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Homologs of SAS0027 gene of NC_002953_R1

127

protein-level

Hit (GenBank Accn)

Product

Source Genome

Eval.

Ident.(%)

1) SAS0027
( YP_042160.1 )

type I restriction enzyme methylase

NC_002953
(Staphylococcus aureus MSSA476)

0.0

100

2) hsdM
( YP_006844716.1 )

type I restriction-modification system modification subunit

NC_018704
(Amphibacillus xylanus NBRC 15112)

0.0

3) SZO_04280
( YP_002743986.1 )

type I restriction enzyme methylase protein

NC_012470
(Streptococcus equi H70)

0.0

4) GWCH70_3442
( YP_002951343.1 )

N-6 DNA methylase

NC_012794
(Geobacillus sp. WCH70)

0.0

5) MmarC5_0641
( YP_001097168.1 )

N-6 DNA methylase

NC_009135
(Methanococcus maripaludis C5)

0.0

6) Mevan_0263
( YP_001322784.1 )

N-6 DNA methylase

NC_009634
(Methanococcus vannielii SB)

0.0

7) CLOST_1265
( YP_003936290.1 )

N-6 DNA methylase

NC_014614
(Clostridium sticklandii DSM 519)

3e-180

8) SELR_pSRC600080
( YP_005434666.1 )

putative N-6 DNA methylase

NC_017070
(Selenomonas ruminantium TAM6421)

4e-169

9) ELI_1148
( YP_003959099.1 )

hypothetical protein

NC_014624
(Eubacterium limosum KIST612)

2e-163

10) hsdM2
( YP_001621247.1 )

type I restriction enzyme, M protein

NC_010163
(Acholeplasma laidlawii PG-8A)

1e-162

11) Elen_0768
( YP_003181135.1 )

N-6 DNA methylase

NC_013204
(Eggerthella lenta DSM 2243)

1e-148

12) CLM_2296
( YP_002804464.1 )

N-6 DNA methylase

NC_012563
(Clostridium botulinum Kyoto)

2e-143

13) Synpcc7942_1060
( YP_400077.1 )

type I restriction-modification

NC_007604
(Synechococcus elongatus PCC 7942)

7e-131

14) syc0488_c
( YP_171198.1 )

type I restriction-modification

NC_006576
(Synechococcus elongatus PCC6301)

7e-131

15) Alvin_3259
( YP_003456900.1 )

N-6 DNA methylase

NC_013862
(Allochromatium vinosum DSM 180)

2e-126

16) Dole_0276
( YP_001528163.1 )

N-6 DNA methylase

NC_009943
(Desulfococcus oleovorans Hxd3)

7e-125

17) Shel_19060
( YP_003144271.1 )

type I restriction-modification system methyltransferase subunit

NC_013165
(Slackia heliotrinireducens DSM 20476)

4e-123

18) Dvul_0488
( YP_965938.1 )

N-6 DNA methylase

NC_008751
(Desulfovibrio vulgaris DP4)

4e-121

19) Nitsa_1299
( YP_004168299.1 )

n-6 DNA methylase

NC_014935
(Nitratifractor salsuginis DSM 16511)

1e-120

20) hsdM
( YP_931509.1 )

site-specific DNA-methyltransferase

NC_008702
(Azoarcus sp. BH72)

2e-120

21) hsdM
( YP_005146027.1 )

type I restriction enzyme M protein

NC_016790
(Corynebacterium diphtheriae VA01)

5e-119

22) C770_GR4Chr0590
( YP_007189161.1 )

Type I restriction-modification system methyltransferase subunit

NC_019845
(Sinorhizobium meliloti GR4)

2e-118

23) hsdM
( YP_005165950.1 )

type I restriction enzyme M protein

NC_016802
(Corynebacterium diphtheriae HC02)

3e-118

24) Rta_21410
( YP_004619256.1 )

type I restriction enzyme M protein

NC_015677
(Ramlibacter tataouinensis TTB310)

6e-118

25) hsdM-1
( YP_002795514.1 )

HsdM

NC_012559
(Laribacter hongkongensis HLHK9)

2e-117

26) hsdM3
( YP_005128658.1 )

type I restriction enzyme M protein

NC_016783
(Corynebacterium diphtheriae INCA 402)

2e-116

27) hsdM2
( YP_005143834.1 )

type I restriction enzyme M protein

NC_016789
(Corynebacterium diphtheriae PW8)

2e-116

28) Mspyr1_52870
( YP_004079646.1 )

type I restriction-modification system methyltransferase subunit

NC_014814
(Mycobacterium gilvum Spyr1)

2e-116

29) hsdM
( YP_708956.1 )

type I restriction-modification system methyltransferase subunit

NC_008271
(Rhodococcus jostii RHA1)

2e-114

30) Sgly_0845
( YP_004265195.1 )

N-6 DNA methylase

NC_015172
(Syntrophobotulus glycolicus DSM 8271)

4e-114

31) CC_0620
( NP_419437.1 )

type I restriction-modification system, M subunit

NC_002696
(Caulobacter crescentus CB15)

1e-113

32) CCNA_00656
( YP_002516029.1 )

type I restriction-modification system methylation subunit

NC_011916
(Caulobacter crescentus NA1000)

8e-114

33) Pnap_4916
( YP_973722.1 )

N-6 DNA methylase

NC_008759
(Polaromonas naphthalenivorans CJ2)

3e-113

34) hsdM
( NP_875100.1 )

type I restriction-modification system methyltransferase subunit

NC_005042
(Prochlorococcus marinus CCMP1375)

2e-112

35) Belba_0350
( YP_006405768.1 )

type I restriction-modification system methyltransferase subunit

NC_018010
(Belliella baltica DSM 15883)

4e-111

36) TepRe1_2225
( YP_004461654.1 )

N-6 DNA methylase

NC_015519
(Tepidanaerobacter acetatoxydans Re1)

1e-107

37) TepiRe1_2393
( YP_008619218.1 )

putative type I restriction-modification system DNA methylase (HsdM)

NC_019954
(Tepidanaerobacter acetatoxydans Re1)

1e-107

38) Mbar_A1016
( YP_304564.1 )

type I restriction-modification system methyltransferase subunit

NC_007355
(Methanosarcina barkeri Fusaro)

7e-107

39) SACTE_4308
( YP_004804683.1 )

N-6 DNA methylase

NC_015953
(Streptomyces sp. SirexAA-E)

1e-106

40) BpOF4_03735
( YP_003425705.1 )

N-6 DNA methylase (M) subunit of Type 1 restriction-modification system

NC_013791
(Bacillus pseudofirmus OF4)

7e-106

41) Clocl_0189
( YP_005044858.1 )

type I restriction-modification system methyltransferase subunit

NC_016627
(Clostridium clariflavum DSM 19732)

1e-105

42) CE0048
( NP_736658.1 )

restriction enzyme subunit S

NC_004369
(Corynebacterium efficiens YS-314)

3e-105

43) hsdM
( YP_003915183.1 )

type I restriction-modification system modification subunit

NC_014549
(Arthrobacter arilaitensis Re117)

6e-105

44) C624_04845
( YP_008065686.1 )

restriction enzyme subunit S

NC_021351
(Corynebacterium glutamicum SCgG1)

8e-105

45) C629_04845
( YP_008068709.1 )

restriction enzyme subunit S

NC_021352
(Corynebacterium glutamicum SCgG2)

8e-105

46) BTG_16390
( YP_006604753.1 )

N-6 DNA methylase (M) subunit of Type 1 restriction-modification system

NC_018500
(Bacillus thuringiensis HD-771)

8e-105

47) Nther_0795
( YP_001916970.1 )

N-6 DNA methylase

NC_010718
(Natranaerobius thermophilus JW/NM-WN-LF)

8e-105

48) B841_03910
( YP_008370752.1 )

restriction enzyme subunit S

NC_021915
(Corynebacterium maris DSM 45190)

2e-103

49) Turpa_0058
( YP_006438227.1 )

N-6 DNA methylase

NC_018020
(Turneriella parva DSM 21527)

4e-103

50) DGI_1296
( YP_008590318.1 )

putative N-6 DNA methylase

NC_022444
(Desulfovibrio gigas ATCC 19364)

2e-102

51) hsdM
( YP_006258661.1 )

Type I restriction-modification system methyltransferase subunit

NC_017771
(Deinococcus gobiensis I-0)

5e-102

52) NIES39_A06670
( YP_005067043.1 )

type I restriction-modification system M subunit

NC_016640
(Arthrospira platensis NIES-39)

6e-102

53) RBAU_0694
( YP_008411698.1 )

putative type I restriction-modification system DNA methylase (HsdM)

NC_022075
(Bacillus amyloliquefaciens UCMB-5033)

2e-101

54) Oscil6304_1092
( YP_007084739.1 )

type I restriction-modification system methyltransferase subunit

NC_019693
(Oscillatoria acuminata PCC 6304)

2e-101

55) Amir_0960
( YP_003098765.1 )

N-6 DNA methylase

NC_013093
(Actinosynnema mirum DSM 43827)

3e-101

56) hsdM
( YP_004522617.1 )

type I restriction/modification system DNA methylase HsdM

NC_015576
(Mycobacterium sp. JDM601)

4e-101

57) Francci3_0192
( YP_479312.1 )

N-6 DNA methylase

NC_007777
(Frankia sp. CcI3)

4e-101

58) BSUW23_03425
( YP_003865050.1 )

Type I restriction-modification system methyltransferase subunit (HsdM)

NC_014479
(Bacillus subtilis W23)

5e-101

59) I33_0764
( YP_005555736.1 )

type I restriction-modification system methyltransferase subunit

NC_017195
(Bacillus subtilis RO-NN-1)

1e-100

60) VAB18032_25315
( YP_004406761.1 )

N-6 DNA methylase

NC_015434
(Verrucosispora maris AB-18-032)

1e-100

61) Maqu_0234
( YP_957527.1 )

N-6 DNA methylase

NC_008740
(Marinobacter aquaeolei VT8)

3e-100

62) hsdM [C]
( YP_007216208.1 )

Type I restriction-modification system, DNA-methyltransferase subunit M

NC_019902
(Thioalkalivibrio nitratireducens DSM 14787)

3e-100

63) PSPA7_0075
( YP_001345471.1 )

N-6 DNA methylase

NC_009656
(Pseudomonas aeruginosa PA7)

3e-100

64) Hhal_1155
( YP_001002733.1 )

N-6 DNA methylase

NC_008789
(Halorhodospira halophila SL1)

5e-100

65) B005_4037
( YP_006643098.1 )

N-6 DNA Methylase family protein

NC_018524
(Nocardiopsis alba ATCC BAA-2165)

6e-100

66) PSTAA_0900
( YP_005937552.1 )

N-6 DNA methylase

NC_017532
(Pseudomonas stutzeri DSM 4166)

1e-99

67) BLASA_2167
( YP_005329106.1 )

Type I restriction-modification system methyltransferase subunit

NC_016943
(Blastococcus saxobsidens DD2)

2e-99

68) Maqu_0413
( YP_957703.1 )

N-6 DNA methylase

NC_008740
(Marinobacter aquaeolei VT8)

2e-99

69) PSF113_5184
( YP_005210559.1 )

Type I restriction-modification system, DNA-methyltransferase subunit M

NC_016830
(Pseudomonas fluorescens F113)

5e-99

70) Mycsm_01239
( YP_007291063.1 )

type I restriction-modification system methyltransferase subunit

NC_019966
(Mycobacterium smegmatis JS623)

5e-99

71) PST_0647
( YP_001171195.1 )

type I restriction-modification system, M subunit

NC_009434
(Pseudomonas stutzeri A1501)

4e-98

72) Psest_0874
( YP_007239097.1 )

type I restriction-modification system methyltransferase subunit

NC_019936
(Pseudomonas stutzeri RCH2)

1e-97

73) hsdM2
( YP_003850364.1 )

type I restriction-modification enzyme, subunit M

NC_014408
(Methanothermobacter marburgensis Marburg)

2e-97

74) Psest_3405
( YP_007241525.1 )

type I restriction-modification system methyltransferase subunit

NC_019936
(Pseudomonas stutzeri RCH2)

2e-97

75) Msil_1550
( YP_002361862.1 )

N-6 DNA methylase

NC_011666
(Methylocella silvestris BL2)

3e-97

76) Bcav_1495
( YP_002881513.1 )

N-6 DNA methylase

NC_012669
(Beutenbergia cavernae DSM 12333)

3e-97

77) K734_03215
( YP_008034144.1 )

Type I restriction-modification system methyltransferase subunit

NC_021286
(Idiomarina loihiensis GSL 199)

3e-97

78) hsdM
( YP_155032.1 )

Type I restriction-modification system methyltransferase subunit

NC_006512
(Idiomarina loihiensis L2TR)

3e-97

79) Nwat_0430
( YP_003759716.1 )

N-6 DNA methylase

NC_014315
(Nitrosococcus watsonii C-113)

8e-97

80) Tgr7_0604
( YP_002512687.1 )

type I restriction-modification system, M subunit; N-6 adenine-specific DNA methylase

NC_011901
(Thioalkalivibrio sulfidophilus HL-EbGR7)

1e-96

81) Saut_0167
( YP_003891228.1 )

N-6 DNA methylase

NC_014506
(Sulfurimonas autotrophica DSM 16294)

3e-96

82) Noc_2687
( YP_344670.1 )

N-6 DNA methylase

NC_007484
(Nitrosococcus oceani ATCC 19707)

3e-96

83) Mlab_0841
( YP_001030279.1 )

hypothetical protein

NC_008942
(Methanocorpusculum labreanum Z)

3e-96

84) PALO_04810
( YP_007870936.1 )

type I restriction-modification system methyltransferase subunit

NC_021064
(Propionibacterium avidum 44067)

4e-96

85) F750_6067
( YP_007862978.1 )

type I restriction-modification system DNA-methyltransferase subunit M

NC_021055
(Streptomyces sp. PAMC26508)

5e-96

86) Ksed_13670
( YP_003149160.1 )

type I restriction-modification system methyltransferase subunit

NC_013169
(Kytococcus sedentarius DSM 20547)

7e-96

87) hsdM1
( YP_008074442.1 )

type I restriction-modification system M subunit HsdM1

NC_021355
(Methanobrevibacter sp. AbM4)

1e-95

88) GYY_03180
( YP_004742258.1 )

type I restriction-modification enzyme, subunit M

NC_015847
(Methanococcus maripaludis X1)

2e-95

89) Metev_0463
( YP_003726174.1 )

N-6 DNA methylase

NC_014253
(Methanohalobium evestigatum Z-7303)

2e-95

90) Ksed_22800
( YP_003150022.1 )

type I restriction-modification system methyltransferase subunit

NC_013169
(Kytococcus sedentarius DSM 20547)

3e-95

91) B932_2648
( YP_006985130.1 )

N-6 DNA methylase

NC_019396
(Gluconobacter oxydans H24)

3e-95

92) CLOAM0217
( YP_001740333.1 )

Type I restriction-modification system methyltransferase subunit

NC_020449
(Candidatus Cloacamonas acidaminovorans Evry)

2e-94

93) PST_0252
( YP_001170801.1 )

type I restriction-modification system, M subunit

NC_009434
(Pseudomonas stutzeri A1501)

4e-94

94) SACE_0871
( YP_001103133.1 )

type I restriction-modification system methyltransferase subunit

NC_009142
(Saccharopolyspora erythraea NRRL 2338)

4e-94

95) Sfri_2608
( YP_751287.1 )

N-6 DNA methylase

NC_008345
(Shewanella frigidimarina NCIMB 400)

1e-93

96) LPC_2790
( YP_001252037.1 )

putative type I restriction enzyme M protein

NC_009494
(Legionella pneumophila Corby)

1e-92

97) Dd1591_4253
( YP_003006523.1 )

N-6 DNA methylase

NC_012912
(Dickeya zeae Ech1591)

2e-92

98) Tbd_2680
( YP_316438.1 )

type I restriction-modification system methyltransferase subunit

NC_007404
(Thiobacillus denitrificans ATCC 25259)

8e-92

99) Halru_2807
( YP_007285511.1 )

type I restriction-modification system methyltransferase subunit

NC_019964
(Halovivax ruber XH-70)

1e-91

100) Teth514_1222
( YP_001662852.1 )

N-6 DNA methylase

NC_010320
(Thermoanaerobacter sp. X514)

1e-91

101) PCC8801_3935
( YP_002374035.1 )

N-6 DNA methylase

NC_011726
(Cyanothece sp. PCC 8801)

4e-90

102) Cyan8802_3984
( YP_003139622.1 )

N-6 DNA methylase

NC_013161
(Cyanothece sp. PCC 8802)

4e-90

103) Tery_4473
( YP_723933.1 )

N-6 DNA methylase

NC_008312
(Trichodesmium erythraeum IMS101)

7e-90

104) Thimo_3451
( YP_007245746.1 )

type I restriction-modification system methyltransferase subunit

NC_019940
(Thioflavicoccus mobilis 8321)

2e-89

105) Metme_4216
( YP_004515066.1 )

N-6 DNA methylase

NC_015572
(Methylomonas methanica MC09)

4e-89

106) Mfla_2604
( YP_546710.1 )

N-6 DNA methylase

NC_007947
(Methylobacillus flagellatus KT)

9e-89

107) CtCNB1_1525
( YP_003277567.1 )

type I restriction-modification system subunit M

NC_013446
(Comamonas testosteroni CNB-1)

1e-88

108) KVU_PA0074
( YP_005796705.1 )

Type I restriction-modification system methyltransferase subunit

NC_017386
(Ketogulonicigenium vulgare WSH-001)

1e-88

109) EIO_2897
( YP_003944006.1 )

type I restriction-modification system methyltransferase subunit

NC_014621
(Ketogulonicigenium vulgare Y25)

1e-88

110) Despr_0254
( YP_004193731.1 )

N-6 DNA methylase

NC_014972
(Desulfobulbus propionicus DSM 2032)

2e-88

111) Halhy_2185
( YP_004446941.1 )

N-6 DNA methylase

NC_015510
(Haliscomenobacter hydrossis DSM 1100)

6e-88

112) Dacet_1462
( YP_003504188.1 )

N-6 DNA methylase

NC_013943
(Denitrovibrio acetiphilus DSM 12809)

1e-87

113) Dacet_1978
( YP_003504697.1 )

N-6 DNA methylase

NC_013943
(Denitrovibrio acetiphilus DSM 12809)

1e-87

114) SHJG_7917
( YP_006249057.1 )

N-6 DNA methylase

NC_017765
(Streptomyces hygroscopicus 5008)

4e-87

115) SHJGH_7679
( YP_007696675.1 )

N-6 DNA methylase

NC_020895
(Streptomyces hygroscopicus TL01)

4e-87

116) lpa_00829
( YP_003617806.1 )

hypothetical protein

NC_014125
(Legionella pneumophila 2300/99 Alcoy)

8e-87

117) SCIM_1266
( YP_006470168.1 )

hypothetical protein

NC_018073
(Streptococcus intermedius JTH08)

2e-86

118) SPPN_09370
( YP_004769145.1 )

N-6 DNA methylase

NC_015875
(Streptococcus pseudopneumoniae IS7493)

6e-86

119) Mhar_1859
( YP_005920839.1 )

type I restriction-modification system specificity subunit

NC_017527
(Methanosaeta harundinacea 6Ac)

6e-85

120) Cbei_3161
( YP_001310250.1 )

N-6 DNA methylase

NC_009617
(Clostridium beijerinckii NCIMB 8052)

1e-83

121) Dde_1861
( YP_388353.1 )

N-6 DNA methylase

NC_007519
(Desulfovibrio alaskensis G20)

2e-82

122) DESAM_20026
( YP_007324423.1 )

putative type I restriction-modification system (N6 DNA methylase)

NC_020055
(Desulfovibrio hydrothermalis DSM 14728)

3e-82

123) GM18_2924
( YP_004199644.1 )

N-6 DNA methylase

NC_014973
(Geobacter sp. M18)

4e-82

124) Atc_1133
( YP_004748482.1 )

type I restriction-modification methylase

NC_015850
(Acidithiobacillus caldus SM-1)

1e-79

125) NIDE1898
( YP_003797549.1 )

putative type I restriction system, N-6 adenine-specific DNA methylase HsdM

NC_014355
(Candidatus Nitrospira defluvii )

1e-79

126) Smon_0657
( YP_003306008.1 )

N-6 DNA methylase

NC_013515
(Streptobacillus moniliformis DSM 12112)

2e-78

127) Cphamn1_0751
( YP_001959185.1 )

N-6 DNA methylase

NC_010831
(Chlorobium phaeobacteroides BS1)

1e-77

• Sequence Alignments

1) SAS0027 in NC_002953


> NC_002953_R1|4|G3|49484939|YP_042160.1|Staphylococcus_aureus_subsp._aureus_MSSA476|-|4742..6529|-|SAS0027|type 
I restriction 
enzyme methylase
Length=595

 Score =  962 bits (3645),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 595/595 (100%), Positives = 595/595 (100%), Gaps = 0/595 (0%)

Query  1    MSEFKRHQQTSINVQKQANLIWNVADILRGLYKPHEYGKVILPMTVIKRLHDTLLKTRDK  60
            MSEFKRHQQTSINVQKQANLIWNVADILRGLYKPHEYGKVILPMTVIKRLHDTLLKTRDK
Sbjct  1    MSEFKRHQQTSINVQKQANLIWNVADILRGLYKPHEYGKVILPMTVIKRLHDTLLKTRDK  60

Query  61   VLKTAENTQSINDVMRERLLKNASGYSFYNTSLYTFETLLADPANIESNFRAYLNGFSEN  120
            VLKTAENTQSINDVMRERLLKNASGYSFYNTSLYTFETLLADPANIESNFRAYLNGFSEN
Sbjct  61   VLKTAENTQSINDVMRERLLKNASGYSFYNTSLYTFETLLADPANIESNFRAYLNGFSEN  120

Query  121  MQDILNNFKFDVEITTMADNDVLFYVIQEFNKADAYLGPDKMTSTDMGYVFEELVRKFSE  180
            MQDILNNFKFDVEITTMADNDVLFYVIQEFNKADAYLGPDKMTSTDMGYVFEELVRKFSE
Sbjct  121  MQDILNNFKFDVEITTMADNDVLFYVIQEFNKADAYLGPDKMTSTDMGYVFEELVRKFSE  180

Query  181  SYNEEAGAHFTSRDIIYLMTDLLLIEDKDTLFKEHVFKTVYDQTMGTSQMLSAMTERIHD  240
            SYNEEAGAHFTSRDIIYLMTDLLLIEDKDTLFKEHVFKTVYDQTMGTSQMLSAMTERIHD
Sbjct  181  SYNEEAGAHFTSRDIIYLMTDLLLIEDKDTLFKEHVFKTVYDQTMGTSQMLSAMTERIHD  240

Query  241  MNDTAEVATFGQELNPETYAISKADTMIRGGDPENMALGSTLTSDRFEGFTFDYCISNPP  300
            MNDTAEVATFGQELNPETYAISKADTMIRGGDPENMALGSTLTSDRFEGFTFDYCISNPP
Sbjct  241  MNDTAEVATFGQELNPETYAISKADTMIRGGDPENMALGSTLTSDRFEGFTFDYCISNPP  300

Query  301  FGVDWKKDQKAVKAEHELGELGRFGVGLPRVSDGQLLFQLNGISKLKETGRMAIIHNGSA  360
            FGVDWKKDQKAVKAEHELGELGRFGVGLPRVSDGQLLFQLNGISKLKETGRMAIIHNGSA
Sbjct  301  FGVDWKKDQKAVKAEHELGELGRFGVGLPRVSDGQLLFQLNGISKLKETGRMAIIHNGSA  360

Query  361  LFSGNPGAGESLIRQYVIENDWLEGIIQLPNDLFYNTGISTYIWIITKDKSPERQGKVQL  420
            LFSGNPGAGESLIRQYVIENDWLEGIIQLPNDLFYNTGISTYIWIITKDKSPERQGKVQL
Sbjct  361  LFSGNPGAGESLIRQYVIENDWLEGIIQLPNDLFYNTGISTYIWIITKDKSPERQGKVQL  420

Query  421  VDASNMYEKRRKNIGEKRVDISEACREMIVQAYGEFNDKEYYLGDGTVESKILKNESFGF  480
            VDASNMYEKRRKNIGEKRVDISEACREMIVQAYGEFNDKEYYLGDGTVESKILKNESFGF
Sbjct  421  VDASNMYEKRRKNIGEKRVDISEACREMIVQAYGEFNDKEYYLGDGTVESKILKNESFGF  480

Query  481  TRVTIERPQRDENGDIVYKKNGSKSVDTNLRDTEDIPLTEDINEYFEREILPFNQDAWMD  540
            TRVTIERPQRDENGDIVYKKNGSKSVDTNLRDTEDIPLTEDINEYFEREILPFNQDAWMD
Sbjct  481  TRVTIERPQRDENGDIVYKKNGSKSVDTNLRDTEDIPLTEDINEYFEREILPFNQDAWMD  540

Query  541  RKKDKIGYEIPFTRLFYKYTPPEPSEVISERIKQLEESIIKNFQALSGKEVDTNE  595
            RKKDKIGYEIPFTRLFYKYTPPEPSEVISERIKQLEESIIKNFQALSGKEVDTNE
Sbjct  541  RKKDKIGYEIPFTRLFYKYTPPEPSEVISERIKQLEESIIKNFQALSGKEVDTNE  595

2) hsdM in NC_018704


> NC_002953_R1|4|G3|49484939|YP_042160.1|Staphylococcus_aureus_subsp._aureus_MSSA476|-|4742..6529|-|SAS0027|type 
I restriction 
enzyme methylase
Length=595

 Score =  839 bits (3178),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 486/595 (82%), Positives = 551/595 (93%), Gaps = 0/595 (0%)

Query  1    MNEFNRNLQTSINVQRQANLIWSVADILRGLYKPHEYGKVILPMTVIKRLHDTLKPTRDA  60
            M+EF+R+ QTSINVQ+QANLIW+VADILRGLYKPHEYGKVILPMTVIKRLHDTL  TRD 
Sbjct  1    MSEFKRHQQTSINVQKQANLIWNVADILRGLYKPHEYGKVILPMTVIKRLHDTLLKTRDK  60

Query  61   VLNVAKKTENMNETMRNKMLTKASGYSFYNTNLYTFETLLADPANIETNFRAYLNGFSEN  120
            VL+ A +T+++N+ MR+++L +ASGYSFYNT+LYTFETLLADPANIE+NFRAYLNGFSEN
Sbjct  61   VLKTAENTQSINDVMRERLLKNASGYSFYNTSLYTFETLLADPANIESNFRAYLNGFSEN  120

Query  121  MQDILANFKFDLEISNLAENDRLFYVIQEFSKKEVDLGPDKMTSTDMGYVFEELVRKFSE  180
            MQDIL NFKFD+EI+ +A+ND LFYVIQEF+K +  LGPDKMTSTDMGYVFEELVRKFSE
Sbjct  121  MQDILNNFKFDVEITTMADNDVLFYVIQEFNKADAYLGPDKMTSTDMGYVFEELVRKFSE  180

Query  181  SYNEEAGAHFTSRDVIYLMTDLLLVEDQDTLTGKDVVKTVYDQTMGTSQMLSAMTERIHE  240
            SYNEEAGAHFTSRD+IYLMTDLLL+ED+DTL   +V KTVYDQTMGTSQMLSAMTERIH+
Sbjct  181  SYNEEAGAHFTSRDIIYLMTDLLLIEDKDTLFKEHVFKTVYDQTMGTSQMLSAMTERIHD  240

Query  241  MNESAEVATFGQELNPETYAIAKADTMIRGGNPDNMALGSTLSKDAFEGYTFDYCISNPP  300
            MN++AEVATFGQELNPETYAI+KADTMIRGG+P+NMALGSTL+ D FEG+TFDYCISNPP
Sbjct  241  MNDTAEVATFGQELNPETYAISKADTMIRGGDPENMALGSTLTSDRFEGFTFDYCISNPP  300

Query  301  FGIDWKSDQNAVKAEHELGENGRFGVGLPRISDGQLLFQLNGISKLKETGRMAIIHNGSA  360
            FG+DWK DQ+AVKAEHELGE GRFGVGLPR+SDGQLLFQLNGISKLKETGRMAIIHNGSA
Sbjct  301  FGVDWKKDQKAVKAEHELGELGRFGVGLPRVSDGQLLFQLNGISKLKETGRMAIIHNGSA  360

Query  361  LFSGNPGAGESLIRQYVIENDWLEAIVQLPNDLFYNTGISTYIWIITKNKTQERQGKVQL  420
            LFSGNPGAGESLIRQYVIENDWLE+I+QLPNDLFYNTGISTYIWIITK+K+ ERQGKVQL
Sbjct  361  LFSGNPGAGESLIRQYVIENDWLEGIIQLPNDLFYNTGISTYIWIITKDKSPERQGKVQL  420

Query  421  IDASKMFEKRRKNIGEKRVDISEECRDMIVKAYGEFTNDEYYLDERVVESKIFDNEEFGF  480
            +DAS+M+EKRRKNIGEKRVDISE CR+MIV+AYGEF + EYYL++  VESKI+ NE FGF
Sbjct  421  VDASNMYEKRRKNIGEKRVDISEACREMIVQAYGEFNDKEYYLGDGTVESKILKNESFGF  480

Query  481  TRVTVESPLKDENGEIERKKNGDPKPDPKLRDTEDIPLTEDIDDYFEREVLPFNPDAWMD  540
            TRVT+E P +DENG+I  KKNG    D +LRDTEDIPLTEDI++YFERE+LPFN DAWMD
Sbjct  481  TRVTIERPQRDENGDIVYKKNGSKSVDTNLRDTEDIPLTEDINEYFEREILPFNQDAWMD  540

Query  541  RSKDKIGYEIPFTRLFYKYTAPEPSEVIAERIKKLEESIVANFQALSGKDVENVD  595
            R KDKIGYEIPFTRLFYKYT+PEPSEVI+ERIK+LEESI+ NFQALSGK+V+  +
Sbjct  541  RKKDKIGYEIPFTRLFYKYTPPEPSEVISERIKQLEESIIKNFQALSGKEVDTNE  595

3) SZO_04280 in NC_012470


> NC_002953_R1|4|G3|49484939|YP_042160.1|Staphylococcus_aureus_subsp._aureus_MSSA476|-|4742..6529|-|SAS0027|type 
I restriction 
enzyme methylase
Length=595

 Score =  709 bits (2681),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 406/589 (69%), Positives = 500/589 (85%), Gaps = 3/589 (0%)

Query  11   RNERMTTNIKEKASLIWSIADILRGLYKPHEYGKVILPMTVIKRLHDTLLPTRDRVLEVS  70
            R+++ + N++ +A+LIW++ADILRGLYKPHEYGKVILPMTVIKRLHDTLL TRD+VL  +
Sbjct  6    RHQQTSINVQKQANLIWNVADILRGLYKPHEYGKVILPMTVIKRLHDTLLKTRDKVLKTA  65

Query  71   KTLSNIKVAQIRDRKLTDTSGYKFYNTSNFTFNSLLSDPDNIQENFYAFLNGFSENVRDI  130
                +I+   +R+R L ++SGY FYNTS +TF++LL+DP NI+ NF A+LNGFSEN++DI
Sbjct  66   ENTQSIN-DVMRERLLKNASGYSFYNTSLYTFETLLADPANIESNFRAYLNGFSENMQDI  124

Query  131  LDNFEFDEEISKMTNNDALFAVIQEFNSQKAYLGADTVTSTDMGYIFEELVRRFSESYGE  190
            L+NF FD EI+ M++ND LF VIQEFN   AYLG+D +TSTDMGY+FEELVR+FSESY E
Sbjct  125  LNNFKFDVEITTMADNDVLFYVIQEFNKADAYLGPDKMTSTDMGYVFEELVRKFSESYNE  184

Query  191  DAGAHFTSRDIIYLMTDILLIDEKPS--DKPIVRTIYDQTMGTSQMLSAMMERIKALDAN  248
            +AGAHFTSRDIIYLMTD+LLI++K +     + +T+YDQTMGTSQMLSAM ERI  ++  
Sbjct  185  EAGAHFTSRDIIYLMTDLLLIEDKDTLFKEHVFKTVYDQTMGTSQMLSAMTERIHDMNDT  244

Query  249  ADVTTFGQELNPETYAIAKADTMIRGGNPDNMALGSTLSKDAFSGYTFDYLISNPPFGID  308
            A+V+TFGQELNPETYAI+KADTMIRGG+P+NMALGSTL+ D F G+TFDY ISNPPFG+D
Sbjct  245  AEVATFGQELNPETYAISKADTMIRGGDPENMALGSTLTSDRFEGFTFDYCISNPPFGVD  304

Query  309  WKKDQKAVKEEAELGEKGRFGAGLPKISDGQLLFQLNGISKLKDTGRMAIIHNGSALFSG  368
            WKKDQKAVK E ELGE GRFG GLP++SDGQLLFQLNGISKLK+TGRMAIIHNGSALFSG
Sbjct  305  WKKDQKAVKAEHELGELGRFGVGLPRVSDGQLLFQLNGISKLKETGRMAIIHNGSALFSG  364

Query  369  NAGGGESAIREYVIMNDWLEAIIQLPTDLFYNTGISTYIWIITKNKVEERRGKVQLLDAS  428
            N+G+GES IR+YVI NDWLE+IIQLP DLFYNTGISTYIWIITK+K  ER+GKVQL+DAS
Sbjct  365  NPGAGESLIRQYVIENDWLEGIIQLPNDLFYNTGISTYIWIITKDKSPERQGKVQLVDAS  424

Query  429  RAFVKRRKNIGDKKVDIEKAQRELIVQAYGEFANQIYIEGDTAVESKIFDNNFFGYRKVV  488
              + KRRKNIG+K+VDI  A RE+IVQAYGEF ++ Y  GD +VESKI+ N+ FG+ +V 
Sbjct  425  NMYEKRRKNIGEKRVDISEACREMIVQAYGEFNDKEYYLGDGTVESKILKNESFGFTRVT  484

Query  489  VETPMYDEDGNIVRNKNGKATPDTSKRNTEDIPLTEDVDEYITREVLPFNPDAWVDDSKT  548
            +E P  DE+G+IV +KNG  + DT+ R+TEDIPLTED++EY+ RE+LPFN DAW+D  K 
Sbjct  485  IERPQRDENGDIVYKKNGSKSVDTNLRDTEDIPLTEDINEYFEREILPFNQDAWMDRKKD  544

Query  549  KIGYEIPFTRLFYKYQAPENSETIAKRIKELEEKIVKNFESLSGQDVEG  597
            KIGYEIPFTRLFYKY +PE SE I+ RIK+LEE I+KNF++LSG++V+ 
Sbjct  545  KIGYEIPFTRLFYKYTPPEPSEVISERIKQLEESIIKNFQALSGKEVDT  593

4) GWCH70_3442 in NC_012794


> NC_002953_R1|4|G3|49484939|YP_042160.1|Staphylococcus_aureus_subsp._aureus_MSSA476|-|4742..6529|-|SAS0027|type 
I restriction 
enzyme methylase
Length=595

 Score =  691 bits (2612),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 416/595 (70%), Positives = 511/595 (86%), Gaps = 3/595 (0%)

Query  1    MNEQRLHQQTGINIQEKANLIWSIADSLRGLYKPHQYGEVILPMTVIKRFHDTLLPTREK  60
            M+E + HQQT+IN+Q +ANLIW++AD LRGLYKPH+YG VILPMTVIKR+HDTLL TR+K
Sbjct  1    MSEFKRHQQTSINVQKQANLIWNVADILRGLYKPHEYGKVILPMTVIKRLHDTLLKTRDK  60

Query  61   VLETYEKVKHLE--VKEGFLQSASGYVFYNVSKFTFDSLLADPDNIEENFLAYLHGFSEN  118
            VL T E+ + ++  ++E +L++ASGY FYN S +TF++LLADP NIE NF AYL+GFSEN
Sbjct  61   VLKTAENTQSINDVMRERLLKNASGYSFYNTSLYTFETLLADPANIESNFRAYLNGFSEN  120

Query  119  VQDVLKNFDFEREVRRLADNDKLFYVIQEFNSEKAYLGPDKITSTDMGYIFEELIKKFSE  178
            +QD+L+NF F+ E+  +ADND LFYVIQEFN   AYLGPDK+TSTDMGY+FEEL++KFSE
Sbjct  121  MQDILNNFKFDVEITTMADNDVLFYVIQEFNKADAYLGPDKMTSTDMGYVFEELVRKFSE  180

Query  179  SYDEEAGSHFTSRDIIYLMTDLLIEEEKDVLMNEGIAKTVYDQTMGTSQMLSAMEERLKA  238
            SY+EEAG+HFTSRDIIYLMTDLL+ E+KD L +E + KTVYDQTMGTSQMLSAM ER+  
Sbjct  181  SYNEEAGAHFTSRDIIYLMTDLLLIEDKDTLFKEHVFKTVYDQTMGTSQMLSAMTERIHD  240

Query  239  LDPEAEVTVFGQEINEQTYAIAKADTMIRGGNPDNMRLGNTLTEDQFEGYTFDYCISNPP  298
            ++  AEV+ FGQE+N +TYAI+KADTMIRGG+P+NM LG+TLT D+FEG+TFDYCISNPP
Sbjct  241  MNDTAEVATFGQELNPETYAISKADTMIRGGDPENMALGSTLTSDRFEGFTFDYCISNPP  300

Query  299  FGVDWKSEYEKVKAEHEKGENGRFGVGLPKKNDGQllfllnglsklKDTGRMAIIHNGSA  358
            FGVDWK +   VKAEHE GE GRFGVGLP+ +DGQLLF LNG+SKLK+TGRMAIIHNGSA
Sbjct  301  FGVDWKKDQKAVKAEHELGELGRFGVGLPRVSDGQLLFQLNGISKLKETGRMAIIHNGSA  360

Query  359  LFSGDAGSGESEIRRYVIENDWLEAIVQLPADLFYNTGITTYIWILTKNKPKHRIGKVQL  418
            LFSG++G+GES IR+YVIENDWLE+I+QLP DLFYNTGI+TYIWI+TK+K+ +R GKVQL
Sbjct  361  LFSGNPGAGESLIRQYVIENDWLEGIIQLPNDLFYNTGISTYIWIITKDKSPERQGKVQL  420

Query  419  IDASNMYEKRRKNIGNKRVDITEPCREMIVKAYREFLNKEYRMGERTVESKIFDNEDFGY  478
            +DASNMYEKRRKNIG+KRVDI+E+CREMIV+AY EF +KEY +G+ TVESKI+ NE FG+
Sbjct  421  VDASNMYEKRRKNIGEKRVDISEACREMIVQAYGEFNDKEYYLGDGTVESKILKNESFGF  480

Query  479  YKVTVETPQYDEDGNIV-MKNGKPVPDKDKRDTEEIPLKEDIQEYFEREIKPFNPDAWID  537
             +VT+E PQ DE+G+IV  KNG    D + RDTE+IPL EDI+EYFEREI PFN DAW+D
Sbjct  481  TRVTIERPQRDENGDIVYKKNGSKSVDTNLRDTEDIPLTEDINEYFEREILPFNQDAWMD  540

Query  538  ENKTKIGYEIPFTRLFYKFQPPEKSEDIAVRIRKLEEEIVKSFESLSGEVVKKDE  592
             +K KIGYEIPFTRLFYK+ PPE SE I+ RI++LEE I+K+F++LSG  V  +E
Sbjct  541  RKKDKIGYEIPFTRLFYKYTPPEPSEVISERIKQLEESIIKNFQALSGKEVDTNE  595

5) MmarC5_0641 in NC_009135


> NC_002953_R1|4|G3|49484939|YP_042160.1|Staphylococcus_aureus_subsp._aureus_MSSA476|-|4742..6529|-|SAS0027|type 
I restriction 
enzyme methylase
Length=595

 Score =  659 bits (2492),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 367/589 (63%), Positives = 496/589 (85%), Gaps = 11/589 (1%)

Query  6    HQTNINVQEKANMIWNIADIIRGTFKPHEYGKVILPMTVLKRLNDTLLPTKDAVLKTCEE  65
            +QT+INVQ +AN+IWN+ADI+RG +KPHEYGKVILPMTV+KRL+DTLL T+D VLKT E+
Sbjct  8    QQTSINVQKQANLIWNVADILRGLYKPHEYGKVILPMTVIKRLHDTLLKTRDKVLKTAEN  67

Query  66   IKDFE--VKEGFLESAAGYPFYNTSPFTFETLLNDPDHIEANFRKFIAGFSDNIQDIIKH  123
             + ++  ++E +L +A+GY+FYNTS +TFETLL DP +IE+NFR ++ GFS+N+QDI+++
Sbjct  68   TQSINDVMRERLLKNASGYSFYNTSLYTFETLLADPANIESNFRAYLNGFSENMQDILNN  127

Query  124  FKFEHIISDLVGSTPEEDKLFYVIQEFNKPSSYMGPDAISTADMGYIFEELIRKFSESYN  183
            FKF+  I+ +    +++D LFYVIQEFNK+ +Y+GPD ++++DMGY+FEEL+RKFSESYN
Sbjct  128  FKFDVEITTM----ADNDVLFYVIQEFNKADAYLGPDKMTSTDMGYVFEELVRKFSESYN  183

Query  184  EEAGAHFTARDIIYLMTDLLVTEDE---FDGSP-KTCYDMAMGTSQMLTCLTERIQQLDN  239
            EEAGAHFT+RDIIYLMTDLL+ ED    F     KT YD +MGTSQML+ +TERI+++++
Sbjct  184  EEAGAHFTSRDIIYLMTDLLLIEDKDTLFKEHVFKTVYDQTMGTSQMLSAMTERIHDMND  243

Query  240  KIEVSVFGQEFNPETFAIAKADMIIRGGKADNMRFGDTLINDQFKGYTFDYCISNPPFGV  299
              EV+ FGQE+NPET+AI+KAD +IRGG ++NM +G TL +D+F G+TFDYCISNPPFGV
Sbjct  244  TAEVATFGQELNPETYAISKADTMIRGGDPENMALGSTLTSDRFEGFTFDYCISNPPFGV  303

Query  300  DWKAQKKAVDKENKLAEKGRFGVGLPKISDGQMLFTLNGISKLKDTGRLAIIHNGSPLFT  359
            DWK ++KAV  E+ L+E GRFGVGLP++SDGQ+LF LNGISKLK+TGR+AIIHNGS+LF+
Sbjct  304  DWKKDQKAVKAEHELGELGRFGVGLPRVSDGQLLFQLNGISKLKETGRMAIIHNGSALFS  363

Query  360  GDAGSGPSEIRKYIIENDWLDAIVQLPNDLFYNTGITTYVWLISKNKSDERAGKVQLIDA  419
            G++G+G S IR+Y+IENDWL++I+QLPNDLFYNTGI+TY+W+I+K+KS ER GKVQL+DA
Sbjct  364  GNPGAGESLIRQYVIENDWLEGIIQLPNDLFYNTGISTYIWIITKDKSPERQGKVQLVDA  423

Query  420  SNMYVKRRKSIGNKRVDLSTDCREAIVKAYGEFSDKYYDYGEKSVESKVFNNEDFGYYKI  479
            SNMY KRRK+IG+KRVD+S  CRE IV+AYGEF+DK Y  G+ +VESK+++NE FG+ ++
Sbjct  424  SNMYEKRRKNIGEKRVDISEACREMIVQAYGEFNDKEYYLGDGTVESKILKNESFGFTRV  483

Query  480  TVESPLKDEKGKIVIKK-GKPAPDTSKRDTENVPLTEDIEEYFKREVLPYNPEAWIDDKK  538
            T+E P +DE+G IV KK G  + DT+ RDTE++PLTEDI+EYF RE+LP+N +AW+D KK
Sbjct  484  TIERPQRDENGDIVYKKNGSKSVDTNLRDTEDIPLTEDINEYFEREILPFNQDAWMDRKK  543

Query  539  TTIGYEIPFTRHFYKYVAPEKSDMVAERICVIEAELTGSLKSLFGKDGE  587
              IGYEIPFTR FYKY +PE S++++ERI  +E  +  ++++L GK+ +
Sbjct  544  DKIGYEIPFTRLFYKYTPPEPSEVISERIKQLEESIIKNFQALSGKEVD  592

6) Mevan_0263 in NC_009634


> NC_002953_R1|4|G3|49484939|YP_042160.1|Staphylococcus_aureus_subsp._aureus_MSSA476|-|4742..6529|-|SAS0027|type 
I restriction 
enzyme methylase
Length=595

 Score =  652 bits (2465),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 364/589 (62%), Positives = 491/589 (84%), Gaps = 9/589 (1%)

Query  6    HKTNVNVSEKANMIWNIADIIRGTFKPHEYGKVILPMTVLKRLNDTLLPTKEKVLEAYKE  65
            ++T++NV  +AN+IWN+ADI+RG +KPHEYGKVILPMTV+KRL+DTLL T++KVL +  +
Sbjct  8    QQTSINVQKQANLIWNVADILRGLYKPHEYGKVILPMTVIKRLHDTLLKTRDKVLKTAEN  67

Query  66   YGSLE--VNDGFFRDASGYPFYNTSPFTFETLLNDPDHIEENFRTFMAGFSENIQDILKN  123
              S++  + + ++++ASGY+FYNTS +TFETLL DP +IE NFR+++ GFSEN+QDIL+N
Sbjct  68   TQSINDVMRERLLKNASGYSFYNTSLYTFETLLADPANIESNFRAYLNGFSENMQDILNN  127

Query  124  FKFEHIISDLVGSTAEDDKLFYVIQEFNKPNSYMGPDAISTADMGYIFEELIRKFSESYN  183
            FKF+  I+ +    A++D LFYVIQEFNK+++Y+GPD ++++DMGY+FEEL+RKFSESYN
Sbjct  128  FKFDVEITTM----ADNDVLFYVIQEFNKADAYLGPDKMTSTDMGYVFEELVRKFSESYN  183

Query  184  EEAGAHFTARDIIYLMTDLLVTEEDAALTRGKI--DCYDMAMGTSQMLTCLTERILQLDS  241
            EEAGAHFT+RDIIYLMTDLL+ E+  +L +  +    YD +MGTSQML+ +TERI +++ 
Sbjct  184  EEAGAHFTSRDIIYLMTDLLLIEDKDTLFKEHVFKTVYDQTMGTSQMLSAMTERIHDMND  243

Query  242  EVEVNVFGQEFNPETFAIAKADMIIRGGIADNMRFGDTLTNDQFKGYKFDYCISNPPFGV  301
              EV  FGQE+NPET+AI+KAD +IRGG ++NM +G TLT+D+F G+ FDYCISNPPFGV
Sbjct  244  TAEVATFGQELNPETYAISKADTMIRGGDPENMALGSTLTSDRFEGFTFDYCISNPPFGV  303

Query  302  EWKPQKNAVEKEHKSGDNGRFGVGLPKISDGQMLFTLNGISKLKDTGRMAIIHNGSPLFT  361
            +WK +++AV  EH  G+ GRFGVGLP++SDGQ+LF LNGISKLK+TGRMAIIHNGS+LF+
Sbjct  304  DWKKDQKAVKAEHELGELGRFGVGLPRVSDGQLLFQLNGISKLKETGRMAIIHNGSALFS  363

Query  362  GDAGSGPSEIRKYIIENDWLDAIVQLPNDLFYNTGITTYVWLISKNKSDERKGKVQLIDA  421
            G++G+G S IR+Y+IENDWL++I+QLPNDLFYNTGI+TY+W+I+K+KS ER+GKVQL+DA
Sbjct  364  GNPGAGESLIRQYVIENDWLEGIIQLPNDLFYNTGISTYIWIITKDKSPERQGKVQLVDA  423

Query  422  SNMYEKRRKSIGNKRVDLSEDCRAAIVQAYGEFTDKFYDYGDKSVESKVFNNEDFGFYKI  481
            SNMYEKRRK+IG+KRVD+SE CR  IVQAYGEF DK Y  GD +VESK+++NE FGF ++
Sbjct  424  SNMYEKRRKNIGEKRVDISEACREMIVQAYGEFNDKEYYLGDGTVESKILKNESFGFTRV  483

Query  482  TIESPLLDEKGKIV-MKKGKPAPDTSKRDTENVPLTDNIKNYFEREVLPYNPDAWVDESK  540
            TIE P  DE+G IV  K+G  + DT+ RDTE++PLT++I++YFERE+LP+N DAW+D  K
Sbjct  484  TIERPQRDENGDIVYKKNGSKSVDTNLRDTEDIPLTEDINEYFEREILPFNQDAWMDRKK  543

Query  541  TVIGYEIPFTRHFYKYVAPEKSDAIAERICVIEAELTGSLKSLFGKDGE  589
              IGYEIPFTR FYKY +PE S+ I+ERI  +E  +  ++++L GK+ +
Sbjct  544  DKIGYEIPFTRLFYKYTPPEPSEVISERIKQLEESIIKNFQALSGKEVD  592

7) CLOST_1265 in NC_014614


> NC_002953_R1|4|G3|49484939|YP_042160.1|Staphylococcus_aureus_subsp._aureus_MSSA476|-|4742..6529|-|SAS0027|type 
I restriction 
enzyme methylase
Length=595

 Score =  625 bits (2361),  Expect = 3e-180, Method: Compositional matrix adjust.
 Identities = 347/590 (59%), Positives = 481/590 (82%), Gaps = 13/590 (2%)

Query  5    QRQTNINVQEKADMIWGIADIIRGTFKPHEYGKVILPMTLLKRLNDTLLETKEGVLKKYE  64
            ++QT+INVQ +A++IW +ADI+RG +KPHEYGKVILPMT++KRL+DTLL T++ VLK  E
Sbjct  7    HQQTSINVQKQANLIWNVADILRGLYKPHEYGKVILPMTVIKRLHDTLLKTRDKVLKTAE  66

Query  65   EVKNFE--VKDGFLTKASGYSFYNISPFTFENLLNEPEHIEENFKTFIAGFSENIHDIIK  122
            + ++++  +++ +L +ASGYSFYN S +TFE LL +P +IE NF++++ GFSEN++DI++
Sbjct  67   NTQSINDVMRERLLKNASGYSFYNTSLYTFETLLADPANIESNFRAYLNGFSENMQDILN  126

Query  123  NFKFENTLNDLVGSTKEESKLFYVIQEFNKPNAYMGADIITTTDMGYIFEELVRKFSESY  182
            NFKF+  +  +     ++  LFYVIQEFNK++AY+G+D +T+TDMGY+FEELVRKFSESY
Sbjct  127  NFKFDVEITTMA----DNDVLFYVIQEFNKADAYLGPDKMTSTDMGYVFEELVRKFSESY  182

Query  183  NEEAGAHFTARDIIYTMTDLLIAEEENVLQEDGLVKTVYDMAMGTSQMLTSMEERLKELD  242
            NEEAGAHFT+RDIIY MTDLL+ E+ + L  + + KTVYD +MGTSQML++M ER+ +++
Sbjct  183  NEEAGAHFTSRDIIYLMTDLLLIEDKDTLFKEHVFKTVYDQTMGTSQMLSAMTERIHDMN  242

Query  243  ADAEVTVFGQEINPETYAIAKADMIIRGGNASNMRFGDTLSNDRFEDYEFDYIISNPPFG  302
              AEV+ FGQE+NPETYAI+KAD +IRGG++ NM +G TL++DRFE++ FDY ISNPPFG
Sbjct  243  DTAEVATFGQELNPETYAISKADTMIRGGDPENMALGSTLTSDRFEGFTFDYCISNPPFG  302

Query  303  VDWKAQKSAVEKEHKKGSNGRFAPGLPKISDGQMLFTLNGIKKLNDTGKMAIIHNGSPLF  362
            VDWK ++ AV  EH  G  GRF+ GLP++SDGQ+LF LNGI KL++TG+MAIIHNGS+LF
Sbjct  303  VDWKKDQKAVKAEHELGELGRFGVGLPRVSDGQLLFQLNGISKLKETGRMAIIHNGSALF  362

Query  363  VGDAGSGPSEIRRYIIENDLLEAIVQLPTDLFYNTGITTYIWLISKNKSARRTGKVQLID  422
             G++G+G S IR+Y+IEND LE+I+QLP DLFYNTGI+TYIW+I+K+KS+ R GKVQL+D
Sbjct  363  SGNPGAGESLIRQYVIENDWLEGIIQLPNDLFYNTGISTYIWIITKDKSPERQGKVQLVD  422

Query  423  ASNMYIKRRTSLGNKRVELDECCREAIVNAYGDFENKHYEYDKKSVESKIFNNEDFGYYK  482
            ASNMY KRR ++G+KRV++ E CRE IV+AYG+F++K+Y  +  +VESKI++NE FG+ +
Sbjct  423  ASNMYEKRRKNIGEKRVDISEACREMIVQAYGEFNDKEYYLGDGTVESKILKNESFGFTR  482

Query  483  IVVESPQVDEYGKIILKKKQS-VADPSKRDTENVPMILGKDQDEVIKEYFEKEVLPYNQD  541
            + +E PQ DE G I+ KK+ S   D + RDTE++P+       E I+EYFE+E+LP+NQD
Sbjct  483  VTIERPQRDENGDIVYKKNGSKSVDTNLRDTEDIPLT------EDINEYFEREILPFNQD  536

Query  542  AWVDENKTKIGYEIPFTRHFYKYVAPEKSEVIAERISAIENDLMGSLKSL  591
            AW+D +K KIGYEIPFTR FYKY +PE SEVI+ERI  +E+ ++ ++++L
Sbjct  537  AWMDRKKDKIGYEIPFTRLFYKYTPPEPSEVISERIKQLEESIIKNFQAL  586

8) SELR_pSRC600080 in NC_017070


> NC_002953_R1|4|G3|49484939|YP_042160.1|Staphylococcus_aureus_subsp._aureus_MSSA476|-|4742..6529|-|SAS0027|type 
I restriction 
enzyme methylase
Length=595

 Score =  588 bits (2221),  Expect = 4e-169, Method: Compositional matrix adjust.
 Identities = 330/586 (57%), Positives = 454/586 (78%), Gaps = 8/586 (1%)

Query  8    KIQEVGRNIQEKAALVWSVADDLVGAFKPHEYGLVVLPMAVIKRFHDCLLPTHERVLAKY  67
            + Q+ + N+Q +A L+W+VAD L G +KPHEYG V+LPM+VIKR+HD LL T+++VL   
Sbjct  6    RHQQTSINVQKQANLIWNVADILRGLYKPHEYGKVILPMTVIKRLHDTLLKTRDKVLKTA  65

Query  68   EEVKNLA--VKEGFLRGASGYQFYNTSPFTFKTLVADPENIEDNFKAYLNGFSDNVLDIL  125
            E+ +++   ++E +L+ ASGY FYNTS +TF TL+ADP NIE NF+AYLNGFS+N+ DIL
Sbjct  66   ENTQSINDVMRERLLKNASGYSFYNTSLYTFETLLADPANIESNFRAYLNGFSENMQDIL  125

Query  126  ARMDFTSQINRMVEGGLLYQVISDFNSEKADFSPENVTAVDMGYIFENLVQRFSESYNEE  185
                F  +I  M + ++L+ VI +FN   A ++P+++T+ DMGY+FE+LV++FSESYNEE
Sbjct  126  NNFKFDVEITTMADNDVLFYVIQEFNKADAYLGPDKMTSTDMGYVFEELVRKFSESYNEE  185

Query  186  AGAHFTSRDIIYLMCDLLVAGDRNAFEEDGISKTVYDMTMGTSQMLTCMEERLKALDSEA  245
            AGAHFTSRDIIYLM DLL+  D++++  + + KTVYD TMGTSQML+ M ER+  ++  A
Sbjct  186  AGAHFTSRDIIYLMTDLLLIEDKDTLFKEHVFKTVYDQTMGTSQMLSAMTERIHDMNDTA  245

Query  246  DVDVFGQEFNPFTFGIAKADMLIRGGDPDNMQFGDTLSDDKFSGYEFDYIISNPPFGIPW  305
            +V  FGQE+NP T++I+KAD +IRGGDP+NM +G TL+ D+F G+ FDY ISNPPFG+ W
Sbjct  246  EVATFGQELNPETYAISKADTMIRGGDPENMALGSTLTSDRFEGFTFDYCISNPPFGVDW  305

Query  306  KREENEVTAEHKQGAAGRFAPGLPAKSDGQMLFLLNGVAKLKENGRMAIIQNGSSLFTGD  365
            K++++ V AEH  G  GRF+ GLP  SDGQ+LF LNG++KLKE GRMAII+NGS+LF+G+
Sbjct  306  KKDQKAVKAEHELGELGRFGVGLPRVSDGQLLFQLNGISKLKETGRMAIIHNGSALFSGN  365

Query  366  AGSGQSEIRRYLIENDWLDAIVQLPNDSFYNTGIATYVWLITKDKPEERAGKVQLIDASN  425
            +G+G+S IR+Y+IENDWL++I+QLPND FYNTGI+TY+W+ITKDK+ ER GKVQL+DASN
Sbjct  366  PGAGESLIRQYVIENDWLEGIIQLPNDLFYNTGISTYIWIITKDKSPERQGKVQLVDASN  425

Query  426  CKVSRRKNIGNKRVDITTACRDLIVKLYGLYADGTFTETDENDGEITVKSKVLDAVTLGY  485
                RRKNIG+KRVDI+ ACR++IV+ Y     G F + +   G+ TV SK+L   ++G+
Sbjct  426  MYEKRRKNIGEKRVDISEACREMIVQAY-----GEFNDKEYYLGDGTVESKILKNESFGF  480

Query  486  NKITVESPELDENGEKVLKK-GKPVADTKKRDTENVPLEEDIDAYFEREVLPYNPDAWID  544
             ++T+E P+ DENG+ V KK G    DT+ RDTE++PL EDI+ YFERE+LP+N DAW+D
Sbjct  481  TRVTIERPQRDENGDIVYKKNGSKSVDTNLRDTEDIPLTEDINEYFEREILPFNQDAWMD  540

Query  545  RKKTKVGYEIPFTRTFYEYKQIEPAEDIAKRIEEHEKSLMSKLHEL  590
            RKK K+GYEIPFTR FY Y   EP+E I+ RI + E S++ +++ L
Sbjct  541  RKKDKIGYEIPFTRLFYKYTPPEPSEVISERIKQLEESIIKNFQAL  586

9) ELI_1148 in NC_014624


> NC_002953_R1|4|G3|49484939|YP_042160.1|Staphylococcus_aureus_subsp._aureus_MSSA476|-|4742..6529|-|SAS0027|type 
I restriction 
enzyme methylase
Length=595

 Score =  569 bits (2149),  Expect = 2e-163, Method: Compositional matrix adjust.
 Identities = 328/594 (56%), Positives = 445/594 (75%), Gaps = 14/594 (2%)

Query  10   VGTNIQEKANLIWNVANSLFGAYKPHEYGLVILPMVVIKRFHDCLLPTREKVLATYEKVK  69
             + N+Q +ANLIWNVA+ L G YKPHEYG VILPM VIKR+HD LL TR+KVL T E+ +
Sbjct  10   TSINVQKQANLIWNVADILRGLYKPHEYGKVILPMTVIKRLHDTLLKTRDKVLKTAENTQ  69

Query  70   QLA--VKDGFLRTASGYRFYNTSQYTFERLKADPENIKTNFEAYINGFSDNVIDILANMG  127
             +   +++ +L+ ASGY FYNTS YTFE L ADP NI +NF AY+NGFS+N+ DIL N  
Sbjct  70   SINDVMRERLLKNASGYSFYNTSLYTFETLLADPANIESNFRAYLNGFSENMQDILNNFK  129

Query  128  FFTQIERMADAGVLYQVISDFTADNADMNPEKISAIDMGYVFENLVQCFSESYDEEAGAH  187
            F  +I  MAD +VL+ VI +F   +A + P+K+++ DMGYVFE+LV+ FSESY+EEAGAH
Sbjct  130  FDVEITTMADNDVLFYVIQEFNKADAYLGPDKMTSTDMGYVFEELVRKFSESYNEEAGAH  189

Query  188  FTSRDIIYLMCDLLTMNAD---FSGEDAPAKTVYDMAMGTSQMLTCMEERVHALDKEAEI  244
            FTSRDIIYLM DLL ++     F   +   KTVYD +MGTSQML+ M ER+H ++  AE+
Sbjct  190  FTSRDIIYLMTDLLLIEDKDTLFK--EHVFKTVYDQTMGTSQMLSAMTERIHDMNDTAEV  247

Query  245  ICYGQEINPFTFGIAKADMLIRGGDPENMQFGDTLNADKFKGYTFDYIISNPPFGIDWKR  304
              +GQE+NP T++I+KAD +IRGGDPENM +G TL +D+F G+TFDY ISNPPFG+DWK+
Sbjct  248  ATFGQELNPETYAISKADTMIRGGDPENMALGSTLTSDRFEGFTFDYCISNPPFGVDWKK  307

Query  305  EAADVEKEHKLGDAGRFGVGLPQKSDGQMLFLLNGIAKLKDTGRMAIIQNGSSLFTGDAG  364
            +   V  EH LG+ GRFGVGLP+ SDGQ+LF LNGI+KLK+TGRMAII+NGS+LF+G++G
Sbjct  308  DQKAVKAEHELGELGRFGVGLPRVSDGQLLFQLNGISKLKETGRMAIIHNGSALFSGNPG  367

Query  365  SGPSEIRRYIIENDWLDAIVQLPNDSFYNTGIATYIWIVSKNKPETHRERILLIDASKCC  424
            +G S IR+Y+IENDWL++I+QLPND FYNTGI+TYIWI++K+K+  ++ ++ L+DAS+  
Sbjct  368  AGESLIRQYVIENDWLEGIIQLPNDLFYNTGISTYIWIITKDKSPERQGKVQLVDASNMY  427

Query  425  EARRRPIGNKRVDITESCRNLITQAYSEYRSAIFTKTLEDKKTVLTCKSKVLDAISLGYN  484
            E RR+ IG+KRVDI+E+CR++I QAY+E+    +   L D     T  SK+L   S+G+ 
Sbjct  428  EKRRKNIGEKRVDISEACREMIVQAYGEFNDKEY--YLGDG----TVESKILKNESFGFT  481

Query  485  KITVESPALDDDGNPIVKK-GKPVADTSKRDTESVPLDEDVDAYFAREVLPYRPGAWIDK  543
            ++T+E P  D++G+ + KK G    DT+ RDTE +PL ED++ YF RE+LP+  +AW+D+
Sbjct  482  RVTIERPQRDENGDIVYKKNGSKSVDTNLRDTEDIPLTEDINEYFEREILPFNQDAWMDR  541

Query  544  SKTKVGYEIPFTRTFYEYEELEPAADIAKRIAAREKVLMEKLQALFGNGGEQNE  597
             K K+GYEIPFTR FY Y   EP+  I+ RI   E  ++ ++QAL G+  + NE
Sbjct  542  KKDKIGYEIPFTRLFYKYTPPEPSEVISERIKQLEESIIKNFQALSGKEVDTNE  595

10) hsdM2 in NC_010163


> NC_002953_R1|4|G3|49484939|YP_042160.1|Staphylococcus_aureus_subsp._aureus_MSSA476|-|4742..6529|-|SAS0027|type 
I restriction 
enzyme methylase
Length=595

 Score =  567 bits (2139),  Expect = 1e-162, Method: Compositional matrix adjust.
 Identities = 331/585 (57%), Positives = 452/585 (78%), Gaps = 5/585 (0%)

Query  10   TTTNIQEKANLIWAIANHLVGLFKPHEYGKVILPMTVLKRFDDALKETKQEVLSLNKKLN  69
            T+ N+Q +ANLIW +A+ L GL+KPHEYGKVILPMTV+KR++D+L  T++ VL      N
Sbjct  10   TSINVQKQANLIWNVADILRGLYKPHEYGKVILPMTVIKRLHDTLLKTRDKVLKTAE--N  67

Query  70   EQKTIDAIKDGLICKTTGYDFYNVSPFTFENLLADPDNIASNFDTYLKGFSDNVKDIISN  129
             Q   D +++ L+ +++GY FYN S +TFE LLADP NI SNF +YL+GFS+N++DI++N
Sbjct  68   TQSINDVMRERLLKNASGYSFYNTSLYTFETLLADPANIESNFRAYLNGFSENMQDILNN  127

Query  130  FKFEQVLETMHKGNVLYVVIQEFNSKKADMHPDKITSMDMGYIFEELIRKFSESYDEQAG  189
            FKF+  + TM   +VL+ VIQEFN   A + PDK+TS DMGY+FEEL+RKFSESY+E+AG
Sbjct  128  FKFDVEITTMADNDVLFYVIQEFNKADAYLGPDKMTSTDMGYVFEELVRKFSESYNEEAG  187

Query  190  AHFTSRDIIYLMAELLVANEKEHIKQNGVVKTAYDMAMGTSQMLGCLDEKMKEINFDSKL  249
            AHFTSRDIIYLM++LL+ ++K+ + ++ V KT YD +MGTSQML+ + E++ ++N  + +
Sbjct  188  AHFTSRDIIYLMTDLLLIEDKDTLFKEHVFKTVYDQTMGTSQMLSAMTERIHDMNDTAEV  247

Query  250  SLFGQEFNPETYAIAKADMLIKGGNAQNMKFGDTLSDDQFSNYEFDYIISNPPFGIDWKL  309
            + FGQE+NPETYAI+KAD +I+GG+++NM +G TL+ D+F  + FDY ISNPPFG+DWK 
Sbjct  248  ATFGQELNPETYAISKADTMIRGGDPENMALGSTLTSDRFEGFTFDYCISNPPFGVDWKK  307

Query  310  EEKQVKQEYAKLGYDGRFGPGLPAISDGQMLFLLNGVKKLKEGSGRMAIIQNGSSLFTGD  369
            ++K VK E   LG  GRFG GLP +SDGQ+LF LNG+ KLKE +GRMAII+NGS+LF+G+
Sbjct  308  DQKAVKAEHE-LGELGRFGVGLPRVSDGQLLFQLNGISKLKE-TGRMAIIHNGSALFSGN  365

Query  370  AGSGPSEIRKYLIESDLLEAIIQLPTDLFYNTGISTYVWIVSKNKNKERLGKIQLIDASN  429
            +G+G S IR+Y+IE+D LE+IIQLP DLFYNTGISTY+WI++K+K+ ER GK+QL+DASN
Sbjct  366  PGAGESLIRQYVIENDWLEGIIQLPNDLFYNTGISTYIWIITKDKSPERQGKVQLVDASN  425

Query  430  CYVKRRKNIGKKRVDLDDTSIDLITKAYLDFKEVKYEENDLVVESKIFDNDFFGYTKVTV  489
             Y KRRKNIG KRVD+ ++  ++I +AY +F++  Y   D  VESKI+ N+ FG+T+VT+
Sbjct  426  MYEKRRKNIGEKRVDISEACREMIVQAYGEFNDKEYYLGDGTVESKILKNESFGFTRVTI  485

Query  490  ESPITDENGKPILKK-GKLQADSKKRDTELVPLQENIEAFFKDNVLPYNSSAWMDRSKDK  548
            E P  DENG  + KK G    D++ RDTE +PL E+I+ +F  ++LP+N  AWMDR KDK
Sbjct  486  ERPQRDENGDIVYKKNGSKSVDTNLRDTEDIPLTEDINEYFEREILPFNQDAWMDRKKDK  545

Query  549  VGYEIPFTRLFYKFIPPKASSDIFAEIKQLEEEETQLMKELFGNE  593
            +GYEIPFTRLFYK+ PP +S  I   IKQLEE   +  + L G+E
Sbjct  546  IGYEIPFTRLFYKYTPPEPSEVISERIKQLEESIIKNFQALSGKE  590

11) Elen_0768 in NC_013204


> NC_002953_R1|4|G3|49484939|YP_042160.1|Staphylococcus_aureus_subsp._aureus_MSSA476|-|4742..6529|-|SAS0027|type 
I restriction 
enzyme methylase
Length=595

 Score =  520 bits (1962),  Expect = 1e-148, Method: Compositional matrix adjust.
 Identities = 291/594 (49%), Positives = 436/594 (74%), Gaps = 14/594 (2%)

Query  13   QKRVDTPTFGTLPWNVADTLRGPYKPHEYGLVILPMTVIKRFHDCLLPTHGKVVEAAEEY  72
            Q  ++    + L WNVAD LRG YKPHEYG VILPMTVIKR+HD LL T++KV+ +AE+ 
Sbjct  9    QTSINVQKQANLIWNVADILRGLYKPHEYGKVILPMTVIKRLHDTLLKTRDKVLKTAENT  68

Query  73   KNFA--VKDGFLREASGYPFYNTSKFTFETLKADPANIEDNFKDYLNGFSENVQDILARM  130
            +++   +++ +L++ASGY+FYNTS +TFETL ADPANIE NF+ YLNGFSEN+QDIL   
Sbjct  69   QSINDVMRERLLKNASGYSFYNTSLYTFETLLADPANIESNFRAYLNGFSENMQDILNNF  128

Query  131  DFFRQIERLSDPDAPLLYQVVSDFCAERADMSPEKIKPVDMGYIFENLIQRFSESYDEDA  190
             F  ++E  + +D  +L+ V+ +F    A ++P+K+ + DMGY+FE+L+++FSESY+E+A
Sbjct  129  KF--DVEITTMADNDVLFYVIQEFNKADAYLGPDKMTSTDMGYVFEELVRKFSESYNEEA  186

Query  191  GAHFTSRDIVYLMTDLLIAADPHVFDGDRISKTVYDQTMGTSQMLSCTEERLRQLDDDAR  250
            GAHFTSRDI+YLMTDLL+  D + +  +++ KTVYDQTMGTSQMLS   ER+++++D A 
Sbjct  187  GAHFTSRDIIYLMTDLLLIEDKDTLFKEHVFKTVYDQTMGTSQMLSAMTERIHDMNDTAE  246

Query  251  VTCFGQEFNPFTFGIAKASALIRGEDDANMRFGDTLSSDKFADYKFDYCISNPPFGGDWK  310
            V+ FGQE+NP T++I+KA ++IRG D  NM +G TL+SD+F ++ FDYCISNPPFG DWK
Sbjct  247  VATFGQELNPETYAISKADTMIRGGDPENMALGSTLTSDRFEGFTFDYCISNPPFGVDWK  306

Query  311  LEETAVRKEAKLTG-SRFHVGLPARGDGQMLFMLNGIAKLKDEGVMVIVQDASPLYKGKP  369
             ++ AV+ E  L   +RF VGLP  +DGQ+LF LNGI+KLK+ G M I++++S+L+ G+P
Sbjct  307  KDQKAVKAEHELGELGRFGVGLPRVSDGQLLFQLNGISKLKETGRMAIIHNGSALFSGNP  366

Query  370  ESGEDKIRSYILENDWLDAIIRLSGDAFYNTGLVTFLWVINKGKPEKRAGKVQLIDASGC  429
             +GE  IR Y++ENDWL++II+L+ D FYNTG+ T++W+I K+K+  R GKVQL+DAS  
Sbjct  367  GAGESLIRQYVIENDWLEGIIQLPNDLFYNTGISTYIWIITKDKSPERQGKVQLVDASNM  426

Query  430  CVPRNRPIGKKRNDITKFCRDLVLEAFSDFETKDYSSSSESGNAIHVRSLVCDAADFGYN  489
               R + IG KR DI+  CR+++++A+++F+ K+Y  +  + ++  +++       FG+ 
Sbjct  427  YEKRRKNIGEKRVDISEACREMIVQAYGEFNDKEYYLGDGTVESKILKN-----ESFGFT  481

Query  490  RVGVCEPLFNPDGSIVVDKKGSPVADAEREDTEDIPLSYDIDEYMEKKVLPFNEHAWLNR  549
            RV +  P  + +G IV  K+GS   D++  DTEDIPL+ DI+EY E+ +LPFN++AW++R
Sbjct  482  RVTIERPQRDENGDIVYKKNGSKSVDTNLRDTEDIPLTEDINEYFEREILPFNQDAWMDR  541

Query  550  KKQKTGYTIPFTRFFYEFMDLETVNDAAQELSCSMNRSAAEVGRRFAMLPDPEI  603
            KK+K GY IPFTR+FY +    T  ++++ +S  +++    + + F  L++ E+
Sbjct  542  KKDKIGYEIPFTRLFYKY----TPPEPSEVISERIKQLEESIIKNFQALSGKEV  591

12) CLM_2296 in NC_012563


> NC_002953_R1|4|G3|49484939|YP_042160.1|Staphylococcus_aureus_subsp._aureus_MSSA476|-|4742..6529|-|SAS0027|type 
I restriction 
enzyme methylase
Length=595

 Score =  502 bits (1895),  Expect = 2e-143, Method: Compositional matrix adjust.
 Identities = 279/554 (51%), Positives = 420/554 (76%), Gaps = 13/554 (2%)

Query  6    NINEKANLIWAIADKLTGVYKPHEYGEVILPLTVIRRFDCVLADTKESVLKKNEQVGNLP  65
            N++ +ANLIW +AD L G+YKPHEYG VILP+TVI+R++  L  T++ VLK  E+  ++ 
Sbjct  13   NVQKQANLIWNVADILRGLYKPHEYGKVILPMTVIKRLHDTLLKTRDKVLKTAENTQSIN  72

Query  66   --MKDVFLCKEAGYDFYNISKFDFQKLLSDPDGIEANFRVYINGFSENVRNIIEKFNFDN  123
              M++ +L + +GY FYN S + F+ LL+DP  IE+NFR Y+NGFSEN+++I+++F+FD 
Sbjct  73   DVMRERLLKNASGYSFYNTSLYTFETLLADPANIESNFRAYLNGFSENMQDILNNFKFDV  132

Query  124  QITRLAEKNLLYIVIQEFVTPNADLHPSKISNLEMGYIFEEIIRRFSEAHNEDAGQHYTP  183
            +IT +A++++L+ VIQEF  ++A L P K+++ +MGY+FEE++R+FSE+ NE+AG H+T+
Sbjct  133  EITTMADNDVLFYVIQEFNKADAYLGPDKMTSTDMGYVFEELVRKFSESYNEEAGAHFTS  192

Query  184  REVIELMVNILFYNDSE-LLTGNIAKTIYDPACGTGGMLSVAEDYLKKLNKDAELIAFGQ  242
            R++I LM ++L+ +D + L+  ++ KT+YD + GT+ MLS   + +  +N  AE+ +FGQ
Sbjct  193  RDIIYLMTDLLLIEDKDTLFKEHVFKTVYDQTMGTSQMLSAMTERIHDMNDTAEVATFGQ  252

Query  243  EINDQTYAICKADMLIKGANADNIKNGNTLSDDQFKEDRYDYILSNPPFGREWKNDKKAV  302
            E+N +TYAI KAD +I+G++++N+  G+TL+ D+F    +DY +SNPPFG +WK+D+KAV
Sbjct  253  ELNPETYAISKADTMIRGGDPENMALGSTLTSDRFEGFTFDYCISNPPFGVDWKKDQKAV  312

Query  303  ETEAKLGFAGRFGAGVPAVGDGQMLFLETAIAKMKPQGSRIAIIHNGSPLFTGDAGSGPS  362
             +E  LG  GRFG G+P V+DGQ+LF   +I+K+K + +R+AIIHNGS+LF+G++G+G S
Sbjct  313  KAEHELGELGRFGVGLPRVSDGQLLFQLNGISKLK-ETGRMAIIHNGSALFSGNPGAGES  371

Query  363  EIRRYILENDLLEAIIALPNDIFYNTGIATYIWVLSNKKPDYRKGKVQLINANGLYEKRR  422
             IR+Y++END LE+II LPND+FYNTGI+TYIW++++ K+  R+GKVQL++A+ +YEKRR
Sbjct  372  LIRQYVIENDWLEGIIQLPNDLFYNTGISTYIWIITKDKSPERQGKVQLVDASNMYEKRR  431

Query  423  KSLGNKRNDIPKEYIDEITKLYGEFKKSE--------ISKIFDNKDFGYSKIVVERPKLK  474
            K++G+KR DI+    + I + YGEF+  E         SKI+ N  FG++++ +ERP+  
Sbjct  432  KNIGEKRVDISEACREMIVQAYGEFNDKEYYLGDGTVESKILKNESFGFTRVTIERPQRD  491

Query  475  EDGTPELKK-GKPVTDTSLRDTENVPLKEDINEYFKREVIPFAPDAWIDEKKTKVGYEIP  533
            E+G    KK G    DT+LRDTE++PL EDINEYF RE++PF  DAW+D KK K+GYEIP
Sbjct  492  ENGDIVYKKNGSKSVDTNLRDTEDIPLTEDINEYFEREILPFNQDAWMDRKKDKIGYEIP  551

Query  534  FTRYFYKYVPPKPA  547
            FTR FYKY PP P+
Sbjct  552  FTRLFYKYTPPEPS  565

13) syc0488_c in NC_006576


> NC_002953_R1|4|G3|49484939|YP_042160.1|Staphylococcus_aureus_subsp._aureus_MSSA476|-|4742..6529|-|SAS0027|type 
I restriction 
enzyme methylase
Length=595

 Score =  461 bits (1737),  Expect = 7e-131, Method: Compositional matrix adjust.
 Identities = 270/582 (47%), Positives = 416/582 (72%), Gaps = 15/582 (2%)

Query  99   QNLSAFIWSVADLLRGDYKQSDYGKIILPFTVLRRLDCVLAPTKAAVLEEKVLRES-QGL  157
            Q+ + +IW+VAD+LRG YK  +YGK+ILP TV++RL+  L  T+  VL      +S +++
Sbjct  15   QKQANLIWNVADILRGLYKPHEYGKVILPMTVIKRLHDTLLKTRDKVLKTAENTQSINDV  74

Query  158  APEPFLLKKAGQNFCNTSPLDLKQLMGDADNIGENLRAYIQGFTPAVRDIFDSFEFHLQI  217
              E +L + +G +F NTS   +  L++D+ NI  N+RAY++GF+  ++DI+++F F+++I
Sbjct  75   MRERLLKNASGYSFYNTSLYTFETLLADPANIESNFRAYLNGFSENMQDILNNFKFDVEI  134

Query  218  DRLEKAGLLYLVTERFAQID--LHPDTVSNAEMGLVFEELIRKFAELSNETAGEHFTPRE  275
              +   ++L+ V + F + D  L PD +++++MG VFEEL+RKF+E  NE AG HFT+R+
Sbjct  135  TTMADNDVLFYVIQEFNKADAYLGPDKMTSTDMGYVFEELVRKFSESYNEEAGAHFTSRD  194

Query  276  VIRLMVNLLFIEDDAALTQPGIVRSLYDPTAGTGGMLSVAEEHLTELNPSARLVLSGQEL  335
            +I LM +LL+IED  +L +  + +++YD T GT+ MLS   E++ ++N +A +   GQEL
Sbjct  195  IIYLMTDLLLIEDKDTLFKEHVFKTVYDQTMGTSQMLSAMTERIHDMNDTAEVATFGQEL  254

Query  336  NPESYAICKADMLIKGQNIQNICFGNTLSDDKLPDAKYDYMLSNPPFGVEWKKIQKEVQR  395
            NPE+YAI KAD +I+G + +N+ +G+TL+ D++ +  +DY +SNPPFGV+WKK QK V +
Sbjct  255  NPETYAISKADTMIRGGDPENMALGSTLTSDRFEGFTFDYCISNPPFGVDWKKDQKAV-K  313

Query  396  EAEQLGYSGRFGPGLPRVSDGSLLFLLHLISKMRPASEGGSRLGIVLNGSPLFTGGAGSG  455
              ++LG  GRFG GLPRVSDG LLF L+ ISK++ +    +R++I+ NGS+LF+G +G+G
Sbjct  314  AEHELGELGRFGVGLPRVSDGQLLFQLNGISKLKET----GRMAIIHNGSALFSGNPGAG  369

Query  456  ESEIRRYVLENDLVEAIIALPTDMFYNTGISTYIWILSNRKPASRKGKVQLIDASGFWQK  515
            ES IR+YV+END +E+II LP D+FYNTGISTYIWI+++ K++ R+GKVQL+DAS   +K
Sbjct  370  ESLIRQYVIENDWLEGIIQLPNDLFYNTGISTYIWIITKDKSPERQGKVQLVDASNMYEK  429

Query  516  MRKSLGSKRKELSEEQIAEITRLFGNFEEAD---RDGKPVSKIFRNEEFGYRTITVERPQ  572
             RK++G KR ++SE     I + +G+F++ +    DG   SKI++NE FG+  +T+ERPQ
Sbjct  430  RRKNIGEKRVDISEACREMIVQAYGEFNDKEYYLGDGTVESKILKNESFGFTRVTIERPQ  489

