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Homologs of msr(E) gene of NC_016808_R1

protein-level

Hit (GenBank Accn)

Product

Source Genome

Eval.

Ident.(%)

1) BJAB07104_p0097
( YP_008211320.1 )

ATPase component of ABC transporters with duplicated ATPase domains

NC_021728
(Acinetobacter baumannii BJAB07104)

0.0

100

2) BJAB0868_p0108
( YP_008215140.1 )

ATPase component of ABC transporters with duplicated ATPase domains

NC_021732
(Acinetobacter baumannii BJAB0868)

0.0

100

3) ABTJ_01335
( YP_006289241.1 )

ABC transporter ATPase

NC_017847
(Acinetobacter baumannii MDR-TJ)

0.0

100

4) ABZJ_p00013
( YP_005527832.1 )

macrolide efflux protein

NC_017172
(Acinetobacter baumannii MDR-ZJ06)

0.0

100

5) M3Q_2654
( YP_006848973.1 )

hypothetical protein

NC_018706
(Acinetobacter baumannii TYTH-1)

0.0

100

6) WQG_1100
( YP_007547187.1 )

Macrolide efflux protein

NC_020515
(Bibersteinia trehalosi USDA-ARS-USMARC-192)

0.0

100

7) A225_R1p0735
( YP_006501607.1 )

macrolide efflux protein

NC_018107
(Klebsiella oxytoca E718)

0.0

100

8) A225_R1p0475
( YP_006501710.1 )

macrolide efflux protein

NC_018107
(Klebsiella oxytoca E718)

0.0

100

9) msr(E)
( YP_005176244.1 )

macrolide efflux protein

NC_016808
(Pasteurella multocida 36950)

0.0

100

10) GYMC10_3536
( YP_003243580.1 )

ABC transporter-like protein

NC_013406
(Paenibacillus sp. Y412MC10)

6e-153

11) Desmer_1358
( YP_006621234.1 )

ABC transporter ATPase

NC_018515
(Desulfosporosinus meridiei DSM 13257)

4e-151

12) Desru_2756
( YP_004546262.1 )

ABC transporter-like protein

NC_015589
(Desulfotomaculum ruminis DSM 2154)

3e-150

13) HMPREF0424_0873
( YP_003374090.1 )

ABC transporter ATP-binding protein

NC_013721
(Gardnerella vaginalis 409-05)

9e-148

14) MYY_1872
( YP_006254062.1 )

Mel protein

NC_017769
(Streptococcus pneumoniae ST556)

9e-148

15) SPT_1925
( YP_002743273.1 )

Mel protein

NC_012469
(Streptococcus pneumoniae Taiwan19F-14)

9e-148

16) HMPREF0837_12213
( YP_003725655.1 )

ABC transporter ATP-binding protein

NC_014251
(Streptococcus pneumoniae TCH8431/19A)

9e-148

17) Dtox_2791
( YP_003192182.1 )

ABC transporter

NC_013216
(Desulfotomaculum acetoxidans DSM 771)

2e-146

18) Amet_1903
( YP_001319726.1 )

ABC transporter-like protein

NC_009633
(Alkaliphilus metalliredigens QYMF)

5e-146

19) SPPN_01640
( YP_004767632.1 )

ABC transporter ATP-binding protein

NC_015875
(Streptococcus pseudopneumoniae IS7493)

1e-143

20) SSUJS14_0633
( YP_006075995.1 )

Mel protein

NC_017618
(Streptococcus suis JS14)

4e-143

21) NJAUSS_0619
( YP_007570574.1 )

Erythromycin resistance ATP-binding protein MsrA

NC_020526
(Streptococcus suis SC070731)

4e-143

22) SDSE_1551
( YP_006905103.1 )

Ribose import ATP-binding protein rbsA

NC_019042
(Streptococcus dysgalactiae AC-2713)

2e-141

23) Dhaf_0018
( YP_002456523.1 )

ABC transporter

NC_011830
(Desulfitobacterium hafniense DCB-2)

5e-140

24) CKL_2618
( YP_001396001.1 )

ABC transporter ATPase

NC_009706
(Clostridium kluyveri DSM 555)

2e-139

25) CKR_2319
( YP_002472784.1 )

hypothetical protein

NC_011837
(Clostridium kluyveri NBRC 12016)

2e-139

26) CKL_2537
( YP_001395920.1 )

transporter

NC_009706
(Clostridium kluyveri DSM 555)

2e-138

27) CKR_2248
( YP_002472713.1 )

hypothetical protein

NC_011837
(Clostridium kluyveri NBRC 12016)

2e-138

28) SPNINV200_08750
( YP_006066186.1 )

Macrolide efflux transporter

NC_017593
(Streptococcus pneumoniae INV200)

4e-137

29) M6_Spy1165
( YP_060483.1 )

macrolide ABC transporter ATPase

NC_006086
(Streptococcus pyogenes MGAS10394)

4e-137

30) Clo1100_1986
( YP_005147983.1 )

ABC transporter ATPase

NC_016791
(Clostridium sp. BNL1100)

1e-135

31) Closa_1123
( YP_003821361.1 )

ABC transporter

NC_014376
(Clostridium saccharolyticum WM1)

4e-130

32) DSY0081
( YP_516314.1 )

hypothetical protein

NC_007907
(Desulfitobacterium hafniense Y51)

7e-116

33) msrA
( YP_001700102.1 )

erythromycin resistance ATP-binding protein

NC_010382
(Lysinibacillus sphaericus C3-41)

9e-100

34) B1NLA3E_11850
( YP_007910619.1 )

erythromycin resistance ATP-binding protein

NC_021171
(Bacillus sp. 1NLA3E)

1e-94

35) OB0699
( NP_691620.1 )

erythromycin resistance protein

NC_004193
(Oceanobacillus iheyensis HTE831)

3e-82

36) SSIL_2504
( YP_006463073.1 )

ABC transporter ATP-binding protein

NC_018065
(Solibacillus silvestris StLB046)

9e-80

37) MC28_4411
( YP_006831232.1 )

Low molecular weight phosphotyrosine protein phosphatase

NC_018693
(Bacillus thuringiensis MC28)

1e-68

• Sequence Alignments

1) BJAB07104_p0097 in NC_021728


> NC_016808_R1|79|G72|378774001|YP_005176244.1|Pasteurella_multocida_36950|+|67348..68823|msr(E)|Pmu_03460|macrolide 
efflux 
protein
Length=491

 Score =  793 bits (3001),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 491/491 (100%), Positives = 491/491 (100%), Gaps = 0/491 (0%)

Query  1    MSLIIKARNIRLDYAGRDVLDIDELEIHSYDRIGLVGDNGAGKSSLLKVLNGEIVLAEAT  60
            MSLIIKARNIRLDYAGRDVLDIDELEIHSYDRIGLVGDNGAGKSSLLKVLNGEIVLAEAT
Sbjct  1    MSLIIKARNIRLDYAGRDVLDIDELEIHSYDRIGLVGDNGAGKSSLLKVLNGEIVLAEAT  60

Query  61   LQRFGDFAHISQLGGIEIETVEDRAMLSRLGVSNVQNDTMSGGEETRAKIAAAFSQQVHG  120
            LQRFGDFAHISQLGGIEIETVEDRAMLSRLGVSNVQNDTMSGGEETRAKIAAAFSQQVHG
Sbjct  61   LQRFGDFAHISQLGGIEIETVEDRAMLSRLGVSNVQNDTMSGGEETRAKIAAAFSQQVHG  120

Query  121  ILADEPTSHLDLNGIDLLIGQLKAFDGALLVISHDRYFLDMVVDKIWELKDGKITEYWGG  180
            ILADEPTSHLDLNGIDLLIGQLKAFDGALLVISHDRYFLDMVVDKIWELKDGKITEYWGG
Sbjct  121  ILADEPTSHLDLNGIDLLIGQLKAFDGALLVISHDRYFLDMVVDKIWELKDGKITEYWGG  180

Query  181  YSDYLRQKEEERQHQAVEYELMMKERERLESAVQEKRQQANRLDNKKKGEKSKNSTESAG  240
            YSDYLRQKEEERQHQAVEYELMMKERERLESAVQEKRQQANRLDNKKKGEKSKNSTESAG
Sbjct  181  YSDYLRQKEEERQHQAVEYELMMKERERLESAVQEKRQQANRLDNKKKGEKSKNSTESAG  240

Query  241  RLGHAKMTGTKQRKLYQAAKSMEKRLAALEDIQAPEHLRSIRFRQSSALELHNKFPITAD  300
            RLGHAKMTGTKQRKLYQAAKSMEKRLAALEDIQAPEHLRSIRFRQSSALELHNKFPITAD
Sbjct  241  RLGHAKMTGTKQRKLYQAAKSMEKRLAALEDIQAPEHLRSIRFRQSSALELHNKFPITAD  300

Query  301  GLSLKFGSRTIFDDANFIIPLGAKVAITGSNGTGKTSLLKMISERADGLTISPKAEIGYF  360
            GLSLKFGSRTIFDDANFIIPLGAKVAITGSNGTGKTSLLKMISERADGLTISPKAEIGYF
Sbjct  301  GLSLKFGSRTIFDDANFIIPLGAKVAITGSNGTGKTSLLKMISERADGLTISPKAEIGYF  360

Query  361  TQTGYKFNTHKSVLSFMQEECEYTVAEIRAVLASMGIGANDIQKNLSDLSGGEIIKLLLS  420
            TQTGYKFNTHKSVLSFMQEECEYTVAEIRAVLASMGIGANDIQKNLSDLSGGEIIKLLLS
Sbjct  361  TQTGYKFNTHKSVLSFMQEECEYTVAEIRAVLASMGIGANDIQKNLSDLSGGEIIKLLLS  420

Query  421  KMLLGKYNILLMDEPGNYLDLKSIAALETMMKSYAGTIIFVSHDKQLVDNIADIIYEIKD  480
            KMLLGKYNILLMDEPGNYLDLKSIAALETMMKSYAGTIIFVSHDKQLVDNIADIIYEIKD
Sbjct  421  KMLLGKYNILLMDEPGNYLDLKSIAALETMMKSYAGTIIFVSHDKQLVDNIADIIYEIKD  480

Query  481  HKIIKTFERDC  491
            HKIIKTFERDC
Sbjct  481  HKIIKTFERDC  491

2) BJAB0868_p0108 in NC_021732


> NC_016808_R1|79|G72|378774001|YP_005176244.1|Pasteurella_multocida_36950|+|67348..68823|msr(E)|Pmu_03460|macrolide 
efflux 
protein
Length=491

 Score =  793 bits (3001),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 491/491 (100%), Positives = 491/491 (100%), Gaps = 0/491 (0%)

Query  1    MSLIIKARNIRLDYAGRDVLDIDELEIHSYDRIGLVGDNGAGKSSLLKVLNGEIVLAEAT  60
            MSLIIKARNIRLDYAGRDVLDIDELEIHSYDRIGLVGDNGAGKSSLLKVLNGEIVLAEAT
Sbjct  1    MSLIIKARNIRLDYAGRDVLDIDELEIHSYDRIGLVGDNGAGKSSLLKVLNGEIVLAEAT  60

Query  61   LQRFGDFAHISQLGGIEIETVEDRAMLSRLGVSNVQNDTMSGGEETRAKIAAAFSQQVHG  120
            LQRFGDFAHISQLGGIEIETVEDRAMLSRLGVSNVQNDTMSGGEETRAKIAAAFSQQVHG
Sbjct  61   LQRFGDFAHISQLGGIEIETVEDRAMLSRLGVSNVQNDTMSGGEETRAKIAAAFSQQVHG  120

Query  121  ILADEPTSHLDLNGIDLLIGQLKAFDGALLVISHDRYFLDMVVDKIWELKDGKITEYWGG  180
            ILADEPTSHLDLNGIDLLIGQLKAFDGALLVISHDRYFLDMVVDKIWELKDGKITEYWGG
Sbjct  121  ILADEPTSHLDLNGIDLLIGQLKAFDGALLVISHDRYFLDMVVDKIWELKDGKITEYWGG  180

Query  181  YSDYLRQKEEERQHQAVEYELMMKERERLESAVQEKRQQANRLDNKKKGEKSKNSTESAG  240
            YSDYLRQKEEERQHQAVEYELMMKERERLESAVQEKRQQANRLDNKKKGEKSKNSTESAG
Sbjct  181  YSDYLRQKEEERQHQAVEYELMMKERERLESAVQEKRQQANRLDNKKKGEKSKNSTESAG  240

Query  241  RLGHAKMTGTKQRKLYQAAKSMEKRLAALEDIQAPEHLRSIRFRQSSALELHNKFPITAD  300
            RLGHAKMTGTKQRKLYQAAKSMEKRLAALEDIQAPEHLRSIRFRQSSALELHNKFPITAD
Sbjct  241  RLGHAKMTGTKQRKLYQAAKSMEKRLAALEDIQAPEHLRSIRFRQSSALELHNKFPITAD  300

Query  301  GLSLKFGSRTIFDDANFIIPLGAKVAITGSNGTGKTSLLKMISERADGLTISPKAEIGYF  360
            GLSLKFGSRTIFDDANFIIPLGAKVAITGSNGTGKTSLLKMISERADGLTISPKAEIGYF
Sbjct  301  GLSLKFGSRTIFDDANFIIPLGAKVAITGSNGTGKTSLLKMISERADGLTISPKAEIGYF  360

Query  361  TQTGYKFNTHKSVLSFMQEECEYTVAEIRAVLASMGIGANDIQKNLSDLSGGEIIKLLLS  420
            TQTGYKFNTHKSVLSFMQEECEYTVAEIRAVLASMGIGANDIQKNLSDLSGGEIIKLLLS
Sbjct  361  TQTGYKFNTHKSVLSFMQEECEYTVAEIRAVLASMGIGANDIQKNLSDLSGGEIIKLLLS  420

Query  421  KMLLGKYNILLMDEPGNYLDLKSIAALETMMKSYAGTIIFVSHDKQLVDNIADIIYEIKD  480
            KMLLGKYNILLMDEPGNYLDLKSIAALETMMKSYAGTIIFVSHDKQLVDNIADIIYEIKD
Sbjct  421  KMLLGKYNILLMDEPGNYLDLKSIAALETMMKSYAGTIIFVSHDKQLVDNIADIIYEIKD  480

Query  481  HKIIKTFERDC  491
            HKIIKTFERDC
Sbjct  481  HKIIKTFERDC  491

3) ABTJ_01335 in NC_017847


> NC_016808_R1|79|G72|378774001|YP_005176244.1|Pasteurella_multocida_36950|+|67348..68823|msr(E)|Pmu_03460|macrolide 
efflux 
protein
Length=491

 Score =  793 bits (3001),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 491/491 (100%), Positives = 491/491 (100%), Gaps = 0/491 (0%)

Query  1    MSLIIKARNIRLDYAGRDVLDIDELEIHSYDRIGLVGDNGAGKSSLLKVLNGEIVLAEAT  60
            MSLIIKARNIRLDYAGRDVLDIDELEIHSYDRIGLVGDNGAGKSSLLKVLNGEIVLAEAT
Sbjct  1    MSLIIKARNIRLDYAGRDVLDIDELEIHSYDRIGLVGDNGAGKSSLLKVLNGEIVLAEAT  60

Query  61   LQRFGDFAHISQLGGIEIETVEDRAMLSRLGVSNVQNDTMSGGEETRAKIAAAFSQQVHG  120
            LQRFGDFAHISQLGGIEIETVEDRAMLSRLGVSNVQNDTMSGGEETRAKIAAAFSQQVHG
Sbjct  61   LQRFGDFAHISQLGGIEIETVEDRAMLSRLGVSNVQNDTMSGGEETRAKIAAAFSQQVHG  120

Query  121  ILADEPTSHLDLNGIDLLIGQLKAFDGALLVISHDRYFLDMVVDKIWELKDGKITEYWGG  180
            ILADEPTSHLDLNGIDLLIGQLKAFDGALLVISHDRYFLDMVVDKIWELKDGKITEYWGG
Sbjct  121  ILADEPTSHLDLNGIDLLIGQLKAFDGALLVISHDRYFLDMVVDKIWELKDGKITEYWGG  180

Query  181  YSDYLRQKEEERQHQAVEYELMMKERERLESAVQEKRQQANRLDNKKKGEKSKNSTESAG  240
            YSDYLRQKEEERQHQAVEYELMMKERERLESAVQEKRQQANRLDNKKKGEKSKNSTESAG
Sbjct  181  YSDYLRQKEEERQHQAVEYELMMKERERLESAVQEKRQQANRLDNKKKGEKSKNSTESAG  240

Query  241  RLGHAKMTGTKQRKLYQAAKSMEKRLAALEDIQAPEHLRSIRFRQSSALELHNKFPITAD  300
            RLGHAKMTGTKQRKLYQAAKSMEKRLAALEDIQAPEHLRSIRFRQSSALELHNKFPITAD
Sbjct  241  RLGHAKMTGTKQRKLYQAAKSMEKRLAALEDIQAPEHLRSIRFRQSSALELHNKFPITAD  300

Query  301  GLSLKFGSRTIFDDANFIIPLGAKVAITGSNGTGKTSLLKMISERADGLTISPKAEIGYF  360
            GLSLKFGSRTIFDDANFIIPLGAKVAITGSNGTGKTSLLKMISERADGLTISPKAEIGYF
Sbjct  301  GLSLKFGSRTIFDDANFIIPLGAKVAITGSNGTGKTSLLKMISERADGLTISPKAEIGYF  360

Query  361  TQTGYKFNTHKSVLSFMQEECEYTVAEIRAVLASMGIGANDIQKNLSDLSGGEIIKLLLS  420
            TQTGYKFNTHKSVLSFMQEECEYTVAEIRAVLASMGIGANDIQKNLSDLSGGEIIKLLLS
Sbjct  361  TQTGYKFNTHKSVLSFMQEECEYTVAEIRAVLASMGIGANDIQKNLSDLSGGEIIKLLLS  420

Query  421  KMLLGKYNILLMDEPGNYLDLKSIAALETMMKSYAGTIIFVSHDKQLVDNIADIIYEIKD  480
            KMLLGKYNILLMDEPGNYLDLKSIAALETMMKSYAGTIIFVSHDKQLVDNIADIIYEIKD
Sbjct  421  KMLLGKYNILLMDEPGNYLDLKSIAALETMMKSYAGTIIFVSHDKQLVDNIADIIYEIKD  480

Query  481  HKIIKTFERDC  491
            HKIIKTFERDC
Sbjct  481  HKIIKTFERDC  491

4) ABZJ_p00013 in NC_017172


> NC_016808_R1|79|G72|378774001|YP_005176244.1|Pasteurella_multocida_36950|+|67348..68823|msr(E)|Pmu_03460|macrolide 
efflux 
protein
Length=491

 Score =  793 bits (3001),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 491/491 (100%), Positives = 491/491 (100%), Gaps = 0/491 (0%)

Query  1    MSLIIKARNIRLDYAGRDVLDIDELEIHSYDRIGLVGDNGAGKSSLLKVLNGEIVLAEAT  60
            MSLIIKARNIRLDYAGRDVLDIDELEIHSYDRIGLVGDNGAGKSSLLKVLNGEIVLAEAT
Sbjct  1    MSLIIKARNIRLDYAGRDVLDIDELEIHSYDRIGLVGDNGAGKSSLLKVLNGEIVLAEAT  60

Query  61   LQRFGDFAHISQLGGIEIETVEDRAMLSRLGVSNVQNDTMSGGEETRAKIAAAFSQQVHG  120
            LQRFGDFAHISQLGGIEIETVEDRAMLSRLGVSNVQNDTMSGGEETRAKIAAAFSQQVHG
Sbjct  61   LQRFGDFAHISQLGGIEIETVEDRAMLSRLGVSNVQNDTMSGGEETRAKIAAAFSQQVHG  120

Query  121  ILADEPTSHLDLNGIDLLIGQLKAFDGALLVISHDRYFLDMVVDKIWELKDGKITEYWGG  180
            ILADEPTSHLDLNGIDLLIGQLKAFDGALLVISHDRYFLDMVVDKIWELKDGKITEYWGG
Sbjct  121  ILADEPTSHLDLNGIDLLIGQLKAFDGALLVISHDRYFLDMVVDKIWELKDGKITEYWGG  180

Query  181  YSDYLRQKEEERQHQAVEYELMMKERERLESAVQEKRQQANRLDNKKKGEKSKNSTESAG  240
            YSDYLRQKEEERQHQAVEYELMMKERERLESAVQEKRQQANRLDNKKKGEKSKNSTESAG
Sbjct  181  YSDYLRQKEEERQHQAVEYELMMKERERLESAVQEKRQQANRLDNKKKGEKSKNSTESAG  240

