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Homologs of HMPREF0351_12133 gene of NC_017960_P1

protein-level

Hit (GenBank Accn)

Product

Source Genome

Eval.

Ident.(%)

1) HMPREF0351_12133
( YP_006376739.1 )

bacteriophage endonuclease

NC_017960
(Enterococcus faecium DO)

3e-54

100

2) BN194_30280
( YP_006753094.1 )

HNH endonuclease

NC_018641
(Lactobacillus casei W56)

4e-28

3) JDM1_0040
( YP_003061626.1 )

prophage Lp3 protein 12

NC_012984
(Lactobacillus plantarum JDM1)

2e-25

4) Lp16_1958
( YP_008121774.1 )

prophage P2b protein 12, endonuclease

NC_021514
(Lactobacillus plantarum 16)

4e-25

5) lp_2469
( YP_004890156.1 )

prophage P2b protein 12, endonuclease

NC_004567
(Lactobacillus plantarum WCFS1)

1e-24

6) LBP_cg2001
( YP_007987678.1 )

Prophage Lp3 protein 12

NC_021224
(Lactobacillus plantarum P-8)

8e-25

7) LCBD_3110
( YP_005861140.1 )

HNH endonuclease

NC_017474
(Lactobacillus casei BD-II)

2e-23

8) sb56
( YP_003172642.1 )

phage-related HNH endonuclease

NC_013198
(Lactobacillus rhamnosus GG)

1e-20

9) sb56
( YP_003173381.1 )

phage-related HNH endonuclease

NC_013199
(Lactobacillus rhamnosus Lc 705)

1e-20

10) LC705_01070
( YP_003173760.1 )

phage-related HNH endonuclease

NC_013199
(Lactobacillus rhamnosus Lc 705)

1e-20

11) LRHM_2788
( YP_005867280.1 )

phage protein

NC_017482
(Lactobacillus rhamnosus GG)

2e-20

12) LBPG_01495
( YP_008448015.1 )

hypothetical protein

NC_022112
(Lactobacillus paracasei 8700:2)

3e-20

13) PECL_595
( YP_005004569.1 )

HNH endonuclease family protein, phage-related protein

NC_016605
(Pediococcus claussenii ATCC BAA-344)

1e-19

14) LCAZH_1007
( YP_003788100.1 )

HNH endonuclease

NC_014334
(Lactobacillus casei Zhang)

4e-17

• Sequence Alignments

1) HMPREF0351_12133 in NC_017960


> NC_017960_P1|9|G9|389869316|YP_006376739.1|Enterococcus_faecium_DO|-|6031..6411|-|HMPREF0351_12133|bacteriophage 
endonuclease
Length=126

 Score =  204 bits (759),  Expect = 3e-54, Method: Compositional matrix adjust.
 Identities = 126/126 (100%), Positives = 126/126 (100%), Gaps = 0/126 (0%)

Query  1    MAVKKQCNHAGCKTLIDYRQKYCGKHKAKQTAIKREERKQSEGKYFQFYQSRTWRKASYL  60
            MAVKKQCNHAGCKTLIDYRQKYCGKHKAKQTAIKREERKQSEGKYFQFYQSRTWRKASYL
Sbjct  1    MAVKKQCNHAGCKTLIDYRQKYCGKHKAKQTAIKREERKQSEGKYFQFYQSRTWRKASYL  60

Query  61   YRLNHPVCEDCLEEGLIRKADVVDHKIELKDDWNRRLDETNFRSLCHAHHNSKTANERQR  120
            YRLNHPVCEDCLEEGLIRKADVVDHKIELKDDWNRRLDETNFRSLCHAHHNSKTANERQR
Sbjct  61   YRLNHPVCEDCLEEGLIRKADVVDHKIELKDDWNRRLDETNFRSLCHAHHNSKTANERQR  120

Query  121  REKSTL  126
            REKSTL
Sbjct  121  REKSTL  126

2) BN194_30280 in NC_018641


> NC_017960_P1|9|G9|389869316|YP_006376739.1|Enterococcus_faecium_DO|-|6031..6411|-|HMPREF0351_12133|bacteriophage 
endonuclease
Length=126

 Score =  118 bits (429),  Expect = 4e-28, Method: Compositional matrix adjust.
 Identities = 61/122 (50%), Positives = 88/122 (73%), Gaps = 3/122 (2%)