Query  573  RDEAGNVVLAQRGKTKGQPVADASLRDTENVPLTEDVDTYFQREVLPHVPDAWIDPEKTK  632
            RDE G++V     K +G    D++LRDTE++PLTED++ YF+RE+LP   DAW+D  K K
Sbjct  490  RDENGDIVY----KKNGSKSVDTNLRDTEDIPLTEDINEYFEREILPFNQDAWMDRKKDK  545

Query  633  VGYEIPFNRHFYVFTPPRSLEEIDAELQQVTDRILTMLGGLS  674
            +GYEIPF R FY +TPP + E I   ++Q+ + I+  + +LS
Sbjct  546  IGYEIPFTRLFYKYTPPEPSEVISERIKQLEESIIKNFQALS  587

14) Synpcc7942_1060 in NC_007604


> NC_002953_R1|4|G3|49484939|YP_042160.1|Staphylococcus_aureus_subsp._aureus_MSSA476|-|4742..6529|-|SAS0027|type 
I restriction 
enzyme methylase
Length=595

 Score =  461 bits (1737),  Expect = 7e-131, Method: Compositional matrix adjust.
 Identities = 270/582 (47%), Positives = 416/582 (72%), Gaps = 15/582 (2%)

Query  99   QNLSAFIWSVADLLRGDYKQSDYGKIILPFTVLRRLDCVLAPTKAAVLEEKVLRES-QGL  157
            Q+ + +IW+VAD+LRG YK  +YGK+ILP TV++RL+  L  T+  VL      +S +++
Sbjct  15   QKQANLIWNVADILRGLYKPHEYGKVILPMTVIKRLHDTLLKTRDKVLKTAENTQSINDV  74

Query  158  APEPFLLKKAGQNFCNTSPLDLKQLMGDADNIGENLRAYIQGFTPAVRDIFDSFEFHLQI  217
              E +L + +G +F NTS   +  L++D+ NI  N+RAY++GF+  ++DI+++F F+++I
Sbjct  75   MRERLLKNASGYSFYNTSLYTFETLLADPANIESNFRAYLNGFSENMQDILNNFKFDVEI  134

Query  218  DRLEKAGLLYLVTERFAQID--LHPDTVSNAEMGLVFEELIRKFAELSNETAGEHFTPRE  275
              +   ++L+ V + F + D  L PD +++++MG VFEEL+RKF+E  NE AG HFT+R+
Sbjct  135  TTMADNDVLFYVIQEFNKADAYLGPDKMTSTDMGYVFEELVRKFSESYNEEAGAHFTSRD  194

Query  276  VIRLMVNLLFIEDDAALTQPGIVRSLYDPTAGTGGMLSVAEEHLTELNPSARLVLSGQEL  335
            +I LM +LL+IED  +L +  + +++YD T GT+ MLS   E++ ++N +A +   GQEL
Sbjct  195  IIYLMTDLLLIEDKDTLFKEHVFKTVYDQTMGTSQMLSAMTERIHDMNDTAEVATFGQEL  254

Query  336  NPESYAICKADMLIKGQNIQNICFGNTLSDDKLPDAKYDYMLSNPPFGVEWKKIQKEVQR  395
            NPE+YAI KAD +I+G + +N+ +G+TL+ D++ +  +DY +SNPPFGV+WKK QK V +
Sbjct  255  NPETYAISKADTMIRGGDPENMALGSTLTSDRFEGFTFDYCISNPPFGVDWKKDQKAV-K  313

Query  396  EAEQLGYSGRFGPGLPRVSDGSLLFLLHLISKMRPASEGGSRLGIVLNGSPLFTGGAGSG  455
              ++LG  GRFG GLPRVSDG LLF L+ ISK++ +    +R++I+ NGS+LF+G +G+G
Sbjct  314  AEHELGELGRFGVGLPRVSDGQLLFQLNGISKLKET----GRMAIIHNGSALFSGNPGAG  369

Query  456  ESEIRRYVLENDLVEAIIALPTDMFYNTGISTYIWILSNRKPASRKGKVQLIDASGFWQK  515
            ES IR+YV+END +E+II LP D+FYNTGISTYIWI+++ K++ R+GKVQL+DAS   +K
Sbjct  370  ESLIRQYVIENDWLEGIIQLPNDLFYNTGISTYIWIITKDKSPERQGKVQLVDASNMYEK  429

Query  516  MRKSLGSKRKELSEEQIAEITRLFGNFEEAD---RDGKPVSKIFRNEEFGYRTITVERPQ  572
             RK++G KR ++SE     I + +G+F++ +    DG   SKI++NE FG+  +T+ERPQ
Sbjct  430  RRKNIGEKRVDISEACREMIVQAYGEFNDKEYYLGDGTVESKILKNESFGFTRVTIERPQ  489

Query  573  RDEAGNVVLAQRGKTKGQPVADASLRDTENVPLTEDVDTYFQREVLPHVPDAWIDPEKTK  632
            RDE G++V     K +G    D++LRDTE++PLTED++ YF+RE+LP   DAW+D  K K
Sbjct  490  RDENGDIVY----KKNGSKSVDTNLRDTEDIPLTEDINEYFEREILPFNQDAWMDRKKDK  545

Query  633  VGYEIPFNRHFYVFTPPRSLEEIDAELQQVTDRILTMLGGLS  674
            +GYEIPF R FY +TPP + E I   ++Q+ + I+  + +LS
Sbjct  546  IGYEIPFTRLFYKYTPPEPSEVISERIKQLEESIIKNFQALS  587

15) Alvin_3259 in NC_013862


> NC_002953_R1|4|G3|49484939|YP_042160.1|Staphylococcus_aureus_subsp._aureus_MSSA476|-|4742..6529|-|SAS0027|type 
I restriction 
enzyme methylase
Length=595

 Score =  446 bits (1681),  Expect = 2e-126, Method: Compositional matrix adjust.
 Identities = 279/580 (49%), Positives = 414/580 (72%), Gaps = 15/580 (2%)

Query  7    SALIWSVADLLRGDYKQSDYGKVILPFTVLRRLDCVLESTKDAVL-AEEKAKRQMGVNPE  65
            + LIW+VAD+LRG YK  +YGKVILP TV++RL+  L  T+D VL + E+++   +V  E
Sbjct  18   ANLIWNVADILRGLYKPHEYGKVILPMTVIKRLHDTLLKTRDKVLKTAENTQSINDVMRE  77

Query  66   LFLLRVSGQSFYNVSPLDMKKLLGDPDHIKANLLSYLHGFSDDVRDIFEQFDVQTQIDRL  125
             +L   SG SFYN S      LL+DP +I +N+ +YL+GFS++++DI+++F  + +I  +
Sbjct  78   RLLKNASGYSFYNTSLYTFETLLADPANIESNFRAYLNGFSENMQDILNNFKFDVEITTM  137

Query  126  AKTNLLYQVTERFAQVD--LHPNRVSNSQMGLVFEELIRKFAELSNETAGEHFTPREVIR  183
            A  ++L+ V + F + D  L P+++++++MG VFEEL+RKF+E  NE AG HFT+R++I 
Sbjct  138  ADNDVLFYVIQEFNKADAYLGPDKMTSTDMGYVFEELVRKFSESYNEEAGAHFTSRDIIY  197

Query  184  LMVNLLFIEDDAVLAKPGVVRTLYDPTAGTGGMLSVAGEYLEEHNPEARLTMFGQELNPE  243
            LM +LL+IED   L K  V +T+YD T GT+ MLS   E +++ N  A ++ FGQELNPE
Sbjct  198  LMTDLLLIEDKDTLFKEHVFKTVYDQTMGTSQMLSAMTERIHDMNDTAEVATFGQELNPE  257

Query  244  SYAICKADMLIKGQDVANIVFGNTFSEDGHPQRTFDYMLSNPPFGVEWKKVEKAIRQEHE  303
            +YAI KAD +I+G D  N+ +G+T++ D     TFDY +SNPPFGV+WKK +KA++ EHE
Sbjct  258  TYAISKADTMIRGGDPENMALGSTLTSDRFEGFTFDYCISNPPFGVDWKKDQKAVKAEHE  317

Query  304  TLGFSGRFGPGLPRVSDGSLLFLLHLISKMRPAIDGGSRLGIVLNGSPLFTGGAGSGESE  363
             LG  GRFG GLPRVSDG LLF L+ ISK++ +    +R++I+ NGS+LF+G +G+GES 
Sbjct  318  -LGELGRFGVGLPRVSDGQLLFQLNGISKLKET----GRMAIIHNGSALFSGNPGAGESL  372

Query  364  IRRYVLENDLVEAIIGLPTDMFYNTGISTYVWILSNRKPEHRRGLVQLIDASGLWQKMRK  423
            IR+YV+END +E+II LP D+FYNTGISTY+WI+++ K+ +R+G VQL+DAS + +K RK
Sbjct  373  IRQYVIENDWLEGIIQLPNDLFYNTGISTYIWIITKDKSPERQGKVQLVDASNMYEKRRK  432

Query  424  SLGSKRKELSDAHIAEITRLFGEC--REAYDGKKPI-SRLFKNSDFGYRTITVERPLRDE  480
            ++G KR ++S+A    I + +GE   +E Y G   + S+++KN  FG+  +T+ERP RDE
Sbjct  433  NIGEKRVDISEACREMIVQAYGEFNDKEYYLGDGTVESKILKNESFGFTRVTIERPQRDE  492

Query  481  AGNIVlglkgkqkgkpqpDTSRRDTENVPLAEDVETYFQREVLPHAQDAWIDHDKTKVGY  540
             G+IV     K++G    DT+ RDTE++PL+ED++ YF+RE+LP  QDAW+D+ K K+GY
Sbjct  493  NGDIV----YKKNGSKSVDTNLRDTEDIPLTEDINEYFEREILPFNQDAWMDRKKDKIGY  548

Query  541  EIPFNRHFYVFEPPRPLADIDADLKRCTDRILTMIEGLSA  580
            EIPF R FY + PP P   I   +K+  + I+  +++LS+
Sbjct  549  EIPFTRLFYKYTPPEPSEVISERIKQLEESIIKNFQALSG  588

16) Dole_0276 in NC_009943


> NC_002953_R1|4|G3|49484939|YP_042160.1|Staphylococcus_aureus_subsp._aureus_MSSA476|-|4742..6529|-|SAS0027|type 
I restriction 
enzyme methylase
Length=595

 Score =  441 bits (1660),  Expect = 7e-125, Method: Compositional matrix adjust.
 Identities = 271/565 (48%), Positives = 400/565 (71%), Gaps = 15/565 (2%)

Query  5    QDKANFIWQVADDILRGTFKQHEYGDVILPFVVFRRLDCVLNGKKDEIIDTYKKFQKKLD  64
            Q +AN+IW+VAD ILRG +K HEYG VILP  V++RL+  L   +D ++ T  + Q   D
Sbjct  15   QKQANLIWNVAD-ILRGLYKPHEYGKVILPMTVIKRLHDTLLKTRDKVLKTAENTQSIND  73

Query  65   DPSAVVLQATGGLKFYNVSLYDLQRLTQDAGNIEANFNNYINGYSKNVREIIDNFSIEKI  124
                 +L+ ++G  FYN SLY ++ L  D++NIE+NF  Y+NG+S N+++I++NF ++  
Sbjct  74   VMRERLLKNASGYSFYNTSLYTFETLLADPANIESNFRAYLNGFSENMQDILNNFKFDVE  133

Query  125  IAKLAKNELLFMLVDKFTEID--LHPDKVKNHEMGYIFEELLRRFSEMSNETAGEHYTPR  182
            I+ +A N++LF +++ F   D  L PDK+ + +MGY+FEEL+R+FSE  NE AG H+T+R
Sbjct  134  ITTMADNDVLFYVIQEFNKADAYLGPDKMTSTDMGYVFEELVRKFSESYNEEAGAHFTSR  193

Query  183  EVIRLMVNLLFAEQKEELKGKGIVRSVYDPACGTGGMLTITKEHIQKHINPKLEVILFGQ  242
            ++I LM +LL+ E+K+ L    + ++VYD + GT+ ML+   E+I+ ++N   EV  FGQ
Sbjct  194  DIIYLMTDLLLIEDKDTLFKEHVFKTVYDQTMGTSQMLSAMTERIH-DMNDTAEVATFGQ  252

Query  243  ELNEQTYAIAKSDVLMTGGEPDNIKLGTSFSNDQFRDKRFNFMLSNPPFGVSWKKEQSFI  302
            ELN +TYAI+K+D ++ GG+P+N+ LG+++++D+F +  F++ +SNPPFGV WKK+Q  +
Sbjct  253  ELNPETYAISKADTMIRGGDPENMALGSTLTSDRFEGFTFDYCISNPPFGVDWKKDQKAV  312

Query  303  NNEAE-DPGGRFHAGLPRVSDGAMLFLQHMISKMEPTGSRIAIIHNGSPLFTGDAGSGES  361
            + E E +  GRF  GLPRVSDG +LF  + ISK+  TG R+AIIHNGS+LF+G++G+GES
Sbjct  313  KAEHELGELGRFGVGLPRVSDGQLLFQLNGISKLKETG-RMAIIHNGSALFSGNPGAGES  371

Query  362  NIRKWIIESDWLEAIVALPTELFFNTGIATYIWIVTNRKPAHRRGKVQLVNAVSFAQKMR  421
             IR+ +IE+DWLE+I+ LP +LF+NTGI+TYIWI+T+ K+++R+GKVQLV+A +  +K R
Sbjct  372  LIRQYVIENDWLEGIIQLPNDLFYNTGISTYIWIITKDKSPERQGKVQLVDASNMYEKRR  431

Query  422  KSLGSKRNFitteqiqqitDIYTGFKDGEF--------CKVFDNEDFGFTKVTVERPEMK  473
            K++G KR  I+    + I + Y  F+D E+         K++ NE FGFT+VT+ERP+  
Sbjct  432  KNIGEKRVDISEACREMIVQAYGEFNDKEYYLGDGTVESKILKNESFGFTRVTIERPQRD  491

Query  474  KD-KIVKDKNGNPKPDTSLRDYEKIPLKVDIDEYFKREVLPHVPDAWMDRSKDKVGYEIN  532
             +  IV  KNG+   DT+LRD E IPL  DI+EYF RE+LP   DAWMDR KDK+GYEI 
Sbjct  492  ENGDIVYKKNGSKSVDTNLRDTEDIPLTEDINEYFEREILPFNQDAWMDRKKDKIGYEIP  551

Query  533  FTKYFYKYQPLRSLDEIKADILALE  557
            FT+ FYKY P  + + I   I  LE
Sbjct  552  FTRLFYKYTPPEPSEVISERIKQLE  576

17) Shel_19060 in NC_013165


> NC_002953_R1|4|G3|49484939|YP_042160.1|Staphylococcus_aureus_subsp._aureus_MSSA476|-|4742..6529|-|SAS0027|type 
I restriction 
enzyme methylase
Length=595

 Score =  435 bits (1639),  Expect = 4e-123, Method: Compositional matrix adjust.
 Identities = 260/585 (45%), Positives = 408/585 (70%), Gaps = 27/585 (4%)

Query  7    SSFIWGTADLLRSSFKQHEYGDIILPFTVMRRLDVVLEPTKQAVLEAA--AKKMPDALRD  64
            +++IW  AD+LR+ +K HEYG +ILP TV++RL+  L  T++ VL +A  ++ + D +R+
Sbjct  18   ANLIWNVADILRGLYKPHEYGKVILPMTVIKRLHDTLLKTRDKVLKTAENTQSINDVMRE  77

Query  65   TMLKKAAGVDFYNTSEFTMRGLLSDADGIRENLTKYVTSFSPEIADIFDKFKIFDV-IKd  123
             +LK+A+G  FYNTS +T   LL+D+  I  N+  Y+ +FS ++ DI+++FK FDV I  
Sbjct  78   RLLKNASGYSFYNTSLYTFETLLADPANIESNFRAYLNGFSENMQDILNNFK-FDVEITT  136

Query  124  lddndllflVVERFCNPRIDLSPASISNADMGDIYEELIRRFSEVSNETAGEHFSPRDGL  183
            + DND+LF V++ F ++   L+P  ++++DMG ++EEL+R+FSE  NE AG HF++RD +
Sbjct  137  MADNDVLFYVIQEFNKADAYLGPDKMTSTDMGYVFEELVRKFSESYNEEAGAHFTSRDII  196

Query  184  RLAAELLVVGEMDDLTQPNRIVKVCDPCAGTGGALTVFADRVAEINPQATVVTYAQEING  243
             L ++LL++ + D L + + +  V D   GT+  L+  ++R+ ++N  A V T++QE+N 
Sbjct  197  YLMTDLLLIEDKDTLFKEHVFKTVYDQTMGTSQMLSAMTERIHDMNDTAEVATFGQELNP  256

Query  244  QSYAICKSDTILKGGNIANVHLGDTLADDQMPGETFGYQISNPPYGVDWKKSQAAVRKEH  303
            ++YAI K+DT+++GG+  N+ LG TL+ D+  G TF+Y ISNPP+GVDWKK Q AV+ EH
Sbjct  257  ETYAISKADTMIRGGDPENMALGSTLTSDRFEGFTFDYCISNPPFGVDWKKDQKAVKAEH  316

Query  304  EQLGFAGRFGAGLPRISDGQLLFVQHMVAKMRPVDEGGGRIAVFLNGSPLFTGAAGSGES  363
            E LG  GRFG GLPR+SDGQLLF  + ++K++      GR+A++ NGS+LF+G +G+GES
Sbjct  317  E-LGELGRFGVGLPRVSDGQLLFQLNGISKLK----ETGRMAIIHNGSALFSGNPGAGES  371

Query  364  EVRRYLLQHDLVEAIVAMPNDFFFNTGIATYIWVLDNTKEPRRKGKVQLINANGIYTKMR  423
             +R+Y++++D +E+I+ +PND+F+NTGI+TYIW++ + K P R+GKVQL++A+ +Y K R
Sbjct  372  LIRQYVIENDWLEGIIQLPNDLFYNTGISTYIWIITKDKSPERQGKVQLVDASNMYEKRR  431

Query  424  KSLGSKRNEFTDEQIAQIVGLYNDFEDADPKL------SKVFANEEFGYVTVDVRRPQRD  477
            K++G KR ++++     IV  Y +F+D +  L      SK++ NE FG+  V + RPQRD
Sbjct  432  KNIGEKRVDISEACREMIVQAYGEFNDKEYYLGDGTVESKILKNESFGFTRVTIERPQRD  491

Query  478  ERGEIVRDKKGRPVADKELNDTENIPLTQDVDEYMAREVLPYAPDAWIEPRKQKKGQLLE  537
            E G+IV  K+G    D +L DTE+IPLT+D++EY  RE+LP+  DAW++ +K+K      
Sbjct  492  ENGDIVYKKNGSKSVDTNLRDTEDIPLTEDINEYFEREILPFNQDAWMDRKKDK------  545

Query  538  LKDGGTVGFEIPFTRHFYEYTPLRPSSEIFAEIRELEASIAEKLR  582
                  +G+EIPFTR FY YTP  PS  I   I++LE SI  +++
Sbjct  546  ------IGYEIPFTRLFYKYTPPEPSEVISERIKQLEESIIKNFQ  584

18) Dvul_0488 in NC_008751


> NC_002953_R1|4|G3|49484939|YP_042160.1|Staphylococcus_aureus_subsp._aureus_MSSA476|-|4742..6529|-|SAS0027|type 
I restriction 
enzyme methylase
Length=595

 Score =  428 bits (1613),  Expect = 4e-121, Method: Compositional matrix adjust.
 Identities = 274/584 (47%), Positives = 402/584 (69%), Gaps = 15/584 (2%)

Query  1    MNQQSLSAFIWSVADLLRGDYKQSEYGRVILPFTVLRRLDSVLESTKVAVLEELESRQKL  60
            +N Q  + +IW+VAD+LRG YK  EYG+VILP TV++RL+  L  T+  VL   E+ Q +
Sbjct  12   INVQKQANLIWNVADILRGLYKPHEYGKVILPMTVIKRLHDTLLKTRDKVLKTAENTQSI  71

Query  61   G-IAPDPFLLRVSGQSFFNTSPLDMKKLIGDQDHIGENLYSYLNGFSPEVRDIFERFEFH  119
              +  + +L   SG SF+NTS      L++D  +I  N+ +YLNGFS +++DI++ F F+
Sbjct  72   NDVMRERLLKNASGYSFYNTSLYTFETLLADPANIESNFRAYLNGFSENMQDILNNFKFD  131

Query  120  AQIDRLNKAGLLYQVAERFAQVN--LHPDEVDNHQMGLIFEELIRKFAELSNETAGEHFT  177
             +I  +   ++L+ V + F + +  L PD + + +MG +FEEL+RKF+E  NE AG HFT
Sbjct  132  VEITTMADNDVLFYVIQEFNKADAYLGPDKMTSTDMGYVFEELVRKFSESYNEEAGAHFT  191

Query  178  PREVIRLMVNLIFIEDDDILSKPGVVRTIYDPTAGTGGMLSIAGEYLDDHNPDARLTMSG  237
            +R++I LM +L++IED D L K  V +T+YD T GT+ MLS   E ++D N  A ++  G
Sbjct  192  SRDIIYLMTDLLLIEDKDTLFKEHVFKTVYDQTMGTSQMLSAMTERIHDMNDTAEVATFG  251

Query  238  QELNPESYAICKADMLIKGQDVSNITFGNTLSDDGHAGKHFDYMLSNPPFGvewkkveke  297
            QELNPE+YAI KAD +I+G D  N+++G+TL+ D   G  FDY +SNPPFGV+WKK +K 
Sbjct  252  QELNPETYAISKADTMIRGGDPENMALGSTLTSDRFEGFTFDYCISNPPFGVDWKKDQKA  311

Query  298  vrkeHEQQGFNGRFGPGLPRISDGSMLFLLHLISKMRPAAEGGSRFGIVLNGSPLFTGGA  357
            V+ EHE   + GRFG GLPR+SDG +LF L+ ISK++ ++    R +I+ NGS+LF+G +
Sbjct  312  VKAEHELGEL-GRFGVGLPRVSDGQLLFQLNGISKLKETG----RMAIIHNGSALFSGNP  366

Query  358  GSGESEIRRYVLENDLLEAIVGLPTDMFYNTGISTYVWIVSNRKAAHRKGKVQLIDASAM  417
            G+GES IR+YV+END LE+I+ LP D+FYNTGISTY+WI+++ K+++R+GKVQL+DAS M
Sbjct  367  GAGESLIRQYVIENDWLEGIIQLPNDLFYNTGISTYIWIITKDKSPERQGKVQLVDASNM  426

Query  418  WQKMRKSLGSKRKELSDDHISEIVRLYGEFAEAKL---DGKPVSRIFNSSDFGYRTITVE  474
             +K RK++G KR ++S+     IV+ YGEF +      DG   S+I+++  FG+  +T+E
Sbjct  427  YEKRRKNIGEKRVDISEACREMIVQAYGEFNDKEYYLGDGTVESKILKNESFGFTRVTIE  486

Query  475  RPTRDEAGNIMLGQRGKAKGKPVPDSKLRDTENVPLHEDVEAYFKREVLPHVPDAWIDHD  534
            RP RDE G+I+     K +G    D++LRDTE++PL ED++ YF RE+LP   DAW+D+ 
Sbjct  487  RPQRDENGDIVY----KKNGSKSVDTNLRDTEDIPLTEDINEYFEREILPFNQDAWMDRK  542

Query  535  KTKVGYEIPFNRHFYVFTPPRPLAEIDADLKQTTDRIKAMIEGL  578
            K K+GYEIPF R FY +TPP P   I   +KQ  + I   +++L
Sbjct  543  KDKIGYEIPFTRLFYKYTPPEPSEVISERIKQLEESIIKNFQAL  586

19) Nitsa_1299 in NC_014935


> NC_002953_R1|4|G3|49484939|YP_042160.1|Staphylococcus_aureus_subsp._aureus_MSSA476|-|4742..6529|-|SAS0027|type 
I restriction 
enzyme methylase
Length=595

 Score =  427 bits (1606),  Expect = 1e-120, Method: Compositional matrix adjust.
 Identities = 262/592 (45%), Positives = 402/592 (68%), Gaps = 47/592 (7%)

Query  5    KQKADLIWDIAGLLRGDYKRSDYGKVILPLTVLRRLDAVLAPTKEKVLAALPRVEKMSEN  64
            +++A+LIW++A++LRG YK  +YGKVILP+TV++RL+  L  T++KVL +    + +++ 
Sbjct  15   QKQANLIWNVADILRGLYKPHEYGKVILPMTVIKRLHDTLLKTRDKVLKTAENTQSINDV  74

Query  65   AKDLYLNKIAGYNFHNRSRFDFAKIVADPNNVAMNLRNYINGFSSNAREIIEYFNFDDQI  124
             ++  L++ +GY+F N S + F  ++ADP N+  N+R Y+NGFS N ++I++ F+FD +I
Sbjct  75   MRERLLKNASGYSFYNTSLYTFETLLADPANIESNFRAYLNGFSENMQDILNNFKFDVEI  134

Query  125  DRMDDPKSDLLYQVVKAFAE----MPFDDVDSMQMGYIFEELIRKFAEQSNETAGEHFTP  180
              M D  +D+L+ V++ F      +  D + S +MGY+FEEL+RKF+E  NE AG HFT+
Sbjct  135  TTMAD--NDVLFYVIQEFNKADAYLGPDKMTSTDMGYVFEELVRKFSESYNEEAGAHFTS  192

Query  181  REVIELMVNLLFNSDRE-IFKEGIVKTLYDPACGTGGMLSIGENHIKRLNPDAKLELFGQ  239
            R++I LM +LL+  D++ +FKE + KT+YD + GT+ MLS   ++I  +N  A +  FGQ
Sbjct  193  RDIIYLMTDLLLIEDKDTLFKEHVFKTVYDQTMGTSQMLSAMTERIHDMNDTAEVATFGQ  252

Query  240  EINPESYAICKSDTLIKGENPSNIKFGNTFTVDGLRDEKFDYMLSNPPFGVEWKKAAKTI  299
            E+NPE+YAI K+DT+I+G +P N+ +G+T+T D + +  FDY +SNPPFGV+WKK  K++
Sbjct  253  ELNPETYAISKADTMIRGGDPENMALGSTLTSDRFEGFTFDYCISNPPFGVDWKKDQKAV  312

Query  300  KAEYENLGFAGRFGAGLPRINDGSLLFLQHMISKMKPEGSRIGIVFNGSPLFTGQAGSGE  359
            KAE E LG  GRFG GLPR++DG LLF  + ISK+K E +R++I+ NGS+LF+G++G+GE
Sbjct  313  KAEHE-LGELGRFGVGLPRVSDGQLLFQLNGISKLK-ETGRMAIIHNGSALFSGNPGAGE  370

Query  360  SNIRRWIIENDWLEAIVALPDQLFYNTGIATYIWVLNNQKDAKCRGKIQLINATGSKDEA  419
            S IR+ +IENDWLE+I+ LP++LFYNTGI+TYIW++ ++K +  +GK+QL++A+      
Sbjct  371  SLIRQYVIENDWLEGIIQLPNDLFYNTGISTYIWIITKDKSPERQGKVQLVDASN-----  425

Query  420  LMEEGKRDFNRFWEKMPRSLGDKRKRIPTNDDERGINYITKLYGEFEEGEF--------V  471
                         EK  +++G+  KR+  ++  R +  I + YGEF++ E+         
Sbjct  426  -----------MYEKRRKNIGE--KRVDISEACREM--IVQAYGEFNDKEYYLGDGTVES  470

Query  472  KIFPNDYFGYWRVTVERPLRDEAGNIVTDTKGRPKPDKELRDTENIPFLREDEEGNLVPQ  531
            KI+ N+ FG+ RVT+ERP RDE G+IV   +G    D +LRDTE+IP          + +
Sbjct  471  KILKNESFGFTRVTIERPQRDENGDIVYKKNGSKSVDTNLRDTEDIP----------LTE  520

Query  532  SIEEYFEREVLPHVPDAWIDESKTKIGYEINFDKYFYEFKPLRSLDAIRADI  583
             I+EYFERE+LP   DAW+D  K KIGYEI F + FY + P  + + I   I
Sbjct  521  DINEYFEREILPFNQDAWMDRKKDKIGYEIPFTRLFYKYTPPEPSEVISERI  572

20) hsdM in NC_008702


> NC_002953_R1|4|G3|49484939|YP_042160.1|Staphylococcus_aureus_subsp._aureus_MSSA476|-|4742..6529|-|SAS0027|type 
I restriction 
enzyme methylase
Length=595

 Score =  426 bits (1603),  Expect = 2e-120, Method: Compositional matrix adjust.
 Identities = 267/615 (44%), Positives = 406/615 (67%), Gaps = 42/615 (6%)

Query  1    MNHQALSSFIWSVADLLRGDYKQSEYGKVILPFTVLRRLDCVLEATKPSVLAELE-AKTK  59
            +N Q  +++IW+VAD+LRG YK  EYGKVILP TV++RL+  L  T+  VL   E +++ 
Sbjct  12   INVQKQANLIWNVADILRGLYKPHEYGKVILPMTVIKRLHDTLLKTRDKVLKTAENTQSI  71

Query  60   AGLNPDPFLLRKSGQSFYNTAPLDLVKLLGDQDHIRQNLYTYVQAFSPAARDIFERFDFF  119
             ++  + +L   SG SFYNT+   +  LL+D  +I  N+ +Y+++FS   +DI++ F F 
Sbjct  72   NDVMRERLLKNASGYSFYNTSLYTFETLLADPANIESNFRAYLNGFSENMQDILNNFKFD  131

Query  120  TQVERLAKANLLYLVTEKFANID--LHPEAVDNTSMGLVFEELIRKFAEISNETAGEHFT  177
             ++  +A  ++L+ V + F + D  L P+ + +T MG VFEEL+RKF+E  NE AG HFT
Sbjct  132  VEITTMADNDVLFYVIQEFNKADAYLGPDKMTSTDMGYVFEELVRKFSESYNEEAGAHFT  191

Query  178  PREVIRLMVNLLFIEDDDVLTPGNAVVRTIYDPTAGTGGMLSVAGEFLLEHNPQARLTMF  237
            +R++I LM +LL+IED D L   + V +T+YD T GT+ MLS   E + + N  A ++ F
Sbjct  192  SRDIIYLMTDLLLIEDKDTLFKEH-VFKTVYDQTMGTSQMLSAMTERIHDMNDTAEVATF  250

Query  238  GQELNDESYAICKADMLIKGQDVANIVAGNTLSDDGHGARKFDYMLSNPPFGVEWKKVEK  297
            GQELN E+YAI KAD +I+G D  N+  G+TL+ D   +  FDY +SNPPFGV+WKK +K
Sbjct  251  GQELNPETYAISKADTMIRGGDPENMALGSTLTSDRFEGFTFDYCISNPPFGVDWKKDQK  310

Query  298  AVRQEHEQKGFDGRFGPGLPRVSDGSMLFLMHLLSKMRPAQDGGSRFGIVLNGSPLFTGG  357
            AV+ EHE   + GRFG GLPRVSDG +LF ++ +SK++ +    +R +I+ NGS+LF+G 
Sbjct  311  AVKAEHELGEL-GRFGVGLPRVSDGQLLFQLNGISKLKET----GRMAIIHNGSALFSGN  365

Query  358  AGSGESEIRRYVLENDLVEAIVGLPTDMFYNTGIATYVWIISNRKKADRKGQVQLIDASS  417
            +G+GES IR+YV+END +E+I+ LP D+FYNTGI+TY+WII++ K ++R+G+VQL+DAS+
Sbjct  366  PGAGESLIRQYVIENDWLEGIIQLPNDLFYNTGISTYIWIITKDKSPERQGKVQLVDASN  425

Query  418  FWQKMRKSLGSKRKEMSDAHIATVTRLFGSFTEAEYITVFDAAGQQLGEPQLVTNTDTPP  477
              +K RK++G KR ++S+A    + + +G F + EY          LG+  + +      
Sbjct  426  MYEKRRKNIGEKRVDISEACREMIVQAYGEFNDKEYY---------LGDGTVES------  470

Query  478  KAPEGGRLKRVPIARIFRNQDFGYTTITVERPLKDEAGKPVLGSKGARRGKPQADSALRD  537
                          +I++N+ FG+T +T+ERP +DE G  V   +G++      D+ LRD
Sbjct  471  --------------KILKNESFGFTRVTIERPQRDENGDIVYKKNGSKS----VDTNLRD  512

Query  538  TENVPLGEDISAYFKREVLPHAPDAWIDETKSKVGYEIPFNRHFYVFEPPRSLHAIDEEL  597
            TE++PL EDI+ YF RE+LP   DAW+D  K K+GYEIPF R FY + PP + + I E +
Sbjct  513  TEDIPLTEDINEYFEREILPFNQDAWMDRKKDKIGYEIPFTRLFYKYTPPEPSEVISERI  572

Query  598  KTVSANIMKMLEGLA  612
            K +  +I+K +++L+
Sbjct  573  KQLEESIIKNFQALS  587

21) RALTA_A0832 in NC_010528


> NC_002953_R1|4|G3|49484939|YP_042160.1|Staphylococcus_aureus_subsp._aureus_MSSA476|-|4742..6529|-|SAS0027|type 
I restriction 
enzyme methylase
Length=595

 Score =  426 bits (1604),  Expect = 2e-120, Method: Compositional matrix adjust.
 Identities = 263/614 (43%), Positives = 413/614 (68%), Gaps = 41/614 (6%)

Query  1    MNHQALSSFIWSVADLLRGNYKQSEYGRVILPFTVLRRLDCVLAITKPAVLAEFE-AKTQ  59
            +N Q  +++IW+VAD+LRG YK  EYG+VILP TV++RL+  L  T+  VL   E +++ 
Sbjct  12   INVQKQANLIWNVADILRGLYKPHEYGKVILPMTVIKRLHDTLLKTRDKVLKTAENTQSI  71

Query  60   AGINPDPFLQRKAKQSFYNVSPLDLVKLLGDQDHIRQNLYSYLQGFSASARDIFERFDFH  119
             ++  + +L+  +  SFYN S   +  LL+D  +I  N+ +YL+GFS + +DI++ F F+
Sbjct  72   NDVMRERLLKNASGYSFYNTSLYTFETLLADPANIESNFRAYLNGFSENMQDILNNFKFD  131

Query  120  MQVERLAKANLLYLVTEKFANID--LHPDTVDNAQMGLVFEELIRKFAEISNETAGEHFT  177
            +++  +A  ++L+ V + F + D  L PD + +++MG VFEEL+RKF+E  NE AG HFT
Sbjct  132  VEITTMADNDVLFYVIQEFNKADAYLGPDKMTSTDMGYVFEELVRKFSESYNEEAGAHFT  191

Query  178  PREVIRLMVNLIFIEDSDVLTAGNAVVRTIYDPTAGTGGMLSVADEFLREHNPSARLTMY  237
            +R++I LM +L++IED D L   + V +T+YD T GT+ MLS   E +++ N +A ++ +
Sbjct  192  SRDIIYLMTDLLLIEDKDTLFKEH-VFKTVYDQTMGTSQMLSAMTERIHDMNDTAEVATF  250

Query  238  GQELNDESYAICKADMLIKGQDVGNIVAGNTLSDDGHGARKFDYMLSNPPFGVEWKKVEK  297
            GQELN E+YAI KAD +I+G D  N+  G+TL+ D   +  FDY +SNPPFGV+WKK +K
Sbjct  251  GQELNPETYAISKADTMIRGGDPENMALGSTLTSDRFEGFTFDYCISNPPFGVDWKKDQK  310

Query  298  AVRQEHEQRGFDGRFGPGLPRVSDGSMLFLMHLLSKMRPAADGGSRFGIVLNGSPLFTGG  357
            AV+ EHE   + GRFG GLPRVSDG +LF ++ +SK++ ++    R +I+ NGS+LF+G 
Sbjct  311  AVKAEHELGEL-GRFGVGLPRVSDGQLLFQLNGISKLKETG----RMAIIHNGSALFSGN  365

Query  358  AGSGESEIRRYVLENDLVEAIVGLPTDMFYNTGIATYVWILSNKKPEDRKGWVQLIDASS  417
            +G+GES IR+YV+END +E+I+ LP D+FYNTGI+TY+WI+++ K+ +R+G VQL+DAS+
Sbjct  366  PGAGESLIRQYVIENDWLEGIIQLPNDLFYNTGISTYIWIITKDKSPERQGKVQLVDASN  425

Query  418  FWQKMRKSLGSKRKEMNDEQIAMVTRLFGDFVEAETATVLDADGKEVGRYVVAATAQPPE  477
              +K RK++G KR ++++    M+ + +G+F + E              Y+  +T +   
Sbjct  426  MYEKRRKNIGEKRVDISEACREMIVQAYGEFNDKEY-------------YLGDGTVE---  469

Query  478  APVGGRVKLAPISRIFRNEEFGYTTITVERPLRDENGQLMLGVKGKQKGKPQADSSLRDT  537
                        S+I++NE FG+T +T+ERP RDENG+++     K++G    D++LRDT
Sbjct  470  ------------SKILKNESFGFTRVTIERPQRDENGDIVY----KKNGSKSVDTNLRDT  513

Query  538  ENVPLDEEIDAYFVREVLPHAPDAWVDDDKSKVGYEIPFNRHFYVFEPPRDLHTIDEELK  597
            E++PL E+I+ YF RE+LP   DAW+D  K K+GYEIPF R FY + PP   + I E +K
Sbjct  514  EDIPLTEDINEYFEREILPFNQDAWMDRKKDKIGYEIPFTRLFYKYTPPEPSEVISERIK  573

Query  598  AVSVNIMRMLEELA  611
             +  +I++ ++ L+
Sbjct  574  QLEESIIKNFQALS  587

22) hsdM in NC_016790


> NC_002953_R1|4|G3|49484939|YP_042160.1|Staphylococcus_aureus_subsp._aureus_MSSA476|-|4742..6529|-|SAS0027|type 
I restriction 
enzyme methylase
Length=595

 Score =  421 bits (1586),  Expect = 5e-119, Method: Compositional matrix adjust.
 Identities = 260/600 (44%), Positives = 404/600 (68%), Gaps = 42/600 (7%)

Query  5    GSFIWGTADILRGPYKASQYGNVILPMTILRRLDCVLEEHRTTIEPLVERFGSNPELLSA  64
            +++IW  ADILRG YK+ +YG+VILPMT+++RL+  L   R  +    E   S  +++  
Sbjct  18   ANLIWNVADILRGLYKPHEYGKVILPMTVIKRLHDTLLKTRDKVLKTAENTQSINDVMRE  77

Query  65   QVQR-ATGLPFYNTSPWTLKTLLGDPKGIEANLKHYVNGFSDNM-DVFERFKLAEEIATM  122
            ++ + A+G +FYNTS  T+ TLL+DP  IE+N++ Y+NGFS+NM D+++ FK+  EI+TM
Sbjct  78   RLLKNASGYSFYNTSLYTFETLLADPANIESNFRAYLNGFSENMQDILNNFKFDVEITTM  137

Query  123  AEKNILYIVVERFSNID--LHPKTVTNAEMGDLYEYLIRTFNESSNEAPGEHFTPRDAIR  180
            A++++L+ V++ F++ D  L P  +T+++MG ++E L+R F+ES NE +G HFT+RD I 
Sbjct  138  ADNDVLFYVIQEFNKADAYLGPDKMTSTDMGYVFEELVRKFSESYNEEAGAHFTSRDIIY  197

Query  181  LLVDLVFAGDDEALSTPGAIRSIYDPTVGTGGMLSIAEEHLIGTSDRPGLNPQAQLRLYG  240
            L+ DL++  D ++L     ++++YD T+GT+ MLS   E++       ++N  A++  +G
Sbjct  198  LMTDLLLIEDKDTLFKEHVFKTVYDQTMGTSQMLSAMTERI------HDMNDTAEVATFG  251

Query  241  QEWNDHSYAVCKSDLLIKGYDSSNIQLGDTLADDKFAGQTFDYCMSNPPYGDDWKASQSA  300
            QE N ++YA+ K+D +I+G D+ N+ LG TL+ D+F G TFDYC+SNPP+G DWK  Q A
Sbjct  252  QELNPETYAISKADTMIRGGDPENMALGSTLTSDRFEGFTFDYCISNPPFGVDWKKDQKA  311

Query  301  VMEDLKELGSSSRFYAGGDKPKQNVPAVSDGQMLFLQHVVSKLRPKVKGGGRGGIVMNGS  360
            V  +  ELG  +RF  G       +P VSDGQ+LF  + +SKL    K  GR +I+ NGS
Sbjct  312  VKAE-HELGELGRFGVG-------LPRVSDGQLLFQLNGISKL----KETGRMAIIHNGS  359

Query  361  PLFNGAAESGPSNIRKWMLEHDLVDAIVALPTDMFYNTGIATYIWIVDNNKPEERQGKVQ  420
            +LF+G + +G S IR+ ++E+D +++I+ LP D+FYNTGI+TYIWI+ ++K+ ERQGKVQ
Sbjct  360  ALFSGNPGAGESLIRQYVIENDWLEGIIQLPNDLFYNTGISTYIWIITKDKSPERQGKVQ  419

Query  421  LIDGTEFYEKMRKKLGDKGREIREDNRATIVQLYDDYVDTE--------HCKIVPIEEFA  472
            L+D+++ YEK RK++G+K  +I E  R  IVQ Y+++ D E        + KI+  E F+
Sbjct  420  LVDASNMYEKRRKNIGEKRVDISEACREMIVQAYGEFNDKEYYLGDGTVESKILKNESFG  479

Query  473  YWLVTVERPRRDEHGEVITNARGKKQPDTALRDTERVPFTYDGNTQGDGGRQETIRAYFD  532
            +  VT+ERP+RDE+G+++ +  G K  DT LRDTE +P+T            E I  YF+
Sbjct  480  FTRVTIERPQRDENGDIVYKKNGSKSVDTNLRDTEDIPLT------------EDINEYFE  527

Query  533  AEVKPYVPDAWVDEKKTKIGYEIPFTRFFYRYQPPRPLEEIDAELHQVTTEILQLLNEVT  592
             E+ P+  DAW+D KK KIGYEIPFTR+FY+Y PP P E I   + Q+   I++ ++ ++
Sbjct  528  REILPFNQDAWMDRKKDKIGYEIPFTRLFYKYTPPEPSEVISERIKQLEESIIKNFQALS  587

23) C770_GR4Chr0590 in NC_019845


> NC_002953_R1|4|G3|49484939|YP_042160.1|Staphylococcus_aureus_subsp._aureus_MSSA476|-|4742..6529|-|SAS0027|type 
I restriction 
enzyme methylase
Length=595

 Score =  419 bits (1579),  Expect = 2e-118, Method: Compositional matrix adjust.
 Identities = 268/614 (44%), Positives = 407/614 (67%), Gaps = 40/614 (6%)

Query  1    MNQQALSAFIWSVADLLRGDYKQADYGKVILPFTVLRRIDCVLELTKEAVL-AEHVAKTA  59
            +N Q  + +IW+VAD+LRG YK  +YGKVILP TV++R++  L  T++ VL + + +++ 
Sbjct  12   INVQKQANLIWNVADILRGLYKPHEYGKVILPMTVIKRLHDTLLKTRDKVLKTAENTQSI  71

Query  60   AGINPEPFVLRKAGQTFYNVSKLDMRLLMGDQDNIAANLYAYIQGFSADVRDIFERFEFA  119
             ++  E ++   +G +FYN S      L++D  NI +N+ AY++GFS +++DI++ F F 
Sbjct  72   NDVMRERLLKNASGYSFYNTSLYTFETLLADPANIESNFRAYLNGFSENMQDILNNFKFD  131

Query  120  VQIDRLAKAKLLYQVTEKFARID--LHPDKVSNHQMGLVFEELIRKFSELSNETAGEHFT  177
            V+I  +A   +L+ V + F + D  L PDK+++ +MG VFEEL+RKFSE  NE AG HFT
Sbjct  132  VEITTMADNDVLFYVIQEFNKADAYLGPDKMTSTDMGYVFEELVRKFSESYNEEAGAHFT  191

Query  178  PREVIRLMVNLLFVEDDDILSKPGVVRTIYDPTAGTGGMLSIAEEYLSEHNEQARLVMNG  237
            +R++I LM +LL++ED D L K  V +T+YD T GT+ MLS   E + + N+ A +   G
Sbjct  192  SRDIIYLMTDLLLIEDKDTLFKEHVFKTVYDQTMGTSQMLSAMTERIHDMNDTAEVATFG  251

Query  238  QELNPESYAICKADMLIKGQDVSNIVFGNTLSDDGHAGEKFDYMLSNPPFGVEWKKVEKE  297
            QELNPE+YAI KAD +I+G D  N+ +G+TL+ D   G  FDY +SNPPFGV+WKK +K 
Sbjct  252  QELNPETYAISKADTMIRGGDPENMALGSTLTSDRFEGFTFDYCISNPPFGVDWKKDQKA  311

Query  298  IRAEHEQKGFNGRFGPGLPRVSDGSLLFLMHLISKMRPAVDGGSRFAIVLNGSPLFTGGA  357
            ++AEHE   + GRFG GLPRVSDG LLF ++ ISK++ +    +R AI+ NGS+LF+G +
Sbjct  312  VKAEHELGEL-GRFGVGLPRVSDGQLLFQLNGISKLKET----GRMAIIHNGSALFSGNP  366

Query  358  GSGESEIRRYVLENDLLEAIIALPTDMFYNTGISTYVWVLSNRKPDHRKGKVQLIDASSF  417
            G+GES IR+YV+END LE+II LP D+FYNTGISTY+W++++ K+ +R+GKVQL+DAS+ 
Sbjct  367  GAGESLIRQYVIENDWLEGIIQLPNDLFYNTGISTYIWIITKDKSPERQGKVQLVDASNM  426

Query  418  WQKMRKSLGSKRKEMGDPDIASVTRLFGSFSEAQIATVLDAGGKEIGREIVVDGEKLPAA  477
             +K RK++G KR +++++    + + +G F++ +    L+ G  E               
Sbjct  427  YEKRRKNIGEKRVDISEACREMIVQAYGEFNDKEY--YLGDGTVE---------------  469

Query  478  PEGGKVKLEPLSRIFPSEAFGYRTITVERPLRDEkgaavvgtkgkakgkPQADSSLRDSE  537
                       S+I+ +E+FG+  +T+ERP RDE+G  V   +G        D++LRD+E
Sbjct  470  -----------SKILKNESFGFTRVTIERPQRDENGDIVYKKNGS----KSVDTNLRDTE  514

Query  538  NVPLGEEVESYFAREVLPHAPDAWIDHEKTRTGYEIPFNRHFYVFEPPRPLAEIDADLKQ  597
            ++PL E+++ YF RE+LP   DAW+D+ K + GYEIPF R FY + PP P   I   +KQ
Sbjct  515  DIPLTEDINEYFEREILPFNQDAWMDRKKDKIGYEIPFTRLFYKYTPPEPSEVISERIKQ  574

Query  598  VTGRILQMIGELSA  611
            +   I++ +  LS+
Sbjct  575  LEESIIKNFQALSG  588

24) hsdM in NC_016802


> NC_002953_R1|4|G3|49484939|YP_042160.1|Staphylococcus_aureus_subsp._aureus_MSSA476|-|4742..6529|-|SAS0027|type 
I restriction 
enzyme methylase
Length=595

 Score =  419 bits (1576),  Expect = 3e-118, Method: Compositional matrix adjust.
 Identities = 255/600 (43%), Positives = 406/600 (68%), Gaps = 42/600 (7%)

Query  5    GSFIWGTADVLRGPYKASQYGNVILPMTILRRLDCVLEEHRTTIEPLVERFGNNPELLSA  64
            +++IW  AD+LRG YK+ +YG+VILPMT+++RL+  L   R  +    E   +  +++  
Sbjct  18   ANLIWNVADILRGLYKPHEYGKVILPMTVIKRLHDTLLKTRDKVLKTAENTQSINDVMRE  77

Query  65   QVQR-ATGLPFYNTSPWSLKTLLGDPKGIEANLKHYVNGFSDNM-DVFERFKLADEIATM  122
            ++ + A+G +FYNTS  ++ TLL+DP  IE+N++ Y+NGFS+NM D+++ FK+  EI+TM
Sbjct  78   RLLKNASGYSFYNTSLYTFETLLADPANIESNFRAYLNGFSENMQDILNNFKFDVEITTM  137

Query  123  AEKNILYIVVERFSNID--LHPKTVTNAEMGDLYEYLIRTFNESSNEAPGEHFTPRDAIR  180
            A++++L+ V++ F++ D  L P  +T+++MG ++E L+R F+ES NE +G HFT+RD I 
Sbjct  138  ADNDVLFYVIQEFNKADAYLGPDKMTSTDMGYVFEELVRKFSESYNEEAGAHFTSRDIIY  197

Query  181  LLVDLVFAGDDEALSTPGAIRSIYDPTVGTGGMLSIAEEHLIGTSDRPGLNPQAQLRLYG  240
            L+ DL++  D ++L     ++++YD T+GT+ MLS   E++       ++N  A++  +G
Sbjct  198  LMTDLLLIEDKDTLFKEHVFKTVYDQTMGTSQMLSAMTERI------HDMNDTAEVATFG  251

Query  241  QEWNDHSYAVCKSDLLIKGYDSSNIQLGDTLADDKFAGQTFDYCMSNPPYGDDWKASQSA  300
            QE N ++YA+ K+D +I+G D+ N+ LG TL+ D+F G TFDYC+SNPP+G DWK  Q A
Sbjct  252  QELNPETYAISKADTMIRGGDPENMALGSTLTSDRFEGFTFDYCISNPPFGVDWKKDQKA  311

Query  301  VMEDLKELGSSSRFYAGGDKPKQNVPAVSDGQMLFLQHVVSKLRPKVKGGGRGGIVMNGS  360
            V  +  ELG  +RF  G       +P VSDGQ+LF  + +SKL    K  GR +I+ NGS
Sbjct  312  VKAE-HELGELGRFGVG-------LPRVSDGQLLFQLNGISKL----KETGRMAIIHNGS  359

Query  361  PLFNGAAESGPSNIRKWLLEHDLVDAIVALPNDMFYNTGIATYIWIVDNNKPEERQGKVQ  420
            +LF+G + +G S IR+ ++E+D +++I+ LPND+FYNTGI+TYIWI+ ++K+ ERQGKVQ
Sbjct  360  ALFSGNPGAGESLIRQYVIENDWLEGIIQLPNDLFYNTGISTYIWIITKDKSPERQGKVQ  419

Query  421  LIDGTEFYQKMRKKLGDKGREISEANRATIVKLYDDYVETE--------HCRIVPIEEFA  472
            L+D+++ Y+K RK++G+K  +ISEA R  IV+ Y+++ + E        + +I+  E F+
Sbjct  420  LVDASNMYEKRRKNIGEKRVDISEACREMIVQAYGEFNDKEYYLGDGTVESKILKNESFG  479

Query  473  YWLVTVERPRRDEHGEVITNARGKKQPDVALRDTERVPFTYGGNAQGDGGRQETIRAYFD  532
            +  VT+ERP+RDE+G+++ +  G K  D  LRDTE +P+T            E I  YF+
Sbjct  480  FTRVTIERPQRDENGDIVYKKNGSKSVDTNLRDTEDIPLT------------EDINEYFE  527

Query  533  AEVKPYVPDAWVDEKKTKIGYEIPFTRFFYRYQPPRPLEEIDAELHQVTTVILQLLNEVT  592
             E+ P+  DAW+D KK KIGYEIPFTR+FY+Y PP P E I   + Q+   I++ ++ ++
Sbjct  528  REILPFNQDAWMDRKKDKIGYEIPFTRLFYKYTPPEPSEVISERIKQLEESIIKNFQALS  587

25) Rsph17029_1857 in NC_009049


> NC_002953_R1|4|G3|49484939|YP_042160.1|Staphylococcus_aureus_subsp._aureus_MSSA476|-|4742..6529|-|SAS0027|type 
I restriction 
enzyme methylase
Length=595

 Score =  419 bits (1576),  Expect = 4e-118, Method: Compositional matrix adjust.
 Identities = 272/614 (45%), Positives = 408/614 (67%), Gaps = 40/614 (6%)

Query  1    MNQQDLSAFLWSVADLLRGDYKQSDYGKVILPFTVLRRIDCVLAPTKEAVL-AEYKIRKE  59
            +N Q  + ++W+VAD+LRG YK  +YGKVILP TV++R++  L  T++ VL +  + +  
Sbjct  12   INVQKQANLIWNVADILRGLYKPHEYGKVILPMTVIKRLHDTLLKTRDKVLKTAENTQSI  71

Query  60   QGMPPAPFLRKASGQTFYNASRFDLGKLMGDQDNIALNLRAYIQGFSPEVRDIFDHFEFD  119
            +++    +L++ASG +FYN+S + +  L++D  NI  N+RAY++GFS +++DI+++F FD
Sbjct  72   NDVMRERLLKNASGYSFYNTSLYTFETLLADPANIESNFRAYLNGFSENMQDILNNFKFD  131

Query  120  TQIDRLAKAGLLYLVTEKFAKAP--LHPDRVTNHQMGLVFEELIRRFAELSNETAGEHFT  177
             +I  +A  ++L+ V + F KA   L PD++T+ +MG VFEEL+R+F+E  NE AG HFT
Sbjct  132  VEITTMADNDVLFYVIQEFNKADAYLGPDKMTSTDMGYVFEELVRKFSESYNEEAGAHFT  191

Query  178  PREVIRLMVNLIFVEDDAVLSKPGVVRTIYDPTAGTGGMLSVAEEYLTDMNPAASVALSG  237
            +R++I LM +L+++ED   L K  V +T+YD T GT+ MLS   E + DMN +A VA  G
Sbjct  192  SRDIIYLMTDLLLIEDKDTLFKEHVFKTVYDQTMGTSQMLSAMTERIHDMNDTAEVATFG  251

Query  238  QELNPESYAICKADMLIKGQDVGNIAFGNTLSDDFHPGETFDYMLSNPPFGVEWKKVEKV  297
            QELNPE+YAI KAD +I+G D  N+A+G+TL+ D   G TFDY +SNPPFGV+WKK +K 
Sbjct  252  QELNPETYAISKADTMIRGGDPENMALGSTLTSDRFEGFTFDYCISNPPFGVDWKKDQKA  311

Query  298  VRAEHEQKGHAGRFGPGLPRVSDGSLLFLMHLLSKMRPAAQGGCRFGIVLNGSPLFTGGA  357
            V+AEHE  G+ GRFG GLPRVSDG LLF ++ +SK++ ++    R +I+ NGS+LF+G +
Sbjct  312  VKAEHEL-GELGRFGVGLPRVSDGQLLFQLNGISKLKETG----RMAIIHNGSALFSGNP  366

Query  358  GSGESEIRRHVLESDLVEAIVALPTDMFYNTGIATYVWILTNRKAEARKGKVQLIDGSSF  417
            G+GES IR+ V+E+D +E+I+ LP D+FYNTGI+TY+WI+T+ K+  R+GKVQL+D+S+ 
Sbjct  367  GAGESLIRQYVIENDWLEGIIQLPNDLFYNTGISTYIWIITKDKSPERQGKVQLVDASNM  426

Query  418  WQKMRKSLGSKRKQMGDADIATITRLFGGFIEADLARVFDAAGKevgtvvvtpgeapptp  477
             +K RK++G KR ++++A    I + +G F + +    + + G                 
Sbjct  427  YEKRRKNIGEKRVDISEACREMIVQAYGEFNDKEY---YLGDGTVE--------------  469

Query  478  peggRVKLAPLSRIRPNESFGYRTITVERPLRDEQGRvvlgqkgklkgkpqpDPALRDTE  537
                       S+I  NESFG+  +T+ERP RDE+G    +   K +G    D  LRDTE
Sbjct  470  -----------SKILKNESFGFTRVTIERPQRDENG----DIVYKKNGSKSVDTNLRDTE  514

Query  538  NVPLTEDVAAYFAREVLPHAPDACIDPEKTKVGYEIPFNRHFYVFEPPRPLAQIDADLAE  597
            ++PLTED+  YF RE+LP   DA +D  K K+GYEIPF R FY + PP P   I   + +
Sbjct  515  DIPLTEDINEYFEREILPFNQDAWMDRKKDKIGYEIPFTRLFYKYTPPEPSEVISERIKQ  574

Query  598  VTTRIQAMLAGLSA  611
            +   I   + +LS+
Sbjct  575  LEESIIKNFQALSG  588

26) Rta_21410 in NC_015677


> NC_002953_R1|4|G3|49484939|YP_042160.1|Staphylococcus_aureus_subsp._aureus_MSSA476|-|4742..6529|-|SAS0027|type 
I restriction 
enzyme methylase
Length=595

 Score =  418 bits (1573),  Expect = 6e-118, Method: Compositional matrix adjust.
 Identities = 270/593 (46%), Positives = 408/593 (69%), Gaps = 16/593 (2%)

Query  18   RFPASHMNQQTLSAFLWSVADLLRGDYRQSDYGKVILPFTVLRRL-DCVLASTkaavlae  76
            R   + +N Q  + ++W+VAD+LRG Y+  +YGKVILP TV++RL D +L +    + + 
Sbjct  6    RHQQTSINVQKQANLIWNVADILRGLYKPHEYGKVILPMTVIKRLHDTLLKTRDKVLKTA  65

Query  77   kkalaakklPPEQFLLRKSGQSFYNDSDLDMKTLLGDADHIAQNLYRYIQGFSPAVRDVF  136
             ++ + + +  E++L   SG SFYN S     TLL+D+ +I  N+  Y++GFS  ++D++
Sbjct  66   ENTQSINDVMRERLLKNASGYSFYNTSLYTFETLLADPANIESNFRAYLNGFSENMQDIL  125

Query  137  ERFEFQAQIDRLAKARLLYHVAEKFANVD--LHPDKVSNTQMGHVFEELIRKFAELSNET  194
            + F F+ +I  +A   +L+ V + F + D  L PDK+++T+MG VFEEL+RKF+E  NE 
Sbjct  126  NNFKFDVEITTMADNDVLFYVIQEFNKADAYLGPDKMTSTDMGYVFEELVRKFSESYNEE  185

Query  195  AGEHFTPREVIRLMVNLIFIEDDAALSQPHAVRTLYDPTAGTGGMLSVAGEYLAEHSPTA  254
            AG HFT+R++I LM +L++IED  +L + H  +T+YD T GT+ MLS   E + + + TA
Sbjct  186  AGAHFTSRDIIYLMTDLLLIEDKDTLFKEHVFKTVYDQTMGTSQMLSAMTERIHDMNDTA  245

Query  255  RLTVHGQELNPESYAICKADMLIKGQDVSNIVFGNTLSDDGHAHKRFDYMLSNPPFGvew  314
             ++  GQELNPE+YAI KAD +I+G D  N+ +G+TL+ D      FDY +SNPPFGV+W
Sbjct  246  EVATFGQELNPETYAISKADTMIRGGDPENMALGSTLTSDRFEGFTFDYCISNPPFGVDW  305

Query  315  kkvekevrkeHEQQGYNGRFGPGLPRVSDGSMLFLLHLLSKMRPAAEGGSRFGIVLNGSP  374
            KK +K V+ EHE     GRFG GLPRVSDG +LF L+ +SK++ ++    R +I+ NGS+
Sbjct  306  KKDQKAVKAEHELGEL-GRFGVGLPRVSDGQLLFQLNGISKLKETG----RMAIIHNGSA  360

Query  375  LFTGGAGSGESEIRRYVLENDLLEAIVGLPTDMFYNTGISTYVWIVGNRKPAQRRGKVQL  434
            LF+G +G+GES IR+YV+END LE+I+ LP D+FYNTGISTY+WI+ + K+++R+GKVQL
Sbjct  361  LFSGNPGAGESLIRQYVIENDWLEGIIQLPNDLFYNTGISTYIWIITKDKSPERQGKVQL  420

Query  435  IDASGMWQKMRKSLGSKRRELSDAHIDRITRLFGNFEEARD---ESGKPISRIFKNEDFG  491
            +DAS M +K RK++G KR ++S+A  + I + +G+F++ ++     G   S+I+KNE FG
Sbjct  421  VDASNMYEKRRKNIGEKRVDISEACREMIVQAYGEFND-KEYYLGDGTVESKILKNESFG  479

Query  492  YRTITVERPLKDEQGRRVLGERGKLKGKPQPDAALRDTENVPLTEDVEAYFQREVLPHAP  551
            +  +T+ERP +DE+G  V     K +G    D+ LRDTE++PLTED++ YF+RE+LP   
Sbjct  480  FTRVTIERPQRDENGDIVY----KKNGSKSVDTNLRDTEDIPLTEDINEYFEREILPFNQ  535

Query  552  DAWIDEDKTKVGYEIPFNRHFYVFKPPRPLAEIDAELKQTTDRILEMIKGLSA  604
            DAW+D  K K+GYEIPF R FY + PP P   I   +KQ  + I+  +++LS+
Sbjct  536  DAWMDRKKDKIGYEIPFTRLFYKYTPPEPSEVISERIKQLEESIIKNFQALSG  588

27) hsdM-1 in NC_012559


> NC_002953_R1|4|G3|49484939|YP_042160.1|Staphylococcus_aureus_subsp._aureus_MSSA476|-|4742..6529|-|SAS0027|type 
I restriction 
enzyme methylase
Length=595

 Score =  416 bits (1566),  Expect = 2e-117, Method: Compositional matrix adjust.
 Identities = 267/609 (44%), Positives = 397/609 (66%), Gaps = 42/609 (6%)

Query  7    SAFIWSVADLLRGDYKQSEYGKVILPFTVLRRLDCVLADTKPAVLAELQ-LRSDAGVNPE  65
            + +IW+VAD+LRG YK  EYGKVILP TV++RL+  L  T+  VL   +  +S  +V  E
Sbjct  18   ANLIWNVADILRGLYKPHEYGKVILPMTVIKRLHDTLLKTRDKVLKTAENTQSINDVMRE  77

Query  66   PFLLRKAGQSFYNTSPLDLSKLLGDQDHIRENLYAYIQGFSPAARDIFERFDFFTQVERL  125
             +L   +G SFYNTS   +  LL+D  +I  N+ AY++GFS   +DI++ F F  ++  +
Sbjct  78   RLLKNASGYSFYNTSLYTFETLLADPANIESNFRAYLNGFSENMQDILNNFKFDVEITTM  137

Query  126  AKAGLLYLVTEKFANID--LHPASVDNASMGLVFEELIRKFAEISNETAGEHFTPREVIR  183
            A  ++L+ V + F + D  L P  + ++ MG VFEEL+RKF+E  NE AG HFT+R++I 
Sbjct  138  ADNDVLFYVIQEFNKADAYLGPDKMTSTDMGYVFEELVRKFSESYNEEAGAHFTSRDIIY  197

Query  184  LMVNLLFIEDDDVLTAGNAVVRTLYDPTAGTGGMLSVAGEFLAEHNPQARLTLFGQELND  243
            LM +LL+IED D L   + V +T+YD T GT+ MLS   E + + N  A ++ FGQELN 
Sbjct  198  LMTDLLLIEDKDTLFKEH-VFKTVYDQTMGTSQMLSAMTERIHDMNDTAEVATFGQELNP  256

Query  244  ESYAICKADMLIKGQDVGNIVAGNTLSDDGHGARKFDYMLSNPPFGVEWKKVEKAVRDEH  303
            E+YAI KAD +I+G D  N+  G+TL+ D   +  FDY +SNPPFGV+WKK +KAV+ EH
Sbjct  257  ETYAISKADTMIRGGDPENMALGSTLTSDRFEGFTFDYCISNPPFGVDWKKDQKAVKAEH  316

Query  304  ERKGFDGRFGPGLPRVSDGSMLFLMHLLSKMRPASEGGCRFGIVLNGSPLFTGGAGSGES  363
            E   + GRFG GLPRVSDG +LF ++ +SK++ ++    R +I+ NGS+LF+G +G+GES
Sbjct  317  ELGEL-GRFGVGLPRVSDGQLLFQLNGISKLKETG----RMAIIHNGSALFSGNPGAGES  371

Query  364  EIRRYVLENDLVEAIIGLPTDMFYNTGIATYIWVLSNKKPADRAGQVQLIDAGSFWQKMR  423
             IR+YV+END +E+II LP D+FYNTGI+TYIW++++ K+++R G+VQL+DA++  +K R
Sbjct  372  LIRQYVIENDWLEGIIQLPNDLFYNTGISTYIWIITKDKSPERQGKVQLVDASNMYEKRR  431

Query  424  KSLGSKRKEMSDEHIATVTRLFGDFTEAEMVTVLDAAGVPQGEPVLVTSTDPQPVAPEGG  483
            K++G KR ++S+     + + +G+F + E    L+ + V                     
Sbjct  432  KNIGEKRVDISEACREMIVQAYGEFNDKE--YYLGDGTVE--------------------  469

Query  484  RLKRVPIARIFDNADFGYTTITVERPQRDEAGNVVLGVkgkqkgkpqpDTSLRDTENVPL  543
                   ++I+ N  FG+T +T+ERPQRDE G++V     K++G    DT+LRDTE++PL
Sbjct  470  -------SKILKNESFGFTRVTIERPQRDENGDIVY----KKNGSKSVDTNLRDTEDIPL  518

Query  544  KDDIDAYFQREVLPHAPDAWIDPDKTKVGYEIPFNRHFYVFEPPRSLATIDEELKAVSAR  603
             +DI+ YF+RE+LP   DAW+D  K K+GYEIPF R FY + PP +   I E +K +   
Sbjct  519  TEDINEYFEREILPFNQDAWMDRKKDKIGYEIPFTRLFYKYTPPEPSEVISERIKQLEES  578

Query  604  IMAMLGELA  612
            I+  +  L+
Sbjct  579  IIKNFQALS  587

28) hsdM3 in NC_016783


> NC_002953_R1|4|G3|49484939|YP_042160.1|Staphylococcus_aureus_subsp._aureus_MSSA476|-|4742..6529|-|SAS0027|type 
I restriction 
enzyme methylase
Length=595

 Score =  413 bits (1554),  Expect = 2e-116, Method: Compositional matrix adjust.
 Identities = 258/587 (44%), Positives = 397/587 (68%), Gaps = 42/587 (7%)

Query  5    GSFIWGTADILRGPYKASQYGNVILPMTILRRLDCVLEEHRTTIEPLVERFGSNPELLSA  64
            +++IW  ADILRG YK+ +YG+VILPMT+++RL+  L   R  +    E   S  +++  
Sbjct  18   ANLIWNVADILRGLYKPHEYGKVILPMTVIKRLHDTLLKTRDKVLKTAENTQSINDVMRE  77

Query  65   QVQR-ATSLPFYNTSPWTLKTLLGDPKGIEANLKHYVNGFSDNM-DVFERFKLADEIATM  122
            ++ + A++ +FYNTS  T+ TLL+DP  IE+N++ Y+NGFS+NM D+++ FK+  EI+TM
Sbjct  78   RLLKNASGYSFYNTSLYTFETLLADPANIESNFRAYLNGFSENMQDILNNFKFDVEITTM  137

Query  123  AEKNILYIVVERFSNID--LHPKTVTNAEMGDLYEYLIRTFNESSNEAPGEHFTPRDAIR  180
            A++++L+ V++ F++ D  L P  +T+++MG ++E L+R F+ES NE +G HFT+RD I 
Sbjct  138  ADNDVLFYVIQEFNKADAYLGPDKMTSTDMGYVFEELVRKFSESYNEEAGAHFTSRDIIY  197

Query  181  LLVDLVFAGDDEALSTPGAIRSIYDPTVGTGGMLSIAEEHLIGSSDRLGLNPQAQLRLYG  240
            L+ DL++  D ++L     ++++YD T+GT+ MLS   E++       ++N  A++  +G
Sbjct  198  LMTDLLLIEDKDTLFKEHVFKTVYDQTMGTSQMLSAMTERI------HDMNDTAEVATFG  251

Query  241  QEWNDHSYAVCKSDLLIKGYDSSNIQLGDTLADDKFAGQTFDYCMSNPPYGDDWKASQSA  300
            QE N ++YA+ K+D +I+G D+ N+ LG TL+ D+F G TFDYC+SNPP+G DWK  Q A
Sbjct  252  QELNPETYAISKADTMIRGGDPENMALGSTLTSDRFEGFTFDYCISNPPFGVDWKKDQKA  311

Query  301  VMEDLKELGSSSRFYAGGDKPKQNVPAVSDGQMLFLQHVVNKLRPKVKGGGRGGIVMNGS  360
            V  +  ELG  +RF  G       +P VSDGQ+LF  + ++KL    K  GR +I+ NGS
Sbjct  312  VKAE-HELGELGRFGVG-------LPRVSDGQLLFQLNGISKL----KETGRMAIIHNGS  359

Query  361  PLFNGTAESGPSNIRKWLLEHDLIDAIIALPTDMFYNTGIATYIWIVDNNKPIERQGKVQ  420
            +LF+G + +G S IR+ ++E+D +++II LP D+FYNTGI+TYIWI+ ++K+ ERQGKVQ
Sbjct  360  ALFSGNPGAGESLIRQYVIENDWLEGIIQLPNDLFYNTGISTYIWIITKDKSPERQGKVQ  419

Query  421  LIDGTEFYEKMRKKLGDKGREISEANRTTIVKLYDDYVDTE--------HCKIVPIEELA  472
            L+D+++ YEK RK++G+K  +ISEA R  IV+ Y+++ D E        + KI+  E ++
Sbjct  420  LVDASNMYEKRRKNIGEKRVDISEACREMIVQAYGEFNDKEYYLGDGTVESKILKNESFG  479

Query  473  YWLVTVERPRRDEHGEVITNARGKKQPDTALRDTERVPFTYGGNTQGDGGQQETIQAYFD  532
            +  VT+ERP+RDE+G+++ +  G K  DT LRDTE +P+T            E I+ YF+
Sbjct  480  FTRVTIERPQRDENGDIVYKKNGSKSVDTNLRDTEDIPLT------------EDINEYFE  527

Query  533  AEVKPYVPDAWVDEKKTKIGYEIPFTRYFYHYQPPRPLEAIDAELHQ  579
             E+ P+  DAW+D KK KIGYEIPFTR FY Y PP P E I   + Q
Sbjct  528  REILPFNQDAWMDRKKDKIGYEIPFTRLFYKYTPPEPSEVISERIKQ  574

29) hsdM2 in NC_016789


> NC_002953_R1|4|G3|49484939|YP_042160.1|Staphylococcus_aureus_subsp._aureus_MSSA476|-|4742..6529|-|SAS0027|type 
I restriction 
enzyme methylase
Length=595

 Score =  413 bits (1554),  Expect = 2e-116, Method: Compositional matrix adjust.
 Identities = 258/587 (44%), Positives = 397/587 (68%), Gaps = 42/587 (7%)

Query  5    GSFIWGTADILRGPYKASQYGNVILPMTILRRLDCVLEEHRTTIEPLVERFGSNPELLSA  64
            +++IW  ADILRG YK+ +YG+VILPMT+++RL+  L   R  +    E   S  +++  
Sbjct  18   ANLIWNVADILRGLYKPHEYGKVILPMTVIKRLHDTLLKTRDKVLKTAENTQSINDVMRE  77

Query  65   QVQR-ATSLPFYNTSPWTLKTLLGDPKGIEANLKHYVNGFSDNM-DVFERFKLADEIATM  122
            ++ + A++ +FYNTS  T+ TLL+DP  IE+N++ Y+NGFS+NM D+++ FK+  EI+TM
Sbjct  78   RLLKNASGYSFYNTSLYTFETLLADPANIESNFRAYLNGFSENMQDILNNFKFDVEITTM  137

Query  123  AEKNILYIVVERFSNID--LHPKTVTNAEMGDLYEYLIRTFNESSNEAPGEHFTPRDAIR  180
            A++++L+ V++ F++ D  L P  +T+++MG ++E L+R F+ES NE +G HFT+RD I 
Sbjct  138  ADNDVLFYVIQEFNKADAYLGPDKMTSTDMGYVFEELVRKFSESYNEEAGAHFTSRDIIY  197

Query  181  LLVDLVFAGDDEALSTPGAIRSIYDPTVGTGGMLSIAEEHLIGSSDRLGLNPQAQLRLYG  240
            L+ DL++  D ++L     ++++YD T+GT+ MLS   E++       ++N  A++  +G
Sbjct  198  LMTDLLLIEDKDTLFKEHVFKTVYDQTMGTSQMLSAMTERI------HDMNDTAEVATFG  251

Query  241  QEWNDHSYAVCKSDLLIKGYDSSNIQLGDTLADDKFAGQTFDYCMSNPPYGDDWKASQSA  300
            QE N ++YA+ K+D +I+G D+ N+ LG TL+ D+F G TFDYC+SNPP+G DWK  Q A
Sbjct  252  QELNPETYAISKADTMIRGGDPENMALGSTLTSDRFEGFTFDYCISNPPFGVDWKKDQKA  311

Query  301  VMEDLKELGSSSRFYAGGDKPKQNVPAVSDGQMLFLQHVVNKLRPKVKGGGRGGIVMNGS  360
            V  +  ELG  +RF  G       +P VSDGQ+LF  + ++KL    K  GR +I+ NGS
Sbjct  312  VKAE-HELGELGRFGVG-------LPRVSDGQLLFQLNGISKL----KETGRMAIIHNGS  359

Query  361  PLFNGTAESGPSNIRKWLLEHDLIDAIIALPTDMFYNTGIATYIWIVDNNKPIERQGKVQ  420
            +LF+G + +G S IR+ ++E+D +++II LP D+FYNTGI+TYIWI+ ++K+ ERQGKVQ
Sbjct  360  ALFSGNPGAGESLIRQYVIENDWLEGIIQLPNDLFYNTGISTYIWIITKDKSPERQGKVQ  419

Query  421  LIDGTEFYEKMRKKLGDKGREISEANRTTIVKLYDDYVDTE--------HCKIVPIEELA  472
            L+D+++ YEK RK++G+K  +ISEA R  IV+ Y+++ D E        + KI+  E ++
Sbjct  420  LVDASNMYEKRRKNIGEKRVDISEACREMIVQAYGEFNDKEYYLGDGTVESKILKNESFG  479

Query  473  YWLVTVERPRRDEHGEVITNARGKKQPDTALRDTERVPFTYGGNTQGDGGQQETIQAYFD  532
            +  VT+ERP+RDE+G+++ +  G K  DT LRDTE +P+T            E I+ YF+
Sbjct  480  FTRVTIERPQRDENGDIVYKKNGSKSVDTNLRDTEDIPLT------------EDINEYFE  527

Query  533  AEVKPYVPDAWVDEKKTKIGYEIPFTRYFYHYQPPRPLEAIDAELHQ  579
             E+ P+  DAW+D KK KIGYEIPFTR FY Y PP P E I   + Q
Sbjct  528  REILPFNQDAWMDRKKDKIGYEIPFTRLFYKYTPPEPSEVISERIKQ  574

30) Mspyr1_52870 in NC_014814


> NC_002953_R1|4|G3|49484939|YP_042160.1|Staphylococcus_aureus_subsp._aureus_MSSA476|-|4742..6529|-|SAS0027|type 
I restriction 
enzyme methylase
Length=595

 Score =  412 bits (1552),  Expect = 2e-116, Method: Compositional matrix adjust.
 Identities = 253/597 (43%), Positives = 393/597 (66%), Gaps = 38/597 (6%)

Query  1    MSKLGNFVWGIADQLRGVYKPHQYGGVILPFTILRRLDCTLEPTREEV---RELAEKYSG  57
            + K +N++W +AD LRG+YKPH+YG VILP T+++RL+ TL  TR+ V    E ++  ++
Sbjct  14   VQKQANLIWNVADILRGLYKPHEYGKVILPMTVIKRLHDTLLKTRDKVLKTAENTQSIND  73

Query  58   GALDVQVKRKTGLAFYNTSPFDFKLLLKDPEGLRANLMDYITGFSANI-DVFERFKFENE  116
               +  +K  +G +FYNTS + F  LL DP  + +N+  Y+ GFS N+ D+++ FKF+ E
Sbjct  74   VMRERLLKNASGYSFYNTSLYTFETLLADPANIESNFRAYLNGFSENMQDILNNFKFDVE  133

Query  117  LATLDEKNRLYLVTSQFAEVD--LHPNSVSNAEMGDLFEHLIYKFAEASNEEAGEHYTPR  174
            ++T+ +++ L+ V  +F   D  L P+ +++++MG +FE+L+ KF+E+ NEEAG H+T+R
Sbjct  134  ITTMADNDVLFYVIQEFNKADAYLGPDKMTSTDMGYVFEELVRKFSESYNEEAGAHFTSR  193

Query  175  DAIRLMVDLLFAEDNVALLEPGTVRTIYDPTAGTGGMLSVAEERLLERNPGARLRLYGQE  234
            D I LM DLL+ ED+ +L+     +T+YD T GT+ MLS   ER+ + N  A +  +GQE
Sbjct  194  DIIYLMTDLLLIEDKDTLFKEHVFKTVYDQTMGTSQMLSAMTERIHDMNDTAEVATFGQE  253

Query  235  INDQSYAICKSDMIAKGQDVGNIKLGDTLEDDLFFDRTFDFCMSNPPYGVDWKASQKSVK  294
            +N ++YAI K+D + +G D  N+ LG TL  D F + TFD+C+SNPP+GVDWK  QK+VK
Sbjct  254  LNPETYAISKADTMIRGGDPENMALGSTLTSDRFEGFTFDYCISNPPFGVDWKKDQKAVK  313

Query  295  KE-ALASNSRFSHGLPSIGDGQMLFLSHLASKMRPAHDGGGRAGIVLNGSPLFNGAAESG  353
             E  L+  +RF+ GLP ++DGQ+LF  +  SK++ +    GR +I+ NGS+LF+G + +G
Sbjct  314  AEHELGELGRFGVGLPRVSDGQLLFQLNGISKLKET----GRMAIIHNGSALFSGNPGAG  369

Query  354  PSLIRQWLLETDLLEAIVALPTNMFFNTGIATYIWILDNAKRTERAGKIQLIDATSFWTK  413
             SLIRQ ++E D LE+I+ LP ++F+NTGI+TYIWI+ + K  ER GK+QL+DA++   K
Sbjct  370  ESLIRQYVIENDWLEGIIQLPNDLFYNTGISTYIWIITKDKSPERQGKVQLVDASNMYEK  429

Query  414  MRKSLGSKNRELDADARDQILALYDSFDEGDPDY--------SKVFTANDFGYWSVTVER  465
             RK++G K  ++    R+ I+  Y+ F+  D +Y        SK++  + FG+  VT+ER
Sbjct  430  RRKNIGEKRVDISEACREMIVQAYGEFN--DKEYYLGDGTVESKILKNESFGFTRVTIER  487

Query  466  PLRTETGKVSTDRKGNPKPDAKLRDTENIPFTYGGNTAGDAARAETIEAYFEAEVLPHVP  525
            P R E G +   ++G+   D++LRDTE+IP+T            E I+ YFE E+LP   
Sbjct  488  PQRDENGDIVYKKNGSKSVDTNLRDTEDIPLT------------EDINEYFEREILPFNQ  535

Query  526  DAWVDVAKTKVGYEIPFARHFYKYVPPRP---LAEIDSDLDKQVAKILELL--REVE  577
            DAW+D  K K+GYEIPF+R FYKY PP P   ++E   +L+  + K ++ L  +EV+
Sbjct  536  DAWMDRKKDKIGYEIPFTRLFYKYTPPEPSEVISERIKQLEESIIKNFQALSGKEVD  592

31) hsdM in NC_008271


> NC_002953_R1|4|G3|49484939|YP_042160.1|Staphylococcus_aureus_subsp._aureus_MSSA476|-|4742..6529|-|SAS0027|type 
I restriction 
enzyme methylase
Length=595

 Score =  406 bits (1528),  Expect = 2e-114, Method: Compositional matrix adjust.
 Identities = 256/590 (44%), Positives = 391/590 (67%), Gaps = 34/590 (5%)

Query  1    MSKLGNFVWGIADQLRGVYKPHQYGGVILPFTVLRRLDCILEPTRDEVRALATKYADGAL  60
            + K +N++W +AD LRG+YKPH+YG VILP TV++RL+  L  TRD V   A + +++  
Sbjct  14   VQKQANLIWNVADILRGLYKPHEYGKVILPMTVIKRLHDTLLKTRDKVLKTAEN-TQSIN  72

Query  61   DVQ----VKRKTGLAFYNTSPFDFKHLLEDPEGLRANLVDYITGFSANI-DVFERFKFEN  115
            DV     +K  +G +FYNTS + F  LL DP  + +N+  Y+ GFS N+ D+++ FKF+ 
Sbjct  73   DVMRERLLKNASGYSFYNTSLYTFETLLADPANIESNFRAYLNGFSENMQDILNNFKFDV  132