Query  241  RLGHAKMTGTKQRKLYQAAKSMEKRLAALEDIQAPEHLRSIRFRQSSALELHNKFPITAD  300
            RLGHAKMTGTKQRKLYQAAKSMEKRLAALEDIQAPEHLRSIRFRQSSALELHNKFPITAD
Sbjct  241  RLGHAKMTGTKQRKLYQAAKSMEKRLAALEDIQAPEHLRSIRFRQSSALELHNKFPITAD  300

Query  301  GLSLKFGSRTIFDDANFIIPLGAKVAITGSNGTGKTSLLKMISERADGLTISPKAEIGYF  360
            GLSLKFGSRTIFDDANFIIPLGAKVAITGSNGTGKTSLLKMISERADGLTISPKAEIGYF
Sbjct  301  GLSLKFGSRTIFDDANFIIPLGAKVAITGSNGTGKTSLLKMISERADGLTISPKAEIGYF  360

Query  361  TQTGYKFNTHKSVLSFMQEECEYTVAEIRAVLASMGIGANDIQKNLSDLSGGEIIKLLLS  420
            TQTGYKFNTHKSVLSFMQEECEYTVAEIRAVLASMGIGANDIQKNLSDLSGGEIIKLLLS
Sbjct  361  TQTGYKFNTHKSVLSFMQEECEYTVAEIRAVLASMGIGANDIQKNLSDLSGGEIIKLLLS  420

Query  421  KMLLGKYNILLMDEPGNYLDLKSIAALETMMKSYAGTIIFVSHDKQLVDNIADIIYEIKD  480
            KMLLGKYNILLMDEPGNYLDLKSIAALETMMKSYAGTIIFVSHDKQLVDNIADIIYEIKD
Sbjct  421  KMLLGKYNILLMDEPGNYLDLKSIAALETMMKSYAGTIIFVSHDKQLVDNIADIIYEIKD  480

Query  481  HKIIKTFERDC  491
            HKIIKTFERDC
Sbjct  481  HKIIKTFERDC  491

5) M3Q_2654 in NC_018706


> NC_016808_R1|79|G72|378774001|YP_005176244.1|Pasteurella_multocida_36950|+|67348..68823|msr(E)|Pmu_03460|macrolide 
efflux 
protein
Length=491

 Score =  793 bits (3001),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 491/491 (100%), Positives = 491/491 (100%), Gaps = 0/491 (0%)

Query  1    MSLIIKARNIRLDYAGRDVLDIDELEIHSYDRIGLVGDNGAGKSSLLKVLNGEIVLAEAT  60
            MSLIIKARNIRLDYAGRDVLDIDELEIHSYDRIGLVGDNGAGKSSLLKVLNGEIVLAEAT
Sbjct  1    MSLIIKARNIRLDYAGRDVLDIDELEIHSYDRIGLVGDNGAGKSSLLKVLNGEIVLAEAT  60

Query  61   LQRFGDFAHISQLGGIEIETVEDRAMLSRLGVSNVQNDTMSGGEETRAKIAAAFSQQVHG  120
            LQRFGDFAHISQLGGIEIETVEDRAMLSRLGVSNVQNDTMSGGEETRAKIAAAFSQQVHG
Sbjct  61   LQRFGDFAHISQLGGIEIETVEDRAMLSRLGVSNVQNDTMSGGEETRAKIAAAFSQQVHG  120

Query  121  ILADEPTSHLDLNGIDLLIGQLKAFDGALLVISHDRYFLDMVVDKIWELKDGKITEYWGG  180
            ILADEPTSHLDLNGIDLLIGQLKAFDGALLVISHDRYFLDMVVDKIWELKDGKITEYWGG
Sbjct  121  ILADEPTSHLDLNGIDLLIGQLKAFDGALLVISHDRYFLDMVVDKIWELKDGKITEYWGG  180

Query  181  YSDYLRQKEEERQHQAVEYELMMKERERLESAVQEKRQQANRLDNKKKGEKSKNSTESAG  240
            YSDYLRQKEEERQHQAVEYELMMKERERLESAVQEKRQQANRLDNKKKGEKSKNSTESAG
Sbjct  181  YSDYLRQKEEERQHQAVEYELMMKERERLESAVQEKRQQANRLDNKKKGEKSKNSTESAG  240

Query  241  RLGHAKMTGTKQRKLYQAAKSMEKRLAALEDIQAPEHLRSIRFRQSSALELHNKFPITAD  300
            RLGHAKMTGTKQRKLYQAAKSMEKRLAALEDIQAPEHLRSIRFRQSSALELHNKFPITAD
Sbjct  241  RLGHAKMTGTKQRKLYQAAKSMEKRLAALEDIQAPEHLRSIRFRQSSALELHNKFPITAD  300

Query  301  GLSLKFGSRTIFDDANFIIPLGAKVAITGSNGTGKTSLLKMISERADGLTISPKAEIGYF  360
            GLSLKFGSRTIFDDANFIIPLGAKVAITGSNGTGKTSLLKMISERADGLTISPKAEIGYF
Sbjct  301  GLSLKFGSRTIFDDANFIIPLGAKVAITGSNGTGKTSLLKMISERADGLTISPKAEIGYF  360

Query  361  TQTGYKFNTHKSVLSFMQEECEYTVAEIRAVLASMGIGANDIQKNLSDLSGGEIIKLLLS  420
            TQTGYKFNTHKSVLSFMQEECEYTVAEIRAVLASMGIGANDIQKNLSDLSGGEIIKLLLS
Sbjct  361  TQTGYKFNTHKSVLSFMQEECEYTVAEIRAVLASMGIGANDIQKNLSDLSGGEIIKLLLS  420

Query  421  KMLLGKYNILLMDEPGNYLDLKSIAALETMMKSYAGTIIFVSHDKQLVDNIADIIYEIKD  480
            KMLLGKYNILLMDEPGNYLDLKSIAALETMMKSYAGTIIFVSHDKQLVDNIADIIYEIKD
Sbjct  421  KMLLGKYNILLMDEPGNYLDLKSIAALETMMKSYAGTIIFVSHDKQLVDNIADIIYEIKD  480

Query  481  HKIIKTFERDC  491
            HKIIKTFERDC
Sbjct  481  HKIIKTFERDC  491

6) WQG_1100 in NC_020515


> NC_016808_R1|79|G72|378774001|YP_005176244.1|Pasteurella_multocida_36950|+|67348..68823|msr(E)|Pmu_03460|macrolide 
efflux 
protein
Length=491

 Score =  793 bits (3001),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 491/491 (100%), Positives = 491/491 (100%), Gaps = 0/491 (0%)

Query  1    MSLIIKARNIRLDYAGRDVLDIDELEIHSYDRIGLVGDNGAGKSSLLKVLNGEIVLAEAT  60
            MSLIIKARNIRLDYAGRDVLDIDELEIHSYDRIGLVGDNGAGKSSLLKVLNGEIVLAEAT
Sbjct  1    MSLIIKARNIRLDYAGRDVLDIDELEIHSYDRIGLVGDNGAGKSSLLKVLNGEIVLAEAT  60

Query  61   LQRFGDFAHISQLGGIEIETVEDRAMLSRLGVSNVQNDTMSGGEETRAKIAAAFSQQVHG  120
            LQRFGDFAHISQLGGIEIETVEDRAMLSRLGVSNVQNDTMSGGEETRAKIAAAFSQQVHG
Sbjct  61   LQRFGDFAHISQLGGIEIETVEDRAMLSRLGVSNVQNDTMSGGEETRAKIAAAFSQQVHG  120

Query  121  ILADEPTSHLDLNGIDLLIGQLKAFDGALLVISHDRYFLDMVVDKIWELKDGKITEYWGG  180
            ILADEPTSHLDLNGIDLLIGQLKAFDGALLVISHDRYFLDMVVDKIWELKDGKITEYWGG
Sbjct  121  ILADEPTSHLDLNGIDLLIGQLKAFDGALLVISHDRYFLDMVVDKIWELKDGKITEYWGG  180

Query  181  YSDYLRQKEEERQHQAVEYELMMKERERLESAVQEKRQQANRLDNKKKGEKSKNSTESAG  240
            YSDYLRQKEEERQHQAVEYELMMKERERLESAVQEKRQQANRLDNKKKGEKSKNSTESAG
Sbjct  181  YSDYLRQKEEERQHQAVEYELMMKERERLESAVQEKRQQANRLDNKKKGEKSKNSTESAG  240

Query  241  RLGHAKMTGTKQRKLYQAAKSMEKRLAALEDIQAPEHLRSIRFRQSSALELHNKFPITAD  300
            RLGHAKMTGTKQRKLYQAAKSMEKRLAALEDIQAPEHLRSIRFRQSSALELHNKFPITAD
Sbjct  241  RLGHAKMTGTKQRKLYQAAKSMEKRLAALEDIQAPEHLRSIRFRQSSALELHNKFPITAD  300

Query  301  GLSLKFGSRTIFDDANFIIPLGAKVAITGSNGTGKTSLLKMISERADGLTISPKAEIGYF  360
            GLSLKFGSRTIFDDANFIIPLGAKVAITGSNGTGKTSLLKMISERADGLTISPKAEIGYF
Sbjct  301  GLSLKFGSRTIFDDANFIIPLGAKVAITGSNGTGKTSLLKMISERADGLTISPKAEIGYF  360

Query  361  TQTGYKFNTHKSVLSFMQEECEYTVAEIRAVLASMGIGANDIQKNLSDLSGGEIIKLLLS  420
            TQTGYKFNTHKSVLSFMQEECEYTVAEIRAVLASMGIGANDIQKNLSDLSGGEIIKLLLS
Sbjct  361  TQTGYKFNTHKSVLSFMQEECEYTVAEIRAVLASMGIGANDIQKNLSDLSGGEIIKLLLS  420

Query  421  KMLLGKYNILLMDEPGNYLDLKSIAALETMMKSYAGTIIFVSHDKQLVDNIADIIYEIKD  480
            KMLLGKYNILLMDEPGNYLDLKSIAALETMMKSYAGTIIFVSHDKQLVDNIADIIYEIKD
Sbjct  421  KMLLGKYNILLMDEPGNYLDLKSIAALETMMKSYAGTIIFVSHDKQLVDNIADIIYEIKD  480

Query  481  HKIIKTFERDC  491
            HKIIKTFERDC
Sbjct  481  HKIIKTFERDC  491

7) A225_R1p0735 in NC_018107


> NC_016808_R1|79|G72|378774001|YP_005176244.1|Pasteurella_multocida_36950|+|67348..68823|msr(E)|Pmu_03460|macrolide 
efflux 
protein
Length=491

 Score =  793 bits (3001),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 491/491 (100%), Positives = 491/491 (100%), Gaps = 0/491 (0%)

Query  1    MSLIIKARNIRLDYAGRDVLDIDELEIHSYDRIGLVGDNGAGKSSLLKVLNGEIVLAEAT  60
            MSLIIKARNIRLDYAGRDVLDIDELEIHSYDRIGLVGDNGAGKSSLLKVLNGEIVLAEAT
Sbjct  1    MSLIIKARNIRLDYAGRDVLDIDELEIHSYDRIGLVGDNGAGKSSLLKVLNGEIVLAEAT  60

Query  61   LQRFGDFAHISQLGGIEIETVEDRAMLSRLGVSNVQNDTMSGGEETRAKIAAAFSQQVHG  120
            LQRFGDFAHISQLGGIEIETVEDRAMLSRLGVSNVQNDTMSGGEETRAKIAAAFSQQVHG
Sbjct  61   LQRFGDFAHISQLGGIEIETVEDRAMLSRLGVSNVQNDTMSGGEETRAKIAAAFSQQVHG  120

Query  121  ILADEPTSHLDLNGIDLLIGQLKAFDGALLVISHDRYFLDMVVDKIWELKDGKITEYWGG  180
            ILADEPTSHLDLNGIDLLIGQLKAFDGALLVISHDRYFLDMVVDKIWELKDGKITEYWGG
Sbjct  121  ILADEPTSHLDLNGIDLLIGQLKAFDGALLVISHDRYFLDMVVDKIWELKDGKITEYWGG  180

Query  181  YSDYLRQKEEERQHQAVEYELMMKERERLESAVQEKRQQANRLDNKKKGEKSKNSTESAG  240
            YSDYLRQKEEERQHQAVEYELMMKERERLESAVQEKRQQANRLDNKKKGEKSKNSTESAG
Sbjct  181  YSDYLRQKEEERQHQAVEYELMMKERERLESAVQEKRQQANRLDNKKKGEKSKNSTESAG  240

Query  241  RLGHAKMTGTKQRKLYQAAKSMEKRLAALEDIQAPEHLRSIRFRQSSALELHNKFPITAD  300
            RLGHAKMTGTKQRKLYQAAKSMEKRLAALEDIQAPEHLRSIRFRQSSALELHNKFPITAD
Sbjct  241  RLGHAKMTGTKQRKLYQAAKSMEKRLAALEDIQAPEHLRSIRFRQSSALELHNKFPITAD  300

Query  301  GLSLKFGSRTIFDDANFIIPLGAKVAITGSNGTGKTSLLKMISERADGLTISPKAEIGYF  360
            GLSLKFGSRTIFDDANFIIPLGAKVAITGSNGTGKTSLLKMISERADGLTISPKAEIGYF
Sbjct  301  GLSLKFGSRTIFDDANFIIPLGAKVAITGSNGTGKTSLLKMISERADGLTISPKAEIGYF  360

Query  361  TQTGYKFNTHKSVLSFMQEECEYTVAEIRAVLASMGIGANDIQKNLSDLSGGEIIKLLLS  420
            TQTGYKFNTHKSVLSFMQEECEYTVAEIRAVLASMGIGANDIQKNLSDLSGGEIIKLLLS
Sbjct  361  TQTGYKFNTHKSVLSFMQEECEYTVAEIRAVLASMGIGANDIQKNLSDLSGGEIIKLLLS  420

Query  421  KMLLGKYNILLMDEPGNYLDLKSIAALETMMKSYAGTIIFVSHDKQLVDNIADIIYEIKD  480
            KMLLGKYNILLMDEPGNYLDLKSIAALETMMKSYAGTIIFVSHDKQLVDNIADIIYEIKD
Sbjct  421  KMLLGKYNILLMDEPGNYLDLKSIAALETMMKSYAGTIIFVSHDKQLVDNIADIIYEIKD  480

Query  481  HKIIKTFERDC  491
            HKIIKTFERDC
Sbjct  481  HKIIKTFERDC  491

8) A225_R1p0475 in NC_018107


> NC_016808_R1|79|G72|378774001|YP_005176244.1|Pasteurella_multocida_36950|+|67348..68823|msr(E)|Pmu_03460|macrolide 
efflux 
protein
Length=491

 Score =  793 bits (3001),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 491/491 (100%), Positives = 491/491 (100%), Gaps = 0/491 (0%)

Query  1    MSLIIKARNIRLDYAGRDVLDIDELEIHSYDRIGLVGDNGAGKSSLLKVLNGEIVLAEAT  60
            MSLIIKARNIRLDYAGRDVLDIDELEIHSYDRIGLVGDNGAGKSSLLKVLNGEIVLAEAT
Sbjct  1    MSLIIKARNIRLDYAGRDVLDIDELEIHSYDRIGLVGDNGAGKSSLLKVLNGEIVLAEAT  60

Query  61   LQRFGDFAHISQLGGIEIETVEDRAMLSRLGVSNVQNDTMSGGEETRAKIAAAFSQQVHG  120
            LQRFGDFAHISQLGGIEIETVEDRAMLSRLGVSNVQNDTMSGGEETRAKIAAAFSQQVHG
Sbjct  61   LQRFGDFAHISQLGGIEIETVEDRAMLSRLGVSNVQNDTMSGGEETRAKIAAAFSQQVHG  120

Query  121  ILADEPTSHLDLNGIDLLIGQLKAFDGALLVISHDRYFLDMVVDKIWELKDGKITEYWGG  180
            ILADEPTSHLDLNGIDLLIGQLKAFDGALLVISHDRYFLDMVVDKIWELKDGKITEYWGG
Sbjct  121  ILADEPTSHLDLNGIDLLIGQLKAFDGALLVISHDRYFLDMVVDKIWELKDGKITEYWGG  180

Query  181  YSDYLRQKEEERQHQAVEYELMMKERERLESAVQEKRQQANRLDNKKKGEKSKNSTESAG  240
            YSDYLRQKEEERQHQAVEYELMMKERERLESAVQEKRQQANRLDNKKKGEKSKNSTESAG
Sbjct  181  YSDYLRQKEEERQHQAVEYELMMKERERLESAVQEKRQQANRLDNKKKGEKSKNSTESAG  240

Query  241  RLGHAKMTGTKQRKLYQAAKSMEKRLAALEDIQAPEHLRSIRFRQSSALELHNKFPITAD  300
            RLGHAKMTGTKQRKLYQAAKSMEKRLAALEDIQAPEHLRSIRFRQSSALELHNKFPITAD
Sbjct  241  RLGHAKMTGTKQRKLYQAAKSMEKRLAALEDIQAPEHLRSIRFRQSSALELHNKFPITAD  300

Query  301  GLSLKFGSRTIFDDANFIIPLGAKVAITGSNGTGKTSLLKMISERADGLTISPKAEIGYF  360
            GLSLKFGSRTIFDDANFIIPLGAKVAITGSNGTGKTSLLKMISERADGLTISPKAEIGYF
Sbjct  301  GLSLKFGSRTIFDDANFIIPLGAKVAITGSNGTGKTSLLKMISERADGLTISPKAEIGYF  360

Query  361  TQTGYKFNTHKSVLSFMQEECEYTVAEIRAVLASMGIGANDIQKNLSDLSGGEIIKLLLS  420
            TQTGYKFNTHKSVLSFMQEECEYTVAEIRAVLASMGIGANDIQKNLSDLSGGEIIKLLLS
Sbjct  361  TQTGYKFNTHKSVLSFMQEECEYTVAEIRAVLASMGIGANDIQKNLSDLSGGEIIKLLLS  420

Query  421  KMLLGKYNILLMDEPGNYLDLKSIAALETMMKSYAGTIIFVSHDKQLVDNIADIIYEIKD  480
            KMLLGKYNILLMDEPGNYLDLKSIAALETMMKSYAGTIIFVSHDKQLVDNIADIIYEIKD
Sbjct  421  KMLLGKYNILLMDEPGNYLDLKSIAALETMMKSYAGTIIFVSHDKQLVDNIADIIYEIKD  480

Query  481  HKIIKTFERDC  491
            HKIIKTFERDC
Sbjct  481  HKIIKTFERDC  491

9) msr(E) in NC_016808


> NC_016808_R1|79|G72|378774001|YP_005176244.1|Pasteurella_multocida_36950|+|67348..68823|msr(E)|Pmu_03460|macrolide 
efflux 
protein
Length=491

 Score =  793 bits (3001),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 491/491 (100%), Positives = 491/491 (100%), Gaps = 0/491 (0%)

Query  1    MSLIIKARNIRLDYAGRDVLDIDELEIHSYDRIGLVGDNGAGKSSLLKVLNGEIVLAEAT  60
            MSLIIKARNIRLDYAGRDVLDIDELEIHSYDRIGLVGDNGAGKSSLLKVLNGEIVLAEAT
Sbjct  1    MSLIIKARNIRLDYAGRDVLDIDELEIHSYDRIGLVGDNGAGKSSLLKVLNGEIVLAEAT  60

Query  61   LQRFGDFAHISQLGGIEIETVEDRAMLSRLGVSNVQNDTMSGGEETRAKIAAAFSQQVHG  120
            LQRFGDFAHISQLGGIEIETVEDRAMLSRLGVSNVQNDTMSGGEETRAKIAAAFSQQVHG
Sbjct  61   LQRFGDFAHISQLGGIEIETVEDRAMLSRLGVSNVQNDTMSGGEETRAKIAAAFSQQVHG  120

Query  121  ILADEPTSHLDLNGIDLLIGQLKAFDGALLVISHDRYFLDMVVDKIWELKDGKITEYWGG  180
            ILADEPTSHLDLNGIDLLIGQLKAFDGALLVISHDRYFLDMVVDKIWELKDGKITEYWGG
Sbjct  121  ILADEPTSHLDLNGIDLLIGQLKAFDGALLVISHDRYFLDMVVDKIWELKDGKITEYWGG  180

Query  181  YSDYLRQKEEERQHQAVEYELMMKERERLESAVQEKRQQANRLDNKKKGEKSKNSTESAG  240
            YSDYLRQKEEERQHQAVEYELMMKERERLESAVQEKRQQANRLDNKKKGEKSKNSTESAG
Sbjct  181  YSDYLRQKEEERQHQAVEYELMMKERERLESAVQEKRQQANRLDNKKKGEKSKNSTESAG  240