Query  2    IMKLCNHAGCNTMVPFNQRYCDKHQPEPRASDNERYAYRKAIGGRYFKFYKSKAWRKLSY  61
            + K CNHAGC+T++ + Q+YC+KH++   A   E    RK   G+YF+FY+S++WRK SY
Sbjct  3    VKKQCNHAGCKTLIDYRQKYCGKHKAKQTAIKREE---RKQSEGKYFQFYQSRTWRKASY  59

Query  62   SYRLAHPLCERCQANGLYVQAQVVDHRVPIRVDWSRRLDETNLQSLCNACHGTKTKVEDA  121
             YRL HP+CE C  +GL  +A+VVDH++ ++ DW+RRLDETN++SLC+A H +KT  E  
Sbjct  60   LYRLNHPVCEDCLEEGLIRKADVVDHKIELKDDWNRRLDETNFRSLCHAHHNSKTANERQ  119

Query  122  AR  123
             R
Sbjct  120  RR  121

3) JDM1_0040 in NC_012984


> NC_017960_P1|9|G9|389869316|YP_006376739.1|Enterococcus_faecium_DO|-|6031..6411|-|HMPREF0351_12133|bacteriophage 
endonuclease
Length=126

 Score =  108 bits (394),  Expect = 2e-25, Method: Compositional matrix adjust.
 Identities = 63/124 (51%), Positives = 90/124 (73%), Gaps = 2/124 (1%)

Query  5    MKQCEHPGCRTLVAYDTRYCEKHRKATNKWRYHKRMYDSDESKYQQFYKSSAWRKLSRRF  64
             KQC+H+GC+TL+ Y  +YC KH+      + + R     E+KY QFY+S +WRK S  +
Sbjct  4    KKQCNHAGCKTLIDYRQKYCGKHKAKQTAIKREERK--QSEGKYFQFYQSRTWRKASYLY  61

Query  65   LESNPVCVQCYQDGVIRKANVVDHVIEIKDDWSRRLDESNLQSLCHRHHNRKTRLVREQR  124
              ++PVC +C ++G+IRKA+VVDH IE+KDDW+RRLDE+N++SLCH HHN KT   R++R
Sbjct  62   RLNHPVCEDCLEEGLIRKADVVDHKIELKDDWNRRLDETNFRSLCHAHHNSKTANERQRR  121

Query  125  EQQT  128
            E+ T
Sbjct  122  EKST  125

4) Lp16_1958 in NC_021514


> NC_017960_P1|9|G9|389869316|YP_006376739.1|Enterococcus_faecium_DO|-|6031..6411|-|HMPREF0351_12133|bacteriophage 
endonuclease
Length=126

 Score =  108 bits (391),  Expect = 4e-25, Method: Compositional matrix adjust.
 Identities = 62/124 (50%), Positives = 90/124 (73%), Gaps = 2/124 (1%)

Query  5    MKQCEHPGCRTLVAYDTRYCEKHRKATNKWRYHKRMYDSDESKYQQFYKSSAWRKLSRRF  64
             KQC+H+GC+TL+ Y  +YC KH+      + + R     E+KY QFY+S +WRK S  +
Sbjct  4    KKQCNHAGCKTLIDYRQKYCGKHKAKQTAIKREERK--QSEGKYFQFYQSRTWRKASYLY  61

Query  65   LESNPVCVQCYQDGVIRKADVVDHVIEIKDDWSRRLDESNLQPLCYRHHNRKTRLAREQR  124
              ++PVC +C ++G+IRKADVVDH IE+KDDW+RRLDE+N+++LC  HHN KT   R++R
Sbjct  62   RLNHPVCEDCLEEGLIRKADVVDHKIELKDDWNRRLDETNFRSLCHAHHNSKTANERQRR  121

Query  125  EQPT  128
            E++T
Sbjct  122  EKST  125

5) lp_2469 in NC_004567


> NC_017960_P1|9|G9|389869316|YP_006376739.1|Enterococcus_faecium_DO|-|6031..6411|-|HMPREF0351_12133|bacteriophage 
endonuclease
Length=126

 Score =  106 bits (384),  Expect = 1e-24, Method: Compositional matrix adjust.
 Identities = 60/124 (49%), Positives = 89/124 (72%), Gaps = 2/124 (1%)