Query  116  ELATLDEKNRLYLVTSQFADVD--LHPDVVSNAEMGDLFEHLIYKFAEASNEEAGEHYTP  173
            E++T+ +++ L+ V  +F   D  L PD +++++MG +FE+L+ KF+E+ NEEAG H+T+
Sbjct  133  EITTMADNDVLFYVIQEFNKADAYLGPDKMTSTDMGYVFEELVRKFSESYNEEAGAHFTS  192

Query  174  RDAIRLMVDLLFAEDNAALLEPGTVRTIYDPTAGTGGMLSVAEERLLERNPDARLRLYGQ  233
            RD I LM DLL+ ED+ +L+     +T+YD T GT+ MLS   ER+ + N  A +  +GQ
Sbjct  193  RDIIYLMTDLLLIEDKDTLFKEHVFKTVYDQTMGTSQMLSAMTERIHDMNDTAEVATFGQ  252

Query  234  EINDQSYAICKSDMIAKGQDVGNIKLGDTLAEDQFFDRTFDFCMSNPPYGVDWKASQEAV  293
            E+N ++YAI K+D + +G D  N+ LG TL+ D+F + TFD+C+SNPP+GVDWK  Q AV
Sbjct  253  ELNPETYAISKADTMIRGGDPENMALGSTLTSDRFEGFTFDYCISNPPFGVDWKKDQKAV  312

Query  294  KKE-ALAQNSRFSHGLPAVGDGQMLFLSHLASKMRPKHDGGGRAGIVLNGSPLFNGAAES  352
            K E  L++ +RF+ GLP V+DGQ+LF  +  SK++      GR +I+ NGS+LF+G + +
Sbjct  313  KAEHELGELGRFGVGLPRVSDGQLLFQLNGISKLK----ETGRMAIIHNGSALFSGNPGA  368

Query  353  GPSKIRQWLLKSDLVEAIIALPTNMFFNTGIATYIWILDNTKRPEREGKVQLIDATPFWS  412
            G S IRQ ++ +D +E+II LP ++F+NTGI+TYIWI+ + K PER+GKVQL+DA+    
Sbjct  369  GESLIRQYVIENDWLEGIIQLPNDLFYNTGISTYIWIITKDKSPERQGKVQLVDASNMYE  428

Query  413  KMRKSLGAKSRELDAGARDRILALYDAYDEAD------PAYSKIFTSDDFGYWTITVEQP  466
            K RK++G K  ++  + R+ I+  Y+ +++ +         SKI+ ++ FG+  +T+E+P
Sbjct  429  KRRKNIGEKRVDISEACREMIVQAYGEFNDKEYYLGDGTVESKILKNESFGFTRVTIERP  488

Query  467  LLDEDGMPVTDRSGNPKPDTKKRDTENIPFTYGGNTEGEAGRTATIKAYFEAEVLPHVHD  526
              DE+G  V  ++G+   DT+ RDTE+IP+            T  I+ YFE E+LP  +D
Sbjct  489  QRDENGDIVYKKNGSKSVDTNLRDTEDIPL------------TEDINEYFEREILPFNQD  536

Query  527  AWIDAKKTRIGYEIPFTRHFYKYVPPRP---IAEIDADLEKQVAKIMELL  573
            AW+D KK +IGYEIPFTR FYKY PP P   I+E   +LE  + K  + L
Sbjct  537  AWMDRKKDKIGYEIPFTRLFYKYTPPEPSEVISERIKQLEESIIKNFQAL  586

32) Sgly_0845 in NC_015172


> NC_002953_R1|4|G3|49484939|YP_042160.1|Staphylococcus_aureus_subsp._aureus_MSSA476|-|4742..6529|-|SAS0027|type 
I restriction 
enzyme methylase
Length=595

 Score =  405 bits (1524),  Expect = 4e-114, Method: Compositional matrix adjust.
 Identities = 263/579 (46%), Positives = 393/579 (68%), Gaps = 48/579 (8%)

Query  7    KADLIWKVADLLRGDYKQSDYGKVILPMTVLRRLDCVLEPTKQKVLDYLPKVESLKESAK  66
            +A+LIW+VAD+LRG YK  +YGKVILPMTV++RL+  L  T++KVL    + +S+++  +
Sbjct  17   QANLIWNVADILRGLYKPHEYGKVILPMTVIKRLHDTLLKTRDKVLKTAENTQSINDVMR  76

Query  67   DIALNKIAGFNFHNRSQLNFDKLIADPNNVSVNLRNYINGFSSSAREIIEYFNFDDHIDR  126
            +  L++ +G++F N S   F+ L+ADP N+  N+R Y+NGFS + ++I++ F+FD +I  
Sbjct  77   ERLLKNASGYSFYNTSLYTFETLLADPANIESNFRAYLNGFSENMQDILNNFKFDVEITT  136

Query  127  MDDPKTDILFRVLKAFQE----IGLTDMDSMEMGYVFEDLIRRFAEQSNETAGEHFTPRE  182
            M D   D+LF V++ F+     +G   M S +MGYVFE+L+R+F+E  NE AG HFT+R+
Sbjct  137  MAD--NDVLFYVIQEFNKADAYLGPDKMTSTDMGYVFEELVRKFSESYNEEAGAHFTSRD  194

Query  183  VIRLMVNLLFIEDKDILTQEGIVKTLYDPACGTGGMLSVGEQYVKELNPKAELKVFGQEI  242
            +I LM +LL+IEDKD L +E + KT+YD + GT+ MLS   + + ++N  AE+  FGQE+
Sbjct  195  IIYLMTDLLLIEDKDTLFKEHVFKTVYDQTMGTSQMLSAMTERIHDMNDTAEVATFGQEL  254

Query  243  NPESYAICKSDMLIKGQNPSNIKFGNTFTVDGLEEEKFDYMLSNPPFGVDWkkaekiika  302
            NPE+YAI K+D +I+G +P N+ +G+T+T D +E   FDY +SNPPFGVDWKK +K +KA
Sbjct  255  NPETYAISKADTMIRGGDPENMALGSTLTSDRFEGFTFDYCISNPPFGVDWKKDQKAVKA  314

Query  303  eaDNKGMNGRFGAGLPRINDGSLLFLQHMISKMKLSGTRIGIVFNGSPLFTGAAESGESN  362
            E +   + GRFG GLPR++DG LLF  + ISK+K +G R++I+ NGS+LF+G + +GES 
Sbjct  315  EHELGEL-GRFGVGLPRVSDGQLLFQLNGISKLKETG-RMAIIHNGSALFSGNPGAGESL  372

Query  363  IRKWIIENDWLEAVIALPDQLFYNTGISTYIWIINNSKSEERKGKVQLINATGAKDEELT  422
            IR+ +IENDWLE++I LP++LFYNTGISTYIWII + KS ER+GKVQL++A+        
Sbjct  373  IRQYVIENDWLEGIIQLPNDLFYNTGISTYIWIITKDKSPERQGKVQLVDASN-------  425

Query  423  KEGKLDFNRFWQKMDRSLGDKRKKIAENGNTKGIGFITQLYGNFEENEF--------VKI  474
                       +K  +++G+KR  I+E         I Q YG+F+++E+         KI
Sbjct  426  ---------MYEKRRKNIGEKRVDISEACREM----IVQAYGEFNDKEYYLGDGTVESKI  472

Query  475  YPNEFFGYWRITVEQPMKENSKVV--KSKGQPKPDTSLRDYENIPFLKKGSDGNLIPQTI  532
              NE FG+ R+T+E+P ++++  +  K +G    DT+LRD E+IP          + + I
Sbjct  473  LKNESFGFTRVTIERPQRDENGDIVYKKNGSKSVDTNLRDTEDIP----------LTEDI  522

Query  533  EEYFETEVKPHLLEAWIDHSKTKIGYEINFTKYFYEFKP  571
            +EYFE E+ P   +AW+D+ K KIGYEI FT+ FY + P
Sbjct  523  NEYFEREILPFNQDAWMDRKKDKIGYEIPFTRLFYKYTP  561

33) CC_0620 in NC_002696


> NC_002953_R1|4|G3|49484939|YP_042160.1|Staphylococcus_aureus_subsp._aureus_MSSA476|-|4742..6529|-|SAS0027|type 
I restriction 
enzyme methylase
Length=595

 Score =  404 bits (1519),  Expect = 1e-113, Method: Compositional matrix adjust.
 Identities = 258/614 (43%), Positives = 399/614 (65%), Gaps = 40/614 (6%)

Query  1    MNHQSLSAFIWSVADLLRGDYKQSDYGKVILPFTVLRRLDCVLEPTKAAVL-AEHEKRAA  59
            +N Q  + +IW+VAD+LRG YK  +YGKVILP TV++RL+  L  T+  VL + ++ ++ 
Sbjct  12   INVQKQANLIWNVADILRGLYKPHEYGKVILPMTVIKRLHDTLLKTRDKVLKTAENTQSI  71

Query  60   QGVDPEPFLRRVSGAGFYNTHKMDLTRVLGDADNVAANLYAYLQAFSPAVRDIFERFEFH  119
            ++V  E +L+  SG +FYNT    +  +L+D+ N+ +N+ AYL++FS  ++DI++ F F+
Sbjct  72   NDVMRERLLKNASGYSFYNTSLYTFETLLADPANIESNFRAYLNGFSENMQDILNNFKFD  131

Query  120  AQIERLAKAGLLYMVAEKFTRID--LHPEAVDNHQMGLVFEELIRKFAELSNETAGEHFT  177
             +I  +A  ++L+ V + F + D  L P+ + + +MG VFEEL+RKF+E  NE AG HFT
Sbjct  132  VEITTMADNDVLFYVIQEFNKADAYLGPDKMTSTDMGYVFEELVRKFSESYNEEAGAHFT  191

Query  178  PREVIRLMVELIFVEDDAALSEPGVVRTIYDPTAGTGGMLSVAEERLLQQNPGAKLSMYG  237
            +R++I LM +L+++ED  +L    V +T+YD T GT+ MLS   ER+ + N  A ++ +G
Sbjct  192  SRDIIYLMTDLLLIEDKDTLFKEHVFKTVYDQTMGTSQMLSAMTERIHDMNDTAEVATFG  251

Query  238  QELNPESYAICKADMLIKGQPVDNIVFGNTLSDDGHHAAKFDYMLSNPPFGVEWKKVEKI  297
            QELNPE+YAI KAD +I+G   +N+ +G+TL+ D  ++  FDY +SNPPFGV+WKK +K 
Sbjct  252  QELNPETYAISKADTMIRGGDPENMALGSTLTSDRFEGFTFDYCISNPPFGVDWKKDQKA  311

Query  298  VRAEAEQQGYNGRFGPGLPRVSDGSllfllhllSKMRPAVDGGSRFGIVLNGSPLFTGGA  357
            V+AE E     GRFG GLPRVSDG LLF L+ +SK++ +    +R +I+ NGS+LF+G +
Sbjct  312  VKAEHELGE-LGRFGVGLPRVSDGQLLFQLNGISKLKET----GRMAIIHNGSALFSGNP  366

Query  358  GSGESEIRRHLLESDLVEAIVALPTDMFYNTGIATYVWIVSNKKPAARRGKLQLIDASGF  417
            G+GES IR+ ++E+D +E+I+ LP D+FYNTGI+TY+WI+++ K++ R+GK+QL+DAS  
Sbjct  367  GAGESLIRQYVIENDWLEGIIQLPNDLFYNTGISTYIWIITKDKSPERQGKVQLVDASNM  426

Query  418  WRKMRKSLGSKRKEMGEDDIAAITRLFGAFVEAELASVFDAEGKPVDKVIVEAGSAPPVA  477
              K RK++G KR +++E     I + +G F + E    + ++G  V+             
Sbjct  427  YEKRRKNIGEKRVDISEACREMIVQAYGEFNDKEY---YLGDG-TVE-------------  469

Query  478  PEGGKVKLAPLSKILPNSAFGYRTITVERPLVDEAGKPVLGQKGKNKGKPQADSARRDTE  537
                       SKIL N +FG+  +T+ERP  DE G  V     K++G    D+  RDTE
Sbjct  470  -----------SKILKNESFGFTRVTIERPQRDENGDIVY----KKNGSKSVDTNLRDTE  514

Query  538  NVPLSEDVETYFAREVLPHAPDAWIDADKTKTGYEIPFNRHFYVFEPPRDLAQIDADLRA  597
            ++PL+ED++ YF RE+LP   DAW+D  K K GYEIPF R FY + PP     I   ++ 
Sbjct  515  DIPLTEDINEYFEREILPFNQDAWMDRKKDKIGYEIPFTRLFYKYTPPEPSEVISERIKQ  574

Query  598  VTDQIKAMIAELAA  611
            + + I   +  L++
Sbjct  575  LEESIIKNFQALSG  588

34) CCNA_00656 in NC_011916


> NC_002953_R1|4|G3|49484939|YP_042160.1|Staphylococcus_aureus_subsp._aureus_MSSA476|-|4742..6529|-|SAS0027|type 
I restriction 
enzyme methylase
Length=595

 Score =  404 bits (1521),  Expect = 8e-114, Method: Compositional matrix adjust.
 Identities = 258/614 (43%), Positives = 399/614 (65%), Gaps = 40/614 (6%)

Query  20   MNHQSLSAFIWSVADLLRGDYKQSDYGKVILPFTVLRRLDCVLEPTKAAVL-AEHEKRAA  78
            +N Q  + +IW+VAD+LRG YK  +YGKVILP TV++RL+  L  T+  VL + ++ ++ 
Sbjct  12   INVQKQANLIWNVADILRGLYKPHEYGKVILPMTVIKRLHDTLLKTRDKVLKTAENTQSI  71

Query  79   QGVDPEPFLRRVSGAGFYNTHKMDLTRVLGDADNVAANLYAYLQAFSPAVRDIFERFEFH  138
            ++V  E +L+  SG +FYNT    +  +L+D+ N+ +N+ AYL++FS  ++DI++ F F+
Sbjct  72   NDVMRERLLKNASGYSFYNTSLYTFETLLADPANIESNFRAYLNGFSENMQDILNNFKFD  131

Query  139  AQIERLAKAGLLYMVAEKFTRID--LHPEAVDNHQMGLVFEELIRKFAELSNETAGEHFT  196
             +I  +A  ++L+ V + F + D  L P+ + + +MG VFEEL+RKF+E  NE AG HFT
Sbjct  132  VEITTMADNDVLFYVIQEFNKADAYLGPDKMTSTDMGYVFEELVRKFSESYNEEAGAHFT  191

Query  197  PREVIRLMVELIFVEDDAALSEPGVVRTIYDPTAGTGGMLSVAEERLLQQNPGAKLSMYG  256
            +R++I LM +L+++ED  +L    V +T+YD T GT+ MLS   ER+ + N  A ++ +G
Sbjct  192  SRDIIYLMTDLLLIEDKDTLFKEHVFKTVYDQTMGTSQMLSAMTERIHDMNDTAEVATFG  251

Query  257  QELNPESYAICKADMLIKGQPVDNIVFGNTLSDDGHHAAKFDYMLSNPPFGVEWKKVEKI  316
            QELNPE+YAI KAD +I+G   +N+ +G+TL+ D  ++  FDY +SNPPFGV+WKK +K 
Sbjct  252  QELNPETYAISKADTMIRGGDPENMALGSTLTSDRFEGFTFDYCISNPPFGVDWKKDQKA  311

Query  317  VRAEAEQQGYNGRFGPGLPRVSDGSllfllhllSKMRPAVDGGSRFGIVLNGSPLFTGGA  376
            V+AE E     GRFG GLPRVSDG LLF L+ +SK++ +    +R +I+ NGS+LF+G +
Sbjct  312  VKAEHELGE-LGRFGVGLPRVSDGQLLFQLNGISKLKET----GRMAIIHNGSALFSGNP  366

Query  377  GSGESEIRRHLLESDLVEAIVALPTDMFYNTGIATYVWIVSNKKPAARRGKLQLIDASGF  436
            G+GES IR+ ++E+D +E+I+ LP D+FYNTGI+TY+WI+++ K++ R+GK+QL+DAS  
Sbjct  367  GAGESLIRQYVIENDWLEGIIQLPNDLFYNTGISTYIWIITKDKSPERQGKVQLVDASNM  426

Query  437  WRKMRKSLGSKRKEMGEDDIAAITRLFGAFVEAELASVFDAEGKPVDKVIVEAGSAPPVA  496
              K RK++G KR +++E     I + +G F + E    + ++G  V+             
Sbjct  427  YEKRRKNIGEKRVDISEACREMIVQAYGEFNDKEY---YLGDG-TVE-------------  469

Query  497  PEGGKVKLAPLSKILPNSAFGYRTITVERPLVDEAGKPVLGQKGKNKGKPQADSARRDTE  556
                       SKIL N +FG+  +T+ERP  DE G  V     K++G    D+  RDTE
Sbjct  470  -----------SKILKNESFGFTRVTIERPQRDENGDIVY----KKNGSKSVDTNLRDTE  514

Query  557  NVPLSEDVETYFAREVLPHAPDAWIDADKTKTGYEIPFNRHFYVFEPPRDLAQIDADLRA  616
            ++PL+ED++ YF RE+LP   DAW+D  K K GYEIPF R FY + PP     I   ++ 
Sbjct  515  DIPLTEDINEYFEREILPFNQDAWMDRKKDKIGYEIPFTRLFYKYTPPEPSEVISERIKQ  574

Query  617  VTDQIKAMIAELAA  630
            + + I   +  L++
Sbjct  575  LEESIIKNFQALSG  588

35) Pnap_4916 in NC_008759


> NC_002953_R1|4|G3|49484939|YP_042160.1|Staphylococcus_aureus_subsp._aureus_MSSA476|-|4742..6529|-|SAS0027|type 
I restriction 
enzyme methylase
Length=595

 Score =  402 bits (1513),  Expect = 3e-113, Method: Compositional matrix adjust.
 Identities = 262/595 (45%), Positives = 398/595 (67%), Gaps = 36/595 (6%)

Query  9    ANFVWSVADLLRGDYKAADYGKVILPLTLLRRLDCVLEGTKEQVLEEHAKHKGEGDAPTS  68
            AN++W+VAD+LRG YK+ +YGKVILP+T+++RL+  L  T+++VL    + ++  D    
Sbjct  18   ANLIWNVADILRGLYKPHEYGKVILPMTVIKRLHDTLLKTRDKVLKTAENTQSINDVMR-  76

Query  69   LDRILKRKSKQAFYNTSPFTLQTLLDDQKHIRQNLTAYIGEFSADARDVFERFKFLERLV  128
             +R+LK  S  +FYNTS +T++TLL D  +I  N+ AY+  FS + +D+++ FKF   + 
Sbjct  77   -ERLLKNASGYSFYNTSLYTFETLLADPANIESNFRAYLNGFSENMQDILNNFKFDVEIT  135

Query  129  ELDDKDLLFLLMQKFASID--LHPDAVPNETMGLVFEELIRKFAEASNETAGEHFTPREV  186
             + D+D+LF ++Q F   D  L PD + +  MG VFEEL+RKF+E+ NE AG HFT+R++
Sbjct  136  TMADNDVLFYVIQEFNKADAYLGPDKMTSTDMGYVFEELVRKFSESYNEEAGAHFTSRDI  195

Query  187  IQLIVHCLFSGDSEALSKPGVVRSMYDPTAGTGGILSVGEAVARSINKSAKMVLFGQELN  246
            I L+ + L+  D ++L K  V +++YD T GT+ +LS      + +N +A +  FGQELN
Sbjct  196  IYLMTDLLLIEDKDTLFKEHVFKTVYDQTMGTSQMLSAMTERIHDMNDTAEVATFGQELN  255

Query  247  DESYAICKADMLIKGQDPKNIVRGNTLSADGFPDEKFDYGAANPPFGVDWKKVLDPIKTE  306
             E+YAI KAD +I+G DP N+  G+TL++D F +  FDY  +NPPFGVDWKK   ++K+E
Sbjct  256  PETYAISKADTMIRGGDPENMALGSTLTSDRFEGFTFDYCISNPPFGVDWKKDQKAVKAE  315

Query  307  HETKGFAGRFGPGLPRVSDGSLLFLMHLISKMRPAAEGGGRIGIVLNGSPLFTGDAGSGE  366
            HE   + GRFG GLPRVSDG LLF ++ ISK++ +    GR++I+ NGS+LF+G++G+GE
Sbjct  316  HELGEL-GRFGVGLPRVSDGQLLFQLNGISKLKET----GRMAIIHNGSALFSGNPGAGE  370

Query  367  SEIRRWLLENDMLEAIIALPNDIFFNTGIATYIFILDNDKKADRKGKVQLIDATRMYTKM  426
            S IR+ ++END LE+II LPND+F+NTGI+TYI I+ +DK ++R+GKVQL+DA+ MY K 
Sbjct  371  SLIRQYVIENDWLEGIIQLPNDLFYNTGISTYIWIITKDKSPERQGKVQLVDASNMYEKR  430

Query  427  KKSLGNKRVRITDEQISEIVGVYSAGAKDANFELEFKEPVKSTGGNPAEAPALRIVSKVF  486
            +K++G+KRV I++     IV  Y+          EF++     G+   E       SK++
Sbjct  431  RKNIGEKRVDISEACREMIVQAYG----------EFNDKEYYLGDGTVE-------SKIL  473

Query  487  ENKFFGYRKVTVDRPLaegktgkf--kkgekafDKDLRDTESVPLTESIDAYFKREVLPH  544
             N  FG+ +VT++RP  + + +    K+G K+ D +LRDTE +PLTE I+ YF RE+LP 
Sbjct  474  KNESFGFTRVTIERPQRDENGDIVYKKNGSKSVDTNLRDTEDIPLTEDINEYFEREILPF  533

Query  545  VPDAWVNKDVKDEKDGLPGKVGYEINFNRYFYVYKAPRKPAVIAEEILEMEKRFV  599
              DAW+++          +K+GYEI F R FY Y +P  + VI+E I ++E  ++
Sbjct  534  NQDAWMDRK--------KDKIGYEIPFTRLFYKYTPPEPSEVISERIKQLEESII  580

36) hsdM in NC_005042


> NC_002953_R1|4|G3|49484939|YP_042160.1|Staphylococcus_aureus_subsp._aureus_MSSA476|-|4742..6529|-|SAS0027|type 
I restriction 
enzyme methylase
Length=595

 Score =  400 bits (1504),  Expect = 2e-112, Method: Compositional matrix adjust.
 Identities = 241/584 (42%), Positives = 391/584 (67%), Gaps = 19/584 (3%)

Query  7    SAFIWSVAELLRDNYKKSDYGQVILAFTVLRRI-DCVLEAEKRGVCEKRTSHKAPSLKSK  65
            + +IW+VA++LR+ YK  +YG+VIL+ TV++R+ D +L +  + +     ++    +   
Sbjct  18   ANLIWNVADILRGLYKPHEYGKVILPMTVIKRLHDTLLKTRDKVLKTAENTQSINDVMRE  77

Query  66   AFRLNQPDVNSCSPSLLGLKEIILDEGSISKNINAYIQSFSPTIKGIFESFEFETHIDRL  125
             +  N ++ +  + SL  +  ++ D ++I  N+ AY+++FS  +++I+++F F+ +I  +
Sbjct  78   RLLKNASGYSFYNTSLYTFETLLADPANIESNFRAYLNGFSENMQDILNNFKFDVEITTM  137

Query  126  NKTNLLSQVTRKFTLID--LHPTTISNTEMGTIFEELIRKFAELSNDIQGEHFTPREVIN  183
               ++L  V + F   D  L P  +++T+MG +FEEL+RKF+E  N+  G HFT+R++I 
Sbjct  138  ADNDVLFYVIQEFNKADAYLGPDKMTSTDMGYVFEELVRKFSESYNEEAGAHFTSRDIIY  197

Query  184  LMVNLLFSKDKEALLAEDIVKSIYDPTAGTGGMLSVAEEHIKAINPSAKLIVSGQEINPE  243
            LM +LL+  DK++L+ E++ K++YD T GT+ MLS   E+I  +N +A +   GQE+NPE
Sbjct  198  LMTDLLLIEDKDTLFKEHVFKTVYDQTMGTSQMLSAMTERIHDMNDTAEVATFGQELNPE  257

Query  244  SYAICKADMLIRGQDINNICLGNTLSHDHHAKKKYDYMLSNPPFGVDWKKVQKEVKKEYR  303
            +YAI KAD +IRG D +N+ LG+TL+ D+     +DY +SNPPFGVDWKK QK VK E +
Sbjct  258  TYAISKADTMIRGGDPENMALGSTLTSDRFEGFTFDYCISNPPFGVDWKKDQKAVKAE-H  316

Query  304  DKGFSGRFGPGLPRVSDGSLLFLMHLISKMLPASKGGSRIGIVLSGSPMFTGSAGSGESE  363
            + G  GRFG GLPRVSDG LLF ++ ISK+    K  +R++I+ +GS++F+G++G+GES 
Sbjct  317  ELGELGRFGVGLPRVSDGQLLFQLNGISKL----KETGRMAIIHNGSALFSGNPGAGESL  372

Query  364  IRRYVLENDYVEAIIQLPQELFYNTAISTYIWIITNKKESSRKGKVQLIDCSTFSKKMRK  423
            IR+YV+END +E+IIQLP++LFYNT+ISTYIWIIT+ K + R+GKVQL+D S    K RK
Sbjct  373  IRQYVIENDWLEGIIQLPNDLFYNTGISTYIWIITKDKSPERQGKVQLVDASNMYEKRRK  432

Query  424  SLGSKRQELRDNEISEITKIFNSFKEVK---TEGKSICRILKTEELGYKLITVDRPKKDI  480
            ++G KR ++ +     I + +  F++      +G    +ILK E +G+  +T++RP++D 
Sbjct  433  NIGEKRVDISEACREMIVQAYGEFNDKEYYLGDGTVESKILKNESFGFTRVTIERPQRDE  492

Query  481  KGNVITIRKGKYKGSTQFDPELRDTESIPLSEPVDSYFKREILTHYPDAWINEDKTKIGY  540
            +G+++  +    +GS   D +LRDTE IPL+E ++ YF REIL    DAW++  K KIGY
Sbjct  493  NGDIVYKK----NGSKSVDTNLRDTEDIPLTEDINEYFEREILPFNQDAWMDRKKDKIGY  548

Query  541  EILFNRYFYNFPKIRSLEKINQELRDL----FKVFSTLSKQIIE  580
            EI F R FY++    + E I++ +++L    +K F +LS + ++
Sbjct  549  EIPFTRLFYKYTPPEPSEVISERIKQLEESIIKNFQALSGKEVD  592

37) BPSL0948 in NC_006350


> NC_002953_R1|4|G3|49484939|YP_042160.1|Staphylococcus_aureus_subsp._aureus_MSSA476|-|4742..6529|-|SAS0027|type 
I restriction 
enzyme methylase
Length=595

 Score =  398 bits (1499),  Expect = 4e-112, Method: Compositional matrix adjust.
 Identities = 263/615 (43%), Positives = 407/615 (67%), Gaps = 42/615 (6%)

Query  1    MNHQALSSFIWSVADLLRGDYKQSEYGRVILPFTVLRRLDCVLESTKSAVLAEFE-AKSK  59
            +N Q  +++IW+VAD+LRG YK  EYG+VILP TV++RL+  L  T+  VL   E ++S 
Sbjct  12   INVQKQANLIWNVADILRGLYKPHEYGKVILPMTVIKRLHDTLLKTRDKVLKTAENTQSI  71

Query  60   KGLNPEPFLLRIVGDAKFYNTSPLDLVKLLGDQDHIRQNLYAYIQAFSPAARDIFERFDF  119
            +++  E  LL+  ++  FYNTS   +  LL+D  +I  N+ AY+++FS   +DI++ F F
Sbjct  72   NDVMRER-LLKNASGYSFYNTSLYTFETLLADPANIESNFRAYLNGFSENMQDILNNFKF  130

Query  120  YTQVERLAKADLLYLVTEKFANID--LHPTAVDNAQMGLVFEELIRKFAEISNETAGEHF  177
              ++  +A  D+L+ V + F + D  L P  + +++MG VFEEL+RKF+E  NE AG HF
Sbjct  131  DVEITTMADNDVLFYVIQEFNKADAYLGPDKMTSTDMGYVFEELVRKFSESYNEEAGAHF  190

Query  178  TPREVIRLMVNLLFIEDDDVLTPGNAVVRAIYDPTAGTGGMLSVAGEFLLEHNPVARLRM  237
            T+R++I LM +LL+IED D L   + V +++YD T GT+ MLS   E + + N  A +  
Sbjct  191  TSRDIIYLMTDLLLIEDKDTLFKEH-VFKTVYDQTMGTSQMLSAMTERIHDMNDTAEVAT  249

Query  238  YGQELNDESYAICKADMLIKGQDVENIVAGNTLSDDGHAGRQFDYMLSNPPFGVEWKKVE  297
            +GQELN E+YAI KAD +I+G D EN+  G+TL+ D   G  FDY +SNPPFGV+WKK +
Sbjct  250  FGQELNPETYAISKADTMIRGGDPENMALGSTLTSDRFEGFTFDYCISNPPFGVDWKKDQ  309

Query  298  KTVRAEYEQKGFAGRFGPGLPRVSDGSMLFLLHLLSKMRPAQEGGSRFGIVLNGSPLFTG  357
            K+V+AE E   + GRFG GLPRVSDG +LF L+ +SK++ +    +R +I+ NGS+LF+G
Sbjct  310  KAVKAEHELGEL-GRFGVGLPRVSDGQLLFQLNGISKLKET----GRMAIIHNGSALFSG  364

Query  358  GAGSGESEIRRYVLENDLVEAIVGLPTDMFYNTGIATYVWILSNRKPETRKGFVQLIDAS  417
             +G+GES IR+YV+END +E+I+ LP D+FYNTGI+TY+WI+++ K+  R+G VQL+DAS
Sbjct  365  NPGAGESLIRQYVIENDWLEGIIQLPNDLFYNTGISTYIWIITKDKSPERQGKVQLVDAS  424

Query  418  SFWQKMRKSLGSKRREMSDEHIDTVTRLFGNFVEAELTTVFDAEGKELGRWVVPAGSNVP  477
            +  +K RK++G KR ++S+   + + + +G+F + E    + ++G               
Sbjct  425  NMYEKRRKNIGEKRVDISEACREMIVQAYGEFNDKEY---YLGDG---------------  466

Query  478  NVPAGGKVKSVPISRIFRNQEFGYTTITVERALRDEqgkvvlgvkgkqkgkpqADSSLRD  537
                         S+I++N+ FG+T +T+ER+ RDE      ++  K++G    D++LRD
Sbjct  467  ----------TVESKILKNESFGFTRVTIERPQRDE----NGDIVYKKNGSKSVDTNLRD  512

Query  538  TENVPLSDDIGVYFEREVLPHAPDAWIDEQKNKVGYEIPFNRHFYVFEPPRDLHTIDEEL  597
            TE++PL++DI  YFERE+LP   DAW+D +K+K+GYEIPF R FY + PP   + I E +
Sbjct  513  TEDIPLTEDINEYFEREILPFNQDAWMDRKKDKIGYEIPFTRLFYKYTPPEPSEVISERI  572

Query  598  KAVSANIMRMLEELA  612
            K +  +I++ ++ L+
Sbjct  573  KQLEESIIKNFQALS  587

38) Belba_0350 in NC_018010


> NC_002953_R1|4|G3|49484939|YP_042160.1|Staphylococcus_aureus_subsp._aureus_MSSA476|-|4742..6529|-|SAS0027|type 
I restriction 
enzyme methylase
Length=595

 Score =  395 bits (1486),  Expect = 4e-111, Method: Compositional matrix adjust.
 Identities = 249/598 (42%), Positives = 400/598 (67%), Gaps = 46/598 (7%)

Query  7    NLQSIINFIWTVADDVLINKFLENQYQDVILPMTVLRRLDLALEPTKDKVLQTHNEFKSK  66
            N+Q   N+IW VAD +L   +  ++Y  VILPMTV++RL+ +L  T+DKVL+T ++    
Sbjct  13   NVQKQANLIWNVAD-ILRGLYKPHEYGKVILPMTVIKRLHDTLLKTRDKVLKTAEN----  67

Query  67   IDNVSGLLTSEL--HGSGLAFYNTSPYTMKKLLDDPKNIDANFLDYLNGFSENVQDIISK  124
             +++++++   L  ++SG +FYNTS YT   LL DP NI++NF  YLNGFSEN+QDI+++
Sbjct  68   TQSINDVMRERLLKNASGYSFYNTSLYTFETLLADPANIESNFRAYLNGFSENMQDILNN  127

Query  125  FKFRNQLNTFEETGITFSLIEKFCNPKVELSPDKISPMAMGYMFEDLIRRFNEKTNAAAG  184
            FKF  ++ T  + ++ F +I+ F ++   L+PDK+++  MGY+FE+L+R+F+E  N  AG
Sbjct  128  FKFDVEITTMADNDVLFYVIQEFNKADAYLGPDKMTSTDMGYVFEELVRKFSESYNEEAG  187

Query  185  RHFTPREIIELMTHLVYLPVKDKIQKGTFL--VYDPCAGSGAMLTQSKLFATNPEGEIKS  242
             HFT+R+II LMT+L+ +  KD + K   +  VYD   G++ ML+      T+   +++ 
Sbjct  188  AHFTSRDIIYLMTDLLLIEDKDTLFKEHVFKTVYDQTMGTSQMLSA----MTERIHDMND  243

Query  243  TATFHLYGQENTGEMYATCKSDMLLKNEDPDKIKFGSTLSEYGFDPDLKFNFMLTNPPYG  302
            TA    +GQE   E YA  K+D +++  DP+++ +GSTL+   F+ ++ F++ ++NPP+G
Sbjct  244  TAEVATFGQELNPETYAISKADTMIRGGDPENMALGSTLTSDRFE-GFTFDYCISNPPFG  302

Query  303  TTWKQDQENLNVGTGKKVEIKD-RRFNLKIKNFKGELEETCLTSRSNDGQLMFMLHMLSK  361
              WK+DQ  ++       E+ +  RF + +             +R +DGQL+F L+ +SK
Sbjct  303  VDWKKDQKAVKAEH----ELGELGRFGVGL-------------PRVSDGQLLFQLNGISK  345

Query  362  MKDPKDGGSRIASIHNGSALFTGDAGSSESGIRQYILENDLLECIIQLPNDMFYNTGITT  421
            +K+     +R+A IHNGSALF+G++G++ES IRQY++END LE IIQLPND+FYNTGI+T
Sbjct  346  LKET----GRMAIIHNGSALFSGNPGAGESLIRQYVIENDWLEGIIQLPNDLFYNTGIST  401

Query  422  YIWLLTNVKEERRKGKVQLINASSEGFYQKMRKSLGSKRVELTANHIQIIQEMCFAFEEN  481
            YIW++T+ K   R+GKVQL++AS+   Y+K RK++G KRV+++    ++I +    F+++
Sbjct  402  YIWIITKDKSPERQGKVQLVDASN--MYEKRRKNIGEKRVDISEACREMIVQAYGEFNDK  459

Query  482  EY--------SKIFDNEDFGFYQITVHQPERDEKGNIIKDTKGKPKSDSTLKDTENVPMK  533
            EY        SKI+ NE FGF ++T+++P+RDE+G+I+   +G    D+ L+DTE++P+ 
Sbjct  460  EYYLGDGTVESKILKNESFGFTRVTIERPQRDENGDIVYKKNGSKSVDTNLRDTEDIPLT  519

Query  534  ESIADYFKREVLPFAPGAWYDKTKMKVGFEIPFTKYFYQYEPLRALSDIAADIMTLEQ  591
            E I +YF RE+LPF  +AW D+ K K+G+EIPFT+ FY+Y P  +   I+  I  LE+
Sbjct  520  EDINEYFEREILPFNQDAWMDRKKDKIGYEIPFTRLFYKYTPPEPSEVISERIKQLEE  577

39) TepiRe1_2393 in NC_019954


> NC_002953_R1|4|G3|49484939|YP_042160.1|Staphylococcus_aureus_subsp._aureus_MSSA476|-|4742..6529|-|SAS0027|type 
I restriction 
enzyme methylase
Length=595

 Score =  384 bits (1444),  Expect = 1e-107, Method: Compositional matrix adjust.
 Identities = 234/486 (49%), Positives = 344/486 (71%), Gaps = 22/486 (4%)

Query  5    QDKVNFIWTIAELLRGPYKKEQYGDVILPMAVLRRFDCVLAETKEEVLKAYEALKETGLQ  64
            Q + N+IW +A++LRG YK ++YG VILPM+V++R++  L  T++ VLK+ E  +     
Sbjct  15   QKQANLIWNVADILRGLYKPHEYGKVILPMTVIKRLHDTLLKTRDKVLKTAENTQSINDV  74

Query  65   NMDPVLNKISKQKFNNTSKYDFEKLLADPDNIASNLRNYVNGFSKNAREIIEYFDFDKQI  124
              + +L++ S   F NTS Y FE LLADP NI SN+R Y+NGFS N ++I++ F FD +I
Sbjct  75   MRERLLKNASGYSFYNTSLYTFETLLADPANIESNFRAYLNGFSENMQDILNNFKFDVEI  134

Query  125  TKLNDNNLLYLIVSEFNKID--LHPDAVSNMEMGYIFEELIRRFSE--HAEAGDHYTPRE  180
            T + DN++L+ ++ EFNK D  L PD +++ +MGY+FEEL+R+FSE  + EAG H+T+R+
Sbjct  135  TTMADNDVLFYVIQEFNKADAYLGPDKMTSTDMGYVFEELVRKFSESYNEEAGAHFTSRD  194

Query  181  VIRLMVNILLNEDKESLTTPGLVVTVYDCCAGTGGMLSVTEQYLKELNPGIQVELFGQEI  240
            +I LM ++LL EDK++L    +  TVYD   GT+ MLS   + + ++N   +V  FGQE+
Sbjct  195  IIYLMTDLLLIEDKDTLFKEHVFKTVYDQTMGTSQMLSAMTERIHDMNDTAEVATFGQEL  254

Query  241  NPQSYSICKSDMLIKGQDADNIILGDSFTEDGHKGKTFRYMLTNPPFGVEWKKAEKFIRE  300
            NP++Y+I K+D +I+G D++N+ LG ++T D   G TF Y ++NPPFGV+WKK +K ++ 
Sbjct  255  NPETYAISKADTMIRGGDPENMALGSTLTSDRFEGFTFDYCISNPPFGVDWKKDQKAVKA  314

Query  301  EYEKEGFDGRFGAGLPRISDGSLLFLQHLISKMKQDEKGSRIAIIFNGSPLFTGDAGSGE  360
            E E   + GRFG GLPR+SDG LLF  + ISK+K+    +R+AII NGS+LF+G++G+GE
Sbjct  315  EHELGEL-GRFGVGLPRVSDGQLLFQLNGISKLKE---TGRMAIIHNGSALFSGNPGAGE  370

Query  361  SEIRRWIIENDMLEGIIALPDQLFYNTGISTYIWIVTNRKNNDLMKGPARAGKIQLVNAV  420
            S IR+ +IEND LEGII LP++LFYNTGISTYIWI+T+       K+P R GK+QLV+A 
Sbjct  371  SLIRQYVIENDWLEGIIQLPNDLFYNTGISTYIWIITKD------KSPERQGKVQLVDAS  424

Query  421  DFYQKMRKSLGNKRNEISEEQIEEITRIYGEFKENEY--------CKIFDNEDFGYRKIV  472
            + Y+K RK++G+KR +ISE   E I + YGEF+++EY         KI+ NE FG+ ++ 
Sbjct  425  NMYEKRRKNIGEKRVDISEACREMIVQAYGEFNDKEYYLGDGTVESKILKNESFGFTRVT  484

Query  473  VERPLR  478
            +ERP R
Sbjct  485  IERPQR  490


 Score = 84.4 bits (301),  Expect = 2e-17, Method: Compositional matrix adjust.
 Identities = 43/77 (56%), Positives = 56/77 (73%), Gaps = 0/77 (0%)

Query  571  SEKDETADICLDAKGNPEPDPDLRDTENVPLKEDIHDYFEREVKPHVPDAWIDESKTKIG  630
            +++DE +DI    +G+   D +LRDTE++PL EDI++YFERE+ P   DAW+D  K KIG
Sbjct  488  PQRDENGDIVYKKNGSKSVDTNLRDTEDIPLTEDINEYFEREILPFNQDAWMDRKKDKIG  547

Query  631  YEIPFTRHFYKYEPLRP  647
            YEIPFTR FYKY P  P
Sbjct  548  YEIPFTRLFYKYTPPEP  564

40) TepRe1_2225 in NC_015519


> NC_002953_R1|4|G3|49484939|YP_042160.1|Staphylococcus_aureus_subsp._aureus_MSSA476|-|4742..6529|-|SAS0027|type 
I restriction 
enzyme methylase
Length=595

 Score =  384 bits (1444),  Expect = 1e-107, Method: Compositional matrix adjust.
 Identities = 234/486 (49%), Positives = 344/486 (71%), Gaps = 22/486 (4%)

Query  5    QDKVNFIWTIAELLRGPYKKEQYGDVILPMAVLRRFDCVLAETKEEVLKAYEALKETGLQ  64
            Q + N+IW +A++LRG YK ++YG VILPM+V++R++  L  T++ VLK+ E  +     
Sbjct  15   QKQANLIWNVADILRGLYKPHEYGKVILPMTVIKRLHDTLLKTRDKVLKTAENTQSINDV  74

Query  65   NMDPVLNKISKQKFNNTSKYDFEKLLADPDNIASNLRNYVNGFSKNAREIIEYFDFDKQI  124
              + +L++ S   F NTS Y FE LLADP NI SN+R Y+NGFS N ++I++ F FD +I
Sbjct  75   MRERLLKNASGYSFYNTSLYTFETLLADPANIESNFRAYLNGFSENMQDILNNFKFDVEI  134

Query  125  TKLNDNNLLYLIVSEFNKID--LHPDAVSNMEMGYIFEELIRRFSE--HAEAGDHYTPRE  180
            T + DN++L+ ++ EFNK D  L PD +++ +MGY+FEEL+R+FSE  + EAG H+T+R+
Sbjct  135  TTMADNDVLFYVIQEFNKADAYLGPDKMTSTDMGYVFEELVRKFSESYNEEAGAHFTSRD  194

Query  181  VIRLMVNILLNEDKESLTTPGLVVTVYDCCAGTGGMLSVTEQYLKELNPGIQVELFGQEI  240
            +I LM ++LL EDK++L    +  TVYD   GT+ MLS   + + ++N   +V  FGQE+
Sbjct  195  IIYLMTDLLLIEDKDTLFKEHVFKTVYDQTMGTSQMLSAMTERIHDMNDTAEVATFGQEL  254

Query  241  NPQSYSICKSDMLIKGQDADNIILGDSFTEDGHKGKTFRYMLTNPPFGVEWKKAEKFIRE  300
            NP++Y+I K+D +I+G D++N+ LG ++T D   G TF Y ++NPPFGV+WKK +K ++ 
Sbjct  255  NPETYAISKADTMIRGGDPENMALGSTLTSDRFEGFTFDYCISNPPFGVDWKKDQKAVKA  314

Query  301  EYEKEGFDGRFGAGLPRISDGSLLFLQHLISKMKQDEKGSRIAIIFNGSPLFTGDAGSGE  360
            E E   + GRFG GLPR+SDG LLF  + ISK+K+    +R+AII NGS+LF+G++G+GE
Sbjct  315  EHELGEL-GRFGVGLPRVSDGQLLFQLNGISKLKE---TGRMAIIHNGSALFSGNPGAGE  370

Query  361  SEIRRWIIENDMLEGIIALPDQLFYNTGISTYIWIVTNRKNNDLMKGPARAGKIQLVNAV  420
            S IR+ +IEND LEGII LP++LFYNTGISTYIWI+T+       K+P R GK+QLV+A 
Sbjct  371  SLIRQYVIENDWLEGIIQLPNDLFYNTGISTYIWIITKD------KSPERQGKVQLVDAS  424

Query  421  DFYQKMRKSLGNKRNEISEEQIEEITRIYGEFKENEY--------CKIFDNEDFGYRKIV  472
            + Y+K RK++G+KR +ISE   E I + YGEF+++EY         KI+ NE FG+ ++ 
Sbjct  425  NMYEKRRKNIGEKRVDISEACREMIVQAYGEFNDKEYYLGDGTVESKILKNESFGFTRVT  484

Query  473  VERPLR  478
            +ERP R
Sbjct  485  IERPQR  490


 Score = 84.4 bits (301),  Expect = 2e-17, Method: Compositional matrix adjust.
 Identities = 43/77 (56%), Positives = 56/77 (73%), Gaps = 0/77 (0%)

Query  571  SEKDETADICLDAKGNPEPDPDLRDTENVPLKEDIHDYFEREVKPHVPDAWIDESKTKIG  630
            +++DE +DI    +G+   D +LRDTE++PL EDI++YFERE+ P   DAW+D  K KIG
Sbjct  488  PQRDENGDIVYKKNGSKSVDTNLRDTEDIPLTEDINEYFEREILPFNQDAWMDRKKDKIG  547

Query  631  YEIPFTRHFYKYEPLRP  647
            YEIPFTR FYKY P  P
Sbjct  548  YEIPFTRLFYKYTPPEP  564

41) Mbar_A1016 in NC_007355


> NC_002953_R1|4|G3|49484939|YP_042160.1|Staphylococcus_aureus_subsp._aureus_MSSA476|-|4742..6529|-|SAS0027|type 
I restriction 
enzyme methylase
Length=595

 Score =  381 bits (1433),  Expect = 7e-107, Method: Compositional matrix adjust.
 Identities = 230/484 (48%), Positives = 357/484 (74%), Gaps = 19/484 (3%)

Query  5    QEKTSFIWSVADEVLRDDFKRGEYPDVILPFTVLRRLDCVLAPTKDKVLEYDKKLEGKIE  64
            Q ++++IW+VAD +LR+ +K  EY  VILP TV++RL+  L  T+DKVL    + ++  +
Sbjct  15   QKQANLIWNVAD-ILRGLYKPHEYGKVILPMTVIKRLHDTLLKTRDKVLKTAENTQSIND  73

Query  65   N-KNGALRHASGYSFYNTSPYDFEKLLAAPTSIGQNLRAYINGFSENMREVIDKFKLWGT  123
              ++  L++ASGYSFYNTS Y FE LLA P++I  N+RAY+NGFSENM++++++FK+   
Sbjct  74   VMRERLLKNASGYSFYNTSLYTFETLLADPANIESNFRAYLNGFSENMQDILNNFKFDVE  133

Query  124  IDTLEEKGLLFLLIQKFANVD--LHPDAVSNHEMGYIFEELIRKFNEQTNENPGEHFTPR  181
            I T+ ++++LF +IQ F + D  L PD +++ +MGY+FEEL+RKF+E  NE++G HFT+R
Sbjct  134  ITTMADNDVLFYVIQEFNKADAYLGPDKMTSTDMGYVFEELVRKFSESYNEEAGAHFTSR  193

Query  182  EVIRLMVNLLLSQDQEKLAQNHIVRTVYDPACGTGGMLTIAKEHILDHINPNANIKLFGQ  241
            ++I LM +LLL +D++ L ++H+ +TVYD + GT+ ML+   E+I +++N  A++  FGQ
Sbjct  194  DIIYLMTDLLLIEDKDTLFKEHVFKTVYDQTMGTSQMLSAMTERI-HDMNDTAEVATFGQ  252

Query  242  EVNDKTFAISKSDMLIKGDDKDADNIKPDSSFSKDGHAGETFDYILSNPPYGKDWKKEED  301
            E+N  T+AISK+D +I+G+D  ++N+  +S+++ D   G TFDY +SNPP+G DWKK++ 
Sbjct  253  ELNPETYAISKADTMIRGGD--PENMALGSTLTSDRFEGFTFDYCISNPPFGVDWKKDQK  310

Query  302  FIEKEAKKGYEGRFGAGLPRKSDGQLIFVQHMISKMKPTEEGGSRIAIVMNGSPLFTGDA  361
             +  E   G  GRFG GLPR SDGQL+F  + ISK+K T    +R+AI+ NGS+LF+G++
Sbjct  311  AVKAEHELGELGRFGVGLPRVSDGQLLFQLNGISKLKET----GRMAIIHNGSALFSGNP  366

Query  362  GSGESEIRRWIIENDWLEAIVALPNQLFYNTGINTYIWIITNRKDEQRRGKVQLINAADF  421
            G+GES IR+ +IENDWLE+I+ LPN+LFYNTGI+TYIWIIT+ K  +R+GKVQL++A++ 
Sbjct  367  GAGESLIRQYVIENDWLEGIIQLPNDLFYNTGISTYIWIITKDKSPERQGKVQLVDASNM  426

Query  422  YVKMRKSLGDKRNEISPSQIEEITKLHTDFKENEF--------VKIFDDEAFGYRKITVE  473
            Y K RK++G+KR +IS +  E I +   +F+++E+         KI+ +E+FG+ ++T+E
Sbjct  427  YEKRRKNIGEKRVDISEACREMIVQAYGEFNDKEYYLGDGTVESKILKNESFGFTRVTIE  486

Query  474  RPLR  477
            RP R
Sbjct  487  RPQR  490


 Score = 72.6 bits (256),  Expect = 9e-14, Method: Compositional matrix adjust.
 Identities = 56/164 (35%), Positives = 95/164 (58%), Gaps = 18/164 (10%)

Query  503  KKKKDLQEKAREEAEGRKVREEIINALSGMDANVFYTDREQFEKDLNAALKKADLKPATA  562
            K++K++ EK  + +E+   RE I++A +  + + +Y +    E  +   LK+  +    +
Sbjct  429  KRRKNIGEKRVDISEA--CREMIVQAYGEFNDKEYYLGDGTVESKI---LKNESF----G  479

Query  563  VKKSIFEALSESDENAETCKDKKGNNEADSQLKDTENVPLKEDIYTYFEREVKPHVPDAW  622
              +  +E  ++ DEN++    K+G++  D++L+DTE++PL EDI  YFERE+ P   DAW
Sbjct  480  FTRVTIER-PQRDENGDIVYKKNGSKSVDTNLRDTEDIPLTEDINEYFEREILPFNQDAW  538

Query  623  IDETTRDPKDGKVGKVGYEINFNRYFYKYEPPRALEDIEADINK  666
            +D         K +K+GYEI F R FYKY PP + E I   I++
Sbjct  539  MDR--------KKDKIGYEIPFTRLFYKYTPPEPSEVISERIKQ  574

42) SACTE_4308 in NC_015953


> NC_002953_R1|4|G3|49484939|YP_042160.1|Staphylococcus_aureus_subsp._aureus_MSSA476|-|4742..6529|-|SAS0027|type 
I restriction 
enzyme methylase
Length=595

 Score =  380 bits (1429),  Expect = 1e-106, Method: Compositional matrix adjust.
 Identities = 248/592 (42%), Positives = 395/592 (67%), Gaps = 33/592 (5%)

Query  5    GSFIWSIADQLRGPYRPNQYGTVVLPFTILRRLDCILEPDQATVRELAAKFENPNRLKVE  64
            +++IW++AD LRG Y+P++YG V+LP T+++RL+  L   +  V   A + ++ N +  E
Sbjct  18   ANLIWNVADILRGLYKPHEYGKVILPMTVIKRLHDTLLKTRDKVLKTAENTQSINDVMRE  77

Query  65   --VKKATGRTFYNTSNYSFanlladadgladnladYIDRFSADV-DVFEYFDFKKEILAL  121
              +K+A+G +FYNTS Y+F  LLAD+  +  N+  Y++ FS ++ D+++ F F  EI ++
Sbjct  78   RLLKNASGYSFYNTSLYTFETLLADPANIESNFRAYLNGFSENMQDILNNFKFDVEITTM  137

Query  122  EKAGLLREIVKSFGKID--LHPDVVSNSDMGDAFEYIIRKFNEAANETSGDHYTPRDAIR  179
               ++L  +++ F K D  L PD ++++DMG  FE ++RKF+E+ NE +G H+T+RD I 
Sbjct  138  ADNDVLFYVIQEFNKADAYLGPDKMTSTDMGYVFEELVRKFSESYNEEAGAHFTSRDIIY  197

Query  180  LLVDLLFAEKDVDLTEGGIIRSLYDPTAGTGGMLSLAEEHLLAENPGAKLGLYGQEYNPQ  239
            L+ DLL+ E    L    +++++YD T GT+ MLS   E++   N  A ++ +GQE NP+
Sbjct  198  LMTDLLLIEDKDTLFKEHVFKTVYDQTMGTSQMLSAMTERIHDMNDTAEVATFGQELNPE  257

Query  240  SYAICKSDLLAKGHDATNIAFGNTLTDDAFKGRQFDYCMSNPPYGVDWKQHAKAVKEERD  299
            +YAI K+D + +G D+ N+A+G+TLT D F G  FDYC+SNPP+GVDWK++ KAVK E++
Sbjct  258  TYAISKADTMIRGGDPENMALGSTLTSDRFEGFTFDYCISNPPFGVDWKKDQKAVKAEHE  317

Query  300  SAGPYGRFAPGLPATSDGQMLFLLHLVHKMRAPEDGGGRVGIVMNGSPLFSGAAESGPSN  359
              G  GRF+ GLP  SDGQ+LF L+ + K++      GR++I+ NGS+LFSG + +G S 
Sbjct  318  -LGELGRFGVGLPRVSDGQLLFQLNGISKLKET----GRMAIIHNGSALFSGNPGAGESL  372

Query  360  IRRWLLESDLVEAIVALPTNMFFNTGIATYIWILDNTKHPDRQGKVQLIDGTSFWTKMRK  419
            IR+ ++E+D +E+I+ LP ++F+NTGI+TYIWI+ + K P+RQGKVQL+D+++   K RK
Sbjct  373  IRQYVIENDWLEGIIQLPNDLFYNTGISTYIWIITKDKSPERQGKVQLVDASNMYEKRRK  432

Query  420  NLGAKGREISDADRAEVVRLYADYEDAD------PELSKVLRNDEFGYWMVTVERPLLGE  473
            N+G K  +IS+A R  +V+ Y++++D +         SK+L+N+ FG+  VT+ERP  +E
Sbjct  433  NIGEKRVDISEACREMIVQAYGEFNDKEYYLGDGTVESKILKNESFGFTRVTIERPQRDE  492

Query  474  GGNPVVSRKGDPKPDSKKRDTENVPFTYGGSTAGAAAEREVIQAYFDAEVKPHVPDAWID  533
             G+ V  ++G    D++ RDTE++P+T            E I+ YF+ E+ P   DAW+D
Sbjct  493  NGDIVYKKNGSKSVDTNLRDTEDIPLT------------EDINEYFEREILPFNQDAWMD  540

Query  534  WAKTKTGYEVPFTRHFYKYVPPRP---LAEIDADLEKQVAKILDLL--REVE  580
            + K K GYE+PFTR FYKY PP P   ++E   +LE  + K ++ L  +EV+
Sbjct  541  RKKDKIGYEIPFTRLFYKYTPPEPSEVISERIKQLEESIIKNFQALSGKEVD  592

43) BpOF4_03735 in NC_013791


> NC_002953_R1|4|G3|49484939|YP_042160.1|Staphylococcus_aureus_subsp._aureus_MSSA476|-|4742..6529|-|SAS0027|type 
I restriction 
enzyme methylase
Length=595

 Score =  378 bits (1421),  Expect = 7e-106, Method: Compositional matrix adjust.
 Identities = 231/488 (48%), Positives = 357/488 (74%), Gaps = 21/488 (4%)

Query  2    INFQDKVSFIWSIAEILRGPYKPEDYGKVILPLAVLRRFDCVLDSTKEEVLASAEKFASM  61
            IN Q + ++IW++A+ILRG YKP++YGKVILP++V++R++  L  T++ VL +AE+  S+
Sbjct  12   INVQKQANLIWNVADILRGLYKPHEYGKVILPMTVIKRLHDTLLKTRDKVLKTAENTQSI  71

Query  62   NEEAREPILNRVAKQNFHNTSKYDFNKLLSDSDNIADNLRDYINGFSKTARDIMDHFDLE  121
            N+  RE +L+  +  +F NTS Y F+ LL+D+ NI  N+R Y+NGFS   +DI+++F ++
Sbjct  72   NDVMRERLLKNASGYSFYNTSLYTFETLLADPANIESNFRAYLNGFSENMQDILNNFKFD  131

Query  122  RQIDKLETNNLLYLTIKRFSEID--LHPEVVSNVEMGYIFEELIRRFNE--NAEAGDHYT  177
             +I  +  N++L+  I+ F+  D  L P+ +++ +MGY+FEEL+R+F+E  N EAG H+T
Sbjct  132  VEITTMADNDVLFYVIQEFNKADAYLGPDKMTSTDMGYVFEELVRKFSESYNEEAGAHFT  191

Query  178  PREVIRLMTHLLFLHDDASILTKPGLTQTLYDCAAGTGGMGSVAQEYLASVNFSAQLEFF  237
            +R++I LMT+LL+++D  +++ K  + +T+YD + GT+ M S   E +  +N +A++  F
Sbjct  192  SRDIIYLMTDLLLIEDKDTLF-KEHVFKTVYDQTMGTSQMLSAMTERIHDMNDTAEVATF  250

Query  238  GQEINGESYAICKADILIKGADAKNIRLGNTLSNDQFPYDKFDYLISNPPYGVDWKSYQK  297
            GQE+N E+YAI KAD +I+G+D+ N+ LG+TL++D+F    FDY ISNPP+GVDWK  QK
Sbjct  251  GQELNPETYAISKADTMIRGGDPENMALGSTLTSDRFEGFTFDYCISNPPFGVDWKKDQK  310

Query  298  PIVDEHEKQGFNGRFGPGTPRTSDGQFLFLLNLLSKMKPVTAENPQGSRLAIIMNGSPLF  357
            ++  EHE   + GRFG G PR SDGQ+LF LN +SK+K       + +R+AII NGS+LF
Sbjct  311  AVKAEHELGEL-GRFGVGLPRVSDGQLLFQLNGISKLK-------ETGRMAIIHNGSALF  362

Query  358  TGDAGSGESEIRKYVLENDLVEGIVALPNDLFYNTGIATYIWILTNNKAPLRKGKVELVN  417
            +G++G+GES IR+YV+END +EGI+ LPNDLFYNTGI+TYIWI+T++K+P R+GKV+LV+
Sbjct  363  SGNPGAGESLIRQYVIENDWLEGIIQLPNDLFYNTGISTYIWIITKDKSPERQGKVQLVD  422

Query  418  AVDFYKKMKKSMGSKRNEITEEQINNIVSLYGDFQEGEY--------VKIFDNEDFGYAK  469
            A + Y K +K++G KR +I+E   + IV  YG+F++ EY         KI+ NE FG+++
Sbjct  423  ASNMYEKRRKNIGEKRVDISEACREMIVQAYGEFNDKEYYLGDGTVESKILKNESFGFTR  482

Query  470  ITVERPLR  477
            +T+ERP R
Sbjct  483  VTIERPQR  490


 Score = 93.3 bits (335),  Expect = 5e-20, Method: Compositional matrix adjust.
 Identities = 62/170 (37%), Positives = 99/170 (59%), Gaps = 12/170 (7%)

Query  503  KKKGEAGLKEIEAGKELQTQIIKVLRNLASDEIYKNREAF-TKILK-DAFKEAEITVGAP  560
            K++ + G K ++ +   +  I++   ++   E Y    +  +KILK ++F  + +T+  P
Sbjct  429  KRRKNIGEKRVDISEACREMIVQAYGEFNDKEYYLGDGTVESKILKNESFGFTRVTIERP  488

Query  561  VLKAILNGLSEKDETADPCIKNKTEMEPDTDLRDTENVPLRESIHDYFEREVLPHVPDAW  620
                      ++DE +D   K++     DT+LRDTE++PL E I++YFERE+LP   DAW
Sbjct  489  ----------QRDENGDIVYKKNGSKSVDTNLRDTEDIPLTEDINEYFEREILPFNQDAW  538

Query  621  IDETKTKIGYEIPFTRQFYKYKALRGSQEIMEEIRVLEAEIAEQLEKVMG  670
            +D  K KIGYEIPFTR FYKY +   S+ I E I+ LE  I  +++ + G
Sbjct  539  MDRKKDKIGYEIPFTRLFYKYTPPEPSEVISERIKQLEESIIKNFQALSG  588

44) Clocl_0189 in NC_016627


> NC_002953_R1|4|G3|49484939|YP_042160.1|Staphylococcus_aureus_subsp._aureus_MSSA476|-|4742..6529|-|SAS0027|type 
I restriction 
enzyme methylase
Length=595

 Score =  377 bits (1419),  Expect = 1e-105, Method: Compositional matrix adjust.
 Identities = 231/489 (48%), Positives = 345/489 (71%), Gaps = 22/489 (4%)

Query  2    INFQDKVNFIWSIAELLRGPYKKEQYGDVILPMAVLRRFDCVLAATKQEVLEKYETLKKS  61
            IN Q + N+IW++A++LRG YK ++YG VILPM+V++R++  L  T++ VL   E  +  
Sbjct  12   INVQKQANLIWNVADILRGLYKPHEYGKVILPMTVIKRLHDTLLKTRDKVLKTAENTQSI  71

Query  62   GLQNMDPVLNRISKQEFNNTSKYDFEKLLADPDNIANNLRNYINGFSKNAREIIEHFDFD  121
                 + +L+  S   F NTS Y FE LLADP NI +N+R Y+NGFS N ++I+++F FD
Sbjct  72   NDVMRERLLKNASGYSFYNTSLYTFETLLADPANIESNFRAYLNGFSENMQDILNNFKFD  131

Query  122  KQITKLNDNNLLYLVVSEFNKID--LHPDVVSNTEMGYIFEELIRRFSE--HAEAGDHYT  177
             +IT + DN++L+ V+ EFNK D  L PD +++T+MGY+FEEL+R+FSE  + EAG H+T
Sbjct  132  VEITTMADNDVLFYVIQEFNKADAYLGPDKMTSTDMGYVFEELVRKFSESYNEEAGAHFT  191

Query  178  PREVIRLMVNILLNEDNEELTQPGLVVTVYDCCAGTGGMLSVAEQYLKELNPGIQVELFG  237
            +R++I LM ++LL ED++ L +  +  TVYD   GT+ MLS   + + ++N   +V  FG
Sbjct  192  SRDIIYLMTDLLLIEDKDTLFKEHVFKTVYDQTMGTSQMLSAMTERIHDMNDTAEVATFG  251

Query  238  QEINPQSFSICKSDMLIKGQNADNIILGDSFTEDGHRGRTFRYMLTNPPFGVEWKKAEKF  297
            QE+NP++++I K+D +I+G +++N+ LG ++T D   G TF Y ++NPPFGV+WKK +K 
Sbjct  252  QELNPETYAISKADTMIRGGDPENMALGSTLTSDRFEGFTFDYCISNPPFGVDWKKDQKA  311

Query  298  IREEYEKEGFNGRFGAGLPRISDGSLLFLQHLISKMKQDEKGSRIAIIFNGSPLFTGDAG  357
            ++ E E   + GRFG GLPR+SDG LLF  + ISK+K+    +R+AII NGS+LF+G++G
Sbjct  312  VKAEHELGEL-GRFGVGLPRVSDGQLLFQLNGISKLKE---TGRMAIIHNGSALFSGNPG  367

Query  358  SGESEIRRWIIENDMLEGIIALPDQLFYNTGISTYIWIVTNRKNSDPMKGPVRTGKIQLV  417
            +GES IR+ +IEND LEGII LP++LFYNTGISTYIWI+T+       K+P R GK+QLV
Sbjct  368  AGESLIRQYVIENDWLEGIIQLPNDLFYNTGISTYIWIITKD------KSPERQGKVQLV  421

Query  418  NAVDFYQKMRKSLGNKRNEITEEQIKEITRIYGEFKENEY--------CKIFDNEDFGYQ  469
            +A + Y+K RK++G+KR +I+E     I + YGEF+++EY         KI+ NE FG+ 
Sbjct  422  DASNMYEKRRKNIGEKRVDISEACREMIVQAYGEFNDKEYYLGDGTVESKILKNESFGFT  481

Query  470  KIVVERPLR  478
            ++ +ERP R
Sbjct  482  RVTIERPQR  490


 Score = 84.7 bits (302),  Expect = 2e-17, Method: Compositional matrix adjust.
 Identities = 47/78 (61%), Positives = 56/78 (72%), Gaps = 0/78 (0%)

Query  574  DETADICVDSKGNPEPDPDLRDTENVPLKEDIHEYFEREVKPHVPDAWIDETKTKIGYEI  633
            DE +DI    +G+   D +LRDTE++PL EDI+EYFERE+ P   DAW+D  K KIGYEI
Sbjct  491  DENGDIVYKKNGSKSVDTNLRDTEDIPLTEDINEYFEREILPFNQDAWMDRKKDKIGYEI  550

Query  634  PFTRHFYKYQPLRPSEEI  651
            PFTR FYKY P  PSE I
Sbjct  551  PFTRLFYKYTPPEPSEVI  568

45) CE0048 in NC_004369


> NC_002953_R1|4|G3|49484939|YP_042160.1|Staphylococcus_aureus_subsp._aureus_MSSA476|-|4742..6529|-|SAS0027|type 
I restriction 
enzyme methylase
Length=595

 Score =  376 bits (1414),  Expect = 3e-105, Method: Compositional matrix adjust.
 Identities = 234/485 (49%), Positives = 346/485 (72%), Gaps = 22/485 (4%)

Query  12   NHASFIWSAADLLRGTYKQHQYGNIILPFTVLARLDGVLAPTKQAVLTAIEGLDP-DQAP  70
            ++A++IW+ AD+LRG YK H+YG++ILP TV+ RL++ L  T++ VL + E  ++ ++  
Sbjct  16   KQANLIWNVADILRGLYKPHEYGKVILPMTVIKRLHDTLLKTRDKVLKTAENTQSINDVM  75

Query  71   SAGMLRNRAGHDYSFYNRSRHDLRSLQGDVDNLEENLRDYVNAFSPNVRDIFDQYKFDET  130
               +L+N +G  YSFYN S   + +L +D  N+E N+R Y+N+FS N++DI++++KFD  
Sbjct  76   RERLLKNASG--YSFYNTSLYTFETLLADPANIESNFRAYLNGFSENMQDILNNFKFDVE  133

Query  131  IIDLANNDLLLEILQHFAKAD--LRPEVVSNEVMGHIFEELIRKFAEASNETAGEHFTPR  188
            I  +A+ND+L+ ++Q+F KAD  L P+ +++  MG +FEEL+RKF+E+ NE AG HFT+R
Sbjct  134  ITTMADNDVLFYVIQEFNKADAYLGPDKMTSTDMGYVFEELVRKFSESYNEEAGAHFTSR  193

Query  189  EVIDLMVTILL-DGDEELSTPGVIRSVYDPTAGTGGMLSAADNKIKAFNHQAQVNLLGQE  247
            ++I LM  +LL ++ + L    V+++VYD T GT+ MLSA  ++I   N+ A+V  +GQE
Sbjct  194  DIIYLMTDLLLIEDKDTLFKEHVFKTVYDQTMGTSQMLSAMTERIHDMNDTAEVATFGQE  253

Query  248  INPESYAICKADMVVKGQPITNIALGNTLTNPAFEDQTFHYALSNPPFGVAWKKDRPAVE  307
            +NPE+YAI KAD +++G    N+ALG+TLT+  FE+ TF+Y +SNPPFGV WKKD+ AV 
Sbjct  254  LNPETYAISKADTMIRGGDPENMALGSTLTSDRFEGFTFDYCISNPPFGVDWKKDQKAVK  313

Query  308  REHEIAGHAGRFGPGLPRVSDGSLLFLMHLISKLREPGLQGGAAGRGAIVLNGSPLFTGG  367
             EHE+ G+ GRFG GLPRVSDG LLF ++ ISKL+E       +GR AI+ NGS+LF+G 
Sbjct  314  AEHEL-GELGRFGVGLPRVSDGQLLFQLNGISKLKE-------TGRMAIIHNGSALFSGN  365

Query  368  AGSGESNIRKWVLDNDYLEAIIGLPTDMFYNTGISTYIWILNKDKDHARKGKVQLIDATE  427
            +G+GES IR+ V++ND LE+II LP D+FYNTGISTYIWI+ KDK   R+GKVQL+DA++
Sbjct  366  PGAGESLIRQYVIENDWLEGIIQLPNDLFYNTGISTYIWIITKDKSPERQGKVQLVDASN  425

Query  428  MFVKMRKSIGSKRKMLSDDNITTIATLYGNFVESE--------HSKIFNTTDFYYRTITV  479
            M+ K RK+IG KR  +S+     I   YG+F + E        +SKI++   F +  +T+
Sbjct  426  MYEKRRKNIGEKRVDISEACREMIVQAYGEFNDKEYYLGDGTVESKILKNESFGFTRVTI  485

Query  480  ERPLK  484
            ERP +
Sbjct  486  ERPQR  490


 Score = 79.7 bits (283),  Expect = 6e-16, Method: Compositional matrix adjust.
 Identities = 41/93 (45%), Positives = 64/93 (69%), Gaps = 4/93 (4%)

Query  565  EHDDHGELV-TKAGKPEADASLRDTENVPWDQDIHDYLKREVHPFVPDAWIDETKTKEGV  623
            ++D++G++V  K G    D++LRDTE++P  +DI++Y+ RE+ PF  DAW+D  K K G 
Sbjct  489  QRDENGDIVYKKNGSKSVDTNLRDTEDIPLTEDINEYFEREILPFNQDAWMDRKKDKIGY  548

Query  624  EIPFTRHFYKYVPPRP---LKDIDRDLDEVLGR  653
            EIPFTR FYKY PP P   + +  ++L+E + +
Sbjct  549  EIPFTRLFYKYTPPEPSEVISERIKQLEESIIK  581

46) hsdM in NC_014549


> NC_002953_R1|4|G3|49484939|YP_042160.1|Staphylococcus_aureus_subsp._aureus_MSSA476|-|4742..6529|-|SAS0027|type 
I restriction 
enzyme methylase
Length=595

 Score =  375 bits (1409),  Expect = 6e-105, Method: Compositional matrix adjust.
 Identities = 227/486 (47%), Positives = 341/486 (71%), Gaps = 19/486 (3%)

Query  1    MSKHATFIWGIADLLRGNFKAHQYGDFILPFTVLRRLDSVLADTKSKVLEVVAEADAKGL  60
            + K+A +IW +AD+LRG +K+H+YG  ILP TV++RL+  L  T+ KVL    ++++   
Sbjct  14   VQKQANLIWNVADILRGLYKPHEYGKVILPMTVIKRLHDTLLKTRDKVLKTAENTQSIND  73

Query  61   SVRPVLLKTKAGHQHSFYNTSQYDLGTLIGDAENLRENLLSYINAFSENVRDIFVKYKIE  120
             +R  LLK  +G   SFYNTS Y + TL++D+ N+  N+ +Y+N+FSEN++DI+ ++K++
Sbjct  74   VMRERLLKNASGY--SFYNTSLYTFETLLADPANIESNFRAYLNGFSENMQDILNNFKFD  131

Query  121  DRIeeleennllllVIQRFAEVD--LHPKHVSNDKMGHIFEELIRKFAEASNETAGEHFT  178
              I  + +N++L+ VIQ F   D  L P  +++  MG +FEEL+RKF+E+ NE AG HFT
Sbjct  132  VEITTMADNDVLFYVIQEFNKADAYLGPDKMTSTDMGYVFEELVRKFSESYNEEAGAHFT  191

Query  179  PREVIELMVDLLFENDDEALRDEDIVRSVYDPTAGTGGMLSVAEDHLTAMNPRARLTLAG  238
            +R++I LM DLL+ +D ++L  E++ ++VYD T GT+ MLS   +++  MN  A ++  G
Sbjct  192  SRDIIYLMTDLLLIEDKDTLFKEHVFKTVYDQTMGTSQMLSAMTERIHDMNDTAEVATFG  251

Query  239  QELNPQSYAICKADMVIKGQSVDAIVNDDTLRHDGHAGTTFNYCLSNPPFGVDWKKQEKA  298
            QELNP++YAI KAD +I+G   + +  + TL  D   G TF+YC+SNPPFGVDWKK++KA
Sbjct  252  QELNPETYAISKADTMIRGGDPENMALGSTLTSDRFEGFTFDYCISNPPFGVDWKKDQKA  311

Query  299  VREEHAEKGFAGRFGPGLPRVSDGSMLFLLHLISKMREPAHGSAGGRAAIVLNGSPLFTG  358
            V+ EH E G  GRFG GLPRVSDG +LF L+ ISK++E       GR AI+ NGS+LF+G
Sbjct  312  VKAEH-ELGELGRFGVGLPRVSDGQLLFQLNGISKLKET------GRMAIIHNGSALFSG  364

Query  359  GAGSGESNIRKWILERDYLEAIIALPTDMFYNTGISTYIWVLSKEKSPERRNKVQLVDGS  418
             +G+GES IR+ ++E D LE+II LP D+FYNTGISTYIW+++K+KSPER+ KVQLVD+S
Sbjct  365  NPGAGESLIRQYVIENDWLEGIIQLPNDLFYNTGISTYIWIITKDKSPERQGKVQLVDAS  424

Query  419  KLFRKMRKGLGSKRNELGPEDIQAIVRLYGDFTETD--------QSKIFNTTDFFYRTIT  470
            +++ K RK +G KR +++    + IV+ YG+F + +        +SKI++   F +  +T
Sbjct  425  NMYEKRRKNIGEKRVDISEACREMIVQAYGEFNDKEYYLGDGTVESKILKNESFGFTRVT  484

Query  471  VERPLK  476
            +ERP +
Sbjct  485  IERPQR  490


 Score = 78.4 bits (278),  Expect = 1e-15, Method: Compositional matrix adjust.
 Identities = 41/83 (50%), Positives = 56/83 (68%), Gaps = 0/83 (0%)

Query  553  SKRDDTADVCTGPKSKIEPDAELRDTENVPWNEDIHAYIEREIKPFVPDAWLDEEKTKEG  612
            ++RD+ +D+    ++    D++LRDTE++P  EDI+ Y+EREI PF  DAW+D  K K G
Sbjct  488  PQRDENGDIVYKKNGSKSVDTNLRDTEDIPLTEDINEYFEREILPFNQDAWMDRKKDKIG  547

Query  613  CEIPFTRHFYQYIPPRPLEEIDA  635
             EIPFTR FY+Y PP P E I  
Sbjct  548  YEIPFTRLFYKYTPPEPSEVISE  570

47) C624_04845 in NC_021351


> NC_002953_R1|4|G3|49484939|YP_042160.1|Staphylococcus_aureus_subsp._aureus_MSSA476|-|4742..6529|-|SAS0027|type 
I restriction 
enzyme methylase
Length=595

 Score =  374 bits (1407),  Expect = 8e-105, Method: Compositional matrix adjust.
 Identities = 234/485 (49%), Positives = 343/485 (71%), Gaps = 22/485 (4%)

Query  3    NHASFIWSAADLLRGTYKQHQYGNIILPFTVLARLDGVLAPTKQAVLTAIEGLDP-DQAP  61
            ++A++IW+ AD+LRG YK H+YG++ILP TV+ RL++ L  T++ VL + E  ++ ++  
Sbjct  16   KQANLIWNVADILRGLYKPHEYGKVILPMTVIKRLHDTLLKTRDKVLKTAENTQSINDVM  75

Query  62   SAGMLRNRAGHDYSFYNRSRHDLASLQDDVDNLEDNLRDYVKAFSRNVRDIFDQYKFDET  121
               +L+N +G  YSFYN S   + +L  D  N+E N+R Y+++FS N++DI++++KFD  
Sbjct  76   RERLLKNASG--YSFYNTSLYTFETLLADPANIESNFRAYLNGFSENMQDILNNFKFDVE  133

Query  122  IIDLANNDLLLEILQHFAKAD--LRPEAVTNEVMGHIFEELIRKFAEASNETAGEHFTPR  179
            I  +A+ND+L+ ++Q+F KAD  L P+ +T+  MG +FEEL+RKF+E+ NE AG HFT+R
Sbjct  134  ITTMADNDVLFYVIQEFNKADAYLGPDKMTSTDMGYVFEELVRKFSESYNEEAGAHFTSR  193

Query  180  EVIDLMVTILL-DGDADLTTPGVIRSVYDPTAGTGGMLSAADNKIKHFNTHAQVNLLGQE  238
            ++I LM  +LL ++   L    V+++VYD T GT+ MLSA  ++I + N  A+V  +GQE
Sbjct  194  DIIYLMTDLLLIEDKDTLFKEHVFKTVYDQTMGTSQMLSAMTERIHDMNDTAEVATFGQE  253

Query  239  INPESYAICKADMVVKGQPITNIALGNTLTNQAFEDQTFHYALSNPPFGVAWKKDKPAVE  298
            +NPE+YAI KAD +++G    N+ALG+TLT++ FE+ TF+Y +SNPPFGV WKKD+ AV 
Sbjct  254  LNPETYAISKADTMIRGGDPENMALGSTLTSDRFEGFTFDYCISNPPFGVDWKKDQKAVK  313

Query  299  REHKFAGYSGRFGPGLPRVSDGSLLFLMHLISKLREPGLQGGAAGRGAIVLNGSPLFTGG  358
             EH ++   GRFG GLPRVSDG LLF ++ ISKL+E       +GR AI+ NGS+LF+G 
Sbjct  314  AEHELGE-LGRFGVGLPRVSDGQLLFQLNGISKLKE-------TGRMAIIHNGSALFSGN  365

Query  359  AGSGESNIRKWVLDNDYLEAIIGLPTDMFYNTGISTYIWILNKDKDPARKGKVQLIDATE  418
            +G+GES IR+ V++ND LE+II LP D+FYNTGISTYIWI+ KDK P R+GKVQL+DA++
Sbjct  366  PGAGESLIRQYVIENDWLEGIIQLPNDLFYNTGISTYIWIITKDKSPERQGKVQLVDASN  425

Query  419  MFVKMRKSIGSKRKMLSEDNIATIATLYGDFVESE--------HSKIFDVTDFYYRTITV  470
            M+ K RK+IG KR  +SE     I   YG+F + E        +SKI+    F +  +T+
Sbjct  426  MYEKRRKNIGEKRVDISEACREMIVQAYGEFNDKEYYLGDGTVESKILKNESFGFTRVTI  485

Query  471  ERPLK  475
            ERP +
Sbjct  486  ERPQR  490


 Score = 80.2 bits (285),  Expect = 4e-16, Method: Compositional matrix adjust.
 Identities = 41/94 (44%), Positives = 67/94 (72%), Gaps = 4/94 (4%)

Query  555  SEHDDHGELV-TRAGKPEADASLRDTENVPWDQDIHDYLEREVIPFVPDAWIDESKTKEG  613
            +++D++G++V  + G    D++LRDTE++P  +DI++Y+ERE++PF  DAW+D  K K G
Sbjct  488  PQRDENGDIVYKKNGSKSVDTNLRDTEDIPLTEDINEYFEREILPFNQDAWMDRKKDKIG  547

Query  614  VEIPFTRHFYQYVSPRPLEEID---RDLDEVLGR  644
             EIPFTR FY+Y +P P E I    ++L+E + +
Sbjct  548  YEIPFTRLFYKYTPPEPSEVISERIKQLEESIIK  581

48) C629_04845 in NC_021352


> NC_002953_R1|4|G3|49484939|YP_042160.1|Staphylococcus_aureus_subsp._aureus_MSSA476|-|4742..6529|-|SAS0027|type 
I restriction 
enzyme methylase
Length=595

 Score =  374 bits (1407),  Expect = 8e-105, Method: Compositional matrix adjust.
 Identities = 234/485 (49%), Positives = 343/485 (71%), Gaps = 22/485 (4%)

Query  3    NHASFIWSAADLLRGTYKQHQYGNIILPFTVLARLDGVLAPTKQAVLTAIEGLDP-DQAP  61
            ++A++IW+ AD+LRG YK H+YG++ILP TV+ RL++ L  T++ VL + E  ++ ++  
Sbjct  16   KQANLIWNVADILRGLYKPHEYGKVILPMTVIKRLHDTLLKTRDKVLKTAENTQSINDVM  75

Query  62   SAGMLRNRAGHDYSFYNRSRHDLASLQDDVDNLEDNLRDYVKAFSRNVRDIFDQYKFDET  121
               +L+N +G  YSFYN S   + +L  D  N+E N+R Y+++FS N++DI++++KFD  
Sbjct  76   RERLLKNASG--YSFYNTSLYTFETLLADPANIESNFRAYLNGFSENMQDILNNFKFDVE  133