Query  241  RLGHAKMTGTKQRKLYQAAKSMEKRLAALEDIQAPEHLRSIRFRQSSALELHNKFPITAD  300
            RLGHAKMTGTKQRKLYQAAKSMEKRLAALEDIQAPEHLRSIRFRQSSALELHNKFPITAD
Sbjct  241  RLGHAKMTGTKQRKLYQAAKSMEKRLAALEDIQAPEHLRSIRFRQSSALELHNKFPITAD  300

Query  301  GLSLKFGSRTIFDDANFIIPLGAKVAITGSNGTGKTSLLKMISERADGLTISPKAEIGYF  360
            GLSLKFGSRTIFDDANFIIPLGAKVAITGSNGTGKTSLLKMISERADGLTISPKAEIGYF
Sbjct  301  GLSLKFGSRTIFDDANFIIPLGAKVAITGSNGTGKTSLLKMISERADGLTISPKAEIGYF  360

Query  361  TQTGYKFNTHKSVLSFMQEECEYTVAEIRAVLASMGIGANDIQKNLSDLSGGEIIKLLLS  420
            TQTGYKFNTHKSVLSFMQEECEYTVAEIRAVLASMGIGANDIQKNLSDLSGGEIIKLLLS
Sbjct  361  TQTGYKFNTHKSVLSFMQEECEYTVAEIRAVLASMGIGANDIQKNLSDLSGGEIIKLLLS  420

Query  421  KMLLGKYNILLMDEPGNYLDLKSIAALETMMKSYAGTIIFVSHDKQLVDNIADIIYEIKD  480
            KMLLGKYNILLMDEPGNYLDLKSIAALETMMKSYAGTIIFVSHDKQLVDNIADIIYEIKD
Sbjct  421  KMLLGKYNILLMDEPGNYLDLKSIAALETMMKSYAGTIIFVSHDKQLVDNIADIIYEIKD  480

Query  481  HKIIKTFERDC  491
            HKIIKTFERDC
Sbjct  481  HKIIKTFERDC  491

10) GYMC10_3536 in NC_013406


> NC_016808_R1|79|G72|378774001|YP_005176244.1|Pasteurella_multocida_36950|+|67348..68823|msr(E)|Pmu_03460|macrolide 
efflux 
protein
Length=491

 Score =  534 bits (2014),  Expect = 6e-153, Method: Compositional matrix adjust.
 Identities = 292/485 (61%), Positives = 404/485 (84%), Gaps = 0/485 (0%)

Query  1    MGFLIKAKDMVVEYSGRDVLDIDGLELYDYDRIGLVGANGAGKSTLLKALLGEIPLSQGT  60
            M+++IKA+++ ++Y+GRDVLDID LE+  YDRIGLVG NGAGKS+LLK L GEI L+++T
Sbjct  1    MSLIIKARNIRLDYAGRDVLDIDELEIHSYDRIGLVGDNGAGKSSLLKVLNGEIVLAEAT  60

Query  61   VIREGNFRYIPQLDDVIVQEIQDYALIGKLGIESCEAEYMSGGEETRLKIAQALSGEVHG  120
            + R G+F  I+QL+++ ++ ++D A++++LG+ + + + MSGGEETR KIA A+S +VHG
Sbjct  61   LQRFGDFAHISQLGGIEIETVEDRAMLSRLGVSNVQNDTMSGGEETRAKIAAAFSQQVHG  120

Query  121  IFADEPTCHLDRDGIDFLIHQLKYYSGALLIISHDRYFLDQVVDKIWELNEGKITEYWGG  180
            I+ADEPT HLD +GID+LI QLK + GALL+ISHDRYFLD VVDKIWEL++GKITEYWGG
Sbjct  121  ILADEPTSHLDLNGIDLLIGQLKAFDGALLVISHDRYFLDMVVDKIWELKDGKITEYWGG  180

Query  181  YSDYLRQKEEERHSQAAKYKQFTAERERLEKAITEKLSQARKVDQKAKGASRKNSSEGGG  240
            YSDYLRQKEEER+ QA  Y     ERERLE A+ EK  QA ++D+K KG   KNS+E++G
Sbjct  181  YSDYLRQKEEERQHQAVEYELMMKERERLESAVQEKRQQANRLDNKKKGEKSKNSTESAG  240

Query  241  RLAHQKSTGSKQKKLHNAAKNMEHRIQALGEVKPPEAMRSIRFRQSKALELHHPFPITGK  300
            RL+H K TG+KQ+KL +AAK+ME R+ AL ++++PE +RSIRFRQS ALELH+ FPIT+ 
Sbjct  241  RLGHAKMTGTKQRKLYQAAKSMEKRLAALEDIQAPEHLRSIRFRQSSALELHNKFPITAD  300

Query  301  DICKQFEGKEIFEEATFQFPLGAKIAVTGANGSGKTTLFKMILHREHGISVSPKAEIGYF  360
            ++  +F ++ IF++A F +PLGAK+A+TG+NG+GKT+L+KMI +R +G+++SPKAEIGYF
Sbjct  301  GLSLKFGSRTIFDDANFIIPLGAKVAITGSNGTGKTSLLKMISERADGLTISPKAEIGYF  360

Query  361  AQTGYKFDRDQGVMEFMLEDSDYEVSDIRAVLASMGFSQQDVRKSLSVLSGGEIMKLQLA  420
            +QTGYKF+ +++V+ FM E+ +Y V++IRAVLASMG++ +D++K+LS LSGGEI+KL L+
Sbjct  361  TQTGYKFNTHKSVLSFMQEECEYTVAEIRAVLASMGIGANDIQKNLSDLSGGEIIKLLLS  420

Query  421  KMLLGRYNILLMDEPSNFLDLPAVEALEQLMMHYAGTIIFISHDVRLIENVADTVYVIED  480
            KMLLG+YNILLMDEP+N+LDL ++ ALE +M  YAGTIIF+SHD +L++N+AD +Y I D
Sbjct  421  KMLLGKYNILLMDEPGNYLDLKSIAALETMMKSYAGTIIFVSHDKQLVDNIADIIYEIKD  480

Query  481  KKIIQ  485
             KII+
Sbjct  481  HKIIK  485

11) Desmer_1358 in NC_018515


> NC_016808_R1|79|G72|378774001|YP_005176244.1|Pasteurella_multocida_36950|+|67348..68823|msr(E)|Pmu_03460|macrolide 
efflux 
protein
Length=491

 Score =  528 bits (1991),  Expect = 4e-151, Method: Compositional matrix adjust.
 Identities = 304/483 (63%), Positives = 404/483 (84%), Gaps = 0/483 (0%)

Query  1    MELIVKAKDIRLEYTGRDVLDIDELELYEYDRIGLVGANGAGKSSLLKVLLGELTLPGCK  60
            M LI+KA++IRL+Y+GRDVLDIDELE+  YDRIGLVG NGAGKSSLLKVL GE+ L+   
Sbjct  1    MSLIIKARNIRLDYAGRDVLDIDELEIHSYDRIGLVGDNGAGKSSLLKVLNGEIVLAEAT  60

Query  61   INRLGRLAYIPQLEEAILEEVKDFALIGKLGASQIAVQTMSGGEETRLKIAQALSEQVHG  120
            ++R+G +A I+QL    +E V D A++++LG S++  +TMSGGEETR KIA A+S+QVHG
Sbjct  61   LQRFGDFAHISQLGGIEIETVEDRAMLSRLGVSNVQNDTMSGGEETRAKIAAAFSQQVHG  120

Query  121  ILADEPTSHLDREGMDFLIGQLKYFSGALLIISHDRYFLDEVVDKIWELKEGKITEYWGN  180
            ILADEPTSHLD +G+D+LIGQLK F GALL+ISHDRYFLD VVDKIWELK+GKITEYWG 
Sbjct  121  ILADEPTSHLDLNGIDLLIGQLKAFDGALLVISHDRYFLDMVVDKIWELKDGKITEYWGG  180

Query  181  YSDYLRHKGEERQSQAARYEQLVaergrleraaeekrkqarkLDQKAKGAAKKNSSESGG  240
            YSDYLR+K EERQ QA  YE ++ ER RLE A +EKR+QA +LD+K KG   KNS+ES+G
Sbjct  181  YSDYLRQKEEERQHQAVEYELMMKERERLESAVQEKRQQANRLDNKKKGEKSKNSTESAG  240

Query  241  RLGHQKTMGSKQKTLFNAAKAMEHRLAALGEAEAPESIRTMRFRQSKTLELHNPYPIMGT  300
            RLGH K  G+KQ+ L++AAK+ME RLAAL + +APE +R++RFRQS +LELHN +PI + 
Sbjct  241  RLGHAKMTGTKQRKLYQAAKSMEKRLAALEDIQAPEHLRSIRFRQSSALELHNKFPITAD  300

Query  301  EIKKSFGDKVILEKTAFSIPLGAKAALTGGNGAGKTTLIQMILNREEGISISPKAEIGYF  360
             +   FG + I++ + F IPLGAK A+TG+NG+GKT+L++MI +R +G++ISPKAEIGYF
Sbjct  301  GLSLKFGSRTIFDDANFIIPLGAKVAITGSNGTGKTSLLKMISERADGLTISPKAEIGYF  360

Query  361  AQTGYKYNRNQEVMEFMQEDCDYNISEIRSVLASLGFIQHDLGKRLAVLSGGEMIKLQLA  420
            +QTGYK+N ++ V+ FMQE+C+Y ++EIR+VLAS+G+  +D+ K L+ LSGGE+IKL L+
Sbjct  361  TQTGYKFNTHKSVLSFMQEECEYTVAEIRAVLASMGIGANDIQKNLSDLSGGEIIKLLLS  420

Query  421  KMLMGRYNILLMDEPSNFLDLPGIEALEVLMKGYAGTIVFITHDQRLLDNVADMIYEIKD  480
            KML+G+YNILLMDEP+N+LDL +I ALE +MK+YAGTI+F++HD++L+DN+AD+IYEIKD
Sbjct  421  KMLLGKYNILLMDEPGNYLDLKSIAALETMMKSYAGTIIFVSHDKQLVDNIADIIYEIKD  480

Query  481  NRL  483
            +++
Sbjct  481  HKI  483

12) Desru_2756 in NC_015589


> NC_016808_R1|79|G72|378774001|YP_005176244.1|Pasteurella_multocida_36950|+|67348..68823|msr(E)|Pmu_03460|macrolide 
efflux 
protein
Length=491

 Score =  525 bits (1980),  Expect = 3e-150, Method: Compositional matrix adjust.
 Identities = 296/483 (62%), Positives = 409/483 (85%), Gaps = 0/483 (0%)

Query  1    MELLLKASDICVEYTGREVLDINELELYDYDRIGLIGSNGAGKSTLLKVLLGEFTPPGCR  60
            M L++KA +I ++Y+GR+VLDI+ELE+  YDRIGL+G NGAGKS+LLKVL GE+  +   
Sbjct  1    MSLIIKARNIRLDYAGRDVLDIDELEIHSYDRIGLVGDNGAGKSSLLKVLNGEIVLAEAT  60

Query  61   VKRSGNFAHIPQLEEAHVQCSTDHALFSKLGVNKLDKQNMSGGEETRLKVAQALSCQVHG  120
            ++R G+FAHI+QL   +++   D+A++S+LGV++++++ MSGGEETR K+A A+S QVHG
Sbjct  61   LQRFGDFAHISQLGGIEIETVEDRAMLSRLGVSNVQNDTMSGGEETRAKIAAAFSQQVHG  120

Query  121  IFADEPTCHLDREGIDFLIGQLQYFSGALLIISHDRYFLDAVVNKIWELKDGKITEYWGN  180
            I+ADEPT HLD +GID+LIGQL+ F GALL+ISHDRYFLD VV+KIWELKDGKITEYWG 
Sbjct  121  ILADEPTSHLDLNGIDLLIGQLKAFDGALLVISHDRYFLDMVVDKIWELKDGKITEYWGG  180

Query  181  YSNYLHQKEEERRNQAVRYEQFVSererleraaeekrkqarkIDQKSKETAKKGMTESGS  240
            YS+YL+QKEEER++QAV YE  + ERERLE A +EKR+QA ++D+K K    K  TES++
Sbjct  181  YSDYLRQKEEERQHQAVEYELMMKERERLESAVQEKRQQANRLDNKKKGEKSKNSTESAG  240

Query  241  RLGHQKTMGSKQKSLYNSAKSMEHRMAAMEEVQAPEKVRTVRFRQSQALALHNPYPITGT  300
            RLGH K  G+KQ+ LY++AKSME R+AA+E++QAPE +R++RFRQS AL LHN +PIT+ 
Sbjct  241  RLGHAKMTGTKQRKLYQAAKSMEKRLAALEDIQAPEHLRSIRFRQSSALELHNKFPITAD  300

Query  301  EINKRFADKVIFDSTSFQIPLGGKVAFTGGNGTGKTTLFHMILNREDGISVSPKAEIGYF  360
             ++ +F+ + IFD ++F IPLG+KVA+TG+NGTGKT+L+ MI +R DG+++SPKAEIGYF
Sbjct  301  GLSLKFGSRTIFDDANFIIPLGAKVAITGSNGTGKTSLLKMISERADGLTISPKAEIGYF  360

Query  361  AQSGYKFNRDQCVIAFMEKNCDYQQSEIRSVLASMGFSQNDIRKNLSVLSGGEIIKLLLA  420
            +Q+GYKFN ++ V++FM+ +C+Y  +EIR+VLASMG++ NDI+KNLS LSGGEIIKLLL+
Sbjct  361  TQTGYKFNTHKSVLSFMQEECEYTVAEIRAVLASMGIGANDIQKNLSDLSGGEIIKLLLS  420

Query  421  KMFLGRYNILLMDEPSNYLDLPSVEALEALMKNYGGTILFISHDQRMLENVADRIYTIED  480
            KM+LG+YNILLMDEP+NYLDL S+ ALE++MK+Y+GTI+F+SHD+++++N+AD IY I D
Sbjct  421  KMLLGKYNILLMDEPGNYLDLKSIAALETMMKSYAGTIIFVSHDKQLVDNIADIIYEIKD  480

Query  481  RRL  483
            +++
Sbjct  481  HKI  483

13) HMPREF0424_0873 in NC_013721


> NC_016808_R1|79|G72|378774001|YP_005176244.1|Pasteurella_multocida_36950|+|67348..68823|msr(E)|Pmu_03460|macrolide 
efflux 
protein
Length=491

 Score =  517 bits (1949),  Expect = 9e-148, Method: Compositional matrix adjust.
 Identities = 297/483 (62%), Positives = 407/483 (85%), Gaps = 0/483 (0%)

Query  1    MELILKAKDIRVEFKGRDVLDINELEVYDYDRIGLVGANGAGKSTLLRVLLGELTPPGCK  60
            M LI+KA++IR+++ GRDVLDI+ELE+  YDRIGLVG NGAGKS+LL+VL GE+  +   
Sbjct  1    MSLIIKARNIRLDYAGRDVLDIDELEIHSYDRIGLVGDNGAGKSSLLKVLNGEIVLAEAT  60

Query  61   MNRLGELAYIPQLDEVTLQEEKDFALVGKLGVEQLNIQTMSGGEETRLKIAQALSAQVHG  120
            ++R+G++A I+QL+ + ++   D A++++LGV +++ +TMSGGEETR KIA A+S QVHG
Sbjct  61   LQRFGDFAHISQLGGIEIETVEDRAMLSRLGVSNVQNDTMSGGEETRAKIAAAFSQQVHG  120

Query  121  ILADEPTSHLDREGIDFLIGQLKYFTGALLVISHDRYFLDEIVDKIWELKDGKITEYWGN  180
            ILADEPTSHLD +GID+LIGQLK F GALLVISHDRYFLD +VDKIWELKDGKITEYWG 
Sbjct  121  ILADEPTSHLDLNGIDLLIGQLKAFDGALLVISHDRYFLDMVVDKIWELKDGKITEYWGG  180

Query  181  YSDYLRQKEEERKSQAAEYEQFiaerarleraaeekrkqarkieqkakGSSKKKSTEDGG  240
            YSDYLRQKEEER+ QA EYE  + ER RLE A +EKR+QA ++++K KG   K+STE +G
Sbjct  181  YSDYLRQKEEERQHQAVEYELMMKERERLESAVQEKRQQANRLDNKKKGEKSKNSTESAG  240

Query  241  RLAHQKSIGSKEKKMYNAAKTLEHRIAALGKVEAPEGIRRIRFRQSKALELHNPYPIVGA  300
            RL+H K  G+K++K+Y+AAK++E R+AAL  ++APE +R IRFRQS ALELHN +PI + 
Sbjct  241  RLGHAKMTGTKQRKLYQAAKSMEKRLAALEDIQAPEHLRSIRFRQSSALELHNKFPITAD  300

Query  301  EINKVFGDKALFENASFQIPLGAKVALTGGNGIGKTTLIQMILNHEEGISISPKAKIGYF  360
             ++  FG +++F++A+F IPLGAKVA+TG+NG GKT+L++MI ++ +G++ISPKA IGYF
Sbjct  301  GLSLKFGSRTIFDDANFIIPLGAKVAITGSNGTGKTSLLKMISERADGLTISPKAEIGYF  360

Query  361  AQNGYKYNSNQNVMEFMQKDCDYNISEIRSVLASMGFKQNDIGKSLSVLSGGEIIKLLLA  420
            +Q GYK+N++++V+ FMQ +C+Y ++EIR+VLASMG+  NDI K+LS LSGGEIIKLLL+
Sbjct  361  TQTGYKFNTHKSVLSFMQEECEYTVAEIRAVLASMGIGANDIQKNLSDLSGGEIIKLLLS  420

Query  421  KMLMGRYNILIMDEPSNFLDIPSLEALEILMKEYTGTIVFITHDKRLLENVADVVYEIRD  480
            KML+G+YNIL+MDEP+N+LD+ S+ ALE +MK Y+GTI+F++HDK+L++N+AD++YEI+D
Sbjct  421  KMLLGKYNILLMDEPGNYLDLKSIAALETMMKSYAGTIIFVSHDKQLVDNIADIIYEIKD  480

Query  481  KKI  483
             KI
Sbjct  481  HKI  483

14) MYY_1872 in NC_017769


> NC_016808_R1|79|G72|378774001|YP_005176244.1|Pasteurella_multocida_36950|+|67348..68823|msr(E)|Pmu_03460|macrolide 
efflux 
protein
Length=491

 Score =  517 bits (1949),  Expect = 9e-148, Method: Compositional matrix adjust.
 Identities = 297/483 (62%), Positives = 407/483 (85%), Gaps = 0/483 (0%)

Query  1    MELILKAKDIRVEFKGRDVLDINELEVYDYDRIGLVGANGAGKSTLLRVLLGELTPPGCK  60
            M LI+KA++IR+++ GRDVLDI+ELE+  YDRIGLVG NGAGKS+LL+VL GE+  +   
Sbjct  1    MSLIIKARNIRLDYAGRDVLDIDELEIHSYDRIGLVGDNGAGKSSLLKVLNGEIVLAEAT  60

Query  61   MNRLGELAYIPQLDEVTLQEEKDFALVGKLGVEQLNIQTMSGGEETRLKIAQALSAQVHG  120
            ++R+G++A I+QL+ + ++   D A++++LGV +++ +TMSGGEETR KIA A+S QVHG
Sbjct  61   LQRFGDFAHISQLGGIEIETVEDRAMLSRLGVSNVQNDTMSGGEETRAKIAAAFSQQVHG  120

Query  121  ILADEPTSHLDREGIDFLIGQLKYFTGALLVISHDRYFLDEIVDKIWELKDGKITEYWGN  180
            ILADEPTSHLD +GID+LIGQLK F GALLVISHDRYFLD +VDKIWELKDGKITEYWG 
Sbjct  121  ILADEPTSHLDLNGIDLLIGQLKAFDGALLVISHDRYFLDMVVDKIWELKDGKITEYWGG  180

Query  181  YSDYLRQKEEERKSQAAEYEQFiaerarleraaeekrkqarkieqkakGSSKKKSTEDGG  240
            YSDYLRQKEEER+ QA EYE  + ER RLE A +EKR+QA ++++K KG   K+STE +G
Sbjct  181  YSDYLRQKEEERQHQAVEYELMMKERERLESAVQEKRQQANRLDNKKKGEKSKNSTESAG  240

Query  241  RLAHQKSIGSKEKKMYNAAKTLEHRIAALGKVEAPEGIRRIRFRQSKALELHNPYPIVGA  300
            RL+H K  G+K++K+Y+AAK++E R+AAL  ++APE +R IRFRQS ALELHN +PI + 
Sbjct  241  RLGHAKMTGTKQRKLYQAAKSMEKRLAALEDIQAPEHLRSIRFRQSSALELHNKFPITAD  300

Query  301  EINKVFGDKALFENASFQIPLGAKVALTGGNGIGKTTLIQMILNHEEGISISPKAKIGYF  360
             ++  FG +++F++A+F IPLGAKVA+TG+NG GKT+L++MI ++ +G++ISPKA IGYF
Sbjct  301  GLSLKFGSRTIFDDANFIIPLGAKVAITGSNGTGKTSLLKMISERADGLTISPKAEIGYF  360