Query  5    MKQCEHPGCRTLVAYDTRYCEKHRKATNKWRYHKRMYDSDESKYQQFYKSSAWRKLSRRF  64
             KQC+H+GC+TL+ Y  +YC KH+      + + R     E+KY QFY+S +WRK S  +
Sbjct  4    KKQCNHAGCKTLIDYRQKYCGKHKAKQTAIKREERK--QSEGKYFQFYQSRTWRKASYLY  61

Query  65   LESNPVCVQCYQDNVIRKANVVDHVIEIKDDWSRRLDESNLQPLCYRHHNRKTRLAREQR  124
              ++PVC +C ++ +IRKA+VVDH IE+KDDW+RRLDE+N+++LC  HHN KT   R++R
Sbjct  62   RLNHPVCEDCLEEGLIRKADVVDHKIELKDDWNRRLDETNFRSLCHAHHNSKTANERQRR  121

Query  125  EQTT  128
            E++T
Sbjct  122  EKST  125

6) LBP_cg2001 in NC_021224


> NC_017960_P1|9|G9|389869316|YP_006376739.1|Enterococcus_faecium_DO|-|6031..6411|-|HMPREF0351_12133|bacteriophage 
endonuclease
Length=126

 Score =  106 bits (387),  Expect = 8e-25, Method: Compositional matrix adjust.
 Identities = 60/123 (49%), Positives = 89/123 (73%), Gaps = 2/123 (1%)

Query  8    KMCEHPGCRTLVAYDTRYCEKHRKATNKWRYHKRMYDSDESKYQQFYKSSAWRKLSRWFL  67
            K C+H+GC+TL+ Y  +YC KH+      + + R     E+KY QFY+S +WRK S  + 
Sbjct  5    KQCNHAGCKTLIDYRQKYCGKHKAKQTAIKREERK--QSEGKYFQFYQSRTWRKASYLYR  62

Query  68   ESNPVCVQCYQDGVIRKADVVDHVIEIKDDWSRRLDESNLQPLCYRHHNRKTGLVREQRK  127
             ++PVC +C ++G+IRKADVVDH IE+KDDW+RRLDE+N+++LC  HHN KT+  R++R 
Sbjct  63   LNHPVCEDCLEEGLIRKADVVDHKIELKDDWNRRLDETNFRSLCHAHHNSKTANERQRRE  122

Query  128  QPT  130
            ++T
Sbjct  123  KST  125

7) LCBD_3110 in NC_017474


> NC_017960_P1|9|G9|389869316|YP_006376739.1|Enterococcus_faecium_DO|-|6031..6411|-|HMPREF0351_12133|bacteriophage 
endonuclease
Length=126

 Score =  102 bits (369),  Expect = 2e-23, Method: Compositional matrix adjust.
 Identities = 53/110 (49%), Positives = 78/110 (71%), Gaps = 3/110 (2%)

Query  1    MVPFNQRYCDKHQPEPRASDNERYAYRKAIGGRYFKFYKSKAWRKLSYSYRLAHPLCERC  60
            ++ + Q+YC+KH++   A   E    RK   G+YF+FY+S++WRK SY YRL HP+CE C
Sbjct  15   LIDYRQKYCGKHKAKQTAIKREE---RKQSEGKYFQFYQSRTWRKASYLYRLNHPVCEDC  71

Query  61   QANGLYVQAQVVDHRVPIRVDWSRRLDETNLQSLCNACHGTKTKVEDAAR  110
              +GL  +A+VVDH++ ++ DW+RRLDETN++SLC+A H +KT  E   R
Sbjct  72   LEEGLIRKADVVDHKIELKDDWNRRLDETNFRSLCHAHHNSKTANERQRR  121

8) sb56 in NC_013198


> NC_017960_P1|9|G9|389869316|YP_006376739.1|Enterococcus_faecium_DO|-|6031..6411|-|HMPREF0351_12133|bacteriophage 
endonuclease
Length=126

 Score = 92.8 bits (333),  Expect = 1e-20, Method: Compositional matrix adjust.
 Identities = 52/118 (45%), Positives = 78/118 (67%), Gaps = 3/118 (2%)

Query  10   CMHPGCRRMIPFNQRFCEEHKQDKSKQATNQERMQYEEKELRFYKSTTWTKLSKSFRLRN  69
            C H+GC+ +I + Q++C  HK  K      +ER Q E K ++FY+S TW K S  +RL +
Sbjct  7    CNHAGCKTLIDYRQKYCGKHK-AKQTAIKREERKQSEGKYFQFYQSRTWRKASYLYRLNH  65