Query  122  IIDLANNDLLLEILQHFAKAD--LRPEAVTNEVMGHIFEELIRKFAEASNETAGEHFTPR  179
            I  +A+ND+L+ ++Q+F KAD  L P+ +T+  MG +FEEL+RKF+E+ NE AG HFT+R
Sbjct  134  ITTMADNDVLFYVIQEFNKADAYLGPDKMTSTDMGYVFEELVRKFSESYNEEAGAHFTSR  193

Query  180  EVIDLMVTILL-DGDADLTTPGVIRSVYDPTAGTGGMLSAADNKIKHFNTHAQVNLLGQE  238
            ++I LM  +LL ++   L    V+++VYD T GT+ MLSA  ++I + N  A+V  +GQE
Sbjct  194  DIIYLMTDLLLIEDKDTLFKEHVFKTVYDQTMGTSQMLSAMTERIHDMNDTAEVATFGQE  253

Query  239  INPESYAICKADMVVKGQPITNIALGNTLTNQAFEDQTFHYALSNPPFGVAWKKDKPAVE  298
            +NPE+YAI KAD +++G    N+ALG+TLT++ FE+ TF+Y +SNPPFGV WKKD+ AV 
Sbjct  254  LNPETYAISKADTMIRGGDPENMALGSTLTSDRFEGFTFDYCISNPPFGVDWKKDQKAVK  313

Query  299  REHKFAGYSGRFGPGLPRVSDGSLLFLMHLISKLREPGLQGGAAGRGAIVLNGSPLFTGG  358
             EH ++   GRFG GLPRVSDG LLF ++ ISKL+E       +GR AI+ NGS+LF+G 
Sbjct  314  AEHELGE-LGRFGVGLPRVSDGQLLFQLNGISKLKE-------TGRMAIIHNGSALFSGN  365

Query  359  AGSGESNIRKWVLDNDYLEAIIGLPTDMFYNTGISTYIWILNKDKDPARKGKVQLIDATE  418
            +G+GES IR+ V++ND LE+II LP D+FYNTGISTYIWI+ KDK P R+GKVQL+DA++
Sbjct  366  PGAGESLIRQYVIENDWLEGIIQLPNDLFYNTGISTYIWIITKDKSPERQGKVQLVDASN  425

Query  419  MFVKMRKSIGSKRKMLSEDNIATIATLYGDFVESE--------HSKIFDVTDFYYRTITV  470
            M+ K RK+IG KR  +SE     I   YG+F + E        +SKI+    F +  +T+
Sbjct  426  MYEKRRKNIGEKRVDISEACREMIVQAYGEFNDKEYYLGDGTVESKILKNESFGFTRVTI  485

Query  471  ERPLK  475
            ERP +
Sbjct  486  ERPQR  490


 Score = 80.2 bits (285),  Expect = 4e-16, Method: Compositional matrix adjust.
 Identities = 41/94 (44%), Positives = 67/94 (72%), Gaps = 4/94 (4%)

Query  555  SEHDDHGELV-TRAGKPEADASLRDTENVPWDQDIHDYLEREVIPFVPDAWIDESKTKEG  613
            +++D++G++V  + G    D++LRDTE++P  +DI++Y+ERE++PF  DAW+D  K K G
Sbjct  488  PQRDENGDIVYKKNGSKSVDTNLRDTEDIPLTEDINEYFEREILPFNQDAWMDRKKDKIG  547

Query  614  VEIPFTRHFYQYVSPRPLEEID---RDLDEVLGR  644
             EIPFTR FY+Y +P P E I    ++L+E + +
Sbjct  548  YEIPFTRLFYKYTPPEPSEVISERIKQLEESIIK  581

49) BTG_16390 in NC_018500


> NC_002953_R1|4|G3|49484939|YP_042160.1|Staphylococcus_aureus_subsp._aureus_MSSA476|-|4742..6529|-|SAS0027|type 
I restriction 
enzyme methylase
Length=595

 Score =  374 bits (1407),  Expect = 8e-105, Method: Compositional matrix adjust.
 Identities = 233/487 (48%), Positives = 358/487 (74%), Gaps = 20/487 (4%)

Query  2    INFQDKVSFIWSIAEVLRGPYKPEDYGKVVLPLAVLRRFDCVLENTKDEVLANFEKFKAM  61
            IN Q + ++IW++A++LRG YKP++YGKV+LP++V++R++  L +T+D VL   E+ +++
Sbjct  12   INVQKQANLIWNVADILRGLYKPHEYGKVILPMTVIKRLHDTLLKTRDKVLKTAENTQSI  71

Query  62   NEDAREPILNRIAKQNFHNTSNYTFAKLLSDSDNIADNLRDYINGFSKTARDIMDHFDFD  121
            N+  RE +L+  +  +F NTS YTF  LL+D+ NI  N+R Y+NGFS   +DI+++F FD
Sbjct  72   NDVMRERLLKNASGYSFYNTSLYTFETLLADPANIESNFRAYLNGFSENMQDILNNFKFD  131

Query  122  RQIEKLDNNDLLYLTIKRFSELD--LHPEVVSNVEMGYIFEELIRRFSE--HAEAGDHYT  177
             +I  + +ND+L+  I+ F+  D  L P+ +++ +MGY+FEEL+R+FSE  + EAG H+T
Sbjct  132  VEITTMADNDVLFYVIQEFNKADAYLGPDKMTSTDMGYVFEELVRKFSESYNEEAGAHFT  191

Query  178  PREVVRLMVSLLFMQDDDILTKHGLTQTLYDCAAGTGGMGSVAQEYLTELNKTADLEFFA  237
            +R+++ LM  LL+++D D L K+ + +T+YD + GT+ M S   E + ++N TA++  F+
Sbjct  192  SRDIIYLMTDLLLIEDKDTLFKEHVFKTVYDQTMGTSQMLSAMTERIHDMNDTAEVATFG  251

Query  238  QEINGESYAICKADILIKGADAKNVRLGNTLSNDQFKGDKFDYLISNPPYGVDWKSYEKP  297
            QE+N E+YAI KAD +I+G+D+ N+ LG+TL++D+F G  FDY ISNPP+GVDWK  +K+
Sbjct  252  QELNPETYAISKADTMIRGGDPENMALGSTLTSDRFEGFTFDYCISNPPFGVDWKKDQKA  311

Query  298  IKAEHEEQGYAGRFGPGTPRTSDGQLLFLMHLISKMKPVTAENPQGSRLAIIMNGSPLFS  357
            +KAEH E G  GRFG G PR SDGQLLF ++ ISK+K       + +R+AII NGS+LFS
Sbjct  312  VKAEH-ELGELGRFGVGLPRVSDGQLLFQLNGISKLK-------ETGRMAIIHNGSALFS  363

Query  358  GDAGSGESEIRRYVLENDLVEGIVAMPNDLFYNTGIATYIWILTNNKAAIRKGKVQLVNA  417
            G++G+GES IR+YV+END +EGI+ +PNDLFYNTGI+TYIWI+T++K++ R+GKVQLV+A
Sbjct  364  GNPGAGESLIRQYVIENDWLEGIIQLPNDLFYNTGISTYIWIITKDKSPERQGKVQLVDA  423

Query  418  VDFskkmkksmgskRNEISQEQIDEIVRLYGNFTESE--------HVKIFDNEEFGYQKI  469
             +   K +K++G KR +IS+   + IV+ YG+F + E        + KI+ NE FG+ ++
Sbjct  424  SNMYEKRRKNIGEKRVDISEACREMIVQAYGEFNDKEYYLGDGTVESKILKNESFGFTRV  483

Query  470  TVERPLR  476
            T+ERP R
Sbjct  484  TIERPQR  490


 Score = 79.2 bits (281),  Expect = 9e-16, Method: Compositional matrix adjust.
 Identities = 43/81 (54%), Positives = 57/81 (71%), Gaps = 0/81 (0%)

Query  569  SEKDETADTCMKNKTDAEPNTDLRDTESVPLKEDMYEYFEREVKPHVSDAWIDESKTKIG  628
            +++DE +D   K++     +T+LRDTE +PL ED+ EYFERE+ P   DAW+D  K KIG
Sbjct  488  PQRDENGDIVYKKNGSKSVDTNLRDTEDIPLTEDINEYFEREILPFNQDAWMDRKKDKIG  547

Query  629  YEIPFTRQFYKYTKLRSSDEI  649
            YEIPFTR FYKYT   +S+ I
Sbjct  548  YEIPFTRLFYKYTPPEPSEVI  568

50) Nther_0795 in NC_010718


> NC_002953_R1|4|G3|49484939|YP_042160.1|Staphylococcus_aureus_subsp._aureus_MSSA476|-|4742..6529|-|SAS0027|type 
I restriction 
enzyme methylase
Length=595

 Score =  374 bits (1407),  Expect = 8e-105, Method: Compositional matrix adjust.
 Identities = 230/480 (48%), Positives = 350/480 (73%), Gaps = 14/480 (2%)

Query  7    QEKVNFIWSIADLLRGDYKRSDYGKVILPFTVLKRLDCALKPTKNKVLEEYKMLKDSGIQ  66
            Q + N+IW++AD+LRG YK  +YGKVILP TV+KRL+ +L  T++KVL      +     
Sbjct  15   QKQANLIWNVADILRGLYKPHEYGKVILPMTVIKRLHDTLLKTRDKVLKTAENTQSINDV  74

Query  67   NPEPVLNDITGQHFHNTSQFDFEKMKNEPDNIGDNLRHYINGFSTNARDIIEYFNFHDHL  126
              E +L++ +G  F NTS + FE +  +P NI  N+R Y+NGFS N +DI++ F+F+ ++
Sbjct  75   MRERLLKNASGYSFYNTSLYTFETLLADPANIESNFRAYLNGFSENMQDILNNFKFDVEI  134

Query  127  ERLEQSNLLYLIVSRFSEID--LSPEKVSNLEMGYIFEELIRKFSEQSNETAGEHFTPRE  184
              + ++++L+ ++  F+  D  L+P+K+++ +MGY+FEEL+RKFSE  NE AG HFT+R+
Sbjct  135  TTMADNDVLFYVIQEFNKADAYLGPDKMTSTDMGYVFEELVRKFSESYNEEAGAHFTSRD  194

Query  185  VIRLMVNLLFNEDSDLLQKEGLLRTIYDPACGTGGMLSVARDYLRELNNDAKLEMFGQEL  244
            +I LM +LL+ ED D L KE +++T+YD + GT+ MLS   + ++++N+ A +  FGQEL
Sbjct  195  IIYLMTDLLLIEDKDTLFKEHVFKTVYDQTMGTSQMLSAMTERIHDMNDTAEVATFGQEL  254

Query  245  NPESYAICKADMMIKGLDPDNIKFGNSFTNDGFSDNTFDYMLSNPPFGVEWkkiekeike  304
            NPE+YAI KAD MI+G DP+N+ +G+++T+D F + TFDY +SNPPFGV+WKK +K +K 
Sbjct  255  NPETYAISKADTMIRGGDPENMALGSTLTSDRFEGFTFDYCISNPPFGVDWKKDQKAVKA  314

Query  305  eHENLGFSGRYGAGLPRINDGSILFLQHMISKMQHQNGGSRIAIVLNGSPLFTGDAGQGE  364
            EHE LG  GR+G GLPR++DG +LF  + ISK+++    +R+AI+ NGS+LF+G++G GE
Sbjct  315  EHE-LGELGRFGVGLPRVSDGQLLFQLNGISKLKE---TGRMAIIHNGSALFSGNPGAGE  370

Query  365  SNIRKWIIENDLLEAIVALPEQLFYNTGINTYVWVLTNRKRPWRKGKIQLINAVEFYKKM  424
            S IR+ +IEND LE+I+ LP++LFYNTGI+TY+W++T+ K P R+GK+QL++A + Y K 
Sbjct  371  SLIRQYVIENDWLEGIIQLPNDLFYNTGISTYIWIITKDKSPERQGKVQLVDASNMYEKR  430

Query  425  RKSLGEKRHEISPEQIDKISKIYGEFKEGEY--------SKIFDNEDFGYYKITVERPLR  476
            RK++GEKR +IS    + I + YGEF++ EY        SKI+ NE FG+ ++T+ERP R
Sbjct  431  RKNIGEKRVDISEACREMIVQAYGEFNDKEYYLGDGTVESKILKNESFGFTRVTIERPQR  490


 Score = 89.1 bits (319),  Expect = 9e-19, Method: Compositional matrix adjust.
 Identities = 49/101 (49%), Positives = 69/101 (69%), Gaps = 0/101 (0%)

Query  570  EQDETAEICTDSKGNPEPDPDLRDNEIVSLKDDINGYFEREVKPHVPDAWIDESKTKIGY  629
            ++DE ++I    +G+   D +LRD E ++L +DIN YFERE+ P   DAW+D  K KIGY
Sbjct  489  QRDENGDIVYKKNGSKSVDTNLRDTEDIPLTEDINEYFEREILPFNQDAWMDRKKDKIGY  548

Query  630  EIPFTRHFYKYEPPREPEVIMEEIIELEHDIKEELKKVIGN  670
            EIPFTR FYKY PP  +EVI E I +LE+ I  +++ + G+
Sbjct  549  EIPFTRLFYKYTPPEPSEVISERIKQLEESIIKNFQALSGK  589

51) B841_03910 in NC_021915


> NC_002953_R1|4|G3|49484939|YP_042160.1|Staphylococcus_aureus_subsp._aureus_MSSA476|-|4742..6529|-|SAS0027|type 
I restriction 
enzyme methylase
Length=595

 Score =  370 bits (1390),  Expect = 2e-103, Method: Compositional matrix adjust.
 Identities = 230/485 (48%), Positives = 343/485 (71%), Gaps = 22/485 (4%)

Query  5    NHASFIWSAADLLRGTYKQHQYGNIILPFTVLARLDGVLAPTKQAVLAAIEGLDP-EQTP  63
            ++A++IW+ AD+LRG YK H+YG++ILP TV+ RL++ L  T++ VL + E  ++ ++  
Sbjct  16   KQANLIWNVADILRGLYKPHEYGKVILPMTVIKRLHDTLLKTRDKVLKTAENTQSINDVM  75

Query  64   SAGMLRNRAGHDYSFYNRSRHDLRSLQGDVDNLEENLRDYVNAFSPNVRDIFEQYKFDET  123
               +L+N +G  YSFYN S   + +L +D  N+E N+R Y+N+FS N++DI++++KFD  
Sbjct  76   RERLLKNASG--YSFYNTSLYTFETLLADPANIESNFRAYLNGFSENMQDILNNFKFDVE  133

Query  124  IIDLSNNDLLLEILQHFAKAD--LRPEAVSNEVMGHIFEELIRKFAEASNETAGEHFTPR  181
            I  +++ND+L+ ++Q+F KAD  L P+ +++  MG +FEEL+RKF+E+ NE AG HFT+R
Sbjct  134  ITTMADNDVLFYVIQEFNKADAYLGPDKMTSTDMGYVFEELVRKFSESYNEEAGAHFTSR  193

Query  182  EVIDLMVTILL-DGDADLTTPGVIRSVYDPTAGTGGMLSAADNKIKDFNEHAQVNLLGQE  240
            ++I LM  +LL ++   L    V+++VYD T GT+ MLSA  ++I D N+ A+V  +GQE
Sbjct  194  DIIYLMTDLLLIEDKDTLFKEHVFKTVYDQTMGTSQMLSAMTERIHDMNDTAEVATFGQE  253

Query  241  INPESYAICKADMVVKGQPITNIQLGNTLTNPAFEDQTFHYALSNPPFGVAWKKDRPAVE  300
            +NPE+YAI KAD +++G    N+ LG+TLT+  FE+ TF+Y +SNPPFGV WKKD+ AV 
Sbjct  254  LNPETYAISKADTMIRGGDPENMALGSTLTSDRFEGFTFDYCISNPPFGVDWKKDQKAVK  313

Query  301  REHKIAGYSGRFGPGLPRVSDGSLLFLMHLVSKLREPGLQGGAAGRGAIVLNGSPLFTGG  360
             EH ++   GRFG GLPRVSDG LLF ++ +SKL+E       +GR AI+ NGS+LF+G 
Sbjct  314  AEHELGE-LGRFGVGLPRVSDGQLLFQLNGISKLKE-------TGRMAIIHNGSALFSGN  365

Query  361  AGSGESNIRKWVLDNDYLEAIIGLPTDMFYNTGISTYVWILNKDKDPARKGKVQLIDATE  420
            +G+GES IR+ V++ND LE+II LP D+FYNTGISTY+WI+ KDK P R+GKVQL+DA++
Sbjct  366  PGAGESLIRQYVIENDWLEGIIQLPNDLFYNTGISTYIWIITKDKSPERQGKVQLVDASN  425

Query  421  MSVKMRKSIGSKRKLLSNDDITTITKLYGDFVESE--------HSKIFDTTDFYYRTITV  472
            M  K RK+IG KR  +S+     I + YG+F + E        +SKI+    F +  +T+
Sbjct  426  MYEKRRKNIGEKRVDISEACREMIVQAYGEFNDKEYYLGDGTVESKILKNESFGFTRVTI  485

Query  473  ERPLK  477
            ERP +
Sbjct  486  ERPQR  490


 Score = 81.0 bits (288),  Expect = 3e-16, Method: Compositional matrix adjust.
 Identities = 46/99 (47%), Positives = 67/99 (68%), Gaps = 4/99 (4%)

Query  552  VITELGEHDDHGELV-MKAGKPEADASLRDTENVPWDQDIHEYLEREVKPFVPDAWIDES  610
            V  E  ++D++G++V  K G    D++LRDTE++P  +DI+EY+ERE+ PF  DAW+D  
Sbjct  483  VTIERPQRDENGDIVYKKNGSKSVDTNLRDTEDIPLTEDINEYFEREILPFNQDAWMDRK  542

Query  611  KTKEGVEIPFTRHFYQYIPPRPLEDID---RDLDEVLGR  646
            K K G EIPFTR FY+Y PP P E I    ++L+E + +
Sbjct  543  KDKIGYEIPFTRLFYKYTPPEPSEVISERIKQLEESIIK  581

52) Turpa_0058 in NC_018020


> NC_002953_R1|4|G3|49484939|YP_042160.1|Staphylococcus_aureus_subsp._aureus_MSSA476|-|4742..6529|-|SAS0027|type 
I restriction 
enzyme methylase
Length=595

 Score =  369 bits (1386),  Expect = 4e-103, Method: Compositional matrix adjust.
 Identities = 219/488 (45%), Positives = 342/488 (71%), Gaps = 22/488 (4%)

Query  6    QEHIQFIWNIAEKLRGPYRPPQYRKVMIPMTVLRRLDCVLAPTKDKVLEQFKTLKGGKLQ  65
            Q + ++IWN+A+ LRG Y+P +Y KV++PMTV++RL+  L  T+DKVL      ++ +  
Sbjct  15   QKQANLIWNVADILRGLYKPHEYGKVILPMTVIKRLHDTLLKTRDKVLKTAENTQSINDV  74

Query  66   NIEPILQRVAGQKFYNTSKLDFEKLLGDPANIAANLVSYMTSFSPSALAILKHFNFEDEI  125
              E +L+  +G  FYNTS   FE LL+DPANI +N+ +Y+ +FS +   IL++F+F+ EI
Sbjct  75   MRERLLKNASGYSFYNTSLYTFETLLADPANIESNFRAYLNGFSENMQDILNNFKFDVEI  134

Query  126  EKLESANRLFMVVKDFAAID--LHPSRVSNIEMGYIFEELVRKFNEQANEEAGDHFTPRE  183
              +   + LF V+++F   D  L P ++++ +MGY+FEELVRKF+E  NEEAG HFT+R+
Sbjct  135  TTMADNDVLFYVIQEFNKADAYLGPDKMTSTDMGYVFEELVRKFSESYNEEAGAHFTSRD  194

Query  184  VIRLMVHLLFDPDDDTLTKKGIVRTIYDPACGTGGMLSIADEYIHEHNPQANLALFGQEY  243
            +I LM +LL+  D DTL K  + +T+YD + GT+ MLS   E IH+ N  A++A FGQE 
Sbjct  195  IIYLMTDLLLIEDKDTLFKEHVFKTVYDQTMGTSQMLSAMTERIHDMNDTAEVATFGQEL  254

Query  244  NSESYAVCGSDMLIKGEDVQNIAFGDTLGDGKTRDGHPDKKFHYMLSNPPFGVEWKPEEN  303
            N+E+YA+  +D +I+G D +N+A+G TL  ++  +G     F+Y +SNPPFGV+WK +++
Sbjct  255  NPETYAISKADTMIRGGDPENMALGSTLTSDRF-EGFT---FDYCISNPPFGVDWKKDQK  310

Query  304  VVRKEYETQGFNGRFGAGLPRISDGSFLFLQHMMSKFHKPPADGGDGSRLAIVFNGSPLF  363
             V+ E E   + GRFG GLPR+SDG +LF  + +SK+        + +R+AI+ NGS+LF
Sbjct  311  AVKAEHELGEL-GRFGVGLPRVSDGQLLFQLNGISKLK-------ETGRMAIIHNGSALF  362

Query  364  AGDAGSGESNIRKWIIENDWLEAIIALPDQMFYNTGIFTYLWVVTNRKVEARKGKVQLIN  423
            +G++G+GES IR+ +IENDWLE+II LP+++FYNTGI TY+W++T+ K   R+GKVQL++
Sbjct  363  SGNPGAGESLIRQYVIENDWLEGIIQLPNDLFYNTGISTYIWIITKDKSPERQGKVQLVD  422

Query  424  ATNLYQKMKKSLGNKRNELSAAHIDTIAKIYGEFAETE--------NSKTFRNQDFGYLK  475
            A+N+Y+K +K++G+KR ++S A  + I + YGEF + E        +SK ++N+ FG+ +
Sbjct  423  ASNMYEKRRKNIGEKRVDISEACREMIVQAYGEFNDKEYYLGDGTVESKILKNESFGFTR  482

Query  476  ITVERPLK  483
            +T+ERP +
Sbjct  483  VTIERPQR  490


 Score = 81.5 bits (290),  Expect = 2e-16, Method: Compositional matrix adjust.
 Identities = 47/117 (41%), Positives = 68/117 (59%), Gaps = 16/117 (13%)

Query  578  SERDETADICVDRHGKPEPDTDLRDTEIVPLPEASKLPIKDDDLPDFKVHCEDYLKREVL  637
            ++RDE +DI   ++G    DT+LRDTE +PL E                + ++Y+ RE+L
Sbjct  488  PQRDENGDIVYKKNGSKSVDTNLRDTEDIPLTE----------------DINEYFEREIL  531

Query  638  PHVPDAWIDHTKTKVGYEIPFNRYFYKYEPPRPLKEIESEIKAIEQEIMKMLSEVTT  694
            P   DAW+D+ K K+GYEIPF R FYKY PP P   I   IK +E+ I+K +  ++ 
Sbjct  532  PFNQDAWMDRKKDKIGYEIPFTRLFYKYTPPEPSEVISERIKQLEESIIKNFQALSG  588

53) DGI_1296 in NC_022444


> NC_002953_R1|4|G3|49484939|YP_042160.1|Staphylococcus_aureus_subsp._aureus_MSSA476|-|4742..6529|-|SAS0027|type 
I restriction 
enzyme methylase
Length=595

 Score =  367 bits (1378),  Expect = 2e-102, Method: Compositional matrix adjust.
 Identities = 215/484 (45%), Positives = 338/484 (70%), Gaps = 22/484 (4%)

Query  10   ASFIWSICNLLRGPYKRNEYRKVILPLTVLKRFDSVLAPTKAKALAAFETVKDKSENIVK  69
            A++IW++ ++LRG YK +EY KVILP+TV+KR++  L  T+ K L + E  +  ++ +  
Sbjct  18   ANLIWNVADILRGLYKPHEYGKVILPMTVIKRLHDTLLKTRDKVLKTAENTQSINDVMRE  77

Query  70   ATLCNVTGVEFYNISKLDFARLLDDPNNIALNLNSYISAFSPNVREIMERFKFGEQVAQM  129
              L N +G  FYN S   F  LL DP NI  N+ +Y+++FS N+++I++ FKF+ +++ M
Sbjct  78   RLLKNASGYSFYNTSLYTFETLLADPANIESNFRAYLNGFSENMQDILNNFKFDVEITTM  137

Query  130  QAKNLLYEVIKSFNTID--LSLQRVDNMQMGYVFEELIRIGAEQANEEAGEHFTPREVIK  187
              +++L+ VI+ FN  D  L+ +++ + +MGYVFEEL+R  +E  NEEAG HFT+R++I 
Sbjct  138  ADNDVLFYVIQEFNKADAYLGPDKMTSTDMGYVFEELVRKFSESYNEEAGAHFTSRDIIY  197

Query  188  LMVNLLLTDEGD-LTTSHIVKTIYDPACGTGGMLSTAESHIRALNQEASPHLFGQDWNDE  246
            LM +LLL ++ D L   H+ KT+YD + GT+ MLS+   +I+ +N+ A    FGQ+ N E
Sbjct  198  LMTDLLLIEDKDTLFKEHVFKTVYDQTMGTSQMLSAMTERIHDMNDTAEVATFGQELNPE  257

Query  247  SYAVCKADMLIKGENADNIRMGDIFTEDRFPHDTFDYMLANPPFGVSWKQQEKAIGKEHE  306
            +YA+ KAD +I+G +++N+ +G  +T DRF   TFDY ++NPPFGV WK+++KA+  EHE
Sbjct  258  TYAISKADTMIRGGDPENMALGSTLTSDRFEGFTFDYCISNPPFGVDWKKDQKAVKAEHE  317

Query  307  SRGYEGRFGAGLPRINDGALLFLQHMLSKMRRPEQGGSRIGIVFNGSPLFTGDAGSGESE  366
              G  GRFG GLPR++DG LLF  + +SK++      +R++I+ NGS+LF+G++G+GES 
Sbjct  318  L-GELGRFGVGLPRVSDGQLLFQLNGISKLK----ETGRMAIIHNGSALFSGNPGAGESL  372

Query  367  IRRWIIENDWLEAVVALPDQLFYNTGIFTYIWVLTNRKMPHRKGKIQLLDARSFFVKMRK  426
            IR+ +IENDWLE+++ LP++LFYNTGI TYIW++T+ K P+R+GK+QL+DA + + K RK
Sbjct  373  IRQYVIENDWLEGIIQLPNDLFYNTGISTYIWIITKDKSPERQGKVQLVDASNMYEKRRK  432

Query  427  SLGNKRNEIADGENGRPDQIAEIVRLYGAFRDGEC--------SRIFANEDFGYAKITVE  478
            ++G+KR +I+++          IV+ YG F D E         S+I+ NE FG++++T+E
Sbjct  433  NIGEKRVDISEACREM------IVQAYGEFNDKEYYLGDGTVESKILKNESFGFTRVTIE  486

Query  479  RPLR  482
            RP R
Sbjct  487  RPQR  490


 Score = 92.0 bits (330),  Expect = 1e-19, Method: Compositional matrix adjust.
 Identities = 48/92 (53%), Positives = 62/92 (68%), Gaps = 0/92 (0%)

Query  577  ERDEAAAICMDAKGAPEPDSSLRDTESVPLKESIQDYFRREVLPHVPDAWIDESKTRIGY  636
            +RDE + I    +G+   D++LRDTE +PL E I++YF RE+LP   DAW+D  K +IGY
Sbjct  489  QRDENGDIVYKKNGSKSVDTNLRDTEDIPLTEDINEYFEREILPFNQDAWMDRKKDKIGY  548

Query  637  EIPLTRHFYKYTPPRPLAEIEAEIKTLEREIM  668
            EIP+TR FYKYTPP P   I   IK LE  I+
Sbjct  549  EIPFTRLFYKYTPPEPSEVISERIKQLEESII  580

54) hsdM in NC_017771


> NC_002953_R1|4|G3|49484939|YP_042160.1|Staphylococcus_aureus_subsp._aureus_MSSA476|-|4742..6529|-|SAS0027|type 
I restriction 
enzyme methylase
Length=595

 Score =  365 bits (1372),  Expect = 5e-102, Method: Compositional matrix adjust.
 Identities = 212/477 (45%), Positives = 325/477 (69%), Gaps = 16/477 (3%)

Query  5    RMGNIIWATAELLRGDYKQADYGKVILPMTIARRLDGMAGRHRDDV-EAVLKEHGVTAA-  62
            + +N+IW  A++LRG YK  +YGKVILPMT+ +RL++   + RD V  +  + +++    
Sbjct  16   KQANLIWNVADILRGLYKPHEYGKVILPMTVIKRLHDTLLKTRDKVLKTAENTQSINDVM  75

Query  63   -PALLEHAAQGPVYNISGFTFEKLLADPGNLAANLIHFTSGFPESIREIFQRYKFAEKVQ  121
               LL +A+  + YN S +TFE LLADP+N+ +N+  + +GF+E++++I++ +KF   + 
Sbjct  76   RERLLKNASGYSFYNTSLYTFETLLADPANIESNFRAYLNGFSENMQDILNNFKFDVEIT  135

Query  122  DLADKDLLHQVVKKFASVDL----EHVSNEEMGNTFEDLIRRFSELSNETAGEHYTPREV  177
             +AD+D+L  V++ F   D     + +++ +MG  FE+L+R+FSE  NE AG H+T+R++
Sbjct  136  TMADNDVLFYVIQEFNKADAYLGPDKMTSTDMGYVFEELVRKFSESYNEEAGAHFTSRDI  195

Query  178  IHLMVQLLFTEDDDILATEGAIKKLYDPTAGTGGMLSSADDHVKGANPDAKLAVFGQELN  237
            I LM +LL+ ED D L  E  +K +YD T GT+ MLS+  +++ + N  A +A FGQELN
Sbjct  196  IYLMTDLLLIEDKDTLFKEHVFKTVYDQTMGTSQMLSAMTERIHDMNDTAEVATFGQELN  255

Query  238  DESYAICKADMVIKGYDPKNVQQGNTLTDDRHAGMKFDYVLSNPPFGVDWGKAFDAVAKE  297
             E+YAI KAD +I+G DP N+  G+TLT DR  G  FDY +SNPPFGVDW K  +   K 
Sbjct  256  PETYAISKADTMIRGGDPENMALGSTLTSDRFEGFTFDYCISNPPFGVDWKKD-QKAVKA  314

Query  298  RRTLGMTGRFGPGLPRKSDGTFLFMLHGLHKLDDGGRMAIVTNGSPLFTGNAGSGESEIR  357
             + LG  GRFG GLPR SDG +LF L+G+ KL + GRMAI+ NGS+LF+GN+G+GES IR
Sbjct  315  EHELGELGRFGVGLPRVSDGQLLFQLNGISKLKETGRMAIIHNGSALFSGNPGAGESLIR  374

Query  358  RHLLENDLVEAIIALPTDMFYNTGIQTYIWVLSKAKAEARKGKVQLIDAGKLFEKMPKSL  417
            + ++END +E+II LP D+FYNTGI TYIW+++K K+  R+GKVQL+DA++++EK  K++
Sbjct  375  QYVIENDWLEGIIQLPNDLFYNTGISTYIWIITKDKSPERQGKVQLVDASNMYEKRRKNI  434

Query  418  GSKRNRMSPEHIARVVKAHGDMEE--------SAISKVVPVAEFGYRTITVDRPMKH  466
            G KR  +S      +V+A G+ ++        +  SK++    FG+  +T++RP ++
Sbjct  435  GEKRVDISEACREMIVQAYGEFNDKEYYLGDGTVESKILKNESFGFTRVTIERPQRD  491


 Score = 75.7 bits (268),  Expect = 1e-14, Method: Compositional matrix adjust.
 Identities = 46/111 (42%), Positives = 71/111 (64%), Gaps = 12/111 (10%)

Query  538  AERDETAEPA--RDGKKRLLPDTDLRDTEDVPLTEDVQTYFEREVLAQAPDAWINDEVRD  595
            ++RDE ++    ++G K +  DT+LRDTED+PLTED++ YFERE+L+   DAW++   R 
Sbjct  488  PQRDENGDIVYKKNGSKSV--DTNLRDTEDIPLTEDINEYFEREILPFNQDAWMD---RK  542

Query  596  EKDGGLGKVGYEIPFNRYFYTYEAPPSLEKVDARIRARSSRIMDLLKAVVG  646
                  +K+GYEIPF R FY Y +P + E +  RI+     I+  ++A+ G
Sbjct  543  K-----DKIGYEIPFTRLFYKYTPPEPSEVISERIKQLEESIIKNFQALSG  588

55) NIES39_A06670 in NC_016640


> NC_002953_R1|4|G3|49484939|YP_042160.1|Staphylococcus_aureus_subsp._aureus_MSSA476|-|4742..6529|-|SAS0027|type 
I restriction 
enzyme methylase
Length=595

 Score =  365 bits (1371),  Expect = 6e-102, Method: Compositional matrix adjust.
 Identities = 220/511 (44%), Positives = 353/511 (70%), Gaps = 28/511 (5%)

Query  5    QNTTVDHQQLSNFIWQIADLLRGPYRPPQYERVMLPMTVLRRFDCILAPTKQDVLDKYQQ  64
            Q+T+++ Q+ +N+IW++AD+LRG Y+P +Y +V+LPMTV++R++  L  T++ VL K  +
Sbjct  8    QQTSINVQKQANLIWNVADILRGLYKPHEYGKVILPMTVIKRLHDTLLKTRDKVL-KTAE  66

Query  65   CKDRFKDEALDSMLNKAAGPDFRFHNRSEFTFEKLKGDPNNIDKHLVTYINSFSKNIREI  124
              + ++D   + +L++A+G  + F N S +TFE L +DP NI+ ++ +Y+N+FS N+++I
Sbjct  67   NTQSINDVMRERLLKNASG--YSFYNTSLYTFETLLADPANIESNFRAYLNGFSENMQDI  124

Query  125  FERFEFTAEIEKMNEANILYLVVSKF--CDVNLHPNQVDNIAMGSIFEDLIRRFNELANE  182
            ++ F F  EI  M + ++L+ V+  F   D  L P+++ +  MG +FE+L+R+F+E  NE
Sbjct  125  LNNFKFDVEITTMADNDVLFYVIQEFNKADAYLGPDKMTSTDMGYVFEELVRKFSESYNE  184

Query  183  TAGDHFTPREVIRLMVDILFDPDDDILTKPVICRLL-DPACGTGGMLSESQNYLRENNKE  241
             AG HFT+R++I LM D+L+  D D L K  + + + D + GT+ MLS   + +++ N  
Sbjct  185  EAGAHFTSRDIIYLMTDLLLIEDKDTLFKEHVFKTVYDQTMGTSQMLSAMTERIHDMNDT  244

Query  242  AQLWVFGQDFNPRAYAIAASDLLIKGNEQSAIQFGDSLTDDQYSGETFDYFLANPPFGVD  301
            A++  FGQ++NP +YAI+ +D +I+G +   + +G +LT D++ G TFDY ++NPPFGVD
Sbjct  245  AEVATFGQELNPETYAISKADTMIRGGDPENMALGSTLTSDRFEGFTFDYCISNPPFGVD  304

Query  302  WKKQQKDVKREHEKFGFAGRFGAGLPRVNDGSLLFLQHQISKFEPYQPDSDKKGSRLAIV  361
            WKK+QK VK EHE +G  GRFG GLPRV+DG LLF  + ISK+        K  +R+AI+
Sbjct  305  WKKDQKAVKAEHE-LGELGRFGVGLPRVSDGQLLFQLNGISKL--------KETGRMAII  355

Query  362  FNGSPLFTGGAGSGESEIRKWIIENDWLEAIVALPEQMFYNTGIGTYIWIVTNRKQKHRQ  421
             NGS+LF+G +G+GES IR+ +IENDWLE+I+ LP+++FYNTGI+TYIWI+T+ K  +RQ
Sbjct  356  HNGSALFSGNPGAGESLIRQYVIENDWLEGIIQLPNDLFYNTGISTYIWIITKDKSPERQ  415

Query  422  GKIQLIDARHRWQPMRRSLGDKRRYMGEEDIAIVVQEYGNFVETE--------TSKIFKN  473
            GK+QL+DA +  +  R+++G+KR  ++E    ++VQ YG+F + E         SKI+KN
Sbjct  416  GKVQLVDASNMYEKRRKNIGEKRVDISEACREMIVQAYGEFNDKEYYLGDGTVESKILKN  475

Query  474  EDFGYNRVPIERPLR-----LLYQMDTDRKL  499
            E FG+ RV IERP R     ++Y+ +  + +
Sbjct  476  ESFGFTRVTIERPQRDENGDIVYKKNGSKSV  506


 Score = 66.8 bits (234),  Expect = 5e-12, Method: Compositional matrix adjust.
 Identities = 36/82 (44%), Positives = 53/82 (65%), Gaps = 0/82 (0%)

Query  600  DSKLRDFENVNLQDEVTRYFLEEVEPHVSDAWADGAKIRSAFEINFNRYFYKYTPPRPLA  659
            D++LRD E++ L +++  YF  E+ P   DAW D  K + ++EI F R FYKYTPP P  
Sbjct  507  DTNLRDTEDIPLTEDINEYFEREILPFNQDAWMDRKKDKIGYEIPFTRLFYKYTPPEPSE  566

Query  660  EIDSDIKQMEEEIIKLLREVTA  681
             I   IKQ+EE IIK ++ +++
Sbjct  567  VISERIKQLEESIIKNFQALSG  588

56) RBAU_0694 in NC_022075


> NC_002953_R1|4|G3|49484939|YP_042160.1|Staphylococcus_aureus_subsp._aureus_MSSA476|-|4742..6529|-|SAS0027|type 
I restriction 
enzyme methylase
Length=595

 Score =  363 bits (1364),  Expect = 2e-101, Method: Compositional matrix adjust.
 Identities = 234/488 (48%), Positives = 356/488 (73%), Gaps = 21/488 (4%)

Query  2    INFQDKVSFIWSIAEILRGPYKPEDYGEIILPLAVLRRFDCVLESTREEVLVKAEQYPNM  61
            IN Q + ++IW++A+ILRG YKP++YG +ILP++V++R++  L  TR+ VL  AE+  ++
Sbjct  12   INVQKQANLIWNVADILRGLYKPHEYGKVILPMTVIKRLHDTLLKTRDKVLKTAENTQSI  71

Query  62   TDEAREQILNRVSKQNFHNISKYDFNKLLTDADNIADNLRDYINGFSKVARDIMEHFDFD  121
             D  RE++L+  S  +F N S Y F+ LL+D+ NI  N+R Y+NGFS   +DI+++F FD
Sbjct  72   NDVMRERLLKNASGYSFYNTSLYTFETLLADPANIESNFRAYLNGFSENMQDILNNFKFD  131

Query  122  RQIDKLDQNDLLYLTIKRFSEID--LHPETVSNIEMGYVFEELIRRFNE-YA-EAGDHYT  177
             +I  + +ND+L+  I+ F+  D  L P+ +++ +MGYVFEEL+R+F+E Y  EAG H+T
Sbjct  132  VEITTMADNDVLFYVIQEFNKADAYLGPDKMTSTDMGYVFEELVRKFSESYNEEAGAHFT  191

Query  178  PREVIRLMTHLLFLHDDASILTKPGLTQTLYDCAAGTGGMGSVAQEYLLNQNPTAHLEFF  237
            +R++I LMT+LL+++D  +++ K  + +T+YD + GT+ M S   E + + N TA++  F
Sbjct  192  SRDIIYLMTDLLLIEDKDTLF-KEHVFKTVYDQTMGTSQMLSAMTERIHDMNDTAEVATF  250

Query  238  GQEINPESYAICKADLLIKGEDARNIRLGNTLSNDQFPHDTFDYLISNPPYGVDWKSYEK  297
            GQE+NPE+YAI KAD +I+G D+ N+ LG+TL++D+F   TFDY ISNPP+GVDWK  +K
Sbjct  251  GQELNPETYAISKADTMIRGGDPENMALGSTLTSDRFEGFTFDYCISNPPFGVDWKKDQK  310

Query  298  AIKNEHEKQGFDGRFGPGTPRTSDGQLLFLMHLISKMKPVTVENPQGSRLAIIMNGSPLF  357
            A+K EHE   + GRFG G PR SDGQLLF ++ ISK+K       + +R+AII NGS+LF
Sbjct  311  AVKAEHELGEL-GRFGVGLPRVSDGQLLFQLNGISKLK-------ETGRMAIIHNGSALF  362

Query  358  TGDAGSGESEIRKYVLENDLVEGIVALPNDLFYNTGIATYIWILTNNKAPLHKGKVRLVN  417
            +G++G+GES IR+YV+END +EGI+ LPNDLFYNTGI+TYIWI+T++K+P ++GKV+LV+
Sbjct  363  SGNPGAGESLIRQYVIENDWLEGIIQLPNDLFYNTGISTYIWIITKDKSPERQGKVQLVD  422

Query  418  AVDFskkmkksmgskRNEITEEQINEIVRLYGDAQPNEY--------VKIFDNEDFGYAK  469
            A +   K +K++G KR +I+E   + IV+ YG+ + +EY         KI+ NE FG+++
Sbjct  423  ASNMYEKRRKNIGEKRVDISEACREMIVQAYGEFNDKEYYLGDGTVESKILKNESFGFTR  482

Query  470  ITVERPLR  477
            +T+ERP R
Sbjct  483  VTIERPQR  490


 Score = 90.7 bits (325),  Expect = 3e-19, Method: Compositional matrix adjust.
 Identities = 48/101 (48%), Positives = 70/101 (70%), Gaps = 0/101 (0%)

Query  570  SKKDETADVCMKNKTDIEPDTDLRDTENVPLKENIYDYFAREVLPHVPDAWIDESKTKIG  629
            +++DE +D+  K++     DT+LRDTE++PL E+I +YF RE+LP   DAW+D  K KIG
Sbjct  488  PQRDENGDIVYKKNGSKSVDTNLRDTEDIPLTEDINEYFEREILPFNQDAWMDRKKDKIG  547

Query  630  YEIPFTRHFYKYTALRSSAEIMDEIRALEAEIAEQLKKVIG  670
            YEIPFTR FYKYT+  +S  I + I+ LE  I  +++ + G
Sbjct  548  YEIPFTRLFYKYTPPEPSEVISERIKQLEESIIKNFQALSG  588

57) Oscil6304_1092 in NC_019693


> NC_002953_R1|4|G3|49484939|YP_042160.1|Staphylococcus_aureus_subsp._aureus_MSSA476|-|4742..6529|-|SAS0027|type 
I restriction 
enzyme methylase
Length=595

 Score =  363 bits (1365),  Expect = 2e-101, Method: Compositional matrix adjust.
 Identities = 217/511 (43%), Positives = 352/511 (69%), Gaps = 26/511 (5%)

Query  3    QPKNTTVDDQQLSNFIWQIADLLRGPYRPPQYERVMLPMTVLRRFDCILAPTKQDVLDKY  62
            + ++T+++ Q+ +N+IW++AD+LRG Y+P +Y +V+LPMTV++R++  L  T++ VL K 
Sbjct  6    RHQQTSINVQKQANLIWNVADILRGLYKPHEYGKVILPMTVIKRLHDTLLKTRDKVL-KT  64

Query  63   QQCKDRFKDDALDSMLNKAAGQRFHNRSEFTFEKLKGDPNNIDKHLVTYINSFSKNIREI  122
             +  + ++D   + +L++A+G  F N S +TFE L +DP NI+ ++ +Y+N+FS N+++I
Sbjct  65   AENTQSINDVMRERLLKNASGYSFYNTSLYTFETLLADPANIESNFRAYLNGFSENMQDI  124

Query  123  FERFEFTAEIEKMNEANILYLVVSKFCDVD--LHPNQVDNIAMGSIFEDLIRRFNELANE  180
            ++ F F  EI  M + ++L+ V+  F   D  L P+++ +  MG +FE+L+R+F+E  NE
Sbjct  125  LNNFKFDVEITTMADNDVLFYVIQEFNKADAYLGPDKMTSTDMGYVFEELVRKFSESYNE  184

Query  181  TAGDHFTPREVIRLMVDILFAPDDDILTKPVICRLL-DPACGTGGMLSESQNYLRENNKE  239
             AG HFT+R++I LM D+L+  D D L K  + + + D + GT+ MLS   + +++ N  
Sbjct  185  EAGAHFTSRDIIYLMTDLLLIEDKDTLFKEHVFKTVYDQTMGTSQMLSAMTERIHDMNDT  244

Query  240  AQLWVFGQDFNPRAYAIAASDLLIKGNEKSAIKFGDSLTDDQYSGETFDYFLANPPFGVD  299
            A++  FGQ++NP +YAI+ +D +I+G +   + +G +LT D++ G TFDY ++NPPFGVD
Sbjct  245  AEVATFGQELNPETYAISKADTMIRGGDPENMALGSTLTSDRFEGFTFDYCISNPPFGVD  304

Query  300  WKKQQKDVKREHEKFGFAGRFGAGLPRVNDGSLLFLQHQISKFEPYQPDSDKKGSRLVIV  359
            WKK+QK VK EHE +G  GRFG GLPRV+DG LLF  + ISK+        K  +R+ I+
Sbjct  305  WKKDQKAVKAEHE-LGELGRFGVGLPRVSDGQLLFQLNGISKL--------KETGRMAII  355

Query  360  FNGSPLFTGGAGSGESEIRKWIIESDWLEAIVALPEQMFYNTGIGTYIWIVTNRKQKHRQ  419
             NGS+LF+G +G+GES IR+ +IE+DWLE+I+ LP+++FYNTGI+TYIWI+T+ K  +RQ
Sbjct  356  HNGSALFSGNPGAGESLIRQYVIENDWLEGIIQLPNDLFYNTGISTYIWIITKDKSPERQ  415

Query  420  GKIQLIDARHRWQPMRRSLGDKRRYMGEEDIAIVVQEYGNFVETE--------TSKIFKN  471
            GK+QL+DA +  +  R+++G+KR  ++E    ++VQ YG+F + E         SKI+KN
Sbjct  416  GKVQLVDASNMYEKRRKNIGEKRVDISEACREMIVQAYGEFNDKEYYLGDGTVESKILKN  475

Query  472  EDFGYNRVPIERPLR-----LLYQMDTDRKL  497
            E FG+ RV IERP R     ++Y+ +  + +
Sbjct  476  ESFGFTRVTIERPQRDENGDIVYKKNGSKSV  506


 Score = 65.5 bits (229),  Expect = 1e-11, Method: Compositional matrix adjust.
 Identities = 35/83 (43%), Positives = 53/83 (64%), Gaps = 0/83 (0%)

Query  597  ADSKLRDFENVNLQHELTRYFLEEVEPHVSDAWADGDKIRSAFEINFNRYFYKYTPPRPL  656
             D++LRD E++ L +++  YF  E+ P   DAW D  K + ++EI F R FYKYTPP P 
Sbjct  506  VDTNLRDTEDIPLTEDINEYFEREILPFNQDAWMDRKKDKIGYEIPFTRLFYKYTPPEPS  565

Query  657  AEIDADIKQMEQEIIKLLREVTA  679
              I   IKQ+E+ IIK ++ +++
Sbjct  566  EVISERIKQLEESIIKNFQALSG  588

58) Amir_0960 in NC_013093


> NC_002953_R1|4|G3|49484939|YP_042160.1|Staphylococcus_aureus_subsp._aureus_MSSA476|-|4742..6529|-|SAS0027|type 
I restriction 
enzyme methylase
Length=595

 Score =  363 bits (1363),  Expect = 3e-101, Method: Compositional matrix adjust.
 Identities = 239/573 (42%), Positives = 366/573 (64%), Gaps = 35/573 (6%)

Query  1    MNSSKHTELANHAWSVADLLRGDYKQSDYGKVILPFTVLRRLECVLTPTKDKVLETAERF  60
            +N  K+++L    W+VAD+LRG YK  +YGKVILP TV++RL+  L  T+DKVL TAE  
Sbjct  12   INVQKQANLI---WNVADILRGLYKPHEYGKVILPMTVIKRLHDTLLKTRDKVLKTAENT  68

Query  61   AD-REMDPDRFLRKASGHSFYNTSTYTLKAIAGDATHAAKYLNEYLGAFSPNAREVLERY  119
                ++  +R+L++ASG SFYNTS YT+ ++ +D+++    +  YL +FS N +++L+ +
Sbjct  69   QSINDVMRERLLKNASGYSFYNTSLYTFETLLADPANIESNFRAYLNGFSENMQDILNNF  128

Query  120  EFAQQVKKLDAADLLYQVLGRFADLD--LRPEVVTNHQMGYIFEELIRRFAEQSNETAGE  177
             F  ++  +   D+L+ V+  F   D  L P+ +T+ +MGY+FEEL+R+F+E  NE AG 
Sbjct  129  KFDVEITTMADNDVLFYVIQEFNKADAYLGPDKMTSTDMGYVFEELVRKFSESYNEEAGA  188

Query  178  HFTPREVIDLMVKLLIAPDSDVLSVPGAVRTVLDPACGTGGMLSAAEEEITKHNKDATVK  237
            HFT+R++I LM  LL+  D D L      +TV D + GT+ MLSA  E I   N  A V 
Sbjct  189  HFTSRDIIYLMTDLLLIEDKDTLFKEHVFKTVYDQTMGTSQMLSAMTERIHDMNDTAEVA  248

Query  238  VFGQELNPESWAICRSDMMIKGQDPENIKFGNSFSDDSHAHATFDYVLANPPFGVDWKKV  297
             FGQELNPE+ AI ++D MI+G DPEN+ +G++++ D     TFDY ++NPPFGVDWKK 
Sbjct  249  TFGQELNPETYAISKADTMIRGGDPENMALGSTLTSDRFEGFTFDYCISNPPFGVDWKKD  308

Query  298  QETVEREHKMLGESGRFGAGLPRINDGSLLFLQHMISKMKPVDVDGKGGSRVAIVFNGSP  357
            Q +V  EH  LGE GRFG GLPR++DG LLF  + ISK+       K  +R+AI+ NGS+
Sbjct  309  QKAVKAEHE-LGELGRFGVGLPRVSDGQLLFQLNGISKL-------KETGRMAIIHNGSA  360

Query  358  LFTGAADSGESKIRRWILENDWLEGIVALPDQLFYNTGIFTYFWIVSNRKSKGRQGKVVL  417
            LF+G +++GES IR+ ++ENDWLEGI+ LP++LFYNTGI TY+WI+++ KS  RQGKV L
Sbjct  361  LFSGNPGAGESLIRQYVIENDWLEGIIQLPNDLFYNTGISTYIWIITKDKSPERQGKVQL  420

Query  418  LDARDYWQKMRKSLGDKRKMINEQQISEITRLYTEALAILDAEKNDQMHDLRNKGRKIKL  477
            +DA +  +K RK++G+KR  I+E     I + Y E         ND+   L +     K+
Sbjct  421  VDASNMYEKRRKNIGEKRVDISEACREMIVQAYGEF--------NDKEYYLGDGTVESKI  472

Query  478  FRNEDFGYRRITVERPLKLRFKVTEETLFALRAAKPVQ---KTTDAEMFTAALRPLIGKS  534
            ++NE FG+ R+T+ERP +       + ++   ++K+V+   + T+   +T  +   + + 
Sbjct  473  LKNESFGFTRVTIERPQR---DENGDIVYKKNGSKSVDTNLRDTEDIPLTEDINEYFERE  529

Query  535  WLK-KTEAWLDMKDAIVAAGLLWPTGVPFAKVL  566
             L  + +AW+D K   ++        +PF++++
Sbjct  530  ILPFNQDAWMDRKKDKIG------YEIPFTRLF  556


 Score = 91.0 bits (326),  Expect = 3e-19, Method: Compositional matrix adjust.
 Identities = 52/118 (45%), Positives = 74/118 (63%), Gaps = 2/118 (1%)

Query  545  MKDAIVAAGLLWPTGVPFAKVLRDAVGVRDPEGEVQ-KIKGEPEPDSELRDYENVPLDED  603
            + D+ V + +L   +  F++V  +    RD +G++  K +G    D++LRD E++PL ED
Sbjct  463  LGDGTVESKILKNESFGFTRVTIER-PQRDENGDIVYKKNGSKSVDTNLRDTEDIPLTED  521

Query  604  VDEYLRREVLPHAPDAWIDRTKTKIGYEIPFTRHFYEYQPPRPLPEIDAELKSLEAEI  661
            ++EY+ RE+LP   DAW+DR K KIGYEIPFTR FY Y PP P   I   +K LE  I
Sbjct  522  INEYFEREILPFNQDAWMDRKKDKIGYEIPFTRLFYKYTPPEPSEVISERIKQLEESI  579

59) hsdM in NC_015576


> NC_002953_R1|4|G3|49484939|YP_042160.1|Staphylococcus_aureus_subsp._aureus_MSSA476|-|4742..6529|-|SAS0027|type 
I restriction 
enzyme methylase
Length=595

 Score =  362 bits (1361),  Expect = 4e-101, Method: Compositional matrix adjust.
 Identities = 215/476 (46%), Positives = 327/476 (69%), Gaps = 11/476 (2%)

Query  14   LIWKIADLLRGPYQPNQYGDVILPFTILRRLDCILEPTKDQVLAEYKKISATK-VDPDVL  72
            LIW++AD+LRG Y+P++YG VILP T+++RL+  L  T+D+VL    +  + + V  + L
Sbjct  20   LIWNVADILRGLYKPHEYGKVILPMTVIKRLHDTLLKTRDKVLKTAENTQSINDVMRERL  79

Query  73   LKAKFKLPFYNTSRWSFASLISDPEGVADNLIDYIEHFSPNVRDVFEGFGMLDEIANLAK  132
            LK     +FYNTS  +F +L++DP  +  N+  Y++ FS N++D+++ F    EI+ +A 
Sbjct  80   LKNASGYSFYNTSLYTFETLLADPANIESNFRAYLNGFSENMQDILNNFKFDVEITTMAD  139

Query  133  TDRLYLIVKEFAAVD--LHPDVVTQHDMGYVFEELIRKFADSNATQAGDHFTPREVIALM  190
             D L+ +++EF   D  L PD +T  DMGYVFEEL+RKF++S   +AG HFT+R++I LM
Sbjct  140  NDVLFYVIQEFNKADAYLGPDKMTSTDMGYVFEELVRKFSESYNEEAGAHFTSRDIIYLM  199

Query  191  VDILFLTEDDALTKPGTVRTIYDPAAGTGGMLSVAYDHLVAMNPMARPVLYGQDVNPRSY  250
             D+L++ + D+L K    +T+YD + GT+ MLS   +++  MN  A    +GQ++NP +Y
Sbjct  200  TDLLLIEDKDTLFKEHVFKTVYDQTMGTSQMLSAMTERIHDMNDTAEVATFGQELNPETY  259

Query  251  ALCKSDMIVKGQDVDNIYLGDTLTDDGHRTKTFDFLLSNPPFGVDWKTQQKTVTDEHEQR  310
            A+ K+D +++G D +N+ LG TLT D     TFD+ +SNPPFGVDWK +QK+V  EHE  
Sbjct  260  AISKADTMIRGGDPENMALGSTLTSDRFEGFTFDYCISNPPFGVDWKKDQKAVKAEHELG  319

Query  311  GFAGRFGPGLPRVSDGSMLFLLHLISKMQPVKGGEGGSRLAIVLNGSPLFTGGAGSGESN  370
             + GRFG GLPRVSDG +LF L+ ISK++        +R+AI+ NGS+LF+G +G+GES 
Sbjct  320  EL-GRFGVGLPRVSDGQLLFQLNGISKLK------ETGRMAIIHNGSALFSGNPGAGESL  372

Query  371  IRQWIIENDLLDAIIALPTDMFYNTGIATYIWILDNNKPTKRRGKVQLINAVEMYGKMRK  430
            IRQ +IEND L++II LP D+FYNTGI+TYIWI+ ++K+  R+GKVQL++A +MY K RK
Sbjct  373  IRQYVIENDWLEGIIQLPNDLFYNTGISTYIWIITKDKSPERQGKVQLVDASNMYEKRRK  432

Query  431  SLGSKRKELRPKDIERICHLYESYRN-EHATDEHPAHSKVFKGEEFGYSTITVERP  485
            ++G KR ++     E I + Y  + + E   ++   +SK++K E FG++ +T+ERP
Sbjct  433  NIGEKRVDISEACREMIVQAYGEFNDKEYYLGDGTVESKILKNESFGFTRVTIERP  488


 Score = 96.8 bits (348),  Expect = 5e-21, Method: Compositional matrix adjust.
 Identities = 50/91 (55%), Positives = 67/91 (74%), Gaps = 0/91 (0%)

Query  565  EHDDTATIVTDAKGNPEPDTALRDTENVPLTEDIEEYFAREVLPHVPDAWIDHQKTKIGY  624
            ++D+ + IV   +G+   DT LRDTE++PLTEDI+EYF RE+LP   DAW+D++K KIGY
Sbjct  489  QRDENGDIVYKKNGSKSVDTNLRDTEDIPLTEDINEYFEREILPFNQDAWMDRKKDKIGY  548

Query  625  EIPFTRHFYRYTPPRPLEDIQKDLRVLVDEI  655
            EIPFTR FY+YTPP P E I   ++ L + I
Sbjct  549  EIPFTRLFYKYTPPEPSEVISERIKQLEESI  579

60) Francci3_0192 in NC_007777


> NC_002953_R1|4|G3|49484939|YP_042160.1|Staphylococcus_aureus_subsp._aureus_MSSA476|-|4742..6529|-|SAS0027|type 
I restriction 
enzyme methylase
Length=595

 Score =  362 bits (1359),  Expect = 4e-101, Method: Compositional matrix adjust.
 Identities = 246/597 (42%), Positives = 392/597 (66%), Gaps = 39/597 (6%)

Query  5    GSFIWSIADQLRGPYRPNQYGNVILPLTILRRLDCILEPDRETV---RELARTFDNPNRL  61
            +++IW++AD LRG Y+P++YG+VILP+T+++RL+  L   R+ V    E ++++++  R 
Sbjct  18   ANLIWNVADILRGLYKPHEYGKVILPMTVIKRLHDTLLKTRDKVLKTAENTQSINDVMRE  77

Query  62   KIEVKKATGRPFYNTSNYGFSNlladadgladnladyldRFSADV-DVFEYFDFKKEILA  120
            ++ +K+A+G +FYNTS Y F  LLAD+  +  N+  YL+ FS ++ D+++ F F  EI +
Sbjct  78   RL-LKNASGYSFYNTSLYTFETLLADPANIESNFRAYLNGFSENMQDILNNFKFDVEITT  136

Query  121  LEKAGLLREIITSFKAID--LHPKVVSNADMGDAFEYIIRKFNEAANETSGDHYTPRDAI  178
            +   ++L  +I  F+  D  L P  ++++DMG  FE ++RKF+E+ NE +G H+T+RD I
Sbjct  137  MADNDVLFYVIQEFNKADAYLGPDKMTSTDMGYVFEELVRKFSESYNEEAGAHFTSRDII  196

Query  179  RLLVDLLFAEKEADLSEAGIVRTLYDPTAGTGGMLALAEEHLLAQNPDANLSLYGQEYNP  238
             L+ DLL+ E    L    + +T+YD T GT+ ML+   E++   N  A+++ +GQE NP
Sbjct  197  YLMTDLLLIEDKDTLFKEHVFKTVYDQTMGTSQMLSAMTERIHDMNDTAEVATFGQELNP  256

Query  239  QSYAICKSDLLAKGHDATNIAFGNTLTDDAFKGRKFDFCMSNPPYGVDWKQYAKKVTEER  298
            ++YAI K+D + +G D+ N+A+G+TLT D F G  FD+C+SNPP+GVDWK+  K V  E+
Sbjct  257  ETYAISKADTMIRGGDPENMALGSTLTSDRFEGFTFDYCISNPPFGVDWKKDQKAVKAEH  316

Query  299  DEAGPYGRFAPGLPATSDGQMLFLLHLAHKMRAPKDGGGRVGIIMNGSPLFNGAAGSGPS  358
             E G  GRF+ GLP  SDGQ+LF L+   K++      GR++II NGS+LF+G +G+G S
Sbjct  317  -ELGELGRFGVGLPRVSDGQLLFQLNGISKLKET----GRMAIIHNGSALFSGNPGAGES  371

Query  359  EIRRWLLENDLVEAIVALPTNMFFNTGIATYIWILDNTKHPDARGLVQIIDGTSFWTKMR  418
             IR+ ++END +E+I+ LP ++F+NTGI+TYIWI+ + K P+ +G VQ++D+++   K R
Sbjct  372  LIRQYVIENDWLEGIIQLPNDLFYNTGISTYIWIITKDKSPERQGKVQLVDASNMYEKRR  431

Query  419  KNLGSKGREISDTDREKVVSLYVDFLDADPDY--------SKVLSNDEFGYWTITVERPL  470
            KN+G K  +IS++ RE +V  Y +F   D +Y        SK+L N+ FG+  +T+ERP 
Sbjct  432  KNIGEKRVDISEACREMIVQAYGEF--NDKEYYLGDGTVESKILKNESFGFTRVTIERPQ  489

Query  471  LGEDGKPVVDRKGQRKPDPKKRDTENVPFTYGGSTAGRAGKLDVINAYFDAEVKPHVPDA  530
             +E+G  V  ++G +  D + RDTE++P+T            + IN YF+ E+ P   DA
Sbjct  490  RDENGDIVYKKNGSKSVDTNLRDTEDIPLT------------EDINEYFEREILPFNQDA  537

Query  531  WIDWAKVKTGYEIPFTRHFYRYVPPRP---LAEIDADLDKQIAKILDLL--REVEGD  582
            W+D+ K K GYEIPFTR FY+Y PP P   ++E   +L+  I K ++ L  +EV+ +
Sbjct  538  WMDRKKDKIGYEIPFTRLFYKYTPPEPSEVISERIKQLEESIIKNFQALSGKEVDTN  594

61) BSUW23_03425 in NC_014479


> NC_002953_R1|4|G3|49484939|YP_042160.1|Staphylococcus_aureus_subsp._aureus_MSSA476|-|4742..6529|-|SAS0027|type 
I restriction 
enzyme methylase
Length=595

 Score =  362 bits (1360),  Expect = 5e-101, Method: Compositional matrix adjust.
 Identities = 229/488 (47%), Positives = 356/488 (73%), Gaps = 21/488 (4%)

Query  2    INFQDKVSFIWSIAEILRGPYKPEDYGKIILPLAVLRRFDCVLESTKEEVLAKAEQFATM  61
            IN Q + ++IW++A+ILRG YKP++YGK+ILP++V++R++  L  T++ VL  AE+  ++
Sbjct  12   INVQKQANLIWNVADILRGLYKPHEYGKVILPMTVIKRLHDTLLKTRDKVLKTAENTQSI  71

Query  62   KEDAREQILNRVSKQNFHNTSKYDFNKLLTDSDNIADNLRDYINGFSKVARDIMDHFDFD  121
            ++  RE++L+  S  +F NTS Y F+ LL+D+ NI  N+R Y+NGFS   +DI+++F FD
Sbjct  72   NDVMRERLLKNASGYSFYNTSLYTFETLLADPANIESNFRAYLNGFSENMQDILNNFKFD  131

Query  122  RQIDKLEQNNLLYLTIKRFSEID--LHPETVSNIEMGYVFEELIRRFNE--NAEAGDHYT  177
             +I  + +N++L+  I+ F+  D  L P+ +++ +MGYVFEEL+R+F+E  N EAG H+T
Sbjct  132  VEITTMADNDVLFYVIQEFNKADAYLGPDKMTSTDMGYVFEELVRKFSESYNEEAGAHFT  191

Query  178  PREVIRLMTHLLFLHDDASILTKPGLTQTLYDCAAGTGGMGSVAQEYLLSQNPTAHLEFF  237
            +R++I LMT+LL+++D  +++ K  + +T+YD + GT+ M S   E +   N TA++  F
Sbjct  192  SRDIIYLMTDLLLIEDKDTLF-KEHVFKTVYDQTMGTSQMLSAMTERIHDMNDTAEVATF  250

Query  238  GQEINPESYAICKADLLIKGEDARNIRLGNTLSKDQFPRDKFDYLISNPPYGVDWKSYEK  297
            GQE+NPE+YAI KAD +I+G D+ N+ LG+TL+ D+F    FDY ISNPP+GVDWK  +K
Sbjct  251  GQELNPETYAISKADTMIRGGDPENMALGSTLTSDRFEGFTFDYCISNPPFGVDWKKDQK  310

Query  298  PIKEEHEKQGFNGRFGPGTPRTSDGQLLFLMHLLSKMKPVTAENPQGSRLAIIMNGSPLF  357
            ++K EHE   + GRFG G PR SDGQLLF ++ +SK+K       + +R+AII NGS+LF
Sbjct  311  AVKAEHELGEL-GRFGVGLPRVSDGQLLFQLNGISKLK-------ETGRMAIIHNGSALF  362

Query  358  TGDAGSGESEIRKYLLENDLVEGIVALPNDLFYNTGIATYIWILTNNKAPLHKGKVRLVN  417
            +G++G+GES IR+Y++END +EGI+ LPNDLFYNTGI+TYIWI+T++K+P ++GKV+LV+
Sbjct  363  SGNPGAGESLIRQYVIENDWLEGIIQLPNDLFYNTGISTYIWIITKDKSPERQGKVQLVD  422

Query  418  AVDFskkmkksmgskRNEITEEQINEIVRLYGDAQPNEY--------VKIFDNEDFGYAK  469
            A +   K +K++G KR +I+E   + IV+ YG+ + +EY         KI+ NE FG+++
Sbjct  423  ASNMYEKRRKNIGEKRVDISEACREMIVQAYGEFNDKEYYLGDGTVESKILKNESFGFTR  482

Query  470  ITVERPLR  477
            +T+ERP R
Sbjct  483  VTIERPQR  490


 Score = 93.6 bits (336),  Expect = 4e-20, Method: Compositional matrix adjust.
 Identities = 48/97 (50%), Positives = 70/97 (73%), Gaps = 0/97 (0%)

Query  570  SEKDETADICMKNKTDIEPDTDLRDTENVPLKENIHDYFAREVLPHVPDAWIDETKTKIG  629
            +++DE +DI  K++     DT+LRDTE++PL E+I++YF RE+LP   DAW+D  K KIG
Sbjct  488  PQRDENGDIVYKKNGSKSVDTNLRDTEDIPLTEDINEYFEREILPFNQDAWMDRKKDKIG  547

Query  630  YEIPFTRQFYKYTALRSSTEIMDEIRALEAEIVEQLK  666
            YEIPFTR FYKYT+  +S  I + I+ LE  I+ +++
Sbjct  548  YEIPFTRLFYKYTPPEPSEVISERIKQLEESIIKNFQ  584

62) I33_0764 in NC_017195


> NC_002953_R1|4|G3|49484939|YP_042160.1|Staphylococcus_aureus_subsp._aureus_MSSA476|-|4742..6529|-|SAS0027|type 
I restriction 
enzyme methylase
Length=595

 Score =  360 bits (1354),  Expect = 1e-100, Method: Compositional matrix adjust.
 Identities = 232/488 (48%), Positives = 355/488 (73%), Gaps = 21/488 (4%)

Query  2    INFQDKVNFIWSIAEILRGPYKPEDYGKIILPLAVLRRFDCVLESTKEEVLAKAEQFAAM  61
            IN Q + N+IW++A+ILRG YKP++YGK+ILP++V++R++  L  T++ VL  AE+  ++
Sbjct  12   INVQKQANLIWNVADILRGLYKPHEYGKVILPMTVIKRLHDTLLKTRDKVLKTAENTQSI  71

Query  62   NEDAREQILNRVSKQNFHNTSKYDFNKLLTDSDNIADNLRDYINGFSKVARDIMDQFDFD  121
            N+  RE++L+  S  +F NTS Y F+ LL+D+ NI  N+R Y+NGFS   +DI+++F FD
Sbjct  72   NDVMRERLLKNASGYSFYNTSLYTFETLLADPANIESNFRAYLNGFSENMQDILNNFKFD  131

Query  122  RQIDKLEQNNLLYLTIKRFSEID--LHPETVSNIEMGYVFEELIRRFNE--NAEAGDHYT  177
             +I  + +N++L+  I+ F+  D  L P+ +++ +MGYVFEEL+R+F+E  N EAG H+T
Sbjct  132  VEITTMADNDVLFYVIQEFNKADAYLGPDKMTSTDMGYVFEELVRKFSESYNEEAGAHFT  191

Query  178  PREVIRLMTHLLFLHDDASILTKPGLTQTLYDCAAGTGGMGSVAQEYLLSQNPTAHLEFF  237
            +R++I LMT+LL+++D  +++ K  + +T+YD + GT+ M S   E +   N TA++  F
Sbjct  192  SRDIIYLMTDLLLIEDKDTLF-KEHVFKTVYDQTMGTSQMLSAMTERIHDMNDTAEVATF  250

Query  238  GQEINPESYAICKADLLIKGEDARNIRLGNTLSKDQFPRDKFDYLISNPPYGVDWKSYEK  297
            GQE+NPE+YAI KAD +I+G D+ N+ LG+TL+ D+F    FDY ISNPP+GVDWK  +K
Sbjct  251  GQELNPETYAISKADTMIRGGDPENMALGSTLTSDRFEGFTFDYCISNPPFGVDWKKDQK  310

Query  298  PIKEEHEKQGFNGRFGPGTPRTSDGQLLFLMHLLSKMKPVTVENPQGSRLAIIMNGSPLF  357
            ++K EHE   + GRFG G PR SDGQLLF ++ +SK+K       + +R+AII NGS+LF
Sbjct  311  AVKAEHELGEL-GRFGVGLPRVSDGQLLFQLNGISKLK-------ETGRMAIIHNGSALF  362

Query  358  TGDAGSGESEIRKYVLENDLVEGIVALPNDLFYNTGIATYIWILTNNKAPLYKGKVRLVN  417
            +G++G+GES IR+YV+END +EGI+ LPNDLFYNTGI+TYIWI+T++K+P  +GKV+LV+
Sbjct  363  SGNPGAGESLIRQYVIENDWLEGIIQLPNDLFYNTGISTYIWIITKDKSPERQGKVQLVD  422

Query  418  AVDFskkmkksmgskRNEITEEQINEIVRLYGDAQPNEY--------VKIFDNEDFGYAK  469
            A +   K +K++G KR +I+E   + IV+ YG+ + +EY         KI+ NE FG+++
Sbjct  423  ASNMYEKRRKNIGEKRVDISEACREMIVQAYGEFNDKEYYLGDGTVESKILKNESFGFTR  482

Query  470  ITVERPLR  477
            +T+ERP R
Sbjct  483  VTIERPQR  490


 Score = 92.8 bits (333),  Expect = 6e-20, Method: Compositional matrix adjust.
 Identities = 47/101 (47%), Positives = 71/101 (71%), Gaps = 0/101 (0%)

Query  570  SEKDETADVCMKNKTDIEPDTDLRDTENVPLKENIHDYFAREVLPHVPDAWIDESKTKIG  629
            +++DE +D+  K++     DT+LRDTE++PL E+I++YF RE+LP   DAW+D  K KIG
Sbjct  488  PQRDENGDIVYKKNGSKSVDTNLRDTEDIPLTEDINEYFEREILPFNQDAWMDRKKDKIG  547

Query  630  YEIPFTRQFYKYSALRSSAEIMDEIRALEAEIAEQLKKVMG  670
            YEIPFTR FYKY++  +S  I + I+ LE  I  +++ + G
Sbjct  548  YEIPFTRLFYKYTPPEPSEVISERIKQLEESIIKNFQALSG  588

63) VAB18032_25315 in NC_015434


> NC_002953_R1|4|G3|49484939|YP_042160.1|Staphylococcus_aureus_subsp._aureus_MSSA476|-|4742..6529|-|SAS0027|type 
I restriction 
enzyme methylase
Length=595

 Score =  360 bits (1354),  Expect = 1e-100, Method: Compositional matrix adjust.
 Identities = 246/594 (42%), Positives = 390/594 (66%), Gaps = 37/594 (6%)

Query  5    GSFIWSIADQLRGPYRPNQYGNVILPLTILRRLDYILEPDRELVRALAAKYDNPNRLKIE  64
            +++IW++AD LRG Y+P++YG+VILP+T+++RL+  L   R+ V   A + ++ N +  E
Sbjct  18   ANLIWNVADILRGLYKPHEYGKVILPMTVIKRLHDTLLKTRDKVLKTAENTQSINDVMRE  77

Query  65   --VKKATGRPFYNTSNYSFanlladadgladnladYIDRFSPDV-DVFQYFDFkkeilal  121
              +K+A+G +FYNTS Y+F  LLAD+  +  N+  Y++ FS ++ D+++ F F  EI ++
Sbjct  78   RLLKNASGYSFYNTSLYTFETLLADPANIESNFRAYLNGFSENMQDILNNFKFDVEITTM  137

Query  122  ekaellreVITSFKAVN--LHPDVVSNADMGDAFEYIIRKFNEAANETSGDHYTPRDAIR  179
               ++L  VI  F+  +  L PD ++++DMG  FE ++RKF+E+ NE +G H+T+RD I 
Sbjct  138  ADNDVLFYVIQEFNKADAYLGPDKMTSTDMGYVFEELVRKFSESYNEEAGAHFTSRDIIY  197

Query  180  LLVDLLFAERDAELTEADIVRSLYDPTAGTGGMLALAEEHLLAQNPGAKLRLYGQEYNPQ  239
            L+ DLL+ E    L   ++ +++YD T GT+ ML+   E++   N  A +  +GQE NP+
Sbjct  198  LMTDLLLIEDKDTLFKEHVFKTVYDQTMGTSQMLSAMTERIHDMNDTAEVATFGQELNPE  257

Query  240  SYAICKSDLLAKGHDTTNIAFGNTLTDPAFKDRKFDFCMSNPPYGVDWKQYAKAVTKERD  299
            +YAI K+D + +G D  N+A+G+TLT   F +  FD+C+SNPP+GVDWK+  KAV  E+ 
Sbjct  258  TYAISKADTMIRGGDPENMALGSTLTSDRFEGFTFDYCISNPPFGVDWKKDQKAVKAEH-  316

Query  300  EAGPYGRFAPGLPATSDGQMLFLLHLVHKMRAPEDGGGRAGIVMNGSPLFNGAAESGPSN  359
            E G  GRF+ GLP  SDGQ+LF L+ + K++      GR +I+ NGS+LF+G + +G S 
Sbjct  317  ELGELGRFGVGLPRVSDGQLLFQLNGISKLKET----GRMAIIHNGSALFSGNPGAGESL  372

Query  360  IRKWLLEHDLVDAIVALPTNMFFNTGIATYIWILDNTKHPDRKGLVQLIDGTSFWTKMRK  419
            IR+ ++E+D +++I+ LP ++F+NTGI+TYIWI+ + K P+R+G VQL+D+++   K RK
Sbjct  373  IRQYVIENDWLEGIIQLPNDLFYNTGISTYIWIITKDKSPERQGKVQLVDASNMYEKRRK  432

Query  420  NLGAKNRELSEENRAKVVQLYADFTDGDPDY--------SKVLRNDEFGYWTITVERPLL  471
            N+G K  ++SE  R  +VQ Y++F   D +Y        SK+L+N+ FG+  +T+ERP  
Sbjct  433  NIGEKRVDISEACREMIVQAYGEFN--DKEYYLGDGTVESKILKNESFGFTRVTIERPQR  490

Query  472  DESGNPVVDRKGKPKPDTKKRDTENVPFTYGGSTAGAAGKIEVIQAYFDVEVKPHVPDAW  531
            DE+G+ V  ++G    DT+ RDTE++P+T            E I+ YF+ E+ P   DAW
Sbjct  491  DENGDIVYKKNGSKSVDTNLRDTEDIPLT------------EDINEYFEREILPFNQDAW  538

Query  532  IDWTKVKTGYEIPFTRHFYKYVPPRP---LAEIDADLEKQVAKILDLL--REVE  580
            +D+ K K GYEIPFTR FYKY PP P   ++E   +LE  + K ++ L  +EV+
Sbjct  539  MDRKKDKIGYEIPFTRLFYKYTPPEPSEVISERIKQLEESIIKNFQALSGKEVD  592

64) Maqu_0234 in NC_008740


> NC_002953_R1|4|G3|49484939|YP_042160.1|Staphylococcus_aureus_subsp._aureus_MSSA476|-|4742..6529|-|SAS0027|type 
I restriction 
enzyme methylase
Length=595

 Score =  359 bits (1349),  Expect = 3e-100, Method: Compositional matrix adjust.
 Identities = 211/476 (45%), Positives = 342/476 (72%), Gaps = 18/476 (3%)

Query  12   AAFIWSVADLLRGDFKQSQYGRVILPFTLLRRLECVLEPTKAQVLSAAQEHQAKPDAVRE  71
            A +IW+VAD+LRG +K  +YG+VILP T+++RL+  L  T+ +VL +A++ Q+  D +RE
Sbjct  18   ANLIWNVADILRGLYKPHEYGKVILPMTVIKRLHDTLLKTRDKVLKTAENTQSINDVMRE  77

Query  72   KLLLRAAGQQFFNASPLSLATL--SDSQTADDLMSYVQSFSQDAREIFEHFHFEDFVQQL  129
            +LL  A+G  F+N+S  ++ TL    ++   ++ +Y+++FS++ ++I+++F F+  +  +
Sbjct  78   RLLKNASGYSFYNTSLYTFETLLADPANIESNFRAYLNGFSENMQDILNNFKFDVEITTM  137

Query  130  SANNLLYQVVQRFASID--LSPATISNFGMGIIFEELIRKFAESSNETAGEHFTPRDIVH  187
            + N++L+ V+Q F   D  L+P  +++ +MG +FEEL+RKF+ES NE AG HFT+RDI+ 
Sbjct  138  ADNDVLFYVIQEFNKADAYLGPDKMTSTDMGYVFEELVRKFSESYNEEAGAHFTSRDIIY  197

Query  188  LTTSLVLTGQEGRLTPNSIV-TIYDPTAGTGGFLSEGDEYIQQISESVTVSLHGQELNPE  246
            L T L+L  + + L  + +  T+YD T GT+  LS   E I++++++  V+  GQELNPE
Sbjct  198  LMTDLLLIEDKDTLFKEHVFKTVYDQTMGTSQMLSAMTERIHDMNDTAEVATFGQELNPE  257

Query  247  SYAICKADMLIKGQEVSNIKLGNTLSDDQLATNKFDLMLSNPPFGVEWKKVQKQVTDEHK  306
            +YAI KAD +I+G +  N+ LG+TL+ D++    FD  +SNPPFGV+WKK QK V  EH 
Sbjct  258  TYAISKADTMIRGGDPENMALGSTLTSDRFEGFTFDYCISNPPFGVDWKKDQKAVKAEHE  317

Query  307  HRGFDGRFGPGLPRVSDGSLLFLMHLVSKMRDAREGGSRIGIILNGSPLFTGGAGSGESE  366
               + GRFG GLPRVSDG LLF ++ +SK++++    +R++II NGS+LF+G +G+GES 
Sbjct  318  LGEL-GRFGVGLPRVSDGQLLFQLNGISKLKET----GRMAIIHNGSALFSGNPGAGESL  372

Query  367  IRRYLLQNDMVEAIVALPTDMFYNTGISTYVWVLSNNKPAERRGKVQLIDATDRATKMRK  426
            IR+Y+++ND +E+I+ LP D+FYNTGISTY+W+++++K++ER+GKVQL+DA++   K RK
Sbjct  373  IRQYVIENDWLEGIIQLPNDLFYNTGISTYIWIITKDKSPERQGKVQLVDASNMYEKRRK  432

Query  427  SLGSKRQFVSESDQDEIVRMYGDFQE--------TKKSKIFPIEAFGYRRITVERP  474
            ++G KR  +SE+ ++ IV+ YG+F++        T  SKI+  E+FG+ R+T+ERP
Sbjct  433  NIGEKRVDISEACREMIVQAYGEFNDKEYYLGDGTVESKILKNESFGFTRVTIERP  488


 Score = 75.5 bits (267),  Expect = 1e-14, Method: Compositional matrix adjust.
 Identities = 49/165 (30%), Positives = 92/165 (56%), Gaps = 16/165 (9%)

Query  501  EDQGNIHAACRAMNAKT--VYRNRKQF--QKALKASLTDHQVYLGAPQLKSLLNALSERD  556
            E + +I  ACR M  ++   + ++  +  + ++ + +  ++ +     +  +    ++RD
Sbjct  436  EKRVDISEACREMIVQAYGEFNDKEYYLGDGTVESKILKNESF----GFTRVTIERPQRD  491