Query  361  AQNGYKYNSNQNVMEFMQKDCDYNISEIRSVLASMGFKQNDIGKSLSVLSGGEIIKLLLA  420
            +Q GYK+N++++V+ FMQ +C+Y ++EIR+VLASMG+  NDI K+LS LSGGEIIKLLL+
Sbjct  361  TQTGYKFNTHKSVLSFMQEECEYTVAEIRAVLASMGIGANDIQKNLSDLSGGEIIKLLLS  420

Query  421  KMLMGRYNILIMDEPSNFLDIPSLEALEILMKEYTGTIVFITHDKRLLENVADVVYEIRD  480
            KML+G+YNIL+MDEP+N+LD+ S+ ALE +MK Y+GTI+F++HDK+L++N+AD++YEI+D
Sbjct  421  KMLLGKYNILLMDEPGNYLDLKSIAALETMMKSYAGTIIFVSHDKQLVDNIADIIYEIKD  480

Query  481  KKI  483
             KI
Sbjct  481  HKI  483

15) SPT_1925 in NC_012469


> NC_016808_R1|79|G72|378774001|YP_005176244.1|Pasteurella_multocida_36950|+|67348..68823|msr(E)|Pmu_03460|macrolide 
efflux 
protein
Length=491

 Score =  517 bits (1949),  Expect = 9e-148, Method: Compositional matrix adjust.
 Identities = 297/483 (62%), Positives = 407/483 (85%), Gaps = 0/483 (0%)

Query  1    MELILKAKDIRVEFKGRDVLDINELEVYDYDRIGLVGANGAGKSTLLRVLLGELTPPGCK  60
            M LI+KA++IR+++ GRDVLDI+ELE+  YDRIGLVG NGAGKS+LL+VL GE+  +   
Sbjct  1    MSLIIKARNIRLDYAGRDVLDIDELEIHSYDRIGLVGDNGAGKSSLLKVLNGEIVLAEAT  60

Query  61   MNRLGELAYIPQLDEVTLQEEKDFALVGKLGVEQLNIQTMSGGEETRLKIAQALSAQVHG  120
            ++R+G++A I+QL+ + ++   D A++++LGV +++ +TMSGGEETR KIA A+S QVHG
Sbjct  61   LQRFGDFAHISQLGGIEIETVEDRAMLSRLGVSNVQNDTMSGGEETRAKIAAAFSQQVHG  120

Query  121  ILADEPTSHLDREGIDFLIGQLKYFTGALLVISHDRYFLDEIVDKIWELKDGKITEYWGN  180
            ILADEPTSHLD +GID+LIGQLK F GALLVISHDRYFLD +VDKIWELKDGKITEYWG 
Sbjct  121  ILADEPTSHLDLNGIDLLIGQLKAFDGALLVISHDRYFLDMVVDKIWELKDGKITEYWGG  180

Query  181  YSDYLRQKEEERKSQAAEYEQFiaerarleraaeekrkqarkieqkakGSSKKKSTEDGG  240
            YSDYLRQKEEER+ QA EYE  + ER RLE A +EKR+QA ++++K KG   K+STE +G
Sbjct  181  YSDYLRQKEEERQHQAVEYELMMKERERLESAVQEKRQQANRLDNKKKGEKSKNSTESAG  240

Query  241  RLAHQKSIGSKEKKMYNAAKTLEHRIAALGKVEAPEGIRRIRFRQSKALELHNPYPIVGA  300
            RL+H K  G+K++K+Y+AAK++E R+AAL  ++APE +R IRFRQS ALELHN +PI + 
Sbjct  241  RLGHAKMTGTKQRKLYQAAKSMEKRLAALEDIQAPEHLRSIRFRQSSALELHNKFPITAD  300

Query  301  EINKVFGDKALFENASFQIPLGAKVALTGGNGIGKTTLIQMILNHEEGISISPKAKIGYF  360
             ++  FG +++F++A+F IPLGAKVA+TG+NG GKT+L++MI ++ +G++ISPKA IGYF
Sbjct  301  GLSLKFGSRTIFDDANFIIPLGAKVAITGSNGTGKTSLLKMISERADGLTISPKAEIGYF  360

Query  361  AQNGYKYNSNQNVMEFMQKDCDYNISEIRSVLASMGFKQNDIGKSLSVLSGGEIIKLLLA  420
            +Q GYK+N++++V+ FMQ +C+Y ++EIR+VLASMG+  NDI K+LS LSGGEIIKLLL+
Sbjct  361  TQTGYKFNTHKSVLSFMQEECEYTVAEIRAVLASMGIGANDIQKNLSDLSGGEIIKLLLS  420

Query  421  KMLMGRYNILIMDEPSNFLDIPSLEALEILMKEYTGTIVFITHDKRLLENVADVVYEIRD  480
            KML+G+YNIL+MDEP+N+LD+ S+ ALE +MK Y+GTI+F++HDK+L++N+AD++YEI+D
Sbjct  421  KMLLGKYNILLMDEPGNYLDLKSIAALETMMKSYAGTIIFVSHDKQLVDNIADIIYEIKD  480

Query  481  KKI  483
             KI
Sbjct  481  HKI  483

16) HMPREF0837_12213 in NC_014251


> NC_016808_R1|79|G72|378774001|YP_005176244.1|Pasteurella_multocida_36950|+|67348..68823|msr(E)|Pmu_03460|macrolide 
efflux 
protein
Length=491

 Score =  517 bits (1949),  Expect = 9e-148, Method: Compositional matrix adjust.
 Identities = 297/483 (62%), Positives = 407/483 (85%), Gaps = 0/483 (0%)

Query  1    MELILKAKDIRVEFKGRDVLDINELEVYDYDRIGLVGANGAGKSTLLRVLLGELTPPGCK  60
            M LI+KA++IR+++ GRDVLDI+ELE+  YDRIGLVG NGAGKS+LL+VL GE+  +   
Sbjct  1    MSLIIKARNIRLDYAGRDVLDIDELEIHSYDRIGLVGDNGAGKSSLLKVLNGEIVLAEAT  60

Query  61   MNRLGELAYIPQLDEVTLQEEKDFALVGKLGVEQLNIQTMSGGEETRLKIAQALSAQVHG  120
            ++R+G++A I+QL+ + ++   D A++++LGV +++ +TMSGGEETR KIA A+S QVHG
Sbjct  61   LQRFGDFAHISQLGGIEIETVEDRAMLSRLGVSNVQNDTMSGGEETRAKIAAAFSQQVHG  120

Query  121  ILADEPTSHLDREGIDFLIGQLKYFTGALLVISHDRYFLDEIVDKIWELKDGKITEYWGN  180
            ILADEPTSHLD +GID+LIGQLK F GALLVISHDRYFLD +VDKIWELKDGKITEYWG 
Sbjct  121  ILADEPTSHLDLNGIDLLIGQLKAFDGALLVISHDRYFLDMVVDKIWELKDGKITEYWGG  180

Query  181  YSDYLRQKEEERKSQAAEYEQFiaerarleraaeekrkqarkieqkakGSSKKKSTEDGG  240
            YSDYLRQKEEER+ QA EYE  + ER RLE A +EKR+QA ++++K KG   K+STE +G
Sbjct  181  YSDYLRQKEEERQHQAVEYELMMKERERLESAVQEKRQQANRLDNKKKGEKSKNSTESAG  240

Query  241  RLAHQKSIGSKEKKMYNAAKTLEHRIAALGKVEAPEGIRRIRFRQSKALELHNPYPIVGA  300
            RL+H K  G+K++K+Y+AAK++E R+AAL  ++APE +R IRFRQS ALELHN +PI + 
Sbjct  241  RLGHAKMTGTKQRKLYQAAKSMEKRLAALEDIQAPEHLRSIRFRQSSALELHNKFPITAD  300

Query  301  EINKVFGDKALFENASFQIPLGAKVALTGGNGIGKTTLIQMILNHEEGISISPKAKIGYF  360
             ++  FG +++F++A+F IPLGAKVA+TG+NG GKT+L++MI ++ +G++ISPKA IGYF
Sbjct  301  GLSLKFGSRTIFDDANFIIPLGAKVAITGSNGTGKTSLLKMISERADGLTISPKAEIGYF  360

Query  361  AQNGYKYNSNQNVMEFMQKDCDYNISEIRSVLASMGFKQNDIGKSLSVLSGGEIIKLLLA  420
            +Q GYK+N++++V+ FMQ +C+Y ++EIR+VLASMG+  NDI K+LS LSGGEIIKLLL+
Sbjct  361  TQTGYKFNTHKSVLSFMQEECEYTVAEIRAVLASMGIGANDIQKNLSDLSGGEIIKLLLS  420

Query  421  KMLMGRYNILIMDEPSNFLDIPSLEALEILMKEYTGTIVFITHDKRLLENVADVVYEIRD  480
            KML+G+YNIL+MDEP+N+LD+ S+ ALE +MK Y+GTI+F++HDK+L++N+AD++YEI+D
Sbjct  421  KMLLGKYNILLMDEPGNYLDLKSIAALETMMKSYAGTIIFVSHDKQLVDNIADIIYEIKD  480

Query  481  KKI  483
             KI
Sbjct  481  HKI  483

17) Dtox_2791 in NC_013216


> NC_016808_R1|79|G72|378774001|YP_005176244.1|Pasteurella_multocida_36950|+|67348..68823|msr(E)|Pmu_03460|macrolide 
efflux 
protein
Length=491

 Score =  512 bits (1932),  Expect = 2e-146, Method: Compositional matrix adjust.
 Identities = 295/485 (61%), Positives = 401/485 (83%), Gaps = 0/485 (0%)

Query  1    MELLIKAENVCVEYTGCDILNIDELELYDYDRIGLVGANGAGKSTLLKVLLGELTPPRCK  60
            M L+IKA N+ ++Y+G D+L+IDELE+  YDRIGLVG NGAGKS+LLKVL GE+  +   
Sbjct  1    MSLIIKARNIRLDYAGRDVLDIDELEIHSYDRIGLVGDNGAGKSSLLKVLNGEIVLAEAT  60

Query  61   VNRFGRFTYIPQLDEVTFQGIKDFALMGKLGVQQIKIQTMSGGEETRLKIAQALSEQVHG  120
            ++RFG F+ I+QL+ + ++ + D A++++LGV +++ +TMSGGEETR KIA A+S+QVHG
Sbjct  61   LQRFGDFAHISQLGGIEIETVEDRAMLSRLGVSNVQNDTMSGGEETRAKIAAAFSQQVHG  120

Query  121  IFADEPTCHLDHEGIDFLIGQLKFFSGALLIISHDRYFLDEVVDKIWELKNGKIIEYCGN  180
            I+ADEPT HLD +GID+LIGQLK F GALL+ISHDRYFLD VVDKIWELK+GKI EY G 
Sbjct  121  ILADEPTSHLDLNGIDLLIGQLKAFDGALLVISHDRYFLDMVVDKIWELKDGKITEYWGG  180

Query  181  YSGYLRQKEEKRQSQAARFEQFVaerdrleraaeekrkqarkIDQKAKGAAKINNSESRG  240
            YS+YLRQKEE RQ QA  +E  + ER+RLE A +EKR+QA ++D+K KG    N++ES G
Sbjct  181  YSDYLRQKEEERQHQAVEYELMMKERERLESAVQEKRQQANRLDNKKKGEKSKNSTESAG  240

Query  241  RLGHQKTMGSKQKTLYNAVKSMEHRIVALGDVEAPENIRTIRFRQSKALALHNPYPITAA  300
            RLGH K  G+KQ+ LY+A KSME R+ AL D++APE++R+IRFRQS AL LHN +PITA 
Sbjct  241  RLGHAKMTGTKQRKLYQAAKSMEKRLAALEDIQAPEHLRSIRFRQSSALELHNKFPITAD  300

Query  301  EISKRFGNKVLFEKASFNIPLGAKVALTGGNAAGKTTLFKMILNNEAGISISPKAVIGYF  360
             +S +FG++ +F+ A+F IPLGAKVA+TG+N++GKT+L+KMI +   G++ISPKA IGYF
Sbjct  301  GLSLKFGSRTIFDDANFIIPLGAKVAITGSNGTGKTSLLKMISERADGLTISPKAEIGYF  360

Query  361  DQNGYKYNRNQGIMEFMQENCDYQVPEIRSVMASLGFPENDIRKKLFVLSGGETIKLLLA  420
             Q GYK+N +++++ FMQE+C+Y V+EIR+V+AS+G+  NDI+K+L  LSGGE IKLLL+
Sbjct  361  TQTGYKFNTHKSVLSFMQEECEYTVAEIRAVLASMGIGANDIQKNLSDLSGGEIIKLLLS  420

Query  421  KMLLGRYNILLMDEPSNFLDLPSIEALEALMKNYEGTILFISHDKRLLENVADLVYEIQE  480
            KMLLG+YNILLMDEP+N+LDL SI ALE++MK+Y GTI+F+SHDK+L++N+AD++YEI++
Sbjct  421  KMLLGKYNILLMDEPGNYLDLKSIAALETMMKSYAGTIIFVSHDKQLVDNIADIIYEIKD  480

Query  481  GKIVQ  485
             KI++
Sbjct  481  HKIIK  485

18) Amet_1903 in NC_009633


> NC_016808_R1|79|G72|378774001|YP_005176244.1|Pasteurella_multocida_36950|+|67348..68823|msr(E)|Pmu_03460|macrolide 
efflux 
protein
Length=491

 Score =  511 bits (1927),  Expect = 5e-146, Method: Compositional matrix adjust.
 Identities = 303/485 (63%), Positives = 405/485 (84%), Gaps = 0/485 (0%)

Query  1    MTLLIKAKDICVEYLGRDILEIDELELYSYDRIGLVGANGAGKSTLLKVLLGELTPSGSK  60
            M+L+IKA++I ++Y GRD+L+IDELE+ SYDRIGLVG NGAGKS+LLKVL GE+  + + 
Sbjct  1    MSLIIKARNIRLDYAGRDVLDIDELEIHSYDRIGLVGDNGAGKSSLLKVLNGEIVLAEAT  60

Query  61   IKRLGKFAYISQLDEATLQKPKDFALMGKMGVDELDVEKMSGGEETRLKIAQALSEQVHG  120
            ++R+G FA ISQL+   ++   D A+++++GV +++ + MSGGEETR KIA A+S+QVHG
Sbjct  61   LQRFGDFAHISQLGGIEIETVEDRAMLSRLGVSNVQNDTMSGGEETRAKIAAAFSQQVHG  120

Query  121  IFADEPTSHLDREGIDFLIGQLKYFPGTLLVISHDRYFLDEVVDKIWELKDGKITEYWGN  180
            I+ADEPTSHLD +GID+LIGQLK F G+LLVISHDRYFLD VVDKIWELKDGKITEYWG 
Sbjct  121  ILADEPTSHLDLNGIDLLIGQLKAFDGALLVISHDRYFLDMVVDKIWELKDGKITEYWGG  180

Query  181  YSDYLHQKEEERKVQATKHEKFVAERERLEKSAEEKRKQAQKIVRKAKGAARKNSSESGG  240
            YSDYL+QKEEER+ QA   E  + ERERLE + +EKR+QA+++  K KG   KNS+ES+G
Sbjct  181  YSDYLRQKEEERQHQAVEYELMMKERERLESAVQEKRQQANRLDNKKKGEKSKNSTESAG  240

Query  241  RLGHQKTIGSKQKKMHNAAKSIEHKIEALGDVEAPENSQRIYFRQSAALELHNPYPIIVT  300
            RLGH K  G+KQ+K+ +AAKS+E ++ AL D++APE+ + I FRQS+ALELHN +PI   
Sbjct  241  RLGHAKMTGTKQRKLYQAAKSMEKRLAALEDIQAPEHLRSIRFRQSSALELHNKFPITAD  300

Query  301  EMTKRFGDKVLFEDASFNIPLGAKVALtggngtgkttLIKMILNREEGIDISPKAEIGYF  360
             ++ +FG + +F+DA+F IPLGAKVA+TG+NGTGKT+L+KMI +R +G+ ISPKAEIGYF
Sbjct  301  GLSLKFGSRTIFDDANFIIPLGAKVAITGSNGTGKTSLLKMISERADGLTISPKAEIGYF  360

Query  361  AQNAYKYNLNQNVMEFMQESCDYNVSEIRSVLASMGFKQNDISKKIAVLSGGEMIKLKLA  420
            +Q +YK+N +++V+ FMQE C+Y V+EIR+VLASMG+  NDI K+++ LSGGE+IKL L+
Sbjct  361  TQTGYKFNTHKSVLSFMQEECEYTVAEIRAVLASMGIGANDIQKNLSDLSGGEIIKLLLS  420

Query  421  QLLLGKYNILLMDEPGNYLDlmsleslemlmKKYAGTIIFISHDKRLVDNVANVVYEIKD  480
            ++LLGKYNILLMDEPGNYLDL S+ +LE +MK YAGTIIF+SHDK+LVDN+A+++YEIKD
Sbjct  421  KMLLGKYNILLMDEPGNYLDLKSIAALETMMKSYAGTIIFVSHDKQLVDNIADIIYEIKD  480

Query  481  QEIVQ  485
            + I++
Sbjct  481  HKIIK  485

19) SPPN_01640 in NC_015875


> NC_016808_R1|79|G72|378774001|YP_005176244.1|Pasteurella_multocida_36950|+|67348..68823|msr(E)|Pmu_03460|macrolide 
efflux 
protein
Length=491

 Score =  503 bits (1897),  Expect = 1e-143, Method: Compositional matrix adjust.
 Identities = 296/483 (62%), Positives = 406/483 (85%), Gaps = 0/483 (0%)

Query  1    MELILKAKDIRVEFKGRDVLDINELEVYDYDRIGLVGANGAGKSTLLRVLLGELTPPGCK  60
            M LI+KA++IR+++ GRDVLDI+ELE+  YDRIGLVG NGAGKS+LL+VL GE+  +   
Sbjct  1    MSLIIKARNIRLDYAGRDVLDIDELEIHSYDRIGLVGDNGAGKSSLLKVLNGEIVLAEAT  60

Query  61   MNRLGELAYIPQLDEVTLQEEKDFALVGKLGVEQLNIQTMSGGEETRLKIAQALSAQVHG  120
            ++R+G++A I+QL+ + ++   D A++++LGV +++ +TMSGGEETR KIA A+S QVHG
Sbjct  61   LQRFGDFAHISQLGGIEIETVEDRAMLSRLGVSNVQNDTMSGGEETRAKIAAAFSQQVHG  120

Query  121  ILADEPTSHLDREGIDFLIGQLKYFTGALLVISHDRYFLDEIVDKIWELKDGKITEYWGN  180
            ILADEPTSHLD +GID+LIGQLK F GALLVISHDRYFLD +VDKIWELKDGKITEYWG 
Sbjct  121  ILADEPTSHLDLNGIDLLIGQLKAFDGALLVISHDRYFLDMVVDKIWELKDGKITEYWGG  180

Query  181  YSDYLRQKEEERKSQAAEYEQFiaerarleraaeekrkqarkieqkakgsskkkstkdgg  240
            YSDYLRQKEEER+ QA EYE  + ER RLE A +EKR+QA ++++K KG   K+ST  +G
Sbjct  181  YSDYLRQKEEERQHQAVEYELMMKERERLESAVQEKRQQANRLDNKKKGEKSKNSTESAG  240

Query  241  RLAHQKSIGSKEKKMYNAAKTLEHRIAALGKVEAPEGIRRIRFRQSKALELHNPYPIVGA  300
            RL+H K  G+K++K+Y+AAK++E R+AAL  ++APE +R IRFRQS ALELHN +PI + 
Sbjct  241  RLGHAKMTGTKQRKLYQAAKSMEKRLAALEDIQAPEHLRSIRFRQSSALELHNKFPITAD  300

Query  301  EINKVFGDKALFENASFQIPLGAKVALTGGNGIGKTTLIQMILNHEEGISISPKAKIGYF  360
             ++  FG +++F++A+F IPLGAKVA+TG+NG GKT+L++MI ++ +G++ISPKA IGYF
Sbjct  301  GLSLKFGSRTIFDDANFIIPLGAKVAITGSNGTGKTSLLKMISERADGLTISPKAEIGYF  360

Query  361  AQNGYKYNSNQNVMEFMQKDCDYNISEIRSVLASMGFKQNDIGKSLSVLSGGEIIKLLLA  420
            +Q GYK+N++++V+ FMQ +C+Y ++EIR+VLASMG+  NDI K+LS LSGGEIIKLLL+
Sbjct  361  TQTGYKFNTHKSVLSFMQEECEYTVAEIRAVLASMGIGANDIQKNLSDLSGGEIIKLLLS  420

