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No | Name | Start | End | Size(bp) | Insertion Site | Function |
1 | SPI-5 | 1155936 | 1161624 | 5689 | tRNA-ser | Effector proteins for SPI-1 and SPI-2 (SopB, SigD, PipB) |
2 | SPI-11 | 1350481 | 1366166 | 15686 | Gifsy-1 prophage | sopB, mppA, icdA, envF, msgA, envE, pagD, pagC |
3 | SPI-2 | 1497670 | 1539498 | 41829 | tRNA-val | Type III secretion system, required for systemic infection and intracellular pathogenesis by facilitating replication of intracellular bacteria within membrane-bound Salmonella-containing vacuoles |
4 | SPI-12 | 2354604 | 2365678 | 11075 | tRNA-pro | msgA, narP |
5 | SPI-1 | 2960260 | 3003747 | 43488 | fhlA/mutS | Type III secretion system, invasion into epithelial cells, apoptosis (InvA, OrgA, SptP, SipA, SipB, SipC, SipD, SopE, prgH) |
6 | SPI-3 | 3890879 | 3903697 | 12819 | tRNA-selC | Invasion, survival in monocytes, Mg2+ uptake (MgtC, B, MarT, MisL) |
7 | SPI-4 | 4411902 | 4438599 | 26698 | ssb/soxSR | Type I secretion system, putative toxin secretion, apoptosis, required for intracellular survival in macrophages, genes weakly similar to RTX-like toxins |
No | Start | End | Size(bp) | No. of ORFs | G+C content |
No. of homologs of PAI-virulence genes | PAIs homologous to this region |
1 | 290736 | 326505 | 35770 | 34 | 54.03 % | 4 | tcd island (Photorhabdus luminescens W14) SPI-6 (Salmonella enterica subsp. enterica serovar Typhi CT18) |
2 | 335030 | 355369 | 20340 | 20 | 46.31 % | 4 | SPI-6 (Salmonella enterica subsp. enterica serovar Typhi CT18) |
3 | 1155936 | 1175732 | 19797 | 25 | 50.91 % | 8 | tcd island (Photorhabdus luminescens W14) SPI-5 (Salmonella enterica 2229) SPI-5 (Salmonella typhimurium LT2) SPI-5 (Salmonella enterica subsp. enterica serovar Typhi CT18) SPI-5 (Salmonella enterica subsp. enterica serovar Choleraesuis str. SC-B67) |
4 | 1350481 | 1366008 | 15528 | 22 | 41.48 % | 3 | SPI-11 (Salmonella enterica subsp. enterica serovar Choleraesuis str. SC-B67) |
5 | 1497670 | 1539498 | 41829 | 49 | 47.46 % | 45 | LEE (Citrobacter rodentium DBS100) LEE (Escherichia coli E2348/69) LEE (Escherichia coli ATCC43895) LEE (Escherichia coli 71074) LEE (Escherichia coli 83/39) LEE (Escherichia coli RW1374) LEE (Escherichia coli RDEC-1) LEE (Escherichia coli O157:H7 EDL933) LEE (Escherichia coli O157:H7 Sakai) LEE (Escherichia coli 12009) LEE (Escherichia coli 11368) LEE (Escherichia coli 11128) LEE II (Escherichia coli 413/89-1) SPI-2 (Salmonella enterica LT2) SPI-2 (Salmonella enterica SL1344) SPI-2 (Salmonella typhimurium LT2) SPI-2 (Salmonella enterica subsp. enterica serovar Typhi CT18) SPI-2 (Salmonella enterica subsp. enterica serovar Typhi Ty2) SPI-2 (Salmonella enterica subsp. enterica serovar Choleraesuis str. SC-B67) SESS LEE (Salmonella enterica S1296) SESS LEE (Salmonella enterica S1635) Not named (Yersinia pestis CO92) |
6 | 2348398 | 2367946 | 19549 | 28 | 56.41 % | 1 | Not named (Cronobacter sakazakii ATCC BAA-894) PAGI-2(C) (Pseudomonas aeruginosa C) SPI-12 (Salmonella enterica subsp. enterica serovar Choleraesuis str. SC-B67) |
7 | 2871059 | 2880448 | 9390 | 5 | 56.44 % | 5 | PAI III 536 (Escherichia coli 536) |
8 | 2960260 | 3003747 | 43488 | 50 | 45.84 % | 37 | LIM (Escherichia coli O157:H7 Sakai) TTSS locus (Photorhabdus luminescens W14) SPI-1 (Salmonella typhimurium LT2) SPI-1 (Salmonella enterica subsp. enterica serovar Typhi CT18) SPI-1 (Salmonella enterica subsp. enterica serovar Typhi Ty2) SPI-1 (Salmonella enterica subsp. enterica serovar Choleraesuis str. SC-B67) centisome 63 pathogenicity island (Salmonella enterica SL1344) SSR-1 (Sodalis glossinidius ) SSR-2 (Sodalis glossinidius ) |
9 | 3890879 | 3905108 | 14230 | 14 | 47.98 % | 8 | SPI-3 (Salmonella enterica 14028s) SPI-3 (Salmonella typhimurium LT2) SPI-3 (Salmonella enterica subsp. enterica serovar Typhi CT18) SPI-3 (Salmonella enterica subsp. enterica serovar Choleraesuis str. SC-B67) |
10 | 4410904 | 4438910 | 28007 | 11 | 44.87 % | 9 | SPI-4 (Salmonella enterica LT2) SPI-4 (Salmonella enterica ST4/74) SPI-4 (Salmonella typhimurium LT2) SPI-4 (Salmonella enterica subsp. enterica serovar Typhi CT18) SPI-4 (Salmonella enterica subsp. enterica serovar Choleraesuis str. SC-B67) |
No | Start | End | Size(bp) | No. of ORFs | G+C content |
No. of homologs of PAI-virulence genes | PAIs homologous to this region |
1 | 2648332 | 2671481 | 23150 | 6 | 56.64 % | 5 | CS54 island (Salmonella enterica ATCC14028) |
No | Start | End | Size(bp) | No. of ORFs | G+C content |
No. of homologs of REI-resistance genes | REIs homologous to this region |
1 | 2113048 | 2121424 | 8377 | 11 | 52.21 % | 1 | PAI IV APEC-O1 (Escherichia coli APEC O1) |