Query  557  PEADICTDSKGNPEADTGLRDYENVPLSESVYDYFVREVKPHVPDAWIDESKRDEKDGEV  616
             ++DI    +G+   DT LRD E++PL+E + +YF RE+ P   DAW+D  ++ +K    
Sbjct  492  ENGDIVYKKNGSKSVDTNLRDTEDIPLTEDINEYFEREILPFNQDAWMD--RKKDK----  545

Query  617  GIVGFEIPFNRHFYEFTPPRPLEEIDADLKQCTDRIKQMIEELSA  661
              +G+EIPF R FY +TPP P E I   +KQ  + I + ++ LS+
Sbjct  546  --IGYEIPFTRLFYKYTPPEPSEVISERIKQLEESIIKNFQALSG  588

65) hsdM [C] in NC_019902


> NC_002953_R1|4|G3|49484939|YP_042160.1|Staphylococcus_aureus_subsp._aureus_MSSA476|-|4742..6529|-|SAS0027|type 
I restriction 
enzyme methylase
Length=595

 Score =  359 bits (1349),  Expect = 3e-100, Method: Compositional matrix adjust.
 Identities = 212/475 (45%), Positives = 336/475 (71%), Gaps = 18/475 (3%)

Query  13   IWSVADLLRGDFKQSQYGRVILPFTLLRRLECVLEPTKDAVLAEAREHAGKSDSLRELLL  72
            IW+VAD+LRG +K  +YG+VILP T+++RL+  L  T+D VL  A +  + +D +RE LL
Sbjct  21   IWNVADILRGLYKPHEYGKVILPMTVIKRLHDTLLKTRDKVLKTAENTQSINDVMRERLL  80

Query  73   LRAADQPFFNTSPLSLASL--SDTQPGEDLMSYIEAFSSHAREIFDHFHFEDYVEQLASN  130
              A++ +F+NTS  ++ +L    ++   ++ +Y+++FS + ++I+++F F+  +  +A N
Sbjct  81   KNASGYSFYNTSLYTFETLLADPANIESNFRAYLNGFSENMQDILNNFKFDVEITTMADN  140

Query  131  NLLYQVVQRFAAID--LRPARLSNFGMGLVFEELIRKFAESSNETAGEHFTPRDVVHLTT  188
            ++L+ V+Q F   D  L P ++++ +MG VFEEL+RKF+ES NE AG HFT+RD++ L T
Sbjct  141  DVLFYVIQEFNKADAYLGPDKMTSTDMGYVFEELVRKFSESYNEEAGAHFTSRDIIYLMT  200

Query  189  SLVLTGQDHKL-KPHGIVTVYDPAAGTGGFLSESDEYIQQISQGVSVSLHGQELNPESYA  247
             L+L  + + L K H + TVYD + GT+  LS   E I+++++   V+  GQELNPE+YA
Sbjct  201  DLLLIEDKDTLFKEHVFKTVYDQTMGTSQMLSAMTERIHDMNDTAEVATFGQELNPETYA  260

Query  248  ICKADMLIKGQKVENIRLGNTLSDDQHAGEHFDYMLANPPFGVEWKKVQRQVTDEHQHQG  307
            I KAD +I+G   EN+ LG+TL+ D+  G  FDY ++NPPFGV+WKK Q+ V  EH+   
Sbjct  261  ISKADTMIRGGDPENMALGSTLTSDRFEGFTFDYCISNPPFGVDWKKDQKAVKAEHELGE  320

Query  308  FNGRFGPGLPRVSDGSLLFLLHLVSKMRDPREGGSRIGIVLNGSPLFTGGAGSGESEIRR  367
            + GRFG GLPRVSDG LLF L+ +SK+++     +R++I+ NGS+LF+G +G+GES IR+
Sbjct  321  L-GRFGVGLPRVSDGQLLFQLNGISKLKET----GRMAIIHNGSALFSGNPGAGESLIRQ  375

Query  368  YLLQHDMVEAIIGLPTDMFYNTGIATYIWLLNNRKPAERRGRVQLIDATQRYAKMRKSLG  427
            Y++++D +E+II LP D+FYNTGI+TYIW++ + K++ER+G+VQL+DA++ Y K RK++G
Sbjct  376  YVIENDWLEGIIQLPNDLFYNTGISTYIWIITKDKSPERQGKVQLVDASNMYEKRRKNIG  435

Query  428  SKRQYIDDANIDAIVRSYGAFGESD--------NSKIFPVDAFGYRRITVERPLR  474
             KR  I +A  + IV++YG F + +        +SKI+  ++FG+ R+T+ERP R
Sbjct  436  EKRVDISEACREMIVQAYGEFNDKEYYLGDGTVESKILKNESFGFTRVTIERPQR  490


 Score = 83.6 bits (298),  Expect = 4e-17, Method: Compositional matrix adjust.
 Identities = 57/172 (34%), Positives = 100/172 (59%), Gaps = 13/172 (7%)

Query  490  EKPIQKLGATTRLGVQAACERLDAER--VYTHREAFLSELTAQLQALDVKLPAPALKALW  547
            EK  +++G   R+++  AC  +  +    + ++E +L++ T + + L  K  + ++  + 
Sbjct  428  EKRRKNIGEK-RVDISEACREMIVQAYGEFNDKEYYLGDGTVESKIL--KNESFGFTRVT  484

Query  548  TALSERDPEADICTDKKGTPEPDSDLRDTENVPLGEDVFEYFEREVKPHVPDAWIDQDKR  607
               ++RD ++DI   K+G+   D++LRDTE++PL ED+ EYFERE+ P   DAW+D+ K 
Sbjct  485  IERPQRDENGDIVYKKNGSKSVDTNLRDTEDIPLTEDINEYFEREILPFNQDAWMDRKK-  543

Query  608  DEQDGEIGIVGFEIPFNRHFYVFQPPRPLEEIDADLKAVTTRIKQMIEELSG  659
                   + +G+EIPF R FY + PP P E I   +K +   I + ++ LSG
Sbjct  544  -------DKIGYEIPFTRLFYKYTPPEPSEVISERIKQLEESIIKNFQALSG  588

66) PSPA7_0075 in NC_009656


> NC_002953_R1|4|G3|49484939|YP_042160.1|Staphylococcus_aureus_subsp._aureus_MSSA476|-|4742..6529|-|SAS0027|type 
I restriction 
enzyme methylase
Length=595

 Score =  359 bits (1349),  Expect = 3e-100, Method: Compositional matrix adjust.
 Identities = 208/478 (44%), Positives = 343/478 (72%), Gaps = 18/478 (3%)

Query  10   AAFLWSIADLLRGDFKQSQYGRIILPFTLLRRMECVLEPTREAVIRESYAQEGRPDLVRE  69
            A ++W++AD+LRG +K  +YG++ILP T+++R++  L  TR+ V++ +   ++  D++RE
Sbjct  18   ANLIWNVADILRGLYKPHEYGKVILPMTVIKRLHDTLLKTRDKVLKTAENTQSINDVMRE  77

Query  70   RLLLRAAGQQFFNASKLTLGTL--SDTQTAADLMSYVQSFSKDAREIFEHFHFEDFVQQL  127
            RLL  A+G  F+N+S  T+ TL    ++  +++ +Y+++FS + ++I+++F F+  +  +
Sbjct  78   RLLKNASGYSFYNTSLYTFETLLADPANIESNFRAYLNGFSENMQDILNNFKFDVEITTM  137

Query  128  SAANLLYQVVQRFAATD--LSPERISNFGMGIIFEELIRKFAESSNETAGEHFTPRDIVH  185
            +  ++L+ V+Q F  +D  L+P+++++ +MG +FEEL+RKF+ES NE AG HFT+RDI+ 
Sbjct  138  ADNDVLFYVIQEFNKADAYLGPDKMTSTDMGYVFEELVRKFSESYNEEAGAHFTSRDIIY  197

Query  186  LTTSLVITGQDDKL-KPNSIVTIYDPTAGTGGFLSEGDEYIQSISQQVTVSLHGQELNPE  244
            L T L++  + D L K + + T+YD T GT+  LS   E I+ +++   V+  GQELNPE
Sbjct  198  LMTDLLLIEDKDTLFKEHVFKTVYDQTMGTSQMLSAMTERIHDMNDTAEVATFGQELNPE  257

Query  245  SYAICKADMLIKGQDVTSIKLGNTLSDDQLADSRFDFMLSNPPFGVEWKKVQKQITDEHS  304
            +YAI KAD +I+G D  ++ LG+TL+ D++ +  FD+ +SNPPFGV+WKK QK +  EH 
Sbjct  258  TYAISKADTMIRGGDPENMALGSTLTSDRFEGFTFDYCISNPPFGVDWKKDQKAVKAEH-  316

Query  305  EKGFNGRFGPGLPRVSDGSLLFLLHLVSKMRDPREGGSRIGIILNGSPLFTGGAGSGESE  364
            E G  GRFG GLPRVSDG LLF L+ +SK+++     +R++II NGS+LF+G +G+GES 
Sbjct  317  ELGELGRFGVGLPRVSDGQLLFQLNGISKLKET----GRMAIIHNGSALFSGNPGAGESL  372

Query  365  IRRYLLQNDLVEAIIALPTDMFYNTGIATYVWVLSNHKAAARQGKVQLIDGSQHFAKMRK  424
            IR+Y+++ND +E+II LP D+FYNTGI+TY+W+++++K++ RQGKVQL+D+S+ + K RK
Sbjct  373  IRQYVIENDWLEGIIQLPNDLFYNTGISTYIWIITKDKSPERQGKVQLVDASNMYEKRRK  432

Query  425  SLGSKRQYLTEEQIDALVRLYGRFEE--------TAQSKIFPVEAFGYRRITVERPLR  474
            ++G KR  ++E   + +V+ YG F++        T +SKI+  E+FG+ R+T+ERP R
Sbjct  433  NIGEKRVDISEACREMIVQAYGEFNDKEYYLGDGTVESKILKNESFGFTRVTIERPQR  490


 Score = 69.2 bits (243),  Expect = 9e-13, Method: Compositional matrix adjust.
 Identities = 42/107 (40%), Positives = 63/107 (59%), Gaps = 16/107 (14%)

Query  551  SERDSEADI-CMVKGQPEADAGLRDNENVPLGESVYDYFEREVKPHVADAWIDESKRDEQ  609
            ++RD ++DI    +G    D+ LRD E++PL E + +YFERE+ P   DAW+D  K    
Sbjct  488  PQRDENGDIVYKKNGSKSVDTNLRDTEDIPLTEDINEYFEREILPFNQDAWMDRKK----  543

Query  610  DGEVGIVGFEIPFNRHFYVFQPPRPLEEIDRDLKGCTDRIKQMIEGL  656
                + +G+EIPF R FY + PP P E I       ++RIKQ+ E++
Sbjct  544  ----DKIGYEIPFTRLFYKYTPPEPSEVI-------SERIKQLEESI  579

67) Hhal_1155 in NC_008789


> NC_002953_R1|4|G3|49484939|YP_042160.1|Staphylococcus_aureus_subsp._aureus_MSSA476|-|4742..6529|-|SAS0027|type 
I restriction 
enzyme methylase
Length=595

 Score =  359 bits (1347),  Expect = 5e-100, Method: Compositional matrix adjust.
 Identities = 213/478 (45%), Positives = 339/478 (71%), Gaps = 18/478 (3%)

Query  10   AGFIWSVADLLRGDLKQSQYGRVILPFTLLRRLECVLEPTKEQVLAAAKEHADKPLGVRE  69
            A +IW+VAD+LRG  K  +YG+VILP T+++RL+  L  T+++VL +A +       +RE
Sbjct  18   ANLIWNVADILRGLYKPHEYGKVILPMTVIKRLHDTLLKTRDKVLKTAENTQSINDVMRE  77

Query  70   RLLRRAADQPFFNTSPLTLGTL--SDTQTADDLMSYVQSFSPDAREVFEHFNFEDFVQQL  127
            RLL+ A++ +F+NTS  T+ TL    ++   ++ +Y+++FS + ++++++F+F+  +  +
Sbjct  78   RLLKNASGYSFYNTSLYTFETLLADPANIESNFRAYLNGFSENMQDILNNFKFDVEITTM  137

Query  128  SANNLLYQVVQRFAAMD--LSPGRISNFGMGSIFEELIRKFAESSNETAGEHFTPRDVVH  185
            + N++L+ V+Q F   D  L+P+++++ +MG +FEEL+RKF+ES NE AG HFT+RD++ 
Sbjct  138  ADNDVLFYVIQEFNKADAYLGPDKMTSTDMGYVFEELVRKFSESYNEEAGAHFTSRDIIY  197

Query  186  LTTSLVLTDQDDKL-QPHSVVTVYDPAAGTGGFLSESDAYIQQVSDNVTVSLHGQELNPE  244
            L T L+L ++ D L + H   TVYD + GT+  LS     I++++D   V+  GQELNPE
Sbjct  198  LMTDLLLIEDKDTLFKEHVFKTVYDQTMGTSQMLSAMTERIHDMNDTAEVATFGQELNPE  257

Query  245  SYAICKADMLIKGQQVENIKLGNTLSDDELAGERFDFMLANPPFGVEWKKVQKQVTDEHK  304
            +YAI KAD +I+G + EN+ LG+TL+ D + G  FD+ ++NPPFGV+WKK QK V  EH 
Sbjct  258  TYAISKADTMIRGGDPENMALGSTLTSDRFEGFTFDYCISNPPFGVDWKKDQKAVKAEHE  317

Query  305  RWGYNGRFGPGLPRVSDGSLLFLLHLVSKVRDPREGGSRIGIILNGSPLFTGGAGSGESE  364
              G  GRFG GLPRVSDG LLF L+ +SK+++     +R++II NGS+LF+G +G+GES 
Sbjct  318  L-GELGRFGVGLPRVSDGQLLFQLNGISKLKET----GRMAIIHNGSALFSGNPGAGESL  372

Query  365  IRRFLLERDLVEAIVALPTDMFYNTGIATYVWILSNDKPPERRGRVQLINATERYSKMRK  424
            IR++++E D +E+I+ LP D+FYNTGI+TY+WI+++DK+PER+G+VQL++A++ Y K RK
Sbjct  373  IRQYVIENDWLEGIIQLPNDLFYNTGISTYIWIITKDKSPERQGKVQLVDASNMYEKRRK  432

Query  425  SLGSKRQYIDDTNIDNIVRLYGAFEESE--------ESKLFPVAEFGYRRITVERPLR  474
            ++G KR  I ++  + IV+ YG F++ E        ESK++    FG+ R+T+ERP R
Sbjct  433  NIGEKRVDISEACREMIVQAYGEFNDKEYYLGDGTVESKILKNESFGFTRVTIERPQR  490


 Score = 74.4 bits (263),  Expect = 2e-14, Method: Compositional matrix adjust.
 Identities = 44/109 (41%), Positives = 66/109 (61%), Gaps = 8/109 (7%)

Query  551  SERDPEAKPCTDAKGNPEPDTSLRDHENVPLTESVYDYFEREVRPHVPDAWIDEAKRDAQ  610
            ++RD ++      +G+   DT+LRD E++PLTE + +YFERE+ P   DAW+D  K    
Sbjct  488  PQRDENGDIVYKKNGSKSVDTNLRDTEDIPLTEDINEYFEREILPFNQDAWMDRKK----  543

Query  611  DGEVGIVGYEIPFNRHFYKFTPPRPLEEIDADLKVCTDRIKRMIEELSA  659
                + +GYEIPF R FYK+TPP P E I   +K   + I + ++ LS+
Sbjct  544  ----DKIGYEIPFTRLFYKYTPPEPSEVISERIKQLEESIIKNFQALSG  588

68) B005_4037 in NC_018524


> NC_002953_R1|4|G3|49484939|YP_042160.1|Staphylococcus_aureus_subsp._aureus_MSSA476|-|4742..6529|-|SAS0027|type 
I restriction 
enzyme methylase
Length=595

 Score =  358 bits (1346),  Expect = 6e-100, Method: Compositional matrix adjust.
 Identities = 226/491 (47%), Positives = 339/491 (70%), Gaps = 22/491 (4%)

Query  7    QELVSFIWSVADLLRGDYKQSEYGKAILPFVVLRRLDCVLEPKKKKVLAAHEKWKD-KPV  65
            Q   ++IW+VAD+LRG YK  EYGK ILP  V++RL+  L   + KVL + E+ +  + V
Sbjct  15   QKQANLIWNVADILRGLYKPHEYGKVILPMTVIKRLHDTLLKTRDKVLKTAENTQSINDV  74

Query  66   HHEFLLK-ASGRSFYNTSPLTFERIGADPSQAANNLGHFINAFSDNAREVLEKYEFPRQI  124
             +E LLK ASG SFYNTS  TFE + ADP++  +N+  ++N+FS+N +++L+++ F  +I
Sbjct  75   MRERLLKNASGYSFYNTSLYTFETLLADPANIESNFRAYLNGFSENMQDILNNFKFDVEI  134

Query  125  QRLDAAGLLYQVVGRFADLD--LSPERVSNVQMGYVFEELIRKFSEISNETAGEHFTPRE  182
              +   ++L+ V+  F   D  L+P+++++ +MGYVFEEL+RKFSE  NE AG HFT+R+
Sbjct  135  TTMADNDVLFYVIQEFNKADAYLGPDKMTSTDMGYVFEELVRKFSESYNEEAGAHFTSRD  194

Query  183  VIKLMANLLLAPDEDSLRGPGVIKEILDPACGTGGMLTEMHDHIKALNPDARAVVFGQEL  242
            +I LM++LLL  D D+L    V+K + D + GT+ ML+ M ++I  +N  A    FGQEL
Sbjct  195  IIYLMTDLLLIEDKDTLFKEHVFKTVYDQTMGTSQMLSAMTERIHDMNDTAEVATFGQEL  254

Query  243  NPESWAICRSDLMIKGQSPENIRFGNSFSDDRHRYGTFDYMLANPPFGVEWKKVKDDVEA  302
            NPE+ AI ++D MI+G  PEN+ +G++++ DR    TFDY ++NPPFGV+WKK +  V A
Sbjct  255  NPETYAISKADTMIRGGDPENMALGSTLTSDRFEGFTFDYCISNPPFGVDWKKDQKAVKA  314

Query  303  EHELGASGRFGAGLPRINDGSLLFLQHMISKMKPVKLDEEGEKRGGSRIAIVFNGSPLFT  362
            EHELG  GRFG GLPR++DG LLF  + ISK+K             +R+AI+ NGS+LF+
Sbjct  315  EHELGELGRFGVGLPRVSDGQLLFQLNGISKLK-----------ETGRMAIIHNGSALFS  363

Query  363  GAAGSGESEIRRWILENDWLEAIVALPDQLFYNTGISTYFWVLTNRKDRAHEGKVKLVDA  422
            G +G+GES IR+ ++ENDWLE+I+ LP++LFYNTGISTY+W++T+ K   ++GKV+LVDA
Sbjct  364  GNPGAGESLIRQYVIENDWLEGIIQLPNDLFYNTGISTYIWIITKDKSPERQGKVQLVDA  423

Query  423  REHWTKMRKSLGEKRKEIGKEQITELTRLYADALGVAEDPEHPL-HGKV--KVFRNEDFG  479
             +   K RK++GEKR +I+      + + Y++     +D E  L +G V  K+++NE FG
Sbjct  424  SNMYEKRRKNIGEKRVDISEACREMIVQAYGE----FNDKEYYLGDGTVESKILKNESFG  479

Query  480  YQRITVERPLK  490
            + R+T+ERP +
Sbjct  480  FTRVTIERPQR  490


 Score = 85.7 bits (306),  Expect = 1e-17, Method: Compositional matrix adjust.
 Identities = 50/92 (55%), Positives = 63/92 (69%), Gaps = 1/92 (1%)

Query  572  RDPEGEVQ-KKKGEPEPDPDLRDFENIPLDEDIDLYMEREVLPHVPDAWVEYAKTKIGYE  630
            RD +G++  KK+G    D +LRD E+IPL EDI+ Y ERE+LP   DAW++  K KIGYE
Sbjct  490  RDENGDIVYKKNGSKSVDTNLRDTEDIPLTEDINEYFEREILPFNQDAWMDRKKDKIGYE  549

Query  631  IPFTRHFYVYTPPRPLEEIDAELKELEGEIQR  662
            IPFTR FY YTPP P E I   +K+LE  I +
Sbjct  550  IPFTRLFYKYTPPEPSEVISERIKQLEESIIK  581

69) PSTAA_0900 in NC_017532


> NC_002953_R1|4|G3|49484939|YP_042160.1|Staphylococcus_aureus_subsp._aureus_MSSA476|-|4742..6529|-|SAS0027|type 
I restriction 
enzyme methylase
Length=595

 Score =  357 bits (1341),  Expect = 1e-99, Method: Compositional matrix adjust.
 Identities = 210/480 (44%), Positives = 344/480 (72%), Gaps = 20/480 (4%)

Query  10   AAFLWSIADLLRGDFKQSQYGRIILPFTLLRRMECVLEPTKEAVIRESYAQEGRPDLVRE  69
            A ++W++AD+LRG +K  +YG++ILP T+++R++  L  T++ V++ +   ++  D++RE
Sbjct  18   ANLIWNVADILRGLYKPHEYGKVILPMTVIKRLHDTLLKTRDKVLKTAENTQSINDVMRE  77

Query  70   RLLLRAAGQQFFNASKLTLGTL--SDTQTAADLMSYVQSFSKDAREIFEHFHFEDFVQQL  127
            RLL  A+G  F+N+S  T+ TL    ++  +++ +Y+++FS + ++I+++F F+  +  +
Sbjct  78   RLLKNASGYSFYNTSLYTFETLLADPANIESNFRAYLNGFSENMQDILNNFKFDVEITTM  137

Query  128  SAANLLYQVVQRFAATD--LSPERISNFGMGIIFEELIRKFAESSNETAGEHFTPRDIVH  185
            +  ++L+ V+Q F  +D  L+P+++++ +MG +FEEL+RKF+ES NE AG HFT+RDI+ 
Sbjct  138  ADNDVLFYVIQEFNKADAYLGPDKMTSTDMGYVFEELVRKFSESYNEEAGAHFTSRDIIY  197

Query  186  LTTSLVITGQDDKL-KPNSIVTIYDPTAGTGGFLSEGDEYIQSISQQVTVSLHGQELNPE  244
            L T L++  + D L K + + T+YD T GT+  LS   E I+ +++   V+  GQELNPE
Sbjct  198  LMTDLLLIEDKDTLFKEHVFKTVYDQTMGTSQMLSAMTERIHDMNDTAEVATFGQELNPE  257

Query  245  SYAICKADMLIKGQKVENIKLGNTLSDDQLTGAEHHFDFMLSNPPFGVEWKKVQKQITDE  304
            +YAI KAD +I+G   EN+ LG+TL+ D++ G    FD+ +SNPPFGV+WKK QK +  E
Sbjct  258  TYAISKADTMIRGGDPENMALGSTLTSDRFEG--FTFDYCISNPPFGVDWKKDQKAVKAE  315

Query  305  HSEKGFNGRFGPGLPRVSDGSLLFLLHLVSKMRDPREGGSRIGIILNGSPLFTGGAGSGE  364
            H E G  GRFG GLPRVSDG LLF L+ +SK+++     +R++II NGS+LF+G +G+GE
Sbjct  316  H-ELGELGRFGVGLPRVSDGQLLFQLNGISKLKET----GRMAIIHNGSALFSGNPGAGE  370

Query  365  SEIRRYLLQNDLVEAIIALPTDMFYNTGIATYVWVLSNHKAAERQGKVQLIDGSQHFGKM  424
            S IR+Y+++ND +E+II LP D+FYNTGI+TY+W+++++K++ERQGKVQL+D+S+ + K 
Sbjct  371  SLIRQYVIENDWLEGIIQLPNDLFYNTGISTYIWIITKDKSPERQGKVQLVDASNMYEKR  430

Query  425  RKSLGSKRQYITDEQIDELVRLYGRFEE--------TAQSKIFPVEAFGYRRITVERPLR  476
            RK++G KR  I++   + +V+ YG F++        T +SKI+  E+FG+ R+T+ERP R
Sbjct  431  RKNIGEKRVDISEACREMIVQAYGEFNDKEYYLGDGTVESKILKNESFGFTRVTIERPQR  490


 Score = 68.7 bits (241),  Expect = 1e-12, Method: Compositional matrix adjust.
 Identities = 41/109 (38%), Positives = 62/109 (57%), Gaps = 9/109 (8%)

Query  553  SERDPEADICLVK-GKPEADAGLRDNENVPLGESVYDYFEREVKPHVPDAWIDESKTDAQ  611
            ++RD ++DI   K G    D+ LRD E++PL E + +YFERE+ P   DAW+D  K    
Sbjct  488  PQRDENGDIVYKKNGSKSVDTNLRDTEDIPLTEDINEYFEREILPFNQDAWMDRKKDK--  545

Query  612  DGEVGVVGFEIPFNRHFYVFQPPRPLADIDRDLKACTDRIKQMIEGLSA  660
                  +G+EIPF R FY + PP P   I   +K   + I + +++LS+
Sbjct  546  ------IGYEIPFTRLFYKYTPPEPSEVISERIKQLEESIIKNFQALSG  588

70) BLASA_2167 in NC_016943


> NC_002953_R1|4|G3|49484939|YP_042160.1|Staphylococcus_aureus_subsp._aureus_MSSA476|-|4742..6529|-|SAS0027|type 
I restriction 
enzyme methylase
Length=595

 Score =  356 bits (1338),  Expect = 2e-99, Method: Compositional matrix adjust.
 Identities = 214/480 (45%), Positives = 328/480 (69%), Gaps = 12/480 (2%)

Query  5    EGKVQFVWQVADLLRGDYKPAEYRGVILPLLVLRRLDAVLEESKPAVLARAEQLKGVTD-  63
            + + +++W+VAD+LRG YKP EY  VILP+ V++RL+  L  ++  VL  AE+ +++ D 
Sbjct  15   QKQANLIWNVADILRGLYKPHEYGKVILPMTVIKRLHDTLLKTRDKVLKTAENTQSINDV  74

Query  64   NPDVLLRDAAGVPFYNVSPLTFTKLLDSPNNLAQQLRAYIGAFSPGAAQVLEKYRFDEQI  123
              + LL++A+G +FYN S  TF  LL  P N+  ++RAY+ +FS    ++L++++FD +I
Sbjct  75   MRERLLKNASGYSFYNTSLYTFETLLADPANIESNFRAYLNGFSENMQDILNNFKFDVEI  134

Query  124  SRLDDAGLLYLVLGKFADLD--LRPEVVPNHAMGYIFEELLRRFSELSNETAGEHFTPRE  181
            + + D ++L+ V+  F   D  L P+ + +  MGY+FEEL+R+FSE  NE AG HFT+R+
Sbjct  135  TTMADNDVLFYVIQEFNKADAYLGPDKMTSTDMGYVFEELVRKFSESYNEEAGAHFTSRD  194

Query  182  VIRLIVNLLFGEDSDVLTGTAPVRSIYDPACGTGGMLNIADQYLTRLNPKARLEMFGQEL  241
            +I L+ +LL+ ED D L      +++YD + GT+ ML+   + +  +N  A +  FGQEL
Sbjct  195  IIYLMTDLLLIEDKDTLFKEHVFKTVYDQTMGTSQMLSAMTERIHDMNDTAEVATFGQEL  254

Query  242  NPETWAIARSDLLIQGQDPERIVLGNTLTADGHADKRFDYLLANPPFGVDWNKSaaaika  301
            NPET AI+++D +I+G DPE + LG+TLT+D   +  FDY ++NPPFGVDW+K   A+KA
Sbjct  255  NPETYAISKADTMIRGGDPENMALGSTLTSDRFEGFTFDYCISNPPFGVDWKKDQKAVKA  314

Query  302  eaaQPG-GRFSAGLPRVSDGSLLFLQQMIARMKPAEDGGSRVAIVFSGSPLFAGAAESGE  360
            E      GRF+ GLPRVSDG LLF  + I+++K +    +R+AI+ +GS+LF+G + +GE
Sbjct  315  EHELGELGRFGVGLPRVSDGQLLFQLNGISKLKET----GRMAIIHNGSALFSGNPGAGE  370

Query  361  SNIRRWIIENDWLEGIVALPDQLFYNTGISTYVWIVTNRKRPEREGKVALIDARGEWSKM  420
            S IR+ +IENDWLEGI+ LP++LFYNTGISTY+WI+T+ K PER+GKV L+DA     K 
Sbjct  371  SLIRQYVIENDWLEGIIQLPNDLFYNTGISTYIWIITKDKSPERQGKVQLVDASNMYEKR  430

Query  421  RKSLGDKRKYLDDAHIEEITRLYHDAPE----LTDADERVKVFHDDVFGFRRITVERPLR  476
            RK++G+KR  + +A  E I + Y +  +    L D+    K++ ++ FGF R+T+ERP R
Sbjct  431  RKNIGEKRVDISEACREMIVQAYGEFNDKEYYLGDGTVESKILKNESFGFTRVTIERPQR  490


 Score = 88.1 bits (315),  Expect = 2e-18, Method: Compositional matrix adjust.
 Identities = 44/87 (51%), Positives = 60/87 (69%), Gaps = 0/87 (0%)

Query  571  KKGEPLPDPDLRDNENVPLTEDVDEYVEREVLPHVPDAWVDHTKTKIGYEIPFTRFFYRY  630
            K+G    D +LRD E++PLTED++EY ERE+LP   DAW+D+ K KIGYEIPFTR+FY+Y
Sbjct  500  KNGSKSVDTNLRDTEDIPLTEDINEYFEREILPFNQDAWMDRKKDKIGYEIPFTRLFYKY  559

Query  631  VPPRPLAEIDAELEAVEAEIRRVLAGL  657
             PP P   I   +  +E  I + + +L
Sbjct  560  TPPEPSEVISERIKQLEESIIKNFQAL  586

71) Maqu_0413 in NC_008740


> NC_002953_R1|4|G3|49484939|YP_042160.1|Staphylococcus_aureus_subsp._aureus_MSSA476|-|4742..6529|-|SAS0027|type 
I restriction 
enzyme methylase
Length=595

 Score =  356 bits (1339),  Expect = 2e-99, Method: Compositional matrix adjust.
 Identities = 210/485 (44%), Positives = 345/485 (72%), Gaps = 18/485 (3%)

Query  3    HDKTNHSQTAAFIWSVADLLRGDFKQSQYGRVILPFTLLRRLECVLEPTKAQVLSAAQEH  62
            +   N  + A +IW+VAD+LRG +K  +YG+VILP T+++RL+  L  T+ +VL +A++ 
Sbjct  9    QTSINVQKQANLIWNVADILRGLYKPHEYGKVILPMTVIKRLHDTLLKTRDKVLKTAENT  68

Query  63   QTKPDAVREKLLLRAADQQFFNASPLSLATL--SDSQTADDLMSYVQSFSQDAREIFEHF  120
            Q+  D +RE+LL  A++  F+N+S  ++ TL    ++   ++ +Y+++FS++ ++I+++F
Sbjct  69   QSINDVMRERLLKNASGYSFYNTSLYTFETLLADPANIESNFRAYLNGFSENMQDILNNF  128

Query  121  HFEDFVQQLSANNLLYQVVQRFASID--LSPATISNFGMGIIFEELIRKFAESSNETAGE  178
             F+  +  ++ N++L+ V+Q F   D  L+P  +++ +MG +FEEL+RKF+ES NE AG 
Sbjct  129  KFDVEITTMADNDVLFYVIQEFNKADAYLGPDKMTSTDMGYVFEELVRKFSESYNEEAGA  188

Query  179  HFTPRDIVHLTTSLVLTGQENRLTPNSIV-TIYDPTAGTGGFLSEGDEYIQQISESVTVS  237
            HFT+RDI+ L T L+L  + + L  + +  T+YD T GT+  LS   E I++++++  V+
Sbjct  189  HFTSRDIIYLMTDLLLIEDKDTLFKEHVFKTVYDQTMGTSQMLSAMTERIHDMNDTAEVA  248

Query  238  LHGQELNPESYAICKADMLIKGQEVSNIKLGNTLSDDQLATNKFDLMLSNPPFGVEWKKV  297
              GQELNPE+YAI KAD +I+G +  N+ LG+TL+ D++    FD  +SNPPFGV+WKK 
Sbjct  249  TFGQELNPETYAISKADTMIRGGDPENMALGSTLTSDRFEGFTFDYCISNPPFGVDWKKD  308

Query  298  QKQVTDEHKHRGFAGRFGPGLPRVSDGSLLFLMHLVSKMRDAREGGSRIGIILNGSPLFT  357
            QK V  EH    + GRFG GLPRVSDG LLF ++ +SK++++    +R++II NGS+LF+
Sbjct  309  QKAVKAEHELGEL-GRFGVGLPRVSDGQLLFQLNGISKLKET----GRMAIIHNGSALFS  363

Query  358  GGAGSGESEIRRYLLQNDMVEAIVALPTDMFYNTGISTYVWVLSNNKPAERKSKVQLIDA  417
            G +G+GES IR+Y+++ND +E+I+ LP D+FYNTGISTY+W+++++K++ER++KVQL+DA
Sbjct  364  GNPGAGESLIRQYVIENDWLEGIIQLPNDLFYNTGISTYIWIITKDKSPERQGKVQLVDA  423

Query  418  TDRATKMRKSLGSKRQFVSESDQDEIVRMYGDFQE--------TKKSKIFPIEAFGYRRI  469
            ++   K RK++G KR  +SE+ ++ IV+ YG+F++        T  SKI+  E+FG+ R+
Sbjct  424  SNMYEKRRKNIGEKRVDISEACREMIVQAYGEFNDKEYYLGDGTVESKILKNESFGFTRV  483

Query  470  TVERP  474
            T+ERP
Sbjct  484  TIERP  488


 Score = 76.5 bits (271),  Expect = 5e-15, Method: Compositional matrix adjust.
 Identities = 43/109 (40%), Positives = 68/109 (63%), Gaps = 8/109 (7%)

Query  553  SERDPEADICTDSKGNPEADTGLRDYENVPLSESVYDYFEREVKPHVPDVWIDESKRDEK  612
            ++RD ++DI    +G+   DT LRD E++PL+E + +YFERE+ P   D W+D  ++ +K
Sbjct  488  PQRDENGDIVYKKNGSKSVDTNLRDTEDIPLTEDINEYFEREILPFNQDAWMD--RKKDK  545

Query  613  DGEVGIVGFEIPFNRHFYEFTPPRPLEEIDADLKQCTDRIKQMIEELSA  661
                  +G+EIPF R FY +TPP P E I   +KQ  + I + ++ LS+
Sbjct  546  ------IGYEIPFTRLFYKYTPPEPSEVISERIKQLEESIIKNFQALSG  588

72) PSF113_5184 in NC_016830


> NC_002953_R1|4|G3|49484939|YP_042160.1|Staphylococcus_aureus_subsp._aureus_MSSA476|-|4742..6529|-|SAS0027|type 
I restriction 
enzyme methylase
Length=595

 Score =  355 bits (1334),  Expect = 5e-99, Method: Compositional matrix adjust.
 Identities = 211/497 (43%), Positives = 348/497 (71%), Gaps = 21/497 (4%)

Query  10   AAFLWSIADLLRGDFKQSQYGRIILPFTLLRRMECVLAPTKDEVIKQTFAQEGRPDTVRE  69
            A ++W++AD+LRG +K  +YG++ILP T+++R++  L  T+D V+K +   ++  D +RE
Sbjct  18   ANLIWNVADILRGLYKPHEYGKVILPMTVIKRLHDTLLKTRDKVLKTAENTQSINDVMRE  77

Query  70   MILLRSAGQQFFNASPLTLGTL--SDTQTAADLMNYVQAFSKDAREIFEHFHFEDFVQQL  127
             +L  ++G  F+N+S  T+ TL    ++  +++  Y+++FS + ++I+++F F+  +  +
Sbjct  78   RLLKNASGYSFYNTSLYTFETLLADPANIESNFRAYLNGFSENMQDILNNFKFDVEITTM  137

Query  128  SSANLLYQVVQRFAATD--LSPERISNFGMGIIFEELIRKFAESSNETAGEHFTPRDIVH  185
            +  ++L+ V+Q F  +D  L+P+++++ +MG +FEEL+RKF+ES NE AG HFT+RDI+ 
Sbjct  138  ADNDVLFYVIQEFNKADAYLGPDKMTSTDMGYVFEELVRKFSESYNEEAGAHFTSRDIIY  197

Query  186  LTTSLVITNQDHKL-TPNSIVTIYDPTAGTGGFLSEGDEYIQSISEKVSVSLHGQELNPE  244
            L T L++ ++ + L   + + T+YD T GT+  LS   E I+ +++   V+  GQELNPE
Sbjct  198  LMTDLLLIEDKDTLFKEHVFKTVYDQTMGTSQMLSAMTERIHDMNDTAEVATFGQELNPE  257

Query  245  SYAICKADMLIKGQDVVSIKLGNTLSNDQLAGKRFDFMLSNPPFGVEWKKVQKQITDEHT  304
            +YAI KAD +I+G D  ++ LG+TL++D++ G  FD+ +SNPPFGV+WKK QK +  EH 
Sbjct  258  TYAISKADTMIRGGDPENMALGSTLTSDRFEGFTFDYCISNPPFGVDWKKDQKAVKAEHE  317

Query  305  HRGFDGRFGPGLPRVSDGSLLFLLHLVSKMRDPRDGGSRIGIILNGSPLFSGGAGSGESE  364
               + GRFG GLPRVSDG LLF L+ +SK+++     +R++II NGS+LFSG +G+GES 
Sbjct  318  LGEL-GRFGVGLPRVSDGQLLFQLNGISKLKET----GRMAIIHNGSALFSGNPGAGESL  372

Query  365  IRRYLLQNDLVEAIVALPTDMFYNTGIATYIWILSNHKVAARQGKVQLIDGSQHYAKMRK  424
            IR+Y+++ND +E+I+ LP D+FYNTGI+TYIWI++++K + RQGKVQL+D+S+ Y K RK
Sbjct  373  IRQYVIENDWLEGIIQLPNDLFYNTGISTYIWIITKDKSPERQGKVQLVDASNMYEKRRK  432

Query  425  SLGSKRQYITEDQISELVRLYGSFEH--------TSQSKIFPIDAFGYRRITVERPLRLN  476
            ++G KR  I+E     +V+ YG F++        T +SKI+  ++FG+ R+T+ERP R  
Sbjct  433  NIGEKRVDISEACREMIVQAYGEFNDKEYYLGDGTVESKILKNESFGFTRVTIERPQR--  490

Query  477  FQTNAERLYKVLEEKSL  493
             + N++ +YK    KS+
Sbjct  491  -DENGDIVYKKNGSKSV  506


 Score = 73.9 bits (261),  Expect = 3e-14, Method: Compositional matrix adjust.
 Identities = 40/109 (37%), Positives = 66/109 (61%), Gaps = 9/109 (8%)

Query  551  SERDPEADI-CTTKGQPEADASLRDNENVPLGESVYDYFQREVIPHVQDAWIDESKTDAQ  609
            ++RD ++DI    +G    D++LRD E++PL E + +YF+RE++P  QDAW+D  K    
Sbjct  488  PQRDENGDIVYKKNGSKSVDTNLRDTEDIPLTEDINEYFEREILPFNQDAWMDRKKDK--  545

Query  610  DGEVGIVGFEIPFNRHFYVFQPPRPLAEIDHDLKACTDRIKQMIEGLSA  658
                  +G+EIPF R FY + PP P   I + +K   + I + +++LS+
Sbjct  546  ------IGYEIPFTRLFYKYTPPEPSEVISERIKQLEESIIKNFQALSG  588

73) Mycsm_01239 in NC_019966


> NC_002953_R1|4|G3|49484939|YP_042160.1|Staphylococcus_aureus_subsp._aureus_MSSA476|-|4742..6529|-|SAS0027|type 
I restriction 
enzyme methylase
Length=595

 Score =  355 bits (1334),  Expect = 5e-99, Method: Compositional matrix adjust.
 Identities = 225/541 (42%), Positives = 351/541 (65%), Gaps = 29/541 (5%)

Query  2    TQTNANLIWKIADLLRGPYQPNQYGDVILPFTILRRLDCILEPTKAEVLAEYKKIASTKV  61
             Q +ANLIW++AD+LRG Y+P++YG VILP T+++RL+  L  T+  VL   K   +T+ 
Sbjct  14   VQKQANLIWNVADILRGLYKPHEYGKVILPMTVIKRLHDTLLKTRDKVL---KTAENTQS  70

Query  62   DPDVM----LKAKFKLPFYNISRWSFASLISDPEGVADNLVDYIEHFSRNVRDVFDGFRM  117
              DVM    LK     +FYN S  +F +L++DP  +  N+  Y++ FS N++D+++ F+ 
Sbjct  71   INDVMRERLLKNASGYSFYNTSLYTFETLLADPANIESNFRAYLNGFSENMQDILNNFKF  130

Query  118  MDQIADLAKSDRLYLIVKEFAAVD--LHPKVISGHAMGHIFEELIRKFAESNSTQAGDHF  175
              +I+ +A +D L+ +++EF   D  L P  +++  MG +FEEL+RKF+ES + +AG HF
Sbjct  131  DVEITTMADNDVLFYVIQEFNKADAYLGPDKMTSTDMGYVFEELVRKFSESYNEEAGAHF  190

Query  176  TPREVIELMVDILFQTQDDVLTKPGTVRTIYDPAAGTGGMLSTAYDHLVEMNPKARPVLF  235
            T+R++I LM D+L+  + D L K    +T+YD + GT+ MLS+  +++ +MN  A    F
Sbjct  191  TSRDIIYLMTDLLLIEDKDTLFKEHVFKTVYDQTMGTSQMLSAMTERIHDMNDTAEVATF  250

Query  236  GQDINPRSYALCKSDMIIKGQDVDNIYLGDTLTDDGFRTKHFDFLLSNPPFGVAWNTQQK  295
            GQ++NP +YA+ K+D +I+G D +N+ LG TLT D F    FD+ +SNPPFGV W+ +QK
Sbjct  251  GQELNPETYAISKADTMIRGGDPENMALGSTLTSDRFEGFTFDYCISNPPFGVDWKKDQK  310

Query  296  MVSDEYEQRGFAGRFGPGLPRVSDGSLLFLLHLISKMQPVKSGEGGSRLAIVLNGSPLFT  355
             V  E E   + GRFG GLPRVSDG LLF L+ ISK++        +R+AI+ NGS+LF+
Sbjct  311  AVKAEHELGEL-GRFGVGLPRVSDGQLLFQLNGISKLK------ETGRMAIIHNGSALFS  363

Query  356  GGAGSGESNIRQWIIENDLLDAIIALPPDMFYNTGISTYIWILDNNKPSKRKGKVQLINA  415
            G +G+GES IRQ +IEND L++II LP D+FYNTGISTYIWI+ ++K++ R+GKVQL++A
Sbjct  364  GNPGAGESLIRQYVIENDWLEGIIQLPNDLFYNTGISTYIWIITKDKSPERQGKVQLVDA  423

Query  416  VDMFGKMRKSLGAKRKELRQKDIQRICHLYDGFRN-EHGTDEHPAVSKVIKGEEFGYSTI  474
             +M+ K RK++G KR ++ +   + I + Y+ F + E   ++    SK++K E FG++ +
Sbjct  424  SNMYEKRRKNIGEKRVDISEACREMIVQAYGEFNDKEYYLGDGTVESKILKNESFGFTRV  483

Query  475  TVERPLQLRFTPTEDKIEEVLAQKSID-KLKDGEKTAIRKALTGLIGWE--------WKD  525
            T+ERP +       D +    + KS+D +L+D E  ++   +   + +E        W D
Sbjct  484  TIERPQR---DENGDIVYKKNGSKSVDTNLRDTEDIPLTEDINEYFEREILPFNQDAWMD  540

Query  526  R  526
            R
Sbjct  541  R  541


 Score = 90.2 bits (323),  Expect = 4e-19, Method: Compositional matrix adjust.
 Identities = 49/90 (55%), Positives = 63/90 (70%), Gaps = 0/90 (0%)

Query  560  HDDDAVIVTDSKGNPEPDSALRDTENVPLTEDINEYFAREVLPHVPDAWIDYDKTKIGYE  619
            +D+++ IV   +G+   D+ LRDTE++PLTEDINEYF RE+LP   DAW+D  K KIGYE
Sbjct  490  RDENGDIVYKKNGSKSVDTNLRDTEDIPLTEDINEYFEREILPFNQDAWMDRKKDKIGYE  549

Query  620  IPFTRHFYRYVPPRPLERIQKDLRVLVGEI  649
            IPFTR FY+Y PP P E I   ++ L   I
Sbjct  550  IPFTRLFYKYTPPEPSEVISERIKQLEESI  579

74) PST_0647 in NC_009434


> NC_002953_R1|4|G3|49484939|YP_042160.1|Staphylococcus_aureus_subsp._aureus_MSSA476|-|4742..6529|-|SAS0027|type 
I restriction 
enzyme methylase
Length=595

 Score =  352 bits (1323),  Expect = 4e-98, Method: Compositional matrix adjust.
 Identities = 206/478 (44%), Positives = 338/478 (71%), Gaps = 18/478 (3%)

Query  10   AAFLWSIADLLRGDFKQSQYGRIILPFTLLRRMECVLAPTKEEVVKQTFAQEGRPDTVRE  69
            A ++W++AD+LRG +K  +YG++ILP T+++R++  L  T++ V+K +   ++  D +RE
Sbjct  18   ANLIWNVADILRGLYKPHEYGKVILPMTVIKRLHDTLLKTRDKVLKTAENTQSINDVMRE  77

Query  70   MFLLRAAGQQFFNASPLTLGTL--SDTQTAADLMSYVQAFSKDAREIFEHFHFEDFVQQL  127
             +L  A+G  F+N+S  T+ TL    ++  +++ +Y+++FS + ++I+++F F+  +  +
Sbjct  78   RLLKNASGYSFYNTSLYTFETLLADPANIESNFRAYLNGFSENMQDILNNFKFDVEITTM  137

Query  128  ASANLLYQVVQRFAATD--LSPERISNFGMGIIFEELIRKFAESSNETAGEHFTPRDIVH  185
            A  ++L+ V+Q F  +D  L+P+++++ +MG +FEEL+RKF+ES NE AG HFT+RDI+ 
Sbjct  138  ADNDVLFYVIQEFNKADAYLGPDKMTSTDMGYVFEELVRKFSESYNEEAGAHFTSRDIIY  197

Query  186  LTTSLVITGQDGKL-QPNSIVTIYDPTAGTGGFLSEGDEYIQSISDKVSVSLHGQELNPE  244
            L T L++  + + L + + + T+YD T GT+  LS   E I+ ++D   V+  GQELNPE
Sbjct  198  LMTDLLLIEDKDTLFKEHVFKTVYDQTMGTSQMLSAMTERIHDMNDTAEVATFGQELNPE  257

Query  245  SYAICKADMLIKGQDVASIKLGNTLSDDQLAGQRFDFMLSNPPFGVEWKKVQKQITDEHS  304
            +YAI KAD +I+G D  ++ LG+TL+ D++ G  FD+ +SNPPFGV+WKK QK +  EH 
Sbjct  258  TYAISKADTMIRGGDPENMALGSTLTSDRFEGFTFDYCISNPPFGVDWKKDQKAVKAEHE  317

Query  305  HKGFDGRFGPGLPRVSDGSLLFLLHLVSKMRDPRDGGSRIGIILNGSPLFTGGAGSGESE  364
               + GRFG GLPRVSDG LLF L+ +SK+++     +R++II NGS+LF+G +G+GES 
Sbjct  318  LGEL-GRFGVGLPRVSDGQLLFQLNGISKLKET----GRMAIIHNGSALFSGNPGAGESL  372

Query  365  IRRYLLQNDLVEAIVALPTDMFYNTGIATYVWILSNHKVAARKGKVQLIDGSQHYSKMRK  424
            IR+Y+++ND +E+I+ LP D+FYNTGI+TY+WI++++K + R+GKVQL+D+S+ Y K RK
Sbjct  373  IRQYVIENDWLEGIIQLPNDLFYNTGISTYIWIITKDKSPERQGKVQLVDASNMYEKRRK  432

Query  425  SLGSKRQYITEDQISELVRLYGSFEQ--------TAQSKIFPIETFGYRRITVERPLR  474
            ++G KR  I+E     +V+ YG F++        T +SKI+  E+FG+ R+T+ERP R
Sbjct  433  NIGEKRVDISEACREMIVQAYGEFNDKEYYLGDGTVESKILKNESFGFTRVTIERPQR  490


 Score = 68.1 bits (239),  Expect = 2e-12, Method: Compositional matrix adjust.
 Identities = 39/109 (36%), Positives = 62/109 (57%), Gaps = 9/109 (8%)

Query  551  SERDPEADI-CTTKGQPEADSGLRDNENVPLGESVFDYFEREVKPHVPDAWIDTSKTDGQ  609
            ++RD ++DI    +G    D+ LRD E++PL E + +YFERE+ P   DAW+D  K    
Sbjct  488  PQRDENGDIVYKKNGSKSVDTNLRDTEDIPLTEDINEYFEREILPFNQDAWMDRKKDK--  545

Query  610  DGEVGVVGFEIPFNRHFYVFQPPRSLADIDRDLKACTDRIKQMIEGLSA  658
                  +G+EIPF R FY + PP +   I   +K   + I + +++LS+
Sbjct  546  ------IGYEIPFTRLFYKYTPPEPSEVISERIKQLEESIIKNFQALSG  588

75) Psest_0874 in NC_019936


> NC_002953_R1|4|G3|49484939|YP_042160.1|Staphylococcus_aureus_subsp._aureus_MSSA476|-|4742..6529|-|SAS0027|type 
I restriction 
enzyme methylase
Length=595

 Score =  351 bits (1317),  Expect = 1e-97, Method: Compositional matrix adjust.
 Identities = 203/478 (43%), Positives = 339/478 (71%), Gaps = 18/478 (3%)

Query  10   AAFLWSIADLLRGDFKQSQYGRIILPFTLLRRMECVLAPTKDEVIKQTFAQEGRPDTVRE  69
            A ++W++AD+LRG +K  +YG++ILP T+++R++  L  T+D V+K +   ++  D +RE
Sbjct  18   ANLIWNVADILRGLYKPHEYGKVILPMTVIKRLHDTLLKTRDKVLKTAENTQSINDVMRE  77

Query  70   MILLRAAGQQFFNASPLTLGTL--SDTQTAADLMSYVQAFSKDAREIFEHFHFEDFVQQL  127
             +L  A+G  F+N+S  T+ TL    ++  +++ +Y+++FS + ++I+++F F+  +  +
Sbjct  78   RLLKNASGYSFYNTSLYTFETLLADPANIESNFRAYLNGFSENMQDILNNFKFDVEITTM  137

Query  128  ETANLLYQVVQRFAATD--LSPERISNFGMGIIFEELIRKFAESSNETAGEHFTPRDIVH  185
               ++L+ V+Q F  +D  L+P+++++ +MG +FEEL+RKF+ES NE AG HFT+RDI+ 
Sbjct  138  ADNDVLFYVIQEFNKADAYLGPDKMTSTDMGYVFEELVRKFSESYNEEAGAHFTSRDIIY  197

Query  186  LTTSLVITGQDGKLAPNSIV-TIYDPTAGTGGFLSEGDEYIQSISEKVTVSLHGQELNPE  244
            L T L++  + + L  + +  T+YD T GT+  LS   E I+ +++   V+  GQELNPE
Sbjct  198  LMTDLLLIEDKDTLFKEHVFKTVYDQTMGTSQMLSAMTERIHDMNDTAEVATFGQELNPE  257

Query  245  SYAICKADMLIKGQDVASIKLGNTLSNDQLADKRFDFMLSNPPFGVEWKKVQKQITDEHS  304
            +YAI KAD +I+G D  ++ LG+TL++D++ +  FD+ +SNPPFGV+WKK QK +  EH 
Sbjct  258  TYAISKADTMIRGGDPENMALGSTLTSDRFEGFTFDYCISNPPFGVDWKKDQKAVKAEHE  317

Query  305  HKGFDGRFGPGLPRVSDGSLLFLLHLVSKMRDPRDGGSRIGIILNGSPLFTGGAGSGESE  364
               + GRFG GLPRVSDG LLF L+ +SK+++     +R++II NGS+LF+G +G+GES 
Sbjct  318  LGEL-GRFGVGLPRVSDGQLLFQLNGISKLKET----GRMAIIHNGSALFSGNPGAGESL  372

Query  365  IRRYLLQNDLVEAIIALPTDMFYNTGIATYVWVLSNHKAAVRQGKVQLIDGSQHFAKMRK  424
            IR+Y+++ND +E+II LP D+FYNTGI+TY+W+++++K++ RQGKVQL+D+S+ + K RK
Sbjct  373  IRQYVIENDWLEGIIQLPNDLFYNTGISTYIWIITKDKSPERQGKVQLVDASNMYEKRRK  432

Query  425  SLGSKRQYLTEEQIDELVRLYGRFEE--------TPQSKIFPVEAFGYRRITVERPLR  474
            ++G KR  ++E   + +V+ YG F++        T +SKI+  E+FG+ R+T+ERP R
Sbjct  433  NIGEKRVDISEACREMIVQAYGEFNDKEYYLGDGTVESKILKNESFGFTRVTIERPQR  490


 Score = 66.8 bits (234),  Expect = 4e-12, Method: Compositional matrix adjust.
 Identities = 40/109 (37%), Positives = 62/109 (57%), Gaps = 9/109 (8%)

Query  551  SERDSDADI-CMVKGQPEADAGLRDNENVPLGESVYDYFEREVKPHVPDAWIDESKTDAQ  609
            ++RD ++DI    +G    D+ LRD E++PL E + +YFERE+ P   DAW+D  K    
Sbjct  488  PQRDENGDIVYKKNGSKSVDTNLRDTEDIPLTEDINEYFEREILPFNQDAWMDRKKDK--  545

Query  610  DGEVGVVGFEIPFNRHFYVFQPPRLLEEIDRDLKACTDRIKQMIEGLSA  658
                  +G+EIPF R FY + PP   E I   +K   + I + +++LS+
Sbjct  546  ------IGYEIPFTRLFYKYTPPEPSEVISERIKQLEESIIKNFQALSG  588

76) hsdM2 in NC_014408


> NC_002953_R1|4|G3|49484939|YP_042160.1|Staphylococcus_aureus_subsp._aureus_MSSA476|-|4742..6529|-|SAS0027|type 
I restriction 
enzyme methylase
Length=595

 Score =  350 bits (1313),  Expect = 2e-97, Method: Compositional matrix adjust.
 Identities = 214/482 (45%), Positives = 343/482 (72%), Gaps = 16/482 (3%)

Query  5    QDIVSFIWDIADLLRDTYKRNEYQKVILPFTVLKRFDCVLEHSKDDVLRKYNEYKDKIEN  64
            Q   ++IW++AD+LR+ YK +EY KVILP TV+KR++  L  ++D VL+      ++ ++
Sbjct  15   QKQANLIWNVADILRGLYKPHEYGKVILPMTVIKRLHDTLLKTRDKVLKT----AENTQS  70

Query  65   LDPILEAAAVDKDGRKLGFYNYSKYDFKSLLEDPDHIEENLMHYLDCFSPNVKDIFENFY  124
            ++ ++    + K++   +FYN S Y F +LL DP +IE N+  YL+ FS N++DI++NF 
Sbjct  71   INDVMRERLL-KNASGYSFYNTSLYTFETLLADPANIESNFRAYLNGFSENMQDILNNFK  129

Query  125  IKTHIEKLSKANLLYLLIKKFSESKVDLHPDKISNHDMGIIFEELIRRFSEQSNEEAGQH  184
            +  +I  ++  ++L+ +I+ F+ +   L PDK+++ DMG +FEEL+R+FSE  NEEAG H
Sbjct  130  FDVEITTMADNDVLFYVIQEFNKADAYLGPDKMTSTDMGYVFEELVRKFSESYNEEAGAH  189

Query  185  FTPRDVVKLMTHLLFLENGENLKEKNLIKKIYDPACGTGGMLTSCKNFVREINDTIDVVL  244
            FT+RD++ LMT+LL++E+ + L   +++K +YD + GT+ ML++  + ++++NDT +V  
Sbjct  190  FTSRDIIYLMTDLLLIEDKDTLFKEHVFKTVYDQTMGTSQMLSAMTERIHDMNDTAEVAT  249

Query  245  YGQEINEEIYAICKADMLIKGERAENIKGPSSTLSDDQLKDEKFDFMISNPPYGRKWEQD  304
            +GQE+N E YAI KAD +I+G  +EN+ + +STL+ D++ +  FD+ ISNPP+G  W +D
Sbjct  250  FGQELNPETYAISKADTMIRGGDPENM-ALGSTLTSDRFEGFTFDYCISNPPFGVDWKKD  308

Query  305  KEVVEKEAELGFDGRFGAGLPGIKDGQLLFIQHMLSKMKDDEKSRIAVITNGSPLFTGDA  364
            +  V  E ELG  GRFG GLP + DGQLLF  + +SK+K  E +R+A+I NGS+LF+G++
Sbjct  309  QKAVKAEHELGELGRFGVGLPRVSDGQLLFQLNGISKLK--ETGRMAIIHNGSALFSGNP  366

Query  365  GSGESNIRRWIIENDYLETIIGLPDQLFYNTSIRTYIWILTNQKSPDRIGKIQLIDASSK  424
            G+GES IR+ +IEND LE II LP++LFYNT+I TYIWI+T++KSP+R GK+QL+DAS+ 
Sbjct  367  GAGESLIRQYVIENDWLEGIIQLPNDLFYNTGISTYIWIITKDKSPERQGKVQLVDASNM  426

Query  425  YVKMRKSLGKKRHQLSDRDIDDILTFYRNFSEND--------MVKIFDNDDFGYVKVTVE  476
            Y K RK++G KR ++S+   + I+  Y +F++++          KI+ N+ FG+ +VT+E
Sbjct  427  YEKRRKNIGEKRVDISEACREMIVQAYGEFNDKEYYLGDGTVESKILKNESFGFTRVTIE  486

Query  477  RP  478
            RP
Sbjct  487  RP  488


 Score = 93.1 bits (334),  Expect = 6e-20, Method: Compositional matrix adjust.
 Identities = 53/98 (55%), Positives = 69/98 (71%), Gaps = 1/98 (1%)

Query  560  AFIRNIIHALSEHDETADYVTDTRGNIKPDPKLRDTERIPLKEDIDEYFKREVLPYYPDA  619
            +F R  I+  +++DE +D V    G+   D +LRDTE IPL EDI+EYF RE+LP+  DA
Sbjct  479  GFTRVTIER-PQRDENGDIVYKKNGSKSVDTNLRDTEDIPLTEDINEYFEREILPFNQDA  537

Query  620  WMDRKKDKIGYEINFNQYFYKYKPPRSLEDINSDIQKL  657
            WMDRKKDKIGYEI F + FYKY PP + E I+  I++L
Sbjct  538  WMDRKKDKIGYEIPFTRLFYKYTPPEPSEVISERIKQL  575

77) Psest_3405 in NC_019936


> NC_002953_R1|4|G3|49484939|YP_042160.1|Staphylococcus_aureus_subsp._aureus_MSSA476|-|4742..6529|-|SAS0027|type 
I restriction 
enzyme methylase
Length=595

 Score =  350 bits (1313),  Expect = 2e-97, Method: Compositional matrix adjust.
 Identities = 205/478 (43%), Positives = 338/478 (71%), Gaps = 18/478 (3%)

Query  10   AAFLWSIADLLRGDFKQSQYGRIILPFTLLRRMECVLAPTKDEVIKQTFAQEGRPDTVRE  69
            A ++W++AD+LRG +K  +YG++ILP T+++R++  L  T+D V+K +   ++  D +RE
Sbjct  18   ANLIWNVADILRGLYKPHEYGKVILPMTVIKRLHDTLLKTRDKVLKTAENTQSINDVMRE  77

Query  70   MILLRAAGQQFFNASPLTLGTL--SDTQTAADLMSYVQAFSKDAREIFEHFHFEDFVQQL  127
             +L  A+G  F+N+S  T+ TL    ++  +++ +Y+++FS + ++I+++F F+  +  +
Sbjct  78   RLLKNASGYSFYNTSLYTFETLLADPANIESNFRAYLNGFSENMQDILNNFKFDVEITTM  137

Query  128  ETANLLYQVVQRFAATD--LSPEFISNFGMGIIFEELIRKFAESSNETAGEHFTPRDIVH  185
               ++L+ V+Q F  +D  L+P+ +++ +MG +FEEL+RKF+ES NE AG HFT+RDI+ 
Sbjct  138  ADNDVLFYVIQEFNKADAYLGPDKMTSTDMGYVFEELVRKFSESYNEEAGAHFTSRDIIY  197

Query  186  LTTSLVITNQDHKL-TPNSIVTIYDPTAGTGGFLSEGDEYIQSISEKVSVSLHGQELNPE  244
            L T L++ ++ + L   + + T+YD T GT+  LS   E I+ +++   V+  GQELNPE
Sbjct  198  LMTDLLLIEDKDTLFKEHVFKTVYDQTMGTSQMLSAMTERIHDMNDTAEVATFGQELNPE  257

Query  245  SYAICKADMLIKGQDVASIKLGNTLSNDQLADKRFDFMLSNPPFGVEWKKVQKQITDEHS  304
            +YAI KAD +I+G D  ++ LG+TL++D++ +  FD+ +SNPPFGV+WKK QK +  EH 
Sbjct  258  TYAISKADTMIRGGDPENMALGSTLTSDRFEGFTFDYCISNPPFGVDWKKDQKAVKAEHE  317

Query  305  HKGFDGRFGPGLPRVSDGSLLFLLHLVSKMRDPRDGGSRIGIILNGSPLFTGGAGSGESE  364
               + GRFG GLPRVSDG LLF L+ +SK+++     +R++II NGS+LF+G +G+GES 
Sbjct  318  LGEL-GRFGVGLPRVSDGQLLFQLNGISKLKET----GRMAIIHNGSALFSGNPGAGESL  372

Query  365  IRRYLLQNDLVEAIVALPTDMFYNTGIATYVWILSNHKAAARQGKVQLIDGSQHYAKMRK  424
            IR+Y+++ND +E+I+ LP D+FYNTGI+TY+WI++++K++ RQGKVQL+D+S+ Y K RK
Sbjct  373  IRQYVIENDWLEGIIQLPNDLFYNTGISTYIWIITKDKSPERQGKVQLVDASNMYEKRRK  432

Query  425  SLGSKRQYITEDQISELVRLYGSFEQ--------TAQSKIFPIEAFGYRRITVERPLR  474
            ++G KR  I+E     +V+ YG F++        T +SKI+  E+FG+ R+T+ERP R
Sbjct  433  NIGEKRVDISEACREMIVQAYGEFNDKEYYLGDGTVESKILKNESFGFTRVTIERPQR  490


 Score = 72.3 bits (255),  Expect = 1e-13, Method: Compositional matrix adjust.
 Identities = 39/109 (36%), Positives = 63/109 (58%), Gaps = 9/109 (8%)

Query  551  SERDPEADI-CMTKGQPEADAGLRDNENVPLGESVYDYFQREVIPHVPDAWIDESKTDAQ  609
            ++RD ++DI    +G    D+ LRD E++PL E + +YF+RE++P   DAW+D  K    
Sbjct  488  PQRDENGDIVYKKNGSKSVDTNLRDTEDIPLTEDINEYFEREILPFNQDAWMDRKKDK--  545

Query  610  DGEVGIVGFEIPFNRHFYVFQPPRPLAEIDSDLKACTDRIKQMIEGLSA  658
                  +G+EIPF R FY + PP P   I   +K   + I + +++LS+
Sbjct  546  ------IGYEIPFTRLFYKYTPPEPSEVISERIKQLEESIIKNFQALSG  588

78) Msil_1550 in NC_011666


> NC_002953_R1|4|G3|49484939|YP_042160.1|Staphylococcus_aureus_subsp._aureus_MSSA476|-|4742..6529|-|SAS0027|type 
I restriction 
enzyme methylase
Length=595

 Score =  349 bits (1312),  Expect = 3e-97, Method: Compositional matrix adjust.
 Identities = 219/495 (45%), Positives = 345/495 (70%), Gaps = 23/495 (4%)

Query  1    MRIEKTSNLGSFVWSIAEILRGDFKQSDYGKVILPFIVMRRLDCILEATKPYVLEAAKSL  60
            + ++K +NL   +W++A+ILRG +K  +YGKVILP  V++RL+  L  T+  VL +A + 
Sbjct  12   INVQKQANL---IWNVADILRGLYKPHEYGKVILPMTVIKRLHDTLLKTRDKVLKTAEN-  67

Query  61   PEGIDDETRDMILFGAAGDKIRVYNTSRFTFTSLKGQDPGQVHDNLIDFITGFSPNVRDI  120
             ++I+D  R+ +L  A+G     YNTS +TF +L + DP++++ N+  ++ GFS N++DI
Sbjct  68   TQSINDVMRERLLKNASG--YSFYNTSLYTFETLLA-DPANIESNFRAYLNGFSENMQDI  124

Query  121  FLDKFRFTEALKRLKDGGILWQVFERFCAID--LHPNHVSNIEMGYLFEDLIRRFSEISN  178
             L++F+F   +  + D ++L  V++ F   D  L P+ +++ +MGY+FE+L+R+FSE  N
Sbjct  125  -LNNFKFDVEITTMADNDVLFYVIQEFNKADAYLGPDKMTSTDMGYVFEELVRKFSESYN  183

Query  179  ETAGEHFTPREVIRLIVELLLANDHAALTGTGIIRTVYDPACGTGGMLALTEEAMTALNP  238
            E AG HFT+R++I L+ +LLL +D  +L    +++TVYD + GT+ ML+   E +  +N 
Sbjct  184  EEAGAHFTSRDIIYLMTDLLLIEDKDTLFKEHVFKTVYDQTMGTSQMLSAMTERIHDMND  243

Query  239  KVRVELFGQELNGESFGICKSDMLVTGHNPEQIAFGNTLTEDAHLGKTFHYMLSNPPYGV  298
               V  FGQELN E+++I K+D ++ G +PE++A+G+TLT D   G TF+Y +SNPP+GV
Sbjct  244  TAEVATFGQELNPETYAISKADTMIRGGDPENMALGSTLTSDRFEGFTFDYCISNPPFGV  303

Query  299  DWKKYQDPIRAEHETKGFDGRFGPGLPRISDGQLLFLLHMISKMRDDEQGSRIGIVMNGS  358
            DWKK Q +++AEHE   + GRFG GLPR+SDGQLLF L+ ISK+++    +R++I+ NGS
Sbjct  304  DWKKDQKAVKAEHELGEL-GRFGVGLPRVSDGQLLFQLNGISKLKE---TGRMAIIHNGS  359

Query  359  PLFTGGAGSGESEIRRWMLEKDWVEAIVAMPTDLFYNTGISTYVWLLNNRKPSARRGKVQ  418
            +LF+G +G+GES IR+ ++E+DW+E+I+ +P DLFYNTGISTY+W++ + K++ R+GKVQ
Sbjct  360  ALFSGNPGAGESLIRQYVIENDWLEGIIQLPNDLFYNTGISTYIWIITKDKSPERQGKVQ  419

Query  419  LIDASSERFWKSMRKSLGSKRREIPEAARHEIVRIYAEMLN-----GDGPYGEFSKIVDR  473
            L+DAS+       RK++G KR +I+EA R+ IV+ Y+E  +     GDG     SKI+  
Sbjct  420  LVDASN--MYEKRRKNIGEKRVDISEACREMIVQAYGEFNDKEYYLGDGTVE--SKILKN  475

Query  474  EDFGYREIRIERPLR  488
            E FG+  + IERP R
Sbjct  476  ESFGFTRVTIERPQR  490


 Score = 72.1 bits (254),  Expect = 1e-13, Method: Compositional matrix adjust.
 Identities = 42/100 (42%), Positives = 59/100 (59%), Gaps = 8/100 (8%)

Query  565  SERDESADICLDANGKPESDTQLRDHELVPLNDDWRDFVAREVTPFVPDAWVDENYRDDR  624
            ++RDE++DI    NG    DT+LRD E +PL +D  ++  RE+ PF  DAW+D +     
Sbjct  488  PQRDENGDIVYKKNGSKSVDTNLRDTEDIPLTEDINEYFEREILPFNQDAWMDRK-----  542

Query  625  DGETGRVAYEINFNRYFYKYVPPRPLAQIDCELKQLEAEI  664
                ++++YEI F R FYKY PP P   I   +KQLE  I
Sbjct  543  ---KDKIGYEIPFTRLFYKYTPPEPSEVISERIKQLEESI  579

79) Bcav_1495 in NC_012669


> NC_002953_R1|4|G3|49484939|YP_042160.1|Staphylococcus_aureus_subsp._aureus_MSSA476|-|4742..6529|-|SAS0027|type 
I restriction 
enzyme methylase
Length=595

 Score =  349 bits (1312),  Expect = 3e-97, Method: Compositional matrix adjust.
 Identities = 205/480 (43%), Positives = 337/480 (71%), Gaps = 13/480 (2%)

Query  5    SSFVWSIADLLRGPFKPHQYGTVVLPFTILRRLEGVMAPHREAMVTAVAKAD--DATMRR  62
            ++++W++AD+LRG +KPH+YG V+LP T+++RL++ +   R+ ++ +  +++  +  MR 
Sbjct  18   ANLIWNVADILRGLYKPHEYGKVILPMTVIKRLHDTLLKTRDKVLKTAENTQSINDVMRE  77

Query  63   ALVRRATGLPFYTTSSYTLATALEDPDNLAANLVDYVNGFSAEV-DVFKHFDFEARIHQL  121
             L++ A+G +FY TS YT+ T L DP N+ +N+  Y+NGFS ++ D++++F F+  I  +
Sbjct  78   RLLKNASGYSFYNTSLYTFETLLADPANIESNFRAYLNGFSENMQDILNNFKFDVEITTM  137

Query  122  DAADRLIPVTQGFARVD--LSTDHVSNAGMGDLFEHLIFKDF-EASNAEAGDFYTPRDAI  178
               D L+ V Q F + D  L+ D +++++MG +FE+L+ + F E+ N EAG  +T+RD I
Sbjct  138  ADNDVLFYVIQEFNKADAYLGPDKMTSTDMGYVFEELV-RKFSESYNEEAGAHFTSRDII  196

Query  179  RLLVDLVFAEDTSALAAPGITRSVYDPAAGTGGMLSVAEEHLHELNPKANLALFAQEINP  238
             L+ DL++ ED  +L    + ++VYD + GT+ MLS   E++H++N  A++A F+QE+NP
Sbjct  197  YLMTDLLLIEDKDTLFKEHVFKTVYDQTMGTSQMLSAMTERIHDMNDTAEVATFGQELNP  256

Query  239  ASYAIAKSDMLIKGQNIENVRLGDTLAEDLFDGETFDFALSNPPYGVDWKAAEKAVRAEH  298
             +YAI+K+D +I+G + EN+ LG TL+ D F+G TFD+ +SNPP+GVDWK  +KAV+AEH
Sbjct  257  ETYAISKADTMIRGGDPENMALGSTLTSDRFEGFTFDYCISNPPFGVDWKKDQKAVKAEH  316

Query  299  VRGTGGRFAPGLPSVGDGSMLFLLHLVAKMRPVDArgnggrggIVLNGSPLFNGGAGSGP  358
              G  GRF+ GLP V+DG +LF L+ ++K++  +      R +I+ NGS+LF+G +G+G 
Sbjct  317  ELGELGRFGVGLPRVSDGQLLFQLNGISKLKETG------RMAIIHNGSALFSGNPGAGE  370

Query  359  SEIRGHLLEHDLVDAIVALPNDMFYNTGIATYLWILDNSKQPERRRKVQLIDATKLGTKM  418
            S IR  ++E+D +++I+ LPND+FYNTGI+TY+WI+ + K PER+ KVQL+DA+++  K 
Sbjct  371  SLIRQYVIENDWLEGIIQLPNDLFYNTGISTYIWIITKDKSPERQGKVQLVDASNMYEKR  430

Query  419  RKSLGSKRVEISTADRGRIVQAYDRFDGVAADGDASGPRSKVFDTLDFAYWSVTVERPLR  478
            RK++G KRV+IS A R  IVQAY+ F++     + +   SK++    F++  VT+ERP R
Sbjct  431  RKNIGEKRVDISEACREMIVQAYGEFNDKEYYLGDGTVESKILKNESFGFTRVTIERPQR  490


 Score = 71.0 bits (250),  Expect = 3e-13, Method: Compositional matrix adjust.
 Identities = 44/117 (38%), Positives = 67/117 (58%), Gaps = 17/117 (14%)

Query  550  ERDETADTCTDSKGRPEPDTGLRDTEIVPFGWSDHPKADDAERDTIQAYFDAEVAPHVPD  609
            +RDE +D     +G    DT LRDTE +P+             + I+ YF+ E+ P   D
Sbjct  489  QRDENGDIVYKKNGSKSVDTNLRDTEDIPLT------------EDINEYFEREILPFNQD  536

Query  610  AWIDWTKTRVGYEIPFTRHFYEYVPPRP---LAEIDADLEASVSRILDLL--REVEA  661
            AW+D+ K ++GYEIPFTR FY Y PP P   ++E   +LE S+ + ++ L  +EV++
Sbjct  537  AWMDRKKDKIGYEIPFTRLFYKYTPPEPSEVISERIKQLEESIIKNFQALSGKEVDT  593

80) K734_03215 in NC_021286


> NC_002953_R1|4|G3|49484939|YP_042160.1|Staphylococcus_aureus_subsp._aureus_MSSA476|-|4742..6529|-|SAS0027|type 
I restriction 
enzyme methylase
Length=595

 Score =  349 bits (1312),  Expect = 3e-97, Method: Compositional matrix adjust.
 Identities = 215/515 (42%), Positives = 360/515 (70%), Gaps = 21/515 (4%)

Query  10   ASFIWSVADLLRGHFKQSQYGRVILPFTLLRRLECVLAPNKQKVLEAAKQHQNKPDAVRE  69
            A++IW+VAD+LRG +K  +YG+VILP T+++RL+  L   ++KVL +A + Q+  D +RE
Sbjct  18   ANLIWNVADILRGLYKPHEYGKVILPMTVIKRLHDTLLKTRDKVLKTAENTQSINDVMRE  77

Query  70   QLLLRESQNDFYNASSLTLATL--SDTQTAEDLISYVQSFSSSAREIFEHFNFEEFVLKL  127
            +LL   S   FYN+S  T+ TL    ++   ++ +Y+++FS + ++I+++F+F+  +  +
Sbjct  78   RLLKNASGYSFYNTSLYTFETLLADPANIESNFRAYLNGFSENMQDILNNFKFDVEITTM  137

Query  128  AEADLLYQITQQFGSKID-LSTDNISNYGMGLIFEELIRKFAESSNETAGEHFTPRDCVH  186
            A+ D+L+ + Q+F      L+ D++++ +MG +FEEL+RKF+ES NE AG HFT+RD + 
Sbjct  138  ADNDVLFYVIQEFNKADAYLGPDKMTSTDMGYVFEELVRKFSESYNEEAGAHFTSRDIIY  197

Query  187  AATSLLMTGQEEVLSPNSII-TIYDPTAGTGGFLseseeyiqsiseKVTVKLFGQELNSE  245
              T LL+  + + L  + ++ T+YD T GT+  LS   E I+ +++   V  FGQELN+E
Sbjct  198  LMTDLLLIEDKDTLFKEHVFKTVYDQTMGTSQMLSAMTERIHDMNDTAEVATFGQELNPE  257

Query  246  SYAICKADMMIKSQEVDNIKLGNTLSNDQLAHEKFKYMLANPPFGVDWKASQRVVNDEHK  305
            +YAI KAD MI++ + +N+ LG+TL++D++    F Y ++NPPFGVDWK  Q+ V+ EH 
Sbjct  258  TYAISKADTMIRGGDPENMALGSTLTSDRFEGFTFDYCISNPPFGVDWKKDQKAVKAEHE  317

Query  306  VKGFDGRFGPGLPRVSDGSLLFLLHLVSKMRDTRNGGSRIGIILNGSPLFTGSAGSGESE  365
            +  + GRFG GLPRVSDG LLF L+ +SK+++T    +R++II NGS+LF+G++G+GES 
Sbjct  318  LGEL-GRFGVGLPRVSDGQLLFQLNGISKLKET----GRMAIIHNGSALFSGNPGAGESL  372

Query  366  IRRYLLQNDLVEAIVALPSDMFFNTGISTYIWILSNAKKPERKGKLQLIDGSDAFAKMRK  425
            IR+Y+++ND +E+I+ LP+D+F+NTGISTYIWI+++ K PER+GK+QL+D+S+ + K RK
Sbjct  373  IRQYVIENDWLEGIIQLPNDLFYNTGISTYIWIITKDKSPERQGKVQLVDASNMYEKRRK  432

Query  426  SLGSKRKYLTEENINELVRLYGAVEE--------TKNSKVFPNEAFGYRRVTIERPLRLN  477
            ++G KR  ++E   + +V+ YG  ++        T +SK++ NE+FG+ RVTIERP R  
Sbjct  433  NIGEKRVDISEACREMIVQAYGEFNDKEYYLGDGTVESKILKNESFGFTRVTIERPQR--  490

Query  478  FQASEERVARLDDEKALQ-KLKAEDFSQLKQAIQQ  511
             + + + V + ++ K+++ +L+  +   L + I++
Sbjct  491  -DENGDIVYKKNGSKSVDTNLRDTEDIPLTEDINE  524


 Score = 77.1 bits (273),  Expect = 4e-15, Method: Compositional matrix adjust.
 Identities = 44/109 (41%), Positives = 68/109 (63%), Gaps = 8/109 (7%)

Query  552  SERDSDADVCADKKGNPEADSGLRDYENVPLTDDIYEYFERDVKPHVPDAWIDESKRDEQ  611
            ++RD ++D+   K+G+   D+ LRD E++PLT+DI EYFER++ P   DAW+D  K    
Sbjct  488  PQRDENGDIVYKKNGSKSVDTNLRDTEDIPLTEDINEYFEREILPFNQDAWMDRKK----  543

Query  612  DGEIGIVGFEIPFNRHFYVFEPPRPLEEIDADLKQCTDKIKQMIEELSA  660
                + +G+EIPF R FY + PP P E I   +KQ  + I + ++ LS+
Sbjct  544  ----DKIGYEIPFTRLFYKYTPPEPSEVISERIKQLEESIIKNFQALSG  588

81) hsdM in NC_006512


> NC_002953_R1|4|G3|49484939|YP_042160.1|Staphylococcus_aureus_subsp._aureus_MSSA476|-|4742..6529|-|SAS0027|type 
I restriction 
enzyme methylase
Length=595

 Score =  349 bits (1312),  Expect = 3e-97, Method: Compositional matrix adjust.
 Identities = 215/515 (42%), Positives = 360/515 (70%), Gaps = 21/515 (4%)

Query  10   ASFIWSVADLLRGHFKQSQYGRVILPFTLLRRLECVLAPNKQKVLEAAKQHQNKPDAVRE  69
            A++IW+VAD+LRG +K  +YG+VILP T+++RL+  L   ++KVL +A + Q+  D +RE
Sbjct  18   ANLIWNVADILRGLYKPHEYGKVILPMTVIKRLHDTLLKTRDKVLKTAENTQSINDVMRE  77

Query  70   QLLLRESQNDFYNASSLTLATL--SDTQTAEDLISYVQSFSSSAREIFEHFNFEEFVLKL  127
            +LL   S   FYN+S  T+ TL    ++   ++ +Y+++FS + ++I+++F+F+  +  +
Sbjct  78   RLLKNASGYSFYNTSLYTFETLLADPANIESNFRAYLNGFSENMQDILNNFKFDVEITTM  137

Query  128  AEADLLYQITQQFGSKID-LSTDNISNYGMGLIFEELIRKFAESSNETAGEHFTPRDCVH  186
            A+ D+L+ + Q+F      L+ D++++ +MG +FEEL+RKF+ES NE AG HFT+RD + 
Sbjct  138  ADNDVLFYVIQEFNKADAYLGPDKMTSTDMGYVFEELVRKFSESYNEEAGAHFTSRDIIY  197

Query  187  AATSLLMTGQEEVLSPNSII-TIYDPTAGTGGFLseseeyiqsiseKVTVKLFGQELNSE  245
              T LL+  + + L  + ++ T+YD T GT+  LS   E I+ +++   V  FGQELN+E
Sbjct  198  LMTDLLLIEDKDTLFKEHVFKTVYDQTMGTSQMLSAMTERIHDMNDTAEVATFGQELNPE  257