Query  421  KMLMGRYNILIMDEPSNFLDIPSLEALEILMKEYTGTIVFITHDKRLLENVADVVYEIRD  480
            KML+G+YNIL+MDEP+N+LD+ S+ ALE +MK Y+GTI+F++HDK+L++N+AD++YEI+D
Sbjct  421  KMLLGKYNILLMDEPGNYLDLKSIAALETMMKSYAGTIIFVSHDKQLVDNIADIIYEIKD  480

Query  481  KKI  483
             KI
Sbjct  481  HKI  483

20) SSUJS14_0633 in NC_017618


> NC_016808_R1|79|G72|378774001|YP_005176244.1|Pasteurella_multocida_36950|+|67348..68823|msr(E)|Pmu_03460|macrolide 
efflux 
protein
Length=491

 Score =  501 bits (1889),  Expect = 4e-143, Method: Compositional matrix adjust.
 Identities = 295/483 (62%), Positives = 410/483 (85%), Gaps = 0/483 (0%)

Query  1    MELILKAKDIRVEFKGHDVLDINELEVYDYDRIGLVGANGAGKSTLFKVLLGELIPPGCK  60
            M LI+KA++IR+++ G+DVLDI+ELE+  YDRIGLVG NGAGKS+L+KVL GE++ +   
Sbjct  1    MSLIIKARNIRLDYAGRDVLDIDELEIHSYDRIGLVGDNGAGKSSLLKVLNGEIVLAEAT  60

Query  61   MNHLGELAYIPQLDEVTLQEEKDFALVGKLGVEQLNIQTMSGGEETRLKIAQALSAQVHG  120
            ++++G++A I+QL+ + ++   D A++++LGV +++ +TMSGGEETR KIA A+S QVHG
Sbjct  61   LQRFGDFAHISQLGGIEIETVEDRAMLSRLGVSNVQNDTMSGGEETRAKIAAAFSQQVHG  120

Query  121  ILADEPTSHLDREGIDFLIGQLKYFTGALLVISHDRYFLDEIVDKIWELKDGKITEYWGN  180
            ILADEPTSHLD +GID+LIGQLK F GALLVISHDRYFLD +VDKIWELKDGKITEYWG 
Sbjct  121  ILADEPTSHLDLNGIDLLIGQLKAFDGALLVISHDRYFLDMVVDKIWELKDGKITEYWGG  180

Query  181  YSDYLRQKEEERKRQAAEYEQFiaerarleraaeekrkqarkieqkakgsskkksteggg  240
            YSDYLRQKEEER++QA EYE  + ER RLE A +EKR+QA ++++K KG   K+STE++G
Sbjct  181  YSDYLRQKEEERQHQAVEYELMMKERERLESAVQEKRQQANRLDNKKKGEKSKNSTESAG  240

Query  241  RLAHQKSIGSKEKKMYNAAKTLEHRIAALGKVEAPEGIRRIRFRQSKALELHNPYPIVGA  300
            RL+H K  G+K++K+Y+AAK++E R+AAL  ++APE +R IRFRQS ALELHN +PI + 
Sbjct  241  RLGHAKMTGTKQRKLYQAAKSMEKRLAALEDIQAPEHLRSIRFRQSSALELHNKFPITAD  300

Query  301  EINKVFGDKALFENASFQIPLGAKVALTGGNGIGKTTLIQMILNHEEGISISPKAKIGYF  360
             ++  FG +++F++A+F IPLGAKVA+TG+NG GKT+L++MI ++ +G++ISPKA IGYF
Sbjct  301  GLSLKFGSRTIFDDANFIIPLGAKVAITGSNGTGKTSLLKMISERADGLTISPKAEIGYF  360

Query  361  AQNGYKYNSNQNVMEFMQKDCDYNISEIRSVLASMGFKQNDIGKSLSVLSGGEIIKLLLA  420
            +Q GYK+N++++V+ FMQ +C+Y ++EIR+VLASMG+  NDI K+LS LSGGEIIKLLL+
Sbjct  361  TQTGYKFNTHKSVLSFMQEECEYTVAEIRAVLASMGIGANDIQKNLSDLSGGEIIKLLLS  420

Query  421  KMLMGRYNILIMDEPSNFLDIPSLEALEILMKEYTGTIVFITHDKRLLENVADVVYEIRD  480
            KML+G+YNIL+MDEP+N+LD+ S+ ALE +MK Y+GTI+F++HDK+L++N+AD++YEI+D
Sbjct  421  KMLLGKYNILLMDEPGNYLDLKSIAALETMMKSYAGTIIFVSHDKQLVDNIADIIYEIKD  480

Query  481  KKI  483
             KI
Sbjct  481  HKI  483

21) NJAUSS_0619 in NC_020526


> NC_016808_R1|79|G72|378774001|YP_005176244.1|Pasteurella_multocida_36950|+|67348..68823|msr(E)|Pmu_03460|macrolide 
efflux 
protein
Length=491

 Score =  501 bits (1889),  Expect = 4e-143, Method: Compositional matrix adjust.
 Identities = 295/483 (62%), Positives = 410/483 (85%), Gaps = 0/483 (0%)

Query  1    MELILKAKDIRVEFKGHDVLDINELEVYDYDRIGLVGANGAGKSTLFKVLLGELIPPGCK  60
            M LI+KA++IR+++ G+DVLDI+ELE+  YDRIGLVG NGAGKS+L+KVL GE++ +   
Sbjct  1    MSLIIKARNIRLDYAGRDVLDIDELEIHSYDRIGLVGDNGAGKSSLLKVLNGEIVLAEAT  60

Query  61   MNHLGELAYIPQLDEVTLQEEKDFALVGKLGVEQLNIQTMSGGEETRLKIAQALSAQVHG  120
            ++++G++A I+QL+ + ++   D A++++LGV +++ +TMSGGEETR KIA A+S QVHG
Sbjct  61   LQRFGDFAHISQLGGIEIETVEDRAMLSRLGVSNVQNDTMSGGEETRAKIAAAFSQQVHG  120

Query  121  ILADEPTSHLDREGIDFLIGQLKYFTGALLVISHDRYFLDEIVDKIWELKDGKITEYWGN  180
            ILADEPTSHLD +GID+LIGQLK F GALLVISHDRYFLD +VDKIWELKDGKITEYWG 
Sbjct  121  ILADEPTSHLDLNGIDLLIGQLKAFDGALLVISHDRYFLDMVVDKIWELKDGKITEYWGG  180

Query  181  YSDYLRQKEEERKRQAAEYEQFiaerarleraaeekrkqarkieqkakgsskkksteggg  240
            YSDYLRQKEEER++QA EYE  + ER RLE A +EKR+QA ++++K KG   K+STE++G
Sbjct  181  YSDYLRQKEEERQHQAVEYELMMKERERLESAVQEKRQQANRLDNKKKGEKSKNSTESAG  240

Query  241  RLAHQKSIGSKEKKMYNAAKTLEHRIAALGKVEAPEGIRRIRFRQSKALELHNPYPIVGA  300
            RL+H K  G+K++K+Y+AAK++E R+AAL  ++APE +R IRFRQS ALELHN +PI + 
Sbjct  241  RLGHAKMTGTKQRKLYQAAKSMEKRLAALEDIQAPEHLRSIRFRQSSALELHNKFPITAD  300

Query  301  EINKVFGDKALFENASFQIPLGAKVALTGGNGIGKTTLIQMILNHEEGISISPKAKIGYF  360
             ++  FG +++F++A+F IPLGAKVA+TG+NG GKT+L++MI ++ +G++ISPKA IGYF
Sbjct  301  GLSLKFGSRTIFDDANFIIPLGAKVAITGSNGTGKTSLLKMISERADGLTISPKAEIGYF  360

Query  361  AQNGYKYNSNQNVMEFMQKDCDYNISEIRSVLASMGFKQNDIGKSLSVLSGGEIIKLLLA  420
            +Q GYK+N++++V+ FMQ +C+Y ++EIR+VLASMG+  NDI K+LS LSGGEIIKLLL+
Sbjct  361  TQTGYKFNTHKSVLSFMQEECEYTVAEIRAVLASMGIGANDIQKNLSDLSGGEIIKLLLS  420

Query  421  KMLMGRYNILIMDEPSNFLDIPSLEALEILMKEYTGTIVFITHDKRLLENVADVVYEIRD  480
            KML+G+YNIL+MDEP+N+LD+ S+ ALE +MK Y+GTI+F++HDK+L++N+AD++YEI+D
Sbjct  421  KMLLGKYNILLMDEPGNYLDLKSIAALETMMKSYAGTIIFVSHDKQLVDNIADIIYEIKD  480

Query  481  KKI  483
             KI
Sbjct  481  HKI  483

22) SDSE_1551 in NC_019042


> NC_016808_R1|79|G72|378774001|YP_005176244.1|Pasteurella_multocida_36950|+|67348..68823|msr(E)|Pmu_03460|macrolide 
efflux 
protein
Length=491

 Score =  495 bits (1867),  Expect = 2e-141, Method: Compositional matrix adjust.
 Identities = 301/483 (63%), Positives = 406/483 (85%), Gaps = 0/483 (0%)

Query  1    MELILKAKDIRVEFTGRDVLDIDEIEVYDYDRIGLVGANGAGKSTLFKVLLGELTPPGCK  60
            M LI+KA++IR++++GRDVLDIDE+E+  YDRIGLVG NGAGKS+L+KVL GE+  +   
Sbjct  1    MSLIIKARNIRLDYAGRDVLDIDELEIHSYDRIGLVGDNGAGKSSLLKVLNGEIVLAEAT  60

Query  61   MNRLGELSFIPQLDEVSLREEKDFALVGKLGVEQLNIQTMSGGEETRLKIAQALSAQVHG  120
            ++R+G+++ I+QL+ + +    D A++++LGV +++ +TMSGGEETR KIA A+S QVHG
Sbjct  61   LQRFGDFAHISQLGGIEIETVEDRAMLSRLGVSNVQNDTMSGGEETRAKIAAAFSQQVHG  120

Query  121  ILADEPTSHLDREGIDFLIGQLKYFTGALLVISHDRYFLDEIVDKIWELKDGKITEYWGN  180
            ILADEPTSHLD +GID+LIGQLK F GALLVISHDRYFLD +VDKIWELKDGKITEYWG 
Sbjct  121  ILADEPTSHLDLNGIDLLIGQLKAFDGALLVISHDRYFLDMVVDKIWELKDGKITEYWGG  180

Query  181  YSDYLRQKEEERKSQAAQYEQFIaerarleraaeekrkqarklekkakGASRKKSTEGGG  240
            YSDYLRQKEEER+ QA +YE  + ER RLE A +EKR+QA +L++K KG   K+STE++G
Sbjct  181  YSDYLRQKEEERQHQAVEYELMMKERERLESAVQEKRQQANRLDNKKKGEKSKNSTESAG  240

Query  241  RLAHQKSMGSKEKKMHNVAKSLEHRIAALGNVEAPEDIRRIRFRQSKALELHNPYPIVGT  300
            RL+H K  G+K++K+ + AKS+E R+AAL +++APE++R IRFRQS ALELHN +PI + 
Sbjct  241  RLGHAKMTGTKQRKLYQAAKSMEKRLAALEDIQAPEHLRSIRFRQSSALELHNKFPITAD  300

Query  301  KINKIFGDKALFENASFQIPLGAKVALtggngtgkttLIQMILNHEDGITISRKAKIGYF  360
             ++  FG +++F++A+F IPLGAKVA+TG+NGTGKT+L++MI ++ DG+TIS KA IGYF
Sbjct  301  GLSLKFGSRTIFDDANFIIPLGAKVAITGSNGTGKTSLLKMISERADGLTISPKAEIGYF  360

Query  361  AQNGYKYNSKQKVLEFMQEDCDYNVSEIRSVLASIGIKQNDIGKSLAVLSGGEIMKLLLA  420
            +Q GYK+N+ + VL FMQE+C+Y V+EIR+VLAS+GI  NDI K+L+ LSGGEI+KLLL+
Sbjct  361  TQTGYKFNTHKSVLSFMQEECEYTVAEIRAVLASMGIGANDIQKNLSDLSGGEIIKLLLS  420

Query  421  KMLMGRYNILLMDEPSNFLDIPSLEALEILMKEYAGTIVFITHDKRLLDNVADVVYEISD  480
            KML+G+YNILLMDEP+N+LD+ S+ ALE +MK YAGTI+F++HDK+L+DN+AD++YEI D
Sbjct  421  KMLLGKYNILLMDEPGNYLDLKSIAALETMMKSYAGTIIFVSHDKQLVDNIADIIYEIKD  480

Query  481  KKI  483
             KI
Sbjct  481  HKI  483

23) Dhaf_0018 in NC_011830


> NC_016808_R1|79|G72|378774001|YP_005176244.1|Pasteurella_multocida_36950|+|67348..68823|msr(E)|Pmu_03460|macrolide 
efflux 
protein
Length=491

 Score =  491 bits (1851),  Expect = 5e-140, Method: Compositional matrix adjust.
 Identities = 298/483 (62%), Positives = 404/483 (84%), Gaps = 0/483 (0%)

Query  1    MELLLKATDIYVEYKGREILSINELELYNYDRIGLVGSNGAGKSTLLKVLLGELALPGCI  60
            M L++KA +I ++Y GR++L I+ELE+ +YDRIGLVG NGAGKS+LLKVL GE+ L+   
Sbjct  1    MSLIIKARNIRLDYAGRDVLDIDELEIHSYDRIGLVGDNGAGKSSLLKVLNGEIVLAEAT  60

Query  61   VNGIGNFAYIPQLTEAAWQESIDHALLGKLGVSGLDTQTMSGGEETRLKVAQALSGQVHG  120
            ++ +G+FA I+QL     +   D+A+L++LGVS ++ +TMSGGEETR K+A A+S QVHG
Sbjct  61   LQRFGDFAHISQLGGIEIETVEDRAMLSRLGVSNVQNDTMSGGEETRAKIAAAFSQQVHG  120

Query  121  IFADEPTSHLDREGIDFLIGQLQYFSGALLIISHDRYFLDKVVNKIWELKDGKITEYWGN  180
            I+ADEPTSHLD +GID+LIGQL+ F GALL+ISHDRYFLD VV+KIWELKDGKITEYWG 
Sbjct  121  ILADEPTSHLDLNGIDLLIGQLKAFDGALLVISHDRYFLDMVVDKIWELKDGKITEYWGG  180

Query  181  YSDYLGQKEEERQRQTAQYEQHVMerarleraaeekrkqaqkVDQKTKGAAKRGATESGG  240
            YSDYL QKEEERQ+Q+ +YE  + ER RLE A +EKR+QA+++D+K KG   + +TES+G
Sbjct  181  YSDYLRQKEEERQHQAVEYELMMKERERLESAVQEKRQQANRLDNKKKGEKSKNSTESAG  240

Query  241  RLGHQKTIGSKQKTLYKAAKSMEHRIESMGDISAPEKARTVRFRQSQALALHNPYPITGT  300
            RLGH K  G+KQ+ LY+AAKSME R+ ++ DI APE  R++RFRQS AL LHN +PIT+ 
Sbjct  241  RLGHAKMTGTKQRKLYQAAKSMEKRLAALEDIQAPEHLRSIRFRQSSALELHNKFPITAD  300

Query  301  EINKIFDNKVLFEKASFQIPLGAKVAFTGGNGTGKTTLFQMILHREAGIAISPKAEIGYF  360
             ++  F+++ +F+ A+F IPLGAKVA+TG+NGTGKT+L++MI +R  G++ISPKAEIGYF
Sbjct  301  GLSLKFGSRTIFDDANFIIPLGAKVAITGSNGTGKTSLLKMISERADGLTISPKAEIGYF  360

Query  361  AQNSYKFNRDQGVMTFMEDHCDYGQSEIRSVLASMGFSPNDIKKNLSVLSGGElikllla  420
            +Q +YKFN +++V++FM+++C+Y  +EIR+VLASMG+++NDI+KNLS LSGGE+IKLLL+
Sbjct  361  TQTGYKFNTHKSVLSFMQEECEYTVAEIRAVLASMGIGANDIQKNLSDLSGGEIIKLLLS  420

Query  421  kmllGRYNILLMDEPSNFLDLPGIEALEILMKSYAGTILFISHDQRLLENVADRIYAIKD  480
            KMLLG+YNILLMDEP+N+LDL +I ALE +MKSYAGTI+F+SHD++L++N+AD IY IKD
Sbjct  421  KMLLGKYNILLMDEPGNYLDLKSIAALETMMKSYAGTIIFVSHDKQLVDNIADIIYEIKD  480

Query  481  KRL  483
             ++
Sbjct  481  HKI  483

24) CKL_2618 in NC_009706


> NC_016808_R1|79|G72|378774001|YP_005176244.1|Pasteurella_multocida_36950|+|67348..68823|msr(E)|Pmu_03460|macrolide 
efflux 
protein
Length=491

 Score =  489 bits (1843),  Expect = 2e-139, Method: Compositional matrix adjust.
 Identities = 305/483 (64%), Positives = 406/483 (85%), Gaps = 0/483 (0%)

Query  1    MELILKAKDIRVEFKGRTCLDIDELEVYDYDRIGLVGANGAGKSTLLKVLLGELTPPGCK  60
            M LI+KA++IR+++ GR  LDIDELE+  YDRIGLVG NGAGKS+LLKVL GE+  +   
Sbjct  1    MSLIIKARNIRLDYAGRDVLDIDELEIHSYDRIGLVGDNGAGKSSLLKVLNGEIVLAEAT  60

Query  61   MNRLGELAYIPQLDEVTLQEEKDFALVGKLGVEQLDIQTMSGGEETRLKIAQALSAQVHG  120
            ++R+G++A I+QL+ + ++   D A++++LGV +++ +TMSGGEETR KIA A+S QVHG
Sbjct  61   LQRFGDFAHISQLGGIEIETVEDRAMLSRLGVSNVQNDTMSGGEETRAKIAAAFSQQVHG  120

Query  121  ILADEPTSHLDREGIDFLIGQLKYFTGALLVISHDRYFLDEVVDKIWELKDGKITEYWGN  180
            ILADEPTSHLD +GID+LIGQLK F GALLVISHDRYFLD VVDKIWELKDGKITEYWG 
Sbjct  121  ILADEPTSHLDLNGIDLLIGQLKAFDGALLVISHDRYFLDMVVDKIWELKDGKITEYWGG  180

Query  181  YSDYLRQKEEERKSQAAEYEQFVaerarleraaeekrkqarkigqkakgaskkkstkggg  240
            YSDYLRQKEEER+ QA EYE  + ER RLE A +EKR+QA ++++K KG   K+ST ++G
Sbjct  181  YSDYLRQKEEERQHQAVEYELMMKERERLESAVQEKRQQANRLDNKKKGEKSKNSTESAG  240

Query  241  RLAHQKSIGSKEKKMHNAAKSLEHRIAALGSVEAPEDIRRIRFRQSKALELHNPYPIVGK  300
            RL+H K  G+K++K+ +AAKS+E R+AAL  ++APE++R IRFRQS ALELHN +PI + 
Sbjct  241  RLGHAKMTGTKQRKLYQAAKSMEKRLAALEDIQAPEHLRSIRFRQSSALELHNKFPITAD  300

Query  301  EINKIFGDKVLFENASFQIPLGAKVALtggngtgkttLIQMILNHEDGISISPKAKIGYF  360
             ++  FG + +F++A+F IPLGAKVA+TG+NGTGKT+L++MI ++ DG++ISPKA IGYF
Sbjct  301  GLSLKFGSRTIFDDANFIIPLGAKVAITGSNGTGKTSLLKMISERADGLTISPKAEIGYF  360

Query  361  AQNGYKYNSNQKVLEFMQEDCDYNVSEIRSVLASMGFKQNDIRKSLSVLSGGEIMKLLLA  420
            +Q GYK+N+++ VL FMQE+C+Y V+EIR+VLASMG+  NDI+K+LS LSGGEI+KLLL+
Sbjct  361  TQTGYKFNTHKSVLSFMQEECEYTVAEIRAVLASMGIGANDIQKNLSDLSGGEIIKLLLS  420

Query  421  KMLMGRYNILLMDEPSNFLDIPSLEALEILMKEYAGTIVFITHDKRLLDNVADVIYEIKD  480
            KML+G+YNILLMDEP+N+LD+ S+ ALE +MK YAGTI+F++HDK+L+DN+AD+IYEIKD
Sbjct  421  KMLLGKYNILLMDEPGNYLDLKSIAALETMMKSYAGTIIFVSHDKQLVDNIADIIYEIKD  480

Query  481  KKL  483
             K+
Sbjct  481  HKI  483

25) CKR_2319 in NC_011837


> NC_016808_R1|79|G72|378774001|YP_005176244.1|Pasteurella_multocida_36950|+|67348..68823|msr(E)|Pmu_03460|macrolide 
efflux 
protein
Length=491

