15   KVLDQLRERIRYLHYSLRTEQAYVNWVRAFIRFHGVRHPATLGSSEVEAFLSWLANERKV  74

Query  66   SASTQNQALAALLFLYKEVLALNLPWLSDIVRAKKPQRLPVVLSIDEVRRVLDELDGELW  125
            S ST+ QALAALLF+Y  VL  +LPWL +I R++ ++RLPVVL+ DEV R+L+ L++E +
Sbjct  75   SVSTHRQALAALLFFYGKVLCTDLPWLQEIGRPRPSRRLPVVLTPDEVVRILGFLESEHR  134

Query  126  LVCSLLYGTGMRLMEALRLRVKDVDFARHEILIRDGKGMKDRITMLPQRLEQPLRHHLAV  185
            L   LLYGTGMR+ E+L+LRVKD+DF +  I++R+GKG KDR  MLP+ L  +LR++L+ 
Sbjct  135  LFAQLLYGTGMRISEGLQLRVKDLDFDHGTIIVREGKGSKDRALMLPESLAPSLREQLSR  194

Query  186  VQAQHRVELAQGRGDVWLPFALARKYPNAPYEQGW  220
             +A    + A+GR++V LP AL RKYP A   ++W
Sbjct  195  ARAWWLKDQAEGRSGVALPDALERKYPRA--GHSW  227

10) DSC_01675 in NC_016147


> JF262175|4|G2|325301789|ADZ05801.1|Acinetobacter_baumannii_NIPH2554|-|1437..2118|intI1|-|integrase
Length=227

 Score =  182 bits (674),  Expect = 2e-47, Method: Compositional matrix adjust.
 Identities = 112/211 (54%), Positives = 159/211 (76%), Gaps = 0/211 (0%)

Query  1    MLEQVRRRLRAKHYSLRTEQAYVGWIRRFILANGKRHPRQLGAAEVETFLSALANEHAVA  60
            +L+Q+R R+R  HYSLRTEQAYV W+R FI  +G RHP  LG++EVE+FLS LANE+ V+
Sbjct  16   VLDQLRERIRYLHYSLRTEQAYVNWVRAFIRFHGVRHPATLGSSEVEAFLSWLANERKVS  75

Query  61   AGTQNQALAALLFLYREVLGDELPWLENLTRAKRPQRLPVVLSVEETRTLLACMDGRAWL  120
             +T+ QALAALLF+Y  VL  +LPWL+++ R++ ++RLPVVL+ +E   +L+ +++  +L
Sbjct  76   VSTHRQALAALLFFYGKVLCTDLPWLQEIGRPRPSRRLPVVLTPDEVVRILGFLESEHRL  135

Query  121  VASLLYGTGMRLMECLRLRVKDVDFTRGEITVRDGKGGKDRRTVLPRSLAEPLQREVERA  180
             A LLYGTGMR+ E L+LRVKD+DF +G I VR+GKG+KDR  +LP SLA +L+ ++ RA
Sbjct  136  FAQLLYGTGMRISEGLQLRVKDLDFDHGTIIVREGKGSKDRALMLPESLAPSLREQLSRA  195

Query  181  LLLHRRDVAQGHGHAWLPHALERKYPNANRE  211
                 +D A+G++   LP+ALERKYP A + 
Sbjct  196  RAWWLKDQAEGRSGVALPDALERKYPRAGHS  226

11) Rcas_2866 in NC_009767


> JF262175|4|G2|325301789|ADZ05801.1|Acinetobacter_baumannii_NIPH2554|-|1437..2118|intI1|-|integrase
Length=227

 Score =  162 bits (600),  Expect = 1e-41, Method: Compositional matrix adjust.
 Identities = 97/212 (46%), Positives = 149/212 (71%), Gaps = 0/212 (0%)

Query  1    MLDRVRQTLRRKHSSYRTEQAYVHWIKRFIFFHNKRHPAEMGAPEIEAFLTRLAVKENVA  60
            +LD++R+ +R  H S RTEQAYV+W++ FI FH  RHPA +G++E+EAFL++LA   +V+
Sbjct  16   VLDQLRERIRYLHYSLRTEQAYVNWVRAFIRFHGVRHPATLGSSEVEAFLSWLANERKVS  75

Query  61   ASTQNQALQSILFLYREVLRQPVEEPIHALRAKKPKRIPTVLTRQEVQQLFAHLSGARLL  120
             ST+ QAL ++LF+Y  VL   +    +  R++ ++R+P VLT +EV ++++ L + + L
Sbjct  76   VSTHRQALAALLFFYGKVLCTDLPWLQEIGRPRPSRRLPVVLTPDEVVRILGFLESEHRL  135

Query  121  MVRLLYGSGLRLMECLRLRVKDLDFPYQTITVRDGKGENDRVTVLPTSLVQPLQAHLEQV  180
              +LLYG+G+R+ E L+LRVKDLDF   TI VR+GKG +DR  +LP SL  +L+ +L + 
Sbjct  136  FAQLLYGTGMRISEGLQLRVKDLDFDHGTIIVREGKGSKDRALMLPESLAPSLREQLSRA  195

Query  181  RQQHEGDLAQGYGAVSLPDALARTYPHAEREW  212
            R     D A+G ++V+LPDAL R YP+A + W
Sbjct  196  RAWWLKDQAEGRSGVALPDALERKYPRAGHSW  227

12) Nwat_1933 in NC_014315


> JF262175|4|G2|325301789|ADZ05801.1|Acinetobacter_baumannii_NIPH2554|-|1437..2118|intI1|-|integrase
Length=227

 Score =  156 bits (576),  Expect = 7e-40, Method: Compositional matrix adjust.
 Identities = 90/215 (42%), Positives = 153/215 (72%), Gaps = 3/215 (1%)

Query  13   MPSTKSPTLLEDIRRIMRLKHYSLHTERSYCEWIKQFVKFHQLNERSALFENSEAKIETF  72
            +P+ +S  +L+++R  +R  HYSL+TE++Y +W++ F++FH + + ++L   + + +E+F
Sbjct  8    LPPLRSVKVLDQLRERIRYLHYSLRTEQAYVNWVRAFIRFHGVRHPATL---GSSEVEAF  64

Query  73   LSYLATERKVAPATQNQAMNALLFLYKQVLDMPLAKHIEAIRSKTSRHVPVVLSLDEVRQ  132
            LS LA ERKV+ +T+ QA+ ALLF+Y +VL   L+   E  R++ SR++PVVL+ DEV +
Sbjct  65   LSWLANERKVSVSTHRQALAALLFFYGKVLCTDLPWLQEIGRPRPSRRLPVVLTPDEVVR  124

Query  133  VLPRVEGVAQLAVKLLYGSGLRISEAVRLRVQDLDYDYQQITVRSGKGDKDRITPLSAAM  192
            +L  +E+  +L  +LLYG+G+RISE+++LRV+DLD+D   I VR GKG KDR   L+ ++
Sbjct  125  ILGFLESEHRLFAQLLYGTGMRISEGLQLRVKDLDFDHGTIIVREGKGSKDRALMLPESL  184

Query  193  IPLLQNHLEKVKAIHKQDLADGFGAVYLPYALAKN  227
             P L+++L + +A   +D A+G ++V LP AL ++
Sbjct  185  APSLREQLSRARAWWLKDQAEGRSGVALPDALERK  219