Query  246  SYAICKADMMIKSQEVDNIKLGNTLSNDQLAHEKFKYMLANPPFGVDWKASQRVVNDEHK  305
            +YAI KAD MI++ + +N+ LG+TL++D++    F Y ++NPPFGVDWK  Q+ V+ EH 
Sbjct  258  TYAISKADTMIRGGDPENMALGSTLTSDRFEGFTFDYCISNPPFGVDWKKDQKAVKAEHE  317

Query  306  VKGFDGRFGPGLPRVSDGSLLFLLHLVSKMRDTRNGGSRIGIILNGSPLFTGSAGSGESE  365
            +  + GRFG GLPRVSDG LLF L+ +SK+++T    +R++II NGS+LF+G++G+GES 
Sbjct  318  LGEL-GRFGVGLPRVSDGQLLFQLNGISKLKET----GRMAIIHNGSALFSGNPGAGESL  372

Query  366  IRRYLLQNDLVEAIVALPSDMFFNTGISTYIWILSNAKKPERKGKLQLIDGSDAFAKMRK  425
            IR+Y+++ND +E+I+ LP+D+F+NTGISTYIWI+++ K PER+GK+QL+D+S+ + K RK
Sbjct  373  IRQYVIENDWLEGIIQLPNDLFYNTGISTYIWIITKDKSPERQGKVQLVDASNMYEKRRK  432

Query  426  SLGSKRKYLTEENINELVRLYGAVEE--------TKNSKVFPNEAFGYRRVTIERPLRLN  477
            ++G KR  ++E   + +V+ YG  ++        T +SK++ NE+FG+ RVTIERP R  
Sbjct  433  NIGEKRVDISEACREMIVQAYGEFNDKEYYLGDGTVESKILKNESFGFTRVTIERPQR--  490

Query  478  FQASEERVARLDDEKALQ-KLKAEDFSQLKQAIQQ  511
             + + + V + ++ K+++ +L+  +   L + I++
Sbjct  491  -DENGDIVYKKNGSKSVDTNLRDTEDIPLTEDINE  524


 Score = 77.1 bits (273),  Expect = 4e-15, Method: Compositional matrix adjust.
 Identities = 44/109 (41%), Positives = 68/109 (63%), Gaps = 8/109 (7%)

Query  552  SERDSDADVCADKKGNPEADSGLRDYENVPLTDDIYEYFERDVKPHVPDAWIDESKRDEQ  611
            ++RD ++D+   K+G+   D+ LRD E++PLT+DI EYFER++ P   DAW+D  K    
Sbjct  488  PQRDENGDIVYKKNGSKSVDTNLRDTEDIPLTEDINEYFEREILPFNQDAWMDRKK----  543

Query  612  DGEIGIVGFEIPFNRHFYVFEPPRPLEEIDADLKQCTDKIKQMIEELSA  660
                + +G+EIPF R FY + PP P E I   +KQ  + I + ++ LS+
Sbjct  544  ----DKIGYEIPFTRLFYKYTPPEPSEVISERIKQLEESIIKNFQALSG  588

82) Nwat_0430 in NC_014315


> NC_002953_R1|4|G3|49484939|YP_042160.1|Staphylococcus_aureus_subsp._aureus_MSSA476|-|4742..6529|-|SAS0027|type 
I restriction 
enzyme methylase
Length=595

 Score =  348 bits (1306),  Expect = 8e-97, Method: Compositional matrix adjust.
 Identities = 208/515 (41%), Positives = 354/515 (69%), Gaps = 27/515 (5%)

Query  11   AAFLWSIADLLRGDFKQSQYGRIILPFTLLRRMECVLEPTKAKVVQQATVHQHKPDHVRE  70
            A ++W++AD+LRG +K  +YG++ILP T+++R++  L  T+ KV++ A   Q   D +RE
Sbjct  18   ANLIWNVADILRGLYKPHEYGKVILPMTVIKRLHDTLLKTRDKVLKTAENTQSINDVMRE  77

Query  71   MLLRRAASGLQFFNASPLTLGTL--SDTQTAADLMSYAQSFSTDACEIFEHFEFENFVQQ  128
             LL+  ASG  F+N+S  T+ TL    ++  +++ +Y ++FS +  +I+++F F+  +  
Sbjct  78   RLLK-NASGYSFYNTSLYTFETLLADPANIESNFRAYLNGFSENMQDILNNFKFDVEITT  136

Query  129  LSSANLLYQVVQRFAATD--LSPARISNFGMGIIFEELIRRFAESSNETAGEHFTPRDIV  186
            ++  ++L+ V+Q F  +D  L+P ++++ +MG +FEEL+R+F+ES NE AG HFT+RDI+
Sbjct  137  MADNDVLFYVIQEFNKADAYLGPDKMTSTDMGYVFEELVRKFSESYNEEAGAHFTSRDII  196

Query  187  HLTTSLVITGQDDKLAPNRIV-TIYDPTAGTGGFLSEGDEYIQSISEKVSVSLHGQELNP  245
             L T L++  + D L  +++  T+YD T GT+  LS   E I+ +++   V+  GQELNP
Sbjct  197  YLMTDLLLIEDKDTLFKEHVFKTVYDQTMGTSQMLSAMTERIHDMNDTAEVATFGQELNP  256

Query  246  ESYAICKADMLIKGQDVANIKLGNTLSNDQLTGPEHRFDFMLSNPPFGVEWKKVQKQISG  305
            E+YAI KAD +I+G D  N+ LG+TL++D++ G    FD+ +SNPPFGV+WKK QK + +
Sbjct  257  ETYAISKADTMIRGGDPENMALGSTLTSDRFEG--FTFDYCISNPPFGVDWKKDQKAVKA  314

Query  306  EHKHKGFNGRFGPGLPRVPDGSLLFLLHLVSKMRDPRDGGSRIGIILNGSPLFTGGAGSG  365
            EH    + GRFG GLPRV+DG LLF L+ +SK+++     +R++II NGS+LF+G +G+G
Sbjct  315  EHELGEL-GRFGVGLPRVSDGQLLFQLNGISKLKET----GRMAIIHNGSALFSGNPGAG  369

Query  366  ESEIRRYLLQHDLVEAIIALPTDMFYNTGIATYVWLLSNHKPAERRGKVQLIDGSQHFAK  425
            ES IR+Y++++D +E+II LP D+FYNTGI+TY+W+++++K++ER+GKVQL+D+S+ + K
Sbjct  370  ESLIRQYVIENDWLEGIIQLPNDLFYNTGISTYIWIITKDKSPERQGKVQLVDASNMYEK  429

Query  426  MRKSLGSKRQYVTAEQINELVRLYGAFEE--------TPQSKIFPINAFGYRRITVERPL  477
             RK++G KR  ++    + +V+ YG F++        T +SKI+  ++FG+ R+T+ERP 
Sbjct  430  RRKNIGEKRVDISEACREMIVQAYGEFNDKEYYLGDGTVESKILKNESFGFTRVTIERPQ  489

Query  478  R-----LNFQASAAR-IDNVLREKAIQKLDDTARQ  506
            R     + ++ ++++ +D  LR+     L +   +
Sbjct  490  RDENGDIVYKKNGSKSVDTNLRDTEDIPLTEDINE  524


 Score = 72.1 bits (254),  Expect = 1e-13, Method: Compositional matrix adjust.
 Identities = 41/108 (38%), Positives = 64/108 (60%), Gaps = 9/108 (8%)

Query  556  ERDPEADI-CTTKGKPEPDTGLRDNENVPLGESVYDYFQREVIPHVPDAWINESKRDALD  614
            +RD ++DI    +G    DT LRD E++PL E + +YF+RE++P   DAW+ + K+D   
Sbjct  489  QRDENGDIVYKKNGSKSVDTNLRDTEDIPLTEDINEYFEREILPFNQDAWM-DRKKDK--  545

Query  615  GEVGIVGFEIPFNRHFYVFQPPRPLEAIDRDLKACTDRIKQMIEELSA  662
                 +G+EIPF R FY + PP P E I   +K   + I + ++ LS+
Sbjct  546  -----IGYEIPFTRLFYKYTPPEPSEVISERIKQLEESIIKNFQALSG  588

83) Tgr7_0604 in NC_011901


> NC_002953_R1|4|G3|49484939|YP_042160.1|Staphylococcus_aureus_subsp._aureus_MSSA476|-|4742..6529|-|SAS0027|type 
I restriction 
enzyme methylase
Length=595

 Score =  347 bits (1304),  Expect = 1e-96, Method: Compositional matrix adjust.
 Identities = 208/476 (44%), Positives = 335/476 (71%), Gaps = 18/476 (3%)

Query  9    ASFLWSVADLLRGDFKQSQYGRIILPFTLLRRLECVLAPTKQAVLAEYDKRKDSDLPMGP  68
            A+++W+VAD+LRG +K  +YG++ILP T+++RL+  L  T++ VL   ++ +  +  M  
Sbjct  18   ANLIWNVADILRGLYKPHEYGKVILPMTVIKRLHDTLLKTRDKVLKTAENTQSINDVMRE  77

Query  69   FLEKASGGLKFYNTSPMDLASL--GETQVLDNLDTYIRSFSPAAREIFEHFGFHGFLEKL  126
             L K ++G  FYNTS   + +L  + +++  N+ +Y+ +FS   ++I+++F F+  +  +
Sbjct  78   RLLKNASGYSFYNTSLYTFETLLADPANIESNFRAYLNGFSENMQDILNNFKFDVEITTM  137

Query  127  DEANLLYQVIQRFASTD--LSPQAHSNYEMGLIFEELIRRFAESSNETAGEHFTPRDIVH  184
             + ++L+ VIQ F  +D  L+P+  ++ +MG +FEEL+R+F+ES NE AG HFT+RDI+ 
Sbjct  138  ADNDVLFYVIQEFNKADAYLGPDKMTSTDMGYVFEELVRKFSESYNEEAGAHFTSRDIIY  197

Query  185  LTTALLFTDQQEKIAPGKIV-TVYDPTAGTGGFLSEGEEYIHSISQDARVRVFGQELNPE  243
            L T LL+ ++++ +    +  TVYD T GT+  LS   E IH +++ A V  FGQELNPE
Sbjct  198  LMTDLLLIEDKDTLFKEHVFKTVYDQTMGTSQMLSAMTERIHDMNDTAEVATFGQELNPE  257

Query  244  SHAICMADMLIKGHEIDNIKLGNTLSDDQLPAQQFDFMLSNPPFGVDWKKVQKQVQDEHK  303
            + AI  AD +I+G + +N+ LG+TL+ D++ +  FD+ +SNPPFGVDWKK QK V+ EH 
Sbjct  258  TYAISKADTMIRGGDPENMALGSTLTSDRFEGFTFDYCISNPPFGVDWKKDQKAVKAEHE  317

Query  304  LKGHAGRFGPGLPRVSDGSLLFLMHLMSKMRDAKEQGSRIGIILNGSPLFTGGAGSGESE  363
            L G+ GRFG GLPRVSDG LLF ++ +SK++++    +R++II NGS+LF+G +G+GES 
Sbjct  318  L-GELGRFGVGLPRVSDGQLLFQLNGISKLKET----GRMAIIHNGSALFSGNPGAGESL  372

Query  364  IRRHILENDLLEAIVALPTDMFYNTGIATYVWVLSNHKRPERKGRVQLINATDMGDKMRK  423
            IR+ ++END LE+I+ LP D+FYNTGI+TY+W+++++K PER+G+VQL++A++M +K RK
Sbjct  373  IRQYVIENDWLEGIIQLPNDLFYNTGISTYIWIITKDKSPERQGKVQLVDASNMYEKRRK  432

Query  424  SLGSKRKYLTEDSIETIVRLYGAFEETE--------TSKIFNTTDFGYRRITVERP  471
            ++G KR  ++E   E IV+ YG F++ E         SKI++   FG+ R+T+ERP
Sbjct  433  NIGEKRVDISEACREMIVQAYGEFNDKEYYLGDGTVESKILKNESFGFTRVTIERP  488


 Score = 76.0 bits (269),  Expect = 8e-15, Method: Compositional matrix adjust.
 Identities = 41/108 (38%), Positives = 63/108 (59%), Gaps = 9/108 (8%)

Query  549  EHDDQAE-VCKTKGQPEPNPDLRDNENVPLGEDIHAYFAREVTPHVPDAWIDESKKDEQD  607
            ++D++++ V K +G    + +LRD E++PL EDI+ YF RE+ P   DAW+D  K     
Sbjct  489  QRDENGDIVYKKNGSKSVDTNLRDTEDIPLTEDINEYFEREILPFNQDAWMDRKKDK---  545

Query  608  GQVGIVGYEIPFNRHFYQYVPPRPLEEIDADLDQVSREIMALLQEVHA  655
                 +GYEIPF R FY+Y PP P E I   + Q+   I+  +Q + +
Sbjct  546  -----IGYEIPFTRLFYKYTPPEPSEVISERIKQLEESIIKNFQALSG  588

84) Saut_0167 in NC_014506


> NC_002953_R1|4|G3|49484939|YP_042160.1|Staphylococcus_aureus_subsp._aureus_MSSA476|-|4742..6529|-|SAS0027|type 
I restriction 
enzyme methylase
Length=595

 Score =  346 bits (1299),  Expect = 3e-96, Method: Compositional matrix adjust.
 Identities = 225/479 (47%), Positives = 335/479 (70%), Gaps = 16/479 (3%)

Query  4    QSISALIWSTADLLRGDYKQSDYGKIILPFTLLRRLECVLEPTRDDVLTENEARKNLGIP  63
            Q  + LIW+ AD+LRG YK  +YGK+ILP T+++RL+  L  TRD VL   E  +++   
Sbjct  15   QKQANLIWNVADILRGLYKPHEYGKVILPMTVIKRLHDTLLKTRDKVLKTAENTQSINDV  74

Query  64   M-EQFLTRKSGHSFYNTSKYTLTKLMSDPSNISQNLESYINDFSPNAREIFEKYEFTAQI  122
            M E++L   SG SFYNTS YT+  L++DP+NI  N+ +Y+N+FS N ++I++++ F  +I
Sbjct  75   MRERLLKNASGYSFYNTSLYTFETLLADPANIESNFRAYLNGFSENMQDILNNFKFDVEI  134

Query  123  DKLNEANLLYLIIEKFATVD--LHPDTISNHAMGIVFEELIRKFAEQSNETAGEHFTPRD  180
              + + ++L+ +I+ F   D  L PD +++  MG VFEEL+RKF+E  NE AG HFT+RD
Sbjct  135  TTMADNDVLFYVIQEFNKADAYLGPDKMTSTDMGYVFEELVRKFSESYNEEAGAHFTSRD  194

Query  181  IVRLTTSLLFSTDDDVLTKKGIVRSLYDPTAGTGGFLSSGSEYVHELNPDATLVTFGQEL  240
            I+ L T LL+  D D L K  + +++YD T GT+  LS+ +E +H++N  A + TFGQEL
Sbjct  195  IIYLMTDLLLIEDKDTLFKEHVFKTVYDQTMGTSQMLSAMTERIHDMNDTAEVATFGQEL  254

Query  241  NGESYAICKADMMIKGVQVENIKHGNTLSDDQLGENKFDYMLSNPPFGvewkkvekvvka  300
            N E+YAI KAD MI+G + EN+  G+TL+ D++    FDY +SNPPFGV+WKK +K VKA
Sbjct  255  NPETYAISKADTMIRGGDPENMALGSTLTSDRFEGFTFDYCISNPPFGVDWKKDQKAVKA  314

Query  301  enaeQGYNGRFGPGLPRVSDGSLLFLLHLVSKMRPKREGGSRIGIILNGSPLFTGGAGSG  360
            E+      GRFG GLPRVSDG LLF L+ +SK++      +R++II NGS+LF+G +G+G
Sbjct  315  EHELGEL-GRFGVGLPRVSDGQLLFQLNGISKLK----ETGRMAIIHNGSALFSGNPGAG  369

Query  361  ESEIRRYILENDYLEAIVAMPNDMFFNTGIATYIWILSNNKPEHRQGEVQLINASSMGNA  420
            ES IR+Y++END LE+I+ +PND+F+NTGI+TYIWI++++K+ +RQG VQL++AS+M + 
Sbjct  370  ESLIRQYVIENDWLEGIIQLPNDLFYNTGISTYIWIITKDKSPERQGKVQLVDASNMYEK  429

Query  421  MRKSLGSKRKFLDETQISDIVRIYGE--------NAAAKISKIFNITDFGYRRITVERS  471
             RK++G KR  + E+    IV+ YGE          ++  SKI++   FG+ R+T+ER+
Sbjct  430  RRKNIGEKRVDISEACREMIVQAYGEFNDKEYYLGDGTVESKILKNESFGFTRVTIERP  488


 Score = 73.6 bits (260),  Expect = 4e-14, Method: Compositional matrix adjust.
 Identities = 43/115 (38%), Positives = 68/115 (60%), Gaps = 8/115 (6%)

Query  538  FKLVQKHISMHDDEAELCKDSKGKLEANADLRDYENIPLSEDINEYFAREVTPHVPLAWI  597
            F  V  + + +D+++++    +G    +++LRD E+IPL+EDINEYF RE+ P    AW+
Sbjct  480  FTRVTIERPQRDENGDIVYKKNGSKSVDTNLRDTEDIPLTEDINEYFEREILPFNQDAWM  539

Query  598  DEKKRDAKDGEVGIVGYEIPFNRHFYEYAPPRPLEEIDAELETLNAEIMEMLREI  652
            D KK        + +GYEIPF R FY Y+PP P E I   +  L+  I+  ++ +
Sbjct  540  DRKK--------DKIGYEIPFTRLFYKYTPPEPSEVISERIKQLEESIIKNFQAL  586

85) Noc_2687 in NC_007484


> NC_002953_R1|4|G3|49484939|YP_042160.1|Staphylococcus_aureus_subsp._aureus_MSSA476|-|4742..6529|-|SAS0027|type 
I restriction 
enzyme methylase
Length=595

 Score =  346 bits (1298),  Expect = 3e-96, Method: Compositional matrix adjust.
 Identities = 204/481 (43%), Positives = 339/481 (71%), Gaps = 21/481 (4%)

Query  10   AAFLWSIADLLRGDFKQSQYGRIILPFTLLRRMECVLEPTKDKVVQQATVHQHKPDHVRE  69
            A ++W++AD+LRG +K  +YG++ILP T+++R++  L  T+DKV++ A   Q   D +RE
Sbjct  18   ANLIWNVADILRGLYKPHEYGKVILPMTVIKRLHDTLLKTRDKVLKTAENTQSINDVMRE  77

Query  70   MLLRRAAGDLQFFNASPLTLGTL--SDTQTAADLMSYAQSFSTDACEIFEHFEFENFVQQ  127
             LL+ A+G   F+N+S  T+ TL    ++  +++ +Y ++FS +  +I+++F F+  +  
Sbjct  78   RLLKNASG-YSFYNTSLYTFETLLADPANIESNFRAYLNGFSENMQDILNNFKFDVEITT  136

Query  128  LSSANLLYQVVQRFAATD--LSPARISNFGMGIIFEELIRRFAESSNETAGEHFTPRDIV  185
            ++  ++L+ V+Q F  +D  L+P ++++ +MG +FEEL+R+F+ES NE AG HFT+RDI+
Sbjct  137  MADNDVLFYVIQEFNKADAYLGPDKMTSTDMGYVFEELVRKFSESYNEEAGAHFTSRDII  196

Query  186  HLTTSLVITGQDDKLAPNRIV-TIYDPTAGTGGFLSEGDEYIQSISEKVSVSLHGQELNP  244
             L T L++  + D L  +++  T+YD T GT+  LS   E I+ +++   V+  GQELNP
Sbjct  197  YLMTDLLLIEDKDTLFKEHVFKTVYDQTMGTSQMLSAMTERIHDMNDTAEVATFGQELNP  256

Query  245  ESYAICKADMLIKGQDVANIKLGNTLSNDQLTGPEHRFDFMLSNPPFGVEWKKVQKQITG  304
            E+YAI KAD +I+G D  N+ LG+TL++D++ G    FD+ +SNPPFGV+WKK QK + +
Sbjct  257  ETYAISKADTMIRGGDPENMALGSTLTSDRFEG--FTFDYCISNPPFGVDWKKDQKAVKA  314

Query  305  EHKHKGFNGRFGPGLPRVSDGSLLFLLHLVSKMRDPRDGGSRIGIILNGSPLFTGGAGSG  364
            EH    + GRFG GLPRVSDG LLF L+ +SK+++     +R++II NGS+LF+G +G+G
Sbjct  315  EHELGEL-GRFGVGLPRVSDGQLLFQLNGISKLKET----GRMAIIHNGSALFSGNPGAG  369

Query  365  ESEIRRYLLQHDLVEAIVALPTDMFYNTGIATYVWLLSNHKPAERRGKVQLIDGSQHFAK  424
            ES IR+Y++++D +E+I+ LP D+FYNTGI+TY+W+++++K++ER+GKVQL+D+S+ + K
Sbjct  370  ESLIRQYVIENDWLEGIIQLPNDLFYNTGISTYIWIITKDKSPERQGKVQLVDASNMYEK  429

Query  425  MRKSLGSKRQYVTAEQINELVCLYGAFEE--------TPQSKIFPINAFGYRRITVERPL  476
             RK++G KR  ++    + +V  YG F++        T +SKI+  ++FG+ R+T+ERP 
Sbjct  430  RRKNIGEKRVDISEACREMIVQAYGEFNDKEYYLGDGTVESKILKNESFGFTRVTIERPQ  489

Query  477  R  477
            R
Sbjct  490  R  490


 Score = 70.5 bits (248),  Expect = 3e-13, Method: Compositional matrix adjust.
 Identities = 41/108 (38%), Positives = 64/108 (60%), Gaps = 9/108 (8%)

Query  555  KRDPKADI-CTTKGKPEPDTGLRDNENVPLGESVYDYFQREVIPHVPDAWINESKRDALD  613
            +RD ++DI    +G    DT LRD E++PL E + +YF+RE++P   DAW+ + K+D   
Sbjct  489  QRDENGDIVYKKNGSKSVDTNLRDTEDIPLTEDINEYFEREILPFNQDAWM-DRKKDK--  545

Query  614  GEVGIVGFEIPFNRHFYVFQPPRPLEEIDRDLKACTDRIKQMIEELSA  661
                 +G+EIPF R FY + PP P E I   +K   + I + ++ LS+
Sbjct  546  -----IGYEIPFTRLFYKYTPPEPSEVISERIKQLEESIIKNFQALSG  588

86) Mlab_0841 in NC_008942


> NC_002953_R1|4|G3|49484939|YP_042160.1|Staphylococcus_aureus_subsp._aureus_MSSA476|-|4742..6529|-|SAS0027|type 
I restriction 
enzyme methylase
Length=595

 Score =  346 bits (1299),  Expect = 3e-96, Method: Compositional matrix adjust.
 Identities = 243/605 (41%), Positives = 387/605 (64%), Gaps = 46/605 (7%)

Query  2    NQIHAAQVSKIASFIWNIADDCLRDVYSRGKYRDVILPMTVIRRIDAVLEPTKEKVIAQK  61
            +Q  + +V K A++IWN+AD  LR++Y    Y  VILPMTVI+R++  L  T++KV+   
Sbjct  7    HQQTSINVQKQANLIWNVAD-ILRGLYKPHEYGKVILPMTVIKRLHDTLLKTRDKVLKTA  65

Query  62   KMLDKANIKAQSDALCLASGQAFYNSSPFCLKDLTSRAKPQQLKADFIAYLDGYSPNIQE  121
               +  N   +   L  ASG +FYN+S + +  L   A P ++ ++F AYL+G+S N+Q+
Sbjct  66   ENTQSINDVMRERLLKNASGYSFYNTSLYTFETLL--ADPANIESNFRAYLNGFSENMQD  123

Query  122  ILNKFKFRNQIDTMIEAGILGAVIEKFVSSEINLSMNDILDKQGGVRMPGLDNHMMGTLF  181
            ILN+FKF  +I TM + ++L  VI+ F  ++  L         G  +M + D   MG +F
Sbjct  124  ILNNFKFDVEITTMADNDVLFYVIQEFNKADAYL---------GPDKMTSTD---MGYVF  171

Query  182  EELLRKFNEENNEEAGEHFTPRDVVELMADLVFMPIADKI-EDGTY-LLYDDACGTGGML  239
            EEL+RKF+E  NEEAG HFT+RD++ LM+DL+++   D +  +  +  +YD++ GT+ ML
Sbjct  172  EELVRKFSESYNEEAGAHFTSRDIIYLMTDLLLIEDKDTLFKEHVFKTVYDQTMGTSQML  231

Query  240  TVGEQRLNELAIKYNKKFSVHLFGQETVPETYAICKSDMLLKGKGEQAEHIFYGSTLSND  299
            +   +R++++    N    V  FGQE  PETYAI K+D +++G   ++E++  GSTL++D
Sbjct  232  SAMTERIHDM----NDTAEVATFGQELNPETYAISKADTMIRG--GDPENMALGSTLTSD  285

Query  300  GFAGHEFDFMISNPPYGKSWKTDAEKMGGKKDISD-PRFVVLHKNEELSLIPRVSDGQML  358
             F G  FD+ ISNPP+G  WK D   + +  ++++  RF V         +PRVSDGQ+L
Sbjct  286  RFEGFTFDYCISNPPFGVDWKKDQKAVKAEHELGELGRFGVG--------LPRVSDGQLL  337

Query  359  FLANNVSKMKSKTKLGSRIAEVHNGSSLFTGDAGSGESNFRRYIIENDLVEAIIALPENI  418
            F  N +SK+K      +R+A +HNGS+LF+G++G+GES +R+Y+IEND +E+II LP+++
Sbjct  338  FQLNGISKLKE----TGRMAIIHNGSALFSGNPGAGESLIRQYVIENDWLEGIIQLPNDL  393

Query  419  FYNTGIATYIWVLSNKKSESRRGKVQLIDATSFKTPLRKNLGKKNCEVSFEQKNEIVKLL  478
            FYNTGI+TYIW++++ KS  R+GKVQL+DA++     RKN+G K  ++S   ++ IV+  
Sbjct  394  FYNTGISTYIWIITKDKSPERQGKVQLVDASNMYEKRRKNIGEKRVDISEACREMIVQAY  453

Query  479  IDFKENEF--------SKIFRNEEFLYWSITVERPKVDEAGNVVKDKKGSPKADADLRDV  530
             +F+++E+        SKI++NE F +  +T+ERP+ DE G++V  K+GS   D++LRD 
Sbjct  454  GEFNDKEYYLGDGTVESKILKNESFGFTRVTIERPQRDENGDIVYKKNGSKSVDTNLRDT  513

Query  531  EMVPYVYEGGIEAFMKNEVLPYSPDAWVDDKKTETGCELSFTKYFYKPVELRSLDEIVAD  590
            E +P     +I+ +   E+LP++ DAW+D KK   G E++FT+ FYK     + + I   
Sbjct  514  EDIPLT--EDINEYFEREILPFNQDAWMDRKKDKIGYEIPFTRLFYKYTPPEPSEVISER  571

Query  591  IRALE  595
            I+ LE
Sbjct  572  IKQLE  576

87) PALO_04810 in NC_021064


> NC_002953_R1|4|G3|49484939|YP_042160.1|Staphylococcus_aureus_subsp._aureus_MSSA476|-|4742..6529|-|SAS0027|type 
I restriction 
enzyme methylase
Length=595

 Score =  346 bits (1298),  Expect = 4e-96, Method: Compositional matrix adjust.
 Identities = 208/485 (43%), Positives = 329/485 (68%), Gaps = 19/485 (3%)

Query  7    QDKVAFVWRVADKLRGTFKQHEYGSVMLPLLVLRRMDAVLEPTKDEVLEYADGLVEIGPG  66
            Q +  ++W VAD LRG +K HEYG V+LP+ V++R++  L  T+D VL  A+    I   
Sbjct  15   QKQANLIWNVADILRGLYKPHEYGKVILPMTVIKRLHDTLLKTRDKVLKTAENTQSINDV  74

Query  67   -QDRILKRICGQRFYNTSRYTFARLLSDDKNLADNLAKYIASLSPDAATVIEAYQFDGKI  125
             ++R+LK   G  FYNTS YTF  LL+D  N+  N+  Y+ ++S +   +++ ++FD  I
Sbjct  75   MRERLLKNASGYSFYNTSLYTFETLLADPANIESNFRAYLNGFSENMQDILNNFKFDVEI  134

Query  126  TRMDHAGILYGVMADFADLD--LRPSEVSNETMGYIFEELLRKFSEMSNETAGEHYTPRE  183
            T M + ++L+ V+ +F   D  L P  +++  MGY+FEEL+RKFSE  NE AG H+T+R+
Sbjct  135  TTMADNDVLFYVIQEFNKADAYLGPDKMTSTDMGYVFEELVRKFSESYNEEAGAHFTSRD  194

Query  184  VIRLVADLLIGGQTARDLTENQMPVRTIYDPAAGTGGMLMITMDRIKELNPKALVKVYGQ  243
            +I L++DLL+  +    + E+    +T+YD + GT+ ML    +RI ++N  A V  +GQ
Sbjct  195  IIYLMTDLLLIEDKDTLFKEH--VFKTVYDQTMGTSQMLSAMTERIHDMNDTAEVATFGQ  252

Query  244  ELNDETWAIAQSDLMMQGIGPEQMHNGNTLTADAFPTDKFDFILANPPYGVDWKGYAQPI  303
            ELN ET AI+++D M++G +PE+M  G+TLT+D F    FD+ ++NPP+GVDWK   +++
Sbjct  253  ELNPETYAISKADTMIRGGDPENMALGSTLTSDRFEGFTFDYCISNPPFGVDWKKDQKAV  312

Query  304  KDEHNRQGFNGRFGAGLPRVSDGSLLFLQHMLSHMKPVTDASPNGSRVGIVLSGSPLFSG  363
            K EH+   + GRFG GLPRVSDG LLF  + +S +K       + +R++I+ +GS+LFSG
Sbjct  313  KAEHELGEL-GRFGVGLPRVSDGQLLFQLNGISKLK-------ETGRMAIIHNGSALFSG  364

Query  364  QAGSGESEIRRWLLENDWLEGIVALPDQMFYNTGISTYVWILTNARTDAERGLVKLIDAR  423
            ++G+GES IR+ ++ENDWLEGI+ LP+++FYNTGISTY+WI+T+ ++   +G V+L+DA 
Sbjct  365  NPGAGESLIRQYVIENDWLEGIIQLPNDLFYNTGISTYIWIITKDKSPERQGKVQLVDAS  424

Query  424  DMGTKMRKSLGDKRKELTDDAIDEIVRLFSGALDE---FADDKRV--KVLPRETFGFQRV  478
            +M  K RK++G+KR ++++   + IV+ + G +++   + +D  V  K+L  E+FGF RV
Sbjct  425  NMYEKRRKNIGEKRVDISEACREMIVQAY-GEFNDKEYYLGDGTVESKILKNESFGFTRV  483

Query  479  TVERP  483
            T+ERP
Sbjct  484  TIERP  488


 Score = 61.8 bits (215),  Expect = 2e-10, Method: Compositional matrix adjust.
 Identities = 38/98 (39%), Positives = 54/98 (56%), Gaps = 16/98 (16%)

Query  539  NDPGAPVVMKKGKPEPDTDLRDQENIPLPAGWFdldddaraqalldSAEKHLTEEIRPYL  598
            ++ G  V  K+G    DT+LRD E+IPL  +                 +  +  EI P+ 
Sbjct  491  DENGDIVYKKNGSKSVDTNLRDTEDIPLTED----------------INEYFEREILPFN  534

Query  599  PDAWIDHDKTKLGFEIPFTRQFYVYTPPRPVEEMADEI  636
             DAW+D+ K K+G+EIPFTR FY YTPP P E +++ I
Sbjct  535  QDAWMDRKKDKIGYEIPFTRLFYKYTPPEPSEVISERI  572

88) F750_6067 in NC_021055


> NC_002953_R1|4|G3|49484939|YP_042160.1|Staphylococcus_aureus_subsp._aureus_MSSA476|-|4742..6529|-|SAS0027|type 
I restriction 
enzyme methylase
Length=595

 Score =  345 bits (1297),  Expect = 5e-96, Method: Compositional matrix adjust.
 Identities = 219/500 (44%), Positives = 339/500 (68%), Gaps = 27/500 (5%)

Query  1    MNSSKHTELANHAWSVADLLRGDYKQSDYGKVILPFLVLRRLECVLEPTREKVAETATRF  60
            +N  K+++L    W+VAD+LRG YK  +YGKVILP  V++RL+  L  TR+KV  TA   
Sbjct  12   INVQKQANLI---WNVADILRGLYKPHEYGKVILPMTVIKRLHDTLLKTRDKVLKTAENT  68

Query  61   EG-QEIDTDHFLRRASGHSFYNTSSLTLRKIAGDASNAAANLQVYVGGFSPNAREVMEKY  119
            ++ +++  +++L+ ASG SFYNTS  T+  + +D++N  +N++ Y+ GFS N +++++++
Sbjct  69   QSINDVMRERLLKNASGYSFYNTSLYTFETLLADPANIESNFRAYLNGFSENMQDILNNF  128

Query  120  EFAQQIRKLDSANLLYQVIGKFTDLD--LRPEVVPNHNMGYIFEELIRRFSEQSNETAGE  177
             F  +I  +   ++L+ VI  F   D  L P+ + + +MGY+FEEL+R+FSE  NE AG 
Sbjct  129  KFDVEITTMADNDVLFYVIQEFNKADAYLGPDKMTSTDMGYVFEELVRKFSESYNEEAGA  188

Query  178  HFTPREVIRLMVNLLIAPDGDALSVPGVVRTVMDPACGTGGMLSAAEEHIKSYNDDATVE  237
            HFT+R++I LM +LL+  D D+L    V +TV D + GT+ MLSA  E+I   ND A V 
Sbjct  189  HFTSRDIIYLMTDLLLIEDKDTLFKEHVFKTVYDQTMGTSQMLSAMTERIHDMNDTAEVA  248

Query  238  VYGQELNPESWAICRSDLMIKEQNPENIAFGNSFSDDGHARETFDYLLANPPFGVEWKKV  297
             +GQELNPE+ AI ++D MI+  +PEN+A+G++++ D     TFDY ++NPPFGV+WKK 
Sbjct  249  TFGQELNPETYAISKADTMIRGGDPENMALGSTLTSDRFEGFTFDYCISNPPFGVDWKKD  308

Query  298  KEAVEYEHNNLGDSGRFGAGLPRINDGSLLFLQHMISKMKPVDVHGGGGSRVAIVFNGSP  357
            + AV  EH +LG+ GRFG GLPR++DG LLF  + ISK+K         +R+AI+ NGS+
Sbjct  309  QKAVKAEH-ELGELGRFGVGLPRVSDGQLLFQLNGISKLK-------ETGRMAIIHNGSA  360

Query  358  LFTGAAGSGESEIRRWILENDWLEAIVALPDQLFYNTGISTYFWILTNRKDAQHKGKVVL  417
            LF+G +G+GES IR+ ++ENDWLE+I+ LP++LFYNTGISTY+WI+T+ K ++++GKV L
Sbjct  361  LFSGNPGAGESLIRQYVIENDWLEGIIQLPNDLFYNTGISTYIWIITKDKSPERQGKVQL  420

Query  418  LDARDQWVKMRKSLGDKRKELGDGTGGKPNHIGDITRLYGEAVTAAADAEHPM---HAKV  474
            +DA +   K RK++G+KR +++++          I + YGE      D E  +       
Sbjct  421  VDASNMYEKRRKNIGEKRVDISEACREM------IVQAYGE----FNDKEYYLGDGTVES  470

Query  475  KVFDNTAFGYQRITVERPLK  494
            K++ N +FG+ R+T+ERP +
Sbjct  471  KILKNESFGFTRVTIERPQR  490


 Score = 82.6 bits (294),  Expect = 9e-17, Method: Compositional matrix adjust.
 Identities = 44/90 (49%), Positives = 60/90 (67%), Gaps = 1/90 (1%)

Query  607  RDPEGEMQLLKGAPEP-DGELRDYENVPLGEDIDEYLKREVHPHVPDAWIDHTKTKVGYE  665
            RD +G++   K ++ + D +LRD E++PL EDI+EY+ RE+ P   DAW+D+ K K+GYE
Sbjct  490  RDENGDIVYKKNGSKSVDTNLRDTEDIPLTEDINEYFEREILPFNQDAWMDRKKDKIGYE  549

Query  666  IPFTRHFYVYKPPRPVAEIDAELKALEAEI  695
            IPFTR FY Y PP P   I   +K LE  I
Sbjct  550  IPFTRLFYKYTPPEPSEVISERIKQLEESI  579

89) hsdM in NC_007481


> NC_002953_R1|4|G3|49484939|YP_042160.1|Staphylococcus_aureus_subsp._aureus_MSSA476|-|4742..6529|-|SAS0027|type 
I restriction 
enzyme methylase
Length=595

 Score =  345 bits (1295),  Expect = 6e-96, Method: Compositional matrix adjust.
 Identities = 212/499 (43%), Positives = 344/499 (69%), Gaps = 40/499 (8%)

Query  10   AAFLWSVADLLRGDFKQSQYGRIILPFTLLRRLECVLEATKPAVLEKYEAVKAMPIEAQD  69
            A ++W+VAD+LRG +K  +YG++ILP T+++RL+  L  T+  VL   E  +++    ++
Sbjct  18   ANLIWNVADILRGLYKPHEYGKVILPMTVIKRLHDTLLKTRDKVLKTAENTQSINDVMRE  77

Query  70   KLLTHAAQLSFYNTSKMDLNRL--GETDVASNLESYIQSFSPNAREIFEHFDFFNTIDKL  127
            +LL +A+  SFYNTS   ++ L  + +++ SN+ +Y+++FS N ++I+++F F   I  +
Sbjct  78   RLLKNASGYSFYNTSLYTFETLLADPANIESNFRAYLNGFSENMQDILNNFKFDVEITTM  137

Query  128  AEADLLYKVAKRFATTD--LHPDVINNYGMGLVFEELIRRFAESSNETAGEHFTPRDIVR  185
            A+ D+L+ V + F  +D  L PD + + +MG VFEEL+R+F+ES NE AG HFT+RDI+ 
Sbjct  138  ADNDVLFYVIQEFNKADAYLGPDKMTSTDMGYVFEELVRKFSESYNEEAGAHFTSRDIIY  197

Query  186  LTTSLVFTNDDDALTQSGLVRSIYDPTAGTGGFLSSGMEYVLELNDKASLSAFGQELNPE  245
            L T L++ +D D+L +  + +++YD T GT+  LS+  E + ++ND A +++FGQELNPE
Sbjct  198  LMTDLLLIEDKDTLFKEHVFKTVYDQTMGTSQMLSAMTERIHDMNDTAEVATFGQELNPE  257

Query  246  SYAICKADMLIKGQKVDNIKLGNTLSNDQLRTEKFDYMLSNPPFGVDWKKIQKQINDEHT  305
            +YAI KAD +I+G   +N+ LG+TL++D++    FDY +SNPPFGVDWKK QK ++ EH 
Sbjct  258  TYAISKADTMIRGGDPENMALGSTLTSDRFEGFTFDYCISNPPFGVDWKKDQKAVKAEH-  316

Query  306  DKGFEGRFGAGLPRVSDGSLLFLMHLVSKMRPQHEGGSRIGIILNGSPLFTGGAGSGESE  365
            + G  GRFG GLPRVSDG LLF ++ +SK++      +R++II NGS+LF+G +G+GES 
Sbjct  317  ELGELGRFGVGLPRVSDGQLLFQLNGISKLK----ETGRMAIIHNGSALFSGNPGAGESL  372

Query  366  IRRYILENDLLEAIVALPSDMFYNTGISTYVWVLSTHKPANRKGKVQLINAAKERAKtgg  425
            IR+Y++END LE+I+ LP+D+FYNTGISTY+W+++ +K+++R+GKVQL++A++       
Sbjct  373  IRQYVIENDWLEGIIQLPNDLFYNTGISTYIWIITKDKSPERQGKVQLVDASN-------  425

Query  426  rgrsgggesteEVENVFYAAMRKSLGSKRKELTEDAIDTIVKTYGQFVENDF--------  477
                             Y   RK++G KR +++E   + IV++YG+F ++++        
Sbjct  426  ----------------MYEKRRKNIGEKRVDISEACREMIVQAYGEFNDKEYYLGDGTVE  469

Query  478  SKIFDYQEFGYRRITVERP  496
            SKI+  + FG+ R+T+ERP
Sbjct  470  SKILKNESFGFTRVTIERP  488


 Score = 77.9 bits (276),  Expect = 2e-15, Method: Compositional matrix adjust.
 Identities = 37/115 (33%), Positives = 65/115 (57%), Gaps = 8/115 (6%)

Query  570  KLIVKHLSEHDDEAEVCKTKGKIEANPDLRDNENVPLTESVDDYFAREVLPHVPNAWIDT  629
            ++ + +   +++   V K +G    + +LRD E++PLTE +++YF RE+LP   +AW+D 
Sbjct  482  RVTIERPQRDENGDIVYKKNGSKSVDTNLRDTEDIPLTEDINEYFEREILPFNQDAWMDR  541

Query  630  KKTDEQDKEVGIVGYEIPFNRHFYEYVPPRSLTEIDADLDKVSSEIMQLLQEVHS  684
            KK          +GYEIPF R FY Y PP +   I   + ++   I++ +Q + +
Sbjct  542  KKDK--------IGYEIPFTRLFYKYTPPEPSEVISERIKQLEESIIKNFQALSG  588

90) Ksed_13670 in NC_013169


> NC_002953_R1|4|G3|49484939|YP_042160.1|Staphylococcus_aureus_subsp._aureus_MSSA476|-|4742..6529|-|SAS0027|type 
I restriction 
enzyme methylase
Length=595

 Score =  345 bits (1294),  Expect = 7e-96, Method: Compositional matrix adjust.
 Identities = 228/547 (42%), Positives = 370/547 (68%), Gaps = 21/547 (3%)

Query  1    MTESPSDDRKSTVTKPDPNFIWGIADMLRGPYRPKEYGTVILPFTVLARFESVLEPTKDA  60
            M+E   +++ S   + ++N+IW +AD+LRG Y+P EYG VILP TV+ R++  L  T+D 
Sbjct  1    MSEFKRHQQTSINVQKQANLIWNVADILRGLYKPHEYGKVILPMTVIKRLHDTLLKTRDK  60

Query  61   VLAASEKYESAPDLVRHEMLKRASGQEFYNISQFTLSTL-GDPANQAANLQNLIEGYNEE  119
            VL ++E+ +S  D++R+ +LK ASG  FYN S +T+ TL +DPAN  +N++  ++G++E+
Sbjct  61   VLKTAENTQSINDVMRERLLKNASGYSFYNTSLYTFETLLADPANIESNFRAYLNGFSEN  120

Query  120  VRQVFERFDMPKIIrdlddrdrlSAVVKEFAALDVH--PDRVSNAEMGDVFEELIRRFME  177
            ++++++ F     I  + D D L  V++EF   D    PD++++++MG VFEEL+R+F E
Sbjct  121  MQDILNNFKFDVEITTMADNDVLFYVIQEFNKADAYLGPDKMTSTDMGYVFEELVRKFSE  180

Query  178  ASKDVAGDYFTPREVVRLMVSLLFSPDTEDLSDPHLIRQVYDPTCGTGGMLSEAHEWMRE  237
            + ++ AG  FT+R+++ LM  LL+  D + L   H+++ VYD T GT+ MLS   E++++
Sbjct  181  SYNEEAGAHFTSRDIIYLMTDLLLIEDKDTLFKEHVFKTVYDQTMGTSQMLSAMTERIHD  240

Query  238  HNGHATLNLFGQEFNALSYAMAKADLIIKKQDAQNIFFGDTLLVDGHEGKTFSYCISNPP  297
             N+ A +  FGQE+N+ +YA++KAD +I+  D++N+ +G TL  D  EG TF YCISNPP
Sbjct  241  MNDTAEVATFGQELNPETYAISKADTMIRGGDPENMALGSTLTSDRFEGFTFDYCISNPP  300

Query  298  FGQDWKVQEKAVKAERERDGDEGRFAAGLPSVNDGAMLFLQHLVSKMRPAAQGGGRGAIV  357
            FG DWK ++KAVKAE+E  G+ GRF+ GLP V+DG +LF  + +SK++ +    GR AI+
Sbjct  301  FGVDWKKDQKAVKAEHEL-GELGRFGVGLPRVSDGQLLFQLNGISKLKET----GRMAII  355

Query  358  LNGSALFTGSAGQGPSEIRRHLLENDLVDAIIGLPTDLFYNTGIATYIWVLDNNKPQERR  417
             NGSALF+G++G G S IR+ ++END +++II LP DLFYNTGI+TYIW++ ++K+ ER+
Sbjct  356  HNGSALFSGNPGAGESLIRQYVIENDWLEGIIQLPNDLFYNTGISTYIWIITKDKSPERQ  415

Query  418  GKVQLIDGTAQWVKMRKSIGAKRRMLSEANITSIVDLYGEYED-----ADPEV-SKVFNT  471
            GKVQL+D++    K RK+IG KR  +SEA    IV+ YGE++D     +D  V SK+++ 
Sbjct  416  GKVQLVDASNMYEKRRKNIGEKRVDISEACREMIVQAYGEFNDKEYYLGDGTVESKILKN  475

Query  472  EDFGYRTITVEQPLRQ-----VYSVDEDR-IEAALNLTPIKKLDKETRHLLREALDSLDH  525
            E FG+  +T+E+P R+     VY  +  + +++ L  T    L  +  + +   + ++++
Sbjct  476  ESFGFTRVTIERPQRDENGDIVYKKNGSKSVDTNLRDTEDIPLTEDINEYFEREILPFNQ  535

Query  526  EQVWTER  532
            +  W +R
Sbjct  536  D-AWMDR  541


 Score = 84.4 bits (301),  Expect = 2e-17, Method: Compositional matrix adjust.
 Identities = 42/86 (49%), Positives = 58/86 (68%), Gaps = 0/86 (0%)

Query  563  AESSPQGEIVKGPKGRIEPDASLRDTENVPLTEDVDAYVEREVLPWAPEAWVDESKTKIG  622
            ++   +G+IV   +G    D++LRDTE++PLTED++ Y ERE+LP   +AW+D  K KIG
Sbjct  488  PQRDENGDIVYKKNGSKSVDTNLRDTEDIPLTEDINEYFEREILPFNQDAWMDRKKDKIG  547

Query  623  YEIPFTRAFYVYEPPRPLAEIDADVQ  648
            YEIPFTR FY Y PP P   I   ++
Sbjct  548  YEIPFTRLFYKYTPPEPSEVISERIK  573

91) hsdM1 in NC_021355


> NC_002953_R1|4|G3|49484939|YP_042160.1|Staphylococcus_aureus_subsp._aureus_MSSA476|-|4742..6529|-|SAS0027|type 
I restriction 
enzyme methylase
Length=595

 Score =  344 bits (1292),  Expect = 1e-95, Method: Compositional matrix adjust.
 Identities = 214/484 (45%), Positives = 345/484 (72%), Gaps = 18/484 (3%)

Query  5    QEKSSFIWNLADLLRGSYKRNEYQRVILPFTVLKRFDSVLEYSKKDVVDMYEKYKNITSN  64
            Q ++++IWN+AD+LRG YK +EY +VILP TV+KR++  L  ++  V+    K  + T +
Sbjct  15   QKQANLIWNVADILRGLYKPHEYGKVILPMTVIKRLHDTLLKTRDKVL----KTAENTQS  70

Query  65   IDPILKNVAVDEEDNKLGFYNFSIYNFDSLLKDPDNIEDNIIFYLDCFSDNVKDIFENFD  124
            I+ ++++  + +     +FYN S+Y F++LL DP NIE N+  YL+ FS+N++DI++NF 
Sbjct  71   INDVMRERLLKNASG-YSFYNTSLYTFETLLADPANIESNFRAYLNGFSENMQDILNNFK  129

Query  125  IKTEINNLSKANLLYLIVKKFSETNIDLSPKTVSNHEMGTIFEELIRKFSEQSNEEAGEH  184
            +  EI  ++  ++L+ +++ F+ ++  L+P  +++ +MG +FEEL+RKFSE  NEEAG H
Sbjct  130  FDVEITTMADNDVLFYVIQEFNKADAYLGPDKMTSTDMGYVFEELVRKFSESYNEEAGAH  189

Query  185  FTPRDVVKLMTELMFIEDDIN--EKESIKLIYDPACGTGGMLTSCKEFINNLNEDVDVVL  242
            FT+RD++ LMT+L++IED       + +K +YD + GT+ ML++  E I+++N+  +V  
Sbjct  190  FTSRDIIYLMTDLLLIEDKDTLFKEHVFKTVYDQTMGTSQMLSAMTERIHDMNDTAEVAT  249

Query  243  YGQEINPEIYAICKADMLMKGENANNIKGPSSTLSDDQLSSMKFDYMISNPPYGRNWELD  302
            +GQE+NPE YAI KAD +++G +++N+ + +STL+ D++ +  FDY ISNPP+G +W  D
Sbjct  250  FGQELNPETYAISKADTMIRGGDPENM-ALGSTLTSDRFEGFTFDYCISNPPFGVDWKKD  308

Query  303  EDVVKKESKCGFEGRFGAGIPRKSDGQLLFIEHMISKMKDNEKSRIAVITNSSPLFIGDA  362
            +  VK E   G  GRFG G+PR SDGQLLF  + ISK+K+   +R+A+I N+S+LF G++
Sbjct  309  QKAVKAEHELGELGRFGVGLPRVSDGQLLFQLNGISKLKET--GRMAIIHNGSALFSGNP  366

Query  363  GSGESEIRKWIIENDYLEAIIGLPNQLFFNTGIKTYIWILTNQKESKRKRKIQLIDATEE  422
            G+GES IR+ +IEND LE+II LPN+LF+NTGI TYIWI+T++K + R+ K+QL+DA++ 
Sbjct  367  GAGESLIRQYVIENDWLEGIIQLPNDLFYNTGISTYIWIITKDKSPERQGKVQLVDASNM  426

Query  423  YEPMKKNLGNKRHQISENNIHNILKYYKLYEEGD--------KVKILDNNDFGYTKVTIE  474
            YE  +KN+G+KR +ISE   + I++ Y  +++ +          KIL N+ FG+T+VTIE
Sbjct  427  YEKRRKNIGEKRVDISEACREMIVQAYGEFNDKEYYLGDGTVESKILKNESFGFTRVTIE  486

Query  475  RPKQ  478
            RP++
Sbjct  487  RPQR  490


 Score = 83.4 bits (297),  Expect = 4e-17, Method: Compositional matrix adjust.
 Identities = 45/104 (44%), Positives = 71/104 (69%), Gaps = 1/104 (0%)

Query  559  SFIKNVIEKLSEHDDTADYVIDKKGNKKADSNLRDYEKIPLKEDVDEYLKEEVFNYYPDA  618
            +F +  IE+ +++D+ +D V  K+G+K  D+NLRD E IPL ED++EY+  E++ +  DA
Sbjct  479  GFTRVTIER-PQRDENGDIVYKKNGSKSVDTNLRDTEDIPLTEDINEYFEREILPFNQDA  537

Query  619  WIDNKKNKIGYEINFTKYFYVYEKPRSLDEINKDIKDVTSEISR  662
            W+D KK+KIGYEI FT+ FY Y  P + + I+  IK++   I +
Sbjct  538  WMDRKKDKIGYEIPFTRLFYKYTPPEPSEVISERIKQLEESIIK  581

92) GYY_03180 in NC_015847


> NC_002953_R1|4|G3|49484939|YP_042160.1|Staphylococcus_aureus_subsp._aureus_MSSA476|-|4742..6529|-|SAS0027|type 
I restriction 
enzyme methylase
Length=595

 Score =  344 bits (1290),  Expect = 2e-95, Method: Compositional matrix adjust.
 Identities = 211/478 (45%), Positives = 336/478 (71%), Gaps = 13/478 (2%)

Query  5    QDKVGLIWDLADLLRGPYKRNEYQKVILPFTVLRRFDCVLKDTKPAVLQKYEQYCKVTGD  64
            Q +  LIW++AD+LRG YK +EY KVILP TV++R++  L  T+  VL+  E+   + + 
Sbjct  15   QKQANLIWNVADILRGLYKPHEYGKVILPMTVIKRLHDTLLKTRDKVLKTAENTQSINDV  74

Query  65   LDDAI-TPVSGYDFYNTSKYDFEELLKDPTHIKENLIHYVDSFSKNVREIFDYFAIKQQI  123
            + + +    SGY FYNTS Y FE LL DP++I  N+  Y+++FS N+++I++ F +  +I
Sbjct  75   MRERLLKNASGYSFYNTSLYTFETLLADPANIESNFRAYLNGFSENMQDILNNFKFDVEI  134

Query  124  ERLSKADllfkllkkfTESKVDLHPNVVSNQEMGYIFEELIRKFSEQSNEEAGDHFTPRE  183
              ++  D+LF +++ F  +   L P+ +++ +MGY+FEEL+RKFSE  NEEAG HFT+R+
Sbjct  135  TTMADNDVLFYVIQEFNKADAYLGPDKMTSTDMGYVFEELVRKFSESYNEEAGAHFTSRD  194

Query  184  VVELMTHLMFLPEDFDTDKKGIIRTVYDPACGTGGMLTGSKNYILELNPNIKVVLFGQEI  243
            ++ LMT+L+++ +     K  +++TVYD + GT+ ML++  + I ++N    V  FGQE+
Sbjct  195  IIYLMTDLLLIEDKDTLFKEHVFKTVYDQTMGTSQMLSAMTERIHDMNDTAEVATFGQEL  254

Query  244  QEEIYATCKADMLIKGEESDKIQGPLSTLSKDQFPFKKFDYCISNPPYGRKWELDQEAVL  303
            + E YA  KAD +I+G +++++    STL+ D+F    FDYCISNPP+G  W  DQ AV 
Sbjct  255  NPETYAISKADTMIRGGDPENMALG-STLTSDRFEGFTFDYCISNPPFGVDWKKDQKAVK  313

Query  304  EEAEKGYDGRFGAGTPRINDGQLLFLQHMVSKMHVDGQKSRIAVITNGSPLFTGDAGSGE  363
             E E G  GRFG G PR++DGQLLF  + +SK+    + +R+A+I NGS+LF+G++G+GE
Sbjct  314  AEHELGELGRFGVGLPRVSDGQLLFQLNGISKLK---ETGRMAIIHNGSALFSGNPGAGE  370

Query  364  SNIRKWLIENDYIEAIIALPNQLFYNTGINTYVWVMSNEKNPERKDKIQLIDGTSFFKKM  423
            S IR+ +IEND +E+II LPN+LFYNTGI+TY+W+++++K+PER++K+QL+D+++ + K 
Sbjct  371  SLIRQYVIENDWLEGIIQLPNDLFYNTGISTYIWIITKDKSPERQGKVQLVDASNMYEKR  430

Query  424  RKSLGNKRNELSKDHIENIVELYKNFKENEY--------SKIFESTEFGYTKVTVERP  473
            RK++G+KR ++S    E IV+ Y +F+++EY        SKI+ +  FG+T+VT+ERP
Sbjct  431  RKNIGEKRVDISEACREMIVQAYGEFNDKEYYLGDGTVESKILKNESFGFTRVTIERP  488


 Score = 84.9 bits (303),  Expect = 1e-17, Method: Compositional matrix adjust.
 Identities = 43/85 (51%), Positives = 65/85 (77%), Gaps = 2/85 (2%)

Query  556  AFVKSIMMALSEHDDTAEYVKDKKGVKA-DSNLRDNEKIPLNENIEEYFKREVLPYYNDA  614
            +F + + +  +++D+ ++ V  K+G K+ D+NLRD E IPL E+I+EYF RE+LP+ +DA
Sbjct  479  GFTR-VTIERPQRDENGDIVYKKNGSKSVDTNLRDTEDIPLTEDINEYFEREILPFNQDA  537

Query  615  WMDSKKDTVGYEINFTKYFYKYSAP  639
            WMD KKD +GYEI FT+ FYKY++P
Sbjct  538  WMDRKKDKIGYEIPFTRLFYKYTPP  562

93) Metev_0463 in NC_014253


> NC_002953_R1|4|G3|49484939|YP_042160.1|Staphylococcus_aureus_subsp._aureus_MSSA476|-|4742..6529|-|SAS0027|type 
I restriction 
enzyme methylase
Length=595

 Score =  343 bits (1288),  Expect = 2e-95, Method: Compositional matrix adjust.
 Identities = 215/486 (45%), Positives = 349/486 (72%), Gaps = 24/486 (4%)

Query  5    QEKANFIWSVADEVLRDDFKRGKYRDVILPFTVLRRVECVLEPTKDNVIQTYEN---VKD  61
            Q +AN+IW+VAD +LR+ +K   Y  VILP TV++R++  L  T+D+V++T EN   ++D
Sbjct  15   QKQANLIWNVAD-ILRGLYKPHEYGKVILPMTVIKRLHDTLLKTRDKVLKTAENTQSIND  73

Query  62   KVKDPHNALCHAAGHSFYNTSPYDLKKLLDDPSNIGQNFKSYINSFSENMRDIFDKFYLW  121
             +++    L +A+G SFYNTS Y +  LL DP+NI  NF++Y+N+FSENM+DI+++F + 
Sbjct  74   VMRER--LLKNASGYSFYNTSLYTFETLLADPANIESNFRAYLNGFSENMQDILNNFKFD  131

Query  122  NYIDQLIEDNLLYMLLEKFSNVD--LHPDSVSNHEMGYIFEELIRRFNEDVNENPGEHFT  179
              I  + ++++L+ +++ F++ D  L PD +++ +MGY+FEEL+R+F+E  NE++G HFT
Sbjct  132  VEITTMADNDVLFYVIQEFNKADAYLGPDKMTSTDMGYVFEELVRKFSESYNEEAGAHFT  191

Query  180  PREVIRLMVNLIFYQDEAKLGHNTPIRTIYDPACGTGGMLTIANDHILKEINSNADIWLF  239
            +R++I LM +L++ +D   L  +  ++T+YD + GT+ ML+   ++I  ++N  A++  F
Sbjct  192  SRDIIYLMTDLLLIEDKDTLFKEHVFKTVYDQTMGTSQMLSAMTERI-HDMNDTAEVATF  250

Query  240  GQEVNPETFAIAKSDMMLKGNDRDAENIKMGSVFSNDGHPNETFNYMLSNPPFGKDWKKE  299
            GQE+NPET+AI+K+D M++G D  +EN+ +GS +++D     TF+Y +SNPPFG DWKK+
Sbjct  251  GQELNPETYAISKADTMIRGGD--PENMALGSTLTSDRFEGFTFDYCISNPPFGVDWKKD  308

Query  300  QNFI-LEEAKSASSRFTAGLPRKDDGQLLFLQHMISKMKRPEDGGSRIAVVTNGSPLFTG  358
            Q+ +  E+  +  +RF  GLPR  DGQLLF  + ISK+K      +R+A++ NGS+LF+G
Sbjct  309  QKAVKAEHELGELGRFGVGLPRVSDGQLLFQLNGISKLK----ETGRMAIIHNGSALFSG  364

Query  359  DAGSGESEIRRWIIENDWLEAIVALPEQLFYNTGINTYVWIVTNRKEDHRKGKIQLVDAR  418
            ++G+GES IR+ +IENDWLE+I+ LP++LFYNTGI+TY+WI+T+ K  +R+GK+QLVDA 
Sbjct  365  NPGAGESLIRQYVIENDWLEGIIQLPNDLFYNTGISTYIWIITKDKSPERQGKVQLVDAS  424

Query  419  ECYQKMRKSLGEKRHEISSEQIDTITNLHNNFNEGQY--------SQIFDNHEFGYRKIT  470
            + Y+K RK++GEKR +IS    + I +   +FN+ +Y        S+I+ N+ FG+ ++T
Sbjct  425  NMYEKRRKNIGEKRVDISEACREMIVQAYGEFNDKEYYLGDGTVESKILKNESFGFTRVT  484

Query  471  IEQPLR  476
            IE+P R
Sbjct  485  IERPQR  490


 Score = 65.2 bits (228),  Expect = 1e-11, Method: Compositional matrix adjust.
 Identities = 39/89 (44%), Positives = 53/89 (60%), Gaps = 8/89 (8%)

Query  571  SERDETADICVDSKKRWEPDSQLRDYENVPLDEDIYDYFEREVKPHVPEAWIDESKTDQY  630
            ++RDE +DI    +     D++LRD E++PL EDI +YFERE+ P   +AW+D  K    
Sbjct  488  PQRDENGDIVYKKNGSKSVDTNLRDTEDIPLTEDINEYFEREILPFNQDAWMDRKK----  543

Query  631  DNDVGKVGYIINFNRYFYEYEPPRPLEEI  659
                +K+GY I F R FY Y PP P E I
Sbjct  544  ----DKIGYEIPFTRLFYKYTPPEPSEVI  568

94) Ksed_22800 in NC_013169


> NC_002953_R1|4|G3|49484939|YP_042160.1|Staphylococcus_aureus_subsp._aureus_MSSA476|-|4742..6529|-|SAS0027|type 
I restriction 
enzyme methylase
Length=595

 Score =  343 bits (1286),  Expect = 3e-95, Method: Compositional matrix adjust.
 Identities = 212/481 (45%), Positives = 326/481 (68%), Gaps = 13/481 (2%)

Query  7    EDKVAFVWRIADRLRGTFKQHEYGSVMLPLLVLRRMDAALADTKAEVVAQAKGWDTIGPG  66
            + +  ++W +AD LRG +K HEYG V+LP+ V++R++ +L  T+  V+  A   ++I   
Sbjct  15   QKQANLIWNVADILRGLYKPHEYGKVILPMTVIKRLHDTLLKTRDKVLKTAENTQSINDV  74

Query  67   -QDKLLKRTSRRPFYNTSPLTFAGLLNDADNLRENLAKYIRHLSPEAARVIEAYDFDPKI  125
             +++LLK +S  +FYNTS  TF  LL D+ N+  N+  Y+  +S +   +++ + FD  I
Sbjct  75   MRERLLKNASGYSFYNTSLYTFETLLADPANIESNFRAYLNGFSENMQDILNNFKFDVEI  134

Query  126  ERMDRDDILYGVIADFADLD--LRTSVVSNEAMGYIFEELLRKFSEMSNETAGEHYTPRE  183
              M  +D+L+ VI +F   D  L    +++  MGY+FEEL+RKFSE  NE AG H+T+R+
Sbjct  135  TTMADNDVLFYVIQEFNKADAYLGPDKMTSTDMGYVFEELVRKFSESYNEEAGAHFTSRD  194

Query  184  VISLMVQLLLTGKTHTELMENPRPVRTVYDPAAGTGGMLVGALDGVQGLNGNATVTVSGQ  243
            +I LM +LLL    +T + E+    +TVYD + GT+ ML +  + ++++N+ A V+  GQ
Sbjct  195  IIYLMTDLLLIEDKDTLFKEHV--FKTVYDQTMGTSQMLSAMTERIHDMNDTAEVATFGQ  252

Query  244  ELNDETWAIAQSDLMMLGIGPERMARGNSLTQDAFPTEQFDFMLANPPYGVDWKKYAGPI  303
            ELN ET AI+++D M+ G +PE MA G++LT D F    FD+ ++NPP+GVDWKK   ++
Sbjct  253  ELNPETYAISKADTMIRGGDPENMALGSTLTSDRFEGFTFDYCISNPPFGVDWKKDQKAV  312

Query  304  KDEAENLGFSGRFGAGTPRVSDGSFLFLQHMISKMKPGGSRIGIVLSGSPLFSGQAGSGE  363
            K E E LG  GRFG G PRVSDG +LF  + ISK+K  G R++I+ +GS+LFSG++G+GE
Sbjct  313  KAEHE-LGELGRFGVGLPRVSDGQLLFQLNGISKLKETG-RMAIIHNGSALFSGNPGAGE  370

Query  364  SEIRGWILENDWLEGIVALPDQMFYNTGISTYVWILTNDKDGASRGKVRLIDAREMGTKM  423
            S IR  ++ENDWLEGI+ LP+++FYNTGISTY+WI+T+DK    +GKV+L+DA +M  K 
Sbjct  371  SLIRQYVIENDWLEGIIQLPNDLFYNTGISTYIWIITKDKSPERQGKVQLVDASNMYEKR  430

Query  424  RKSLGDKRKELKPEAIRE-ITNLYGGALDE--FADDPRV--RVMNRNDFGYQRITVERPM  478
            RK++G+KR ++ +EA RE I + YG   D   + +D  V  ++++ + FG+ R+T+ERP 
Sbjct  431  RKNIGEKRVDI-SEACREMIVQAYGEFNDKEYYLGDGTVESKILKNESFGFTRVTIERPQ  489

Query  479  R  479
            R
Sbjct  490  R  490


 Score = 70.8 bits (249),  Expect = 3e-13, Method: Compositional matrix adjust.
 Identities = 45/113 (40%), Positives = 65/113 (58%), Gaps = 17/113 (15%)

Query  532  DEEAPVILKK-GEPAPDPDLRDAENIPLPDGWMDLPENRRFSTLDEAAEKHLHTEIHPYV  590
            DE++ ++ KK G  + D +LRD+E+IPL                 E  +  ++ EI P+ 
Sbjct  491  DENGDIVYKKNGSKSVDTNLRDTEDIPLT----------------EDINEYFEREILPFN  534

Query  591  PDAWLDYSKTKVGYEIPFTRQFYVYEPPRPVDEIAAEIKELEEQIQGWMKGLG  643
             DAW+D  K K+GYEIPFTR FY Y PP P + I+  IK+LEE I    ++L+
Sbjct  535  QDAWMDRKKDKIGYEIPFTRLFYKYTPPEPSEVISERIKQLEESIIKNFQALS  587

95) B932_2648 in NC_019396


> NC_002953_R1|4|G3|49484939|YP_042160.1|Staphylococcus_aureus_subsp._aureus_MSSA476|-|4742..6529|-|SAS0027|type 
I restriction 
enzyme methylase
Length=595

 Score =  343 bits (1287),  Expect = 3e-95, Method: Compositional matrix adjust.
 Identities = 214/489 (44%), Positives = 336/489 (69%), Gaps = 16/489 (3%)

Query  5    EIRNLSGFAWSVAEILRGDFKQSEYGKVILPFVVLRRLDCILETSKAQVLDAAKALPDGV  64
            ++++ + + W+VA+ILRG +K  EYGKVILP  V++RL+  L  ++ +VL +A    +++
Sbjct  13   NVQKQANLIWNVADILRGLYKPHEYGKVILPMTVIKRLHDTLLKTRDKVLKTAEN-TQSI  71

Query  65   DEATRDMILFGAVGGNVKVYNLSRFTFATLKGQDPGQLHQNLVDYITNFSSNVRDIFLDK  124
            ++  R+ +L    ++    YN S +TF TL + DP++++ N+  Y+  FS N++DI L++
Sbjct  72   NDVMRERLL--KNASGYSFYNTSLYTFETLLA-DPANIESNFRAYLNGFSENMQDI-LNN  127

Query  125  FLFTDQIKRLKDGGILWNVFQRMTEID--LHPNRVTNIEMGYLFEELIRRFSEISNETAG  182
            F F  +I  + D ++L  V+Q     D  L P+++T+ +MGY+FEEL+R+FSE  NE AG
Sbjct  128  FKFDVEITTMADNDVLFYVIQEFNKADAYLGPDKMTSTDMGYVFEELVRKFSESYNEEAG  187

Query  183  EHFTPREVIRLIVDLLIANDDTKLTKRGIIRQVYDPACGTGGMLALTEEALQDFNPSIRV  242
             HFT+R++I L+ DLL+ +D   L K  +++ VYD + GT+ ML+   E ++D N +  V
Sbjct  188  AHFTSRDIIYLMTDLLLIEDKDTLFKEHVFKTVYDQTMGTSQMLSAMTERIHDMNDTAEV  247

Query  243  ELFGQEINAESFGICKSDMLVTGHDPEQIAFGNTLTQDAHKDKRFHYMLSNPPYGVDWKK  302
              FGQE+N+E+++I K+D ++ G DPE++A+G+TLT D   +  F+Y +SNPP+GVDWKK
Sbjct  248  ATFGQELNPETYAISKADTMIRGGDPENMALGSTLTSDRFEGFTFDYCISNPPFGVDWKK  307

Query  303  YQDPIKEEADTLGFSGRFGAGTPRISDGQLLFLQHMISKMRDDEDGSRIGIVMNGSPLFT  362
             Q ++K E + LG  GRFG G PR+SDGQLLF  + ISK++   + +R++I+ NGS+LF+
Sbjct  308  DQKAVKAEHE-LGELGRFGVGLPRVSDGQLLFQLNGISKLK---ETGRMAIIHNGSALFS  363

Query  363  GGAGSGESEIRRWMFENDWVEAIVALPTDLFYNTGIQTYIWLLTNRKPANRQGKVQLIDA  422
            G +G+GES IR+ ++ENDW+E+I+ LP DLFYNTGI TYIW++T+ K+++RQGKVQL+DA
Sbjct  364  GNPGAGESLIRQYVIENDWLEGIIQLPNDLFYNTGISTYIWIITKDKSPERQGKVQLVDA  423

Query  423  SGERFWKSMRKSLGSKRREIPEEARADIVRIYEGFLNGGN--GEGDV-AKIFDVDDFGYR  479
            S        RK++G KR +I+E  R  IV+ Y  F +     G+G V +KI+  + FG+ 
Sbjct  424  SN--MYEKRRKNIGEKRVDISEACREMIVQAYGEFNDKEYYLGDGTVESKILKNESFGFT  481

Query  480  EIRIERPLR  488
             + IERP R
Sbjct  482  RVTIERPQR  490


 Score = 73.9 bits (261),  Expect = 3e-14, Method: Compositional matrix adjust.
 Identities = 44/109 (41%), Positives = 67/109 (62%), Gaps = 8/109 (7%)

Query  564  SERDEEADICTDKDGNPEPNTDLRDYEFVPLKEDWREYVAREVTPFAPDTWVDESYRDAR  623
            ++RDE++DI   K+G+   +T+LRD E +PL ED  EY  RE+ PF  D+W+        
Sbjct  488  PQRDENGDIVYKKNGSKSVDTNLRDTEDIPLTEDINEYFEREILPFNQDAWM--------  539

Query  624  DHEIGRIGYEINFNRYFYRYAPPRPLEKIDVELKALETEIAELLREIAA  672
            D+  ++IGYEI F R FY+Y+PP P E I   +K LE  I   ++ +++
Sbjct  540  DRKKDKIGYEIPFTRLFYKYTPPEPSEVISERIKQLEESIIKNFQALSG  588

96) CLOAM0217 in NC_020449


> NC_002953_R1|4|G3|49484939|YP_042160.1|Staphylococcus_aureus_subsp._aureus_MSSA476|-|4742..6529|-|SAS0027|type 
I restriction 
enzyme methylase
Length=595

 Score =  340 bits (1277),  Expect = 2e-94, Method: Compositional matrix adjust.
 Identities = 212/491 (44%), Positives = 334/491 (69%), Gaps = 21/491 (4%)

Query  9    ASFIWSICNLLRGPYKRNEYRKVILPFTVLKRFDCILAPTKDNVLAELPHLYGKSDNIIS  68
            A++IW++ ++LRG YK +EY KVILP TV+KR++  L  T+D+VL    +     ++++ 
Sbjct  18   ANLIWNVADILRGLYKPHEYGKVILPMTVIKRLHDTLLKTRDKVLKTAENT-QSINDVMR  76

Query  69   ESLIR-ITGVPFYNKSRLDMKKLLDDTENIAINLQSYINDFSPNVQKIIEYFAFSEQIAR  127
            E L++  +G +FYN S      LL D  NI  N+++Y+N+FS N+Q I++ F F  +I+ 
Sbjct  77   ERLLKNASGYSFYNTSLYTFETLLADPANIESNFRAYLNGFSENMQDILNNFKFDVEITT  136

Query  128  LQDANLLYLVLQRFVTDELDLSPQAVDNIQMGLVFEELIRIGAEQSNEEAGEHFTPREVI  187
            + D ++L+ V+Q F   +  L+P+ + + +MG VFEEL+R  +E  NEEAG HFT+R++I
Sbjct  137  MADNDVLFYVIQEFNKADAYLGPDKMTSTDMGYVFEELVRKFSESYNEEAGAHFTSRDII  196

Query  188  KLMVNLLLSPEAD-LAKSHVVKTIFDPACGTGGMLTAAETYIKELNRDAKPHLYGQDWNK  246
             LM +LLL  + D L K HV KT++D + GT+ ML+A    I ++N  A    +GQ+ N 
Sbjct  197  YLMTDLLLIEDKDTLFKEHVFKTVYDQTMGTSQMLSAMTERIHDMNDTAEVATFGQELNP  256

Query  247  ESYAVCCSDMLIK-GEVAKIHYGCSFEQDGFSTDKFDYMLANPPFGVEWKKQQKTITDEH  305
            E+YA+  +D +I+ G+  ++  G ++  D F    FDY ++NPPFGV+WKK+QK++  EH
Sbjct  257  ETYAISKADTMIRGGDPENMALGSTLTSDRFEGFTFDYCISNPPFGVDWKKDQKAVKAEH  316

Query  306  EKLGYNGRFGAGLPRINDGSLLFLQHMISKMRSVEEGGSRIGIVFNGSPLFTGDAGSGES  365
            E LG  GRFG GLPR++DG LLF  + ISK++      +R++I+ NGS+LF+G++G+GES
Sbjct  317  E-LGELGRFGVGLPRVSDGQLLFQLNGISKLKET----GRMAIIHNGSALFSGNPGAGES  371

Query  366  NIRKWIIENDWLEAIIAMPDQLFYNTGISTYIWIITNKKEAHRKGKIQLIDARQFYNKMR  425
             IR+ +IENDWLE+II +P++LFYNTGISTYIWIIT+ K ++R+GK+QL+DA + Y+K R
Sbjct  372  LIRQYVIENDWLEGIIQLPNDLFYNTGISTYIWIITKDKSPERQGKVQLVDASNMYEKRR  431

Query  426  KSLGNKRNIIGDGEDNRFDHISLITRIHSDFIDNQELEFTCNGTTKTAIVSKIFDNKDFG  485
            K++G+KR  I+++         +I +  ++F D++   +  +GT    + SKI+ N  FG
Sbjct  432  KNIGEKRVDISEA------CREMIVQAYGEFNDKE--YYLGDGT----VESKILKNESFG  479

Query  486  YQKITVERPLR  496
            + ++T+ERP R
Sbjct  480  FTRVTIERPQR  490


 Score = 85.2 bits (304),  Expect = 1e-17, Method: Compositional matrix adjust.
 Identities = 48/92 (53%), Positives = 61/92 (67%), Gaps = 0/92 (0%)

Query  590  SERDETADICRDSKGMPEADTELRDTENVPLKEDIDTYFKREVLPHVPDAWIDYSKTKIG  649
            ++RDE +DI    +G    DT+LRDTE++PL EDI+ YF RE+LP   DAW+D  K KIG
Sbjct  488  PQRDENGDIVYKKNGSKSVDTNLRDTEDIPLTEDINEYFEREILPFNQDAWMDRKKDKIG  547

Query  650  YEIPFNRHFYVYQPPRGLEVIEAELFNIEKEI  681
            YEIPF R FY Y PP   EVI   + ++E  I
Sbjct  548  YEIPFTRLFYKYTPPEPSEVISERIKQLEESI  579

97) PST_0252 in NC_009434


> NC_002953_R1|4|G3|49484939|YP_042160.1|Staphylococcus_aureus_subsp._aureus_MSSA476|-|4742..6529|-|SAS0027|type 
I restriction 
enzyme methylase
Length=595

 Score =  339 bits (1271),  Expect = 4e-94, Method: Compositional matrix adjust.
 Identities = 209/484 (44%), Positives = 331/484 (69%), Gaps = 18/484 (3%)

Query  1    MNQQTLAPFIWNIADLLLGAFKPSEYGRIILPFTVLRRLECVLEPTRDKV-RSQFESMKA  59
            +N Q  A +IWN+AD+L G +KP EYG++ILP TV++RL+  L  TRDKV ++  ++   
Sbjct  12   INVQKQANLIWNVADILRGLYKPHEYGKVILPMTVIKRLHDTLLKTRDKVLKTAENTQSI  71

Query  60   SGVDMDLILPTTAGATFYNVSQFSLGSV--GSTSTRANLEDYIAKFSANARQVFEHFAFD  117
            ++V  + +L  ++G +FYN S +++ ++  ++++  +N+  Y+  FS N ++++++F FD
Sbjct  72   NDVMRERLLKNASGYSFYNTSLYTFETLLADPANIESNFRAYLNGFSENMQDILNNFKFD  131

Query  118  TWLAKLENRNLLYLVTQKFAAVD--LHPDKISNHEMGLVFEHLIRKFAESSNDDAGQYFT  175
              ++ + + ++L+ V Q F   D  L PDK+++ +MG VFE+L+RKF+ES N++AG  FT
Sbjct  132  VEITTMADNDVLFYVIQEFNKADAYLGPDKMTSTDMGYVFEELVRKFSESYNEEAGAHFT  191

Query  176  PRDVVRLATTLVFAPDHQALNGEGVVRTVYDCAAGTGGFLSSAIEQVYEWNPNARLVPYA  235
            +RD++ L T L++  D ++L  E V +TVYD + GT+  LS+  E++ + N  A +  ++
Sbjct  192  SRDIIYLMTDLLLIEDKDTLFKEHVFKTVYDQTMGTSQMLSAMTERIHDMNDTAEVATFG  251

Query  236  QELNPETYAISVADKLIQGYDTRNIKLGNTLSDDHLPHEQFDYCLANPPFGVKWENVQKQ  295
            QELNPETYAIS AD +I+G D  N+ LG+TL+ D++    FDYC++NPPFGV W + QK 
Sbjct  252  QELNPETYAISKADTMIRGGDPENMALGSTLTSDRFEGFTFDYCISNPPFGVDWKKDQKA  311

Query  296  VQAEHSQQGFAGRFGAGLPRVGDGSLLFLMHLLSKRKPVELGGSRIGIVLSGSPLFNGGA  355
            V+AEH    + GRFG GLPRV+DG LLF ++ +SK K      +R++I+ +GS+LF+G +
Sbjct  312  VKAEHELGEL-GRFGVGLPRVSDGQLLFQLNGISKLK----ETGRMAIIHNGSALFSGNP  366

Query  356  GSGESEIRRWILENDWLEAIIALPTDLFYNTGIGTYIWVLSNHKDALRKGKVQLIDASAM  415
            G+GES IR+ ++ENDWLE+II LP DLFYNTGI+TYIW+++++K + R+GKVQL+DAS M
Sbjct  367  GAGESLIRQYVIENDWLEGIIQLPNDLFYNTGISTYIWIITKDKSPERQGKVQLVDASNM  426

Query  416  HAPMRKSLGSKRKYLSDEQIAEIAKLHEAFEE--------GPNSKIFATTDFGYRRITVE  467
                RK++G KR  +S+     I +    F++          +SKI+    FG+ R+T+E
Sbjct  427  YEKRRKNIGEKRVDISEACREMIVQAYGEFNDKEYYLGDGTVESKILKNESFGFTRVTIE  486

Query  468  RPLR  471
            RP R
Sbjct  487  RPQR  490


 Score = 75.0 bits (265),  Expect = 1e-14, Method: Compositional matrix adjust.
 Identities = 39/99 (40%), Positives = 59/99 (60%), Gaps = 8/99 (8%)

Query  532  ERDANAQPVLDDKGNQQADSDLREFENVPLNQNIDDYFAREVLPHVPDAWIDTGKTDAKD  591
            +RD N++ V   +G++  D++LR+ E++PL ++I++YF RE+LP   DAW+D  K     
Sbjct  489  QRDENGDIVYKKNGSKSVDTNLRDTEDIPLTEDINEYFEREILPFNQDAWMDRKKDK---  545

Query  592  GQVGIVGYEINFNRYFYVYQPPRPLAEIDADLKAVEAEI  630
                 +GYEI F R FY Y PP P   I   +K +E  I
Sbjct  546  -----IGYEIPFTRLFYKYTPPEPSEVISERIKQLEESI  579

98) SACE_0871 in NC_009142


> NC_002953_R1|4|G3|49484939|YP_042160.1|Staphylococcus_aureus_subsp._aureus_MSSA476|-|4742..6529|-|SAS0027|type 
I restriction 
enzyme methylase
Length=595

 Score =  339 bits (1273),  Expect = 4e-94, Method: Compositional matrix adjust.
 Identities = 211/481 (44%), Positives = 333/481 (70%), Gaps = 13/481 (2%)