 Score =  489 bits (1842),  Expect = 2e-139, Method: Compositional matrix adjust.
 Identities = 305/483 (64%), Positives = 406/483 (85%), Gaps = 0/483 (0%)

Query  13   MELILKAKDIRVEFKGRTCLDIDELEVYDYDRIGLVGANGAGKSTLLKVLLGELTPPGCK  72
            M LI+KA++IR+++ GR  LDIDELE+  YDRIGLVG NGAGKS+LLKVL GE+  +   
Sbjct  1    MSLIIKARNIRLDYAGRDVLDIDELEIHSYDRIGLVGDNGAGKSSLLKVLNGEIVLAEAT  60

Query  73   MNRLGELAYIPQLDEVTLQEEKDFALVGKLGVEQLDIQTMSGGEETRLKIAQALSAQVHG  132
            ++R+G++A I+QL+ + ++   D A++++LGV +++ +TMSGGEETR KIA A+S QVHG
Sbjct  61   LQRFGDFAHISQLGGIEIETVEDRAMLSRLGVSNVQNDTMSGGEETRAKIAAAFSQQVHG  120

Query  133  ILADEPTSHLDREGIDFLIGQLKYFTGALLVISHDRYFLDEVVDKIWELKDGKITEYWGN  192
            ILADEPTSHLD +GID+LIGQLK F GALLVISHDRYFLD VVDKIWELKDGKITEYWG 
Sbjct  121  ILADEPTSHLDLNGIDLLIGQLKAFDGALLVISHDRYFLDMVVDKIWELKDGKITEYWGG  180

Query  193  YSDYLRQKEEERKSQAAEYEQFVaerarleraaeekrkqarkigqkakgaskkkstkggg  252
            YSDYLRQKEEER+ QA EYE  + ER RLE A +EKR+QA ++++K KG   K+ST ++G
Sbjct  181  YSDYLRQKEEERQHQAVEYELMMKERERLESAVQEKRQQANRLDNKKKGEKSKNSTESAG  240

Query  253  RLAHQKSIGSKEKKMHNAAKSLEHRIAALGSVEAPEDIRRIRFRQSKALELHNPYPIVGK  312
            RL+H K  G+K++K+ +AAKS+E R+AAL  ++APE++R IRFRQS ALELHN +PI + 
Sbjct  241  RLGHAKMTGTKQRKLYQAAKSMEKRLAALEDIQAPEHLRSIRFRQSSALELHNKFPITAD  300

Query  313  EINKIFGDKVLFENASFQIPLGAKVALtggngtgkttLIQMILNHEDGISISPKAKIGYF  372
             ++  FG + +F++A+F IPLGAKVA+TG+NGTGKT+L++MI ++ DG++ISPKA IGYF
Sbjct  301  GLSLKFGSRTIFDDANFIIPLGAKVAITGSNGTGKTSLLKMISERADGLTISPKAEIGYF  360

Query  373  AQNGYKYNSNQKVLEFMQEDCDYNVSEIRSVLASMGFKQNDIRKSLSVLSGGEIMKLLLA  432
            +Q GYK+N+++ VL FMQE+C+Y V+EIR+VLASMG+  NDI+K+LS LSGGEI+KLLL+
Sbjct  361  TQTGYKFNTHKSVLSFMQEECEYTVAEIRAVLASMGIGANDIQKNLSDLSGGEIIKLLLS  420

Query  433  KMLMGRYNILLMDEPSNFLDIPSLEALEILMKEYAGTIVFITHDKRLLDNVADVIYEIKD  492
            KML+G+YNILLMDEP+N+LD+ S+ ALE +MK YAGTI+F++HDK+L+DN+AD+IYEIKD
Sbjct  421  KMLLGKYNILLMDEPGNYLDLKSIAALETMMKSYAGTIIFVSHDKQLVDNIADIIYEIKD  480

Query  493  KKL  495
             K+
Sbjct  481  HKI  483

26) CKL_2537 in NC_009706


> NC_016808_R1|79|G72|378774001|YP_005176244.1|Pasteurella_multocida_36950|+|67348..68823|msr(E)|Pmu_03460|macrolide 
efflux 
protein
Length=491

 Score =  485 bits (1829),  Expect = 2e-138, Method: Compositional matrix adjust.
 Identities = 279/449 (63%), Positives = 370/449 (83%), Gaps = 0/449 (0%)

Query  1    MVGANGAGKSTLLKVLLRELTPPGCKINRFGGFAYIPQLDEVTLQGEKDFVLIGKLGVEQ  60
            +VG NGAGKS+LLKVL  E+  +   ++RFG+FA I+QL+ + ++   D  ++++LGV +
Sbjct  35   LVGDNGAGKSSLLKVLNGEIVLAEATLQRFGDFAHISQLGGIEIETVEDRAMLSRLGVSN  94

Query  61   LEVQTMSGGEETRLKIAQALSAQVHGLLADEPTSHLDREGIDFLIGQLKYFSGALLVISH  120
            ++ +TMSGGEETR KIA A+S QVHG+LADEPTSHLD +GID+LIGQLK F GALLVISH
Sbjct  95   VQNDTMSGGEETRAKIAAAFSQQVHGILADEPTSHLDLNGIDLLIGQLKAFDGALLVISH  154

Query  121  DRYFLDKVVDKIWELKDGKITEYWGNYSDYLRQKKEENKSQAAKYERFVAERDRLKQAAE  180
            DRYFLD VVDKIWELKDGKITEYWG YSDYLRQK EE + QA  YE  + ER+RL  A +
Sbjct  155  DRYFLDMVVDKIWELKDGKITEYWGGYSDYLRQKEEERQHQAVEYELMMKERERLESAVQ  214

Query  181  EKRKQARKIEQKAKGAGKKNNSESGGRLAHQKTMGSKQKTLYNAAKSMENRIAALGDVEA  240
            EKR+QA ++++K KG   KN++ES+GRL+H K  G+KQ+ LY+AAKSME+R+AAL D++A
Sbjct  215  EKRQQANRLDNKKKGEKSKNSTESAGRLGHAKMTGTKQRKLYQAAKSMEKRLAALEDIQA  274

Query  241  PEDICRIRFRQSKALELHNSHPIYGTEINKRFEDKILFEKASFSIPLGAKVALtggngtg  300
            PE++  IRFRQS ALELHN  PI +  ++ +F  + +F+ A+F IPLGAKVA+TG+NGTG
Sbjct  275  PEHLRSIRFRQSSALELHNKFPITADGLSLKFGSRTIFDDANFIIPLGAKVAITGSNGTG  334

Query  301  kttLIQMILKHEEGISISPKAEIGYFAQNGYKYNRNREVMEFMQEDCDYNVSEIRSVLLS  360
            KT+L++MI  + +G++ISPKAEIGYF+Q GYK+N ++ V+ FMQE+C+Y V+EIR+VL S
Sbjct  335  KTSLLKMISERADGLTISPKAEIGYFTQTGYKFNTHKSVLSFMQEECEYTVAEIRAVLAS  394

Query  361  MGFVQNDICKRLSILSGGEIIKLLLAKMLIGRYNILLMDEPSNFLDLSSLEALEMLMKGY  420
            MG+  NDI K LS LSGGEIIKLLL+KML+G+YNILLMDEP+N+LDL S+ ALE +MK+Y
Sbjct  395  MGIGANDIQKNLSDLSGGEIIKLLLSKMLLGKYNILLMDEPGNYLDLKSIAALETMMKSY  454

Query  421  AGTIVFITHDKRLIDNVADVVYEIKDKRL  449
            AGTI+F++HDK+L+DN+AD++YEIKD ++
Sbjct  455  AGTIIFVSHDKQLVDNIADIIYEIKDHKI  483

27) CKR_2248 in NC_011837


> NC_016808_R1|79|G72|378774001|YP_005176244.1|Pasteurella_multocida_36950|+|67348..68823|msr(E)|Pmu_03460|macrolide 
efflux 
protein
Length=491

 Score =  485 bits (1829),  Expect = 2e-138, Method: Compositional matrix adjust.
 Identities = 279/449 (63%), Positives = 370/449 (83%), Gaps = 0/449 (0%)

Query  1    MVGANGAGKSTLLKVLLRELTPPGCKINRFGGFAYIPQLDEVTLQGEKDFVLIGKLGVEQ  60
            +VG NGAGKS+LLKVL  E+  +   ++RFG+FA I+QL+ + ++   D  ++++LGV +
Sbjct  35   LVGDNGAGKSSLLKVLNGEIVLAEATLQRFGDFAHISQLGGIEIETVEDRAMLSRLGVSN  94

Query  61   LEVQTMSGGEETRLKIAQALSAQVHGLLADEPTSHLDREGIDFLIGQLKYFSGALLVISH  120
            ++ +TMSGGEETR KIA A+S QVHG+LADEPTSHLD +GID+LIGQLK F GALLVISH
Sbjct  95   VQNDTMSGGEETRAKIAAAFSQQVHGILADEPTSHLDLNGIDLLIGQLKAFDGALLVISH  154

Query  121  DRYFLDKVVDKIWELKDGKITEYWGNYSDYLRQKKEENKSQAAKYERFVAERDRLKQAAE  180
            DRYFLD VVDKIWELKDGKITEYWG YSDYLRQK EE + QA  YE  + ER+RL  A +
Sbjct  155  DRYFLDMVVDKIWELKDGKITEYWGGYSDYLRQKEEERQHQAVEYELMMKERERLESAVQ  214

Query  181  EKRKQARKIEQKAKGAGKKNNSESGGRLAHQKTMGSKQKTLYNAAKSMENRIAALGDVEA  240
            EKR+QA ++++K KG   KN++ES+GRL+H K  G+KQ+ LY+AAKSME+R+AAL D++A
Sbjct  215  EKRQQANRLDNKKKGEKSKNSTESAGRLGHAKMTGTKQRKLYQAAKSMEKRLAALEDIQA  274

Query  241  PEDICRIRFRQSKALELHNSHPIYGTEINKRFEDKILFEKASFSIPLGAKVALtggngtg  300
            PE++  IRFRQS ALELHN  PI +  ++ +F  + +F+ A+F IPLGAKVA+TG+NGTG
Sbjct  275  PEHLRSIRFRQSSALELHNKFPITADGLSLKFGSRTIFDDANFIIPLGAKVAITGSNGTG  334

Query  301  kttLIQMILKHEEGISISPKAEIGYFAQNGYKYNRNREVMEFMQEDCDYNVSEIRSVLLS  360
            KT+L++MI  + +G++ISPKAEIGYF+Q GYK+N ++ V+ FMQE+C+Y V+EIR+VL S
Sbjct  335  KTSLLKMISERADGLTISPKAEIGYFTQTGYKFNTHKSVLSFMQEECEYTVAEIRAVLAS  394

Query  361  MGFVQNDICKRLSILSGGEIIKLLLAKMLIGRYNILLMDEPSNFLDLSSLEALEMLMKGY  420
            MG+  NDI K LS LSGGEIIKLLL+KML+G+YNILLMDEP+N+LDL S+ ALE +MK+Y
Sbjct  395  MGIGANDIQKNLSDLSGGEIIKLLLSKMLLGKYNILLMDEPGNYLDLKSIAALETMMKSY  454

Query  421  AGTIVFITHDKRLIDNVADVVYEIKDKRL  449
            AGTI+F++HDK+L+DN+AD++YEIKD ++
Sbjct  455  AGTIIFVSHDKQLVDNIADIIYEIKDHKI  483

28) SPNINV200_08750 in NC_017593


> NC_016808_R1|79|G72|378774001|YP_005176244.1|Pasteurella_multocida_36950|+|67348..68823|msr(E)|Pmu_03460|macrolide 
efflux 
protein
Length=491

 Score =  481 bits (1814),  Expect = 4e-137, Method: Compositional matrix adjust.
 Identities = 295/483 (62%), Positives = 410/483 (85%), Gaps = 0/483 (0%)

Query  1    MELILKAKDISVEFKGHDVLDINELEVYDYDRIGLVGANGAGKSTLFKVLLGELIPPGCK  60
            M LI+KA++I +++ G+DVLDI+ELE+  YDRIGLVG NGAGKS+L+KVL GE++ +   
Sbjct  1    MSLIIKARNIRLDYAGRDVLDIDELEIHSYDRIGLVGDNGAGKSSLLKVLNGEIVLAEAT  60

Query  61   MNHLGELAYIPQLDEVTLQEEKDFALVGKLGVEQLNIQTMSGGEETRLKIAQALSAQVHG  120
            ++++G++A I+QL+ + ++   D A++++LGV +++ +TMSGGEETR KIA A+S QVHG
Sbjct  61   LQRFGDFAHISQLGGIEIETVEDRAMLSRLGVSNVQNDTMSGGEETRAKIAAAFSQQVHG  120

Query  121  ILADEPTSHLDREGIDFLIGQLKYFTGALLVISHDRYFLDEIVDKIWELKDGKITEYWGN  180
            ILADEPTSHLD +GID+LIGQLK F GALLVISHDRYFLD +VDKIWELKDGKITEYWG 
Sbjct  121  ILADEPTSHLDLNGIDLLIGQLKAFDGALLVISHDRYFLDMVVDKIWELKDGKITEYWGG  180

Query  181  YSDYLRQKEEERKRQAAEYEQFiaerarleraaeekrkqarkieqkakgsskkksteggg  240
            YSDYLRQKEEER++QA EYE  + ER RLE A +EKR+QA ++++K KG   K+STE++G
Sbjct  181  YSDYLRQKEEERQHQAVEYELMMKERERLESAVQEKRQQANRLDNKKKGEKSKNSTESAG  240

Query  241  RLAHQKSIGSKEKKMHNAAKSLENRIAALGKVEAPEGIRRIRFRQSKALELHNPYPIVGA  300
            RL+H K  G+K++K+ +AAKS+E+R+AAL  ++APE +R IRFRQS ALELHN +PI + 
Sbjct  241  RLGHAKMTGTKQRKLYQAAKSMEKRLAALEDIQAPEHLRSIRFRQSSALELHNKFPITAD  300

Query  301  EINKVFGDKALFENASFQIPLGAKVALtggngtgkttLIQMILNHEEGISISPKAKIGYF  360
             ++  FG +++F++A+F IPLGAKVA+TG+NGTGKT+L++MI ++ +G++ISPKA IGYF
Sbjct  301  GLSLKFGSRTIFDDANFIIPLGAKVAITGSNGTGKTSLLKMISERADGLTISPKAEIGYF  360

Query  361  AQNGYKYNSNQNVMEFMQKDCDYNISEIRSVLASMGFKQNDIGKSLSVLSGGEIIKLLLA  420
            +Q GYK+N++++V+ FMQ +C+Y ++EIR+VLASMG+  NDI K+LS LSGGEIIKLLL+
Sbjct  361  TQTGYKFNTHKSVLSFMQEECEYTVAEIRAVLASMGIGANDIQKNLSDLSGGEIIKLLLS  420

Query  421  KMLMGRYNILIMDEPSNFLDIPSLEALEILMKEYTGTIVFITHDKRLLENVADVVYEIRD  480
            KML+G+YNIL+MDEP+N+LD+ S+ ALE +MK Y+GTI+F++HDK+L++N+AD++YEI+D
Sbjct  421  KMLLGKYNILLMDEPGNYLDLKSIAALETMMKSYAGTIIFVSHDKQLVDNIADIIYEIKD  480

Query  481  KKI  483
             KI
Sbjct  481  HKI  483

29) M6_Spy1165 in NC_006086


> NC_016808_R1|79|G72|378774001|YP_005176244.1|Pasteurella_multocida_36950|+|67348..68823|msr(E)|Pmu_03460|macrolide 
efflux 
protein
Length=491

 Score =  481 bits (1814),  Expect = 4e-137, Method: Compositional matrix adjust.
 Identities = 295/483 (62%), Positives = 410/483 (85%), Gaps = 0/483 (0%)

Query  1    MELILKAKDISVEFKGHDVLDINELEVYDYDRIGLVGANGAGKSTLFKVLLGELIPPGCK  60
            M LI+KA++I +++ G+DVLDI+ELE+  YDRIGLVG NGAGKS+L+KVL GE++ +   
Sbjct  1    MSLIIKARNIRLDYAGRDVLDIDELEIHSYDRIGLVGDNGAGKSSLLKVLNGEIVLAEAT  60

Query  61   MNHLGELAYIPQLDEVTLQEEKDFALVGKLGVEQLNIQTMSGGEETRLKIAQALSAQVHG  120
            ++++G++A I+QL+ + ++   D A++++LGV +++ +TMSGGEETR KIA A+S QVHG
Sbjct  61   LQRFGDFAHISQLGGIEIETVEDRAMLSRLGVSNVQNDTMSGGEETRAKIAAAFSQQVHG  120

Query  121  ILADEPTSHLDREGIDFLIGQLKYFTGALLVISHDRYFLDEIVDKIWELKDGKITEYWGN  180
            ILADEPTSHLD +GID+LIGQLK F GALLVISHDRYFLD +VDKIWELKDGKITEYWG 
Sbjct  121  ILADEPTSHLDLNGIDLLIGQLKAFDGALLVISHDRYFLDMVVDKIWELKDGKITEYWGG  180

Query  181  YSDYLRQKEEERKRQAAEYEQFiaerarleraaeekrkqarkieqkakgsskkksteggg  240
            YSDYLRQKEEER++QA EYE  + ER RLE A +EKR+QA ++++K KG   K+STE++G
Sbjct  181  YSDYLRQKEEERQHQAVEYELMMKERERLESAVQEKRQQANRLDNKKKGEKSKNSTESAG  240

Query  241  RLAHQKSIGSKEKKMHNAAKSLENRIAALGKVEAPEGIRRIRFRQSKALELHNPYPIVGA  300
            RL+H K  G+K++K+ +AAKS+E+R+AAL  ++APE +R IRFRQS ALELHN +PI + 
Sbjct  241  RLGHAKMTGTKQRKLYQAAKSMEKRLAALEDIQAPEHLRSIRFRQSSALELHNKFPITAD  300

Query  301  EINKVFGDKALFENASFQIPLGAKVALtggngtgkttLIQMILNHEEGISISPKAKIGYF  360
             ++  FG +++F++A+F IPLGAKVA+TG+NGTGKT+L++MI ++ +G++ISPKA IGYF
Sbjct  301  GLSLKFGSRTIFDDANFIIPLGAKVAITGSNGTGKTSLLKMISERADGLTISPKAEIGYF  360

Query  361  AQNGYKYNSNQNVMEFMQKDCDYNISEIRSVLASMGFKQNDIGKSLSVLSGGEIIKLLLA  420
            +Q GYK+N++++V+ FMQ +C+Y ++EIR+VLASMG+  NDI K+LS LSGGEIIKLLL+
Sbjct  361  TQTGYKFNTHKSVLSFMQEECEYTVAEIRAVLASMGIGANDIQKNLSDLSGGEIIKLLLS  420

Query  421  KMLMGRYNILIMDEPSNFLDIPSLEALEILMKEYTGTIVFITHDKRLLENVADVVYEIRD  480
            KML+G+YNIL+MDEP+N+LD+ S+ ALE +MK Y+GTI+F++HDK+L++N+AD++YEI+D
Sbjct  421  KMLLGKYNILLMDEPGNYLDLKSIAALETMMKSYAGTIIFVSHDKQLVDNIADIIYEIKD  480

Query  481  KKI  483
             KI
Sbjct  481  HKI  483

30) Clo1100_1986 in NC_016791


> NC_016808_R1|79|G72|378774001|YP_005176244.1|Pasteurella_multocida_36950|+|67348..68823|msr(E)|Pmu_03460|macrolide 
efflux 
protein
Length=491

 Score =  476 bits (1796),  Expect = 1e-135, Method: Compositional matrix adjust.
 Identities = 296/483 (62%), Positives = 396/483 (82%), Gaps = 0/483 (0%)

Query  1    MELIIKAKDIRLEYTGRdvldidelelydydRIGLVGANGAGKSTLLKVLLGELTPLGCK  60
            M LIIKA++IRL+Y+GRDVLDIDELE+  YDRIGLVG NGAGKS+LLKVL GE+      
Sbjct  1    MSLIIKARNIRLDYAGRDVLDIDELEIHSYDRIGLVGDNGAGKSSLLKVLNGEIVLAEAT  60

Query  61   ISRRGGFAYIPQLDEVTLQEEKDFTLIGKLSVGQLEVKTMSGGEETRLKIAQALSAQVHC  120
            + R G+FA I+QL+ + ++   D +++++L+V++++  TMSGGEETR KIA A+S QVH 
Sbjct  61   LQRFGDFAHISQLGGIEIETVEDRAMLSRLGVSNVQNDTMSGGEETRAKIAAAFSQQVHG  120