Query  70   PTCASCLKRGIIRQAVLVDHIEPIKTAYGWQHRLDESNLQSLCQTCHNAKTAREVAQR  127
            P C  CL  G+IR+A +VDH   +K   +W++RLDE+N++SLC++ HN+KTA E  +R
Sbjct  66   PVCEDCLEEGLIRKADVVDHKIELKD--DWNRRLDETNFRSLCHAHHNSKTANERQRR  121

9) sb56 in NC_013199


> NC_017960_P1|9|G9|389869316|YP_006376739.1|Enterococcus_faecium_DO|-|6031..6411|-|HMPREF0351_12133|bacteriophage 
endonuclease
Length=126

 Score = 92.8 bits (333),  Expect = 1e-20, Method: Compositional matrix adjust.
 Identities = 52/118 (45%), Positives = 78/118 (67%), Gaps = 3/118 (2%)

Query  10   CMHPGCRRMIPFNQRFCEEHKQDKSKQATNQERMQYEEKELRFYKSTTWTKLSKSFRLRN  69
            C H+GC+ +I + Q++C  HK  K      +ER Q E K ++FY+S TW K S  +RL +
Sbjct  7    CNHAGCKTLIDYRQKYCGKHK-AKQTAIKREERKQSEGKYFQFYQSRTWRKASYLYRLNH  65

Query  70   PTCASCLKRGIIRQAVLVDHIEPIKTAYGWQHRLDESNLQSLCQTCHNAKTAREVAQR  127
            P C  CL  G+IR+A +VDH   +K   +W++RLDE+N++SLC++ HN+KTA E  +R
Sbjct  66   PVCEDCLEEGLIRKADVVDHKIELKD--DWNRRLDETNFRSLCHAHHNSKTANERQRR  121

10) LC705_01070 in NC_013199


> NC_017960_P1|9|G9|389869316|YP_006376739.1|Enterococcus_faecium_DO|-|6031..6411|-|HMPREF0351_12133|bacteriophage 
endonuclease
Length=126

 Score = 92.8 bits (333),  Expect = 1e-20, Method: Compositional matrix adjust.
 Identities = 52/118 (45%), Positives = 79/118 (67%), Gaps = 3/118 (2%)

Query  8    CMHPGCRRMIPFNQRFCEEHKQDKNKQATNQERMQYEEKELRFYKSTTWTKLSKSFRLRN  67
            C H+GC+ +I + Q++C  HK  K+     +ER Q E K ++FY+S TW K S  +RL +
Sbjct  7    CNHAGCKTLIDYRQKYCGKHK-AKQTAIKREERKQSEGKYFQFYQSRTWRKASYLYRLNH  65

Query  68   PTCATCLKRGIIRQAVLVDHIEPIKTAYGWQHRLDESNLQSLCQTCHNAKTAREVAQR  125
            P C  CL  G+IR+A +VDH   +K   +W++RLDE+N++SLC++ HN+KTA E  +R
Sbjct  66   PVCEDCLEEGLIRKADVVDHKIELKD--DWNRRLDETNFRSLCHAHHNSKTANERQRR  121

11) LRHM_2788 in NC_017482


> NC_017960_P1|9|G9|389869316|YP_006376739.1|Enterococcus_faecium_DO|-|6031..6411|-|HMPREF0351_12133|bacteriophage 
endonuclease
Length=126

 Score = 92.8 bits (333),  Expect = 2e-20, Method: Compositional matrix adjust.
 Identities = 52/118 (45%), Positives = 78/118 (67%), Gaps = 3/118 (2%)

Query  8    CMHPGCRRMIPFNQRFCEEHKQDKSKQATNQERMQYEEKELRFYKSTTWTKLSKSFRLRN  67
            C H+GC+ +I + Q++C  HK  K      +ER Q E K ++FY+S TW K S  +RL +
Sbjct  7    CNHAGCKTLIDYRQKYCGKHK-AKQTAIKREERKQSEGKYFQFYQSRTWRKASYLYRLNH  65