Query  2    ANHAWSVADLLRGDYKQSDYGKVILPFTVLRRLECVLKPTRGKVLETVEKYRN-RDLDPD  60
            AN  W+VAD+LRG YK  +YGKVILP TV++RL+  L  TR+KVL T E+ ++  D+  +
Sbjct  18   ANLIWNVADILRGLYKPHEYGKVILPMTVIKRLHDTLLKTRDKVLKTAENTQSINDVMRE  77

Query  61   TFLRKASGHRFYNTTPLTLKSIVADSSHVARNLTQYIGGFSPNAYEVLERYDFAQQIKKL  120
             +L++ASG  FYNT+  T+ +++AD++++  N+  Y+ GFS N  ++L+ + F  +I  +
Sbjct  78   RLLKNASGYSFYNTSLYTFETLLADPANIESNFRAYLNGFSENMQDILNNFKFDVEITTM  137

Query  121  DGANLLYKVTSTFADLD--LRPEVVDNHQMGYIFEELIRRFAEQSNETAGEHFTPREVIE  178
             + ++L+ V   F   D  L P+ + + +MGY+FEEL+R+F+E  NE AG HFT+R++I 
Sbjct  138  ADNDVLFYVIQEFNKADAYLGPDKMTSTDMGYVFEELVRKFSESYNEEAGAHFTSRDIIY  197

Query  179  LMVNLLIAPDDEALSKPGVIRRVLDPACGTGGMLSAAYEHITTMNADATVEVYGQELNPE  238
            LM +LL+  D ++L K  V++ V D + GT+ MLSA  E+I  MN  A V  +GQELNPE
Sbjct  198  LMTDLLLIEDKDTLFKEHVFKTVYDQTMGTSQMLSAMTERIHDMNDTAEVATFGQELNPE  257

Query  239  SWAICRSDLMIKDQDPDNIKFGNSFSDDGHYRRTFHYLLANPPFGVEWKKVKEDVEGDLE  298
            + AI ++D MI++ DP+N+ +G++++ D     TF+Y ++NPPFGV+WKK +  V ++ +
Sbjct  258  TYAISKADTMIRGGDPENMALGSTLTSDRFEGFTFDYCISNPPFGVDWKKDQKAVKAE-H  316

Query  299  QLGENSRFWPALPRINDGSLLFLQHMLSKMNSVEDGGGRVAIVFNGSPLFTGAAGSGESQ  358
            +LGE +RF  +LPR++DG LLF  + +SK++      GR+AI+ NGS+LF+G +G+GES 
Sbjct  317  ELGELGRFGVGLPRVSDGQLLFQLNGISKLKET----GRMAIIHNGSALFSGNPGAGESL  372

Query  359  IRQHILENDWLEAVVALPDQLFYNTGISTYFWILTNRKSPDYKGKVVLLDAREYWQKMRK  418
            IRQ ++ENDWLE+++ LP++LFYNTGISTY+WI+T+ KSP+ +GKV L+DA +  +K RK
Sbjct  373  IRQYVIENDWLEGIIQLPNDLFYNTGISTYIWIITKDKSPERQGKVQLVDASNMYEKRRK  432

Query  419  SLGDKRKYVASDQIAEITRLYAEALQVAKDENHPLHGKV--KVFENDDFGYRRITVERPL  476
            ++G+KR  ++      I + Y+E       E    +G V  K++ N+ FG+ R+T+ERP 
Sbjct  433  NIGEKRVDISEACREMIVQAYGE---FNDKEYYLGDGTVESKILKNESFGFTRVTIERPQ  489

Query  477  K  477
            +
Sbjct  490  R  490


 Score = 84.9 bits (303),  Expect = 2e-17, Method: Compositional matrix adjust.
 Identities = 45/90 (50%), Positives = 60/90 (67%), Gaps = 1/90 (1%)

Query  555  RDPEGEVQIAK-GETEPDPELRDYENVPLDQDVEDYLEREVLPHVPDAWIDHTKTKIGYE  613
            RD +G++   K G    D +LRD E++PL +D+++Y+ERE+LP   DAW+D+ K KIGYE
Sbjct  490  RDENGDIVYKKNGSKSVDTNLRDTEDIPLTEDINEYFEREILPFNQDAWMDRKKDKIGYE  549

Query  614  IPFTRHFYVYEPPRPLAEIDAELKALEAEI  643
            IPFTR FY Y PP P   I   +K LE  I
Sbjct  550  IPFTRLFYKYTPPEPSEVISERIKQLEESI  579

99) Sfri_2608 in NC_008345


> NC_002953_R1|4|G3|49484939|YP_042160.1|Staphylococcus_aureus_subsp._aureus_MSSA476|-|4742..6529|-|SAS0027|type 
I restriction 
enzyme methylase
Length=595

 Score =  338 bits (1267),  Expect = 1e-93, Method: Compositional matrix adjust.
 Identities = 215/503 (43%), Positives = 344/503 (69%), Gaps = 44/503 (8%)

Query  9    AALLWSVADILRGDFKQSQYGRIILPFTLLRRLECVLEATKPDVLAKYEAVKAMPLEAQD  68
            A L+W+VADILRG +K  +YG++ILP T+++RL+  L  T+  VL   E  +++    ++
Sbjct  18   ANLIWNVADILRGLYKPHEYGKVILPMTVIKRLHDTLLKTRDKVLKTAENTQSINDVMRE  77

Query  69   KLLTHTAQLSFYNTSKMDLHRL--GEMGIASNLESYIQSFSPNAREIFEHFDFFNTIDKL  126
            +LL +++  SFYNTS   ++ L  +   I SN+ +Y+++FS N ++I+++F F   I  +
Sbjct  78   RLLKNASGYSFYNTSLYTFETLLADPANIESNFRAYLNGFSENMQDILNNFKFDVEITTM  137

Query  127  AEADLLYKVAKQFANAP--LSPENISNYGMGLVFEELIRRFAESSNETAGEHFTPRDIVR  184
            A+ D+L+ V ++F +A   L+P+++++ +MG VFEEL+R+F+ES NE AG HFT+RDI+ 
Sbjct  138  ADNDVLFYVIQEFNKADAYLGPDKMTSTDMGYVFEELVRKFSESYNEEAGAHFTSRDIIY  197

Query  185  LTTSLVFSNDDDVLTQAGLVRSIYDPTAGTGGFLSSGMEYLHELNEKASLSAFGQELNPE  244
            L T L++ +D D L +  + +++YD T GT+  LS+  E +H++N+ A +++FGQELNPE
Sbjct  198  LMTDLLLIEDKDTLFKEHVFKTVYDQTMGTSQMLSAMTERIHDMNDTAEVATFGQELNPE  257

Query  245  SYAICKADMLIKGQKVDNIKLGNTLSNDLLRNDKFDYMLSNPPFGVDWKKIQKFINTEYT  304
            +YAI KAD +I+G   +N+ LG+TL++D +    FDY +SNPPFGVDWKK QK +++E  
Sbjct  258  TYAISKADTMIRGGDPENMALGSTLTSDRFEGFTFDYCISNPPFGVDWKKDQKAVKAE-H  316

Query  305  DKGFEGRFGAGLPRVSDGSLLFLMHLVSKMRPKHEGGSRIGIILNGSPLFTGGAGSGESE  364
            + G  GRFG GLPRVSDG LLF ++ +SK++      +R++II NGS+LF+G +G+GES 
Sbjct  317  ELGELGRFGVGLPRVSDGQLLFQLNGISKLK----ETGRMAIIHNGSALFSGNPGAGESL  372

Query  365  IRRYILENDLLEAIVALPSDMFYNTGISTYVWILSSNKGASHNGARKGKVQLINASKERA  424
            IR+Y++END LE+I+ LP+D+FYNTGISTY+WI++ +K++     R+GKVQL++AS+   
Sbjct  373  IRQYVIENDWLEGIIQLPNDLFYNTGISTYIWIITKDKSP----ERQGKVQLVDASN---  425

Query  425  KTggrgrsgggESDEVVENIFYAPMRKSLGSKRKELTEDGIETIVKTYGQFIENDF----  480
                                 Y   RK++G KR +++E   E IV++YG+F ++++    
Sbjct  426  --------------------MYEKRRKNIGEKRVDISEACREMIVQAYGEFNDKEYYLGD  465

Query  481  ----SKIFDYHVFGYRRITVERP  499
                SKI+  + FG+ R+T+ERP
Sbjct  466  GTVESKILKNESFGFTRVTIERP  488


 Score = 67.3 bits (236),  Expect = 3e-12, Method: Compositional matrix adjust.
 Identities = 34/108 (32%), Positives = 61/108 (57%), Gaps = 8/108 (7%)

Query  569  KLIVKHLGEHDDDAQLCKAKGRVEANPDLRDFENVPLTESIYKYFDREVIPHVPNAWIDK  628
            ++ + +   ++++  + K +G    + +LRD E++PLTE I  YF+RE++P   +AW+D+
Sbjct  482  RVTIERPQRDENGDIVYKKNGSKSVDTNLRDTEDIPLTEDINEYFEREILPFNQDAWMDR  541

Query  629  TKTDPKDHEVGIVGYEIPFNRHFYEYASPRELEDIDADLDIVSTEIMQ  676
             K          +GYEIPF R FY Y++P   E I   +  +   I++
Sbjct  542  KKDK--------IGYEIPFTRLFYKYTPPEPSEVISERIKQLEESIIK  581

100) LPC_2790 in NC_009494


> NC_002953_R1|4|G3|49484939|YP_042160.1|Staphylococcus_aureus_subsp._aureus_MSSA476|-|4742..6529|-|SAS0027|type 
I restriction 
enzyme methylase
Length=595

 Score =  334 bits (1254),  Expect = 1e-92, Method: Compositional matrix adjust.
 Identities = 210/498 (43%), Positives = 342/498 (69%), Gaps = 24/498 (4%)

Query  3    NENNKKIQNLSTFSWSIAEILRGDFKQSEYGKVILPFVVLRRLDCILEPSKDAVISAYEN  62
            ++ + ++Q+ + + W++A+ILRG +K  EYGKVILP  V++RL+  L  ++D V+ + EN
Sbjct  8    QQTSINVQKQANLIWNVADILRGLYKPHEYGKVILPMTVIKRLHDTLLKTRDKVLKTAEN  67

Query  63   LPEGIDDHTKDMMLFSAVGGGLKVYNYNTLTFSKIRNQDPGDVHKNLLDYITSFNSSVRD  122
              ++I+D  ++ +L    ++G   YN +  TF  +   DP++++ N+  Y+ +F+ +++D
Sbjct  68   -TQSINDVMRERLL--KNASGYSFYNTSLYTFETLLA-DPANIESNFRAYLNGFSENMQD  123

Query  123  IFLEKFLFTDQLKRLKDGGILWQVFDRFCQID--LHPDNVSNMEMGYLFEDLIRRFSEIS  180
            I L++F F  ++  + D ++L  V++ F + D  L PD++++ +MGY+FE+L+R+FSE  
Sbjct  124  I-LNNFKFDVEITTMADNDVLFYVIQEFNKADAYLGPDKMTSTDMGYVFEELVRKFSESY  182

Query  181  NETAGEHFTPREVIRLIVDLLLINDAEALAGSGIIRTVYDPACGTGGMLALMEEAMKEYN  240
            NE AG HFT+R++I L+ DLLLI+D ++L    +++TVYD + GT+ ML+ M E + + N
Sbjct  183  NEEAGAHFTSRDIIYLMTDLLLIEDKDTLFKEHVFKTVYDQTMGTSQMLSAMTERIHDMN  242

Query  241  SKIRVELYGQELNPESFGICTSDMLVTGHNPEQIAFGNTLTEDAHKDKKFHYMLSNPPYG  300
                V  +GQELNPE+++I  +D ++ G +PE++A+G+TLT D   +  F+Y +SNPP+G
Sbjct  243  DTAEVATFGQELNPETYAISKADTMIRGGDPENMALGSTLTSDRFEGFTFDYCISNPPFG  302

Query  301  VDWKKYQDPIKQEAQEKGMDGRFGAGLPRISDGQLLFLQHMISKMRDDEVGSRIGIVMNG  360
            VDWKK Q ++K E +E G  GRFG GLPR+SDGQLLF  + ISK+++    +R++I+ NG
Sbjct  303  VDWKKDQKAVKAE-HELGELGRFGVGLPRVSDGQLLFQLNGISKLKE---TGRMAIIHNG  358

Query  361  SPLFTGGAGSGESEIRRWMFENDWVEAIIALPTDLFYNTGIQTYVWMLTNKKDKNRRGKV  420
            S+LF+G +G+GES IR+ ++ENDW+E+II LP DLFYNTGI TY+W++T+ K  +R+GKV
Sbjct  359  SALFSGNPGAGESLIRQYVIENDWLEGIIQLPNDLFYNTGISTYIWIITKDKSPERQGKV  418

Query  421  QLIDASSERFWQSMRKSLGSKRREISDHARSEIVKIY-------YEMLNGGGDWSEFSKI  473
            QL+DAS+    +  RK++G KR +IS+  R  IV+ Y       Y + +G  +    SKI
Sbjct  419  QLVDASN--MYEKRRKNIGEKRVDISEACREMIVQAYGEFNDKEYYLGDGTVE----SKI  472

Query  474  FDRQEFGYREIRIERPLR  491
            +  + FG+  + IERP R
Sbjct  473  LKNESFGFTRVTIERPQR  490


 Score = 78.9 bits (280),  Expect = 1e-15, Method: Compositional matrix adjust.
 Identities = 47/102 (47%), Positives = 63/102 (62%), Gaps = 8/102 (7%)

Query  568  SEKDETADICCDAKGNPEPDTDLRDHELVPLKEDWREYVEREVKPFVADAWVDENHKDAT  627
            +++DE +DI    +G+   DT+LRD E +PL ED  EY ERE+ PF  DAW+D       
Sbjct  488  PQRDENGDIVYKKNGSKSVDTNLRDTEDIPLTEDINEYFEREILPFNQDAWMDR------  541

Query  628  DGKVGRVGYEINFNRYFYKYVPPRPVAEINEELKQLEAEIAN  669
              K +++GYEI F R FYKY PP P   I+E +KQLE  I +
Sbjct  542  --KKDKIGYEIPFTRLFYKYTPPEPSEVISERIKQLEESIIK  581

101) Dd1591_4253 in NC_012912


> NC_002953_R1|4|G3|49484939|YP_042160.1|Staphylococcus_aureus_subsp._aureus_MSSA476|-|4742..6529|-|SAS0027|type 
I restriction 
enzyme methylase
Length=595

 Score =  334 bits (1252),  Expect = 2e-92, Method: Compositional matrix adjust.
 Identities = 216/506 (43%), Positives = 343/506 (68%), Gaps = 37/506 (7%)

Query  10   ANFIWSICNLLRGPYKRNEYRKVILPLTVLRRFECLLEPTRQDALAEFQWLKTKPERVQQ  69
            AN+IW++ ++LRG YK +EY KVILP+TV++R++  L  TR+  L   +  ++  + +++
Sbjct  18   ANLIWNVADILRGLYKPHEYGKVILPMTVIKRLHDTLLKTRDKVLKTAENTQSINDVMRE  77

Query  70   ARLQQITGYRFYNLSRMQL-TLSGENIHSllddpnnlapnlnSYINGFSANVRAIMERFK  128
              L++ +GY FYN S   + TL ++  +        + +N+ +Y+NGFS N++ I++ FK
Sbjct  78   RLLKNASGYSFYNTSLYTFETLLADPAN--------IESNFRAYLNGFSENMQDILNNFK  129

Query  129  FSEQITHMAEKNILFEVVKAFAKID--LSPQRVDQMQMGYVFEELIRIGAEQSNEEAGEH  186
            F  +IT MA++++LF V++ F K D  L+P+++   +MGYVFEEL+R  +E  NEEAG H
Sbjct  130  FDVEITTMADNDVLFYVIQEFNKADAYLGPDKMTSTDMGYVFEELVRKFSESYNEEAGAH  189

Query  187  FTPREVIKLMVNLLLAPEED-LAKSDVVKTIYDPACGTGGMLSVAEEYIRHLNSDARPHL  245
            FT+R++I LM +LLL  + D L K +V KT+YD + GT+ MLS   E I+++N  A    
Sbjct  190  FTSRDIIYLMTDLLLIEDKDTLFKEHVFKTVYDQTMGTSQMLSAMTERIHDMNDTAEVAT  249

Query  246  YGQDWNDEAWAVCKSDMLIKGEDADNIILGDTFTRDGFDRDSDGNKWIFDYMLANPPFGV  305
            +GQ+ N E+ A+ K+D +I+G D++N+ LG T+T D F+         FDY ++NPPFGV
Sbjct  250  FGQELNPETYAISKADTMIRGGDPENMALGSTLTSDRFE------GFTFDYCISNPPFGV  303

Query  306  EWKQQQKYIQKEADELGYAGRFGAGTPRINDGALLFLQHMISKMRPVNKDGSRIGIVFNG  365
            +WK++QK + K  +ELG  GRFG G PR++DG LLF  + ISK+    K+ +R++I+ NG
Sbjct  304  DWKKDQKAV-KAEHELGELGRFGVGLPRVSDGQLLFQLNGISKL----KETGRMAIIHNG  358

Query  366  SPLFTGDAGSGESEIRRWIIENDWLEAIVALPEQLFYNTGIATYIWVITNRKAKERKGKV  425
            S+LF+G++G+GES IR+ +IENDWLE+I+ LP++LFYNTGI+TYIW+IT+ K+ ER+GKV
Sbjct  359  SALFSGNPGAGESLIRQYVIENDWLEGIIQLPNDLFYNTGISTYIWIITKDKSPERQGKV  418

Query  426  QLIDARNFWVPMEKSLGNKRRRIGDPQDRPKDPNHIAEITRIYENFQDGETRTFFLDGKE  485
            QL+DA N      K++G+KR  I+++            I + Y +F+D   + ++L++  
Sbjct  419  QLVDASNMYEKRRKNIGEKRVDISEA--------CREMIVQAYGEFND---KEYYLGD--  465

Query  486  KELVVSKLFDNDDFGYHKITVERPLR  511
               V SK++ N+ FG+ ++T+ERP R
Sbjct  466  -GTVESKILKNESFGFTRVTIERPQR  490


 Score = 82.8 bits (295),  Expect = 7e-17, Method: Compositional matrix adjust.
 Identities = 46/100 (46%), Positives = 64/100 (64%), Gaps = 0/100 (0%)

Query  609  ERDETAEICKDKKGEPEADTDLRDTETVPLKESIEEYFQREVLLHVPDAWIDYAKTKIGY  668
            +RDE ++I   K+G    DT+LRDTE +PL E I+EYF+RE+L    DAW+D  K KIGY
Sbjct  489  QRDENGDIVYKKNGSKSVDTNLRDTEDIPLTEDINEYFEREILPFNQDAWMDRKKDKIGY  548

Query  669  EIPLNRHFYRYEEPRELTEIEAEIKGLESEILELLKEVTA  708
            EIP+ R FY+Y  P     I   IK LE  I+  ++ +++
Sbjct  549  EIPFTRLFYKYTPPEPSEVISERIKQLEESIIKNFQALSG  588

102) Tbd_2680 in NC_007404


> NC_002953_R1|4|G3|49484939|YP_042160.1|Staphylococcus_aureus_subsp._aureus_MSSA476|-|4742..6529|-|SAS0027|type 
I restriction 
enzyme methylase
Length=595

 Score =  331 bits (1243),  Expect = 8e-92, Method: Compositional matrix adjust.
 Identities = 199/487 (41%), Positives = 329/487 (68%), Gaps = 24/487 (4%)

Query  22   SNFIWSIADLLRGPYRPPQYERVMLPLVVLRRFDCVLESTKDAVLAKYAQYQGKLEGDAL  81
            +N+IW++AD+LRG Y+P +Y +V+LP+ V++R++  L  T+D VL K A+    +++   
Sbjct  18   ANLIWNVADILRGLYKPHEYGKVILPMTVIKRLHDTLLKTRDKVL-KTAENTQSINDVMR  76

Query  82   DGVLNKISGQRFHNHSPLSFEKLKGDPDNAHLHLVSYINGFSENVRKIFERFEFGNEIER  141
            + +L++ SG  F N S  +FE L +DP N + ++ +Y+NGFSEN++ I++ F F+ EI  
Sbjct  77   ERLLKNASGYSFYNTSLYTFETLLADPANIESNFRAYLNGFSENMQDILNNFKFDVEITT  136

Query  142  MREHNILFLVIKKFCEVD--LHPGAVDNIEMGLLFEDLIRRFNEQANETAGDHFTPREVI  199
            M ++++LF VI+ F   D  L P+ + + +MG +FE+L+R+F+E  NE AG HFT+R++I
Sbjct  137  MADNDVLFYVIQEFNKADAYLGPDKMTSTDMGYVFEELVRKFSESYNEEAGAHFTSRDII  196

Query  200  RLMVSLLFMHDDDLLSKPGTVRKMLDPTCGTGGMLSETRKYLREHQSGARLFVYGQDFNP  259
             LM  LL+++D D L K    + + D T GT+ MLS     +++ +  A +  +GQ++NP
Sbjct  197  YLMTDLLLIEDKDTLFKEHVFKTVYDQTMGTSQMLSAMTERIHDMNDTAEVATFGQELNP  256

Query  260  RSYAVAASDLLLRTNLADAETSTIKFGDTLIDDQFPGERFDYFLANPPFGVDWKRQQKDV  319
             +YA++ +D ++R    +++   + +G TL  D+F G  FDY ++NPPFGVDWK++QK V
Sbjct  257  ETYAISKADTMIR----GGDPENMALGSTLTSDRFEGFTFDYCISNPPFGVDWKKDQKAV  312

Query  320  VREHEKQGFAGRFGAGTPRVNDGALLFLQHMVSKFEPVDPANNLDGSRLAIVFNGSPLFT  379
              EHE   + GRFG G PRV+DG LLF  + +SK+         + +R+AI+ NGS+LF+
Sbjct  313  KAEHELGEL-GRFGVGLPRVSDGQLLFQLNGISKLK--------ETGRMAIIHNGSALFS  363

Query  380  GGAGSGESEIRKWIIENDWLEAIVAMPEQMFYNTGIGTYVWVVTNRKEARRRGRIQLIDG  439
            G +G+GES IR+ +IENDWLE+I+ +P+++FYNTGI+TY+W++T+ K + R+G++QL+D+
Sbjct  364  GNPGAGESLIRQYVIENDWLEGIIQLPNDLFYNTGISTYIWIITKDKSPERQGKVQLVDA  423

Query  440  RDRWQSLRRSLGDKRREFSDAHITDIVREYGDMRDN--------ATSKVFDNADFGYNRL  491
             +  +  R+++G+KR ++S+A    IV+ YG+  D+          SK++ N  FG+ R+
Sbjct  424  SNMYEKRRKNIGEKRVDISEACREMIVQAYGEFNDKEYYLGDGTVESKILKNESFGFTRV  483

Query  492  TIERPLR  498
            TIERP R
Sbjct  484  TIERPQR  490


 Score = 77.1 bits (273),  Expect = 4e-15, Method: Compositional matrix adjust.
 Identities = 40/96 (42%), Positives = 64/96 (67%), Gaps = 3/96 (3%)

Query  577  VIAKKAGGKVEYEPDPKLRDFENVPLTEDVEAYFEHGVRPHVADAWIDHAKTKVGYEINF  636
            ++ KK G+K     D +LRD E++PLTED++ YFE+ + P   DAW+D+ K K+GYEI F
Sbjct  496  IVYKKNGSK---SVDTNLRDTEDIPLTEDINEYFEREILPFNQDAWMDRKKDKIGYEIPF  552

Query  637  NRHFYRFTLPRPLAEIDADLKRAEEEIVRLLREVTA  672
             R FY++T P P   I   +K+ EE I++ ++ +++
Sbjct  553  TRLFYKYTPPEPSEVISERIKQLEESIIKNFQALSG  588

103) Halru_2807 in NC_019964


> NC_002953_R1|4|G3|49484939|YP_042160.1|Staphylococcus_aureus_subsp._aureus_MSSA476|-|4742..6529|-|SAS0027|type 
I restriction 
enzyme methylase
Length=595

 Score =  330 bits (1240),  Expect = 1e-91, Method: Compositional matrix adjust.
 Identities = 202/483 (42%), Positives = 336/483 (70%), Gaps = 19/483 (3%)

Query  6    NEKADFIWSIADLLRGDYRQSEYQKVILPLTVLRRLDCVTERHQEEVRERYEQLQEQGIE  65
            + +A++IW++AD+LRG Y+  EY KVILP+TV++RL+    + ++ V    E+   Q+I+
Sbjct  15   QKQANLIWNVADILRGLYKPHEYGKVILPMTVIKRLHDTLLKTRDKVLKTAEN--TQSIN  72

Query  66   NVAPA--LKQAANAEVYNTSEYTFKSLCNDPDDIAENLQYYINQYDEETKEIFEKFDFDH  123
            +V     LK+A+    YNTS YTF +L  DP +I  N++ Y+N + E+ ++I+++F FD 
Sbjct  73   DVMRERLLKNASGYSFYNTSLYTFETLLADPANIESNFRAYLNGFSENMQDILNNFKFDV  132

Query  124  QIQRLEEANLLYKVVRQF--AELPLHPDEVPNEEMGYIYEELIRKFNELSNETAGEHFTP  181
            +I  + + ++L+ V+++F  A+  L PD + + +MGY++EEL+RKF+E  NE AG HFT+
Sbjct  133  EITTMADNDVLFYVIQEFNKADAYLGPDKMTSTDMGYVFEELVRKFSESYNEEAGAHFTS  192

Query  182  REVIELMVNLVFQEDDEALTEQDAIRTVYDPACGTGGMLSVAEEYVRELNTDANLHVFGQ  241
            R++I LM +L++ ED ++L  ++ ++TVYD + GT+ MLS   E ++++N  A++  FGQ
Sbjct  193  RDIIYLMTDLLLIEDKDTLFKEHVFKTVYDQTMGTSQMLSAMTERIHDMNDTAEVATFGQ  252

Query  242  ELNPESYAVCNSDMLIKGQEPENIIYGNSFTEDGFPSRTFEYMLSNPPFGVSWKKVKDEI  301
            ELNPE+YA+ ++D +I+G +PEN+  G+++T D F + TF+Y +SNPPFGV WKK  +  
Sbjct  253  ELNPETYAISKADTMIRGGDPENMALGSTLTSDRFEGFTFDYCISNPPFGVDWKK-DQKA  311

Query  302  VreheeegfagrfgagTPRTNDGAFLFLQHMISKMKRPAEGGSRIAIVFNGSPLFNGGPN  361
            V+ ++E G  GRFG G PR +DG +LF  + ISK+K      +R+AI+ NGS+LF+G P 
Sbjct  312  VKAEHELGELGRFGVGLPRVSDGQLLFQLNGISKLK----ETGRMAIIHNGSALFSGNPG  367

Query  362  SGESAIRRWILENDWLEAIVGLPENLFYNTGIRTYIWVLSNNKPKKREDVVQLIDAQDLY  421
            +GES IR+ ++ENDWLE+I+ LP++LFYNTGI TYIW+++++K+  R++ VQL+DA ++Y
Sbjct  368  AGESLIRQYVIENDWLEGIIQLPNDLFYNTGISTYIWIITKDKSPERQGKVQLVDASNMY  427

Query  422  AEMDESLGEKRHELTQEHINEISRIFGDL--------EANGRSKVVPTEEFGYRRIVIDR  473
                 ++GEKR ++++   + I + +G++        ++   SK++  E FG+ R+ I+R
Sbjct  428  EKRRKNIGEKRVDISEACREMIVQAYGEFNDKEYYLGDGTVESKILKNESFGFTRVTIER  487

Query  474  PLR  476
            P R
Sbjct  488  PQR  490


 Score = 64.5 bits (225),  Expect = 2e-11, Method: Compositional matrix adjust.
 Identities = 38/110 (35%), Positives = 65/110 (60%), Gaps = 12/110 (10%)

Query  547  AIERALGEQNDDAEICRDGNGNPEHDGDLRERERVPLGTDLQEYFEEEVAPYLENAWINE  606
            +IER+  +++++++I    NG+   D +LR+ E +PL  D++EYFE E+ P+ ++AW++ 
Sbjct  484  TIERP--QRDENGDIVYKKNGSKSVDTNLRDTEDIPLTEDINEYFEREILPFNQDAWMDR  541

Query  607  SSKYHDDQDEELGVVGYEINFDRYFYEYEEPRALEDINEEIAQVESEIVS  656
                        + +GYEI F R FY Y  P + E I+E I Q+E  I+ 
Sbjct  542  KK----------DKIGYEIPFTRLFYKYTPPEPSEVISERIKQLEESIIK  581

104) Teth514_1222 in NC_010320


> NC_002953_R1|4|G3|49484939|YP_042160.1|Staphylococcus_aureus_subsp._aureus_MSSA476|-|4742..6529|-|SAS0027|type 
I restriction 
enzyme methylase
Length=595

 Score =  330 bits (1240),  Expect = 1e-91, Method: Compositional matrix adjust.
 Identities = 214/534 (41%), Positives = 352/534 (66%), Gaps = 48/534 (8%)

Query  17   LCNAAGQSFCNSSPFCLRDLTSRAKKQTLKADFIAYLDGFSPNVQEILDKFKFRNQIDTM  76
            L NA+G SF N+S + +  L + +    + ++F AYL+GFS N+Q+IL++FKF  +I TM
Sbjct  80   LKNASGYSFYNTSLYTFETLLADP--ANIESNFRAYLNGFSENMQDILNNFKFDVEITTM  137

Query  77   IDADILGAVIEKFVSPTINLSPNPVYKDDEKKEIRLPGLDNHTMGVIFEELIRRFNEENN  136
             D D+L  VI+ F  +   L+P+               + +  MG +FEEL+R+F+E  N
Sbjct  138  ADNDVLFYVIQEFNKADAYLGPDK--------------MTSTDMGYVFEELVRKFSESYN  183

Query  137  EEAGEHFTPRDVVELMADLIFVPVADKI-KDATY-SCYDGACGTGGMLTVAQDRLIELAE  194
            EEAG HFT+RD++ LM+DL+++   D + K+  + + YD + GT+ ML+   +R+ ++ +
Sbjct  184  EEAGAHFTSRDIIYLMTDLLLIEDKDTLFKEHVFKTVYDQTMGTSQMLSAMTERIHDMND  243

Query  195  KAGRKVSIHLFGQEINPETYAIAKSDLLLQGQGDQADHIGFGSTLSNDQFPTYQFDFMLS  254
             A     +  FGQE+NPETYAI+K+D +++G  ++++++++GSTL++D+F  + FD+ +S
Sbjct  244  TAE----VATFGQELNPETYAISKADTMIRG--GDPENMALGSTLTSDRFEGFTFDYCIS  297

Query  255  NPPYGKSWKVDADKLGGKKDIMD-SRFVTNFADDPNFSMIPRTSDGQLLFLLNNVAKMKK  313
            NPP+G  WK D   + +  ++ + +RF            +PR SDGQLLF LN ++K+K 
Sbjct  298  NPPFGVDWKKDQKAVKAEHELGELGRFGVG---------LPRVSDGQLLFQLNGISKLKE  348

Query  314  TTELGSRIVEVHNGSSLFTGDAGSGESNARRYLIENDLVEAIIALPENMFYNTGIGTYIW  373
            T    +R+  +HNGS+LF+G++G+GES  R+Y+IEND +E+II LP+++FYNTGI+TYIW
Sbjct  349  T----GRMAIIHNGSALFSGNPGAGESLIRQYVIENDWLEGIIQLPNDLFYNTGISTYIW  404

Query  374  VLSNNKAEHRKSKIQLIDATLLKSPLRKNLGKKNCEFTSEIRRQILDLYMAFEENEY---  430
            +++++K+ +R++K+QL+DA+ +    RKN+G K  +++   R  I++ Y  F+++EY   
Sbjct  405  IITKDKSPERQGKVQLVDASNMYEKRRKNIGEKRVDISEACREMIVQAYGEFNDKEYYLG  464

Query  431  -----SKIFDNNEFGYWKVTVLRPAYNEDGTIQKDKKGKPVVNKELTDTEQIPFTYEGGI  485
                 SKI+ N+ FG+ +VT+ RP  +E+G I   K+G   V+ +L DTE+IP+T   +I
Sbjct  465  DGTVESKILKNESFGFTRVTIERPQRDENGDIVYKKNGSKSVDTNLRDTEDIPLT--EDI  522

Query  486  EAFFEKEVKPFAPDAWIDEKQTKIGYEISFTKYFYKPIQLRTLEEITADIRALE  539
            + +FE+E+ PF  DAW+D K+ KIGYEI+FT+ FYK       E I+  I+ LE
Sbjct  523  NEYFEREILPFNQDAWMDRKKDKIGYEIPFTRLFYKYTPPEPSEVISERIKQLE  576

105) PCC8801_3935 in NC_011726


> NC_002953_R1|4|G3|49484939|YP_042160.1|Staphylococcus_aureus_subsp._aureus_MSSA476|-|4742..6529|-|SAS0027|type 
I restriction 
enzyme methylase
Length=595

 Score =  326 bits (1222),  Expect = 4e-90, Method: Compositional matrix adjust.
 Identities = 205/481 (43%), Positives = 342/481 (72%), Gaps = 19/481 (3%)

Query  7    KVSFIWSVADLIRDSFKRGKYQDVILPFTVLRRLDCVLEPTKEQVLEAYHKYHGKLENL-  65
            + ++IW+VAD++R+ +K   Y  VILP TV++RL+  L  T+++VL + ++ ++  + + 
Sbjct  17   QANLIWNVADILRGLYKPHEYGKVILPMTVIKRLHDTLLKTRDKVLKTAENTQSINDVMR  76

Query  66   DPILCKQSGFAFYNASNYDFGKLIDDPKDLGANLKKYINSFSSNMREVLEKFDFPNTIDK  125
            + +L + SG++FYN+S Y F  L+ DP ++ +N++ Y+N+FS NM+++L++F F   I  
Sbjct  77   ERLLKNASGYSFYNTSLYTFETLLADPANIESNFRAYLNGFSENMQDILNNFKFDVEITT  136

Query  126  LEEADLLFQVMEKFKTID--LHPDKVSNLEMGYIFEELIRKFNEALDENPGEHFTPREVI  183
            + + D+LF V++ F+  D  L PDK+++ +MGY+FEEL+RKF+E+ +E++G HFT+R++I
Sbjct  137  MADNDVLFYVIQEFNKADAYLGPDKMTSTDMGYVFEELVRKFSESYNEEAGAHFTSRDII  196

Query  184  RLMVslllsqdkdslkqAHITRTIYDPCCGSGGMLTIAKERILELNPNATVFLFGQEVNP  243
             LM  LLL +DKD+L + H+ +T+YD   G++ ML+   ERI ++N  A V  FGQE+NP
Sbjct  197  YLMTDLLLIEDKDTLFKEHVFKTVYDQTMGTSQMLSAMTERIHDMNDTAEVATFGQELNP  256

Query  244  ETFAICKSDLYMKSEDGKDADNIKFGSTLSNDQHSDKSFDYLLANPPYGKDWKRDKDAVE  303
            ET+AI K+D  ++   G D++N+ +GSTL++D+  + +FDY ++NPP+G DWK+D+ AV 
Sbjct  257  ETYAISKADTMIR---GGDPENMALGSTLTSDRFEGFTFDYCISNPPFGVDWKKDQKAVK  313

Query  304  TEAQKTG-SRFSAGTPRISDGQLLFLQQMLARMKSPENGGSRVAIVMNGSPLFTGDAGSG  362
            +E +    +RF+ G PR+SDGQLLF  + ++++K      +R+AI+ NGS+LF+G++G+G
Sbjct  314  AEHELGELGRFGVGLPRVSDGQLLFQLNGISKLKET----GRMAIIHNGSALFSGNPGAG  369

Query  363  ESEIRRWILENDWLEAIIALPEQLFYNTGISTYIWILSNkkllqkkekvqlINGSDFWVA  422
            ES IR+ ++ENDWLE+II LP++LFYNTGISTYIWI+++ K  +++ KVQL+++S+    
Sbjct  370  ESLIRQYVIENDWLEGIIQLPNDLFYNTGISTYIWIITKDKSPERQGKVQLVDASNMYEK  429

Query  423  MRKSLGDKRREISTEHIEKITAIFQDFEVSE--------VSKTFNSTDFGYRKITIERPL  474
             RK++G+KR +IS    E I   + +F+  E         SK +++  FG+ ++TIERP 
Sbjct  430  RRKNIGEKRVDISEACREMIVQAYGEFNDKEYYLGDGTVESKILKNESFGFTRVTIERPQ  489

Query  475  R  475
            R
Sbjct  490  R  490


 Score = 74.4 bits (263),  Expect = 2e-14, Method: Compositional matrix adjust.
 Identities = 45/115 (40%), Positives = 68/115 (60%), Gaps = 8/115 (6%)

Query  560  FKAILTGLSEKDETAEICRDKDGNPEPDTELRDTENVPLDEDIYDYFEREVKPHVSDAWI  619
            F  +    +++DE ++I   K+G+   DT+LRDTE++PL EDI +YFERE+ P   DAW+
Sbjct  480  FTRVTIERPQRDENGDIVYKKNGSKSVDTNLRDTEDIPLTEDINEYFEREILPFNQDAWM  539

Query  620  NETVRDSKDSGVGKVGYEINFNRYFYQYQPPRELSEIEKDIQQVEGEILAMLKEM  674
                    D   +K+GYEI F R FY+Y PP     I   I+Q+E  I+  ++ +
Sbjct  540  --------DRKKDKIGYEIPFTRLFYKYTPPEPSEVISERIKQLEESIIKNFQAL  586

106) Cyan8802_3984 in NC_013161


> NC_002953_R1|4|G3|49484939|YP_042160.1|Staphylococcus_aureus_subsp._aureus_MSSA476|-|4742..6529|-|SAS0027|type 
I restriction 
enzyme methylase
Length=595

 Score =  326 bits (1222),  Expect = 4e-90, Method: Compositional matrix adjust.
 Identities = 205/481 (43%), Positives = 342/481 (72%), Gaps = 19/481 (3%)

Query  7    KVSFIWSVADLIRDSFKRGKYQDVILPFTVLRRLDCVLEPTKEQVLEAYHKYHGKLENL-  65
            + ++IW+VAD++R+ +K   Y  VILP TV++RL+  L  T+++VL + ++ ++  + + 
Sbjct  17   QANLIWNVADILRGLYKPHEYGKVILPMTVIKRLHDTLLKTRDKVLKTAENTQSINDVMR  76

Query  66   DPILCKQSGFAFYNASNYDFGKLIDDPKDLGANLKKYINSFSSNMREVLEKFDFPNTIDK  125
            + +L + SG++FYN+S Y F  L+ DP ++ +N++ Y+N+FS NM+++L++F F   I  
Sbjct  77   ERLLKNASGYSFYNTSLYTFETLLADPANIESNFRAYLNGFSENMQDILNNFKFDVEITT  136

Query  126  LEEADLLFQVMEKFKTID--LHPDKVSNLEMGYIFEELIRKFNEALDENPGEHFTPREVI  183
            + + D+LF V++ F+  D  L PDK+++ +MGY+FEEL+RKF+E+ +E++G HFT+R++I
Sbjct  137  MADNDVLFYVIQEFNKADAYLGPDKMTSTDMGYVFEELVRKFSESYNEEAGAHFTSRDII  196

Query  184  RLMVslllsqdkdslkqAHITRTIYDPCCGSGGMLTIAKERILELNPNATVFLFGQEVNP  243
             LM  LLL +DKD+L + H+ +T+YD   G++ ML+   ERI ++N  A V  FGQE+NP
Sbjct  197  YLMTDLLLIEDKDTLFKEHVFKTVYDQTMGTSQMLSAMTERIHDMNDTAEVATFGQELNP  256

Query  244  ETFAICKSDLYMKSEDGKDADNIKFGSTLSNDQHSDKSFDYLLANPPYGKDWKRDKDAVE  303
            ET+AI K+D  ++   G D++N+ +GSTL++D+  + +FDY ++NPP+G DWK+D+ AV 
Sbjct  257  ETYAISKADTMIR---GGDPENMALGSTLTSDRFEGFTFDYCISNPPFGVDWKKDQKAVK  313

Query  304  TEAQKTG-SRFSAGTPRISDGQLLFLQQMLARMKSPENGGSRVAIVMNGSPLFTGDAGSG  362
            +E +    +RF+ G PR+SDGQLLF  + ++++K      +R+AI+ NGS+LF+G++G+G
Sbjct  314  AEHELGELGRFGVGLPRVSDGQLLFQLNGISKLKET----GRMAIIHNGSALFSGNPGAG  369

Query  363  ESEIRRWILENDWLEAIIALPEQLFYNTGISTYIWILSNkkllqkkekvqlINGSDFWVA  422
            ES IR+ ++ENDWLE+II LP++LFYNTGISTYIWI+++ K  +++ KVQL+++S+    
Sbjct  370  ESLIRQYVIENDWLEGIIQLPNDLFYNTGISTYIWIITKDKSPERQGKVQLVDASNMYEK  429

Query  423  MRKSLGDKRREISTEHIEKITAIFQDFEVSE--------VSKTFNSTDFGYRKITIERPL  474
             RK++G+KR +IS    E I   + +F+  E         SK +++  FG+ ++TIERP 
Sbjct  430  RRKNIGEKRVDISEACREMIVQAYGEFNDKEYYLGDGTVESKILKNESFGFTRVTIERPQ  489

Query  475  R  475
            R
Sbjct  490  R  490


 Score = 75.0 bits (265),  Expect = 2e-14, Method: Compositional matrix adjust.
 Identities = 45/115 (40%), Positives = 69/115 (60%), Gaps = 8/115 (6%)

Query  560  FKAILTGLSEKDETAEICRDKDGNPEPDTELRDTENVPLDEDIYDYFEREVKPHVSDAWI  619
            F  +    +++DE ++I   K+G+   DT+LRDTE++PL EDI +YFERE+ P   DAW+
Sbjct  480  FTRVTIERPQRDENGDIVYKKNGSKSVDTNLRDTEDIPLTEDINEYFEREILPFNQDAWM  539

Query  620  NETVRDSKDSGVGKVGYEINFNRYFYQYQPPRELSEIEKDIQQVEGAILAMLKEM  674
                    D   +K+GYEI F R FY+Y PP     I   I+Q+E +I+  ++ +
Sbjct  540  --------DRKKDKIGYEIPFTRLFYKYTPPEPSEVISERIKQLEESIIKNFQAL  586

107) Tery_4473 in NC_008312


> NC_002953_R1|4|G3|49484939|YP_042160.1|Staphylococcus_aureus_subsp._aureus_MSSA476|-|4742..6529|-|SAS0027|type 
I restriction 
enzyme methylase
Length=595

 Score =  325 bits (1218),  Expect = 7e-90, Method: Compositional matrix adjust.
 Identities = 213/504 (43%), Positives = 332/504 (66%), Gaps = 43/504 (8%)

Query  10   VSFIWGIADDVLRDIYVRGKYRDVILPMTVIRRLDCLLEPTKAAVLKENNFYENM-EISD  68
             ++IW +AD +LR++Y    Y  VILPMTVI+RL+  L  T+  VLK  +  +++ ++  
Sbjct  18   ANLIWNVAD-ILRGLYKPHEYGKVILPMTVIKRLHDTLLKTRDKVLKTAENTQSINDVMR  76

Query  69   KSGLTEFTKYPFYNTSGFTLKKLLDEPRSIKENLIDYLNGFSDNVQEIINKFKFRNQLET  128
               L + + Y+FYNTS +T+  LL +P +I  N+  YLNGFS+N+Q+I+N+FKF  ++ T
Sbjct  77   ERLLKNASGYSFYNTSLYTFETLLADPANIESNFRAYLNGFSENMQDILNNFKFDVEITT  136

Query  129  LVEHKRLYALIQKFTDSDINLSPEPRKDKKGKVIQPGLSNLGMGYVFEELIRKFNEENNE  188
            + ++  L+ +IQ F  +D  L+P+             +++ +MGYVFEEL+RKF+E  NE
Sbjct  137  MADNDVLFYVIQEFNKADAYLGPDK------------MTSTDMGYVFEELVRKFSESYNE  184

Query  189  EAGEHFTPRDIIKLMVNLIFMPVKDQI-KNTTY-LVYDCACGSGGMLTEAENFLLELATG  246
            EAG HFT+RDII LM +L+++  KD + K+  +  VYD + G++ ML+     + E   +
Sbjct  185  EAGAHFTSRDIIYLMTDLLLIEDKDTLFKEHVFKTVYDQTMGTSQMLSA----MTERIHD  240

Query  247  MGKKVVIHLFGQEVNPETYAICQADMLIKVKETDNIKYASTLASDGFPDFTFDFMLANPP  306
            M     +  FGQE+NPETYAI +AD +I+  + +N+  +STL+SD F +FTFD+ ++NPP
Sbjct  241  MNDTAEVATFGQELNPETYAISKADTMIRGGDPENMALGSTLTSDRFEGFTFDYCISNPP  300

Query  307  YGKSWKVDQDKILVGRKKEVKD-NRFLVKHQGEELQLIPRSSDGQLLFLVNKLSKMKDST  365
            +G  WK DQ  +   +  E+ +  RF V         +PR SDGQLLF +N +SK+K++ 
Sbjct  301  FGVDWKKDQKAVKAEH--ELGELGRFGVG--------LPRVSDGQLLFQLNGISKLKET-  349

Query  366  KLGSRIAIVHNGSALFTGDAGSGESNIRRWIIENDWLECIVGLPLNMFYNTGIATYIWII  425
               +R+AI+HNGSALF+G++G+GES IR+ +IENDWLE I+ LP ++FYNTGI+TYIWII
Sbjct  350  ---GRMAIIHNGSALFSGNPGAGESLIRQYVIENDWLEGIIQLPNDLFYNTGISTYIWII  406

Query  426  SNKKSVERRGKVQLIDGREWYGKLRKSLGSKSCELRGEDIDRITEEFLDFSESD------  479
            ++ KS ER+GKVQL+D+ + Y K RK++G K  ++     + I + + +F++ +      
Sbjct  407  TKDKSPERQGKVQLVDASNMYEKRRKNIGEKRVDISEACREMIVQAYGEFNDKEYYLGDG  466

Query  480  --NSRIFDNEDFGFHKIVVERPLR  501
              +S+I+ NE FGF ++ +ERP R
Sbjct  467  TVESKILKNESFGFTRVTIERPQR  490


 Score = 70.0 bits (246),  Expect = 5e-13, Method: Compositional matrix adjust.
 Identities = 39/76 (52%), Positives = 55/76 (73%), Gaps = 4/76 (5%)

Query  572  TEKDERGEAVILKQTKKGVVYQADAELRDTENVPLKENIQEYFEREVLPHVSDAWIDFDK  631
             ++DE G+ V  K+  K+V    D++LRDTE++PL E+I+EYFERE+LP   DAW+D  K
Sbjct  488  PQRDENGDIVYKKNGSKSV----DTNLRDTEDIPLTEDINEYFEREILPFNQDAWMDRKK  543

Query  632  VVRGYEISFTKYFYKF  647
               GYEI+FT+ FYK+
Sbjct  544  DKIGYEIPFTRLFYKY  559

108) Thimo_3451 in NC_019940


> NC_002953_R1|4|G3|49484939|YP_042160.1|Staphylococcus_aureus_subsp._aureus_MSSA476|-|4742..6529|-|SAS0027|type 
I restriction 
enzyme methylase
Length=595

 Score =  324 bits (1214),  Expect = 2e-89, Method: Compositional matrix adjust.
 Identities = 208/508 (41%), Positives = 336/508 (67%), Gaps = 32/508 (6%)

Query  1    MNTQTHEALKGKIWEIANRLRGPYRPPQYrlvmlpmvvlrrlDCVLEPTKDAVLRQLEKL  60
            +N Q +  L   IW++A+ LRG Y+P +Y  V+LPM V++RL+  L  T+D VL+  E  
Sbjct  12   INVQKQANL---IWNVADILRGLYKPHEYGKVILPMTVIKRLHDTLLKTRDKVLKTAE--  66

Query  61   EAQQMPQAAMDRLLGKAANPNRKHPLYNTSPYTFARLLGDAENIAPNLVSYINGFSPTAR  120
            ++Q + +   +RLL +A+      ++YNTS YTF  LL+D+ NI +N+ +Y+NGFS   +
Sbjct  67   NTQSINDVMRERLLKNASG----YSFYNTSLYTFETLLADPANIESNFRAYLNGFSENMQ  122

Query  121  RIFERFKFADQIEKLDASNRLFTIVKAMADVD--LHPERIDNLQMGYLFEHLVMRFNEQA  178
             I++ FKF  +I  +  ++ LF +++     D  L P+++ + +MGY+FE+LV +F+E  
Sbjct  123  DILNNFKFDVEITTMADNDVLFYVIQEFNKADAYLGPDKMTSTDMGYVFEELVRKFSESY  182

Query  179  NEEAGDHFTPREVIRLMANLIYTGEQD-VYKPGIYRTIYDPACGTGGMLSESEKLILSQN  237
            NEEAG HFT+R++I LM++L+   ++D ++K  +++T+YD + GT+ MLS     I   N
Sbjct  183  NEEAGAHFTSRDIIYLMTDLLLIEDKDTLFKEHVFKTVYDQTMGTSQMLSAMTERIHDMN  242

Query  238  ERAQLALHGQEYNDESWAICCSDMLIKDEDTSSIVLGDTLGDGKTRDGFEGKRFHYMLAN  297
            + A++A  GQE N E+ AI  +D +I++ D  ++ LG TL  ++    FEG  F+Y ++N
Sbjct  243  DTAEVATFGQELNPETYAISKADTMIRGGDPENMALGSTLTSDR----FEGFTFDYCISN  298

Query  298  PPFGVEWKDQKTQVENEHKTLGFSGRFGAGLPAINDGSLLFLQHMIAKMHPYQEGDEDRP  357
            PPFGV+WK ++  V  EH  LG  GRFG GLP ++DG LLF  + I+K+         + 
Sbjct  299  PPFGVDWKKDQKAVKAEHE-LGELGRFGVGLPRVSDGQLLFQLNGISKL---------KE  348

Query  358  GSKIAIVFNGSPLFSGDAGSGPSNIRRWIIENDWLDAIVALPDQLFYNTGIFTYVWLVTN  417
             +++AI+ NGS+LFSG++G+G S IR+ +IENDWL++I+ LP++LFYNTGI TY+W++T+
Sbjct  349  TGRMAIIHNGSALFSGNPGAGESLIRQYVIENDWLEGIIQLPNDLFYNTGISTYIWIITK  408

Query  418  RKPPERRGRVQLIDGTRFYQKMKKSLNNKRNEISEEQIRLLTQVYGNYRDGETAEVQING  477
             K+PER+G+VQL+D++  Y+K +K++ +KR +ISE    ++ Q YG++ D E        
Sbjct  409  DKSPERQGKVQLVDASNMYEKRRKNIGEKRVDISEACREMIVQAYGEFNDKEYY------  462

Query  478  QTETRVISRIFENREFGFLKITVERPLR  505
              +  V S+I+ N  FGF ++T+ERP R
Sbjct  463  LGDGTVESKILKNESFGFTRVTIERPQR  490


 Score = 67.6 bits (237),  Expect = 3e-12, Method: Compositional matrix adjust.
 Identities = 46/125 (37%), Positives = 65/125 (52%), Gaps = 25/125 (20%)

Query  601  ERDPEAEICRDSKGQPEPDSELRDTENIPLPPGTALPLQMDFGPDKPNDRLIVAFRDEID  660
            +RD +++I    +G    D++LRDTE+IPL                          ++I+
Sbjct  489  QRDENGDIVYKKNGSKSVDTNLRDTEDIPLT-------------------------EDIN  523

Query  661  AYVAREVLPHVPDAWVDYDKTKVGYEIPINRHFYVYKPPRPLEEIEADIVQLEEEIAGLL  720
             Y  RE+LP   DAW+D  K K+GYEIP+ R FY Y PP P E I   I QLEE I   +
Sbjct  524  EYFEREILPFNQDAWMDRKKDKIGYEIPFTRLFYKYTPPEPSEVISERIKQLEESIIKNF  583

Query  721  KGLVA  725
            ++L +
Sbjct  584  QALSG  588

109) Metme_4216 in NC_015572


> NC_002953_R1|4|G3|49484939|YP_042160.1|Staphylococcus_aureus_subsp._aureus_MSSA476|-|4742..6529|-|SAS0027|type 
I restriction 
enzyme methylase
Length=595

 Score =  322 bits (1209),  Expect = 4e-89, Method: Compositional matrix adjust.
 Identities = 207/503 (42%), Positives = 337/503 (67%), Gaps = 33/503 (6%)

Query  10   ANFIWSICNLLRGPYKRNEYRKVILPLTVLRRFDCLIAPSKDAAFEEFQSLKSKPERVIQ  69
            AN+IW++ ++LRG YK +EY KVILP+TV++R++  +  ++D  +   ++ +S  + + +
Sbjct  18   ANLIWNVADILRGLYKPHEYGKVILPMTVIKRLHDTLLKTRDKVLKTAENTQSINDVMRE  77

Query  70   ARLQTITGHRFYNLSRMQFDKNADHSilndpnnlapnlnnyinaFSPNVRAIMEKFKFSE  129
              L+  +G  FYN S   F+    ++   ++N  A         FS N++ I+++FKF  
Sbjct  78   RLLKNASGYSFYNTSLYTFETLLADPANIESNFRAYLNG-----FSENMQDILNNFKFDV  132

Query  130  QIAHMAEKNILFEVVKAFAAID--LSPQRVDNVQMGYVFEELIRIGAEQSNEEAGEHFTP  187
            +I+ MA++++LF V++ F   D  L+P+++ + +MGYVFEEL+R  +E  NEEAG HFT+
Sbjct  133  EITTMADNDVLFYVIQEFNKADAYLGPDKMTSTDMGYVFEELVRKFSESYNEEAGAHFTS  192

Query  188  REVIKLMVNLLLVPEQD-LAQSHVVKTIYDPACGTGGMLSVAEEYIRKLNADAQPKLFGQ  246
            R++I LM +LLL+ ++D L + HV KT+YD + GT+ MLS   E I+ +N  A+   FGQ
Sbjct  193  RDIIYLMTDLLLIEDKDTLFKEHVFKTVYDQTMGTSQMLSAMTERIHDMNDTAEVATFGQ  252

Query  247  DFNDEAWAVCKSDMLIKGEDADNVILGDTFTRDGFDRDNDGNKWTFDYMLANPPFGVEWK  306
            ++N E+ A+ K+D +I+G D++N+ LG T+T D F+        TFDY ++NPPFGV+WK
Sbjct  253  ELNPETYAISKADTMIRGGDPENMALGSTLTSDRFE------GFTFDYCISNPPFGVDWK  306

Query  307  QQQKHIQQETDTLGFAGRFGAGTPRINDGAFLFLQHMIAKMRPVSAGGSRIGIVFNGSPL  366
            ++QK ++ E + LG  GRFG G PR++DG +LF  + I+K++      +R++I+ NGS+L
Sbjct  307  KDQKAVKAEHE-LGELGRFGVGLPRVSDGQLLFQLNGISKLK----ETGRMAIIHNGSAL  361

Query  367  FTGDAGSGESEIRRWLIENDWLEAIVALPEQLFYNTGISTYIWIVSNRKEPQRKGKVQLI  426
            F+G++G+GES IR+ +IENDWLE+I+ LP++LFYNTGISTYIWI+++ K P+R+GKVQL+
Sbjct  362  FSGNPGAGESLIRQYVIENDWLEGIIQLPNDLFYNTGISTYIWIITKDKSPERQGKVQLV  421

Query  427  DARNFWVPMEKSLGNKRRRIGDPSDKAKDPDHIGDITRIYASFSDGETRLFTLDGKDKEL  486
            DA N      K++G+KR  I+++            I + Y+ F+D E   + L++     
Sbjct  422  DASNMYEKRRKNIGEKRVDISEACREM--------IVQAYGEFNDKE---YYLGD---GT  467

Query  487  VVNKLFDNEDFGYHKITVERPLR  509
            V +K++ NE FG+ ++T+ERP R
Sbjct  468  VESKILKNESFGFTRVTIERPQR  490


 Score = 97.8 bits (352),  Expect = 2e-21, Method: Compositional matrix adjust.
 Identities = 45/101 (45%), Positives = 72/101 (72%), Gaps = 0/101 (0%)

Query  606  SERDQTANICTDRQGNPEPDADLRDTETVPLKQSIDEYFQREVLPHVPDAWIDHSKTKVG  665
            ++RD+ ++I   ++G+   D++LRDTE +PL + I+EYF+RE+LP   DAW+D+ K K+G
Sbjct  488  PQRDENGDIVYKKNGSKSVDTNLRDTEDIPLTEDINEYFEREILPFNQDAWMDRKKDKIG  547

Query  666  YEIPLNRHFYRYEPPRALEVIEAEIKALEGEIVDLLREVTA  706
            YEIP+ R FY+Y PP + EVI   IK LE  I+  ++ +++
Sbjct  548  YEIPFTRLFYKYTPPEPSEVISERIKQLEESIIKNFQALSG  588

110) Mfla_2604 in NC_007947


> NC_002953_R1|4|G3|49484939|YP_042160.1|Staphylococcus_aureus_subsp._aureus_MSSA476|-|4742..6529|-|SAS0027|type 
I restriction 
enzyme methylase
Length=595

 Score =  321 bits (1205),  Expect = 9e-89, Method: Compositional matrix adjust.
 Identities = 216/513 (43%), Positives = 339/513 (67%), Gaps = 39/513 (7%)

Query  1    MNVHTHEVLKSTIWEIANRLRGPYRPPQYrlvmlpmvvlrrlDCVLEPTKDKVLKQYEKL  60
            +NV+ +  L   IW++A+ LRG Y+P +Y  V+LPM V++RL+  L  T+DKVLK  E+ 
Sbjct  12   INVQKQANL---IWNVADILRGLYKPHEYGKVILPMTVIKRLHDTLLKTRDKVLKTAEN-  67

Query  61   TAQNMPESAMERLLGRAADPKRNHPLYNTSPFTFERLLGDPENIAPNLVSYINGFSPTAR  120
             +Q++ +   ERLL  A+      ++YNTS +TFE LL+DP NI +N+ +Y+NGFS   +
Sbjct  68   -TQSINDVMRERLLKNAS----GYSFYNTSLYTFETLLADPANIESNFRAYLNGFSENMQ  122

Query  121  TIFERFKFTDQIEKLDASNRLFTIVKAMADVD--LHPDRIDNLQMGYLFEHLVMRFNEQA  178
             I++ FKF  +I  +  ++ LF +++     D  L PD++ + +MGY+FE+LV +F+E  
Sbjct  123  DILNNFKFDVEITTMADNDVLFYVIQEFNKADAYLGPDKMTSTDMGYVFEELVRKFSESY  182

Query  179  NEEAGDHFTPREVIRLMANLVYTGEKD-VYTPGIFRTIYDPACGTGGMLSESEKFILDQN  237
            NEEAG HFT+R++I LM++L+   +KD ++   +F+T+YD + GT+ MLS     I D N
Sbjct  183  NEEAGAHFTSRDIIYLMTDLLLIEDKDTLFKEHVFKTVYDQTMGTSQMLSAMTERIHDMN  242

Query  238  RQANLALFGQEYNDESWAICCSDMLIKDEDTSSIVLGDTLGDGKTRDGFEGEKFHYMLAN  297
              A++A FGQE N E+ AI  +D +I++ D  ++ LG TL  ++    FEG  F+Y ++N
Sbjct  243  DTAEVATFGQELNPETYAISKADTMIRGGDPENMALGSTLTSDR----FEGFTFDYCISN  298

Query  298  PPFGVEWKDQKTIVEKEHKELGFAGRFGAGLPAINDGSLLFLQHMISKMHPYKAGDENAV  357
            PPFGV+WK ++  V  EH ELG  GRFG GLP ++DG LLF  + ISK+           
Sbjct  299  PPFGVDWKKDQKAVKAEH-ELGELGRFGVGLPRVSDGQLLFQLNGISKLKE---------  348

Query  358  GSKIAIVFNGSPLFSGDAGSGPSNIRRWIIENDWLDAIVALPDQLFYNTGIYTYVWLVTN  417
             +++AI+ NGS+LFSG++G+G S IR+ +IENDWL++I+ LP++LFYNTGI TY+W++T+
Sbjct  349  TGRMAIIHNGSALFSGNPGAGESLIRQYVIENDWLEGIIQLPNDLFYNTGISTYIWIITK  408

Query  418  RKAPERRGKVQLIDGTRFCQRMKKSLNNKRHEITEDQIRELTRLYGNFRDGE--TAEVVI  475
             K+PER+GKVQL+D++   ++ +K++ +KR +I+E     + + YG+F D E   ++  +
Sbjct  409  DKSPERQGKVQLVDASNMYEKRRKNIGEKRVDISEACREMIVQAYGEFNDKEYYLGDGTV  468

Query  476  DHKTGEKETRVVSRIFENREFGFLKVTVERPLR  508
            +           S+I+ N  FGF +VT+ERP R
Sbjct  469  E-----------SKILKNESFGFTRVTIERPQR  490


 Score = 65.5 bits (229),  Expect = 1e-11, Method: Compositional matrix adjust.
 Identities = 43/123 (35%), Positives = 63/123 (52%), Gaps = 25/123 (20%)

Query  604  ERDPEAEICRDAKGRPEPDSELRDTENIPLPAGIVLPLPMDFGPDKPNDRLIESFRDVID  663
            +RD +++I    +G    D++LRDTE+IPL  +I                         +
Sbjct  489  QRDENGDIVYKKNGSKSVDTNLRDTEDIPLTEDI-------------------------N  523

Query  664  AYMAKEVLPHVPDAWVDYDKTKVGYEIPINRHFYVYKPPRPLQEIEADIRQLEGEIADLL  723
             Y  +E+LP   DAW+D  K K+GYEIP+ R FY Y PP P + I   I+QLE  I   +
Sbjct  524  EYFEREILPFNQDAWMDRKKDKIGYEIPFTRLFYKYTPPEPSEVISERIKQLEESIIKNF  583

Query  724  KGL  726
            ++L
Sbjct  584  QAL  586

111) CtCNB1_1525 in NC_013446


> NC_002953_R1|4|G3|49484939|YP_042160.1|Staphylococcus_aureus_subsp._aureus_MSSA476|-|4742..6529|-|SAS0027|type 
I restriction 
enzyme methylase
Length=595

 Score =  320 bits (1202),  Expect = 1e-88, Method: Compositional matrix adjust.
 Identities = 202/464 (44%), Positives = 318/464 (69%), Gaps = 42/464 (9%)

Query  7    NKIVSFIWSIADDCLRDVFVRGKYRDVILPMFVLRRLDCLLEPSKEAVLEEVRFQREDAE  66
            +K  ++IW++AD  LR+++    Y  VILPM V++RL+  L  +++ VL     +  ++ 
Sbjct  15   QKQANLIWNVAD-ILRGLYKPHEYGKVILPMTVIKRLHDTLLKTRDKVLKTA--ENTQSI  71

Query  67   MADLDPHGLREASGYVFYNTSRFTLKSLLGNPSQLEANLKNYLDGFSDNVKEIVEKFDLR  126
               +  + L++ASGY FYNTS +T+ +LL++P+++E+N++ YL+GFS+N+++I+++F + 
Sbjct  72   NDVMRERLLKNASGYSFYNTSLYTFETLLADPANIESNFRAYLNGFSENMQDILNNFKFD  131

Query  127  NQIRKMAQSDVLHDVIEKFVSDEINLSPNDRKGPDGRTQPGLSNLGMGYVFEELIRKFNE  186
             +I  MA++DVL  VI+ F   +  L+P+   + D           MGYVFEEL+RKF+E
Sbjct  132  VEITTMADNDVLFYVIQEFNKADAYLGPDKMTSTD-----------MGYVFEELVRKFSE  180

Query  187  ENNEEAGEHFTPREVIKLMTNLVFIPVKDQLPNPL---TIYDPACGSGGMLTESQDFITD  243
              NEEAG HFT+R++I LMT+L++I  KD L +     T+YD + G++ ML+     +T+
Sbjct  181  SYNEEAGAHFTSRDIIYLMTDLLLIEDKDTLFKEHVFKTVYDQTMGTSQMLSA----MTE  236

Query  244  PEGEIKAKVGVFLYGKEVNPETYAICKSDMMIKGNDPENIKFGSTLATDDFSGTRFDFML  303
               +++    V  +G+E+NPETYAI K+D MI+G DPEN+ +GSTL++D F G  FD+ +
Sbjct  237  RIHDMNDTAEVATFGQELNPETYAISKADTMIRGGDPENMALGSTLTSDRFEGFTFDYCI  296

Query  304  TNPPYGKSWKSDQKSIVEGKDVID-HRFQVNLSDYSEEDFDFYPAIPRSSDGQLLFMMEM  362
            +NPP+G  WK DQK++    ++ +  RF V L              PR SDGQLLF ++ 
Sbjct  297  SNPPFGVDWKKDQKAVKAEHELGELGRFGVGL--------------PRVSDGQLLFQLNG  342

Query  363  VGKMKRLGDSPMGSRIASVHNGSALFTGDAGSGESNIRRHIIENDYLEAIIQLPNNLFYN  422
            ++K+K  G      R+A +HNGSALF+G++G+GES IR+ +IEND LE+IIQLPN+LFYN
Sbjct  343  ISKLKETG------RMAIIHNGSALFSGNPGAGESLIRQYVIENDWLEGIIQLPNDLFYN  396

Query  423  TGITTYVWVLSNNKADQRKGKVQLIDASNLYQKLRKNLGEKNCE  466
            TGI+TY+W+++++K+ +R+GKVQL+DASN+Y+K RKN+GEK  +
Sbjct  397  TGISTYIWIITKDKSPERQGKVQLVDASNMYEKRRKNIGEKRVD  440

112) KVU_PA0074 in NC_017386


> NC_002953_R1|4|G3|49484939|YP_042160.1|Staphylococcus_aureus_subsp._aureus_MSSA476|-|4742..6529|-|SAS0027|type 
I restriction 
enzyme methylase
Length=595

 Score =  320 bits (1202),  Expect = 1e-88, Method: Compositional matrix adjust.
 Identities = 208/502 (42%), Positives = 333/502 (67%), Gaps = 40/502 (7%)

Query  8    ANLIWQIADLLRGPYRPPQYERVMLPLVVLRRFDCVLADTKQKVLAEFERRKGGKLEDDA  67
            ANLIW++AD+LRG Y+P +Y +V+LP+ V++R++  L  T++KVL   E  ++  ++D  
Sbjct  18   ANLIWNVADILRGLYKPHEYGKVILPMTVIKRLHDTLLKTRDKVLKTAENTQS--INDVM  75

Query  68   LDRMLNKASGHRFHNRSSMTFETMIGDTSDLVGHLQSYISGFSANVRRIFEYFEFTNEIE  127
             +R+L++ASG  F N S  TFET+++D +++ +++++Y++GFS N++ I++ F F  EI 
Sbjct  76   RERLLKNASGYSFYNTSLYTFETLLADPANIESNFRAYLNGFSENMQDILNNFKFDVEIT  135

Query  128  KMNEANILYLVLKEFLKVD--LHPDRVKNDQMGLVFENLIRRFNELANETAGDHFTPREV  185
             M + ++L+ V++EF K D  L PD++ + +MG VFE+L+R+F+E  NE AG HFT+R++
Sbjct  136  TMADNDVLFYVIQEFNKADAYLGPDKMTSTDMGYVFEELVRKFSESYNEEAGAHFTSRDI  195

Query  186  IHLMVDLLFMDADDVLSKPGTVMRMLDPACGTGGMLAEAQRYMRDHHKEAKLYVYGQDYN  245
            I LM DLL+++  D L K      + D + GT+ ML+     ++D +  A +  +GQ+ N
Sbjct  196  IYLMTDLLLIEDKDTLFKEHVFKTVYDQTMGTSQMLSAMTERIHDMNDTAEVATFGQELN  255

Query  246  KRAFATAASDMLMKQVDHNGGGENVQFGDSFTDDKFEGQTFDYFIANPPFGVDWKKQQKE  305
              ++A + +D +++     G+ EN+ +G ++T D+FEG TFDY I+NPPFGVDWKK+QK 
Sbjct  256  PETYAISKADTMIR----GGDPENMALGSTLTSDRFEGFTFDYCISNPPFGVDWKKDQKA  311

Query  306  IVRRHEKAPQDSPWSAGLPRVNDGSLLFLQHMISKFDDVDPKAQKYGSRAAIVFSGSPLF  365
            +   HE + + +  + GLPRV+DG LLF  + ISK+ +         +R AI+ +GS+LF
Sbjct  312  VKAEHELG-ELGRFGVGLPRVSDGQLLFQLNGISKLKET--------GRMAIIHNGSALF  362

Query  366  TGGAGGGESNIRKWIIERDMLEAIVALPEQMFYNTGIGTYIWIVTNNKPSHRKGDIQLVD  425
            +G +G+GES IR+ +IE D LE+I+ LP+++FYNTGI+TYIWI+T++K+++R+G +QLVD
Sbjct  363  SGNPGAGESLIRQYVIENDWLEGIIQLPNDLFYNTGISTYIWIITKDKSPERQGKVQLVD  422

Query  426  ARDIYMPMGRSQGDKRRKIGAGKAPEGDDRPDEPDQIAE-IVRLYGSFA--------PNS  476
            A ++Y        +KRRK        G+ R D ++   E IV+ YG F            
Sbjct  423  ASNMY--------EKRRK------NIGEKRVDISEACREMIVQAYGEFNDKEYYLGDGTV  468

Query  477  KSKIFDNAEFGYTRVTIERPLR  498
             SKI+ N  FG+TRVTIERP R
Sbjct  469  ESKILKNESFGFTRVTIERPQR  490


 Score = 79.4 bits (282),  Expect = 7e-16, Method: Compositional matrix adjust.
 Identities = 39/82 (48%), Positives = 56/82 (69%), Gaps = 0/82 (0%)

Query  585  ADPDLRDFENIPLKEDVDAYFAREVLPHVPDAWMDRSKDKVGYEINFNRHFYQFTTPRKL  644
             D +LRD E+IPL ED++ YF RE+LP   DAWMDR KDK+GYEI F R FY++T P   
Sbjct  506  VDTNLRDTEDIPLTEDINEYFEREILPFNQDAWMDRKKDKIGYEIPFTRLFYKYTPPEPS  565

Query  645  VEIDADLKKAEDEILRLLREVT  666
              I   +K+ E+ I++ ++ ++
Sbjct  566  EVISERIKQLEESIIKNFQALS  587

113) EIO_2897 in NC_014621


> NC_002953_R1|4|G3|49484939|YP_042160.1|Staphylococcus_aureus_subsp._aureus_MSSA476|-|4742..6529|-|SAS0027|type 
I restriction 
enzyme methylase
Length=595

 Score =  320 bits (1202),  Expect = 1e-88, Method: Compositional matrix adjust.
 Identities = 208/502 (42%), Positives = 333/502 (67%), Gaps = 40/502 (7%)

Query  8    ANLIWQIADLLRGPYRPPQYERVMLPLVVLRRFDCVLADTKQKVLAEFERRKGGKLEDDA  67
            ANLIW++AD+LRG Y+P +Y +V+LP+ V++R++  L  T++KVL   E  ++  ++D  
Sbjct  18   ANLIWNVADILRGLYKPHEYGKVILPMTVIKRLHDTLLKTRDKVLKTAENTQS--INDVM  75

Query  68   LDRMLNKASGHRFHNRSSMTFETMIGDTSDLVGHLQSYISGFSANVRRIFEYFEFTNEIE  127
             +R+L++ASG  F N S  TFET+++D +++ +++++Y++GFS N++ I++ F F  EI 
Sbjct  76   RERLLKNASGYSFYNTSLYTFETLLADPANIESNFRAYLNGFSENMQDILNNFKFDVEIT  135

Query  128  KMNEANILYLVLKEFLKVD--LHPDRVKNDQMGLVFENLIRRFNELANETAGDHFTPREV  185
             M + ++L+ V++EF K D  L PD++ + +MG VFE+L+R+F+E  NE AG HFT+R++
Sbjct  136  TMADNDVLFYVIQEFNKADAYLGPDKMTSTDMGYVFEELVRKFSESYNEEAGAHFTSRDI  195

Query  186  IHLMVDLLFMDADDVLSKPGTVMRMLDPACGTGGMLAEAQRYMRDHHKEAKLYVYGQDYN  245
            I LM DLL+++  D L K      + D + GT+ ML+     ++D +  A +  +GQ+ N
Sbjct  196  IYLMTDLLLIEDKDTLFKEHVFKTVYDQTMGTSQMLSAMTERIHDMNDTAEVATFGQELN  255

Query  246  KRAFATAASDMLMKQVDHNGGGENVQFGDSFTDDKFEGQTFDYFIANPPFGVDWKKQQKE  305
              ++A + +D +++     G+ EN+ +G ++T D+FEG TFDY I+NPPFGVDWKK+QK 
Sbjct  256  PETYAISKADTMIR----GGDPENMALGSTLTSDRFEGFTFDYCISNPPFGVDWKKDQKA  311

Query  306  IVRRHEKAPQDSPWSAGLPRVNDGSLLFLQHMISKFDDVDPKAQKYGSRAAIVFSGSPLF  365
            +   HE + + +  + GLPRV+DG LLF  + ISK+ +         +R AI+ +GS+LF
Sbjct  312  VKAEHELG-ELGRFGVGLPRVSDGQLLFQLNGISKLKET--------GRMAIIHNGSALF  362

Query  366  TGGAGGGESNIRKWIIERDMLEAIVALPEQMFYNTGIGTYIWIVTNNKPSHRKGDIQLVD  425
            +G +G+GES IR+ +IE D LE+I+ LP+++FYNTGI+TYIWI+T++K+++R+G +QLVD
Sbjct  363  SGNPGAGESLIRQYVIENDWLEGIIQLPNDLFYNTGISTYIWIITKDKSPERQGKVQLVD  422

Query  426  ARDIYMPMGRSQGDKRRKIGAGKAPEGDDRPDEPDQIAE-IVRLYGSFA--------PNS  476
            A ++Y        +KRRK        G+ R D ++   E IV+ YG F            
Sbjct  423  ASNMY--------EKRRK------NIGEKRVDISEACREMIVQAYGEFNDKEYYLGDGTV  468

Query  477  KSKIFDNAEFGYTRVTIERPLR  498
             SKI+ N  FG+TRVTIERP R
Sbjct  469  ESKILKNESFGFTRVTIERPQR  490


 Score = 79.4 bits (282),  Expect = 7e-16, Method: Compositional matrix adjust.
 Identities = 39/82 (48%), Positives = 56/82 (69%), Gaps = 0/82 (0%)

Query  585  ADPDLRDFENIPLKEDVDAYFAREVLPHVPDAWMDRSKDKVGYEINFNRHFYQFTTPRKL  644
             D +LRD E+IPL ED++ YF RE+LP   DAWMDR KDK+GYEI F R FY++T P   
Sbjct  506  VDTNLRDTEDIPLTEDINEYFEREILPFNQDAWMDRKKDKIGYEIPFTRLFYKYTPPEPS  565

Query  645  VEIDADLKKAEDEILRLLREVT  666
              I   +K+ E+ I++ ++ ++
Sbjct  566  EVISERIKQLEESIIKNFQALS  587

114) Despr_0254 in NC_014972


> NC_002953_R1|4|G3|49484939|YP_042160.1|Staphylococcus_aureus_subsp._aureus_MSSA476|-|4742..6529|-|SAS0027|type 
I restriction 
enzyme methylase
Length=595

 Score =  320 bits (1201),  Expect = 2e-88, Method: Compositional matrix adjust.
 Identities = 218/528 (42%), Positives = 346/528 (66%), Gaps = 59/528 (11%)

Query  10   ANFIWSICNLLRGPYKRNEYRKVILPLTVLRRFECLLEPTRQAALEEFQSLKTKPERVQQ  69
            AN+IW++ ++LRG YK +EY KVILP+TV++R++  L  TR+  L   ++ ++  + +++
Sbjct  18   ANLIWNVADILRGLYKPHEYGKVILPMTVIKRLHDTLLKTRDKVLKTAENTQSINDVMRE  77

Query  70   ARLQQITGHRFYNLSRMQL-TLPGEKIHSllddpnnlapnlnSYINGFSANVRAIMEKFK  128
              L++ +G  FYN S   + TL ++  +        + +N+ +Y+NGFS N++ I+++FK
Sbjct  78   RLLKNASGYSFYNTSLYTFETLLADPAN--------IESNFRAYLNGFSENMQDILNNFK  129

Query  129  FSEQIAHMAEKNILFEVIKAFAGID--LSPQRVDQMQMGYVFEELIRIGAEQSNEEAGEH  186
            F  +I+ MA++++LF VI+ F   D  L+P+++   +MGYVFEEL+R  +E  NEEAG H
Sbjct  130  FDVEITTMADNDVLFYVIQEFNKADAYLGPDKMTSTDMGYVFEELVRKFSESYNEEAGAH  189

Query  187  FTPREVIKLMVNLLLAPEQD-LAKSHVVKTIYDPACGTGGMLSVAEEYIRHLNSEAKPKV  245
            FT+R++I LM +LLL  ++D L K HV KT+YD + GT+ MLS   E I+++N  A    
Sbjct  190  FTSRDIIYLMTDLLLIEDKDTLFKEHVFKTVYDQTMGTSQMLSAMTERIHDMNDTAEVAT  249

Query  246  FGQDWNDEAWAVCKSDMLIKGEDANNIILGDSFTRDGFDRDSDGNKWTFDYMLANPPFGV  305
            FGQ+ N E+ A+ K+D +I+G D++N+ LG ++T D F+        TFDY ++NPPFGV
Sbjct  250  FGQELNPETYAISKADTMIRGGDPENMALGSTLTSDRFE------GFTFDYCISNPPFGV  303

Query  306  EWKQQQKTIQQEADTLGYAGRFGAGTPRINDGALLFLQHMIAKMRPVDKDGSRIAIVFNG  365
            +WK++QK+++ E + LG  GRFG G PR++DG LLF  + I+K+    K+ +R+AI+ NG
Sbjct  304  DWKKDQKAVKAEHE-LGELGRFGVGLPRVSDGQLLFQLNGISKL----KETGRMAIIHNG  358

Query  366  SPLFTGDAGSGESEIRRWIIENDWLEAIVALPEQLFYNTGIATYIWVITNRKAKERKGKI  425
            S+LF+G++G+GES IR+ +IENDWLE+I+ LP++LFYNTGI+TYIW+IT+ K+ ER+GK+
Sbjct  359  SALFSGNPGAGESLIRQYVIENDWLEGIIQLPNDLFYNTGISTYIWIITKDKSPERQGKV  418

Query  426  QLIDARNFWVQMEKSLGNKRRRIGdpndpnhprdpdYIADITRVYENFTDGESRWVVFDK  485
            QL+DA N   +  K++G+KR  I+++              I + Y +F D E        
Sbjct  419  QLVDASNMYEKRRKNIGEKRVDISEACREM----------IVQAYGEFNDKEY-------  461

Query  486  DSKVLGVNGLEPTVDDSNGQKKKYLVVSKLFDNEDFGYHKITVERPLR  533
                LG    + TV+            SK++ NE FG+ ++T+ERP R
Sbjct  462  ---YLG----DGTVE------------SKILKNESFGFTRVTIERPQR  490


 Score = 90.2 bits (323),  Expect = 4e-19, Method: Compositional matrix adjust.
 Identities = 46/100 (46%), Positives = 67/100 (67%), Gaps = 0/100 (0%)

Query  631  ERDETASICRDKQGNPEPDTDLRDTETVPLKEGVEEYFRREVLPHVPDAWIDHSKTKVGY  690
            +RDE + I   K+G+   DT+LRDTE +PL E+++EYF RE+LP   DAW+D+ K K+GY
Sbjct  489  QRDENGDIVYKKNGSKSVDTNLRDTEDIPLTEDINEYFEREILPFNQDAWMDRKKDKIGY  548

Query  691  EIPLNRHFYRYEPPRELAEIEAEIKVLEGEILDLLREVTA  730
            EIP+ R FY+Y PP     I   IK LE  I+  ++ +++
Sbjct  549  EIPFTRLFYKYTPPEPSEVISERIKQLEESIIKNFQALSG  588

115) Halhy_2185 in NC_015510


> NC_002953_R1|4|G3|49484939|YP_042160.1|Staphylococcus_aureus_subsp._aureus_MSSA476|-|4742..6529|-|SAS0027|type 
I restriction 
enzyme methylase
Length=595