Query  121  LLADEPTSHLDREGTDFLIGQLKYFSGALLVISHDRYFLDEVADKIWELEDGKITEYWGN  180
            +LADEPTSHLD +G D+LIGQLK F GALLVISHDRYFLD V DKIWEL DGKITEYWG 
Sbjct  121  ILADEPTSHLDLNGIDLLIGQLKAFDGALLVISHDRYFLDMVVDKIWELKDGKITEYWGG  180

Query  181  YSYYLCQKENERKNQVAKYDQFIAERDRLEqaakdkrkqarkIEQKAKDVAKKKTSERGG  240
            YS YL QKE+ER++Q   Y+  + ER+RLE A ++KR+QA ++++K K+   K+++E +G
Sbjct  181  YSDYLRQKEEERQHQAVEYELMMKERERLESAVQEKRQQANRLDNKKKGEKSKNSTESAG  240

Query  241  RLAHQKTMGSKQKTLYKAAKSLEHRKAALGDIKAPESIRTIRFRQGKVLELHNPYPIIGT  300
            RL+H K  G+KQ+ LY+AAKS+E R AAL DI+APE +R+IRFRQ+  LELHN +PI + 
Sbjct  241  RLGHAKMTGTKQRKLYQAAKSMEKRLAALEDIQAPEHLRSIRFRQSSALELHNKFPITAD  300

Query  301  EINKRFGDKGLFENASFSIPLGAKVALtggngtgkttLIEMILNHEKGISISSKAEIGYF  360
             ++ +FG + +F++A+F IPLGAKVA+TG+NGTGKT+L+ MI ++  G++IS+KAEIGYF
Sbjct  301  GLSLKFGSRTIFDDANFIIPLGAKVAITGSNGTGKTSLLKMISERADGLTISPKAEIGYF  360

Query  361  AQNGYKYNPNQFVMEFMQEDCDYNVSEIRSVLASMSFVQNDIGKRLSVLSGGEISKLLLA  420
            +Q GYK+N ++ V+ FMQE+C+Y V+EIR+VLASM++  NDI K LS LSGGEI KLLL+
Sbjct  361  TQTGYKFNTHKSVLSFMQEECEYTVAEIRAVLASMGIGANDIQKNLSDLSGGEIIKLLLS  420

Query  421  KMLMGRYNILLMDEPSNFLDLPSLEALEVLMKGYAGTIVFITHDKRLLDNVADIIYEIKD  480
            KML+G+YNILLMDEP+N+LDL S+ ALE +MK+YAGTI+F++HDK+L+DN+ADIIYEIKD
Sbjct  421  KMLLGKYNILLMDEPGNYLDLKSIAALETMMKSYAGTIIFVSHDKQLVDNIADIIYEIKD  480

Query  481  KKL  483
             K+
Sbjct  481  HKI  483

31) Closa_1123 in NC_014376


> NC_016808_R1|79|G72|378774001|YP_005176244.1|Pasteurella_multocida_36950|+|67348..68823|msr(E)|Pmu_03460|macrolide 
efflux 
protein
Length=491

 Score =  458 bits (1724),  Expect = 4e-130, Method: Compositional matrix adjust.
 Identities = 274/448 (62%), Positives = 372/448 (84%), Gaps = 0/448 (0%)

Query  1    MELLLKVKDIRVEYAGRSVldidelelydydRIGLVGKNGSGKSTLLKILSGELALPKIQ  60
            M L++K ++IR++YAGR VLDIDELE+  YDRIGLVG NG+GKS+LLK+L+GE+ L+   
Sbjct  1    MSLIIKARNIRLDYAGRDVLDIDELEIHSYDRIGLVGDNGAGKSSLLKVLNGEIVLAEAT  60

Query  61   IAKNGTFSLIPQMDDVIVKDGKDYFLMGKLNVDRLEMQTMSGGEETRLKIVQALSEHVHG  120
            + + G F+ I+Q++++ +    D  ++++L V  ++ +TMSGGEETR KI  A+S++VHG
Sbjct  61   LQRFGDFAHISQLGGIEIETVEDRAMLSRLGVSNVQNDTMSGGEETRAKIAAAFSQQVHG  120

Query  121  IFADEPTSHLDQEGINFLIGQFKSFPGALLVISHDRYFLDAVIDKIWELKDGKITEYWGN  180
            I+ADEPTSHLD +GI++LIGQ+K+F GALLVISHDRYFLD V+DKIWELKDGKITEYWG 
Sbjct  121  ILADEPTSHLDLNGIDLLIGQLKAFDGALLVISHDRYFLDMVVDKIWELKDGKITEYWGG  180

Query  181  YSDYVNQKEEERKQQISQYEHFIAERDRLERAVSEkqkqaqkidqkakgakkkNSSESGG  240
            YSDY+ QKEEER++Q  +YE  + ER+RLE AV EK++QA+++D+K KG K KNS+ES+G
Sbjct  181  YSDYLRQKEEERQHQAVEYELMMKERERLESAVQEKRQQANRLDNKKKGEKSKNSTESAG  240

Query  241  RLSHQETTGSKQKKLYNAAKNMEHRISALGDIQMPEAVRTVRFRQSKALELHNPYPITGT  300
            RL+H   TG+KQ+KLY+AAK+ME R++AL DIQ PE +R++RFRQS ALELHN +PIT+ 
Sbjct  241  RLGHAKMTGTKQRKLYQAAKSMEKRLAALEDIQAPEHLRSIRFRQSSALELHNKFPITAD  300

Query  301  DICKHFDDKVLFDNASFQIPLGTKVALIGGNGTGKTTLFQMIMNREKGIVISPKAKIGFF  360
            ++   F+ + +FD+A+F IPLG+KVA+ G+NGTGKT+L++MI +R  G+ ISPKA IG+F
Sbjct  301  GLSLKFGSRTIFDDANFIIPLGAKVAITGSNGTGKTSLLKMISERADGLTISPKAEIGYF  360

Query  361  SQTGYKFNRKQRLIEFMQEDCDYQVSEIRSVLASMGFLQNDITKELSFLSGGEIIKVLLT  420
            +QTGYKFN  + ++ FMQE+C+Y V+EIR+VLASMG+  NDI K+LS LSGGEIIK+LL+
Sbjct  361  TQTGYKFNTHKSVLSFMQEECEYTVAEIRAVLASMGIGANDIQKNLSDLSGGEIIKLLLS  420

Query  421  KMLLGRYNILLMDEPSNFLDLPAVEALE  448
            KMLLG+YNILLMDEP+N+LDL ++ ALE
Sbjct  421  KMLLGKYNILLMDEPGNYLDLKSIAALE  448


 Score = 47.9 bits (162),  Expect = 1e-06, Method: Compositional matrix adjust.
 Identities = 44/187 (24%), Positives = 109/187 (59%), Gaps = 17/187 (9%)

Query  5    LKVKDIRVEYAGRSVldidelelydydRIGLVGKNGSGKSTLLKILS---GELAL-PKIQ  60
            +   ++ + +++R+++D  ++ +    ++++ G NG+GK++LLK++S   + L++ PK +
Sbjct  297  ITADGLSLKFGSRTIFDDANFIIPLGAKVAITGSNGTGKTSLLKMISERADGLTISPKAE  356

Query  61   IA--KNGTFSLIPQMDDV-IVKDGKDYFL------MGKLNVDRLEMQT----MSGGEETR  107
            I+   +  + +  +   + ++++  +Y +      ++ + ++  ++Q     +SGGE  +
Sbjct  357  IGYFTQTGYKFNTHKSVLSFMQEECEYTVAEIRAVLASMGIGANDIQKNLSDLSGGEIIK  416

Query  108  LKIVQALSEHVHGIFADEPTSHLDQEGINFLIGQFKSFPGALLVISHDRYFLDAVIDKIW  167
            L + + L    + ++ DEP + LD  +I  L    KS++G+++ +SHD+ ++D + D I 
Sbjct  417  LLLSKMLLGKYNILLMDEPGNYLDLKSIAALETMMKSYAGTIIFVSHDKQLVDNIADIIY  476

Query  168  ELKDGKI  174
            E+KD KI
Sbjct  477  EIKDHKI  483

32) DSY0081 in NC_007907


> NC_016808_R1|79|G72|378774001|YP_005176244.1|Pasteurella_multocida_36950|+|67348..68823|msr(E)|Pmu_03460|macrolide 
efflux 
protein
Length=491

 Score =  411 bits (1545),  Expect = 7e-116, Method: Compositional matrix adjust.
 Identities = 249/412 (61%), Positives = 339/412 (83%), Gaps = 0/412 (0%)

Query  68   MELLLKATDIYVEYKGREILSINELELYNYDRIGLVGSNGAGKSTLIKVLLGELALPGCI  127
            M L++KA +I ++Y GR++L I+ELE+ +YDRIGLVG NGAGKS+L+KVL GE+ L+   
Sbjct  1    MSLIIKARNIRLDYAGRDVLDIDELEIHSYDRIGLVGDNGAGKSSLLKVLNGEIVLAEAT  60

Query  128  VKGIGNFAYIPQLTEAAWQESIDHALLGKLGVSRLDTQTMSGGEETRLKVAQALSGQVHG  187
            ++ +G+FA I+QL     +   D+A+L++LGVS ++ +TMSGGEETR K+A A+S QVHG
Sbjct  61   LQRFGDFAHISQLGGIEIETVEDRAMLSRLGVSNVQNDTMSGGEETRAKIAAAFSQQVHG  120

Query  188  IFADEPTSHLDREGIDFLIGQLQYFSGALLIISHDRYFLDKVVNKIWELKDGKITEYWGN  247
            I+ADEPTSHLD +GID+LIGQL+ F GALL+ISHDRYFLD VV+KIWELKDGKITEYWG 
Sbjct  121  ILADEPTSHLDLNGIDLLIGQLKAFDGALLVISHDRYFLDMVVDKIWELKDGKITEYWGG  180

Query  248  YSDYLGQKEEERQRQTAQYEQHVMerarleraaeekrkqaqkVDQktkgaakkgatESGG  307
            YSDYL QKEEERQ+Q+ +YE  + ER RLE A +EKR+QA+++D+K KG   K +TES+G
Sbjct  181  YSDYLRQKEEERQHQAVEYELMMKERERLESAVQEKRQQANRLDNKKKGEKSKNSTESAG  240

Query  308  RLGHQKTIGSKQKTLYKAAKSMEHRIESMGDISAPEKARTVRFRQSQALALHNPYPITGT  367
            RLGH K  G+KQ+ LY+AAKSME R+ ++ DI APE  R++RFRQS AL LHN +PIT+ 
Sbjct  241  RLGHAKMTGTKQRKLYQAAKSMEKRLAALEDIQAPEHLRSIRFRQSSALELHNKFPITAD  300

Query  368  EINKIFDNKVLFEKASFQIPLGAKVAFTGGNGTGKTTLFQMILHREAGIAISPKAEIGYF  427
             ++  F+++ +F+ A+F IPLGAKVA+TG+NGTGKT+L++MI +R  G++ISPKAEIGYF
Sbjct  301  GLSLKFGSRTIFDDANFIIPLGAKVAITGSNGTGKTSLLKMISERADGLTISPKAEIGYF  360

Query  428  AQNSYKFNRDQGVMTFMEDHCDYGQSEIRSVLASMGFSPNDIKKNLSVLSGG  479
            +Q +YKFN +++V++FM+++C+Y  +EIR+VLASMG+++NDI+KNLS LSGG
Sbjct  361  TQTGYKFNTHKSVLSFMQEECEYTVAEIRAVLASMGIGANDIQKNLSDLSGG  412


 Score = 45.6 bits (153),  Expect = 8e-06, Method: Compositional matrix adjust.
 Identities = 44/162 (28%), Positives = 95/162 (59%), Gaps = 21/162 (12%)

Query  99   RIGLVGSNGAGKSTLIKVLLGELALPGCIVKGIGNFAYIPQLT---------------EA  143
            ++++ GSNG+GK++L+K +++E A  G  +   ++++Y+ Q                 E 
Sbjct  324  KVAITGSNGTGKTSLLK-MISERA-DGLTISPKAEIGYFTQTGYKFNTHKSVLSFMQEEC  381

Query  144  AWQESIDHALLGKLGVSRLDTQT----MSGGEETRLKVAQALSGQVHGIFADEPTSHLDR  199
                +  +A+L+ +G++  D Q     +SGGE  +L +++ L G+ + ++ DEP + LD 
Sbjct  382  EYTVAEIRAVLASMGIGANDIQKNLSDLSGGEIIKLLLSKMLLGKYNILLMDEPGNYLDL  441

Query  200  EGIDFLIGQLQYFSGALLIISHDRYFLDKVVNKIWELKDGKI  241
             +I  L   ++ ++G+++++SHD+ ++D++ + I E+KD KI
Sbjct  442  KSIAALETMMKSYAGTIIFVSHDKQLVDNIADIIYEIKDHKI  483

33) msrA in NC_010382


> NC_016808_R1|79|G72|378774001|YP_005176244.1|Pasteurella_multocida_36950|+|67348..68823|msr(E)|Pmu_03460|macrolide 
efflux 
protein
Length=491

 Score =  357 bits (1341),  Expect = 9e-100, Method: Compositional matrix adjust.
 Identities = 201/474 (43%), Positives = 348/474 (74%), Gaps = 5/474 (1%)

Query  13   VSYLDKEILNIEKLAIHQFDRIGIVGKNGAGKSTLMKILASKIQPTSGIVKSHVHFGYFE  72
            + Y ++++L+I+ L IH +DRIG+VG NGAGKS+L+K+L + I  + + ++   +F+ + 
Sbjct  12   LDYAGRDVLDIDELEIHSYDRIGLVGDNGAGKSSLLKVLNGEIVLAEATLQRFGDFAHIS  71

Query  73   QMEAPMLVEAEGQ-LLGKLAIPS-NSEGLSGGEQTRLKLAQLFSYYKEALLIDEPTTHLD  130
            Q+ +  +   E++ +L++L++++ +++ +SGGE+TR K+A  FS   +++L DEPT+HLD
Sbjct  72   QLGGIEIETVEDRAMLSRLGVSNVQNDTMSGGEETRAKIAAAFSQQVHGILADEPTSHLD  131

Query  131  QEGISFLVDELRYYYGALVLISHDRAVLDELVTTIWEIDGGTVNIYSGNYSNYAWQKQLE  190
             +GI +L+++L+ + GAL++ISHDR  LD +V  IWE+ +G +  Y G YS+Y +QK+ E
Sbjct  132  LNGIDLLIGQLKAFDGALLVISHDRYFLDMVVDKIWELKDGKITEYWGGYSDYLRQKEEE  191

Query  191  RDQQRQAHDLYLKERSRLEKSAEDKMKKAEKITQA--GNMSKREAHAKPNLTFMTKSKGT  248
            R++Q    +L +KER RLE + ++K ++A+++ +   G+ SK  +++   L   +K  GT
Sbjct  192  RQHQAVEYELMMKERERLESAVQEKRQQANRLDNKKKGEKSKNSTESAGRLGH-AKMTGT  250

Query  249  SQKNVQRAAKAIEQRIEKLQKVDAVQVDRKIVFRQSKALELHNKFPIMADQFTLHVPGKA  308
             Q+++ +AAK++E+R+  L+ ++A +  R I FRQS ALELHNKFPI AD ++L   +++
Sbjct  251  KQRKLYQAAKSMEKRLAALEDIQAPEHLRSIRFRQSSALELHNKFPITADGLSLKFGSRT  310

Query  309  LLEEVNFQIPLGKKIVLTGSNGCGKSTLLRYIATNGEGLTISPKAKVGYFNQMSYQFKSE  368
            ++++ NF IPLG K+ +TGSNG GK++LL+ I+  ++GLTISPKA +GYF Q +Y+F+++
Sbjct  311  IFDDANFIIPLGAKVAITGSNGTGKTSLLKMISERADGLTISPKAEIGYFTQTGYKFNTH  370

Query  369  ETVLQFLKNRADYDEGFLRNILSSMQFVGTDIQKSVNSLSGGEAIRLQLCYLFLGNYNIL  428
             +VL F+++  +Y  + +R +L+SM + + DIQK+++ LSGGE I+L L  ++LG+YNIL
Sbjct  371  KSVLSFMQEECEYTVAEIRAVLASMGIGANDIQKNLSDLSGGEIIKLLLSKMLLGKYNIL  430

Query  429  LLDEPTNFLDIQALEALEQFITAYEGTVIFVTHDKNFIENVADIHLTIKNNKIF  482
            L+DEP N+LD++++ ALE  + +Y GT+IFV+HDK++++N+ADI   IK++KI+
Sbjct  431  LMDEPGNYLDLKSIAALETMMKSYAGTIIFVSHDKQLVDNIADIIYEIKDHKII  484


 Score = 55.5 bits (191),  Expect = 7e-09, Method: Compositional matrix adjust.
 Identities = 48/182 (27%), Positives = 102/182 (57%), Gaps = 25/182 (13%)

Query  9    DRLIVSYLDKEILNIEKLAIHQFDRIGIVGKNGAGKSTLMKILASKIQPTSGIVKSHVHF  68
            D L + +  + I++  ++ I    +++I G NG+GK++L+K+++ + +  +  + +  ++
Sbjct  300  DGLSLKFGSRTIFDDANFIIPLGAKVAITGSNGTGKTSLLKMISERADGLT--ISPKAEI  357

Query  69   GYFEQ------MEAPML----------VEAEGQLLGKLAIPSNS-----EGLSGGEQTRL  107
            GYF Q       + ++L          V     +L+ ++I +N       +LSGGE  +L
Sbjct  358  GYFTQTGYKFNTHKSVLSFMQEECEYTVAEIRAVLASMGIGANDIQKNLSDLSGGEIIKL  417

Query  108  KLAQ-LFSYYKEALLIDEPTTHLDQEGISFLVDELRYYYGALVLISHDRAVLDELVTTIW  166
             L++ L++ Y + LL+DEP   LD  +I+ L   ++ Y G+++++SHD+ ++D++   I 
Sbjct  418  LLSKMLLGKY-NILLMDEPGNYLDLKSIAALETMMKSYAGTIIFVSHDKQLVDNIADIIY  476

Query  167  EI  168
            EI
Sbjct  477  EI  478


 Score = 51.3 bits (175),  Expect = 1e-07, Method: Compositional matrix adjust.
 Identities = 51/187 (28%), Positives = 109/187 (59%), Gaps = 17/187 (9%)

Query  295  IMADQFTLHVPGKALLEEVNFQIPLGKKIVLTGSNGCGKSTLLRYIATNGEGLTISPKAK  354
            I A ++ L+ +G+ +L+  +++I    +I L G NG GKS+LL+ +      L+ +   +
Sbjct  5    IKARNIRLDYAGRDVLDIDELEIHSYDRIGLVGDNGAGKSSLLK-VLNGEIVLAEATLQR  63

Query  355  VGYFNQMSYQFKSEETVLQFLKNRADYDEGFLRNILSSMQFVGTDIQKSVNSLSGGEAIR  414
             G F ++S Q+ + E  ++ + +RA         +LS +    +++Q+  +++SGGE  R
Sbjct  64   FGDFAHIS-QLGGIE--IETVEDRA---------MLSRLGV--SNVQN--DTMSGGEETR  107

Query  415  LQLCYLFLGNYNILLLDEPTNFLDIQALEALEQFITAYEGTVIFVTHDKNFIENVADIHL  474
             ++   F  + + +L DEPT+ LD+++++ L   + A++G+++ ++HD+ F++ V D   
Sbjct  108  AKIAAAFSQQVHGILADEPTSHLDLNGIDLLIGQLKAFDGALLVISHDRYFLDMVVDKIW  167

Query  475  TIKNNKI  481
             +K+ KI
Sbjct  168  ELKDGKI  174

34) B1NLA3E_11850 in NC_021171


> NC_016808_R1|79|G72|378774001|YP_005176244.1|Pasteurella_multocida_36950|+|67348..68823|msr(E)|Pmu_03460|macrolide 
efflux 
protein
Length=491

 Score =  340 bits (1277),  Expect = 1e-94, Method: Compositional matrix adjust.
 Identities = 203/475 (43%), Positives = 347/475 (74%), Gaps = 1/475 (0%)

Query  10   NIELSFLDKLILYIQRLSVYQFDRIGFVGKNGVGKSTLLKLMNGQILPDKGHVNRFVDFA  69
            NI L + ++ +L I+ L +  +DRIG+VG NG GKS+LLK++NG+I+   + ++RF DFA
Sbjct  9    NIRLDYAGRDVLDIDELEIHSYDRIGLVGDNGAGKSSLLKVLNGEIVLAEATLQRFGDFA  68

Query  70   YFDQLKT-PVEKDVDYELLGKLAIPQTEIENFSGGEQTRMKLAELFSTYHEGLLIDEPTT  128
             + QL    +E   D  +L++L++++ + +  SGGE+TR K+A  FS   +G+L DEPT+
Sbjct  69   HISQLGGIEIETVEDRAMLSRLGVSNVQNDTMSGGEETRAKIAAAFSQQVHGILADEPTS  128