Query  68   PTCASCLKRGIIRQAVLVDHIEPIKTAYGWQHRLDESNLQSLCQTCHNAKTAREVAQR  125
            P C  CL  G+IR+A +VDH   +K   +W++RLDE+N++SLC++ HN+KTA E  +R
Sbjct  66   PVCEDCLEEGLIRKADVVDHKIELKD--DWNRRLDETNFRSLCHAHHNSKTANERQRR  121

12) LBPG_01495 in NC_022112


> NC_017960_P1|9|G9|389869316|YP_006376739.1|Enterococcus_faecium_DO|-|6031..6411|-|HMPREF0351_12133|bacteriophage 
endonuclease
Length=126

 Score = 91.8 bits (329),  Expect = 3e-20, Method: Compositional matrix adjust.
 Identities = 54/123 (44%), Positives = 82/123 (67%), Gaps = 4/123 (3%)

Query  8    CMHPGCRRMIPFNQRFCEEHQQDKNKQATNQERMQYEEKELRFYKSTTWTKLSKSFRLRN  67
            C H+GC+ +I + Q++C  H+  K+     +ER Q E K ++FY+S TW K S  +RL +
Sbjct  7    CNHAGCKTLIDYRQKYCGKHK-AKQTAIKREERKQSEGKYFQFYQSRTWRKASYLYRLNH  65

Query  68   PTCASCLKRGIIRQAVLVDHIEPIKTAYGWQHRLDESNLQSLCQTCHNAKTAREVAQRRM  127
            P C  CL  G+IR+A +VDH   +K   +W++RLDE+N++SLC++ HN+KTA E  QRR 
Sbjct  66   PVCEDCLEEGLIRKADVVDHKIELKD--DWNRRLDETNFRSLCHAHHNSKTANE-RQRRE  122

Query  128  RSP  130
            +S 
Sbjct  123  KST  125

13) PECL_595 in NC_016605


> NC_017960_P1|9|G9|389869316|YP_006376739.1|Enterococcus_faecium_DO|-|6031..6411|-|HMPREF0351_12133|bacteriophage 
endonuclease
Length=126

 Score = 89.9 bits (322),  Expect = 1e-19, Method: Compositional matrix adjust.
 Identities = 53/123 (44%), Positives = 80/123 (66%), Gaps = 2/123 (1%)

Query  2    AKKFCNHAGCRALVALNVKYCEKHQKQANSDTYHHRRYEQGRDQFEAFYRTSAWKKMSRQ  61
             KK CNHAGC++L+    KYC KH+ +  +   ++R+  +G+  +  FY++ +W+K S  
Sbjct  3    VKKQCNHAGCKTLIDYRQKYCGKHKAKQTAIKREERKQSEGK--YFQFYQSRTWRKASYL  60

Query  62   MLIRSPICKLCYQEGVIRKADIVDHITPIREDWSRRLDWDNMQTLCIYHHNQKTNIENQR  121
              +  P+C  C +EG+IRKAD+VDH   +++DW+RRLD  N ++LC  HHN KT  E QR
Sbjct  61   YRLNHPVCEDCLEEGLIRKADVVDHKIELKDDWNRRLDETNFRSLCHAHHNSKTANERQR  120

Query  122  RIK  124
            R K
Sbjct  121  REK  123

14) LCAZH_1007 in NC_014334


> NC_017960_P1|9|G9|389869316|YP_006376739.1|Enterococcus_faecium_DO|-|6031..6411|-|HMPREF0351_12133|bacteriophage 
endonuclease
Length=126

 Score = 81.5 bits (290),  Expect = 4e-17, Method: Compositional matrix adjust.
 Identities = 48/110 (44%), Positives = 72/110 (66%), Gaps = 3/110 (2%)

Query  1    MIPFNQRFCEEHKQDKSKQATNQERMQYEEKELRFYKSTTWTKLSKSFRLRNPTCASCLK  60
            +I + Q++C  HK  K      +ER Q E K ++FY+S TW K S  +RL +P C  CL 
Sbjct  15   LIDYRQKYCGKHK-AKQTAIKREERKQSEGKYFQFYQSRTWRKASYLYRLNHPVCEDCLE  73

Query  61   RGIIRQAVLVDHIEPIKTAYGWQHRLDESNLQSLCQTCHNAKTAREVAQR  110
             G+IR+A +VDH   +K   +W++RLDE+N++SLC++ HN+KTA E  +R
Sbjct  74   EGLIRKADVVDHKIELKD--DWNRRLDETNFRSLCHAHHNSKTANERQRR  121