 Score =  318 bits (1193),  Expect = 6e-88, Method: Compositional matrix adjust.
 Identities = 204/491 (42%), Positives = 328/491 (67%), Gaps = 28/491 (5%)

Query  7    HINLIWQIADLLRGPYRPPQYERVMLPMTVLRRFDCVLAPTKEAVLKEYQQLDSKYHGQD  66
            + NLIW++AD+LRG Y+P +Y +V+LPMTV++R++  L  T++ VLK       + ++ +
Sbjct  17   QANLIWNVADILRGLYKPHEYGKVILPMTVIKRLHDTLLKTRDKVLKT----AENTQSIN  72

Query  67   GVIDSRLNKISKQ-QFHNHSPLTFERLKGAPDSIAKDLVSYINGFSKNVrrifeyfefek  125
            +V+  RL K +    F N S  TFE L + P +I  ++ +Y+NGFS N++ I++ F F+ 
Sbjct  73   DVMRERLLKNASGYSFYNTSLYTFETLLADPANIESNFRAYLNGFSENMQDILNNFKFDV  132

Query  126  eierMNEANILYLVVSRFSTVD--LHPNAVSNTDMGKIFEHLIRKFNELANETAGDHFTP  183
            EI  M + ++L+ V+  F+  D  L P+ +++TDMG +FE+L+RKF+E  NE AG HFT+
Sbjct  133  EITTMADNDVLFYVIQEFNKADAYLGPDKMTSTDMGYVFEELVRKFSESYNEEAGAHFTS  192

Query  184  REVIRLMVNLLFINDDKLLTTPGTVRTMFDPACGTGGMLAEAQAYLREHHLEAKLYTYGQ  243
            R++I LM +LL+I+D   L      +T++D + GT+ ML+     +++ +  A + T+GQ
Sbjct  193  RDIIYLMTDLLLIEDKDTLFKEHVFKTVYDQTMGTSQMLSAMTERIHDMNDTAEVATFGQ  252

Query  244  DYNKRAFATAASDMLIKEVAHNGLGENIKFGDSLIEDQFKENKFDYLLSNPPFGVDWKKQ  303
            + N  ++A + +D +I+     G  EN+ +G +L  D+F    FDY +SNPPFGVDWKK+
Sbjct  253  ELNPETYAISKADTMIR----GGDPENMALGSTLTSDRFEGFTFDYCISNPPFGVDWKKD  308

Query  304  QSEITRENQKMGFAGRFGAGLPRVNDGALLFLQHMISKFEPVDEANRKYGSRLAIVFSGS  363
            Q  + + ++ +G  GRFG GLPRV+DG LLF  + ISK+           +R+AI+ +GS
Sbjct  309  QKAV-KAEHELGELGRFGVGLPRVSDGQLLFQLNGISKLKET--------GRMAIIHNGS  359

Query  364  PLFTGGAGSGESNIRRWIIENDWLEAVVSLPEQMFYNTGIGTYVWIVTNRKEKRRKGKIQ  423
            +LF+G +G+GES IR+ +IENDWLE+++ LP+++FYNTGI+TY+WI+T+ K   R+GK+Q
Sbjct  360  ALFSGNPGAGESLIRQYVIENDWLEGIIQLPNDLFYNTGISTYIWIITKDKSPERQGKVQ  419

Query  424  LLDARDFFVPMRRSLGDKRREIAEEQIVDIVQLYGRFEE--------TKHAKIFNNTDFG  475
            L+DA + +   R+++G+KR +I+E     IVQ YG F++        T ++KI++N  FG
Sbjct  420  LVDASNMYEKRRKNIGEKRVDISEACREMIVQAYGEFNDKEYYLGDGTVESKILKNESFG  479

Query  476  YTRVTVERPLR  486
            +TRVT+ERP R
Sbjct  480  FTRVTIERPQR  490


 Score = 75.7 bits (268),  Expect = 9e-15, Method: Compositional matrix adjust.
 Identities = 39/75 (52%), Positives = 53/75 (71%), Gaps = 0/75 (0%)

Query  553  TQRDPEAVPVLKSKNSYEPDSELRDFENIPLSEDVEKYFQREVLPHVPDAWIDRSKDKVG  612
             QRD ++  V K + S   D++LRD E+IPL+ED++ YF+RE+LP   DAW+DR KDK+G
Sbjct  488  PQRDENGDIVYKKNGSKSVDTNLRDTEDIPLTEDINEYFEREILPFNQDAWMDRKKDKIG  547

Query  613  YEINFNSHFYVFLPP  627
            YEI F   FY + PP
Sbjct  548  YEIPFTRLFYKYTPP  562

116) Dacet_1462 in NC_013943


> NC_002953_R1|4|G3|49484939|YP_042160.1|Staphylococcus_aureus_subsp._aureus_MSSA476|-|4742..6529|-|SAS0027|type 
I restriction 
enzyme methylase
Length=595

 Score =  317 bits (1190),  Expect = 1e-87, Method: Compositional matrix adjust.
 Identities = 199/476 (42%), Positives = 322/476 (68%), Gaps = 18/476 (3%)

Query  7    ANKIWSVADLLLGDFKQAEYGRIILPFMVLRRLECVLEPTRESVLEQYEAVKD-QGLDLD  65
            AN IW+VAD+L G +K  EYG++ILP  V++RL+  L  TR+ VL   E  +  +++  +
Sbjct  18   ANLIWNVADILRGLYKPHEYGKVILPMTVIKRLHDTLLKTRDKVLKTAENTQSINDVMRE  77

Query  66   LILPGIAGCTFYTTSKFTLSTL--GATNTKQNLEDYISKFSSNVRQVFEQFSFSSWIGKL  123
             +L   +G +FY TS +T+ TL  +++N   N+  Y++ FS N+++++++F F   I  +
Sbjct  78   RLLKNASGYSFYNTSLYTFETLLADPANIESNFRAYLNGFSENMQDILNNFKFDVEITTM  137

Query  124  EEANLLYLVSNEFKDLE--LHPSVVSNYEMGLVFEHLIRKFAEASNDTAGEFYTPRDVVR  181
             + ++L+ V +EF+  +  L P  +++ +MG VFE+L+RKF+E+ N+ AG  +T+RD++ 
Sbjct  138  ADNDVLFYVIQEFNKADAYLGPDKMTSTDMGYVFEELVRKFSESYNEEAGAHFTSRDIIY  197

Query  182  LATTLVFSTDQEALSGEGIVRTIYDCAAGTGGFLSSGIELVGEWNTNATIIPYAQELNPE  241
            L T L++  D+++L  E + +T+YD + GT+  LS+  E + + N  A +  ++QELNPE
Sbjct  198  LMTDLLLIEDKDTLFKEHVFKTVYDQTMGTSQMLSAMTERIHDMNDTAEVATFGQELNPE  257

Query  242  THAICVADKLIQGYDTRNIKFGNTLSNDLLSGETFNYCLANPPFGVDWKKVQKPVNDEHR  301
            T AI  AD +I+G D  N+ +G+TL++D + G TF+YC++NPPFGVDWKK QK+V+ EH 
Sbjct  258  TYAISKADTMIRGGDPENMALGSTLTSDRFEGFTFDYCISNPPFGVDWKKDQKAVKAEHE  317

Query  302  VKGYAGRFGPGLPRVSDGSMLFLLHLLSKRKPPEEGGTRIGIVLSGSPLFNGGAGSGESE  361
            + G  GRFG GLPRVSDG +LF L+ +SK K       R++I+ +GS+LF+G +G+GES 
Sbjct  318  L-GELGRFGVGLPRVSDGQLLFQLNGISKLK----ETGRMAIIHNGSALFSGNPGAGESL  372

Query  362  IRRWILENDWLEALVALPTDMFYNTGISTYIWVLSTNKEEHRKGLVQLIDASKISTPMRK  421
            IR+ ++ENDWLE+++ LP D+FYNTGISTYIW+++ +K  +R+G VQL+DAS++    RK
Sbjct  373  IRQYVIENDWLEGIIQLPNDLFYNTGISTYIWIITKDKSPERQGKVQLVDASNMYEKRRK  432

Query  422  NLGSKRKWLNDEQITETARIHDAFEESD--------VSKIFETEQFGYRRITVERP  469
            N+G KR  +++       +  + F++ +         SKI+  E FG+ R+T+ERP
Sbjct  433  NIGEKRVDISEACREMIVQAYGEFNDKEYYLGDGTVESKILKNESFGFTRVTIERP  488


 Score = 71.0 bits (250),  Expect = 2e-13, Method: Compositional matrix adjust.
 Identities = 39/95 (42%), Positives = 60/95 (64%), Gaps = 8/95 (8%)

Query  536  DAKVICDAKGNPLPDPDLRDYENVPLGEDIDEYFEREVIPHVPDAWIDTAKKDHKDGLVG  595
            ++ ++   +G+   D +LRD E++PL EDI+EYFERE++P   DAW+D  +K +K     
Sbjct  493  NGDIVYKKNGSKSVDTNLRDTEDIPLTEDINEYFEREILPFNQDAWMD--RKKDK-----  545

Query  596  IVGYEINFNRYFYEYVPPRSLEDIDADLEAVENAI  630
             +GYEI F R FY Y PP + E I   +  +E++I
Sbjct  546  -IGYEIPFTRLFYKYTPPEPSEVISERIKQLEESI  579

117) Dacet_1978 in NC_013943


> NC_002953_R1|4|G3|49484939|YP_042160.1|Staphylococcus_aureus_subsp._aureus_MSSA476|-|4742..6529|-|SAS0027|type 
I restriction 
enzyme methylase
Length=595

 Score =  317 bits (1190),  Expect = 1e-87, Method: Compositional matrix adjust.
 Identities = 199/476 (42%), Positives = 322/476 (68%), Gaps = 18/476 (3%)

Query  7    ANKIWSVADLLLGDFKQAEYGRIILPFMVLRRLECVLEPTRESVLEQYEAVKD-QGLDLD  65
            AN IW+VAD+L G +K  EYG++ILP  V++RL+  L  TR+ VL   E  +  +++  +
Sbjct  18   ANLIWNVADILRGLYKPHEYGKVILPMTVIKRLHDTLLKTRDKVLKTAENTQSINDVMRE  77

Query  66   LILPGIAGCTFYTTSKFTLSTL--GATNTKQNLEDYISKFSSNVRQVFEQFSFSSWIGKL  123
             +L   +G +FY TS +T+ TL  +++N   N+  Y++ FS N+++++++F F   I  +
Sbjct  78   RLLKNASGYSFYNTSLYTFETLLADPANIESNFRAYLNGFSENMQDILNNFKFDVEITTM  137

Query  124  EEANLLYLVSNEFKDLE--LHPSVVSNYEMGLVFEHLIRKFAEASNDTAGEFYTPRDVVR  181
             + ++L+ V +EF+  +  L P  +++ +MG VFE+L+RKF+E+ N+ AG  +T+RD++ 
Sbjct  138  ADNDVLFYVIQEFNKADAYLGPDKMTSTDMGYVFEELVRKFSESYNEEAGAHFTSRDIIY  197

Query  182  LATTLVFSTDQEALSGEGIVRTIYDCAAGTGGFLSSGIELVGEWNTNATIIPYAQELNPE  241
            L T L++  D+++L  E + +T+YD + GT+  LS+  E + + N  A +  ++QELNPE
Sbjct  198  LMTDLLLIEDKDTLFKEHVFKTVYDQTMGTSQMLSAMTERIHDMNDTAEVATFGQELNPE  257

Query  242  THAICVADKLIQGYDTRNIKFGNTLSNDLLSGETFNYCLANPPFGVDWKKVQKPVNDEHR  301
            T AI  AD +I+G D  N+ +G+TL++D + G TF+YC++NPPFGVDWKK QK+V+ EH 
Sbjct  258  TYAISKADTMIRGGDPENMALGSTLTSDRFEGFTFDYCISNPPFGVDWKKDQKAVKAEHE  317

Query  302  VKGYAGRFGPGLPRVSDGSMLFLLHLLSKRKPPEEGGTRIGIVLSGSPLFNGGAGSGESE  361
            + G  GRFG GLPRVSDG +LF L+ +SK K       R++I+ +GS+LF+G +G+GES 
Sbjct  318  L-GELGRFGVGLPRVSDGQLLFQLNGISKLK----ETGRMAIIHNGSALFSGNPGAGESL  372

Query  362  IRRWILENDWLEALVALPTDMFYNTGISTYIWVLSTNKEEHRKGLVQLIDASKISTPMRK  421
            IR+ ++ENDWLE+++ LP D+FYNTGISTYIW+++ +K  +R+G VQL+DAS++    RK
Sbjct  373  IRQYVIENDWLEGIIQLPNDLFYNTGISTYIWIITKDKSPERQGKVQLVDASNMYEKRRK  432

Query  422  NLGSKRKWLNDEQITETARIHDAFEESD--------VSKIFETEQFGYRRITVERP  469
            N+G KR  +++       +  + F++ +         SKI+  E FG+ R+T+ERP
Sbjct  433  NIGEKRVDISEACREMIVQAYGEFNDKEYYLGDGTVESKILKNESFGFTRVTIERP  488


 Score = 71.0 bits (250),  Expect = 2e-13, Method: Compositional matrix adjust.
 Identities = 39/95 (42%), Positives = 60/95 (64%), Gaps = 8/95 (8%)

Query  536  DAKVICDAKGNPLPDPDLRDYENVPLGEDIDEYFEREVIPHVPDAWIDTAKKDHKDGLVG  595
            ++ ++   +G+   D +LRD E++PL EDI+EYFERE++P   DAW+D  +K +K     
Sbjct  493  NGDIVYKKNGSKSVDTNLRDTEDIPLTEDINEYFEREILPFNQDAWMD--RKKDK-----  545

Query  596  IVGYEINFNRYFYEYVPPRSLEDIDADLEAVENAI  630
             +GYEI F R FY Y PP + E I   +  +E++I
Sbjct  546  -IGYEIPFTRLFYKYTPPEPSEVISERIKQLEESI  579

118) SHJG_7917 in NC_017765


> NC_002953_R1|4|G3|49484939|YP_042160.1|Staphylococcus_aureus_subsp._aureus_MSSA476|-|4742..6529|-|SAS0027|type 
I restriction 
enzyme methylase
Length=595

 Score =  316 bits (1184),  Expect = 4e-87, Method: Compositional matrix adjust.
 Identities = 196/478 (42%), Positives = 319/478 (67%), Gaps = 23/478 (4%)

Query  8    VWAIADTLRGVYARNKAGDVILPMTILRRLECVMAPHRAQV--AAIIAQQPNETLRVKMI  65
            +W +AD LRG+Y  +  G VILPMT+++RL+  +   R +V  +A  +Q  N+ +R +++
Sbjct  21   IWNVADILRGLYKPHEYGKVILPMTVIKRLHDTLLKTRDKVLKTAENTQSINDVMRERLL  80

Query  66   KSFTGGVKFYNTTKHTLASVYDSGDDMADNLLEYVRGFSKDI-DVFTYFHLPEHIERMRK  124
            K+ ++G  FYNT+  T+ ++     ++  N+  Y+ GFS ++ D++  F +  +I  M  
Sbjct  81   KN-ASGYSFYNTSLYTFETLLADPANIESNFRAYLNGFSENMQDILNNFKFDVEITTMAD  139

Query  125  GGILATIVRQFRDID--LSPESVPNSKMGELFEHLIYMDF-ESSNAESGDHYTPRDAINL  181
             ++L  ++++F   D  L+P+ + ++ MG +FE+L+   F ES N E+G H+T+RD I L
Sbjct  140  NDVLFYVIQEFNKADAYLGPDKMTSTDMGYVFEELV-RKFSESYNEEAGAHFTSRDIIYL  198

Query  182  LVDLLFAEDDKAL-SGEAIRSIYDPTVGTGGMLSVAEEHLHRMNPDAELLLYGQELRPES  240
            + DLL+ ED  +L   + ++++YD T+GT+ MLS   E++H MN  AE+  +GQEL PE+
Sbjct  199  MTDLLLIEDKDTLFKEHVFKTVYDQTMGTSQMLSAMTERIHDMNDTAEVATFGQELNPET  258

Query  241  YAMCRSDMLAKGQNPQNIVLGNTLTNDLFQDDRFDYILSNPPYGVDWKNIAEHVEREHKR  300
            YA+ ++D + +G +P+N+ LG+TLT+D F++  FDY +SNPP+GVDWK+    V  EH  
Sbjct  259  YAISKADTMIRGGDPENMALGSTLTSDRFEGFTFDYCISNPPFGVDWKKDQKAVKAEHEL  318

Query  301  GFSGRFGAGLPPTSDGALLFVQHAIAKMSPADSQDGGARAGIVLNGSPLFSGGAGSGSSN  360
            G  GRFG GLP  SDG LLF  ++I+K+  +      +R +I+ NGS+LFSG +G+G S 
Sbjct  319  GELGRFGVGLPRVSDGQLLFQLNGISKLKET------GRMAIIHNGSALFSGNPGAGESL  372

Query  361  IRGWLLENDLIEAIVALPNDMFYNTGIPTYLWIFDNNKRPERKGKVQLIDATDLGAKMRP  420
            IR  ++END +E+I+ LPND+FYNTGI+TY+WI+ ++K PER+GKVQL+DA+++  K R 
Sbjct  373  IRQYVIENDWLEGIIQLPNDLFYNTGISTYIWIITKDKSPERQGKVQLVDASNMYEKRRK  432

Query  421  SLGSKRVQIDEAARERVLQQYADMESSD--------TSKVFDNLDFAHWQITVERPLR  470
            ++G KRV+I EA RE ++Q Y++ +  +         SK++ N  F+  ++T+ERP R
Sbjct  433  NIGEKRVDISEACREMIVQAYGEFNDKEYYLGDGTVESKILKNESFGFTRVTIERPQR  490


 Score = 60.3 bits (209),  Expect = 4e-10, Method: Compositional matrix adjust.
 Identities = 44/117 (38%), Positives = 64/117 (55%), Gaps = 16/117 (13%)

Query  542  ERDENADICRFQSGKNKGQPEPDTSLRDTEIIPFGWDGHPKNHDAKDATIKAYFSAKVKP  601
            +RDEN+DI  +   K++G    DT+LRDTE IP+               I+ YF   + P
Sbjct  489  QRDENGDIV-Y---KKNGSKSVDTNLRDTEDIPLT------------EDINEYFEREILP  532

Query  602  HVDDAWVDYTKTKVGYEIPFTRHFYKYVPPRTLAEIDADLDQSLQDILGLLKKVEAR  658
              +DAW+D  K K+GYEIPFTR FYKY PP     I   + Q  + I+  ++ + ++
Sbjct  533  FNQDAWMDRKKDKIGYEIPFTRLFYKYTPPEPSEVISERIKQLEESIIKNFQALSGK  589

119) SHJGH_7679 in NC_020895


> NC_002953_R1|4|G3|49484939|YP_042160.1|Staphylococcus_aureus_subsp._aureus_MSSA476|-|4742..6529|-|SAS0027|type 
I restriction 
enzyme methylase
Length=595

 Score =  316 bits (1184),  Expect = 4e-87, Method: Compositional matrix adjust.
 Identities = 196/478 (42%), Positives = 319/478 (67%), Gaps = 23/478 (4%)

Query  8    VWAIADTLRGVYARNKAGDVILPMTILRRLECVMAPHRAQV--AAIIAQQPNETLRVKMI  65
            +W +AD LRG+Y  +  G VILPMT+++RL+  +   R +V  +A  +Q  N+ +R +++
Sbjct  21   IWNVADILRGLYKPHEYGKVILPMTVIKRLHDTLLKTRDKVLKTAENTQSINDVMRERLL  80

Query  66   KSFTGGVKFYNTTKHTLASVYDSGDDMADNLLEYVRGFSKDI-DVFTYFHLPEHIERMRK  124
            K+ ++G  FYNT+  T+ ++     ++  N+  Y+ GFS ++ D++  F +  +I  M  
Sbjct  81   KN-ASGYSFYNTSLYTFETLLADPANIESNFRAYLNGFSENMQDILNNFKFDVEITTMAD  139

Query  125  GGILATIVRQFRDID--LSPESVPNSKMGELFEHLIYMDF-ESSNAESGDHYTPRDAINL  181
             ++L  ++++F   D  L+P+ + ++ MG +FE+L+   F ES N E+G H+T+RD I L
Sbjct  140  NDVLFYVIQEFNKADAYLGPDKMTSTDMGYVFEELV-RKFSESYNEEAGAHFTSRDIIYL  198

Query  182  LVDLLFAEDDKAL-SGEAIRSIYDPTVGTGGMLSVAEEHLHRMNPDAELLLYGQELRPES  240
            + DLL+ ED  +L   + ++++YD T+GT+ MLS   E++H MN  AE+  +GQEL PE+
Sbjct  199  MTDLLLIEDKDTLFKEHVFKTVYDQTMGTSQMLSAMTERIHDMNDTAEVATFGQELNPET  258

Query  241  YAMCRSDMLAKGQNPQNIVLGNTLTNDLFQDDRFDYILSNPPYGVDWKNIAEHVEREHKR  300
            YA+ ++D + +G +P+N+ LG+TLT+D F++  FDY +SNPP+GVDWK+    V  EH  
Sbjct  259  YAISKADTMIRGGDPENMALGSTLTSDRFEGFTFDYCISNPPFGVDWKKDQKAVKAEHEL  318

Query  301  GFSGRFGAGLPPTSDGALLFVQHAIAKMSPADSQDGGARAGIVLNGSPLFSGGAGSGSSN  360
            G  GRFG GLP  SDG LLF  ++I+K+  +      +R +I+ NGS+LFSG +G+G S 
Sbjct  319  GELGRFGVGLPRVSDGQLLFQLNGISKLKET------GRMAIIHNGSALFSGNPGAGESL  372

Query  361  IRGWLLENDLIEAIVALPNDMFYNTGIPTYLWIFDNNKRPERKGKVQLIDATDLGAKMRP  420
            IR  ++END +E+I+ LPND+FYNTGI+TY+WI+ ++K PER+GKVQL+DA+++  K R 
Sbjct  373  IRQYVIENDWLEGIIQLPNDLFYNTGISTYIWIITKDKSPERQGKVQLVDASNMYEKRRK  432

Query  421  SLGSKRVQIDEAARERVLQQYADMESSD--------TSKVFDNLDFAHWQITVERPLR  470
            ++G KRV+I EA RE ++Q Y++ +  +         SK++ N  F+  ++T+ERP R
Sbjct  433  NIGEKRVDISEACREMIVQAYGEFNDKEYYLGDGTVESKILKNESFGFTRVTIERPQR  490


 Score = 60.3 bits (209),  Expect = 4e-10, Method: Compositional matrix adjust.
 Identities = 44/117 (38%), Positives = 64/117 (55%), Gaps = 16/117 (13%)

Query  542  ERDENADICRFQSGKNKGQPEPDTSLRDTEIIPFGWDGHPKNHDAKDATIKAYFSAKVKP  601
            +RDEN+DI  +   K++G    DT+LRDTE IP+               I+ YF   + P
Sbjct  489  QRDENGDIV-Y---KKNGSKSVDTNLRDTEDIPLT------------EDINEYFEREILP  532

Query  602  HVDDAWVDYTKTKVGYEIPFTRHFYKYVPPRTLAEIDADLDQSLQDILGLLKKVEAR  658
              +DAW+D  K K+GYEIPFTR FYKY PP     I   + Q  + I+  ++ + ++
Sbjct  533  FNQDAWMDRKKDKIGYEIPFTRLFYKYTPPEPSEVISERIKQLEESIIKNFQALSGK  589

120) lpa_00829 in NC_014125


> NC_002953_R1|4|G3|49484939|YP_042160.1|Staphylococcus_aureus_subsp._aureus_MSSA476|-|4742..6529|-|SAS0027|type 
I restriction 
enzyme methylase
Length=595

 Score =  315 bits (1180),  Expect = 8e-87, Method: Compositional matrix adjust.
 Identities = 213/498 (43%), Positives = 343/498 (69%), Gaps = 24/498 (4%)

Query  3    NENNKKIQNLSTFSWSIAEILRGDFKQSEYGKVILPFVVLRRLDCILETSKDAVVKAYEN  62
            ++ + ++Q+ + + W++A+ILRG +K  EYGKVILP  V++RL+  L  ++D V+K+ EN
Sbjct  8    QQTSINVQKQANLIWNVADILRGLYKPHEYGKVILPMTVIKRLHDTLLKTRDKVLKTAEN  67

Query  63   LPEGIDDHTKDMMLFSAVGGGLKVYNYNTLTFSKIRNQDPGDIHKNLLDYITSFNSSVRD  122
              ++I+D  ++ +L    ++G   YN +  TF  +   DP++I+ N+  Y+ +F+ +++D
Sbjct  68   -TQSINDVMRERLL--KNASGYSFYNTSLYTFETLLA-DPANIESNFRAYLNGFSENMQD  123

Query  123  IFLEKFLFTDQLKRLKDGGILWQVFDLFCQID--LHPDNVSNMEMGYLFEDLIRRFSEIS  180
            I L++F F  ++  + D ++L  V++ F + D  L PD++++ +MGY+FE+L+R+FSE  
Sbjct  124  I-LNNFKFDVEITTMADNDVLFYVIQEFNKADAYLGPDKMTSTDMGYVFEELVRKFSESY  182

Query  181  NETAGEHFTPREVIRlivdlllindadalaGSGIIRTVYDPACGTGGMLALMEEAMKEYN  240
            NE AG HFT+R++I L+ DLLLI+D D+L    +++TVYD + GT+ ML+ M E + + N
Sbjct  183  NEEAGAHFTSRDIIYLMTDLLLIEDKDTLFKEHVFKTVYDQTMGTSQMLSAMTERIHDMN  242

Query  241  SKIRVELYGQELNPESFGICTSDMLVTGHNPEQIAFGNTLTEDAHKDKKFHYMLSNPPYG  300
                V  +GQELNPE+++I  +D ++ G +PE++A+G+TLT D   +  F+Y +SNPP+G
Sbjct  243  DTAEVATFGQELNPETYAISKADTMIRGGDPENMALGSTLTSDRFEGFTFDYCISNPPFG  302

Query  301  VDWKKYQDPIKQEAQEKGMDGRFGAGLPRISDGQLLFLQHMISKMRDDEVGSRIGIVMNG  360
            VDWKK Q ++K E +E G  GRFG GLPR+SDGQLLF  + ISK+++    +R++I+ NG
Sbjct  303  VDWKKDQKAVKAE-HELGELGRFGVGLPRVSDGQLLFQLNGISKLKE---TGRMAIIHNG  358

Query  361  SPLFTGGAGSGESEIRRWMLENDWVEAIIALPTDLFYNTGIQTYVWMLTNKKDKNRRGKV  420
            S+LF+G +G+GES IR+ ++ENDW+E+II LP DLFYNTGI TY+W++T+ K  +R+GKV
Sbjct  359  SALFSGNPGAGESLIRQYVIENDWLEGIIQLPNDLFYNTGISTYIWIITKDKSPERQGKV  418

Query  421  QLIDASSERFWQSMRKSLGSKRREISDHARSEIVKIY-------YEMLNGGGDWSEFSKI  473
            QL+DAS+    +  RK++G KR +IS+  R  IV+ Y       Y + +G  +    SKI
Sbjct  419  QLVDASN--MYEKRRKNIGEKRVDISEACREMIVQAYGEFNDKEYYLGDGTVE----SKI  472

Query  474  FDRQEFGYREIRIERPLR  491
            +  + FG+  + IERP R
Sbjct  473  LKNESFGFTRVTIERPQR  490


 Score = 77.3 bits (274),  Expect = 3e-15, Method: Compositional matrix adjust.
 Identities = 44/102 (44%), Positives = 62/102 (61%), Gaps = 8/102 (7%)

Query  568  SEKDETADVCCDAKGNPEPDTDLRDHELVPLKEDWREYVEREVKPFVANAWVDENHKDAT  627
            +++DE +D+    +G+   DT+LRD E +PL ED  EY ERE+ PF  +AW+D       
Sbjct  488  PQRDENGDIVYKKNGSKSVDTNLRDTEDIPLTEDINEYFEREILPFNQDAWMDR------  541

Query  628  DGKVGRVGYEINFNRYFYRYVPPRPVAEIDEELKQLESEIAN  669
              K +++GYEI F R FY+Y PP P   I E +KQLE  I +
Sbjct  542  --KKDKIGYEIPFTRLFYKYTPPEPSEVISERIKQLEESIIK  581

121) SCIM_1266 in NC_018073


> NC_002953_R1|4|G3|49484939|YP_042160.1|Staphylococcus_aureus_subsp._aureus_MSSA476|-|4742..6529|-|SAS0027|type 
I restriction 
enzyme methylase
Length=595

 Score =  313 bits (1175),  Expect = 2e-86, Method: Compositional matrix adjust.
 Identities = 206/504 (41%), Positives = 322/504 (64%), Gaps = 33/504 (6%)

Query  1    MSNFKNKLPLFQGNSVNISKDVNLVWSIANTLRGAYRADKYRDVIIPMFVLARLEAALLP  60
            MS+FK      Q  S+N+ K+ NL+W++A+ LRG Y+++ Y  VI+PM V+ RL+ +LL 
Sbjct  1    MSEFKRH----QQTSINVQKQANLIWNVADILRGLYKPHEYGKVILPMTVIKRLHDTLLK  56

Query  61   TKEKVLEQYKANPKTP----ERIYESITGYKYYNLSQFTLKNLLNDPDGIKENFLDYLDG  116
            T++KVL              ER+  + +GY +YN S +T+  LL DP  I  NF  YL+G
Sbjct  57   TRDKVLKTAENTQSINDVMRERLLKNASGYSFYNTSLYTFETLLADPANIESNFRAYLNG  116

Query  117  YSQRVKDIIENLKFKDEVETLAKTGRLFTVVKKFSEID--LSTSTVDSMRMGYMFEDIIR  174
            +S+ ++DI++N+KF  E+ T+A  + LF V++ F+  D  L+   + S  MGY+FE+++R
Sbjct  117  FSENMQDILNNFKFDVEITTMADNDVLFYVIQEFNKADAYLGPDKMTSTDMGYVFEELVR  176

Query  175  RFSE--NEEAGSHYTPREVIGLMVNLLLMEADESLFKAGKEIKILDmaagtggmlataQS  232
            +FSE  NEEAG+H+T+R++I LM +LLL+E  ++LFK      + D + GT+ ML++   
Sbjct  177  KFSESYNEEAGAHFTSRDIIYLMTDLLLIEDKDTLFKEHVFKTVYDQTMGTSQMLSAMTE  236

Query  233  YIKQLNHDVSVRLFGQEYLSETYGIGKADMLFRQEESDYFVKADTLKDPDSFPDVKMNFV  292
             I ++N+   V  FGQE  +ETY+I+KAD ++R  +++    + TL  +D F +   ++ 
Sbjct  237  RIHDMNDTAEVATFGQELNPETYAISKADTMIRGGDPENMALGSTLT-SDRFEGFTFDYC  295

Query  293  IANPPFGQSWGGKDADDGVEAAVKKDQELFEKTEGREGRF-VATPTTGDAQLLFHLHALA  351
            I+NPPFG  W         + AVK ++EL     G  GRF V+ P  +D+QLLF+L++++
Sbjct  296  ISNPPFGVDWKKD------QKAVKAEHEL-----GELGRFGVGLPRVSDGQLLFQLNGIS  344

Query  352  KMEENGRAAIISNGSPLFSGGTTSGESQIRRYILENDLLEAIIALPGQFFYNTGIGIYIW  411
            K+ E GR AII NGS+LFSG   +GES IR+Y++END LE+II LP ++FYNTGI+ YIW
Sbjct  345  KLKETGRMAIIHNGSALFSGNPGAGESLIRQYVIENDWLEGIIQLPNDLFYNTGISTYIW  404

Query  412  IYNKDKKPERQNKVQFIDATGEFVPLRKSLGQKRRELSPDNIRQIVKWYHDFKENE----  467
            I  KDK PERQ KVQ++DA+  +   RK++G+KR ++S      IV+ Y +F+++E    
Sbjct  405  IITKDKSPERQGKVQLVDASNMYEKRRKNIGEKRVDISEACREMIVQAYGEFNDKEYYLG  464

Query  468  ----QVKIFDNQEFLYKEFLVMQP  487
                + KI+ N+ F +    + +P
Sbjct  465  DGTVESKILKNESFGFTRVTIERP  488


 Score = 48.2 bits (163),  Expect = 2e-06, Method: Compositional matrix adjust.
 Identities = 30/62 (49%), Positives = 40/62 (65%), Gaps = 4/62 (6%)

Query  619  DKTTKDSEIVKLSEDESTYFEREVYPHVPDAHYW--WDDTKLGAEIPFTRYFYKYQAPEK  676
            D   +D+E + L+ED + YFERE+ P   DA  W  +   K+G EIPFTR FYKY +PE 
Sbjct  507  DTNLRDTEDIPLTEDINEYFEREILPFNQDA--WMDRKKDKIGYEIPFTRLFYKYTPPEP  564

Query  677  AE  678
            +E
Sbjct  565  SE  566

122) SPPN_09370 in NC_015875


> NC_002953_R1|4|G3|49484939|YP_042160.1|Staphylococcus_aureus_subsp._aureus_MSSA476|-|4742..6529|-|SAS0027|type 
I restriction 
enzyme methylase
Length=595

 Score =  312 bits (1169),  Expect = 6e-86, Method: Compositional matrix adjust.
 Identities = 207/504 (42%), Positives = 332/504 (66%), Gaps = 33/504 (6%)

Query  1    MSNFKEKLPLFQANDIQISNDVNTVWSIANTLRGAYRADKYRDVIIPMFVLTRLEAALLP  60
            MS+FK      Q   I++ ++ N +W++A+ LRG Y+++ Y  VI+PM V+ RL+ +LL 
Sbjct  1    MSEFKRH----QQTSINVQKQANLIWNVADILRGLYKPHEYGKVILPMTVIKRLHDTLLK  56

Query  61   TKDQVVAQYKANPNTP----EKVLEKLSGYRYYNVSPFTLENLQNDPNAIEENFLAYLDG  116
            T+D+V+       +      E++L + SGY +YN S +T+E L  DP  IE NF AYL+G
Sbjct  57   TRDKVLKTAENTQSINDVMRERLLKNASGYSFYNTSLYTFETLLADPANIESNFRAYLNG  116

Query  117  YSYRVKDIIENLKFKEQVRTLAQSGRLFTVIKKFSQID--LSPSSVDSMRMGYMFEDIIR  174
            +S  ++DI++N+KF  ++ T+A+++ LF VI+ F++ D  L+P  + S  MGY+FE+++R
Sbjct  117  FSENMQDILNNFKFDVEITTMADNDVLFYVIQEFNKADAYLGPDKMTSTDMGYVFEELVR  176

Query  175  RFSE--NEEAGSHYTPREVIALMVNLLLIEADEELFVDKKELKILDmaagtggmlataKS  232
            +FSE  NEEAG+H+T+R++I LM +LLLIE  + LF +     + D + GT+ ML++   
Sbjct  177  KFSESYNEEAGAHFTSRDIIYLMTDLLLIEDKDTLFKEHVFKTVYDQTMGTSQMLSAMTE  236

Query  233  YIRQLNTGVTVRLFGQEVLPETFGIGRADMLIRQEDSDYFVKVDTLKDPDPFPDTKMSFV  292
             I+++N    V  FGQE+ PET++I++AD +IR  D++      TL  +D F +    + 
Sbjct  237  RIHDMNDTAEVATFGQELNPETYAISKADTMIRGGDPENMALGSTLT-SDRFEGFTFDYC  295

Query  293  IANPPFGQAWGGKDADDGVEDAVKKDHQLFDKTEGRQGRF-VATPGTGDAQLLFHLHALA  351
            I+NPPFG  W  KD     + AVK +H+L     G  GRF V+ P  +D+QLLF+L++++
Sbjct  296  ISNPPFGVDWK-KD-----QKAVKAEHEL-----GELGRFGVGLPRVSDGQLLFQLNGIS  344

Query  352  KLEENGRAAIISNGSPLFSGGTSSGESQIRRYILENDLLEAIVALPGQFFYNTGIGIYIW  411
            KL E GR AII NGS+LFSG  ++GES IR+Y++END LE+I+ LP ++FYNTGI+ YIW
Sbjct  345  KLKETGRMAIIHNGSALFSGNPGAGESLIRQYVIENDWLEGIIQLPNDLFYNTGISTYIW  404

Query  412  IYNKNKSLERQNKVQFIDAAEEFVPLRKSLGQKRRELSQDNIRQILRWYDDFQEND----  467
            I  K+KS ERQ KVQ++DA++ +   RK++G+KR ++S+     I++ Y++F++++    
Sbjct  405  IITKDKSPERQGKVQLVDASNMYEKRRKNIGEKRVDISEACREMIVQAYGEFNDKEYYLG  464

Query  468  ----HVKIFDNQEFLYREFTVMQP  487
                + KI+ N+ F +   T+ +P
Sbjct  465  DGTVESKILKNESFGFTRVTIERP  488


 Score = 48.4 bits (164),  Expect = 2e-06, Method: Compositional matrix adjust.
 Identities = 31/84 (37%), Positives = 51/84 (61%), Gaps = 6/84 (7%)

Query  600  VIRTKRKDKANEI---ADGIVYDKTTKDSEIVKLTEDVETYFAREVYPHVPDAHYWFDEE  656
            + R +R ++++ +    ++   D   +D+E + LTED++ YF RE+ P   DA  W D  
Sbjct  485  IERPQRDENGDIVYKKNGSKSVDTNLRDTEDIPLTEDINEYFEREILPFNQDA--WMDRK  542

Query  657  KG-YGAEIPFTRYFYHYQAPESAD  679
            K+  G EIPFTR FY Y +PE+++
Sbjct  543  KDKIGYEIPFTRLFYKYTPPEPSE  566

123) Mhar_1859 in NC_017527


> NC_002953_R1|4|G3|49484939|YP_042160.1|Staphylococcus_aureus_subsp._aureus_MSSA476|-|4742..6529|-|SAS0027|type 
I restriction 
enzyme methylase
Length=595

 Score =  309 bits (1157),  Expect = 6e-85, Method: Compositional matrix adjust.
 Identities = 207/507 (41%), Positives = 329/507 (65%), Gaps = 45/507 (8%)

Query  10   TNFIWGIADDVLRDIYVRGKYRDVILPMTVIRRLDAVLEPTKQSVLDLKKQLDEAGITNQ  69
            +N+IW +AD +LR++Y    Y  VILPMTVI+RL+  L  T++ VL    + +      +
Sbjct  18   ANLIWNVAD-ILRGLYKPHEYGKVILPMTVIKRLHDTLLKTRDKVLKTAENTQSINDVMR  76

Query  70   DAALRQASGQAFYNTSPFLLRDLKARPKAQQLKADLEAYLDGFSPNVQDILDKFKFRNQI  129
            +  L++ASG +FYNTS + +  L A P   ++ +++ AYL+GFS N+QDIL++FKF  +I
Sbjct  77   ERLLKNASGYSFYNTSLYTFETLLADP--ANIESNFRAYLNGFSENMQDILNNFKFDVEI  134

Query  130  PTLVEADILGYLIEKFLDNSINLSPNPIYDPAGNVRLPPLDNHAIGTIFEELIRRFNEEN  189
             T+ + D+L Y+I+ F      L+P+             + +  +G +FEEL+R+F+E  
Sbjct  135  TTMADNDVLFYVIQEFNKADAYLGPDK------------MTSTDMGYVFEELVRKFSESY  182

Query  190  NEEAGEHFTPRDVVRLMADLVILPIADKI-ESATY-LLYDGACGTGGMLTIADERLKQIA  247
            NEEAG HFT+RD++ LM+DL+++   D +     +  +YD + GT+ ML+   ER+ ++ 
Sbjct  183  NEEAGAHFTSRDIIYLMTDLLLIEDKDTLFKEHVFKTVYDQTMGTSQMLSAMTERIHDMN  242

Query  248  QEHGKDVSIHLFGQEVNPETYAITKADLLIKGEGDEAEYFFLGSTLSQDAFASREFDFML  307
            +       +  FGQE+NPETYAI+KAD +I+G  +++E   LGSTL+ D F +  FD+ +
Sbjct  243  D----TAEVATFGQELNPETYAISKADTMIRG--GDPENMALGSTLTSDRFEGFTFDYCI  296

Query  308  SNPPYGKSWKADMERMGGKADILDL-RFVIEHAGDPDFKLITRSSDGQMMFLVNMLSKMK  366
            SNPP+G  WK D   + +  ++ +L RF +          + R SDGQ++F +N +SK+K
Sbjct  297  SNPPFGVDWKKDQKAVKAEHELGELGRFGVG---------LPRVSDGQLLFQLNGISKLK  347

Query  367  HQTPLGSRIAEVHNGSSLFTGDAGQGESNIRRWIIENDWLEAIIALPLNMFYNTGIATYI  426
            +     +R+A +HNGS+LF+G++G GES IR+ +IENDWLE+II LP ++FYNTGI+TYI
Sbjct  348  E----TGRMAIIHNGSALFSGNPGAGESLIRQYVIENDWLEGIIQLPNDLFYNTGISTYI  403

Query  427  WVLTNRKPDHRKGKVQLIDATSWFKPLRKNLGKKNCELSAEDIQRIVDLFLSFQESE---  483
            W++T+ K+ +R+GKVQL+DA++ +   RKN+G K  ++S    + IV+ +  F++ E   
Sbjct  404  WIITKDKSPERQGKVQLVDASNMYEKRRKNIGEKRVDISEACREMIVQAYGEFNDKEYYL  463

Query  484  -----QSKIFANESFGFSKVTVERPLR  505
                 +SKI+ NESFGF++VT+ERP R
Sbjct  464  GDGTVESKILKNESFGFTRVTIERPQR  490


 Score = 63.4 bits (221),  Expect = 5e-11, Method: Compositional matrix adjust.
 Identities = 40/89 (45%), Positives = 53/89 (60%), Gaps = 2/89 (2%)

Query  623  ADSELRDVEQVPLLEEGGIEAFFLREVLPHVPDAWIDETSAKIGYEISFTRYFYKPTPLR  682
             D++LRD E++PL E+  I+ +F RE+LP   DAW+D    KIGYEI+FTR FYK TP  
Sbjct  506  VDTNLRDTEDIPLTED--INEYFEREILPFNQDAWMDRKKDKIGYEIPFTRLFYKYTPPE  563

Query  683  TLEEIRADILSLEKETEGLLDEIIGGEVS  711
              E I   I  LE      ++ + G EV 
Sbjct  564  PSEVISERIKQLEESIIKNFQALSGKEVD  592

124) Cbei_3161 in NC_009617


> NC_002953_R1|4|G3|49484939|YP_042160.1|Staphylococcus_aureus_subsp._aureus_MSSA476|-|4742..6529|-|SAS0027|type 
I restriction 
enzyme methylase
Length=595

 Score =  304 bits (1140),  Expect = 1e-83, Method: Compositional matrix adjust.
 Identities = 205/484 (43%), Positives = 320/484 (67%), Gaps = 24/484 (4%)

Query  8    VSFLWNIAESLRGTYKEEDYRKVMIPMIVVRRF-DCLLDDYDKEIIKKVYSNYDYMPEEE  66
             +++WN+A+ LRG YK ++Y KV++PM V++R+ D LL   DK ++K           + 
Sbjct  18   ANLIWNVADILRGLYKPHEYGKVILPMTVIKRLHDTLLKTRDK-VLKTA------ENTQS  70

Query  67   IDEIVIADLKENHNIDLQFYNVSDFTWKKLLDDSENIKANFEEYLNGFSNNVKEIIGKFN  126
            I++++   L  ++  +  FYN S +T   LL D+ NI +NF  YLNGFS+N+++I+ +F+
Sbjct  71   INDVMRERLL-KNASGYSFYNTSLYTFETLLADPANIESNFRAYLNGFSENMQDILNNFK  129

Query  127  FKAEITQLDKKNKLYAVLQKMSEVD--LHINKISNNKMGYIYEEMLRRFTE--NSAAGEQ  182
            F  EIT +  ++ L+ V+Q  +  D  L  +K+++  MGY++EE++R+F+E  N  AG +
Sbjct  130  FDVEITTMADNDVLFYVIQEFNKADAYLGPDKMTSTDMGYVFEELVRKFSESYNEEAGAH  189

Query  183  YTPREVIKLCMEMLFLGKESFITEEGKVISIADFCCGTGGMLSIAEAYVENLNEKAIVDV  242
            +T+R++I L  ++L++     +  E    ++ D   GT+ MLS     ++++N+ A V  
Sbjct  190  FTSRDIIYLMTDLLLIEDKDTLFKEHVFKTVYDQTMGTSQMLSAMTERIHDMNDTAEVAT  249

Query  243  YGQELLDESFAICQADMLMKGQNPDNIRLGNTLTEDRFSGEHMRFLISNPPFGVTWkdee  302
            +GQEL  E++AI +AD +++G +P+N+ LG+TLT DRF G    + ISNPPFGV WK ++
Sbjct  250  FGQELNPETYAISKADTMIRGGDPENMALGSTLTSDRFEGFTFDYCISNPPFGVDWKKDQ  309

Query  303  kkvkdeadLGFDGRFGAGTPRVSDGSLLFLQNMISKMYDDEEGSRIAIIFNGSPLFTGDA  362
            K VK E +LG  GRFG G PRVSDG LLF  N ISK+    E +R+AII NGS+LF+G++
Sbjct  310  KAVKAEHELGELGRFGVGLPRVSDGQLLFQLNGISKL---KETGRMAIIHNGSALFSGNP  366

Query  363  GSGESNIRRWIIENDMLEGIIALPTDMFYNTGIATYIWVITNRKTENRKGKIQLVNATDF  422
            G+GES IR+ +IEND LEGII LP D+FYNTGI+TYIW+IT+ K+ +R+GK+QLV+A++ 
Sbjct  367  GAGESLIRQYVIENDWLEGIIQLPNDLFYNTGISTYIWIITKDKSPERQGKVQLVDASNM  426

Query  423  YVPMRKSLGNKRKEISTEQIQEIKSIYESFEPSE--------NCRIFDNKEFGYRKITIE  474
            Y   RK++G+KR +IS    + I   Y  F+  E        + +I+ N  FG+ ++TIE
Sbjct  427  YEKRRKNIGEKRVDISEACREMIVQAYGEFNDKEYYLGDGTVESKILKNESFGFTRVTIE  486

Query  475  RPLK  478
            RP +
Sbjct  487  RPQR  490


 Score = 67.1 bits (235),  Expect = 4e-12, Method: Compositional matrix adjust.
 Identities = 43/92 (47%), Positives = 58/92 (64%), Gaps = 1/92 (1%)

Query  573  ERNEDADICKDSKGNPESDSSLKDTESIQLKEDINAYFEREVKPHVPDAYMDETTFSNIG  632
            +R+E++DI    +G+   D++L+DTE I L EDIN YFERE+ P   DA MD     +IG
Sbjct  489  QRDENGDIVYKKNGSKSVDTNLRDTEDIPLTEDINEYFEREILPFNQDAWMDRKK-DKIG  547

Query  633  YEIPFTRHFYKYEKLRAFSDIMKEVEDLEQEI  664
            YEIPFTR FYKY    +   I   + +LE+ I
Sbjct  548  YEIPFTRLFYKYTPPEPSEVISERIKQLEESI  579

125) Dde_1861 in NC_007519


> NC_002953_R1|4|G3|49484939|YP_042160.1|Staphylococcus_aureus_subsp._aureus_MSSA476|-|4742..6529|-|SAS0027|type 
I restriction 
enzyme methylase
Length=595

 Score =  300 bits (1124),  Expect = 2e-82, Method: Compositional matrix adjust.
 Identities = 207/507 (41%), Positives = 325/507 (65%), Gaps = 45/507 (8%)

Query  10   VNFIWGIADDVLRDVYVRGKYRDVILPMTVIRRLDALLEPSKEKVLGMKKQLDGAGIANQ  69
             N+IW +AD +LR++Y    Y  VILPMTVI+RL+  L  +++KVL    + ++     +
Sbjct  18   ANLIWNVAD-ILRGLYKPHEYGKVILPMTVIKRLHDTLLKTRDKVLKTAENTQSINDVMR  76

Query  70   HAALCQAAGEAFYNVSPFTLRDLKNRAKQQQLKADFEAYLDGFSPNVQEILDKFKFRNQI  129
            +  L +A+G +FYN S +T+  L   A   ++ ++F AYL+GFS N+Q+IL++FKF  +I
Sbjct  77   ERLLKNASGYSFYNTSLYTFETLL--ADPANIESNFRAYLNGFSENMQDILNNFKFDVEI  134

Query  130  PTLIEADILGHLIEKFLDGRVNLSPKPVRDVDGNELLPALDNHSMGTIFEELIRRFNEEN  189
             T+ + D+L  +I+ F  +   L+P  +   D            MG +FEEL+R+F+E  
Sbjct  135  TTMADNDVLFYVIQEFNKADAYLGPDKMTSTD------------MGYVFEELVRKFSESY  182

Query  190  NEEAGEHFTPRDVVKLMADLIFLPVADDI-ESGTY-LVYDGACGTGGMLTVAEERLAELA  247
            NEEAG HFT+RD++ LM+DL+++   D +     +  VYD + GT+ ML+   ER+ ++ 
Sbjct  183  NEEAGAHFTSRDIIYLMTDLLLIEDKDTLFKEHVFKTVYDQTMGTSQMLSAMTERIHDMN  242

Query  248  ESHGKDVSIHLFGQEVQPETYAISKADLLLKGEGAEAENMKYGSTLSSDAFPSQEFDFML  307
            ++      +  FGQE++PETYAISKAD +++G  +++ENM  GSTL+SD F +  FD+ +
Sbjct  243  DT----AEVATFGQELNPETYAISKADTMIRG--GDPENMALGSTLTSDRFEGFTFDYCI  296

Query  308  SNPPYGKSWKTDLERLGGKGDIKD-PRFVTQHANDSEYKMITRSSDGQLMFLVNKLSKMK  366
            SNPP+G  WK D   + +  ++ +  RF            + R SDGQL+F +N +SK+K
Sbjct  297  SNPPFGVDWKKDQKAVKAEHELGELGRFGVG---------LPRVSDGQLLFQLNGISKLK  347

Query  367  HSTKLGSRIAEVHNGSSLFTGDAGQGESNIRRWIIENDWLEAIIALPENMFYNTGIATYI  426
            ++    +R+A +HNGS+LF+G++G GES IR+ +IENDWLE+II LP+++FYNTGI+TYI
Sbjct  348  ET----GRMAIIHNGSALFSGNPGAGESLIRQYVIENDWLEGIIQLPNDLFYNTGISTYI  403

Query  427  WVLTNRKSDTRKGKVQLIDASEWYVPLRRNLGKKNCELSEEQIQTIVDLVVNPRETE---  483
            W++T+ KS  R+GKVQL+DAS+ Y   R+N+G K  ++SE   + IV+   +  + E   
Sbjct  404  WIITKDKSPERQGKVQLVDASNMYEKRRKNIGEKRVDISEACREMIVQAYGEFNDKEYYL  463

Query  484  -----KSKIFPNEAFGYWKVIVERPLR  505
                  SKI+ NE+FG+ +V +ERP R
Sbjct  464  GDGTVESKILKNESFGFTRVTIERPQR  490


 Score = 64.5 bits (225),  Expect = 3e-11, Method: Compositional matrix adjust.
 Identities = 35/73 (48%), Positives = 49/73 (68%), Gaps = 2/73 (2%)

Query  624  DTALRDSEQVPLLEDGGIEAFFRREVLPYTSDAWIDPGKTLVGYEISFTRHFYRPAPMRT  683
            DT LRD+E++PL ED  I+ +F RE+LP+  DAW+D  K  +GYEI+FTR FY+ +P   
Sbjct  507  DTNLRDTEDIPLTED--INEYFEREILPFNQDAWMDRKKDKIGYEIPFTRLFYKYTPPEP  564

Query  684  LDEIKADIYALEQ  696
             + I   I  LE+
Sbjct  565  SEVISERIKQLEE  577

126) DESAM_20026 in NC_020055


> NC_002953_R1|4|G3|49484939|YP_042160.1|Staphylococcus_aureus_subsp._aureus_MSSA476|-|4742..6529|-|SAS0027|type 
I restriction 
enzyme methylase
Length=595

 Score =  299 bits (1122),  Expect = 3e-82, Method: Compositional matrix adjust.
 Identities = 206/507 (41%), Positives = 331/507 (66%), Gaps = 45/507 (8%)

Query  10   TNFIWNIADDVLRDVYVRGKYRDVILPMTVIRRLDALLEPTKEAVLNMKKQLDSAGIANQ  69
            +N+IWN+AD +LR++Y    Y  VILPMTVI+RL+  L  T++ VL+   + +S     +
Sbjct  18   ANLIWNVAD-ILRGLYKPHEYGKVILPMTVIKRLHDTLLKTRDKVLKTAENTQSINDVMR  76

Query  70   DAALCQASGEAFFNSSPFTLKDLKNRAKVQQLKADFEAYLDGFSPNVQEILDKFKFRNQI  129
            +  L +ASG +F+N+S +T+  L   A   ++ ++F AYL+GFS N+Q+IL++FKF  +I
Sbjct  77   ERLLKNASGYSFYNTSLYTFETLL--ADPANIESNFRAYLNGFSENMQDILNNFKFDVEI  134

Query  130  PTLVEADILGALIEKYLNPSINLSPKPVLDADGTEKLPGLDNHGMGTVFEELIRRFNEEN  189
             T+ + D+L  +I+ + ++   L+P         +K+ + D   MG VFEEL+R+F+E  
Sbjct  135  TTMADNDVLFYVIQEFNKADAYLGP---------DKMTSTD---MGYVFEELVRKFSESY  182

Query  190  NEEAGEHFTPRDVVKLMADLIFLPIADKI-ESGTY-LVYDGACGTGGMLTVAEERLQKLA  247
            NEEAG HFT+RD++ LM+DL+++   D +     +  VYD + GT+ ML+   ER++ + 
Sbjct  183  NEEAGAHFTSRDIIYLMTDLLLIEDKDTLFKEHVFKTVYDQTMGTSQMLSAMTERIHDMN  242

Query  248  KEAGKEVSIHLYGQEVQPETYAIAKADLLLKGEGAEAENIKYGSTLSADAFVSNQFDFML  307
              A     +  +GQE++PETYAI+KAD +++G  +++EN+  GSTL++D F +  FD+ +
Sbjct  243  DTAE----VATFGQELNPETYAISKADTMIRG--GDPENMALGSTLTSDRFEGFTFDYCI  296

Query  308  SNPPYGKSWKTDLERMGGKSDLKD-PRFILEYGDEPEYKMLTRSSDGQLMFLVNKLMKMK  366
            SNPP+G  WK D   + +  +L +  RF +          L R SDGQL+F +N + K+K
Sbjct  297  SNPPFGVDWKKDQKAVKAEHELGELGRFGVG---------LPRVSDGQLLFQLNGISKLK  347

Query  367  ESSKLGSRIAQVHNGSSLFTGDAGQGESNIRRWIIENDWLEAIIALPENIFYNTGISTYI  426
            E++    R+A +HNGS+LF+G++G GES IR+ +IENDWLE+II LP+++FYNTGISTYI
Sbjct  348  ETG----RMAIIHNGSALFSGNPGAGESLIRQYVIENDWLEGIIQLPNDLFYNTGISTYI  403

Query  427  WVLTNRKADTRKGKVQLIYATDWYQSLRKNMGKKNCELNENHIQRICDLIMNPRETE---  483
            W++T+ K+  R+GKVQL+ A++ Y+  RKN+G K  +++E   + I +   +  + E   
Sbjct  404  WIITKDKSPERQGKVQLVDASNMYEKRRKNIGEKRVDISEACREMIVQAYGEFNDKEYYL  463

Query  484  -----QSKIFTNEAFGYQKVIVERPLR  505
                 +SKI+ NE+FG+ +V +ERP R
Sbjct  464  GDGTVESKILKNESFGFTRVTIERPQR  490


 Score = 61.3 bits (213),  Expect = 2e-10, Method: Compositional matrix adjust.
 Identities = 32/57 (57%), Positives = 43/57 (76%), Gaps = 2/57 (3%)

Query  624  DTNLRDSEQVPLLEDGGIAAFIEREVQPYTPDAWIDASKTQIGYEISFTKHFYKPIP  680
            DTNLRD+E++PL ED  I  ++ERE+ P+  DAW+D  K +IGYEI+FT+ FYK  P
Sbjct  507  DTNLRDTEDIPLTED--INEYFEREILPFNQDAWMDRKKDKIGYEIPFTRLFYKYTP  561

127) GM18_2924 in NC_014973


> NC_002953_R1|4|G3|49484939|YP_042160.1|Staphylococcus_aureus_subsp._aureus_MSSA476|-|4742..6529|-|SAS0027|type 
I restriction 
enzyme methylase
Length=595

 Score =  299 bits (1120),  Expect = 4e-82, Method: Compositional matrix adjust.
 Identities = 206/512 (41%), Positives = 326/512 (64%), Gaps = 55/512 (10%)

Query  10   VNFIWGIADDVLRDVYVRGKYRDVILPMTVIRRLDALLEPSKEKVLGMKKQLDGAGIANQ  69
             N+IW +AD +LR++Y    Y  VILPMTVI+RL+  L  +++KVL    + ++     +
Sbjct  18   ANLIWNVAD-ILRGLYKPHEYGKVILPMTVIKRLHDTLLKTRDKVLKTAENTQSINDVMR  76

Query  70   HAALCQAAGEAFYNVSPFTLRDLKNRAKQQQLKADFEAYLDGFSPNVQEILDKFKFRNQI  129
            +  L +A+G +FYN S +T+  L   A   ++ ++F AYL+GFS N+Q+IL++FKF  +I
Sbjct  77   ERLLKNASGYSFYNTSLYTFETLL--ADPANIESNFRAYLNGFSENMQDILNNFKFDVEI  134

Query  130  PTLIEADILGHLIEKFLDGRVNLSPKPVQDVDGNEILPALDNHSMGTIFEELIRRFNEEN  189
             T+ + D+L  +I+ F  +   L+P  +   D            MG +FEEL+R+F+E  
Sbjct  135  TTMADNDVLFYVIQEFNKADAYLGPDKMTSTD------------MGYVFEELVRKFSESY  182

Query  190  NEEAGEHFTPRDVVKLMADLIFLPVADDI-ESGTY-LVYDGACGTGGMLTVAEERLAELA  247
            NEEAG HFT+RD++ LM+DL+++   D +     +  VYD + GT+ ML+   ER+ ++ 
Sbjct  183  NEEAGAHFTSRDIIYLMTDLLLIEDKDTLFKEHVFKTVYDQTMGTSQMLSAMTERIHDMN  242

Query  248  ESHGKDVSIHLFGQEVQPETYAISKADLLLKGEGAEAENMKYGSTLSSDAFPSQEFDFML  307
            ++      +  FGQE++PETYAISKAD +++G  +++ENM  GSTL+SD F +  FD+ +
Sbjct  243  DT----AEVATFGQELNPETYAISKADTMIRG--GDPENMALGSTLTSDRFEGFTFDYCI  296

Query  308  SNPPYGKSWKTDLERLGGKGDIKD-PRFVTQHGGDPEYKMITRSSDGQLMFLVNKLSKMK  366
            SNPP+G  WK D   + +  ++ +  RF            + R SDGQL+F +N +SK+K
Sbjct  297  SNPPFGVDWKKDQKAVKAEHELGELGRFGVG---------LPRVSDGQLLFQLNGISKLK  347

Query  367  HTTRLGSRIAEVHNGSSLFTGDAGQGESNIRRWIIENDWLEAIIALPENMFYNTGIATYI  426
            +T R++     +HNGS+LF+G++G GES IR+ +IENDWLE+II LP+++FYNTGI+TYI
Sbjct  348  ETGRMAI----IHNGSALFSGNPGAGESLIRQYVIENDWLEGIIQLPNDLFYNTGISTYI  403

Query  427  WVLTNRKSDTRRGKVQLIDATEWYVPLRRNLGKKNCEFSEEHIRAIC-DLVVNPV-----  480
            W++T+ KS  R+GKVQL+DA++ Y   R+N+G K  ++SE      C +++V++      
Sbjct  404  WIITKDKSPERQGKVQLVDASNMYEKRRKNIGEKRVDISEA-----CREMIVQAYGEFND  458

Query  481  -------ETDKSKIFPNEAFGYWKVTVDRPLR  505
                    T  SKI+ NE+FG+ +VT++RP R
Sbjct  459  KEYYLGDGTVESKILKNESFGFTRVTIERPQR  490


 Score = 62.9 bits (219),  Expect = 7e-11, Method: Compositional matrix adjust.
 Identities = 34/73 (47%), Positives = 49/73 (68%), Gaps = 2/73 (2%)

Query  624  DTALRDTEQVPLLEEGGIEAFIRREVLPYTPDAWIDPDKTLVGYEISFTRHFYRPAPMRT  683
            DT LRDTE++PL E+  I+ ++ RE+LP+  DAW+D  K  +GYEI+FTR FY+ +P   
Sbjct  507  DTNLRDTEDIPLTED--INEYFEREILPFNQDAWMDRKKDKIGYEIPFTRLFYKYTPPEP  564

Query  684  LDEIKADIYALEQ  696
             + I   I  LE+
Sbjct  565  SEVISERIKQLEE  577

128) Atc_1133 in NC_015850


> NC_002953_R1|4|G3|49484939|YP_042160.1|Staphylococcus_aureus_subsp._aureus_MSSA476|-|4742..6529|-|SAS0027|type 
I restriction 
enzyme methylase
Length=595

 Score =  291 bits (1090),  Expect = 1e-79, Method: Compositional matrix adjust.
 Identities = 206/512 (41%), Positives = 326/512 (64%), Gaps = 36/512 (7%)

Query  1    MTQQNLSALIWAVAELLRGDFKQSEYGRVILPFTVLRRLDCVLAPTRAAALAEYQAKSAA  60
            +  Q+ + LIW VA++LRG +K  EYG+VILP TV++RL+  L  TR   L   +   + 
Sbjct  12   INVQKQANLIWNVADILRGLYKPHEYGKVILPMTVIKRLHDTLLKTRDKVLKTAENTQSI  71

Query  61   KLPFAE-FVRRAAGQPFFNLFPQSLPGLLGDAEHLRDNLSAYVRAFSVDVEDIFLRFDFP  119
            +    E +++ A+G +F+N    ++  LL+D+ ++  N+ AY+ +FS +++DI+  F F 
Sbjct  72   NDVMRERLLKNASGYSFYNTSLYTFETLLADPANIESNFRAYLNGFSENMQDILNNFKFD  131

Query  120  ATIERLHKAGLLYLVTEKFAGLD--LHPDSVSNYQMGllfeellrrfSEMSNETAGEHYT  177
              I  +   ++L+ V + F   D  L PD +++ +MG +FEEL+R+FSE  NE AG H+T
Sbjct  132  VEITTMADNDVLFYVIQEFNKADAYLGPDKMTSTDMGYVFEELVRKFSESYNEEAGAHFT  191

Query  178  PREVIQLMVELLFCEDDAALAQASVVRTLYDPTAGTGGMLSVAAEYLHGINPNARLTLFG  237
            +R++I LM +LL+ ED  +L +  V +T+YD T GT+ MLS  +E +H++N  A ++ FG
Sbjct  192  SRDIIYLMTDLLLIEDKDTLFKEHVFKTVYDQTMGTSQMLSAMTERIHDMNDTAEVATFG  251

Query  238  QELNDESYATCKADMLLRGQDVGNILPGNTLSDDGHRAMRFDYMLSNPPFGVEWKKVEDE  297
            QELN E+YA  KAD ++RG D  N+  G+TL+ D   +  FDY +SNPPFGV+WKK +  
Sbjct  252  QELNPETYAISKADTMIRGGDPENMALGSTLTSDRFEGFTFDYCISNPPFGVDWKKDQKA  311

Query  298  VRAEHEERGYRGRFGPGLPRISDGSllfllhllSKMRPVKDGGSRIGIVLNGSPLFTGSA  357
            V+AEH E G  GRFG GLPR+SDG LLF L+ +SK++      +R++I+ NGS+LF+G++
Sbjct  312  VKAEH-ELGELGRFGVGLPRVSDGQLLFQLNGISKLK----ETGRMAIIHNGSALFSGNP  366

Query  358  GSGESEIRRYVLEKDYVEAIVALPTDMFFNTGIATYVWILSNRKAPERAGMVQLIDGSGF  417
            G+GES IR+YV+E+D +E+I+ LP D+F+NTGI+TY+WI+++ K+PER G VQL+D+S  
Sbjct  367  GAGESLIRQYVIENDWLEGIIQLPNDLFYNTGISTYIWIITKDKSPERQGKVQLVDASNM  426

Query  418  WRKMRKSLGSKRRELAPEHIRTITRILGSYQELQQAVVLDAEGKELERRVLFAGEPMPEA  477
              K RK++G KR +++      I +  G +++                +  + G+   E 
Sbjct  427  YEKRRKNIGEKRVDISEACREMIVQAYGEFND----------------KEYYLGDGTVE-  469

Query  478  PEGGKIQLLPVSRIFRTTDFGYRTITVERPLR  509
                       S+I++   FG+  +T+ERP R
Sbjct  470  -----------SKILKNESFGFTRVTIERPQR  490


 Score = 75.5 bits (267),  Expect = 1e-14, Method: Compositional matrix adjust.
 Identities = 42/99 (43%), Positives = 61/99 (62%), Gaps = 9/99 (9%)

Query  619  KRQGPKYEPDTALRDTENVPLGEDVYAYFAREVLPHVPDAWIDETKRDTQDGKVGIVGYE  678
            K++G+K   DT LRDTE++PL ED+  YF RE+LP   DAW+D  K        + +GYE
Sbjct  499  KKNGSK-SVDTNLRDTEDIPLTEDINEYFEREILPFNQDAWMDRKK--------DKIGYE  549

Query  679  IPFNRHFYVYEPPRPLAEIRADLQAVTARILEKLQGMAG  717
            IPF R FY Y PP P   I   ++ +   I+ ++Q+++G
Sbjct  550  IPFTRLFYKYTPPEPSEVISERIKQLEESIIKNFQALSG  588

129) NIDE1898 in NC_014355


> NC_002953_R1|4|G3|49484939|YP_042160.1|Staphylococcus_aureus_subsp._aureus_MSSA476|-|4742..6529|-|SAS0027|type 
I restriction 
enzyme methylase
Length=595

 Score =  291 bits (1090),  Expect = 1e-79, Method: Compositional matrix adjust.
 Identities = 205/510 (41%), Positives = 334/510 (66%), Gaps = 48/510 (9%)

Query  10   ANFIWGIADDVLRDLYVRGKYRDVILPMTVLRRLDAVLEPTKQAVLDMKVSLDKAKIVHQ  69
            AN+IW +AD +LR+LY    Y  VILPMTV++RL+  L  T++ VL    + +  + V +
Sbjct  18   ANLIWNVAD-ILRGLYKPHEYGKVILPMTVIKRLHDTLLKTRDKVLKTAENTQSINDVMR  76

Query  70   DQALRQAAGQAFYNTSKFTLKDLKARSSQQQLRADFEAYLDGFSPNVQDILEKFEFRNQI  129
            ++ L++A+G +FYNTS +T+  L A +++  + ++F AYL+GFS N+QDIL++F F  +I
Sbjct  77   ERLLKNASGYSFYNTSLYTFETLLADPAN--IESNFRAYLNGFSENMQDILNNFKFDVEI  134

Query  130  PRLSKADALGTLINKFLSPDINLSPNPVKNNDGSMKHPGLDNHAMGTVFEELVRRFNEEN  189
              ++  D L  +I+ F  +D  L+P+ + + D            MG VFEELVR+F+E  
Sbjct  135  TTMADNDVLFYVIQEFNKADAYLGPDKMTSTD------------MGYVFEELVRKFSESY  182

Query  190  NEEAGEHWTPRDAVKLMARLIFLPIADQI-QSGTY-LLYDGACGTGGMLTVAEETLQQLA  247
            NEEAG H T+RD + LM+ L+++   D + +   +  +YD + GT+ ML+   E ++++ 
Sbjct  183  NEEAGAHFTSRDIIYLMTDLLLIEDKDTLFKEHVFKTVYDQTMGTSQMLSAMTERIHDM-  241

Query  248  AEHRKKVATHLYGQEINAETYAIAKADLLLKGEGDAADNIVGGPEYSTLANDAFRSREFD  307
             ++   VAT  +GQE+N+ETYAI+KAD +++G GD+ +  +G    STL++D F +  FD
Sbjct  242  -NDTAEVAT--FGQELNPETYAISKADTMIRG-GDPENMALG----STLTSDRFEGFTFD  293

Query  308  FMLSNPPYGKSWKSDLERLGGKEGIKD-PRFMIQHAGEAEYSLITRSSDGQMLFLANMLS  366
            + +SNPP+G  WK D   + + + + +  RF +          + R SDGQ+LF  N +S
Sbjct  294  YCISNPPFGVDWKKDQKAVKAEHELGELGRFGVG---------LPRVSDGQLLFQLNGIS  344

Query  367  KMKHKTKLGSRIAEVHNGSSLFTGDAGQGESNIRRWIIENDWLEAIVALPLNMFYNTGIA  426
            K+K+     +R+A +HNGS+LF+G++G GES IR+ +IENDWLE+I+ LP ++FYNTGI+
Sbjct  345  KLKE----TGRMAIIHNGSALFSGNPGAGESLIRQYVIENDWLEGIIQLPNDLFYNTGIS  400

Query  427  TYIWVLTNRKPAHRQGKVQLIDATQWFKPLRKNLGKKNCELSDEDIRRICDTFIDFKESE  486
            TYIW++T+ K+++RQGKVQL+DA++ +   RKN+G K  ++S+     I +++ +F++ E
Sbjct  401  TYIWIITKDKSPERQGKVQLVDASNMYEKRRKNIGEKRVDISEACREMIVQAYGEFNDKE  460

Query  487  --------QSKIFPNEAFGYWKVTVERPLR  508
                    +SKI+ NE+FG+ +VT+ERP R
Sbjct  461  YYLGDGTVESKILKNESFGFTRVTIERPQR  490


 Score = 53.2 bits (182),  Expect = 6e-08, Method: Compositional matrix adjust.
 Identities = 34/68 (50%), Positives = 42/68 (62%), Gaps = 2/68 (2%)

Query  627  DTELRDTEQIPLLEEGGIAAFIRREVLPHVPDAWYVPESVKTGYEISFTRYFYKPQPLRS  686
            DT+LRDTE+IPL E+  I  ++ RE+LP   DAW      K GYEI+FTR FYK  P  +
Sbjct  507  DTNLRDTEDIPLTED--INEYFEREILPFNQDAWMDRKKDKIGYEIPFTRLFYKYTPPEP  564

Query  687  LEAIRADI  694
             E I   I
Sbjct  565  SEVISERI  572

130) Smon_0657 in NC_013515


> NC_002953_R1|4|G3|49484939|YP_042160.1|Staphylococcus_aureus_subsp._aureus_MSSA476|-|4742..6529|-|SAS0027|type 
I restriction 
enzyme methylase
Length=595

 Score =  287 bits (1075),  Expect = 2e-78, Method: Compositional matrix adjust.
 Identities = 211/522 (41%), Positives = 330/522 (64%), Gaps = 51/522 (9%)

Query  6    NALEYNKLISFIWSVADDCLRDVYVRGKYRDVILPMTVIRRFDSIIEPEKANIMKVKEMA  65
             +++ +K  ++IW+VAD  LR++Y    Y  VILPMTVI+R++  +   + +++K  E +
Sbjct  10   TSINVQKQANLIWNVAD-ILRGLYKPHEYGKVILPMTVIKRLHDTLLKTRDKVLKTAENT  68

Query  66   EKQGWDVTKT--LDTAVGLPFYNTSNFCLKDLKHETNRQNLKKNFEEYLNGFSENVKEIL  123
            +    DV +   L  A G +FYNTS + +  L  +    N+  NF  YLNGFSEN+++IL
Sbjct  69   QSIN-DVMRERLLKNASGYSFYNTSLYTFETLLADPA--NIESNFRAYLNGFSENMQDIL  125

Query  124  QKFDFNNQVTKMTDAGILGSVIEKFTSSELNLSPYDEKNSSGDIIKKGLDNHAMGTLFEE  183
            ++F F+ ++T M+D ++L  VI+ F  ++  L+P  +K +S D          MG +FEE
Sbjct  126  NNFKFDVEITTMADNDVLFYVIQEFNKADAYLGP--DKMTSTD----------MGYVFEE  173

Query  184  IIRKFNEENNEEAGEHFTPRDLIELMADITMYPIMDKI-KNGTY-SIYDGACGTLGMGTV  241
            ++RKF+E  NEEAG HFT+RD+I LM+D+ +    D + K+  + ++YD + GT  M + 
Sbjct  174  LVRKFSESYNEEAGAHFTSRDIIYLMTDLLLIEDKDTLFKEHVFKTVYDQTMGTSQMLSA  233

Query  242  AEERLKAFAKENDKEVSIHLIGQEVNPETYAISKADLLIKGGDTDSNNVYYGSTLSDDRT  301
              ER+     + +    +  +GQE+NPETYAISKAD +I+GGD ++  +  GSTL+ DR 
Sbjct  234  MTERIH----DMNDTAEVATFGQELNPETYAISKADTMIRGGDPENMAL--GSTLTSDRF  287

Query  302  SGQHFDFMLSNPPYGKTWKTDLAILGSGNDKDPKKNIIDRRFVRNYKEQDDFRMIPDVSD  361
             G  FD+ +SNPP+G  WK D   + + ++ +        RF            +P VSD
Sbjct  288  EGFTFDYCISNPPFGVDWKKDQKAVKAEHELGELG-----RFGVG---------LPRVSD  333

Query  362  GQLLFLLNNISKMKETEMGSRIVEVHNGSALFTGDAGNGASNARRFMIEEDLIEAIIQLP  421
            GQLLF LN ISK+KET   +R+  +HNGSALF+G++G G S  R+++IE+D +E+IIQLP
Sbjct  334  GQLLFQLNGISKLKET---GRMAIIHNGSALFSGNPGAGESLIRQYVIENDWLEGIIQLP  390

Query  422  ENMFYNTGITTYIWILSNRKEERRKGKIQLINANGIKTALRKNMGKKNCEFSEADREFIL  481
            +++FYNTGI+TYIWI+++ K   R+GK+QL++A+ +    RKN+G K  ++SEA RE I+
Sbjct  391  NDLFYNTGISTYIWIITKDKSPERQGKVQLVDASNMYEKRRKNIGEKRVDISEACREMIV  450

Query  482  NQYLKFEENEY--------SKIFLNDEFGYYKVVVERPLRQA  515
            + Y  F+++EY        SKI+ N+ FG+ +V +ERP R+ 
Sbjct  451  QAYGEFNDKEYYLGDGTVESKILKNESFGFTRVTIERPQRDE  492


 Score = 67.9 bits (238),  Expect = 2e-12, Method: Compositional matrix adjust.
 Identities = 42/89 (48%), Positives = 61/89 (69%), Gaps = 2/89 (2%)

Query  621  RDESAVIQKDSKGNVIVDPDLRDTESIPMTFEGGIEEFIKKEVLPYHADAFVDESKTQIG  680
            RDE++ I    +G+  VD +LRDTE IP+T   +I+E++ +E+LP++ DA +D  K +IG
Sbjct  490  RDENGDIVYKKNGSKSVDTNLRDTEDIPLT--EDINEYFEREILPFNQDAWMDRKKDKIG  547

Query  681  YEINFTKYFYKAKELESVEDIVSRIKELE  709
            YEI FT+ FYK    E+ E I  RIK+LE
Sbjct  548  YEIPFTRLFYKYTPPEPSEVISERIKQLE  576

131) Cphamn1_0751 in NC_010831


> NC_002953_R1|4|G3|49484939|YP_042160.1|Staphylococcus_aureus_subsp._aureus_MSSA476|-|4742..6529|-|SAS0027|type 
I restriction 
enzyme methylase
Length=595

 Score =  284 bits (1064),  Expect = 1e-77, Method: Compositional matrix adjust.
 Identities = 197/483 (41%), Positives = 319/483 (67%), Gaps = 18/483 (3%)

Query  11   VSFLWAIADLLNGAFKKSEFQKIILPFTVLRRLDYALEKTKAKVLETEHTLKAKGLENRH  70
             +++W +AD+L G +K  E+ K+ILP TV++RL+ +L KT+ KVL T +  ++     R+
Sbjct  18   ANLIWNVADILRGLYKPHEYGKVILPMTVIKRLHDTLLKTRDKVLKTAENTQSINDVMRE  77

Query  71   GQLCRAAGYAFYNTSKFNYESLLHDDTNLALNLRQYVMGFSPNVREIFAAFNFDDTIRDL  130
              L  A+GY+FYNTS + +E+LL D +N+  N+R Y+ GFS N+++I+  F+FD  I  +
Sbjct  78   RLLKNASGYSFYNTSLYTFETLLADPANIESNFRAYLNGFSENMQDILNNFKFDVEITTM  137

Query  131  GRVNLLYLLMERFNEKSKVDLRPASMSNHEMGYVFEHLLRKFNEALNENPGEHFTPRDAI  190
            +  ++L+ +++ FN K+   L P  M++ +MGYVFE+L+RKF+E+ NE++G HFT+RD I
Sbjct  138  ADNDVLFYVIQEFN-KADAYLGPDKMTSTDMGYVFEELVRKFSESYNEEAGAHFTSRDII  196

Query  191  RLMVDLVLMLDSELAGTEGIPRTVYDCGCGTGGILSITKEHVLQINPQAKVFLYGQELNP  250
             LM DL+L+ D +    E + +TVYD   GT+ +LS   E++ ++N  A V  +GQELNP
Sbjct  197  YLMTDLLLIEDKDTLFKEHVFKTVYDQTMGTSQMLSAMTERIHDMNDTAEVATFGQELNP  256

Query  251  FTWAIARADMLILEPEGKDAENIKCGSTLSDDQLSDMRFDLQFVNPPYGYEWSKDYDAVT  310
             T AI++AD +I    G D+EN+  GSTL+ D++ +  FD  + NPP+G +W KD  AV 
Sbjct  257  ETYAISKADTMI---RGGDPENMALGSTLTSDRFEGFTFDYCISNPPFGVDWKKDQKAVK  313

Query  311  aeaargfdgrfgagTPRKSDGQMLFLQHLIARMNDPEESQSYIGIILNGSPLFTGGAASG  370
            AE   G  GRFG G PR SDGQ+LF  + I+++++       ++II NGS+LF+G +++G
Sbjct  314  AEHELGELGRFGVGLPRVSDGQLLFQLNGISKLKETGR----MAIIHNGSALFSGNPGAG  369

Query  371  ESEIRRWIMENDWLEAIVAMPQQLFYNTGIGTYIWLLSNRKPAKHKGKVMLVDASGEEFW  430
            ES IR+ ++ENDWLE+I+ +P++LFYNTGI+TYIW++++ K++ ++GKV LVDAS  +  
Sbjct  370  ESLIRQYVIENDWLEGIIQLPNDLFYNTGISTYIWIITKDKSPERQGKVQLVDAS--NMY  427

Query  431  SGMSKSLGSKRREITEDHKQAILNLVK--------VRKEGPHVKLFDTTDFGYREIKVLR  482
                K++G KR +I+E  ++ I++           +     + K++    FG+  + + R
Sbjct  428  EKRRKNIGEKRVDISEACREMIVQAYGEFNDKEYYLGDGTVESKILKNESFGFTRVTIER  487

Query  483  PLK  485
            P +
Sbjct  488  PQR  490


 Score = 71.5 bits (252),  Expect = 2e-13, Method: Compositional matrix adjust.
 Identities = 37/107 (35%), Positives = 63/107 (59%), Gaps = 8/107 (7%)

Query  579  ERDDAAEVCRDKDGNPEPDTDLNDTENVPLKEKVETYFAREVTPHVPDAWIDPAYCDAKD  638
            +RD+ +++   K+G+   DT+L DTE++PL E ++ YF RE+ P   DAW+D        
Sbjct  489  QRDENGDIVYKKNGSKSVDTNLRDTEDIPLTEDINEYFEREILPFNQDAWMDR-------  541

Query  639  GQVGRVGYEIPFNRHFYVFQPPRLLSAIDADLKTSTDRILNMIGGLT  685
             + +++GYEIPF R FY + PP     I   +K   + I++ + +L+
Sbjct  542  -KKDKIGYEIPFTRLFYKYTPPEPSEVISERIKQLEESIIKNFQALS  587