Query  129  HLDEAGIQFLIEKLSYYPGALVLVSHDRYVLDKLVTKIWEIENGTVTEYPGNYSDYVAqk  188
            HLD  GI++LI +L  + GAL+++SHDRY LD +V KIWE+ +G +TEY G YSDY+ QK
Sbjct  129  HLDLNGIDLLIGQLKAFDGALLVISHDRYFLDMVVDKIWELKDGKITEYWGGYSDYLRQK  188

Query  189  elqqkqqqeqhekyvkekSRLmkaaeekmkkaDKITQANGHINKKETKAKANKMFMTKSK  248
            E ++++Q  + E  +KE+ RL  A +EK ++A+++ + +   + K++   A ++  +K  
Sbjct  189  EEERQHQAVEYELMMKERERLESAVQEKRQQANRLDNKKKGEKSKNSTESAGRLGHAKMT  248

Query  249  DTSQKAVQRAAKAIEQRVEQLVEVKAPEEQKTLHFHQPIALQLHNKFPIMADRITLKVGD  308
            +T Q+ + +AAK++E+R+  L +++APE+ ++++F+Q+ AL+LHNKFPI AD ++LK G 
Sbjct  249  GTKQRKLYQAAKSMEKRLAALEDIQAPEHLRSIRFRQSSALELHNKFPITADGLSLKFGS  308

Query  309  KTLLNEASFQFPLGRTIAITGNNGSGKTTLLRHIINKGEGMIISPKVVLGSYEQLGYQFN  368
            +T++++A+F +PLG  +AITG+NG+GKT+LL+ I ++++G+ ISPK  +G + Q GY+FN
Sbjct  309  RTIFDDANFIIPLGAKVAITGSNGTGKTSLLKMISERADGLTISPKAEIGYFTQTGYKFN  368

Query  369  KNETVMTFMKERSDHPESKIHEVLYEMNFTGNDLKKNVCNLSGGEAIRLVLCQLFLGRYN  428
             + +V++FM+E  +   + I+ VL  M + +ND++KN+ +LSGGE I+L+L +++LG+YN
Sbjct  369  THKSVLSFMQEECEYTVAEIRAVLASMGIGANDIQKNLSDLSGGEIIKLLLSKMLLGKYN  428

Query  429  VLLLDEPTNFLDVLCIEALERFLKAYEGTVILVSHDRRFINRVADCTFVIEDQQL  483
            +LL+DEP N+LD+  I ALE  +K+Y GT+I+VSHD+++++ +AD  + I D+++
Sbjct  429  ILLMDEPGNYLDLKSIAALETMMKSYAGTIIFVSHDKQLVDNIADIIYEIKDHKI  483

35) OB0699 in NC_004193


> NC_016808_R1|79|G72|378774001|YP_005176244.1|Pasteurella_multocida_36950|+|67348..68823|msr(E)|Pmu_03460|macrolide 
efflux 
protein
Length=491

 Score =  299 bits (1119),  Expect = 3e-82, Method: Compositional matrix adjust.
 Identities = 201/479 (42%), Positives = 347/479 (73%), Gaps = 9/479 (1%)

Query  10   NIELTYLDKEILKIDRLAIHQFDRIGIVgkngsgkssllkllagkIKPNKGIVHQHASYA  69
            NI L Y ++++L ID L IH +DRIG+VG NG+GKSSLLK+L G I    + +++ + +A
Sbjct  9    NIRLDYAGRDVLDIDELEIHSYDRIGLVGDNGAGKSSLLKVLNGEIVLAEATLQRFGDFA  68

Query  70   YFEQMEAPDLHLTGNEDPALLGKLHVPS-QLDSISGGEQTRLKLTQLLSEYREALFIDEP  128
             + Q+ + +++    ED A+L++L V++ Q D++SGGE+TR K++  +S+  ++++ DEP
Sbjct  69   HISQLGGIEIETV--EDRAMLSRLGVSNVQNDTMSGGEETRAKIAAAFSQQVHGILADEP  126

Query  129  TTHLDQDGVAFIQSELEYYYGALVLVSHDRTLLDQLVSTIWEIHDGSVFVYAGNYTeyek  188
            T+HLD +G+ ++ ++L  + GAL+++SHDR +LD +V  IWE+ DG +  Y G Y++Y +
Sbjct  127  TSHLDLNGIDLLIGQLKAFDGALLVISHDRYFLDMVVDKIWELKDGKITEYWGGYSDYLR  186

Query  189  qkqlefeqqqeAHYQYV-KEKSRLEKAADQKRSKATKM---MKGDKANVRAKEGVNRMFA  244
            QK+ E ++Q   +Y+ + KE+ RLE A ++KR +A ++    KG+K++  + E+  R+  
Sbjct  187  QKEEERQHQA-VEYELMMKERERLESAVQEKRQQANRLDNKKKGEKSK-NSTESAGRLGH  244

Query  245  TKSKDATQKAMQKSAKAIEKRIDQLEEVRAPESSNPINFYKSKALDLHNKFPIIGDQLTL  304
            +K  ++ Q+ + ++AK++EKR+  LE+++APE   +I F +S AL+LHNKFPI +D L+L
Sbjct  245  AKMTGTKQRKLYQAAKSMEKRLAALEDIQAPEHLRSIRFRQSSALELHNKFPITADGLSL  304

Query  305  QAGDKVLLEEARFQFPLGENIAITGGNGVGKSSLLQHIVQRGHALDISPKVTFGYFQQLG  364
            + G + ++++A F +PLG ++AITG+NG GK+SLL+ I +R+++L ISPK  +GYF Q G
Sbjct  305  KFGSRTIFDDANFIIPLGAKVAITGSNGTGKTSLLKMISERADGLTISPKAEIGYFTQTG  364

Query  365  YQREINETVLEFLQKRTEYEEGFLRSVLHSMYFSGNDLRKKLNQLSGGESIRLQLSYLFL  424
            Y+ + + +VL F+Q   EY  + +R+VL SM +++ND++K+L++LSGGE I+L LS ++L
Sbjct  365  YKFNTHKSVLSFMQEECEYTVAEIRAVLASMGIGANDIQKNLSDLSGGEIIKLLLSKMLL  424

Query  425  GKFHILILDEPTNFLDIPTIQALENFFHAYPGTIVFVSHDQTFINQVATKQFVIQNKKL  483
            GK++IL++DEP N+LD+ +I ALE    +Y+GTI+FVSHD+ +++++A   + I++ K+
Sbjct  425  GKYNILLMDEPGNYLDLKSIAALETMMKSYAGTIIFVSHDKQLVDNIADIIYEIKDHKI  483


 Score = 47.7 bits (161),  Expect = 2e-06, Method: Compositional matrix adjust.
 Identities = 30/89 (34%), Positives = 58/89 (66%), Gaps = 2/89 (2%)

Query  90   LGKLHVPSQLDSISGGEQTRLKLTQ-LLSEYREALFIDEPTTHLDQDGVAFIQSELEYYY  148
            +G  ++  +L  +SGGE  +L L++ LL+ Y + L++DEP   LD  ++A +++ +  Y 
Sbjct  397  IGANDIQKNLSDLSGGEIIKLLLSKMLLGKY-NILLMDEPGNYLDLKSIAALETMMKSYA  455

Query  149  GALVLVSHDRTLLDQLVSTIWEIHDGSVF  177
            G++++VSHD+ L+D++   I EI D  ++
Sbjct  456  GTIIFVSHDKQLVDNIADIIYEIKDHKII  484


 Score = 45.3 bits (152),  Expect = 9e-06, Method: Compositional matrix adjust.
 Identities = 42/163 (26%), Positives = 92/163 (57%), Gaps = 17/163 (10%)

Query  323  ENIAITGGNGVGKSSLLQHIVQRGHALDISPKVTFGYFQQLGYQREINETVLEFLQKRTE  382
            + I++ G+NG GKSSLL+ +++    L  +    FG F +++   ++    +E ++ R+ 
Sbjct  31   DRIGLVGDNGAGKSSLLK-VLNGEIVLAEATLQRFGDFAHIS---QLGGIEIETVEDRA-  85

Query  383  YEEGFLRSVLHSMYFSGNDLRKKLNQLSGGESIRLQLSYLFLGKFHILILDEPTNFLDIP  442
                    +L  +  + +++++  + +SGGE  R +++  F  + H ++ DEPT+ LD+ 
Sbjct  86   --------MLSRL--GVSNVQN--DTMSGGEETRAKIAAAFSQQVHGILADEPTSHLDLN  133

Query  443  TIQALENFFHAYPGTIVFVSHDQTFINQVATKQFVIQNKKLYE  485
             I+ L   + A+ G+++ +SHD+ F++ V  K   +++ K+ E
Sbjct  134  GIDLLIGQLKAFDGALLVISHDRYFLDMVVDKIWELKDGKITE  176

36) SSIL_2504 in NC_018065


> NC_016808_R1|79|G72|378774001|YP_005176244.1|Pasteurella_multocida_36950|+|67348..68823|msr(E)|Pmu_03460|macrolide 
efflux 
protein
Length=491

 Score =  291 bits (1088),  Expect = 9e-80, Method: Compositional matrix adjust.
 Identities = 197/483 (41%), Positives = 333/483 (69%), Gaps = 5/483 (1%)

Query  3    NLSFELKNIHVQFLDKDILAIPQLAIYQFDRIGIVGKNGAGKSTLLKILTGQLVPQQGNV  62
            +L +  +NI++++ ++D+L I +L I  +DRIG+VG NGAGKS+LLK+L G++V  ++ +
Sbjct  2    SLIIKARNIRLDYAGRDVLDIDELEIHSYDRIGLVGDNGAGKSSLLKVLNGEIVLAEATL  61

Query  63   SSHVDYYYFEQTSPAFTQHNIDIALLHKLKAVDPH----SGGELTRLKLSQAFSHYYEAL  118
                D+  + Q +    +   D A+L +L   + +    SGGE TR K++ AFS+  +++
Sbjct  62   QRFGDFAHISQLGGIEIETVEDRAMLSRLGVSNVQNDTMSGGEETRAKIAAAFSQQVHGI  121

Query  119  IFDEPTTHLDRKGIRFLQDQLRDYYGAVVLVSHDRNLLDSVVTTIWEVNDGQVSFYSGNY  178
            + DEPT+HLD +GI +L +QL+ + GA++++SHDR +LD VV  IWE++DG+++ Y G Y
Sbjct  122  LADEPTSHLDLNGIDLLIGQLKAFDGALLVISHDRYFLDMVVDKIWELKDGKITEYWGGY  181

Query  179  SDYSAQKEREKHEQAAAHEKYVREKAHLekavaekmkkaekIteakklskk-etkakaNR  237
            SDY  QKE E+++QA   E  ++E+ +LE AV EK ++A+++ + KK  K  ++   A R
Sbjct  182  SDYLRQKEEERQHQAVEYELMMKERERLESAVQEKRQQANRLDNKKKGEKSKNSTESAGR  241

Query  238  MFETKSKGTSQKAAYRSAKAMEKRIEQLPVVEKVKEDVPLHFKQSKALELHNKVPIMMQD  297
            + ++K  GT Q+  Y++AK+MEKR+  L  ++   +  +++F+QS ALELHNK PI  ++
Sbjct  242  LGHAKMTGTKQRKLYQAAKSMEKRLAALEDIQAPEHLRSIRFRQSSALELHNKFPITADG  301

Query  298  FTLSIRKKILIDQCQLQVRLQDKIALTGPNGSGKSTLLQAMIEKHPHMDLSPKVKIGHFS  357
            ++L +  + ++D+ ++ + L  K+A+TG+NG+GK++LL+ + E+   + +SPK  IG F+
Sbjct  302  LSLKFGSRTIFDDANFIIPLGAKVAITGSNGTGKTSLLKMISERADGLTISPKAEIGYFT  361

Query  358  QLAYQNLPDETVWSFIKTRSEYSDAFIRTVLHQMQFDQSDLQKRITVLSGGERIRLLLSE  417
            Q +Y+   + +V SF++   EY+ A IR+VL  M ++ +D+QK ++ LSGGE I+LLLS 
Sbjct  362  QTGYKFNTHKSVLSFMQEECEYTVAEIRAVLASMGIGANDIQKNLSDLSGGEIIKLLLSK  421

Query  418  LFLGQYNILLLDEPTNFLDMATKEALVNFIRAYDGTILFVSHDDYFVKQVATRIIEIKDR  477
            ++LG+YNILL+DEP N+LD+ +  AL   +++Y GTI+FVSHD  +V ++A  I EIKD+
Sbjct  422  MLLGKYNILLMDEPGNYLDLKSIAALETMMKSYAGTIIFVSHDKQLVDNIADIIYEIKDH  481

Query  478  ALI  480
             +I
Sbjct  482  KII  484


 Score = 56.3 bits (194),  Expect = 4e-09, Method: Compositional matrix adjust.
 Identities = 51/172 (30%), Positives = 103/172 (60%), Gaps = 21/172 (12%)

Query  312  QLQVRLQDKIALTGPNGSGKSTLLQAMIEKHPHMDLSPKV--KIGHFSQLAYQNLPDETV  369
            +L+++  D+I+L G NG+GKS+LL+ +   + ++ L+     ++G+F++++  +L +  +
Sbjct  24   ELEIHSYDRIGLVGDNGAGKSSLLKVL---NGEIVLAEATLQRFGDFAHIS--QLGGIEI  78

Query  370  WSFIKTRSEYSDAFIRTVLHQMQFDQSDLQKRITVLSGGERIRLLLSELFLGQYNILLLD  429
                    E  +   R++L ++  + S++Q+    +SGGE  R  ++  F  Q + +L D
Sbjct  79   --------ETVED--RAMLSRL--GVSNVQN--DTMSGGEETRAKIAAAFSQQVHGILAD  124

Query  430  EPTNFLDMATKEALVNFIRAYDGTILFVSHDDYFVKQVATRIIEIKDRALIE  481
            EPT+ LD+   + L+  ++A+DG++L +SHD YF+  V  +I E+KD  + E
Sbjct  125  EPTSHLDLNGIDLLIGQLKAFDGALLVISHDRYFLDMVVDKIWELKDGKITE  176

37) MC28_4411 in NC_018693


> NC_016808_R1|79|G72|378774001|YP_005176244.1|Pasteurella_multocida_36950|+|67348..68823|msr(E)|Pmu_03460|macrolide 
efflux 
protein
Length=491

 Score =  254 bits (948),  Expect = 1e-68, Method: Compositional matrix adjust.
 Identities = 192/475 (41%), Positives = 320/475 (68%), Gaps = 10/475 (2%)

Query  6    ARNIEKSFGDRTIFTLPSLEIHAHDRIGIVGVNGAGKSTLLQILSKEIEADKGTVTHHSS  65
            ARNI   +++R ++ +  LEIH+ DRIG+VG NGAGKS+LL++L+ EI    +T+ + + 
Sbjct  7    ARNIRLDYAGRDVLDIDELEIHSYDRIGLVGDNGAGKSSLLKVLNGEIVLAEATLQRFGD  66

Query  66   IAIIPQLSDTILETASSLAK-GKWSISNV-ANSMSGGERMRLKIAHALEQDAGILFADEP  123
            +A I+QL++  +ET    A  ++ ++SNV  ++MSGGE  R KIA A+ Q+   ++ADEP
Sbjct  67   FAHISQLGGIEIETVEDRAMLSRLGVSNVQNDTMSGGEETRAKIAAAFSQQVHGILADEP  126

Query  124  TSHLDMAGTEQLEKALLSYKGALVLISHDRDFLDNICTKIIEIEDGMIQEYKGNYSNYRK  183
            TSHLD+ G + L   L ++ GAL++ISHDR FLD +  KI E+ DG I EY G YS+Y +
Sbjct  127  TSHLDLNGIDLLIGQLKAFDGALLVISHDRYFLDMVVDKIWELKDGKITEYWGGYSDYLR  186

Query  184  QKERERIQKQAEYEQYIQEKNRLEQSISQKKQRASSMTKI-----PTRFSSSESKL--YK  236
            QKE ER ++  EYE  ++E++RLE ++ +K+Q+A+ + +      +   + S ++L   K
Sbjct  187  QKEEERQHQAVEYELMMKERERLESAVQEKRQQANRLDNKKKGEKSKNSTESAGRLGHAK  246

Query  237  LSGAHGQEQVSkaakaletrleklekkekpkdlSQAQFDVQYHTPIHSKVAVQFNKATKK  296
            ++G+  Q ++ +AAK++E RL  LE  + P +L   +F       +H+K ++  +  + K
Sbjct  247  MTGTK-QRKLYQAAKSMEKRLAALEDIQAPEHLRSIRFRQSSALELHNKFPITADGLSLK  305

Query  297  IGDRTLFKNMNGTIAPGAKLAILGANGSGKTTLFNMLLTNERGIQLSKSCKIGYFEQALS  356
            +G RT+F + N  I+ GAK+AI G+NG+GKT+L++M+     G+ +S    IGYF Q+  
Sbjct  306  FGSRTIFDDANFIIPLGAKVAITGSNGTGKTSLLKMISERADGLTISPKAEIGYFTQTGY  365

Query  357  ILKTDKTILENVLEETNYTEAFVRTILARLLFRREDVHKPVHVLSGGERMKVALAKVFLG  416
             ++T+K++L  + EE +YT A +R++LA + +  +D++K +  LSGGE +K+ L+K++LG
Sbjct  366  KFNTHKSVLSFMQEECEYTVAEIRAVLASMGIGANDIQKNLSDLSGGEIIKLLLSKMLLG  425

Query  417  NYNMLLLDEPTNYLDLTTQEELENMLQEYPGTILFISHDRAFIRSVADHILQVDE  471
            +YN+LL+DEP NYLDL +   LE M++ Y+GTI+F+SHD+ ++ ++AD I ++ +
Sbjct  426  KYNILLMDEPGNYLDLKSIAALETMMKSYAGTIIFVSHDKQLVDNIADIIYEIKD  480


 Score = 61.8 bits (215),  Expect = 1e-10, Method: Compositional matrix adjust.
 Identities = 55/178 (31%), Positives = 100/178 (57%), Gaps = 19/178 (10%)

Query  13   FGDRTIFTLPSLEIHAHDRIGIVGVNGAGKSTLLQILSKEIEA----DKGTV--------  60
            FG RTIF  +++ I    +++I G NG+GK++LL+++S   ++     K+ +        
Sbjct  306  FGSRTIFDDANFIIPLGAKVAITGSNGTGKTSLLKMISERADGLTISPKAEIGYFTQTGY  365

Query  61   ---THHSSIAIIPQLSD-TILETASSLAK---GKWSISNVANSMSGGERMRLKIAHALEQ  113
               TH S ++++ +  + T+ E  + LA    G   I +  + +SGGE ++L ++  L  
Sbjct  366  KFNTHKSVLSFMQEECEYTVAEIRAVLASMGIGANDIQKNLSDLSGGEIIKLLLSKMLLG  425

Query  114  DAGILFADEPTSHLDMAGTEQLEKALLSYKGALVLISHDRDFLDNICTKIIEIEDGMI  171
               IL+ DEP + LD+ +   LE  + SY G+++++SHD++++DNI   I EI D  I
Sbjct  426  KYNILLMDEPGNYLDLKSIAALETMMKSYAGTIIFVSHDKQLVDNIADIIYEIKDHKI  483


 Score = 58.9 bits (204),  Expect = 9e-10, Method: Compositional matrix adjust.
 Identities = 47/180 (27%), Positives = 98/180 (55%), Gaps = 21/180 (11%)

Query  314  AKLAILGANGSGKTTLFNMLLTNERGIQLSKSC--KIGYFEQALSILKTDKTILENVLEE  371
             +++++G NG+GK++L+++L   +  I L+ +   ++G F +   +   +   +E+    
Sbjct  31   DRIGLVGDNGAGKSSLLKVL---NGEIVLAEATLQRFGDFAHISQLGGIEIETVED----  83

Query  372  TNYTEAFVRTILARLLFRREDVHKPVHVLSGGERMKVALAKVFLGNYNMLLLDEPTNYLD  431
                    R++L+RL     +V++  + +SGGE  +  +A  F  + + +L DEPT+ LD
Sbjct  84   --------RAMLSRL--GVSNVQN--DTMSGGEETRAKIAAAFSQQVHGILADEPTSHLD  131

Query  432  LTTQEELENMLQEYPGTILFISHDRAFIRSVADHILQVDESEPRIFYGNYEQYIKRTTQA  491
            L   + L   L+ + G++L ISHDR F+  V D I ++ ++    + G Y +Y+++  + 
Sbjct  132  LNGIDLLIGQLKAFDGALLVISHDRYFLDMVVDKIWELKDGKITEYWGGYSDYLRQKEEE  191